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Involvement of the IP-10 chemokine in sarcoid granulomatous reactions. |
Agostini C, etal., J Immunol. 1998 Dec 1;161(11):6413-20.
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2. |
Critical role for CXCR3 chemokine biology in the pathogenesis of bronchiolitis obliterans syndrome. |
Belperio JA, etal., J Immunol. 2002 Jul 15;169(2):1037-49.
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3. |
CXCR3 polymorphisms associated with risk of asthma. |
Cheong HS, etal., Biochem Biophys Res Commun. 2005 Sep 9;334(4):1219-25.
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4. |
CXCR3-deficiency protects influenza-infected CCR5-deficient mice from mortality. |
Fadel SA, etal., Eur J Immunol. 2008 Dec;38(12):3376-87.
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5. |
Overexpression of IFN-induced protein 10 and its receptor CXCR3 in myasthenia gravis. |
Feferman T, etal., J Immunol. 2005 May 1;174(9):5324-31.
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6. |
Suppression of experimental autoimmune myasthenia gravis by inhibiting the signaling between IFN-gamma inducible protein 10 (IP-10) and its receptor CXCR3. |
Feferman T, etal., J Neuroimmunol. 2009 Apr 30;209(1-2):87-95. Epub 2009 Feb 20.
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7. |
CXC chemokine receptor 3 modulates bleomycin-induced pulmonary injury via involving inflammatory process. |
Gao JM, etal., Chin Med Sci J. 2006 Sep;21(3):152-6.
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8. |
Chemokine receptor expression on allergen-specific T cells in asthma and allergic bronchopulmonary aspergillosis. |
Garcia G, etal., Allergy. 2007 Feb;62(2):170-7.
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9. |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. |
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
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10. |
Mechanisms of host defense following severe acute respiratory syndrome-coronavirus (SARS-CoV) pulmonary infection of mice. |
Glass WG, etal., J Immunol. 2004 Sep 15;173(6):4030-9. doi: 10.4049/jimmunol.173.6.4030.
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11. |
An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema. |
Grumelli S, etal., PLoS Med. 2004 Oct;1(1):e8. Epub 2004 Oct 19.
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12. |
Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. |
Hartl D, etal., J Immunol. 2008 Dec 1;181(11):8053-67.
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13. |
Blockade of CXCR3 receptor:ligand interactions reduces leukocyte recruitment to the lung and the severity of experimental idiopathic pneumonia syndrome. |
Hildebrandt GC, etal., J Immunol. 2004 Aug 1;173(3):2050-9.
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14. |
Chemokine-directed migration of tumor-inhibitory neural progenitor cells towards an intracranially growing glioma. |
Honeth G, etal., Exp Cell Res. 2006 May 1;312(8):1265-76. Epub 2006 Jan 23.
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15. |
Increased numbers of immature plasma cells in peripheral blood specifically overexpress chemokine receptor CXCR3 and CXCR4 in patients with ulcerative colitis. |
Hosomi S, etal., Clin Exp Immunol. 2011 Feb;163(2):215-24. doi: 10.1111/j.1365-2249.2010.04290.x. Epub 2010 Nov 19.
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16. |
Regulation of pulmonary fibrosis by chemokine receptor CXCR3. |
Jiang D, etal., J Clin Invest. 2004 Jul;114(2):291-9.
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17. |
CXCR3 chemokine receptor-plasma IP10 interaction in patients with coronary artery disease. |
Kawamura A, etal., Circ J. 2003 Oct;67(10):851-4.
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18. |
Lymphoid follicle cells in chronic obstructive pulmonary disease overexpress the chemokine receptor CXCR3. |
Kelsen SG, etal., Am J Respir Crit Care Med. 2009 May 1;179(9):799-805. Epub 2009 Feb 12.
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19. |
Pathogenesis of herpetic stromal keratitis in CCR5- and/or CXCR3-deficient mice. |
Komatsu K, etal., Curr Eye Res. 2008 Sep;33(9):736-49. doi: 10.1080/02713680802344716.
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20. |
Minocycline modulates chemokine receptors but not interleukin-10 mRNA expression in hypoxic-ischemic neonatal rat brain. |
Kremlev SG, etal., J Neurosci Res. 2007 Aug 15;85(11):2450-9.
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21. |
Asthma severity is associated with an increase in both blood CXCR3+ and CCR4+ T cells. |
Kurashima K, etal., Respirology. 2006 Mar;11(2):152-7.
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22. |
CXCL10/CXCR3-mediated responses promote immunity to respiratory syncytial virus infection by augmenting dendritic cell and CD8(+) T cell efficacy. |
Lindell DM, etal., Eur J Immunol. 2008 Aug;38(8):2168-79.
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23. |
Expression of the CXC chemokine receptor 3 and its ligands in ischemia-reperfusion injury of liver in rats. |
Liu Z, etal., Transplant Proc. 2008 Jun;40(5):1300-2.
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24. |
C protein-induced myocarditis and subsequent dilated cardiomyopathy: rescue from death and prevention of dilated cardiomyopathy by chemokine receptor DNA therapy. |
Matsumoto Y, etal., J Immunol. 2004 Sep 1;173(5):3535-41.
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25. |
CXCR3 and its ligands in a murine model of obliterative bronchiolitis: regulation and function. |
Medoff BD, etal., J Immunol. 2006 Jun 1;176(11):7087-95.
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26. |
Rat ISS GO annotations from MGI mouse gene data--August 2006 |
MGD data from the GO Consortium
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27. |
CXCR3 is required for migration to dermal inflammation by normal and in vivo activated T cells: differential requirements by CD4 and CD8 memory subsets. |
Mohan K, etal., Eur J Immunol. 2005 Jun;35(6):1702-11.
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28. |
Chemokine production during hypersensitivity pneumonitis. |
Nance S, etal., Eur J Immunol. 2004 Mar;34(3):677-85.
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29. |
Electronic Transfer of LocusLink and RefSeq Data |
NCBI rat LocusLink and RefSeq merged data July 26, 2002
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30. |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
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31. |
KEGG Annotation Import Pipeline |
Pipeline to import KEGG annotations from KEGG into RGD
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32. |
Dysregulated expression of MIG/CXCL9, IP-10/CXCL10 and CXCL16 and their receptors in systemic sclerosis. |
Rabquer BJ, etal., Arthritis Res Ther. 2011 Feb 8;13(1):R18.
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33. |
GOA pipeline |
RGD automated data pipeline
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34. |
Data Import for Chemical-Gene Interactions |
RGD automated import pipeline for gene-chemical interactions
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35. |
Changes in helper lymphocyte chemokine receptor expression and elevation of IP-10 during acute respiratory syncytial virus infection in infants. |
Roe MF, etal., Pediatr Allergy Immunol. 2011 Mar;22(2):229-34. doi: 10.1111/j.1399-3038.2010.01032.x.
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36. |
Enhanced expression of interferon-inducible protein 10 associated with Th1 profiles of chemokine receptor in autoimmune pulmonary inflammation of MRL/lpr mice. |
Shiozawa F, etal., Arthritis Res Ther. 2004;6(1):R78-R86. Epub 2003 Nov 19.
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37. |
CXCR3 blockade inhibits T-cell migration into the CNS during EAE and prevents development of adoptively transferred, but not actively induced, disease. |
Sporici R and Issekutz TB, Eur J Immunol. 2010 Oct;40(10):2751-61.
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38. |
Antihypertensive therapy induces compartment-specific chemokine expression and a Th1 immune response in the clipped kidney of Goldblatt hypertensive rats. |
Steinmetz OM, etal., Am J Physiol Renal Physiol. 2007 Feb;292(2):F876-87. Epub 2006 Oct 24.
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39. |
Chemokine receptors in a regulation of interstitial lung fibrosis and inflammation. |
Sterclova M, etal., Exp Lung Res. 2009 Aug;35(6):514-23.
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40. |
A small-molecule compound targeting CCR5 and CXCR3 prevents airway hyperresponsiveness and inflammation. |
Suzaki Y, etal., Eur Respir J. 2008 Apr;31(4):783-9. Epub 2007 Dec 19.
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41. |
Transmural inflammation by interferon-gamma-producing T cells correlates with outward vascular remodeling and intimal expansion of ascending thoracic aortic aneurysms. |
Tang PC, etal., FASEB J. 2005 Sep;19(11):1528-30. Epub 2005 Jul 12.
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42. |
Multiple chemokine receptors, including CCR6 and CXCR3, regulate antigen-induced T cell homing to the human asthmatic airway. |
Thomas SY, etal., J Immunol. 2007 Aug 1;179(3):1901-12.
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43. |
Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions. |
Verge GM, etal., Eur J Neurosci 2004 Sep;20(5):1150-60.
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44. |
Antagonism of CXCR3 inhibits lung metastasis in a murine model of metastatic breast cancer. |
Walser TC, etal., Cancer Res. 2006 Aug 1;66(15):7701-7.
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45. |
Identification and molecular characterization of rat CXCR3: receptor expression and interferon-inducible protein-10 binding are increased in focal stroke. |
Wang X, etal., Mol Pharmacol 2000 Jun;57(6):1190-8.
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46. |
CXCR3 and its ligands participate in the host response to Bordetella bronchiseptica infection of the mouse respiratory tract but are not required for clearance of bacteria from the lung. |
Widney DP, etal., Infect Immun. 2005 Jan;73(1):485-93.
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