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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:carpal tunnel syndrome
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Accession:DOID:12169 term browser browse the term
Definition:Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45)
Synonyms:exact_synonym: CARPAL TUNNEL SYNDROME, FAMILIAL;   CTS;   CTS - carpal tunnel syndrome;   Carpal Tunnel Syndromes;   Compression Neuropathy, Carpal Tunnel;   Entrapment Neuropathy, Carpal Tunnel;   Median nerve entrapment;   carpal tunnel median neuropathy;   thenar amyotrophy of carpal origin
 primary_id: MESH:D002349
 xref: ICD10CM:G56.0;   ICD9CM:354.0;   NCI:C34450;   OMIM:PS115430
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
carpal tunnel syndrome term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ttr transthyretin ISO ClinVar Annotator: match by term: Carpal tunnel syndrome, familial
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: AMYOTROPHY, THENAR, OF CARPAL ORIGIN
ClinVar
CTD
PMID:192115 PMID:1351039 PMID:1353008 PMID:1358785 PMID:1490495 PMID:1547960 PMID:1570831 PMID:1867256 PMID:1977686 PMID:1992765 PMID:1997217 PMID:2002274 PMID:2046936 PMID:2063870 PMID:2237288 PMID:2320592 PMID:2349941 PMID:2564060 PMID:2590199 PMID:2624269 PMID:2646319 PMID:2714785 PMID:2856994 PMID:2857043 PMID:2896079 PMID:3011930 PMID:3022107 PMID:3022108 PMID:3022697 PMID:3030336 PMID:3229002 PMID:3457802 PMID:3479441 PMID:3627183 PMID:3908483 PMID:3934968 PMID:4079954 PMID:4138132 PMID:4354899 PMID:5507249 PMID:5652991 PMID:5799493 PMID:6087811 PMID:6100724 PMID:6208668 PMID:6311926 PMID:6549130 PMID:6583672 PMID:6651852 PMID:6736244 PMID:6782125 PMID:7389759 PMID:7839813 PMID:7868124 PMID:8064809 PMID:8071954 PMID:8100581 PMID:8194279 PMID:8309582 PMID:8563114 PMID:8698351 PMID:8721565 PMID:8778271 PMID:8857732 PMID:9017939 PMID:9215058 PMID:9475090 PMID:10453736 PMID:10465115 PMID:10488818 PMID:10506096 PMID:10529370 PMID:10762172 PMID:10842715 PMID:11385707 PMID:11709003 PMID:11752419 PMID:11752443 PMID:11940682 PMID:12050338 PMID:12217248 PMID:12433265 PMID:12566023 PMID:12617705 PMID:12874413 PMID:12874414 PMID:14569203 PMID:14640030 PMID:14673473 PMID:14986482 PMID:15123043 PMID:15185492 PMID:15249622 PMID:15299606 PMID:15523922 PMID:15820680 PMID:15930086 PMID:16011990 PMID:16194874 PMID:16194875 PMID:16432141 PMID:16631014 PMID:16631015 PMID:17251346 PMID:17503405 PMID:17698792 PMID:18276611 PMID:18318779 PMID:18460047 PMID:18606975 PMID:18830126 PMID:18863976 PMID:18925456 PMID:19364362 PMID:19602727 PMID:19709674 PMID:19781421 PMID:19808383 PMID:20209591 PMID:20301373 PMID:20435197 PMID:21600538 PMID:22083004 PMID:22184092 PMID:22382560 PMID:22531659 PMID:22592564 PMID:22620962 PMID:22745357 PMID:22877808 PMID:22995991 PMID:23080516 PMID:23279339 PMID:23387326 PMID:23414091 PMID:23713495 PMID:23716704 PMID:23833285 PMID:23993291 PMID:24033266 PMID:24046394 PMID:24073013 PMID:24131106 PMID:24164154 PMID:24184229 PMID:24455802 PMID:24474780 PMID:24517438 PMID:24555660 PMID:24601850 PMID:24633258 PMID:24800914 PMID:24818650 PMID:24945718 PMID:25225131 PMID:25395306 PMID:25550818 PMID:25551524 PMID:25741868 PMID:25819286 PMID:25846356 PMID:26115788 PMID:26123279 PMID:26428663 PMID:26467025 PMID:26537620 PMID:27188913 PMID:27386769 PMID:27793437 PMID:27838833 PMID:28492532 PMID:28635949 PMID:29121657 PMID:30811423 PMID:30953182 PMID:31135624 PMID:31821430 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link
Carpal Tunnel Syndrome 1 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ttr transthyretin ISO OMIM NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link
Carpal Tunnel Syndrome 2 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comp cartilage oligomeric matrix protein ISO ClinVar Annotator: match by term: Carpal tunnel syndrome 2
ClinVar Annotator: match by term: CARPAL TUNNEL SYNDROME 2
OMIM
ClinVar
PMID:12483304 PMID:14684695 PMID:21834907 PMID:21965141 PMID:24595329 PMID:25741868 PMID:28492532 PMID:32686688 NCBI chr16:20,798,437...20,807,070
Ensembl chr16:20,798,437...20,807,070
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17126
    syndrome 8015
      nerve compression syndrome 4
        carpal tunnel syndrome 2
          Carpal Tunnel Syndrome 1 1
          Carpal Tunnel Syndrome 2 1
Path 2
Term Annotations click to browse term
  disease 17126
    disease of anatomical entity 16474
      nervous system disease 12073
        peripheral nervous system disease 2516
          neuropathy 2316
            neuritis 195
              mononeuritis 140
                mononeuritis of upper limb and mononeuritis multiplex 12
                  median neuropathy 12
                    carpal tunnel syndrome 2
                      Carpal Tunnel Syndrome 1 1
                      Carpal Tunnel Syndrome 2 1
paths to the root