Gene: Notch2 (notch 2) Rattus norvegicus
Symbol: Notch2
Name: notch 2
Description: ENCODES a protein that exhibits enzyme binding (ortholog); NF-kappaB binding (ortholog); INVOLVED IN cell fate determination; tissue regeneration; wound healing; PARTICIPATES IN altered Notch signaling pathway; Notch signaling pathway; Notch signaling pathway; ASSOCIATED WITH Carotid Artery Injuries; Alagille Syndrome (ortholog); Astrocytoma (ortholog); FOUND IN cell surface (ortholog); cilium (ortholog); integral component of plasma membrane (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: neurogenic locus notch homolog protein 2; notch gene homolog 2; notch gene homolog 2 (Drosophila); Notch homolog 2; Notch homolog 2 (Drosophila)
Homo sapiens (human) : NOTCH2 (notch 2)  HGNC  Alliance
Mus musculus (house mouse) : Notch2 (notch 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Notch2 (notch 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NOTCH2 (notch 2)
Canis lupus familiaris (dog) : NOTCH2 (notch 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Notch2 (notch 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02200,187,184 - 200,320,403 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02207,597,473 - 207,599,560 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.02219,662,511 - 219,793,306 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42192,839,350 - 192,986,589 (+)NCBIRGSC3.4rn4RGSC3.4
Celera2178,101,416 - 178,234,556 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Notch2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3188
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-03-13
Status: ACTIVE