CXCR3 (C-X-C motif chemokine receptor 3) - Rat Genome Database

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Gene: CXCR3 (C-X-C motif chemokine receptor 3) Canis lupus familiaris
Analyze
Symbol: CXCR3
Name: C-X-C motif chemokine receptor 3
RGD ID: 12362937
Description: ENCODES a protein that exhibits C-X-C chemokine binding (ortholog); C-X-C chemokine receptor activity (ortholog); signaling receptor activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); calcium-mediated signaling (ortholog); cell surface receptor signaling pathway (ortholog); ASSOCIATED WITH allergic disease (ortholog); alopecia areata (ortholog); asthma (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C-X-C chemokine receptor type 3; chemokine (C-X-C motif) receptor 3; interferon-inducible protein 10 receptor; IP-10 receptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X55,882,433 - 55,884,582 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX55,882,433 - 55,884,582 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX46,709,139 - 46,711,288 (-)NCBI
ROS_Cfam_1.0X56,851,684 - 56,853,833 (-)NCBI
ROS_Cfam_1.0 EnsemblX56,851,193 - 56,853,833 (-)Ensembl
UMICH_Zoey_3.1X54,818,992 - 54,821,141 (-)NCBI
UNSW_CanFamBas_1.0X56,150,994 - 56,153,143 (-)NCBI
UU_Cfam_GSD_1.0X56,078,430 - 56,080,579 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

Genomics

Comparative Map Data
CXCR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X55,882,433 - 55,884,582 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX55,882,433 - 55,884,582 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX46,709,139 - 46,711,288 (-)NCBI
ROS_Cfam_1.0X56,851,684 - 56,853,833 (-)NCBI
ROS_Cfam_1.0 EnsemblX56,851,193 - 56,853,833 (-)Ensembl
UMICH_Zoey_3.1X54,818,992 - 54,821,141 (-)NCBI
UNSW_CanFamBas_1.0X56,150,994 - 56,153,143 (-)NCBI
UU_Cfam_GSD_1.0X56,078,430 - 56,080,579 (-)NCBI
CXCR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X71,615,919 - 71,618,511 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 EnsemblX71,615,916 - 71,618,511 (-)EnsemblGRCh38hg38GRCh38
GRCh37X70,835,769 - 70,838,361 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X70,752,491 - 70,755,092 (-)NCBINCBI36hg18NCBI36
Build 34X70,618,787 - 70,621,388NCBI
CeleraX71,188,006 - 71,190,607 (-)NCBI
Cytogenetic MapXq13.1NCBI
HuRefX64,650,668 - 64,653,542 (-)NCBIHuRef
CHM1_1X70,728,177 - 70,730,778 (-)NCBICHM1_1
T2T-CHM13v2.0X70,049,169 - 70,051,761 (-)NCBI
Cxcr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X100,775,141 - 100,777,753 (-)NCBIGRCm39mm39
GRCm39 EnsemblX100,775,141 - 100,777,875 (-)Ensembl
GRCm38X101,731,535 - 101,734,147 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX101,731,535 - 101,734,269 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X98,926,875 - 98,929,486 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X97,934,255 - 97,936,866 (-)NCBImm8
CeleraX88,649,308 - 88,651,919 (-)NCBICelera
Cytogenetic MapXDNCBI
cM MapX44.58NCBI
Cxcr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X66,844,318 - 66,846,969 (-)NCBImRatBN7.2
mRatBN7.2 EnsemblX66,844,318 - 66,846,969 (-)Ensembl
Rnor_6.0X71,614,346 - 71,616,997 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX71,614,346 - 71,616,997 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X72,463,681 - 72,466,332 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X89,794,276 - 89,796,927 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X89,867,709 - 89,870,360 (-)NCBI
CeleraX67,199,203 - 67,201,854 (-)NCBICelera
Cytogenetic MapXq22NCBI
Cxcr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547511,148,879 - 11,152,596 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547511,148,928 - 11,152,313 (-)NCBIChiLan1.0ChiLan1.0
CXCR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X70,933,160 - 70,935,756 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX70,933,160 - 70,935,756 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X60,880,759 - 60,883,355 (-)NCBIMhudiblu_PPA_v0panPan3
Cxcr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X46,283,637 - 46,307,589 (+)NCBI
SpeTri2.0NW_00493676266,636 - 69,694 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CXCR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX57,592,038 - 57,595,692 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X57,592,032 - 57,595,706 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X65,033,696 - 65,037,066 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CXCR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X61,430,723 - 61,433,777 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 EnsemblX61,430,725 - 61,433,386 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660653,300,128 - 3,302,726 (-)NCBIVero_WHO_p1.0
Cxcr3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249031,958,698 - 1,961,763 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046249031,958,323 - 1,961,789 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 5 4 1 6 1 5 7 2
Below cutoff 5 18 5 5 1 2 9 2 3 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000027154   ⟹   ENSCAFP00000025254
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX55,882,433 - 55,884,582 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845033811   ⟹   ENSCAFP00845026459
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 EnsemblX56,851,193 - 56,853,833 (-)Ensembl
RefSeq Acc Id: NM_001011887   ⟹   NP_001011887
RefSeq Status: VALIDATED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1X55,882,433 - 55,884,582 (-)NCBI
Dog10K_Boxer_TashaX46,709,139 - 46,711,288 (-)NCBI
ROS_Cfam_1.0X56,851,684 - 56,853,833 (-)NCBI
UMICH_Zoey_3.1X54,818,992 - 54,821,141 (-)NCBI
UNSW_CanFamBas_1.0X56,150,994 - 56,153,143 (-)NCBI
UU_Cfam_GSD_1.0X56,078,430 - 56,080,579 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001011887 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAD86855 (Get FASTA)   NCBI Sequence Viewer  
  Q5KSK8 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001011887   ⟸   NM_001011887
- Sequence:
RefSeq Acc Id: ENSCAFP00000025254   ⟸   ENSCAFT00000027154
RefSeq Acc Id: ENSCAFP00845026459   ⟸   ENSCAFT00845033811
Protein Domains
G_PROTEIN_RECEP_F1_2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017146 Ensembl
  ENSCAFG00845019157 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00845026459 ENTREZGENE
  ENSCAFP00845026459.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00845033811 ENTREZGENE
  ENSCAFT00845033811.1 UniProtKB/TrEMBL
InterPro Chemokine_CXCR3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene CXCR3 ENTREZGENE
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS CCCHEMOKINER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CXCCHMKINER3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I3NXJ3_CANLF UniProtKB/TrEMBL
  CXCR3_CANLF UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:39750 ENTREZGENE