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Gene: Cxcl10 (chemokine (C-X-C motif) ligand 10) Mus musculus
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Symbol: Cxcl10
Name: chemokine (C-X-C motif) ligand 10
RGD ID: 1550709
Description: Predicted to have CXCR3 chemokine receptor binding activity; heparin binding activity; and receptor ligand activity. Involved in defense response to virus; negative regulation of cell differentiation; and response to bacterium. Localizes to external side of plasma membrane and extracellular space. Is expressed in several structures, including alimentary system; axial skeleton; hemolymphoid system; and liver. Human ortholog(s) of this gene implicated in hepatitis B; middle cerebral artery infarction; and type 1 diabetes mellitus. Orthologous to human CXCL10 (C-X-C motif chemokine ligand 10); PARTICIPATES IN influenza A pathway; Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; Toll-like receptor signaling pathway; INTERACTS WITH (+)-alpha-viniferin; 1,4-phenylenediamine; 1-chloro-2,4-dinitrobenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 10 kDa interferon gamma-induced protein; C-X-C motif chemokine 10; C7; CRG-; CRG-2; gamma-IP10; gIP-; gIP-10; Ifi; Ifi10; IN; INP10; interferon activated gene 10; interferon-gamma induced protein CRG-2; interferon-gamma-induced protein CRG-2; IP; IP-; IP-10; IP10; mob-; mob-1; Scyb1; Scyb10; small inducible cytokine B subfamily (Cys-X-Cys), member 10; small-inducible cytokine B10
Orthologs:
Homo sapiens (human) : CXCL10 (C-X-C motif chemokine ligand 10)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cxcl10 (C-X-C motif chemokine ligand 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cxcl10 (C-X-C motif chemokine ligand 10)
Pan paniscus (bonobo/pygmy chimpanzee) : CXCL10 (C-X-C motif chemokine ligand 10)
Canis lupus familiaris (dog) : CXCL10 (C-X-C motif chemokine ligand 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cxcl10 (C-X-C motif chemokine ligand 10)
Sus scrofa (pig) : CXCL10 (C-X-C motif chemokine ligand 10)
Chlorocebus sabaeus (African green monkey) : CXCL10 (C-X-C motif chemokine ligand 10)
Heterocephalus glaber (naked mole-rat) : Cxcl10 (C-X-C motif chemokine ligand 10)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39592,494,497 - 92,496,748 (-)NCBI
GRCm38592,346,638 - 92,348,889 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl592,346,638 - 92,348,889 (-)EnsemblGRCm38mm10GRCm38
MGSCv37592,775,667 - 92,777,880 (-)NCBIGRCm37mm9NCBIm37
MGSCv36593,421,841 - 93,424,054 (-)NCBImm8
Celera590,490,436 - 90,492,644 (-)NCBICelera
Cytogenetic Map5E2NCBI
cM Map546.57NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cxcl10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550709
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.