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Gene: Pdgfd (platelet derived growth factor D) Rattus norvegicus
Symbol: Pdgfd
Name: platelet derived growth factor D
Description: Predicted to have platelet-derived growth factor receptor binding activity. Involved in several processes, including cellular response to growth factor stimulus; positive regulation of cell migration; and positive regulation of cell population proliferation. Localizes to extracellular space. Used to study glomerulonephritis and mesangial proliferative glomerulonephritis. Biomarker of liver cirrhosis; mesangial proliferative glomerulonephritis; and myocardial infarction. Human ortholog(s) of this gene implicated in prostatic hypertrophy. Orthologous to human PDGFD (platelet derived growth factor D); PARTICIPATES IN platelet-derived growth factor signaling pathway; melanoma pathway; prostate cancer pathway; INTERACTS WITH 17beta-estradiol; aflatoxin B1; bisphenol A.
Type: protein-coding
Also known as: iris-expressed growth factor; PDGF-D; platelet-derived growth factor D; platelet-derived growth factor, D polypeptide; rSCDGF-B; SCDGF-B; Scdgfb; spinal cord-derived growth factor B; spinal-cord derived growth factor-B protein
Homo sapiens (human) : PDGFD (platelet derived growth factor D)  HGNC  Alliance
Mus musculus (house mouse) : Pdgfd (platelet-derived growth factor, D polypeptide)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdgfd (platelet derived growth factor D)
Pan paniscus (bonobo/pygmy chimpanzee) : PDGFD (platelet derived growth factor D)
Canis lupus familiaris (dog) : PDGFD (platelet derived growth factor D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdgfd (platelet derived growth factor D)
Sus scrofa (pig) : PDGFD (platelet derived growth factor D)
Chlorocebus sabaeus (African green monkey) : PDGFD (platelet derived growth factor D)
Heterocephalus glaber (naked mole-rat) : Pdgfd (platelet derived growth factor D)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.084,441,010 - 4,666,754 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl84,440,876 - 4,669,014 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.084,454,510 - 4,682,165 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.483,326,218 - 3,341,300 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.183,125,520 - 3,341,300 (+)NCBI
Celera85,067,751 - 5,287,344 (+)NCBICelera
Cytogenetic Map8q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Pdgfd
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621880
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.