Gene: Notch2 (notch 2) Rattus norvegicus
Symbol: Notch2
Name: notch 2
Description: ENCODES a protein that exhibits enzyme binding (ortholog); NF-kappaB binding (ortholog); INVOLVED IN cell fate determination; tissue regeneration; wound healing; PARTICIPATES IN altered Notch signaling pathway; Notch signaling pathway; Notch signaling pathway; ASSOCIATED WITH Carotid Artery Injuries; Alagille syndrome (ortholog); astrocytoma (ortholog); FOUND IN cell surface (ortholog); cilium (ortholog); integral component of plasma membrane (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; 3-methylcholanthrene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: neurogenic locus notch homolog protein 2; notch gene homolog 2; notch gene homolog 2 (Drosophila); Notch homolog 2; Notch homolog 2 (Drosophila)
Homo sapiens (human) : NOTCH2 (notch receptor 2)  HGNC  Alliance
Mus musculus (house mouse) : Notch2 (notch 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Notch2 (notch receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NOTCH2 (notch receptor 2)
Canis lupus familiaris (dog) : NOTCH2 (notch receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Notch2 (notch receptor 2)
Sus scrofa (pig) : NOTCH2 (notch receptor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02200,187,184 - 200,320,403 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02207,597,473 - 207,599,560 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.02219,662,511 - 219,793,306 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42192,839,350 - 192,986,589 (+)NCBIRGSC3.4rn4RGSC3.4
Celera2178,101,416 - 178,234,556 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Notch2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3188
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE