Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Cers1 (ceramide synthase 1) Rattus norvegicus
Symbol: Cers1
Name: ceramide synthase 1
Description: Predicted to have cytokine activity; sphingosine N-acyltransferase activity; and transforming growth factor beta receptor binding activity. Predicted to be involved in several processes, including cellular response to UV-A; regulation of protein phosphorylation; and transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to localize to the endoplasmic reticulum and extracellular space. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy. Orthologous to human CERS1 (ceramide synthase 1); INTERACTS WITH acrylamide; bisphenol A; furan.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: LAG1 homolog, ceramide synthase 1; LAG1 homolog, ceramide synthase 1 (S. cerevisiae); LAG1 longevity assurance homolog 1; LAG1 longevity assurance homolog 1 (S. cerevisiae); Lass1; LOC290658; longevity assurance homolog 1; longevity assurance homolog 1 (S. cerevisiae); longevity assurance-like protein 1
Homo sapiens (human) : CERS1 (ceramide synthase 1)  HGNC  Alliance
Mus musculus (house mouse) : Cers1 (ceramide synthase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cers1 (ceramide synthase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CERS1 (ceramide synthase 1)
Canis lupus familiaris (dog) : CERS1 (ceramide synthase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cers1 (ceramide synthase 1)
Sus scrofa (pig) : CERS1 (ceramide synthase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01620,845,580 - 20,860,789 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,845,576 - 20,860,789 (-)Ensembl
Rnor_5.01620,698,122 - 20,712,564 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,580,807 - 19,596,415 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11619,588,709 - 19,596,385 (-)NCBI
Celera1619,287,577 - 19,302,834 (-)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Cers1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305974
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.