Gene: RT1-Db1 (RT1 class II, locus Db1) Rattus norvegicus
Symbol: RT1-Db1
Name: RT1 class II, locus Db1
Description: ENCODES a protein that exhibits CD4 receptor binding (ortholog); peptide antigen binding (ortholog); INVOLVED IN response to dexamethasone; response to organic substance; antigen processing and presentation of exogenous peptide antigen via MHC class II (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; allograft rejection pathway; antigen processing and presentation pathway; ASSOCIATED WITH Liver Cirrhosis, Experimental; Pneumocystis Infections; Actinic Prurigo (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); late endosome membrane (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 2,2',5,5'-tetrachlorobiphenyl
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Db1; MGC105710; MHC class II RT1D beta1 chain antigen; rano class II histocompatibility antigen, D-1 beta chain; RT1 class II histocompatibility antigen, D-1 beta chain; RT1 class II, locus Db1 (mapped); RT1-D beta; RT1-Db; RT1-Db1_mapped; RT1-Db1n
Is Marker For: Strains:   DA.KHW-(RT1-Db1-RT1-DMb)  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0204,087,621 - 4,097,190 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0206,167,759 - 6,177,328 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,671,489 - 4,681,058 (-)NCBIRGSC3.4rn4RGSC3.4
Celera206,150,824 - 6,160,393 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on RT1-Db1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1593282
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2018-03-13
Status: ACTIVE