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Gene: Atg7 (autophagy related 7) Rattus norvegicus
Symbol: Atg7
Name: autophagy related 7
RGD ID: 1304817
Description: Predicted to have protein homodimerization activity; transcription factor binding activity; and ubiquitin-like modifier activating enzyme activity. Involved in several processes, including cellular response to morphine; negative regulation of mitochondrial DNA replication; and negative regulation of oxidative stress-induced neuron death. Localizes to axon. Used to study malignant glioma. Biomarker of hypertension; myocardial infarction; neurodegenerative disease; and paraplegia. Orthologous to human ATG7 (autophagy related 7); PARTICIPATES IN autophagy pathway; mitochondrial autophagy pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2-methoxyethanol.
Type: protein-coding
Also known as: APG7-like; Apg7l; ATG12-activating enzyme E1 ATG7; ATG7 autophagy related 7 homolog; ATG7 autophagy related 7 homolog (S. cerevisiae); autophagy 7-like; autophagy 7-like (S. cerevisiae); autophagy related 7 homolog; autophagy related 7 homolog (S. cerevisiae); autophagy-related 7; autophagy-related 7 (yeast); autophagy-related protein 7; LOC312647; ubiquitin-activating enzyme E1-like protein; ubiquitin-like modifier-activating enzyme ATG7
Homo sapiens (human) : ATG7 (autophagy related 7)  HGNC  Alliance
Mus musculus (house mouse) : Atg7 (autophagy related 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atg7 (autophagy related 7)
Pan paniscus (bonobo/pygmy chimpanzee) : ATG7 (autophagy related 7)
Canis lupus familiaris (dog) : ATG7 (autophagy related 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atg7 (autophagy related 7)
Sus scrofa (pig) : ATG7 (autophagy related 7)
Chlorocebus sabaeus (African green monkey) : ATG7 (autophagy related 7)
Heterocephalus glaber (naked mole-rat) : Atg7 (autophagy related 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04146,570,113 - 146,777,093 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4146,598,413 - 146,777,124 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04209,861,459 - 210,067,618 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44150,814,706 - 150,992,704 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14151,059,546 - 151,153,422 (+)NCBI
Celera4136,643,475 - 136,821,326 (+)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Atg7
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1304817
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.