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Gene: CXCR3 (C-X-C motif chemokine receptor 3) Homo sapiens
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Symbol: CXCR3
Name: C-X-C motif chemokine receptor 3
Description: Exhibits C-X-C chemokine binding activity; identical protein binding activity; and signaling receptor activity. Involved in several processes, including chemokine (C-C motif) ligand 11 production; regulation of angiogenesis; and regulation of execution phase of apoptosis. Localizes to plasma membrane. Implicated in asthma. Biomarker of several diseases, including artery disease (multiple); cystic fibrosis; lung disease (multiple); myasthenia gravis; and ulcerative colitis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C-X-C chemokine receptor type 3; CD182; CD183; chemokine (C-X-C motif) receptor 3; chemokine (C-X-C) receptor 3; chemokine receptor 3; CKR-L2; CMKAR3; CXC-R3; CXCR-3; G protein-coupled receptor 9; GPR9; interferon-inducible protein 10 receptor; IP-10 receptor; IP10 receptor; IP10-R; Mig receptor; Mig-R; MigR
Orthologs:
Mus musculus (house mouse) : Cxcr3 (chemokine (C-X-C motif) receptor 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cxcr3 (C-X-C motif chemokine receptor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cxcr3 (C-X-C motif chemokine receptor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : CXCR3 (C-X-C motif chemokine receptor 3)
Canis lupus familiaris (dog) : CXCR3 (C-X-C motif chemokine receptor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cxcr3 (C-X-C motif chemokine receptor 3)
Sus scrofa (pig) : CXCR3 (C-X-C motif chemokine receptor 3)
Chlorocebus sabaeus (African green monkey) : CXCR3 (C-X-C motif chemokine receptor 3)
Heterocephalus glaber (naked mole-rat) : Cxcr3 (C-X-C motif chemokine receptor 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX71,615,916 - 71,618,511 (-)EnsemblGRCh38hg38GRCh38
GRCh38X71,615,913 - 71,618,515 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X70,835,766 - 70,838,367 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X70,752,491 - 70,755,092 (-)NCBINCBI36hg18NCBI36
Build 34X70,618,787 - 70,621,388NCBI
CeleraX71,188,006 - 71,190,607 (-)NCBI
Cytogenetic MapXq13.1NCBI
HuRefX64,650,668 - 64,653,542 (-)NCBIHuRef
CHM1_1X70,728,177 - 70,730,778 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CXCR3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350447
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.