F7 (coagulation factor VII) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: F7 (coagulation factor VII) Ictidomys tridecemlineatus
Analyze
Symbol: F7
Name: coagulation factor VII
RGD ID: 12580408
Description: ENCODES a protein that exhibits endopeptidase activity (ortholog); serine-type endopeptidase activity (ortholog); signaling receptor binding (ortholog); INVOLVED IN animal organ regeneration (ortholog); blood coagulation (ortholog); circadian rhythm (ortholog); PARTICIPATES IN acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; aminocaproic acid pharmacodynamics pathway; ASSOCIATED WITH Acquired Angioedema (ortholog); acute pancreatitis (ortholog); Angina, Stable (ortholog); FOUND IN extracellular space (ortholog); serine-type peptidase complex (ortholog); vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936472505,751 - 515,375 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acquired Angioedema  (ISO)
acute pancreatitis  (ISO)
Albuminuria  (ISO)
Angina, Stable  (ISO)
Animal Disease Models  (ISO)
Arterial Thrombosis  (ISO)
arteriosclerosis  (ISO)
asthma  (ISO)
bilirubin metabolic disorder  (ISO)
blood coagulation disease  (ISO)
breast cancer  (ISO)
Cerebral Hemorrhage  (ISO)
cerebral infarction  (ISO)
Choroidal Neovascularization  (ISO)
Chronic Allograft Dysfunction  (ISO)
colorectal cancer  (ISO)
Colorectal Neoplasms  (ISO)
coronary artery disease  (ISO)
diabetes mellitus  (ISO)
diabetic neuropathy  (ISO)
diabetic retinopathy  (ISO)
disseminated intravascular coagulation  (ISO)
Endotoxemia  (ISO)
Experimental Diabetes Mellitus  (ISO)
Extrahepatic Portal Vein Obstruction  (ISO)
factor VII deficiency  (ISO)
factor X deficiency  (ISO)
familial hyperlipidemia  (ISO)
Glandular and Epithelial Neoplasms  (ISO)
Hematuria  (ISO)
Hemorrhage  (ISO)
hemorrhagic disease  (ISO)
hereditary angioedema  (ISO)
hyperglycemia  (ISO)
hypertension  (ISO)
Hypertriglyceridemia  (ISO)
hypothyroidism  (ISO)
Inherited Blood Coagulation Disease  (ISO)
Insulin Resistance  (ISO)
intermediate coronary syndrome  (ISO)
Intestinal Reperfusion Injury  (ISO)
Intracranial Hemorrhage, Traumatic  (ISO)
Intracranial Hemorrhages  (ISO)
kidney disease  (ISO)
myocardial infarction  (ISO)
obesity  (ISO)
ovarian cancer  (ISO)
Postoperative Complications  (ISO)
proteinuria  (ISO)
prothrombin deficiency  (ISO)
Sepsis  (ISO)
Smoke Inhalation Injury  (ISO)
Subdural Hematoma, Acute  (ISO)
thrombocytopenia  (ISO)
Thromboembolism  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
Venous Thrombosis  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
F7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936472505,751 - 515,375 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
F7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl13113,105,788 - 113,120,685 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl13113,105,788 - 113,120,681 (+)EnsemblGRCh38hg38GRCh38
GRCh3813113,105,773 - 113,120,685 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3713113,760,102 - 113,774,995 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh3713113,760,102 - 113,774,999 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3613112,808,106 - 112,822,996 (+)NCBINCBI36hg18NCBI36
Build 3413112,808,105 - 112,822,346NCBI
Celera1394,585,687 - 94,600,980 (+)NCBI
Cytogenetic Map13q34NCBI
HuRef1394,198,534 - 94,213,700 (+)NCBIHuRef
CHM1_113113,728,824 - 113,743,117 (+)NCBICHM1_1
F7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39813,075,499 - 13,085,809 (+)NCBIGRCm39mm39
GRCm38813,025,506 - 13,035,809 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl813,026,034 - 13,035,809 (+)EnsemblGRCm38mm10GRCm38
MGSCv37813,026,034 - 13,035,809 (+)NCBIGRCm37mm9NCBIm37
MGSCv36813,026,023 - 13,035,786 (+)NCBImm8
Celera813,193,833 - 13,203,593 (+)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map85.73NCBI
F7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21676,489,779 - 76,500,636 (-)NCBI
Rnor_6.0 Ensembl1681,824,111 - 81,834,945 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01681,824,610 - 81,834,923 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01681,309,476 - 81,320,833 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41681,348,678 - 81,358,991 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11681,348,942 - 81,359,256 (-)NCBI
Celera1674,296,307 - 74,306,282 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
F7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955404680,594 - 693,665 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955404685,170 - 692,797 (-)NCBIChiLan1.0ChiLan1.0
F7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.113113,315,868 - 113,329,995 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13113,315,868 - 113,329,995 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01394,246,694 - 94,261,133 (+)NCBIMhudiblu_PPA_v0panPan3
F7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2260,571,822 - 60,597,024 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12260,572,459 - 60,582,743 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
F7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1178,512,158 - 78,518,671 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11178,512,389 - 78,518,668 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21186,217,112 - 86,223,394 (-)NCBISscrofa10.2Sscrofa10.2susScr3
F7
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1391,109,864 - 91,122,707 (+)NCBI
ChlSab1.1 Ensembl391,110,380 - 91,123,327 (+)Ensembl
F7
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624793780,057 - 788,105 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_021730550   ⟹   XP_021586225
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_004936472505,751 - 515,375 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_021586225 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_021586225   ⟸   XM_021730550
- Sequence:
Protein Domains
Gla   Peptidase S1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000025843 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000021387 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000025016 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
  4.10.740.10 UniProtKB/TrEMBL
InterPro Coagulation_fac-like_Gla_dom UniProtKB/TrEMBL
  GLA-like_dom_SF UniProtKB/TrEMBL
  GLA_domain UniProtKB/TrEMBL
  IPR033190 UniProtKB/TrEMBL
  Pept_S1A_FX UniProtKB/TrEMBL
  Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
NCBI Gene F7 ENTREZGENE
PANTHER PTHR24278:SF26 UniProtKB/TrEMBL
Pfam Gla UniProtKB/TrEMBL
  Trypsin UniProtKB/TrEMBL
PIRSF Factor_X UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
  GLABLOOD UniProtKB/TrEMBL
PROSITE GLA_2 UniProtKB/TrEMBL
  TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
SMART GLA UniProtKB/TrEMBL
  Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/TrEMBL
  SSF57630 UniProtKB/TrEMBL
UniProt I3NAJ0_ICTTR UniProtKB/TrEMBL