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Gene: Cxcl10 (chemokine (C-X-C motif) ligand 10) Mus musculus
Symbol: Cxcl10
Name: chemokine (C-X-C motif) ligand 10
RGD ID: 1550709
Description: Predicted to have CXCR3 chemokine receptor binding activity; heparin binding activity; and receptor ligand activity. Involved in defense response to virus; negative regulation of cell differentiation; and response to bacterium. Localizes to external side of plasma membrane and extracellular space. Is expressed in several structures, including alimentary system; axial skeleton; hemolymphoid system; and liver. Human ortholog(s) of this gene implicated in hepatitis B; middle cerebral artery infarction; and type 1 diabetes mellitus. Orthologous to human CXCL10 (C-X-C motif chemokine ligand 10); PARTICIPATES IN influenza A pathway; Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; Toll-like receptor signaling pathway; INTERACTS WITH (+)-alpha-viniferin; 1,4-phenylenediamine; 1-chloro-2,4-dinitrobenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 10 kDa interferon gamma-induced protein; C-X-C motif chemokine 10; C7; CRG-; CRG-2; gamma-IP10; gIP-; gIP-10; Ifi; Ifi10; IN; INP10; interferon activated gene 10; interferon-gamma induced protein CRG-2; interferon-gamma-induced protein CRG-2; IP; IP-; IP-10; IP10; mob-; mob-1; Scyb1; Scyb10; small inducible cytokine B subfamily (Cys-X-Cys), member 10; small-inducible cytokine B10
Homo sapiens (human) : CXCL10 (C-X-C motif chemokine ligand 10)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cxcl10 (C-X-C motif chemokine ligand 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cxcl10 (C-X-C motif chemokine ligand 10)
Pan paniscus (bonobo/pygmy chimpanzee) : CXCL10 (C-X-C motif chemokine ligand 10)
Canis lupus familiaris (dog) : CXCL10 (C-X-C motif chemokine ligand 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cxcl10 (C-X-C motif chemokine ligand 10)
Sus scrofa (pig) : CXCL10 (C-X-C motif chemokine ligand 10)
Chlorocebus sabaeus (African green monkey) : CXCL10 (C-X-C motif chemokine ligand 10)
Heterocephalus glaber (naked mole-rat) : Cxcl10 (C-X-C motif chemokine ligand 10)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39592,494,497 - 92,496,748 (-)NCBI
GRCm38592,346,638 - 92,348,889 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl592,346,638 - 92,348,889 (-)EnsemblGRCm38mm10GRCm38
MGSCv37592,775,667 - 92,777,880 (-)NCBIGRCm37mm9NCBIm37
MGSCv36593,421,841 - 93,424,054 (-)NCBImm8
Celera590,490,436 - 90,492,644 (-)NCBICelera
Cytogenetic Map5E2NCBI
cM Map546.57NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cxcl10
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550709
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.