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Gene: F7 (coagulation factor VII) Rattus norvegicus
Symbol: F7
Name: coagulation factor VII
Description: Exhibits endopeptidase activity and signaling receptor binding activity. Predicted to contribute to serine-type endopeptidase activity. Involved in several processes, including response to genistein; response to peptide hormone; and response to thyroxine. Localizes to the extracellular space and vesicle. Used to study asthma; diabetes mellitus; and type 2 diabetes mellitus. Biomarker of several diseases, including bilirubin metabolic disorder; familial hyperlipidemia; hypertension; hypothyroidism; and prothrombin deficiency. Human ortholog(s) of this gene implicated in several diseases, including acute pancreatitis; artery disease (multiple); diabetes mellitus (multiple); inherited blood coagulation disease (multiple); and obesity. Orthologous to human F7 (coagulation factor VII); PARTICIPATES IN coagulation cascade pathway; acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; INTERACTS WITH 17beta-estradiol; acenocoumarol; ammonium chloride.
Type: protein-coding
Also known as: coagulation factor VII (serum prothrombin conversion accelerator); serum prothrombin conversion accelerator
Homo sapiens (human) : F7 (coagulation factor VII)  HGNC  Alliance
Mus musculus (house mouse) : F7 (coagulation factor VII)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : F7 (coagulation factor VII)
Pan paniscus (bonobo/pygmy chimpanzee) : F7 (coagulation factor VII)
Canis lupus familiaris (dog) : F7 (coagulation factor VII)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : F7 (coagulation factor VII)
Sus scrofa (pig) : F7 (coagulation factor VII)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01681,824,610 - 81,834,923 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01681,309,476 - 81,320,833 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41681,348,678 - 81,358,991 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11681,348,942 - 81,359,256 (-)NCBI
Celera1674,296,307 - 74,306,282 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on F7
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 628678
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.