GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621528
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cxcr3
Name: C-X-C motif chemokine receptor 3
Acc ID: CHEBI:22984
Term: calcium atom
Definition: An alkaline earth metal atom that has formula Ca.
Chemical ID: MESH:D002118
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects abundanceISORGD:13504476480464CTDCXCR3 protein affects the abundance of Calcium

PMID:12055238
multiple interactionsISORGD:13504476480464CTD[[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium] which results in increased expression of EGR1 mRNA

[CXCL10 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium

[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium

[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium

PMID:12517959, PMID:25833952
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.