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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor
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Accession:CHEBI:76838 term browser browse the term
Definition:An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using reduced flavin or flavoprotein as donor (EC 1.14.14.*).
Synonyms:related_synonym: EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitors;   EC 1.14.14.* (oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor;   EC 1.14.14.* (oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitors;   EC 1.14.14.* inhibitor;   EC 1.14.14.* inhibitors


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3,3'-diindolylmethane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
multiple interactions
ISO 3,3'-diindolylmethane results in increased expression of ABCB1 mRNA
[3,3'-diindolylmethane results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; Ketoconazole inhibits the reaction [3,3'-diindolylmethane results in increased expression of ABCB1 mRNA]
CTD PMID:25542144 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Actg1 actin, gamma 1 multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Estradiol results in decreased expression of ACTG1 mRNA] CTD PMID:11179685 NCBI chr10:109,518,429...109,521,288
Ensembl chr 3:75,643,054...75,644,954
Ensembl chr10:75,643,054...75,644,954
JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Lipopolysaccharides results in increased expression of ADGRE1 mRNA] CTD PMID:24162184 NCBI chr 9:9,431,888...9,585,883
Ensembl chr 9:9,431,860...9,585,865
JBrowse link
G Ahr aryl hydrocarbon receptor affects response to substance
affects localization
multiple interactions
ISO
EXP
AHR protein affects the susceptibility to 3,3'-diindolylmethane
3,3'-diindolylmethane affects the localization of AHR protein
3,3'-diindolylmethane binds to and results in decreased activity of AHR protein; 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]
3,3'-diindolylmethane binds to and results in increased activity of AHR protein; 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein]
3,3'-diindolylmethane binds to and results in increased activity of AHR protein; 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTGS2 promoter]]; 3,3'-diindolylmethane promotes the reaction [AHR protein binds to CYP1A1 promoter]; AHR mutant form inhibits the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]; AHR mutant form inhibits the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]]
CTD PMID:8384853 PMID:9771935 PMID:11294972 PMID:16972788 PMID:19056653 PMID:19223575 PMID:20435555 PMID:23583297 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Lipopolysaccharides results in increased expression of AIF1 protein] CTD PMID:24162184 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Ar androgen receptor decreases activity ISO 3,3'-diindolylmethane results in decreased activity of AR protein CTD PMID:30247711 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [ARNT protein binds to CYP1A1 promoter] CTD PMID:16972788 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO 3,3'-diindolylmethane results in increased expression of ATF3 CTD PMID:15670751 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of ATP5F1A mRNA] CTD PMID:11179685 NCBI chr18:74,156,553...74,164,490
Ensembl chr18:74,156,553...74,164,495
JBrowse link
G Bad BCL2-associated agonist of cell death decreases phosphorylation ISO 3,3'-diindolylmethane results in decreased phosphorylation of BAD protein CTD PMID:22290291 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO 3,3'-diindolylmethane results in increased expression of BAX protein CTD PMID:22290291 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions ISO [3,3'-diindolylmethane results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of BBC3 CTD PMID:22290291 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO 3,3'-diindolylmethane promotes the reaction [Paclitaxel results in decreased expression of BCL2 protein]
3,3'-diindolylmethane analog results in decreased expression of BCL2 mRNA
3,3'-diindolylmethane analog results in decreased expression of BCL2 protein; 3,3'-diindolylmethane results in decreased expression of BCL2 protein
CTD PMID:16051428 PMID:16580691 PMID:22290291 PMID:26593444 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression ISO 3,3'-diindolylmethane results in increased expression of BCL2L1 mRNA; 3,3'-diindolylmethane results in increased expression of BCL2L1 protein CTD PMID:18025290 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l10 BCL2 like 10 increases expression ISO 3,3'-diindolylmethane results in increased expression of BCL2L10 mRNA CTD PMID:22514694 NCBI chr 8:82,288,705...82,294,750
Ensembl chr 8:82,288,705...82,294,744
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO 3,3'-diindolylmethane results in decreased expression of BIRC5 protein CTD PMID:22290291 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Brd2 bromodomain containing 2 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of BRD2 mRNA] CTD PMID:11179685 NCBI chr20:3,910,555...3,921,074
Ensembl chr20:3,910,555...3,917,426
Ensembl chr20:3,910,555...3,917,426
JBrowse link
G Calm2 calmodulin 2 multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Estradiol results in decreased expression of CALM2 mRNA] CTD PMID:11179685 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
JBrowse link
G Casp3 caspase 3 increases activity ISO 3,3'-diindolylmethane results in increased activity of CASP3 protein CTD PMID:21820497 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ccn1 cellular communication network factor 1 affects methylation ISO 3,3'-diindolylmethane affects the methylation of CCN1 promoter CTD PMID:24466240 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO 3,3'-diindolylmethane results in decreased expression of CCNB1 CTD PMID:22290291 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
ISO 3,3'-diindolylmethane analog results in decreased expression of CCND1 protein; 3,3'-diindolylmethane results in decreased expression of CCND1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [3,3'-diindolylmethane analog results in decreased expression of CCND1 protein]
CTD PMID:16051428 PMID:22290291 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO 3,3'-diindolylmethane results in decreased expression of CCND3 protein CTD PMID:22514694 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 affects methylation ISO 3,3'-diindolylmethane affects the methylation of CCR4 promoter CTD PMID:24466240 NCBI chr 8:122,530,152...122,535,959
Ensembl chr 8:122,530,624...122,532,070
JBrowse link
G Cd40lg CD40 ligand increases expression ISO 3,3'-diindolylmethane results in increased expression of CD40LG mRNA CTD PMID:22514694 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cd69 Cd69 molecule multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased expression of CD69 protein] CTD PMID:24200994 NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084
JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO 3,3'-diindolylmethane results in decreased expression of CDC25C CTD PMID:22290291 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in decreased expression of CDH1 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of CDH1 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in decreased expression of CDH1 protein] CTD PMID:28844962 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh11 cadherin 11 decreases expression ISO 3,3'-diindolylmethane results in decreased expression of CDH11 protein CTD PMID:18025290 NCBI chr19:2,391,181...2,551,245
Ensembl chr19:2,393,059...2,551,245
JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of CDH2 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of CDH2 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of CDH2 protein] CTD PMID:28844962 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
decreases activity
ISO 3,3'-diindolylmethane promotes the reaction [CDK2 protein binds to CDKN1A protein]
3,3'-diindolylmethane results in decreased activity of CDK2 protein
CTD PMID:15611077 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO 3,3'-diindolylmethane results in decreased expression of CDK4 protein CTD PMID:22514694 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk6 cyclin-dependent kinase 6 decreases expression ISO 3,3'-diindolylmethane results in decreased expression of CDK6 protein CTD PMID:22290291 PMID:22514694 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO 3,3'-diindolylmethane promotes the reaction [CDK2 protein binds to CDKN1A protein]
3,3'-diindolylmethane results in increased expression of CDKN1A mRNA; 3,3'-diindolylmethane results in increased expression of CDKN1A protein
CTD PMID:12203118 PMID:15611077 PMID:18025290 PMID:22290291 PMID:22495798 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO 3,3'-diindolylmethane results in increased expression of CDKN1B protein CTD PMID:22290291 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D increases expression ISO 3,3'-diindolylmethane results in increased expression of CDKN2D protein CTD PMID:22290291
G Chuk component of inhibitor of nuclear factor kappa B kinase complex decreases phosphorylation ISO 3,3'-diindolylmethane results in decreased phosphorylation of CHUK protein CTD PMID:22290291 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Estradiol results in decreased expression of CKS1B mRNA] CTD PMID:11179685 NCBI chr 2:188,740,564...188,745,144
Ensembl chr 2:188,740,573...188,745,144
JBrowse link
G Ctsb cathepsin B multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of CTSB protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of CTSB protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of CTSB protein] CTD PMID:28844962 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsd cathepsin D multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of CTSD protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of CTSD protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of CTSD protein] CTD PMID:28844962 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 affects methylation
multiple interactions
ISO 3,3'-diindolylmethane affects the methylation of CXCR4 promoter
3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of CXCR4 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of CXCR4 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of CXCR4 protein]
CTD PMID:24466240 PMID:28844962 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO 3,3'-diindolylmethane analog affects the localization of and results in increased expression of CYCS protein CTD PMID:16051428 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression ISO 3,3'-diindolylmethane analog results in increased expression of CYP19A1 mRNA; 3,3'-diindolylmethane results in increased expression of CYP19A1 mRNA CTD PMID:11294972 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases activity
increases expression
decreases activity
ISO
EXP
3,3'-diindolylmethane promotes the reaction [AHR protein binds to CYP1A1 promoter]; 3,3'-diindolylmethane promotes the reaction [ARNT protein binds to CYP1A1 promoter]; 3,3'-diindolylmethane promotes the reaction [ESR1 protein binds to CYP1A1 promoter]; [3,3'-diindolylmethane results in increased expression of CYP1A1 mRNA] which results in increased abundance of aflatoxin B1-DNA adduct
3,3'-diindolylmethane analog results in increased activity of CYP1A1 protein; 3,3'-diindolylmethane results in increased activity of CYP1A1 protein
3,3'-diindolylmethane results in increased expression of CYP1A1 protein
3,3'-diindolylmethane analog results in increased expression of CYP1A1 mRNA; 3,3'-diindolylmethane results in increased expression of CYP1A1 mRNA; 3,3'-diindolylmethane results in increased expression of CYP1A1 protein
3,3'-diindolylmethane results in decreased activity of CYP1A1 protein
CTD PMID:8384853 PMID:9771935 PMID:11179685 PMID:11294972 PMID:11597580 PMID:15672752 PMID:16972788 PMID:19770484 PMID:22495798 PMID:23583297 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
decreases activity
increases oxidation
ISO
EXP
[3,3'-diindolylmethane results in increased expression of CYP1A2 mRNA] which results in increased abundance of aflatoxin B1-DNA adduct; Quercetin inhibits the reaction [CYP1A2 protein results in increased oxidation of 3,3'-diindolylmethane]; resveratrol inhibits the reaction [CYP1A2 protein results in increased oxidation of 3,3'-diindolylmethane]
3,3'-diindolylmethane results in increased expression of CYP1A2 protein
3,3'-diindolylmethane results in increased expression of CYP1A2 mRNA; 3,3'-diindolylmethane results in increased expression of CYP1A2 protein
3,3'-diindolylmethane results in decreased activity of CYP1A2 protein
CTD PMID:8384853 PMID:15672752 PMID:16544949 PMID:19770484 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO 3,3'-diindolylmethane analog results in increased expression of CYP1B1 mRNA; 3,3'-diindolylmethane results in increased expression of CYP1B1 mRNA CTD PMID:11294972 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP 3,3'-diindolylmethane results in increased expression of CYP2B1 protein CTD PMID:8384853 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP 3,3'-diindolylmethane results in increased expression of CYP2B2 protein CTD PMID:8384853 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO 3,3'-diindolylmethane results in increased expression of DDIT3 protein CTD PMID:22290291 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression ISO 3,3'-diindolylmethane results in decreased expression of DNMT1 mRNA CTD PMID:24466240 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression ISO 3,3'-diindolylmethane results in decreased expression of DNMT3B mRNA CTD PMID:24466240 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of EEF1G mRNA] CTD PMID:11179685 NCBI chr 1:225,163,391...225,173,997
Ensembl chr 1:225,163,391...225,173,995
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Paclitaxel results in decreased phosphorylation of and results in decreased activity of ERBB2 protein]; 3,3'-diindolylmethane results in decreased phosphorylation of and results in decreased activity of ERBB2 protein CTD PMID:16580691 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases expression
ISO 3,3'-diindolylmethane binds to and results in increased activity of ESR1 protein; 3,3'-diindolylmethane promotes the reaction [ESR1 protein binds to CYP1A1 promoter]; 3,3'-diindolylmethane promotes the reaction [ESR1 protein binds to TFF1 promoter]; ESR1 mutant form promotes the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]
3,3'-diindolylmethane results in decreased expression of ESR1
CTD PMID:16972788 PMID:19223575 PMID:23583297 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases expression
ISO 3,3'-diindolylmethane promotes the reaction [ESR2 protein binds to KRT19 promoter]; 3,3'-diindolylmethane promotes the reaction [ESR2 protein binds to TMEM121B promoter]; ESR2 affects the reaction [3,3'-diindolylmethane promotes the reaction [NCOA2 protein binds to KRT19 promoter]]; ESR2 affects the reaction [3,3'-diindolylmethane results in increased expression of KRT19 mRNA]; ESR2 affects the reaction [3,3'-diindolylmethane results in increased expression of TMEM121B mRNA]; Raloxifene Hydrochloride inhibits the reaction [3,3'-diindolylmethane results in increased expression of ESR2 mRNA]; Tamoxifen inhibits the reaction [3,3'-diindolylmethane results in increased expression of ESR2 mRNA] CTD PMID:20160136 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Fau FAU, ubiquitin like and ribosomal protein S30 fusion multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Estradiol results in decreased expression of FAU mRNA] CTD PMID:11179685 NCBI chr 1:221,420,312...221,421,827
Ensembl chr 1:221,420,271...221,421,842
Ensembl chr 6:221,420,271...221,421,842
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO 3,3'-diindolylmethane results in increased expression of GDF15 mRNA CTD PMID:15670751 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gnas GNAS complex locus multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of GNAS mRNA] CTD PMID:11179685 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 increases expression ISO 3,3'-diindolylmethane results in increased expression of GREB1 mRNA CTD PMID:23583297 NCBI chr 6:41,932,941...42,002,770
Ensembl chr 6:41,932,244...42,002,819
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation ISO 3,3'-diindolylmethane results in decreased phosphorylation of GSK3B protein CTD PMID:22290291 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases expression
multiple interactions
ISO 3,3'-diindolylmethane results in decreased expression of GSTM1 mRNA
[3,3'-diindolylmethane results in decreased expression of GSTM1 mRNA] which results in increased abundance of aflatoxin B1-DNA adduct
CTD PMID:19770484 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G H3f3a H3.3 histone A multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of H3-3A mRNA] CTD PMID:11179685 NCBI chr13:99,091,246...99,102,828
Ensembl chr13:99,091,763...99,101,208
JBrowse link
G Hdac1 histone deacetylase 1 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased expression of HDAC1 mRNA] CTD PMID:24200994 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac10 histone deacetylase 10 multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [enterotoxin B, staphylococcal results in decreased expression of HDAC10 mRNA] CTD PMID:24200994 NCBI chr 7:130,102,335...130,109,036
Ensembl chr 7:130,102,347...130,107,437
JBrowse link
G Hdac2 histone deacetylase 2 decreases expression
multiple interactions
ISO 3,3'-diindolylmethane results in decreased expression of HDAC2 protein
3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased expression of HDAC2 mRNA]
CTD PMID:22800507 PMID:24200994 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hdac5 histone deacetylase 5 multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [enterotoxin B, staphylococcal results in decreased expression of HDAC5 mRNA] CTD PMID:24200994 NCBI chr10:90,140,183...90,169,853
Ensembl chr10:90,140,183...90,151,042
JBrowse link
G Hdac8 histone deacetylase 8 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased expression of HDAC8 mRNA] CTD PMID:24200994 NCBI chr  X:72,163,777...72,370,058
Ensembl chr  X:72,163,777...72,370,044
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]; AHR mutant form inhibits the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]; ESR1 mutant form promotes the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]] CTD PMID:23583297 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hrk harakiri, BCL2 interacting protein increases expression ISO 3,3'-diindolylmethane results in increased expression of HRK mRNA CTD PMID:22514694 NCBI chr12:44,008,879...44,029,211 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression
multiple interactions
ISO 3,3'-diindolylmethane analog results in decreased expression of HSPA5 protein
3,3'-diindolylmethane analog promotes the reaction [HSPA5 protein affects the expression of and affects the activity of MMP9 protein]
CTD PMID:25794856 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of HSPB1 mRNA] CTD PMID:11179685 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Ifng interferon gamma multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased secretion of IFNG protein] CTD PMID:24200994 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il2 interleukin 2 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased secretion of IL2 protein] CTD PMID:24200994 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO 3,3'-diindolylmethane results in increased expression of IL6 mRNA
3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased secretion of IL6 protein]
CTD PMID:18025290 PMID:24200994 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Kdr kinase insert domain receptor decreases expression ISO 3,3'-diindolylmethane analog results in decreased expression of KDR protein CTD PMID:25794856 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Klf10 Kruppel-like factor 10 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of KLF10 mRNA] CTD PMID:11179685 NCBI chr 7:77,156,010...77,162,096
Ensembl chr 7:77,156,006...77,162,148
JBrowse link
G Krt18 keratin 18 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of KRT18 mRNA] CTD PMID:11179685 NCBI chr 7:143,629,455...143,633,131
Ensembl chr 7:143,629,455...143,633,131
JBrowse link
G Krt19 keratin 19 multiple interactions
increases expression
ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of KRT19 mRNA]; 3,3'-diindolylmethane promotes the reaction [ESR2 protein binds to KRT19 promoter]; 3,3'-diindolylmethane promotes the reaction [NCOA2 protein binds to KRT19 promoter]; ESR2 affects the reaction [3,3'-diindolylmethane promotes the reaction [NCOA2 protein binds to KRT19 promoter]]; ESR2 affects the reaction [3,3'-diindolylmethane results in increased expression of KRT19 mRNA]; NCOA2 mutant form inhibits the reaction [3,3'-diindolylmethane results in increased expression of KRT19 mRNA] CTD PMID:11179685 PMID:20160136 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561
JBrowse link
G Magea9 MAGE family member A9 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of MAGEA9 mRNA] CTD PMID:11179685 NCBI chr  X:147,491,247...147,496,650
Ensembl chr  X:147,493,880...147,496,649
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [3,3'-diindolylmethane results in decreased phosphorylation of MAPK1 protein]; 3,3'-diindolylmethane promotes the reaction [Paclitaxel results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]; 3,3'-diindolylmethane results in decreased phosphorylation of and results in decreased activity of MAPK1 protein CTD PMID:16580691 PMID:22290291 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation
multiple interactions
ISO 3,3'-diindolylmethane results in decreased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [3,3'-diindolylmethane results in decreased phosphorylation of MAPK3 protein]; 3,3'-diindolylmethane promotes the reaction [Paclitaxel results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]; 3,3'-diindolylmethane results in decreased phosphorylation of and results in decreased activity of MAPK3 protein
CTD PMID:16580691 PMID:22290291 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mdm2 MDM2 proto-oncogene decreases expression ISO 3,3'-diindolylmethane analog results in decreased expression of MDM2 mRNA CTD PMID:26593444 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of MMP2 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of MMP2 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of MMP2 protein] CTD PMID:28844962 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO 3,3'-diindolylmethane analog promotes the reaction [HSPA5 protein affects the expression of and affects the activity of MMP9 protein]; 3,3'-diindolylmethane analog results in decreased expression of and results in decreased activity of MMP9 protein; 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of MMP9 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of MMP9 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of MMP9 protein] CTD PMID:25794856 PMID:28844962 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of COX2 mRNA] CTD PMID:11179685 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Myb MYB proto-oncogene, transcription factor decreases expression ISO 3,3'-diindolylmethane analog results in decreased expression of MYB mRNA CTD PMID:26593444 NCBI chr 1:16,658,178...16,690,135
Ensembl chr 1:16,659,442...16,687,817
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO 3,3'-diindolylmethane results in decreased expression of MYC protein
3,3'-diindolylmethane analog results in decreased expression of MYC mRNA
CTD PMID:22290291 PMID:26593444 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myl6 myosin light chain 6 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of MYL6 mRNA] CTD PMID:11179685 NCBI chr 7:2,906,137...2,909,193
Ensembl chr 7:2,906,137...2,909,179
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [NCOA2 protein binds to KRT19 promoter]; ESR2 affects the reaction [3,3'-diindolylmethane promotes the reaction [NCOA2 protein binds to KRT19 promoter]]; NCOA2 mutant form inhibits the reaction [3,3'-diindolylmethane results in increased expression of KRT19 mRNA]; NCOA2 mutant form inhibits the reaction [3,3'-diindolylmethane results in increased expression of TMEM121B mRNA] CTD PMID:20160136 NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression
multiple interactions
ISO 3,3'-diindolylmethane results in increased expression of NFE2L2 mRNA; 3,3'-diindolylmethane results in increased expression of NFE2L2 protein
sulforaphane promotes the reaction [3,3'-diindolylmethane results in increased expression of NFE2L2 mRNA]; sulforaphane promotes the reaction [3,3'-diindolylmethane results in increased expression of NFE2L2 protein]
CTD PMID:23583297 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] CTD PMID:24162184 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
ISO 3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]; AHR mutant form inhibits the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]]
3,3'-diindolylmethane results in increased expression of NQO1 mRNA
CTD PMID:15672752 PMID:22495798 PMID:23583297 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions
ISO 3,3'-diindolylmethane results in increased activity of NR1I2 protein
[3,3'-diindolylmethane results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; [3,3'-diindolylmethane results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA
CTD PMID:25542144 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nup133 nucleoporin 133 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of NUP133 mRNA] CTD PMID:11179685 NCBI chr19:56,681,965...56,731,404
Ensembl chr19:56,681,979...56,731,372
JBrowse link
G Papola poly (A) polymerase alpha multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of PAPOLA mRNA] CTD PMID:11179685 NCBI chr 6:129,609,068...129,662,002
Ensembl chr 6:129,609,074...129,661,531
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [3,3'-diindolylmethane co-treated with Paclitaxel] results in increased cleavage of and results in increased activity of PARP1 protein CTD PMID:16580691 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Plau plasminogen activator, urokinase increases expression ISO 3,3'-diindolylmethane results in increased expression of PLAU mRNA CTD PMID:18025290 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 multiple interactions ISO [3,3'-diindolylmethane results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of PMAIP1 CTD PMID:22290291 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression
ISO 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTGS2 promoter]]; 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; 3,3'-diindolylmethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 protein]
3,3'-diindolylmethane inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]
3,3'-diindolylmethane results in decreased expression of PTGS2 mRNA; 3,3'-diindolylmethane results in decreased expression of PTGS2 protein
CTD PMID:19056653 PMID:22290291 PMID:24162184 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases expression ISO 3,3'-diindolylmethane results in decreased expression of RELA protein CTD PMID:22290291 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ribc1 RIB43A domain with coiled-coils 1 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of RIBC1 mRNA] CTD PMID:11179685 NCBI chr  X:21,699,361...21,711,335
Ensembl chr  X:21,698,011...21,710,678
JBrowse link
G Rpl10 ribosomal protein L10 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of RPL10 mRNA]; 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of RPL10 mRNA] CTD PMID:11179685 NCBI chr  X:156,438,251...156,440,461
Ensembl chr  X:156,438,251...156,440,461
JBrowse link
G Rpl13a ribosomal protein L13A multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of RPL13A mRNA] CTD PMID:11179685 NCBI chr 1:101,120,325...101,123,401
Ensembl chr 1:101,120,325...101,123,402
JBrowse link
G Rpl31 ribosomal protein L31 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of RPL31 mRNA] CTD PMID:11179685 NCBI chr 9:46,086,959...46,090,444
Ensembl chr 9:46,086,984...46,090,997
JBrowse link
G Rpl41 ribosomal protein L41 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of RPL41 mRNA] CTD PMID:11179685 NCBI chr 7:2,972,897...2,973,977
Ensembl chr 7:2,972,900...2,973,977
JBrowse link
G Rpl7 ribosomal protein L7 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of RPL7 mRNA] CTD PMID:11179685 NCBI chr 5:2,633,517...2,636,525
Ensembl chr 5:2,632,712...2,640,021
JBrowse link
G Rplp0 ribosomal protein lateral stalk subunit P0 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of RPLP0 mRNA] CTD PMID:11179685 NCBI chr12:46,791,528...46,794,797
Ensembl chr12:46,791,528...46,794,797
JBrowse link
G Rps15a ribosomal protein S15a multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of RPS15A mRNA] CTD PMID:11179685 NCBI chr 1:187,759,865...187,766,734
Ensembl chr 1:187,759,480...187,766,709
JBrowse link
G Rps17 ribosomal protein S17 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of RPS17 mRNA] CTD PMID:11179685 NCBI chr 1:143,167,329...143,169,915
Ensembl chr 1:143,167,362...143,169,657
JBrowse link
G Rps3 ribosomal protein S3 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of RPS3 mRNA] CTD PMID:11179685 NCBI chr 1:164,435,868...164,441,167
Ensembl chr 1:164,435,878...164,441,167
JBrowse link
G Rps4x ribosomal protein S4, X-linked multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of RPS4X mRNA] CTD PMID:11179685 NCBI chr  X:72,074,108...72,078,551
Ensembl chr  X:72,074,108...72,078,551
Ensembl chr 4:72,074,108...72,078,551
JBrowse link
G Rps6 ribosomal protein S6 multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of RPS6 mRNA] CTD PMID:11179685 NCBI chr 5:105,197,821...105,200,681
Ensembl chr 5:105,197,857...105,200,148
Ensembl chr 5:105,197,857...105,200,148
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of SNAI1 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of SNAI1 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of SNAI1 protein] CTD PMID:28844962 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Snai2 snail family transcriptional repressor 2 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of SNAI2 protein]; 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of SNAI2 protein]; 3,3'-diindolylmethane inhibits the reaction [Triclosan results in increased expression of SNAI2 protein] CTD PMID:28844962 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Tff1 trefoil factor 1 multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [ESR1 protein binds to TFF1 promoter] CTD PMID:16972788 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 affects methylation ISO 3,3'-diindolylmethane affects the methylation of TGFBR1 promoter CTD PMID:24466240 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO 3,3'-diindolylmethane analog results in increased expression of TIMP1 protein CTD PMID:25794856 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tmem121b transmembrane protein 121B multiple interactions
increases expression
ISO 3,3'-diindolylmethane promotes the reaction [ESR2 protein binds to TMEM121B promoter]; ESR2 affects the reaction [3,3'-diindolylmethane results in increased expression of TMEM121B mRNA]; NCOA2 mutant form inhibits the reaction [3,3'-diindolylmethane results in increased expression of TMEM121B mRNA] CTD PMID:20160136 NCBI chr 4:153,018,163...153,029,673
Ensembl chr 4:153,026,411...153,028,129
JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions
ISO 3,3'-diindolylmethane results in decreased expression of TNF mRNA
3,3'-diindolylmethane inhibits the reaction [enterotoxin B, staphylococcal results in increased secretion of TNF protein]
CTD PMID:22514694 PMID:24200994 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression ISO 3,3'-diindolylmethane results in increased expression of TNFRSF1A mRNA CTD PMID:22514694 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 decreases expression ISO 3,3'-diindolylmethane results in decreased expression of TNFRSF25 mRNA CTD PMID:22514694 NCBI chr 5:169,288,419...169,293,137
Ensembl chr 5:169,288,871...169,293,137
JBrowse link
G Tnfsf8 TNF superfamily member 8 increases expression ISO 3,3'-diindolylmethane results in increased expression of TNFSF8 mRNA CTD PMID:22514694 NCBI chr 5:79,664,779...79,691,547
Ensembl chr 5:79,664,765...79,691,258
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO 3,3'-diindolylmethane results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein; [3,3'-diindolylmethane results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of BBC3; [3,3'-diindolylmethane results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of PMAIP1; wortmannin inhibits the reaction [3,3'-diindolylmethane results in increased phosphorylation of TP53 protein] CTD PMID:22290291 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Traf4 Tnf receptor associated factor 4 decreases expression ISO 3,3'-diindolylmethane results in decreased expression of TRAF4 mRNA CTD PMID:22514694 NCBI chr10:65,418,688...65,424,802
Ensembl chr10:65,418,700...65,424,802
JBrowse link
G Tyms thymidylate synthetase multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of TYMS mRNA] CTD PMID:11179685 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link
G Ubb ubiquitin B multiple interactions ISO 3,3'-diindolylmethane promotes the reaction [Estradiol results in increased expression of UBB mRNA] CTD PMID:11179685 NCBI chr10:48,880,231...48,881,896
Ensembl chr10:48,881,049...48,881,881
JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO 3,3'-diindolylmethane results in decreased expression of XIAP protein CTD PMID:22290291 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link
G Xrcc6 X-ray repair cross complementing 6 multiple interactions ISO 3,3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of XRCC6 mRNA] CTD PMID:11179685 NCBI chr 7:123,259,881...123,280,613
Ensembl chr 7:123,259,761...123,280,612
JBrowse link
5'-hydroxyomeprazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP 5-hydroxymethylomeprazole results in increased expression of CYP1A1 protein CTD PMID:10103034 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
alpha-naphthoflavone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 multiple interactions EXP [alpha-naphthoflavone co-treated with Methylcholanthrene] results in decreased acetylation of ADAMTS1 promoter; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of ADAMTS1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of ADAMTS1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of ADAMTS1 promoter] CTD PMID:29094188 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Ahr aryl hydrocarbon receptor affects binding
decreases activity
multiple interactions
ISO
EXP
[alpha-naphthoflavone binds to AHR protein] which binds to ESR1 protein; [alpha-naphthoflavone binds to AHR protein] which binds to ESRRA protein; [alpha-naphthoflavone binds to AHR protein] which binds to NR2F1 protein; alpha-naphthoflavone binds to AHR protein
alpha-naphthoflavone results in decreased activity of AHR protein
[alpha-naphthoflavone results in decreased activity of AHR protein] which results in decreased expression of CYP1A1 mRNA; AHR gene mutant form inhibits the reaction [alpha-naphthoflavone results in increased expression of IGFBP4 protein]; AHR protein promotes the reaction [alpha-naphthoflavone results in decreased expression of CDH13 mRNA]; alpha-naphthoflavone binds to and results in decreased activity of AHR protein; alpha-naphthoflavone binds to and results in increased activity of AHR protein; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [hydroquinone results in increased expression of AHR protein]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to BAX promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CASP9 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CDK2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to DNAJB6 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to HES1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to ICAM1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to IGF2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to JAG1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to SP1 promoter]]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased localization of and results in increased activity of AHR protein]; alpha-naphthoflavone promotes the reaction [beta-Naphthoflavone results in decreased expression of AHR mRNA]
[alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of IL10 protein]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] results in decreased susceptibility to [SB 203580 results in increased expression of CYP1A1]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] which results in decreased susceptibility to Benzo(a)pyrene; alpha-naphthoflavone binds to and results in decreased activity of AHR protein; alpha-naphthoflavone binds to and results in increased activity of AHR protein; alpha-naphthoflavone inhibits the reaction [AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased localization of and results in increased activity of AHR protein]
[alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of and results in increased activity of MAPK1 protein]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of and results in increased activity of MAPK3 protein]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of and results in increased activity of STAT5B protein]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Skatole results in increased expression of CYP1A1 mRNA]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Skatole results in increased expression of CYP2F1 mRNA]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of FLG mRNA]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] which results in decreased susceptibility to Hexachlorobenzene; [alpha-naphthoflavone results in decreased activity of AHR protein] inhibits the reaction [Tetrachlorodibenzodioxin results in increased abundance of Reactive Oxygen Species]; alpha-naphthoflavone analog inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; alpha-naphthoflavone analog results in increased activity of [AHR protein binds to ARNT protein]; alpha-naphthoflavone binds to and results in decreased activity of AHR protein; alpha-naphthoflavone inhibits the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 enhancer]; alpha-naphthoflavone inhibits the reaction [[AHR protein binds to ARNT protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[Benzo(a)pyrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[benzo(k)fluoranthene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[chrysene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[Oxygen deficiency co-treated with Tetrachlorodibenzodioxin] results in decreased stability of AHR protein]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased activity of BRCA1 protein]; alpha-naphthoflavone inhibits the reaction [AHR promotes the reaction [Tetrachlorodibenzodioxin results in decreased uptake of Glucose]]; alpha-naphthoflavone inhibits the reaction [AHR protein binds to and results in increased metabolism of Benzo(a)pyrene]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased localization of and results in increased activity of AHR protein]; alpha-naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]
CTD PMID:1329656 PMID:7669069 PMID:8390116 PMID:8738555 PMID:9006915 PMID:10593590 PMID:10620335 PMID:11165043 PMID:11516172 PMID:11577022 PMID:11768231 PMID:12051995 PMID:12093619 PMID:12111005 PMID:12559965 PMID:12644593 PMID:12799773 PMID:14993811 PMID:15019843 PMID:15041469 PMID:15364539 PMID:15459018 PMID:15797623 PMID:16054781 PMID:16359657 PMID:17669606 PMID:17681673 PMID:18072750 PMID:18259752 PMID:19828881 PMID:20187624 PMID:20634293 PMID:21127131 PMID:21205633 PMID:21732638 PMID:21835898 PMID:22975028 PMID:23639626 PMID:24161567 PMID:26519956 PMID:29094188 PMID:29935983 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases methylation
EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of AKT1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of AKT1 mRNA]
alpha-naphthoflavone results in increased methylation of AKT1 promoter
CTD PMID:29094188 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Ar androgen receptor multiple interactions
increases expression
ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased expression of AR protein]; alpha-naphthoflavone inhibits the reaction [Particulate Matter analog inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]]; alpha-naphthoflavone inhibits the reaction [Vehicle Emissions analog inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]]; bicalutamide inhibits the reaction [alpha-naphthoflavone inhibits the reaction [Particulate Matter analog inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]]]; bicalutamide inhibits the reaction [alpha-naphthoflavone inhibits the reaction [Vehicle Emissions analog inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]]]
alpha-naphthoflavone results in increased expression of AR protein
CTD PMID:12970580 PMID:15041469 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO alpha-naphthoflavone analog results in increased activity of [AHR protein binds to ARNT protein]; alpha-naphthoflavone inhibits the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 enhancer]; alpha-naphthoflavone inhibits the reaction [[AHR protein binds to ARNT protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]
ARNT protein affects the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]
CTD PMID:11768231 PMID:21127131 PMID:30508555 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP
alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in increased expression of BAX mRNA]
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to BAX promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of BAX mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of BAX promoter]
CTD PMID:20562217 PMID:29094188 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bmp15 bone morphogenetic protein 15 multiple interactions EXP [Methylcholanthrene co-treated with alpha-naphthoflavone] results in increased expression of BMP15 mRNA CTD PMID:29094188 NCBI chr  X:17,016,831...17,021,894
Ensembl chr  X:17,016,778...17,023,418
JBrowse link
G Bpgm bisphosphoglycerate mutase multiple interactions
increases expression
ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of BPGM mRNA]
alpha-naphthoflavone results in increased expression of BPGM mRNA
CTD PMID:23152189 NCBI chr 4:61,912,210...61,940,697
Ensembl chr 4:61,912,210...61,940,696
JBrowse link
G Brca1 BRCA1, DNA repair associated multiple interactions ISO alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased activity of BRCA1 protein]; alpha-naphthoflavone inhibits the reaction [Estradiol results in increased expression of BRCA1 mRNA] CTD PMID:16489025 PMID:18259752 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Calr calreticulin multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CALR mRNA] CTD PMID:29094188 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Casp12 caspase 12 increases cleavage ISO alpha-naphthoflavone results in increased cleavage of CASP12 protein CTD PMID:30508555 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage
decreases activity
ISO
EXP
alpha-naphthoflavone results in increased activity of CASP3 protein
alpha-naphthoflavone results in increased cleavage of CASP3 protein
alpha-naphthoflavone results in decreased activity of CASP3 protein
CTD PMID:15710172 PMID:18334599 PMID:30508555 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases activity ISO alpha-naphthoflavone results in increased activity of CASP8 protein CTD PMID:18334599 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions
ISO
EXP
alpha-naphthoflavone results in increased activity of CASP9 protein
[alpha-naphthoflavone co-treated with Methylcholanthrene] results in decreased acetylation of CASP9 promoter; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CASP9 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CASP9 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of CASP9 promoter]
CTD PMID:18334599 PMID:29094188 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased activity of CAT protein] CTD PMID:20600218 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl1 C-C motif chemokine ligand 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CCL1] CTD PMID:16679317 NCBI chr10:69,534,976...69,537,836
Ensembl chr10:69,534,933...69,537,882
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
increases expression
multiple interactions
ISO alpha-naphthoflavone results in decreased expression of CCL2 mRNA
alpha-naphthoflavone results in increased expression of CCL2 mRNA
alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CCL2 mRNA]
CTD PMID:22262711 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Plant Extracts results in decreased expression of CCNB1 mRNA] CTD PMID:25051199 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Cd9 CD9 molecule multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of CD9 mRNA] CTD PMID:29094188 NCBI chr 4:157,977,163...158,010,091
Ensembl chr 4:157,977,162...158,010,166
JBrowse link
G Cdc25c cell division cycle 25C multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Plant Extracts results in decreased expression of CDC25C mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of CDC25C protein] CTD PMID:22266097 PMID:25051199 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Cdh13 cadherin 13 multiple interactions EXP AHR protein promotes the reaction [alpha-naphthoflavone results in decreased expression of CDH13 mRNA]; alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDH13 mRNA]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased expression of CDH13 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDH13 mRNA] CTD PMID:12559965 NCBI chr19:50,848,793...51,971,618
Ensembl chr19:50,848,736...51,972,103
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of CDK1 protein] CTD PMID:22266097 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
decreases methylation
EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CDK2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased methylation of CDK2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of CDK2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CDK2 mRNA]
alpha-naphthoflavone results in decreased methylation of CDK2 promoter
CTD PMID:29094188 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene promotes the reaction [eupatorin-5-methyl ether results in increased expression of CDKN1A protein]]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CDKN1A mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDKN1A protein] CTD PMID:21887816 PMID:22266097 PMID:23994263 PMID:24361490 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDKN1B protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CDKN1B protein] CTD PMID:15157999 PMID:22266097 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta multiple interactions ISO alpha-naphthoflavone promotes the reaction [Particulate Matter results in increased expression of CEBPD mRNA] CTD PMID:21652769 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of CSF2 mRNA] CTD PMID:20801209 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Ctsd cathepsin D multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CTSD mRNA]] CTD PMID:11165043 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cygb cytoglobin multiple interactions ISO alpha-naphthoflavone inhibits the reaction [2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole results in increased expression of CYGB mRNA] CTD PMID:25781201 NCBI chr10:105,618,325...105,628,091
Ensembl chr10:105,618,326...105,628,091
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 multiple interactions
increases expression
ISO alpha-naphthoflavone promotes the reaction [CYP11B1 protein results in increased chemical synthesis of Hydrocortisone]
alpha-naphthoflavone results in increased expression of CYP11B1 mRNA
CTD PMID:22172629 NCBI chr 7:116,248,759...116,255,205
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO alpha-naphthoflavone results in decreased expression of CYP17A1 mRNA CTD PMID:24875446 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO [alpha-naphthoflavone results in decreased activity of CYP19A1 protein] which results in decreased susceptibility to o,p'-DDT; alpha-naphthoflavone binds to and results in decreased activity of CYP19A1 protein; alpha-naphthoflavone inhibits the reaction [Aflatoxin B1 results in increased expression of CYP19A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYP19A1 protein]
alpha-naphthoflavone results in increased expression of CYP19A1 protein
CTD PMID:9435150 PMID:20678559 PMID:20823264 PMID:21296134 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
affects binding
increases expression
multiple interactions
decreases activity
ISO
EXP
alpha-naphthoflavone results in increased activity of CYP1A1 protein
CYP1A1 protein binds to alpha-naphthoflavone
alpha-naphthoflavone results in increased expression of CYP1A1 mRNA
alpha-naphthoflavone analog results in increased expression of CYP1A1 mRNA; alpha-naphthoflavone results in increased expression of CYP1A1 mRNA; alpha-naphthoflavone results in increased expression of CYP1A1 protein
[alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Skatole results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [[3,4,5,3',4'-pentachlorobiphenyl co-treated with Benzo(a)pyrene] results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 enhancer]; alpha-naphthoflavone inhibits the reaction [[AHR protein binds to ARNT protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[Benzo(a)pyrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[benzo(k)fluoranthene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[chrysene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] which results in increased metabolism of Benzo(a)pyrene]; alpha-naphthoflavone inhibits the reaction [afimoxifene results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Calcitriol promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]]; alpha-naphthoflavone inhibits the reaction [Carbaryl results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Resveratrol results in increased expression of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [STO 609 results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Vehicle Emissions results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]
alpha-naphthoflavone results in decreased activity of CYP1A1 protein
[alpha-naphthoflavone results in decreased activity of AHR protein] which results in decreased expression of CYP1A1 mRNA; [alpha-naphthoflavone results in decreased activity of CYP1A1 protein] inhibits the reaction [Vinyl Compounds analog results in decreased susceptibility to sodium arsenite]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of CYP1A1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of CYP1A1 promoter]; alpha-naphthoflavone inhibits the reaction [norisoboldine results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]; alpha-naphthoflavone promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]
[[alpha-naphthoflavone results in decreased activity of CYP1A2 protein] co-treated with [alpha-naphthoflavone results in decreased activity of CYP1A1 protein]] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]; [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] results in decreased susceptibility to [SB 203580 results in increased expression of CYP1A1]; alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; SRC protein affects the reaction [alpha-naphthoflavone results in increased expression of CYP1A1 mRNA]; SU 6656 inhibits the reaction [alpha-naphthoflavone results in increased expression of CYP1A1 mRNA]
alpha-naphthoflavone analog results in increased activity of CYP1A1 protein
CTD PMID:1329656 PMID:6477826 PMID:7669069 PMID:8390116 PMID:8637871 PMID:9169082 PMID:10496962 PMID:11339718 PMID:11516172 PMID:11768231 PMID:12051995 PMID:12093619 PMID:12111005 PMID:12799773 PMID:12859983 PMID:14993811 PMID:15075337 PMID:15276085 PMID:15306208 PMID:15385644 PMID:15456928 PMID:15698582 PMID:15766918 PMID:15893423 PMID:16426572 PMID:16906435 PMID:17069994 PMID:17275222 PMID:17872374 PMID:18308446 PMID:18493746 PMID:18755850 PMID:19244278 PMID:19553035 PMID:19828881 PMID:19901195 PMID:20187624 PMID:20801209 PMID:20816883 PMID:20823264 PMID:21053930 PMID:21127131 PMID:21162728 PMID:21621526 PMID:21652769 PMID:21732638 PMID:21932800 PMID:22837390 PMID:22975028 PMID:23099484 PMID:24161567 PMID:24361490 PMID:26221077 PMID:27163632 PMID:27393915 PMID:27966929 PMID:29094188 PMID:29274324 PMID:30508555 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
affects binding
increases expression
increases metabolic processing
affects metabolic processing
decreases activity
ISO
EXP
[alpha-naphthoflavone results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin; alpha-naphthoflavone binds to and results in decreased activity of CYP1A2 protein; alpha-naphthoflavone inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA]; alpha-naphthoflavone inhibits the reaction [2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of CYP1A2 mRNA]; alpha-naphthoflavone inhibits the reaction [CYP1A2 protein results in increased metabolism of Triazines]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
CYP1A2 protein binds to alpha-naphthoflavone
alpha-naphthoflavone results in increased expression of CYP1A2 protein
[2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline co-treated with alpha-naphthoflavone] results in increased expression of CYP1A2 protein; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
[[alpha-naphthoflavone results in decreased activity of CYP1A2 protein] co-treated with [alpha-naphthoflavone results in decreased activity of CYP1A1 protein]] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]; [alpha-naphthoflavone results in decreased activity of CYP1A2 protein] which results in decreased reduction of and results in decreased oxidation of 9-anthraldehyde
CYP1A2 protein results in increased metabolism of alpha-naphthoflavone
alpha-naphthoflavone results in increased expression of CYP1A2 mRNA; alpha-naphthoflavone results in increased expression of CYP1A2 protein
CYP1A2 protein affects the metabolism of alpha-naphthoflavone
CTD PMID:2180560 PMID:9305587 PMID:15306208 PMID:15766918 PMID:15860655 PMID:17702393 PMID:18493746 PMID:19828881 PMID:20448087 PMID:20816883 PMID:21053930 PMID:21766881 PMID:21932800 PMID:26599973 PMID:27966929 PMID:28887089 PMID:29074051 PMID:33253783 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
affects binding
increases metabolic processing
increases expression
decreases expression
decreases activity
ISO
EXP
alpha-naphthoflavone binds to and results in decreased activity of CYP1B1 protein; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]; alpha-naphthoflavone inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1B1 mRNA]; alpha-naphthoflavone inhibits the reaction [[CYP1B1 protein co-treated with NADP] results in increased metabolism of 2,4,3',5'-tetramethoxystilbene]; alpha-naphthoflavone inhibits the reaction [[CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene] which results in increased expression of TP53 protein modified form]; alpha-naphthoflavone inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
CYP1B1 protein binds to alpha-naphthoflavone
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1B1 mRNA]
CYP1B1 protein results in increased metabolism of alpha-naphthoflavone
alpha-naphthoflavone inhibits the reaction [AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]]
alpha-naphthoflavone results in increased expression of CYP1B1 mRNA
alpha-naphthoflavone results in decreased expression of CYP1B1 mRNA
alpha-naphthoflavone results in decreased activity of CYP1B1 protein
CTD PMID:11577022 PMID:15075337 PMID:15280921 PMID:16120791 PMID:19182260 PMID:19563207 PMID:20823264 PMID:21053930 PMID:22262711 PMID:27163632 PMID:27966929 PMID:29146461 PMID:32553695 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP24A1 promoter]]]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]]; alpha-naphthoflavone inhibits the reaction [Cycloheximide promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]] CTD PMID:19244278 NCBI chr 3:168,097,484...168,111,920
Ensembl chr 3:168,097,485...168,111,920
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP2C11 mRNA] CTD PMID:18467041 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 multiple interactions ISO [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Skatole results in increased expression of CYP2F1 mRNA] CTD PMID:20187624 NCBI chr 1:83,933,974...83,947,804
Ensembl chr 1:83,933,942...83,947,821
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 decreases activity ISO alpha-naphthoflavone results in decreased activity of CYP2J2 protein CTD PMID:12851038 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
JBrowse link
G Dazl deleted in azoospermia-like multiple interactions ISO alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of DAZL mRNA] CTD PMID:20562217 NCBI chr 9:12,633,983...12,651,017
Ensembl chr 9:12,633,990...12,650,938
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO alpha-naphthoflavone results in increased expression of DDIT3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; ARNT protein affects the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; pyrazolanthrone inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; salubrinal inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; SB 203580 inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; SRC protein affects the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; SU 6656 inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]
CTD PMID:30508555 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DDR2 mRNA] CTD PMID:29094188 NCBI chr13:88,311,639...88,436,561
Ensembl chr13:88,317,145...88,436,789
JBrowse link
G Ddx4 DEAD-box helicase 4 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of DDX4 mRNA] CTD PMID:20562217 NCBI chr 2:44,447,610...44,504,263
Ensembl chr 2:44,447,573...44,504,354
JBrowse link
G Ddx5 DEAD-box helicase 5 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DDX5 mRNA] CTD PMID:29094188 NCBI chr10:94,979,759...94,988,461
Ensembl chr10:94,980,928...94,988,461
JBrowse link
G Dll1 delta like canonical Notch ligand 1 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DLL1 mRNA] CTD PMID:29094188 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 decreases methylation
multiple interactions
EXP alpha-naphthoflavone results in decreased methylation of DNAJB6 promoter
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to DNAJB6 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of DNAJB6 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DNAJB6 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of DNAJB6 promoter]
CTD PMID:29094188 NCBI chr 4:2,711,329...2,774,969
Ensembl chr 4:2,711,385...2,774,890
JBrowse link
G Dusp5 dual specificity phosphatase 5 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 mRNA]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 protein] CTD PMID:19578757 NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:17934341 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of EGLN1 mRNA]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of EGLN1 protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of EGLN1 mRNA] CTD PMID:18072750 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation ISO alpha-naphthoflavone results in increased phosphorylation of EIF2S1 protein CTD PMID:30508555 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Eno1 enolase 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ENO1 mRNA] CTD PMID:23152189 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Oxygen deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of ENPP2 mRNA]]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of ENPP2 mRNA] CTD PMID:19028555 NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
JBrowse link
G Ervfrd-1 endogenous retrovirus group FRD member 1, envelope multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of ERVFRD-1 mRNA] CTD PMID:24361490 NCBI chr12:25,161,130...25,168,182
Ensembl chr12:25,161,130...25,168,182
JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions
ISO
EXP
[alpha-naphthoflavone binds to AHR protein] which binds to ESR1 protein
alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [Estradiol binds to ESR1 protein]]; alpha-naphthoflavone inhibits the reaction [Particulate Matter analog inhibits the reaction [Estradiol binds to ESR1 protein]]; alpha-naphthoflavone inhibits the reaction [Vehicle Emissions analog inhibits the reaction [Estradiol binds to ESR1 protein]]
[alpha-naphthoflavone co-treated with beta-Naphthoflavone] results in decreased expression of ESR1 mRNA; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of ESR1 mRNA]
CTD PMID:10620335 PMID:15253042 PMID:22975028 PMID:29094188 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions EXP [alpha-naphthoflavone co-treated with beta-Naphthoflavone] results in decreased expression of ESR2 mRNA CTD PMID:22975028 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Esrra estrogen related receptor, alpha affects binding ISO [alpha-naphthoflavone binds to AHR protein] which binds to ESRRA protein CTD PMID:10620335 NCBI chr 1:222,168,729...222,178,842
Ensembl chr 1:222,168,730...222,178,725
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of FAS mRNA] CTD PMID:16940415 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of FASL mRNA] CTD PMID:16940415 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein]] CTD PMID:20876236 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Flg filaggrin multiple interactions ISO [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of FLG mRNA] CTD PMID:21835898 NCBI chr 2:193,565,401...193,574,297 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of FOS mRNA]] CTD PMID:10478842 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxn3 forkhead box N3 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of FOXN3 mRNA] CTD PMID:29094188 NCBI chr 6:123,183,720...123,577,719
Ensembl chr 6:123,187,726...123,577,695
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO
EXP
alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased phosphorylation of FOXO3 protein]
[Methylcholanthrene co-treated with alpha-naphthoflavone] results in increased expression of FOXO3 mRNA
CTD PMID:22266097 PMID:29094188 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Foxp3 forkhead box P3 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [tetrandrine results in increased expression of FOXP3 mRNA] CTD PMID:26640276 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Fshr follicle stimulating hormone receptor multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FSHR protein] CTD PMID:20823264 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
G Gdf9 growth differentiation factor 9 increases expression
multiple interactions
EXP alpha-naphthoflavone results in increased expression of GDF9 mRNA
[Methylcholanthrene co-treated with alpha-naphthoflavone] results in increased expression of GDF9 mRNA
CTD PMID:29094188 NCBI chr10:38,782,519...38,793,238
Ensembl chr10:38,788,992...38,792,940
JBrowse link
G Gpi glucose-6-phosphate isomerase multiple interactions
increases expression
ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of GPI mRNA]
alpha-naphthoflavone results in increased expression of GPI mRNA
CTD PMID:23152189 NCBI chr 1:90,063,411...90,091,287
Ensembl chr 1:90,063,411...90,091,287
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of GSR mRNA] CTD PMID:23152189 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression ISO alpha-naphthoflavone results in decreased expression of GSTP1 mRNA CTD PMID:18762178 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to HES1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of HES1 mRNA] CTD PMID:29094188 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hk1 hexokinase 1 multiple interactions
increases expression
ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of HK1 mRNA]
alpha-naphthoflavone results in increased expression of HK1 mRNA
CTD PMID:23152189 NCBI chr20:31,911,460...31,979,780
Ensembl chr20:31,912,262...31,956,649
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased expression of HMGCR mRNA]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased expression of HMGCR protein] CTD PMID:19931295 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of HSPA8 mRNA] CTD PMID:29094188 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of ICAM1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to ICAM1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of ICAM1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of ICAM1 mRNA] CTD PMID:26519956 PMID:29094188 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Igf2 insulin-like growth factor 2 decreases acetylation
multiple interactions
EXP alpha-naphthoflavone results in decreased acetylation of IGF2 promoter
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to IGF2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of IGF2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of IGF2 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of IGF2 promoter]
CTD PMID:29094188 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 multiple interactions
increases expression
EXP AHR gene mutant form inhibits the reaction [alpha-naphthoflavone results in increased expression of IGFBP4 protein] CTD PMID:23639626 NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578
JBrowse link
G Il10 interleukin 10 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [[Benzo(a)pyrene co-treated with Lipopolysaccharides] affects the expression of IL10 mRNA]; alpha-naphthoflavone inhibits the reaction [[Benzo(a)pyrene co-treated with Lipopolysaccharides] affects the expression of IL10 protein]
[alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of IL10 protein]; alpha-naphthoflavone inhibits the reaction [tetrandrine results in increased expression of IL10 mRNA]
CTD PMID:11737050 PMID:17681673 PMID:26640276 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
decreases expression
ISO alpha-naphthoflavone analog inhibits the reaction [IL1B protein results in increased expression of SAA1 mRNA]; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B mRNA]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of IL1B mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of IL1B mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IL1B mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IL1B protein]
alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of IL1B mRNA]
alpha-naphthoflavone results in increased expression of IL1B mRNA
alpha-naphthoflavone results in decreased expression of IL1B mRNA
CTD PMID:14993811 PMID:15019843 PMID:18617548 PMID:21127131 PMID:22262711 PMID:27393915 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions
increases expression
ISO alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1RN mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IL1RN mRNA]
alpha-naphthoflavone results in increased expression of IL1RN mRNA
CTD PMID:22262711 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO
EXP
alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of IL6 mRNA]; alpha-naphthoflavone inhibits the reaction [Vehicle Emissions results in increased expression of IL6 mRNA]
alpha-naphthoflavone inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of IL6 mRNA]
alpha-naphthoflavone results in increased expression of IL6 mRNA
CTD PMID:21162728 PMID:26519956 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Itgb8 integrin subunit beta 8 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of ITGB8 mRNA] CTD PMID:29094188 NCBI chr 6:147,089,280...147,172,846
Ensembl chr 6:147,094,097...147,172,813
JBrowse link
G Jag1 jagged canonical Notch ligand 1 decreases methylation
multiple interactions
EXP alpha-naphthoflavone results in decreased methylation of JAG1 promoter
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to JAG1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of JAG1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of JAG1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of JAG1 promoter]
CTD PMID:29094188 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO
EXP
alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of JUN protein]
alpha-naphthoflavone results in increased expression of JUN mRNA
CTD PMID:15019843 PMID:15897893 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Krt14 keratin 14 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Plant Extracts results in decreased expression of KRT14 mRNA] CTD PMID:25051199 NCBI chr10:88,118,029...88,122,233
Ensembl chr10:88,055,823...88,122,233
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions
increases expression
ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of LDHA mRNA]
alpha-naphthoflavone results in increased expression of LDHA mRNA
CTD PMID:23152189 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of LHCGR protein] CTD PMID:20823264 NCBI chr 6:12,493,182...12,554,482
Ensembl chr 6:12,493,943...12,554,439
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of and results in increased activity of MAPK1 protein]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in increased phosphorylation of MAPK1 protein]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]]; alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of MAPK1 protein]
alpha-naphthoflavone results in increased phosphorylation of MAPK1 protein
SU 6656 inhibits the reaction [alpha-naphthoflavone results in increased phosphorylation of MAPK1 protein]
CTD PMID:19578757 PMID:20876236 PMID:21205633 PMID:26358519 PMID:30508555 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of and results in increased activity of MAPK3 protein]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in increased phosphorylation of MAPK3 protein]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein]]; alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of MAPK3 protein]
SU 6656 inhibits the reaction [alpha-naphthoflavone results in increased phosphorylation of MAPK3 protein]
CTD PMID:19578757 PMID:20876236 PMID:21205633 PMID:26358519 PMID:30508555 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [Oxygen deficiency results in increased expression of MDM2 mRNA]]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MDM2 mRNA] CTD PMID:19578757 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions EXP
ISO
alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of MMP1 mRNA]
alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]; alpha-naphthoflavone inhibits the reaction [Tretinoin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA]]
CTD PMID:15075337 PMID:19022365 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of MMP2 mRNA] CTD PMID:19022365 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of MMP3 mRNA] CTD PMID:19022365 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP
ISO
alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of MMP9 mRNA]
alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased secretion of and results in increased activity of MMP9 protein]
CTD PMID:19022365 PMID:23462309 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mt1 metallothionein 1 increases expression ISO alpha-naphthoflavone results in increased expression of MT1 mRNA CTD PMID:14998373 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased phosphorylation of MTOR protein] CTD PMID:22266097 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased expression of MYC protein] CTD PMID:22100782 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myog myogenin multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in decreased expression of MYOG protein] CTD PMID:24431215 NCBI chr13:51,126,459...51,129,048
Ensembl chr13:51,126,459...51,129,048
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of NCF1 mRNA] CTD PMID:19559082 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of NDUFS1 mRNA] CTD PMID:23152189 NCBI chr 9:69,919,863...69,953,182
Ensembl chr 9:69,919,867...69,953,182
JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of NDUFS3 mRNA] CTD PMID:23152189 NCBI chr 3:79,721,686...79,728,863
Ensembl chr 3:79,721,694...79,728,879
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of NFATC1 protein] CTD PMID:19028555 NCBI chr18:77,203,517...77,322,690
Ensembl chr18:77,203,525...77,322,690
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
EXP
ISO
alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of NOS2 protein]
alpha-naphthoflavone results in increased expression of NOS2 protein
CTD PMID:26086121 PMID:33722737 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Notch2 notch receptor 2 decreases acetylation
increases methylation
multiple interactions
EXP alpha-naphthoflavone results in decreased acetylation of NOTCH2 promoter
alpha-naphthoflavone results in increased methylation of NOTCH2 promoter
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of NOTCH2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of NOTCH2 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of NOTCH2 promoter]
CTD PMID:29094188 NCBI chr 2:200,187,184...200,320,403
Ensembl chr 2:200,187,179...200,320,215
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases activity
increases expression
EXP alpha-naphthoflavone results in increased activity of NQO1 protein
alpha-naphthoflavone results in increased expression of NQO1 mRNA
CTD PMID:16906435 PMID:17069994 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity EXP alpha-naphthoflavone results in increased activity of NR1I3 protein CTD PMID:27732639 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 affects binding ISO [alpha-naphthoflavone binds to AHR protein] which binds to NR2F1 protein CTD PMID:10620335 NCBI chr 2:5,569,954...5,579,894
Ensembl chr 2:5,569,935...5,579,894
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO alpha-naphthoflavone results in increased cleavage of PARP1 protein CTD PMID:30508555 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pfkm phosphofructokinase, muscle multiple interactions
increases expression
ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PFKM mRNA]
alpha-naphthoflavone results in increased expression of PFKM mRNA
CTD PMID:23152189 NCBI chr 7:139,702,066...139,722,132
Ensembl chr 7:139,685,573...139,722,132
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions
increases expression
ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PGK1 mRNA]
alpha-naphthoflavone results in increased expression of PGK1 mRNA
CTD PMID:23152189 NCBI chr  X:77,263,399...77,279,373
Ensembl chr  X:77,263,359...77,279,367
JBrowse link
G Pgm1 phosphoglucomutase 1 increases expression
multiple interactions
ISO alpha-naphthoflavone results in increased expression of PGM1 mRNA
alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PGM1 mRNA]
CTD PMID:23152189 NCBI chr 5:118,743,632...118,803,055
Ensembl chr 5:118,743,632...118,803,055
JBrowse link
G Pgr progesterone receptor increases expression ISO alpha-naphthoflavone results in increased expression of PGR protein CTD PMID:22266097 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Pkm pyruvate kinase M1/2 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PKM mRNA] CTD PMID:23152189 NCBI chr 8:64,480,963...64,502,957
Ensembl chr 8:64,481,172...64,502,722
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO alpha-naphthoflavone inhibits the reaction [beta-Naphthoflavone results in increased expression of PPARA protein] CTD PMID:21849270 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Prdm1 PR/SET domain 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of PRDM1 mRNA] CTD PMID:20562217 NCBI chr20:49,464,921...49,556,623
Ensembl chr20:49,464,919...49,556,518
JBrowse link
G Prkcb protein kinase C, beta multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of PRKCB protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased localization of PRKCB protein] CTD PMID:16797713 PMID:17222441 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prl prolactin multiple interactions EXP alpha-naphthoflavone promotes the reaction [beta-Naphthoflavone results in decreased expression of PRL mRNA] CTD PMID:22975028 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions
increases expression
ISO alpha-naphthoflavone results in decreased expression of PTGS2 mRNA
alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]
alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTGS2 mRNA]; alpha-naphthoflavone inhibits the reaction [Chlorpyrifos results in increased expression of PTGS2 protein]; alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased expression of PTGS2 protein]; alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; alpha-naphthoflavone inhibits the reaction [Vehicle Emissions results in increased expression of PTGS2 mRNA]; alpha-naphthoflavone promotes the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]
alpha-naphthoflavone results in increased expression of PTGS2 mRNA
CTD PMID:21162728 PMID:21652769 PMID:22262711 PMID:26358519 PMID:27393915 PMID:32526215 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased phosphorylation of PTK2 protein] CTD PMID:16359657 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119
JBrowse link
G Rack1 receptor for activated C kinase 1 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of RACK1 protein] CTD PMID:16797713 PMID:17222441 NCBI chr10:34,149,717...34,155,198
Ensembl chr10:34,149,717...34,155,198
Ensembl chr12:34,149,717...34,155,198
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased phosphorylation of RB1 protein] CTD PMID:15157999 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases expression
ISO alpha-naphthoflavone inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of RELA protein]; alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of RELA protein]
alpha-naphthoflavone results in decreased expression of RELA protein
CTD PMID:24431215 PMID:33722737 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Serpinb2 serpin family B member 2 multiple interactions
decreases expression
increases expression
ISO alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SERPINB2 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINB2 mRNA]; alpha-naphthoflavone inhibits the reaction [Tretinoin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINB2 mRNA]]
alpha-naphthoflavone results in decreased expression of SERPINB2 mRNA
alpha-naphthoflavone results in increased expression of SERPINB2 mRNA
CTD PMID:15075337 PMID:22262711 NCBI chr13:27,449,907...27,463,015
Ensembl chr13:27,449,934...27,463,010
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions
increases expression
ISO alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SLC2A1 mRNA]
alpha-naphthoflavone results in increased expression of SLC2A1 mRNA
CTD PMID:23152189 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions EXP alpha-naphthoflavone inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in decreased expression of SLC5A5 protein] CTD PMID:26519956 NCBI chr16:20,297,414...20,307,401
Ensembl chr16:20,297,414...20,307,400
JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of SMAD3 protein] CTD PMID:27519288 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to SP1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of SP1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of SP1 mRNA] CTD PMID:29094188 NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions
increases phosphorylation
ISO SRC protein affects the reaction [alpha-naphthoflavone results in increased expression of CYP1A1 mRNA]; SRC protein affects the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]
alpha-naphthoflavone results in increased phosphorylation of SRC protein
CTD PMID:30508555 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Stat5b signal transducer and activator of transcription 5B multiple interactions ISO [alpha-naphthoflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of and results in increased activity of STAT5B protein] CTD PMID:21205633 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829
JBrowse link
G Tcf7 transcription factor 7 increases expression ISO alpha-naphthoflavone results in increased expression of TCF7 mRNA CTD PMID:18762178 NCBI chr10:37,616,033...37,646,027
Ensembl chr10:37,617,279...37,645,802
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP
ISO
alpha-naphthoflavone promotes the reaction [beta-Naphthoflavone results in decreased expression of TGFB1 mRNA]
alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased expression of TGFB1 mRNA]
CTD PMID:22975028 PMID:27519288 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase decreases expression
multiple interactions
ISO alpha-naphthoflavone results in decreased expression of TIPARP mRNA
alpha-naphthoflavone promotes the reaction [Particulate Matter results in increased expression of TIPARP mRNA]
CTD PMID:18762178 PMID:21652769 NCBI chr 2:157,316,293...157,342,979
Ensembl chr 2:157,316,266...157,341,469
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of TNF mRNA]
alpha-naphthoflavone inhibits the reaction [Particulate Matter results in increased expression of TNF mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased secretion of TNF protein]
CTD PMID:17934341 PMID:20801209 PMID:23099484 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [norisoboldine inhibits the reaction [TNFSF11 protein results in increased expression of VEGFA mRNA]] CTD PMID:26221077 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
EXP
ISO
alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [leptomycin B results in increased expression of TP53 protein]]
alpha-naphthoflavone inhibits the reaction [[CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene] which results in increased expression of TP53 protein modified form]
alpha-naphthoflavone results in increased expression of TP53 protein
alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene affects the localization of TRP53 protein]
CTD PMID:9006915 PMID:15459018 PMID:29274324 PMID:32553695 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression
multiple interactions
ISO alpha-naphthoflavone results in increased expression of TPI1 mRNA
alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TPI1 mRNA]
CTD PMID:23152189 NCBI chr 4:157,328,375...157,331,905
Ensembl chr 4:157,328,379...157,331,905
Ensembl chr 9:157,328,379...157,331,905
JBrowse link
G Vdr vitamin D receptor multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP24A1 promoter]]] CTD PMID:19244278 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO
EXP
alpha-naphthoflavone affects the reaction [Hexachlorobenzene results in increased expression of VEGFA protein]; alpha-naphthoflavone inhibits the reaction [Hexachlorobenzene results in increased secretion of VEGFA protein]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA protein]; alpha-naphthoflavone promotes the reaction [Chlorpyrifos results in increased expression of VEGFA protein]
alpha-naphthoflavone inhibits the reaction [norisoboldine results in decreased expression of VEGFA mRNA]
alpha-naphthoflavone inhibits the reaction [norisoboldine inhibits the reaction [TNFSF11 protein results in increased expression of VEGFA mRNA]]
CTD PMID:19182260 PMID:26221077 PMID:26358519 PMID:32526215 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Wapl WAPL cohesin release factor multiple interactions ISO alpha-naphthoflavone promotes the reaction [3-methylcholanthrylene results in increased expression of WAPL mRNA] CTD PMID:15797623 NCBI chr16:11,029,325...11,108,867
Ensembl chr16:11,032,531...11,106,589
JBrowse link
amentoflavone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aif1 allograft inflammatory factor 1 multiple interactions ISO amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of AIF1 protein] CTD PMID:28185818 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of BAX protein] CTD PMID:28185818 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BCL2 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]]; amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]
CTD PMID:28185818 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CASP3 protein modified form]]; amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CASP3 protein modified form] CTD PMID:28185818 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CDKN1A protein] CTD PMID:28185818 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO amentoflavone results in decreased activity of CYP1B1 protein CTD PMID:16271822 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Dct dopachrome tautomerase decreases expression ISO amentoflavone analog results in decreased expression of DCT mRNA; amentoflavone analog results in decreased expression of DCT protein CTD PMID:17473463 NCBI chr15:103,208,174...103,245,033
Ensembl chr15:103,208,258...103,244,494
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein] CTD PMID:28185818 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B protein] CTD PMID:28185818 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]]; amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein] CTD PMID:28185818 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]]; amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein] CTD PMID:28185818 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression
multiple interactions
ISO amentoflavone results in decreased expression of NOS2 protein
amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of NOS2 protein]
CTD PMID:12144868 PMID:28185818 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Ptgds prostaglandin D2 synthase affects binding ISO amentoflavone binds to PTGDS protein CTD PMID:26456343 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions
ISO amentoflavone results in decreased expression of PTGS2 mRNA; amentoflavone results in decreased expression of PTGS2 protein
[amentoflavone results in decreased expression of PTGS2 protein] which results in decreased chemical synthesis of Dinoprostone
CTD PMID:12144868 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH mRNA]; amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein] CTD PMID:28185818 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Tyr tyrosinase decreases activity ISO amentoflavone analog results in decreased activity of TYR protein CTD PMID:17473463 NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 decreases activity ISO amentoflavone results in decreased activity of UGT1A1 protein CTD PMID:29470958 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 decreases activity ISO amentoflavone results in decreased activity of UGT1A3 protein CTD PMID:29470958 NCBI chr 9:95,285,592...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 decreases activity ISO amentoflavone results in decreased activity of UGT1A4 protein CTD PMID:29470958 NCBI chr 9:95,256,628...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 decreases activity
multiple interactions
ISO amentoflavone results in decreased activity of UGT1A6 protein
amentoflavone inhibits the reaction [UGT1A6 protein results in increased glucuronidation of 4-cresol]
CTD PMID:29470958 PMID:32421801 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 decreases activity ISO amentoflavone results in decreased activity of UGT1A8 protein CTD PMID:29470958 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 decreases activity ISO amentoflavone results in decreased activity of UGT1A9 protein CTD PMID:29470958 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 decreases activity ISO amentoflavone results in decreased activity of UGT2B17 protein CTD PMID:29470958 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
aminoglutethimide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp1 acid phosphatase 1 decreases expression ISO Aminoglutethimide results in decreased expression of ACP1 protein CTD PMID:26102013 NCBI chr 6:49,836,064...49,851,714
Ensembl chr 6:49,836,075...49,851,714
JBrowse link
G Anp32b acidic nuclear phosphoprotein 32 family member B decreases expression ISO Aminoglutethimide results in decreased expression of ANP32B protein CTD PMID:26102013 NCBI chr 5:62,070,709...62,094,633
Ensembl chr 5:62,071,346...62,094,633
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 decreases expression ISO Aminoglutethimide results in decreased expression of BASP1 protein CTD PMID:26102013 NCBI chr 2:77,586,424...77,632,626
Ensembl chr 2:77,586,424...77,632,628
JBrowse link
G Bcap31 B-cell receptor-associated protein 31 decreases expression ISO Aminoglutethimide results in decreased expression of BCAP31 protein CTD PMID:26102013 NCBI chr  X:157,094,365...157,126,397
Ensembl chr  X:157,095,937...157,126,393
JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 increases expression ISO Aminoglutethimide results in increased expression of CCT4 protein CTD PMID:26102013 NCBI chr14:107,767,392...107,780,270
Ensembl chr14:107,767,392...107,780,270
JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A decreases expression ISO Aminoglutethimide results in decreased expression of CCT6A protein CTD PMID:26102013 NCBI chr12:30,491,584...30,501,813
Ensembl chr12:30,491,416...30,501,860
JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 decreases expression ISO Aminoglutethimide results in decreased expression of CCT7 protein CTD PMID:26102013 NCBI chr 4:117,235,023...117,252,265
Ensembl chr 4:117,235,023...117,252,265
JBrowse link
G Comt catechol-O-methyltransferase increases expression ISO Aminoglutethimide results in increased expression of COMT protein CTD PMID:26102013 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Cuta cutA divalent cation tolerance homolog decreases expression ISO Aminoglutethimide results in decreased expression of CUTA protein CTD PMID:26102013 NCBI chr20:5,532,024...5,533,640
Ensembl chr20:5,532,024...5,533,620
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO Aminoglutethimide inhibits the reaction [Colforsin results in increased expression of CYP11A1 mRNA] CTD PMID:16935330 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO Aminoglutethimide results in decreased expression of CYP17A1 mRNA CTD PMID:16935330 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
increases activity
decreases activity
ISO Aminoglutethimide inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]; Aminoglutethimide inhibits the reaction [CYP19A1 protein affects the chemical synthesis of 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine]; Aminoglutethimide inhibits the reaction [CYP19A1 protein affects the metabolism of Methadone]
Aminoglutethimide results in increased activity of CYP19A1 protein
Aminoglutethimide results in decreased activity of CYP19A1 protein
CTD PMID:15242824 PMID:15968818 PMID:16935330 PMID:17910019 PMID:20087668 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Fshb follicle stimulating hormone subunit beta decreases expression
multiple interactions
ISO Aminoglutethimide results in decreased expression of FSHB protein
Aminoglutethimide inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased abundance of Acetaldehyde]
CTD PMID:9208491 PMID:22285649 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Gatd3a glutamine amidotransferase class 1 domain containing 3A increases expression ISO Aminoglutethimide results in increased expression of GATD3 protein CTD PMID:26102013 NCBI chr20:11,244,353...11,252,450
Ensembl chr20:11,244,353...11,252,449
JBrowse link
G Gns glucosamine (N-acetyl)-6-sulfatase decreases expression ISO Aminoglutethimide results in decreased expression of GNS protein CTD PMID:26102013 NCBI chr 7:63,467,027...63,501,054
Ensembl chr 7:63,467,216...63,499,353
Ensembl chr 7:63,467,216...63,499,353
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO Aminoglutethimide results in increased expression of GPX1 protein CTD PMID:26102013 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsn gelsolin decreases expression ISO Aminoglutethimide results in decreased expression of GSN protein CTD PMID:26102013 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO Aminoglutethimide results in increased expression of H1-2 protein CTD PMID:26102013 NCBI chr17:43,638,938...43,640,445
Ensembl chr17:43,639,749...43,640,387
JBrowse link
G H2ac12 H2A clustered histone 12 increases expression ISO Aminoglutethimide results in increased expression of H2AC12 protein CTD PMID:26102013 NCBI chr17:44,527,990...44,528,557
Ensembl chr17:44,528,125...44,528,511
JBrowse link
G H2az1 H2A.Z variant histone 1 increases expression ISO Aminoglutethimide results in increased expression of H2AZ1 protein CTD PMID:26102013 NCBI chr 2:243,105,224...243,107,333
Ensembl chr 2:243,105,674...243,106,956
JBrowse link
G H2bc12 H2B clustered histone 12 increases expression ISO Aminoglutethimide results in increased expression of H2BC12 protein CTD PMID:26102013 NCBI chr17:44,527,421...44,527,801
Ensembl chr17:44,527,421...44,527,801
JBrowse link
G H3c13 H3 clustered histone 13 increases expression ISO Aminoglutethimide results in increased expression of H3C13 protein CTD PMID:26102013 NCBI chr17:43,776,018...43,776,779
Ensembl chr17:43,791,657...43,792,067
Ensembl chr17:43,791,657...43,792,067
Ensembl chr17:43,791,657...43,792,067
Ensembl chr 2:43,791,657...43,792,067
Ensembl chr17:43,791,657...43,792,067
Ensembl chr17:43,791,657...43,792,067
Ensembl chr 2:43,791,657...43,792,067
Ensembl chr 2:43,791,657...43,792,067
JBrowse link
G Hmgb2 high mobility group box 2 decreases expression ISO Aminoglutethimide results in decreased expression of HMGB2 protein CTD PMID:26102013 NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191
Ensembl chr11:36,077,617...36,080,191
JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 decreases expression ISO Aminoglutethimide results in decreased expression of HNRNPH1 protein CTD PMID:26102013 NCBI chr10:35,872,619...35,879,911
Ensembl chr10:35,870,232...35,879,910
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 multiple interactions ISO [Colforsin co-treated with Aminoglutethimide] results in decreased expression of HSD17B1 mRNA CTD PMID:16935330 NCBI chr10:88,987,558...88,989,758
Ensembl chr10:88,987,558...88,989,757
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 decreases expression ISO Aminoglutethimide results in decreased expression of HSD17B10 protein CTD PMID:26102013 NCBI chr  X:21,696,796...21,699,241
Ensembl chr  X:21,696,772...21,699,241
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 multiple interactions
decreases expression
ISO Aminoglutethimide inhibits the reaction [Colforsin results in increased expression of HSD17B4 mRNA]
Aminoglutethimide results in decreased expression of HSD17B4 mRNA
CTD PMID:16935330 NCBI chr18:44,810,462...44,897,677
Ensembl chr18:44,810,388...44,897,640
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 decreases expression EXP Aminoglutethimide results in decreased expression of HSD17B7 mRNA CTD PMID:9231770 NCBI chr13:88,288,116...88,308,019
Ensembl chr13:88,288,046...88,307,988
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO Aminoglutethimide results in increased expression of HSPA1A protein CTD PMID:26102013 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hyou1 hypoxia up-regulated 1 increases expression ISO Aminoglutethimide results in increased expression of HYOU1 protein CTD PMID:26102013 NCBI chr 8:48,699,796...48,711,912
Ensembl chr 8:48,699,769...48,711,910
JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 decreases expression ISO Aminoglutethimide results in decreased expression of IMPDH2 protein CTD PMID:26102013 NCBI chr 8:117,346,983...117,351,619
Ensembl chr 8:117,347,029...117,351,610
JBrowse link
G Lhb luteinizing hormone subunit beta decreases expression
multiple interactions
ISO Aminoglutethimide results in decreased expression of LHB protein
Aminoglutethimide inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased abundance of Acetaldehyde]
CTD PMID:9208491 PMID:22285649 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Lmna lamin A/C decreases expression ISO Aminoglutethimide results in decreased expression of LMNA protein CTD PMID:26102013 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G Lmnb2 lamin B2 decreases expression ISO Aminoglutethimide results in decreased expression of LMNB2 protein CTD PMID:26102013 NCBI chr 7:11,657,870...11,676,936
Ensembl chr 7:11,660,934...11,675,472
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 decreases expression ISO Aminoglutethimide results in decreased expression of MCM3 protein CTD PMID:26102013 NCBI chr 9:26,914,057...26,932,201
Ensembl chr 9:26,914,057...26,932,201
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO [[MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of Aminoglutethimide] which results in increased expression of MPO protein modified form; [Aminoglutethimide co-treated with Hydrogen Peroxide] results in increased oxidation of MPO protein; [MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of Aminoglutethimide CTD PMID:20199096 PMID:26102013 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Myo18a myosin XVIIIa decreases expression ISO Aminoglutethimide results in decreased expression of MYO18A protein CTD PMID:26102013 NCBI chr10:64,979,770...65,080,535
Ensembl chr10:64,979,770...65,080,535
JBrowse link
G Npm3 nucleophosmin/nucleoplasmin, 3 decreases expression ISO Aminoglutethimide results in decreased expression of NPM3 protein CTD PMID:26102013 NCBI chr 1:265,504,105...265,506,080
Ensembl chr 1:265,504,575...265,506,046
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Aminoglutethimide results in increased activity of NR1I2 protein CTD PMID:21068194 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nup210 nucleoporin 210 decreases expression ISO Aminoglutethimide results in decreased expression of NUP210 protein CTD PMID:26102013 NCBI chr 4:122,643,952...122,741,322
Ensembl chr 4:122,644,135...122,741,110
JBrowse link
G Pgr progesterone receptor multiple interactions
decreases expression
ISO [Aminoglutethimide co-treated with 17 alpha-Hydroxyprogesterone Caproate] results in decreased expression of PGR protein
Aminoglutethimide results in decreased expression of PGR protein
CTD PMID:8565696 PMID:9208491 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Pitpnb phosphatidylinositol transfer protein, beta increases expression ISO Aminoglutethimide results in increased expression of PITPNB protein CTD PMID:26102013 NCBI chr12:51,279,194...51,341,752
Ensembl chr12:51,280,150...51,341,716
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha decreases expression ISO Aminoglutethimide results in decreased expression of PPP1CA protein CTD PMID:26102013 NCBI chr 1:219,439,953...219,443,570
Ensembl chr 1:219,439,953...219,443,570
JBrowse link
G Prdx3 peroxiredoxin 3 increases expression ISO Aminoglutethimide results in increased expression of PRDX3 protein CTD PMID:26102013 NCBI chr 1:282,238,774...282,251,193
Ensembl chr 1:282,238,773...282,251,257
JBrowse link
G Psmb4 proteasome 20S subunit beta 4 decreases expression ISO Aminoglutethimide results in decreased expression of PSMB4 protein CTD PMID:26102013 NCBI chr 2:196,043,546...196,046,320
Ensembl chr 2:196,043,618...196,046,311
JBrowse link
G Rtraf RNA transcription, translation and transport factor decreases expression ISO Aminoglutethimide results in decreased expression of RTRAF protein CTD PMID:26102013 NCBI chr15:4,882,925...4,893,890
Ensembl chr15:4,882,947...4,893,919
JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression EXP Aminoglutethimide results in decreased expression of SPP1 mRNA CTD PMID:23558518 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Ssb small RNA binding exonuclease protection factor La decreases expression ISO Aminoglutethimide results in decreased expression of SSB protein CTD PMID:26102013 NCBI chr 3:56,092,425...56,102,008
Ensembl chr 3:56,092,501...56,102,001
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression
increases expression
ISO Aminoglutethimide results in decreased expression of STAR mRNA
Aminoglutethimide results in increased expression of STAR mRNA
CTD PMID:10960482 PMID:16935330 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 decreases expression ISO Aminoglutethimide results in decreased expression of TPT1 protein CTD PMID:26102013 NCBI chr15:57,891,680...57,894,504
Ensembl chr15:57,891,680...57,894,504
JBrowse link
G Ubc ubiquitin C increases expression ISO Aminoglutethimide results in increased expression of UBC protein CTD PMID:26102013 NCBI chr12:36,638,457...36,642,734
Ensembl chr12:36,638,457...36,642,734
JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K decreases expression ISO Aminoglutethimide results in decreased expression of UBE2K protein CTD PMID:26102013 NCBI chr14:44,289,247...44,348,691
Ensembl chr14:44,289,247...44,348,691
JBrowse link
G Wdr1 WD repeat domain 1 increases expression ISO Aminoglutethimide results in increased expression of WDR1 protein CTD PMID:26102013 NCBI chr14:76,990,014...77,023,739
Ensembl chr14:76,989,919...77,023,726
JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta increases expression ISO Aminoglutethimide results in increased expression of YWHAQ protein CTD PMID:26102013 NCBI chr 6:43,463,294...43,493,816
Ensembl chr 6:43,463,294...43,493,816
JBrowse link
anastrozole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cycs cytochrome c, somatic multiple interactions ISO [Oleic Acid co-treated with anastrozole] affects the localization of CYCS protein; [Olive Oil co-treated with anastrozole] affects the localization of CYCS protein CTD PMID:24161488 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO Anastrozole results in decreased activity of CYP19A1 protein CTD PMID:15837728 PMID:16001952 PMID:16023338 PMID:16023854 PMID:16034487 PMID:16054421 PMID:21341743 PMID:32764486 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Fshb follicle stimulating hormone subunit beta increases expression EXP anastrozole results in increased expression of FSHB protein CTD PMID:10657858 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression ISO anastrozole results in decreased expression of GJA1 protein CTD PMID:29180066 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Lhb luteinizing hormone subunit beta increases expression EXP anastrozole results in increased expression of LHB protein CTD PMID:10657858 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions
decreases expression
ISO [Tamoxifen co-treated with anastrozole] results in decreased expression of MKI67 protein
anastrozole results in decreased expression of MKI67 protein
CTD PMID:15767642 PMID:16002280 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Pgr progesterone receptor decreases expression ISO anastrozole results in decreased expression of PGR protein CTD PMID:16002280 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO anastrozole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
beauvericin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatf apoptosis antagonizing transcription factor decreases expression ISO beauvericin results in decreased expression of AATF mRNA CTD PMID:29203277 NCBI chr10:71,744,648...71,837,851
Ensembl chr10:71,744,659...71,837,851
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ABCA1 mRNA CTD PMID:31100301 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ABCG1 mRNA CTD PMID:31100301 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ACAT2 protein CTD PMID:32407736 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
JBrowse link
G Acin1 apoptotic chromatin condensation inducer 1 decreases expression ISO beauvericin results in decreased expression of ACIN1 mRNA CTD PMID:29203277 NCBI chr15:33,288,369...33,333,256
Ensembl chr15:33,288,374...33,333,417
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ACSL4 protein CTD PMID:32407736 NCBI chr  X:113,596,247...113,660,024
Ensembl chr  X:113,596,239...113,659,944
JBrowse link
G Actb actin, beta decreases expression ISO beauvericin results in decreased expression of ACTB mRNA CTD PMID:29203277 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Aen apoptosis enhancing nuclease decreases expression ISO beauvericin results in decreased expression of AEN mRNA CTD PMID:29203277 NCBI chr 1:140,584,328...140,593,749
Ensembl chr 1:140,584,380...140,593,745
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 decreases expression ISO beauvericin results in decreased expression of AIFM1 mRNA CTD PMID:29203277 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Ak4 adenylate kinase 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of AK4 mRNA CTD PMID:31100301 NCBI chr 5:120,250,318...120,309,153
Ensembl chr 5:120,250,616...120,305,897
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ALDH5A1 protein CTD PMID:32407736 NCBI chr17:42,133,076...42,159,413
Ensembl chr17:42,133,076...42,159,413
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A decreases expression ISO beauvericin results in decreased expression of ALDOA mRNA CTD PMID:29203277 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Anapc13 anaphase promoting complex subunit 13 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ANAPC13 protein CTD PMID:32407736 NCBI chr 8:111,107,358...111,115,774
Ensembl chr 8:111,107,358...111,115,774
JBrowse link
G Aprt adenine phosphoribosyl transferase decreases expression ISO beauvericin results in decreased expression of APRT mRNA CTD PMID:29203277 NCBI chr19:55,387,288...55,389,256
Ensembl chr19:55,387,288...55,389,256
JBrowse link
G Ar androgen receptor multiple interactions ISO beauvericin inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA] CTD PMID:30716354 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO beauvericin results in decreased expression of ARHGDIA mRNA CTD PMID:29203277 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
JBrowse link
G Arpp21 cAMP regulated phosphoprotein 21 increases expression ISO beauvericin results in increased expression of ARPP21 mRNA CTD PMID:29203277 NCBI chr 8:120,323,895...120,492,790
Ensembl chr 8:120,323,897...120,446,507
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of ATP1A1 protein CTD PMID:32407736 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ATP1A3 protein CTD PMID:32407736 NCBI chr 1:81,852,423...81,881,565
Ensembl chr 1:81,852,429...81,881,549
JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ATP5PB protein CTD PMID:32407736 NCBI chr 2:208,566,385...208,577,147
Ensembl chr 2:208,566,385...208,577,146
Ensembl chr 2:208,566,385...208,577,146
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ATP5PF protein CTD PMID:32407736 NCBI chr11:24,286,806...24,294,419
Ensembl chr11:24,286,787...24,294,179
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
multiple interactions
ISO beauvericin results in decreased expression of BAX mRNA
[zearalenol co-treated with beauvericin] results in increased expression of BAX mRNA
CTD PMID:29203277 PMID:32956828 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
ISO beauvericin results in increased expression of BCL2 mRNA
[zearalenol co-treated with beauvericin] results in increased expression of BCL2 mRNA
CTD PMID:29203277 PMID:32956828 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 increases expression ISO beauvericin results in increased expression of BIRC2 mRNA CTD PMID:29203277 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO beauvericin results in increased expression of BIRC3 mRNA CTD PMID:29203277 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Btf3l4 basic transcription factor 3-like 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of BTF3L4 protein CTD PMID:32407736 NCBI chr 5:128,432,049...128,450,530
Ensembl chr 5:128,432,433...128,446,725
JBrowse link
G C1qtnf3 C1q and TNF related 3 decreases expression ISO beauvericin results in decreased expression of C1QTNF3 mRNA CTD PMID:29203277 NCBI chr 2:60,920,160...60,942,586
Ensembl chr 2:60,920,257...60,942,500
JBrowse link
G C1qtnf6 C1q and TNF related 6 increases expression ISO beauvericin results in increased expression of C1QTNF6 mRNA CTD PMID:29203277 NCBI chr 7:119,746,150...119,752,727
Ensembl chr 7:119,746,118...119,753,290
JBrowse link
G Caap1 caspase activity and apoptosis inhibitor 1 decreases expression ISO beauvericin results in decreased expression of CAAP1 mRNA CTD PMID:29203277 NCBI chr 5:113,479,416...113,532,961
Ensembl chr 5:113,480,547...113,532,878
JBrowse link
G Card11 caspase recruitment domain family, member 11 decreases expression ISO beauvericin results in decreased expression of CARD11 mRNA CTD PMID:29203277 NCBI chr12:15,700,600...15,844,512
Ensembl chr12:15,700,825...15,844,512
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
EXP
ISO
beauvericin results in increased activity of CASP3 protein
[zearalenol co-treated with beauvericin] results in increased expression of CASP3 mRNA
CTD PMID:25178661 PMID:32956828 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 increases activity EXP beauvericin results in increased activity of CASP7 protein CTD PMID:25178661 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 increases expression ISO beauvericin results in increased expression of CASP8 mRNA CTD PMID:29203277 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases expression ISO beauvericin results in increased expression of CASP9 mRNA CTD PMID:29203277 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 decreases expression ISO beauvericin results in decreased expression of CCAR2 mRNA CTD PMID:29203277 NCBI chr15:51,818,887...51,834,443
Ensembl chr15:51,818,897...51,834,030
JBrowse link
G Ccdc124 coiled-coil domain containing 124 decreases expression ISO beauvericin results in decreased expression of CCDC124 mRNA CTD PMID:29203277 NCBI chr16:20,317,446...20,323,265
Ensembl chr16:20,317,446...20,323,265
JBrowse link
G Ccdc180 coiled-coil domain containing 180 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CCDC180 protein CTD PMID:32407736 NCBI chr 5:61,467,799...61,542,675
Ensembl chr 5:61,474,000...61,542,653
JBrowse link
G Ccdc86 coiled-coil domain containing 86 decreases expression ISO beauvericin results in decreased expression of CCDC86 mRNA CTD PMID:29203277 NCBI chr 1:226,996,435...227,002,016
Ensembl chr 1:226,996,237...227,002,139
JBrowse link
G Ccng2 cyclin G2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CCNG2 mRNA CTD PMID:31100301 NCBI chr14:16,267,572...16,276,068
Ensembl chr14:16,267,573...16,276,068
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CCT5 protein CTD PMID:32407736 NCBI chr 2:84,667,578...84,678,730
Ensembl chr 2:84,667,633...84,678,790
JBrowse link
G Cd47 Cd47 molecule multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CD47 protein CTD PMID:32407736 NCBI chr11:53,511,485...53,575,754
Ensembl chr11:53,514,595...53,575,175
JBrowse link
G Cd81 Cd81 molecule multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CD81 protein CTD PMID:32407736 NCBI chr 1:216,237,663...216,253,460
Ensembl chr 1:216,237,697...216,253,311
JBrowse link
G Cdk2ap2 cyclin-dependent kinase 2 associated protein 2 decreases expression ISO beauvericin results in decreased expression of CDK2AP2 mRNA CTD PMID:29203277 NCBI chr 1:219,345,638...219,347,709
Ensembl chr 1:219,345,918...219,347,728
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CEBPB mRNA CTD PMID:31100301 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO beauvericin results in increased expression of CFLAR mRNA CTD PMID:29203277 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Chchd2 coiled-coil-helix-coiled-coil-helix domain containing 2 decreases expression ISO beauvericin results in decreased expression of CHCHD2 mRNA CTD PMID:29203277 NCBI chr 9:101,388,148...101,388,819
Ensembl chr 9:101,388,151...101,388,833
JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 decreases expression ISO beauvericin results in decreased expression of CIAPIN1 mRNA CTD PMID:29203277 NCBI chr19:10,596,923...10,612,414
Ensembl chr19:10,596,960...10,610,049
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CNP protein CTD PMID:32407736 NCBI chr10:88,490,798...88,497,357
Ensembl chr10:88,490,798...88,497,356
JBrowse link
G Coa6 cytochrome c oxidase assembly factor 6 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of COA6 protein CTD PMID:32407736 NCBI chr19:59,327,328...59,333,706
Ensembl chr19:59,328,960...59,331,192
JBrowse link
G Coro1c coronin 1C multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CORO1C protein CTD PMID:32407736 NCBI chr12:48,481,741...48,554,054
Ensembl chr12:48,481,750...48,554,052
JBrowse link
G Cotl1 coactosin-like F-actin binding protein 1 decreases expression ISO beauvericin results in decreased expression of COTL1 mRNA CTD PMID:29203277 NCBI chr19:52,465,074...52,499,433
Ensembl chr19:52,465,087...52,499,433
JBrowse link
G Cplane2 ciliogenesis and planar polarity effector 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CPLANE2 protein CTD PMID:32407736 NCBI chr 5:159,735,008...159,735,956
Ensembl chr 5:159,734,838...159,742,774
JBrowse link
G Cpne1 copine 1 decreases expression ISO beauvericin results in decreased expression of CPNE1 mRNA CTD PMID:29203277 NCBI chr 3:151,617,733...151,625,448
Ensembl chr 3:151,616,037...151,625,644
Ensembl chr 3:151,616,037...151,625,644
JBrowse link
G Crim1 cysteine rich transmembrane BMP regulator 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CRIM1 mRNA CTD PMID:31100301 NCBI chr 6:788,490...962,663
Ensembl chr 6:788,548...960,703
JBrowse link
G Csdc2 cold shock domain containing C2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CSDC2 protein CTD PMID:32407736 NCBI chr 7:123,168,811...123,183,336
Ensembl chr 7:123,168,811...123,183,335
JBrowse link
G Csk C-terminal Src kinase decreases expression ISO beauvericin results in decreased expression of CSK mRNA CTD PMID:29203277 NCBI chr 8:62,405,714...62,424,707
Ensembl chr 8:62,405,715...62,424,303
JBrowse link
G Ctps1 CTP synthase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CTPS1 protein CTD PMID:32407736 NCBI chr 5:139,475,934...139,505,065
Ensembl chr 5:139,475,934...139,505,065
JBrowse link
G Ctsd cathepsin D multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CTSD protein CTD PMID:32407736 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cyp4f39 cytochrome P450, family 4, subfamily f, polypeptide 39 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CYP4F22 protein CTD PMID:32407736 NCBI chr 7:14,435,024...14,514,960
Ensembl chr 7:14,441,476...14,515,212
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of DCXR protein CTD PMID:32407736 NCBI chr10:109,906,119...109,909,696
Ensembl chr10:109,906,815...109,909,715
JBrowse link
G Ddias DNA damage-induced apoptosis suppressor decreases expression ISO beauvericin results in decreased expression of DDIAS mRNA CTD PMID:29203277 NCBI chr 1:157,675,754...157,700,064
Ensembl chr 1:157,675,765...157,700,064
JBrowse link
G Ddx47 DEAD-box helicase 47 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of DDX47 protein CTD PMID:32407736 NCBI chr 4:168,775,134...168,787,594
Ensembl chr 4:168,775,111...168,787,730
JBrowse link
G Dhrs7 dehydrogenase/reductase 7 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of DHRS7 protein CTD PMID:32407736 NCBI chr 6:95,522,577...95,541,393
Ensembl chr 6:95,522,577...95,541,393
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression ISO beauvericin results in increased expression of EDEM1 mRNA CTD PMID:29203277 NCBI chr 4:140,886,644...140,918,654
Ensembl chr 4:140,886,545...140,915,779
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A decreases expression ISO beauvericin results in decreased expression of EIF5A mRNA CTD PMID:29203277 NCBI chr10:56,527,075...56,531,615
Ensembl chr10:56,527,085...56,531,483
JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 increases expression ISO beauvericin results in increased expression of FAIM2 mRNA CTD PMID:29203277 NCBI chr 7:141,158,769...141,185,781
Ensembl chr 7:141,157,963...141,185,710
JBrowse link
G Fmc1 formation of mitochondrial complex V assembly factor 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of FMC1 protein CTD PMID:32407736 NCBI chr 4:66,276,835...66,284,868
Ensembl chr 4:66,276,835...66,284,868
JBrowse link
G Gaa alpha glucosidase multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GAA protein CTD PMID:32407736 NCBI chr10:108,395,873...108,412,999
Ensembl chr10:108,395,860...108,413,059
JBrowse link
G Gna14 G protein subunit alpha 14 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GNA14 protein CTD PMID:32407736 NCBI chr 1:235,165,775...235,347,986
Ensembl chr 1:235,166,718...235,347,937
JBrowse link
G Gnai3 G protein subunit alpha i3 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of GNAI3 protein CTD PMID:32407736 NCBI chr 2:210,896,779...210,934,733
Ensembl chr 2:210,896,656...210,934,749
JBrowse link
G Gnb1 G protein subunit beta 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of GNB1 protein CTD PMID:32407736 NCBI chr 5:172,914,025...172,981,403
Ensembl chr 5:172,934,990...172,979,986
JBrowse link
G Golga1 golgin A1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GOLGA1 protein CTD PMID:32407736 NCBI chr 3:23,309,318...23,353,439
Ensembl chr 3:23,309,318...23,353,425
JBrowse link
G Gpnmb glycoprotein nmb multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of GPNMB protein CTD PMID:32407736 NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
JBrowse link
G Gpr18 G protein-coupled receptor 18 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GPR18 mRNA CTD PMID:31100301 NCBI chr15:108,323,157...108,326,907
Ensembl chr15:108,323,179...108,326,907
JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of HEXB protein CTD PMID:32407736 NCBI chr 2:27,983,925...28,003,260
Ensembl chr 2:27,984,117...28,003,186
JBrowse link
G Hist2h2be histone cluster 2 H2B family member E multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of HIST2H2BE protein CTD PMID:32407736 NCBI chr 2:198,360,837...198,363,399
Ensembl chr 2:198,360,998...198,361,378
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of HMGCS1 mRNA CTD PMID:31100301 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hnrnpm heterogeneous nuclear ribonucleoprotein M multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of HNRNPM protein CTD PMID:32407736 NCBI chr 7:18,516,253...18,554,536
Ensembl chr 7:18,516,512...18,554,227
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of HNRNPU protein CTD PMID:32407736 NCBI chr13:96,222,093...96,238,845
Ensembl chr13:96,225,912...96,238,572
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of HSPA5 mRNA CTD PMID:31100301 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Immt inner membrane mitochondrial protein multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of IMMT protein CTD PMID:32407736 NCBI chr 4:99,753,446...99,789,921
Ensembl chr 4:99,753,500...99,792,484
JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO beauvericin results in increased expression of INSIG1 mRNA CTD PMID:29203277 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Islr2 immunoglobulin superfamily containing leucine-rich repeat 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ISLR2 protein CTD PMID:32407736 NCBI chr 8:62,983,333...62,991,401
Ensembl chr 8:62,984,552...62,987,182
JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of ITGB1 protein CTD PMID:32407736 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Klf12 Kruppel-like factor 12 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KLF12 protein CTD PMID:32407736 NCBI chr15:84,316,986...84,748,549
Ensembl chr15:84,324,470...84,748,525
JBrowse link
G Kpnb1 karyopherin subunit beta 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KPNB1 protein CTD PMID:32407736 NCBI chr10:85,096,517...85,124,641
Ensembl chr10:85,093,841...85,124,644
JBrowse link
G Krt16 keratin 16 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KRT16 protein CTD PMID:32407736 NCBI chr10:88,149,210...88,152,167
Ensembl chr10:88,149,345...88,152,064
JBrowse link
G Krt27 keratin 27 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of KRT27 protein CTD PMID:32407736 NCBI chr10:87,256,434...87,261,717
Ensembl chr10:87,256,434...87,261,717
JBrowse link
G Krt5 keratin 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of KRT5 protein CTD PMID:32407736 NCBI chr 7:143,320,142...143,324,536
Ensembl chr 7:143,316,920...143,453,546
JBrowse link
G Krt76 keratin 76 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KRT76 protein CTD PMID:32407736 NCBI chr 7:143,488,668...143,497,108
Ensembl chr 7:143,488,684...143,497,108
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of LAMP2 protein CTD PMID:32407736 NCBI chr  X:124,722,628...124,766,079
Ensembl chr  X:124,722,628...124,766,044
JBrowse link
G Lat linker for activation of T cells decreases expression ISO beauvericin results in decreased expression of LAT mRNA CTD PMID:29203277 NCBI chr 1:197,765,644...197,770,669
Ensembl chr 1:197,765,644...197,770,669
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation EXP beauvericin results in decreased phosphorylation of MAPK1 protein CTD PMID:25178661 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation EXP beauvericin results in decreased phosphorylation of MAPK3 protein CTD PMID:25178661 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Matn4 matrilin 4 decreases expression ISO beauvericin results in decreased expression of MATN4 mRNA CTD PMID:29203277 NCBI chr 3:160,838,632...160,853,650
Ensembl chr 3:160,838,632...160,853,650
JBrowse link
G Mavs mitochondrial antiviral signaling protein increases expression ISO beauvericin results in increased expression of MAVS mRNA CTD PMID:29203277 NCBI chr 3:123,776,147...123,790,572
Ensembl chr 3:123,776,181...123,790,567
JBrowse link
G Med6 mediator complex subunit 6 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of MED6 protein CTD PMID:32407736 NCBI chr 6:105,302,558...105,316,024
Ensembl chr 6:105,302,558...105,316,024
JBrowse link
G Moap1 modulator of apoptosis 1 increases expression ISO beauvericin results in increased expression of MOAP1 mRNA CTD PMID:29203277 NCBI chr 6:126,620,597...126,622,532
Ensembl chr 6:126,620,602...126,622,532
JBrowse link
G Mrpl12 mitochondrial ribosomal protein L12 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of MRPL12 mRNA
[beauvericin co-treated with enniatins] results in decreased expression of MRPL12 mRNA
CTD PMID:29203277 PMID:31100301 NCBI chr10:109,658,032...109,662,535
Ensembl chr10:109,658,032...109,662,535
JBrowse link
G Mrpl4 mitochondrial ribosomal protein L4 decreases expression ISO beauvericin results in decreased expression of MRPL4 mRNA CTD PMID:29203277 NCBI chr 8:22,021,213...22,027,228
Ensembl chr 8:22,021,213...22,027,228
JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of ATP6 mRNA
[beauvericin co-treated with enniatins] results in increased expression of ATP6 mRNA
CTD PMID:29203277 PMID:31100301 NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of ATP8 mRNA
[beauvericin co-treated with enniatins] affects the expression of ATP8 mRNA
CTD PMID:29203277 PMID:31100301 NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I multiple interactions
decreases expression
ISO [beauvericin co-treated with enniatins] affects the expression of COX1 mRNA
beauvericin results in decreased expression of COX1 mRNA
CTD PMID:31100301 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III decreases expression ISO beauvericin results in decreased expression of COX3 mRNA CTD PMID:29203277 PMID:31100301 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b decreases expression ISO beauvericin results in decreased expression of CYTB mRNA CTD PMID:29203277 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of ND2 mRNA
[beauvericin co-treated with enniatins] results in decreased expression of ND2 mRNA
CTD PMID:29203277 PMID:31100301 NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942
JBrowse link
G Mt-nd3 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of ND3 mRNA
[beauvericin co-treated with enniatins] results in increased expression of ND3 mRNA
CTD PMID:29203277 PMID:31100301 NCBI chr MT:9,451...9,798
Ensembl chr MT:9,451...9,798
JBrowse link
G Mt-nd4 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of ND4 mRNA
[beauvericin co-treated with enniatins] results in increased expression of ND4 mRNA
CTD PMID:29203277 PMID:31100301 NCBI chr MT:10,160...11,537
Ensembl chr MT:10,160...11,537
JBrowse link
G Mt-nd4l mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L decreases expression ISO beauvericin results in decreased expression of ND4L mRNA CTD PMID:29203277 PMID:31100301 NCBI chr MT:9,870...10,166
Ensembl chr MT:9,870...10,166
JBrowse link
G Mt-nd5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of ND5 mRNA
[beauvericin co-treated with enniatins] results in decreased expression of ND5 mRNA
CTD PMID:29203277 PMID:31100301 NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565
JBrowse link
G Mtrf1l mitochondrial translation release factor 1 like multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of MTRF1L protein CTD PMID:32407736 NCBI chr 1:42,475,791...42,485,999
Ensembl chr 1:42,475,792...42,486,035
JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NARS1 protein CTD PMID:32407736 NCBI chr18:59,986,350...60,002,644
Ensembl chr18:59,986,360...60,002,569
JBrowse link
G Nars2 asparaginyl-tRNA synthetase 2, mitochondrial multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NARS2 protein CTD PMID:32407736 NCBI chr 1:161,922,132...162,035,817
Ensembl chr 1:161,922,141...162,034,700
JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NDRG1 protein CTD PMID:32407736 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A increases expression ISO beauvericin results in increased expression of NLRP1 mRNA CTD PMID:29203277 NCBI chr10:57,692,474...57,747,608
Ensembl chr10:57,692,474...57,822,498
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 increases expression ISO beauvericin results in increased expression of NOD1 mRNA CTD PMID:29203277 NCBI chr 4:85,123,965...85,175,206
Ensembl chr 4:85,123,960...85,174,951
JBrowse link
G Nol3 nucleolar protein 3 increases expression ISO beauvericin results in increased expression of NOL3 mRNA CTD PMID:29203277 NCBI chr19:37,232,567...37,236,668
Ensembl chr19:37,235,001...37,236,649
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of NQO1 mRNA CTD PMID:31100301 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nudt1 nudix hydrolase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NUDT1 protein CTD PMID:32407736 NCBI chr12:16,391,578...16,398,771
Ensembl chr12:16,391,578...16,395,029
JBrowse link
G Oga O-GlcNAcase increases expression ISO beauvericin results in increased expression of OGA mRNA CTD PMID:29203277 NCBI chr 1:265,506,752...265,542,452
Ensembl chr 1:265,507,451...265,542,276
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase increases expression ISO beauvericin results in increased expression of OGT mRNA CTD PMID:29203277 NCBI chr  X:71,540,870...71,585,906
Ensembl chr  X:71,528,988...71,585,908
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of OSGIN1 mRNA CTD PMID:31100301 NCBI chr19:52,056,808...52,085,491
Ensembl chr19:52,077,109...52,085,496
JBrowse link
G Ostc oligosaccharyltransferase complex non-catalytic subunit multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of OSTC protein CTD PMID:32407736 NCBI chr 2:235,816,328...235,831,651
Ensembl chr 2:235,816,336...235,831,670
JBrowse link
G Parvg parvin, gamma multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PARVG protein CTD PMID:32407736 NCBI chr 7:125,288,081...125,307,587
Ensembl chr 7:125,288,081...125,306,976
JBrowse link
G Pawr pro-apoptotic WT1 regulator decreases expression ISO beauvericin results in decreased expression of PAWR mRNA CTD PMID:29203277 NCBI chr 7:51,273,764...51,353,700
Ensembl chr 7:51,273,771...51,353,068
JBrowse link
G Pdcd11 programmed cell death 11 decreases expression ISO beauvericin results in decreased expression of PDCD11 mRNA CTD PMID:29203277 NCBI chr 1:266,866,931...266,908,042
Ensembl chr 1:266,866,931...266,908,042
JBrowse link
G Pdcd2 programmed cell death 2 decreases expression ISO beauvericin results in decreased expression of PDCD2 mRNA CTD PMID:29203277 NCBI chr 1:57,512,968...57,518,458
Ensembl chr 1:57,512,968...57,518,458
JBrowse link
G Pdcd2l programmed cell death 2-like increases expression ISO beauvericin results in increased expression of PDCD2L mRNA CTD PMID:29203277 NCBI chr 1:90,045,468...90,057,756
Ensembl chr 1:90,045,509...90,057,923
JBrowse link
G Pdcd4 programmed cell death 4 decreases expression ISO beauvericin results in decreased expression of PDCD4 mRNA CTD PMID:29203277 NCBI chr 1:274,616,625...274,648,204
Ensembl chr 1:274,625,224...274,648,204
JBrowse link
G Pdcd5 programmed cell death 5 increases expression ISO beauvericin results in increased expression of PDCD5 mRNA CTD PMID:29203277 NCBI chr 1:91,173,473...91,178,801
Ensembl chr 1:91,173,473...91,178,801
Ensembl chr 1:91,173,473...91,178,801
JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein increases expression ISO beauvericin results in increased expression of PDCD6IP mRNA CTD PMID:29203277 NCBI chr 8:121,916,233...121,973,145
Ensembl chr 8:121,916,185...121,973,125
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 decreases expression ISO beauvericin results in decreased expression of PDIA4 mRNA CTD PMID:29203277 NCBI chr 4:77,470,636...77,489,535
Ensembl chr 4:77,470,636...77,489,535
JBrowse link
G Pfn1 profilin 1 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of PFN1 mRNA
[beauvericin co-treated with enniatins] results in increased expression of PFN1 protein
CTD PMID:29203277 PMID:32407736 NCBI chr10:57,273,003...57,275,708
Ensembl chr10:57,273,005...57,275,708
JBrowse link
G Pgam1 phosphoglycerate mutase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PGAM1 protein CTD PMID:32407736 NCBI chr 1:261,158,204...261,165,814
Ensembl chr 1:261,158,261...261,165,808
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PGK1 protein CTD PMID:32407736 NCBI chr  X:77,263,399...77,279,373
Ensembl chr  X:77,263,359...77,279,367
JBrowse link
G Phgdh phosphoglycerate dehydrogenase multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PHGDH protein CTD PMID:32407736 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
G Phka2 phosphorylase kinase regulatory subunit alpha 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PHKA2 protein CTD PMID:32407736 NCBI chr  X:35,970,650...36,926,616 JBrowse link
G Pidd1 p53-induced death domain protein 1 decreases expression ISO beauvericin results in decreased expression of PIDD1 mRNA CTD PMID:29203277 NCBI chr 1:214,418,751...214,423,959
Ensembl chr 1:214,419,240...214,423,881
Ensembl chr 1:214,419,240...214,423,881
JBrowse link
G Plk1 polo-like kinase 1 decreases expression ISO beauvericin results in decreased expression of PLK1 mRNA CTD PMID:29203277 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989
JBrowse link
G Pls3 plastin 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PLS3 protein CTD PMID:32407736 NCBI chr  X:119,030,311...119,124,268
Ensembl chr  X:119,030,419...119,124,250
JBrowse link
G Ppa1 inorganic pyrophosphatase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PPA1 protein CTD PMID:32407736 NCBI chr20:31,265,519...31,292,451
Ensembl chr20:31,265,483...31,310,674
JBrowse link
G Ppan peter pan homolog decreases expression ISO beauvericin results in decreased expression of PPAN mRNA CTD PMID:29203277 NCBI chr 8:21,905,865...21,909,845
Ensembl chr 8:21,905,865...21,909,842
JBrowse link
G Ppib peptidylprolyl isomerase B decreases expression ISO beauvericin results in decreased expression of PPIB mRNA CTD PMID:29203277 NCBI chr 8:71,719,681...71,725,538
Ensembl chr 8:71,719,563...71,725,562
JBrowse link
G Ppp1r14b protein phosphatase 1, regulatory (inhibitor) subunit 14B decreases expression ISO beauvericin results in decreased expression of PPP1R14B mRNA CTD PMID:29203277 NCBI chr 1:222,229,835...222,231,945
Ensembl chr 1:222,229,835...222,231,944
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PPT1 protein CTD PMID:32407736 NCBI chr 5:140,538,260...140,558,163
Ensembl chr 5:140,538,260...140,558,162
JBrowse link
G Prkca protein kinase C, alpha multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PRKCA protein CTD PMID:32407736 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Psma5 proteasome 20S subunit alpha 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PSMA5 protein CTD PMID:32407736 NCBI chr 2:211,050,344...211,073,706
Ensembl chr 2:211,050,360...211,073,714
JBrowse link
G Psme4 proteasome activator subunit 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PSME4 protein CTD PMID:32407736 NCBI chr14:115,166,165...115,269,041
Ensembl chr14:115,166,416...115,269,056
JBrowse link
G Ptges3 prostaglandin E synthase 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PTGES3 protein CTD PMID:32407736 NCBI chr 7:2,479,267...2,497,024
Ensembl chr 7:2,479,311...2,497,013
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PTPRC protein CTD PMID:32407736 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
G Rab11fip5 RAB11 family interacting protein 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of RAB11FIP5 protein CTD PMID:32407736 NCBI chr 4:117,113,067...117,154,495
Ensembl chr 4:117,115,076...117,153,907
JBrowse link
G Rab5a RAB5A, member RAS oncogene family multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RAB5A protein CTD PMID:32407736 NCBI chr 9:5,910...6,065 JBrowse link
G Rac3 Rac family small GTPase 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RAC3 protein CTD PMID:32407736 NCBI chr10:109,903,920...109,906,596
Ensembl chr10:109,904,259...109,906,232
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RAP1A protein CTD PMID:32407736 NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187
JBrowse link
G Relt RELT, TNF receptor decreases expression ISO beauvericin results in decreased expression of RELT mRNA CTD PMID:29203277 NCBI chr 1:165,884,407...165,902,022
Ensembl chr 1:165,884,407...165,901,923
JBrowse link
G Rp2 RP2 activator of ARL3 GTPase multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RP2 protein CTD PMID:32407736 NCBI chr  X:2,066,298...2,116,661
Ensembl chr  X:2,064,486...2,116,656
JBrowse link
G Rpl37a ribosomal protein L37a multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RPL37A protein CTD PMID:32407736 NCBI chr 9:80,002,892...80,004,995 JBrowse link
G Rpl5 ribosomal protein L5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RPL5 protein CTD PMID:32407736 NCBI chr14:2,860,963...2,867,397
Ensembl chr14:2,860,965...2,867,397
JBrowse link
G Rpl8 ribosomal protein L8 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of RPL8 protein CTD PMID:32407736 NCBI chr 7:117,967,608...117,969,886
Ensembl chr 7:118,507,224...118,509,256
Ensembl chr 3:118,507,224...118,509,256
Ensembl chr 7:118,507,224...118,509,256
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RXRA protein CTD PMID:32407736 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Scml2 Scm polycomb group protein like 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SCML2 protein CTD PMID:32407736 NCBI chr  X:35,305,235...35,431,271
Ensembl chr  X:35,305,236...35,431,164
JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SDF2L1 protein CTD PMID:32407736 NCBI chr11:88,122,271...88,124,513
Ensembl chr11:88,122,271...88,124,513
JBrowse link
G Sdr42e2 short chain dehydrogenase/reductase family 42E, member 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SDR42E2 protein CTD PMID:32407736 NCBI chr 1:190,756,747...190,769,213 JBrowse link
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component decreases expression ISO beauvericin results in decreased expression of SEC13 mRNA CTD PMID:29203277 NCBI chr 4:145,686,186...145,699,577
Ensembl chr 4:145,686,193...145,699,577
JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor decreases expression ISO beauvericin results in decreased expression of SIVA1 mRNA CTD PMID:29203277 NCBI chr 6:137,209,999...137,214,379
Ensembl chr 6:137,210,052...137,214,388
JBrowse link
G Slc1a5 solute carrier family 1 member 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SLC1A5 protein CTD PMID:32407736 NCBI chr 1:78,710,686...78,724,789
Ensembl chr 1:78,710,539...78,724,794
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SLC2A1 protein CTD PMID:32407736 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc3a2 solute carrier family 3 member 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SLC3A2 protein CTD PMID:32407736 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092
JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SNRPD2 protein CTD PMID:32407736 NCBI chr 1:80,057,140...80,059,990
Ensembl chr 1:80,056,755...80,059,996
JBrowse link
G Snrpd3 small nuclear ribonucleoprotein D3 polypeptide multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SNRPD3 protein CTD PMID:32407736 NCBI chr20:14,080,562...14,095,644
Ensembl chr20:14,080,565...14,095,181
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase decreases activity EXP beauvericin results in decreased activity of SRC protein CTD PMID:25178661 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Srm spermidine synthase decreases expression ISO beauvericin results in decreased expression of SRM mRNA CTD PMID:29203277 NCBI chr 5:165,405,168...165,408,325
Ensembl chr 5:165,405,168...165,408,320
Ensembl chr 3:165,405,168...165,408,320
JBrowse link
G Srsf7 serine and arginine rich splicing factor 7 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SRSF7 protein CTD PMID:32407736 NCBI chr 6:2,879,312...2,886,505
Ensembl chr 6:2,880,518...2,886,465
JBrowse link
G Srxn1 sulfiredoxin 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SRXN1 mRNA CTD PMID:31100301 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Ssbp1 single stranded DNA binding protein 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SSBP1 protein CTD PMID:32407736 NCBI chr 4:68,634,844...68,645,112
Ensembl chr 4:68,634,929...68,645,172
JBrowse link
G Tbc1d2b TBC1 domain family, member 2B multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TBC1D2B protein CTD PMID:32407736 NCBI chr 8:97,577,551...97,647,072
Ensembl chr 8:97,577,565...97,647,072
JBrowse link
G Tcn2 transcobalamin 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TCN2 protein CTD PMID:32407736 NCBI chr14:84,173,992...84,189,299
Ensembl chr14:84,174,138...84,189,266
JBrowse link
G Tcp11l1 t-complex 11 like 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TCP11L1 protein CTD PMID:32407736 NCBI chr 3:94,621,433...94,657,467
Ensembl chr 3:94,624,071...94,657,377
JBrowse link
G Tcp11l2 t-complex 11 like 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TCP11L2 protein CTD PMID:32407736 NCBI chr 7:24,859,048...24,893,907
Ensembl chr 7:24,859,050...24,885,775
JBrowse link
G Thyn1 thymocyte nuclear protein 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of THYN1 protein CTD PMID:32407736 NCBI chr 8:28,045,093...28,053,974
Ensembl chr 8:28,045,093...28,054,040
JBrowse link
G Timm9 translocase of inner mitochondrial membrane 9 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TIMM9 protein CTD PMID:32407736 NCBI chr 6:93,549,484...93,562,314
Ensembl chr 6:93,549,484...93,562,314
JBrowse link
G Tk1 thymidine kinase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TK1 protein CTD PMID:32407736 NCBI chr10:106,817,556...106,828,888
Ensembl chr10:106,817,601...106,828,884
JBrowse link
G Tmem263 transmembrane protein 263 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TMEM263 protein CTD PMID:32407736 NCBI chr 7:24,647,083...24,668,381
Ensembl chr 7:24,647,083...24,668,250
JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression ISO beauvericin results in decreased expression of TNFSF10 mRNA CTD PMID:29203277 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tomm22 translocase of outer mitochondrial membrane 22 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TOMM22 protein CTD PMID:32407736 NCBI chr 7:120,901,934...120,903,684
Ensembl chr 7:120,901,934...120,903,684
JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TOMM7 protein CTD PMID:32407736 NCBI chr 4:7,835,949...7,842,790
Ensembl chr 4:7,835,949...7,842,789
JBrowse link
G Tuba1b tubulin, alpha 1B multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBA1B protein CTD PMID:32407736 NCBI chr 7:140,614,746...140,617,721
Ensembl chr 7:140,614,752...140,617,721
JBrowse link
G Tubb3 tubulin, beta 3 class III multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB3 protein CTD PMID:32407736 NCBI chr19:56,220,759...56,229,813
Ensembl chr19:56,220,755...56,229,813
JBrowse link
G Tubb4a tubulin, beta 4A class IVa multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB4A protein CTD PMID:32407736 NCBI chr 9:9,961,020...9,968,420
Ensembl chr 9:9,961,021...9,968,486
JBrowse link
G Tubb4b tubulin, beta 4B class IVb multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB4B protein CTD PMID:32407736 NCBI chr 3:2,441,585...2,444,369
Ensembl chr 3:2,441,733...2,444,281
JBrowse link
G Tubb5 tubulin, beta 5 class I multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB protein CTD PMID:32407736 NCBI chr20:3,422,448...3,426,420
Ensembl chr20:3,422,461...3,426,371
JBrowse link
G Txnip thioredoxin interacting protein increases expression ISO beauvericin results in increased expression of TXNIP mRNA CTD PMID:29203277 NCBI chr 2:198,683,168...198,686,971
Ensembl chr 2:198,683,159...198,686,974
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of UCP2 mRNA CTD PMID:31100301 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Ucp3 uncoupling protein 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of UCP3 mRNA CTD PMID:31100301 NCBI chr 1:165,482,912...165,495,895
Ensembl chr 1:165,482,155...165,496,206
JBrowse link
G Ybx1 Y box binding protein 1 decreases expression ISO beauvericin results in decreased expression of YBX1 mRNA CTD PMID:29203277 NCBI chr 5:138,319,754...138,336,721
Ensembl chr 5:138,319,762...138,336,475
JBrowse link
G Ybx3 Y box binding protein 3 decreases expression ISO beauvericin results in decreased expression of YBX3 mRNA CTD PMID:29203277 NCBI chr 4:165,606,819...165,630,041
Ensembl chr 4:165,606,819...165,630,118
JBrowse link
G Ykt6 YKT6 v-SNARE homolog multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of YKT6 protein CTD PMID:32407736 NCBI chr14:86,196,018...86,207,057
Ensembl chr14:86,195,892...86,205,712
JBrowse link
carbon monoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases activity EXP Carbon Monoxide results in increased activity of ABCC2 protein CTD PMID:13678533 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions
increases expression
EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of AKT1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of NOS3 protein]; [Carbon Monoxide results in increased expression of ADIPOQ protein] inhibits the reaction [TNF protein results in increased activity of CASP3 protein]; [Carbon Monoxide results in increased expression of ADIPOQ protein] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; [Carbon Monoxide results in increased expression of ADIPOQ protein] inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; [Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of AKT1 protein; [Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of NOS3 protein
[Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased expression of PECAM1 protein; Carbon Monoxide results in increased expression of ADIPOQ protein
CTD PMID:19356108 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adm adrenomedullin increases expression EXP Carbon Monoxide results in increased expression of ADM mRNA; Carbon Monoxide results in increased expression of ADM protein CTD PMID:10666155 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of AGR2 mRNA CTD PMID:29621558 NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714
JBrowse link
G Agt angiotensinogen decreases response to substance ISO AGT protein results in decreased susceptibility to Carbon Monoxide CTD PMID:18174886 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation
ISO
EXP
AKT1 protein affects the reaction [Carbon Monoxide results in increased localization of NRF1 protein]; Carbon Monoxide inhibits the reaction [Doxorubicin results in decreased phosphorylation of AKT1 protein]; Carbon Monoxide results in increased phosphorylation of and results in increased activity of AKT1 protein; CAT protein inhibits the reaction [Carbon Monoxide results in increased phosphorylation of AKT1 protein]
Carbon Monoxide inhibits the reaction [IL18 protein results in decreased phosphorylation of AKT1 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of AKT1 protein]; [Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of AKT1 protein; Carbon Monoxide results in increased phosphorylation of and results in increased activity of AKT1 protein; CAT protein inhibits the reaction [Carbon Monoxide results in increased phosphorylation of and results in increased activity of AKT1 protein]
CTD PMID:17179207 PMID:18037988 PMID:18215737 PMID:18845810 PMID:19356108 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alad aminolevulinate dehydratase increases activity
multiple interactions
EXP Carbon Monoxide results in increased activity of ALAD protein
Carbon Monoxide inhibits the reaction [[Phenobarbital co-treated with bromobenzene] results in decreased activity of ALAD protein]
CTD PMID:1032310 PMID:6740708 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Areg amphiregulin multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of AREG mRNA CTD PMID:29621558 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Bach1 BTB domain and CNC homolog 1 decreases phosphorylation ISO Carbon Monoxide results in decreased phosphorylation of BACH1 protein CTD PMID:18845810 NCBI chr11:27,364,913...27,398,713
Ensembl chr11:27,364,916...27,398,842
Ensembl chr11:27,364,916...27,398,842
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO Carbon Monoxide inhibits the reaction [Doxorubicin results in decreased phosphorylation of BAD protein] CTD PMID:18037988 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bcl2a1 BCL2-related protein A1 multiple interactions ISO BCL2A1 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]; MAPK14 protein affects the reaction [BCL2A1 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]] CTD PMID:11880364 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
decreases expression
EXP Carbon Monoxide results in decreased expression of and results in decreased secretion of BDNF protein
Carbon Monoxide results in decreased expression of BDNF mRNA
CTD PMID:27113706 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions ISO BIRC3 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]; MAPK14 protein affects the reaction [BIRC3 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]] CTD PMID:11880364 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
EXP
ISO
[Carbon Monoxide results in increased expression of ADIPOQ protein] inhibits the reaction [TNF protein results in increased activity of CASP3 protein]; Carbon Monoxide inhibits the reaction [Carbon Tetrachloride results in increased activity of CASP3 protein]; Carbon Monoxide results in increased cleavage of and results in increased activity of CASP3 protein; Hemin inhibits the reaction [Carbon Monoxide results in increased cleavage of and results in increased activity of CASP3 protein]; tin protoporphyrin IX inhibits the reaction [Hemin inhibits the reaction [Carbon Monoxide results in increased cleavage of and results in increased activity of CASP3 protein]]
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP3 mRNA
Carbon Monoxide results in increased activity of CASP3 protein
CTD PMID:17173083 PMID:19356108 PMID:19520142 PMID:25562542 PMID:31268311 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 increases activity EXP Carbon Monoxide results in increased activity of CASP7 protein CTD PMID:25562542 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 increases activity
multiple interactions
EXP
ISO
Carbon Monoxide results in increased activity of CASP8 protein
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP8 mRNA
CTD PMID:25562542 PMID:31268311 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions
EXP
ISO
Carbon Monoxide results in increased activity of CASP9 protein
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP9 mRNA
CTD PMID:25562542 PMID:31268311 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions ISO
EXP
CAT protein inhibits the reaction [Carbon Monoxide results in increased localization of NFE2L2 protein]; CAT protein inhibits the reaction [Carbon Monoxide results in increased phosphorylation of AKT1 protein]
CAT protein inhibits the reaction [Carbon Monoxide promotes the reaction [NRF1 protein binds to TFAM promoter]]; CAT protein inhibits the reaction [Carbon Monoxide results in increased phosphorylation of and results in increased activity of AKT1 protein]
CTD PMID:17179207 PMID:18845810 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl1 C-C motif chemokine ligand 1 multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of CCL1 mRNA CTD PMID:29621558 NCBI chr10:69,534,976...69,537,836
Ensembl chr10:69,534,933...69,537,882
JBrowse link
G Cd86 CD86 molecule decreases expression EXP Carbon Monoxide results in decreased expression of CD86 protein CTD PMID:12201358 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Clca1 chloride channel accessory 1 multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of CLCA1 mRNA CTD PMID:29621558 NCBI chr 2:250,897,980...250,923,711
Ensembl chr 2:250,897,969...250,923,744
JBrowse link
G Col11a1 collagen type XI alpha 1 chain multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of COL11A1 mRNA CTD PMID:29621558 NCBI chr 2:216,863,423...217,056,523
Ensembl chr 2:216,863,428...217,056,523
JBrowse link
G Crp C-reactive protein increases expression ISO Carbon Monoxide results in increased expression of CRP protein CTD PMID:18629312 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of CXCL11 mRNA CTD PMID:29621558 NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP Carbon Monoxide inhibits the reaction [CYP1A1 protein results in increased reduction of sodium chromate(VI)] CTD PMID:1903091 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO Carbon Monoxide promotes the reaction [1-ethynylpyrene results in increased expression of CYP1B1 mRNA] CTD PMID:10581206 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP Carbon Monoxide inhibits the reaction [CYP2B1 protein results in increased reduction of sodium chromate(VI)] CTD PMID:1903091 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity
multiple interactions
ISO
EXP
Carbon Monoxide results in decreased activity of CYP2E1 protein
Carbon Monoxide inhibits the reaction [CYP2E1 protein results in increased reduction of sodium chromate(VI)]
CTD PMID:1903091 PMID:15036350 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Duox2 dual oxidase 2 increases expression
decreases expression
EXP Carbon Monoxide results in increased expression of DUOX2 mRNA
Carbon Monoxide results in decreased expression of DUOX2 protein
CTD PMID:29223502 NCBI chr 3:114,218,187...114,237,808
Ensembl chr 3:114,218,193...114,235,933
JBrowse link
G Edn1 endothelin 1 increases expression
multiple interactions
EXP
ISO
Carbon Monoxide results in increased expression of EDN1 mRNA; Carbon Monoxide results in increased expression of EDN1 protein
Carbon Monoxide deficiency promotes the reaction [HMOX2 mutant form results in increased expression of EDN1 protein]
CTD PMID:11781074 PMID:12969895 PMID:20197249 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO Carbon Monoxide inhibits the reaction [Lipopolysaccharides results in increased expression of EGR1 mRNA]; Carbon Monoxide inhibits the reaction [Lipopolysaccharides results in increased expression of EGR1 protein]; UCP2 protein promotes the reaction [Carbon Monoxide inhibits the reaction [Lipopolysaccharides results in increased expression of EGR1 protein]] CTD PMID:22046279 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Epo erythropoietin increases expression EXP Carbon Monoxide results in increased expression of EPO mRNA; Carbon Monoxide results in increased expression of EPO protein CTD PMID:9263988 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression EXP Carbon Monoxide results in increased expression of ERO1A mRNA CTD PMID:12752442 NCBI chr15:19,619,947...19,655,381
Ensembl chr15:19,619,973...19,655,381
JBrowse link
G Fgb fibrinogen beta chain multiple interactions ISO FGB gene SNP affects the reaction [Carbon Monoxide results in increased expression of IL6 protein] CTD PMID:19750100 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
JBrowse link
G Foxp3 forkhead box P3 multiple interactions ISO [Air Pollutants results in increased abundance of Carbon Monoxide] which results in increased methylation of FOXP3 promoter CTD PMID:29317916 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Gabpa GA binding protein transcription factor subunit alpha increases expression
multiple interactions
ISO
EXP
Carbon Monoxide results in increased expression of GABPA mRNA
Carbon Monoxide results in increased expression of GABPA protein
1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [Carbon Monoxide results in increased expression of GABPA protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carbon Monoxide results in increased expression of GABPA protein]; Carbon Monoxide promotes the reaction [GABPA protein binds to TFAM promoter]
CTD PMID:17179207 NCBI chr11:24,293,845...24,322,822
Ensembl chr11:24,263,281...24,322,815
JBrowse link
G Gata4 GATA binding protein 4 multiple interactions ISO Carbon Monoxide inhibits the reaction [Doxorubicin results in decreased activity of GATA4 protein] CTD PMID:18037988 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Gpr182 G protein-coupled receptor 182 increases expression EXP Carbon Monoxide results in increased expression of GPR182 mRNA CTD PMID:10666155 NCBI chr 7:71,044,786...71,048,713
Ensembl chr 7:71,045,543...71,048,383
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions ISO Carbon Monoxide inhibits the reaction [Doxorubicin results in decreased expression of GPX4 protein] CTD PMID:18037988 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation
ISO Carbon Monoxide inhibits the reaction [Doxorubicin results in decreased phosphorylation of GSK3B protein]
Carbon Monoxide results in increased phosphorylation of GSK3B protein
CTD PMID:18037988 PMID:18845810 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases chemical synthesis
increases expression
increases activity
ISO
EXP
Carbon Monoxide inhibits the reaction [Doxorubicin results in decreased expression of HMOX1 protein]; Carbon Monoxide inhibits the reaction [IFNG protein results in decreased expression of HMOX1 protein]; HMOX1 protein affects the reaction [Carbon Monoxide results in increased secretion of IL10 protein]; HMOX1 protein promotes the reaction [Carbon Monoxide results in increased expression of IL22 mRNA]; NFE2L2 protein affects the reaction [Carbon Monoxide results in increased activity of HMOX1 protein]; NFE2L2 protein affects the reaction [Carbon Monoxide results in increased expression of HMOX1 mRNA]
HMOX1 protein results in increased chemical synthesis of Carbon Monoxide
[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein; [RELA protein co-treated with REL protein] inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]; BCL2A1 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]; BIRC3 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]; MAPK14 protein affects the reaction [BCL2A1 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]]; MAPK14 protein affects the reaction [BIRC3 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]]; RELA protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]
Carbon Monoxide results in increased expression of HMOX1 protein
Edaravone promotes the reaction [Carbon Monoxide results in increased expression of HMOX1 protein]; Hemin promotes the reaction [Carbon Monoxide results in increased activity of HMOX1 protein]; Hemin promotes the reaction [Carbon Monoxide results in increased expression of HMOX1 protein]; tin protoporphyrin IX inhibits the reaction [Carbon Monoxide results in increased activity of HMOX1 protein]
CTD PMID:11880364 PMID:16365149 PMID:18037988 PMID:18845810 PMID:19520142 PMID:21444764 PMID:25348283 PMID:29165873 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hmox2 heme oxygenase 2 multiple interactions
affects chemical synthesis
affects abundance
EXP Carbon Monoxide deficiency promotes the reaction [HMOX2 mutant form results in increased expression of EDN1 protein]
HMOX2 protein affects the chemical synthesis of Carbon Monoxide
HMOX2 protein affects the abundance of Carbon Monoxide
CTD PMID:11342580 PMID:12969895 NCBI chr10:10,990,034...11,035,493
Ensembl chr10:10,990,034...11,035,484
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP
ISO
[Carbon Monoxide results in increased expression of ADIPOQ protein] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]
Carbon Monoxide inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]
CTD PMID:19356108 PMID:19608869 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of IFNG protein; Carbon Monoxide inhibits the reaction [IFNG protein promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein]]; Carbon Monoxide inhibits the reaction [IFNG protein results in decreased expression of HMOX1 protein] CTD PMID:16365149 PMID:29621558 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression
ISO
EXP
Carbon Monoxide promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]; HMOX1 protein affects the reaction [Carbon Monoxide results in increased secretion of IL10 protein]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Carbon Monoxide results in increased expression of IL10 protein]; iodopravadoline inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Carbon Monoxide results in increased expression of IL10 protein]]
Carbon Monoxide results in increased expression of IL10 mRNA
CTD PMID:21444764 PMID:31732924 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12b interleukin 12B multiple interactions ISO Carbon Monoxide inhibits the reaction [IFNG protein promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein]] CTD PMID:16365149 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il13 interleukin 13 multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of IL13 mRNA CTD PMID:29621558 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il17a interleukin 17A multiple interactions ISO [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of IL17A protein CTD PMID:29621558 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il18 interleukin 18 decreases response to substance
multiple interactions
ISO Carbon Monoxide results in decreased susceptibility to IL18 protein
Carbon Monoxide inhibits the reaction [IL18 protein results in decreased phosphorylation of AKT1 protein]; Carbon Monoxide inhibits the reaction [IL18 protein results in increased expression of PTEN protein]
CTD PMID:18215737 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1b interleukin 1 beta decreases expression
multiple interactions
increases expression
ISO
EXP
Carbon Monoxide results in decreased expression of IL1B protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Carbon Monoxide results in increased expression of IL1B protein]; iodopravadoline inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Carbon Monoxide results in increased expression of IL1B protein]]
CTD PMID:21444764 PMID:31732924 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression
multiple interactions
EXP Carbon Monoxide results in increased expression of IL1RL1 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Carbon Monoxide results in increased expression of IL1RL1 protein]; iodopravadoline inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Carbon Monoxide results in increased expression of IL1RL1 protein]]
CTD PMID:31732924 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il33 interleukin 33 multiple interactions
increases expression
EXP (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Carbon Monoxide results in increased expression of IL33 protein]; AM 251 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Carbon Monoxide results in increased expression of IL33 protein]] CTD PMID:31732924 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Il4 interleukin 4 decreases expression
multiple interactions
ISO
EXP
Carbon Monoxide results in decreased expression of IL4 protein
[Carbon Monoxide co-treated with (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone] results in increased expression of IL4 protein; iodopravadoline inhibits the reaction [[Carbon Monoxide co-treated with (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone] results in increased expression of IL4 protein]
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of IL4 protein
CTD PMID:21444764 PMID:29621558 PMID:31732924 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased secretion of IL6 protein; Carbon Monoxide inhibits the reaction [TNF protein results in increased expression of IL6 protein]; FGB gene SNP affects the reaction [Carbon Monoxide results in increased expression of IL6 protein]; IL6 gene SNP affects the reaction [Carbon Monoxide results in increased expression of IL6 protein] CTD PMID:18629312 PMID:19608869 PMID:19750100 PMID:31268311 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Irf8 interferon regulatory factor 8 decreases activity ISO Carbon Monoxide results in decreased activity of IRF8 protein CTD PMID:16365149 NCBI chr19:54,314,859...54,336,643
Ensembl chr19:54,314,865...54,336,640
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO Carbon Monoxide inhibits the reaction [NFE2L2 protein binds to KEAP1 protein] CTD PMID:18845810 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO MAPK14 protein affects the reaction [BCL2A1 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]]; MAPK14 protein affects the reaction [BIRC3 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]] CTD PMID:11880364 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mir1224 microRNA 1224 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR1224 mRNA CTD PMID:31268311 NCBI chr11:83,992,628...83,992,712
Ensembl chr11:83,992,628...83,992,712
JBrowse link
G Mir186 microRNA 186 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR186 mRNA CTD PMID:31268311 NCBI chr 2:263,873,759...263,873,844
Ensembl chr 2:263,873,759...263,873,844
JBrowse link
G Mir21 microRNA 21 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR21 mRNA CTD PMID:31268311 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mir342 microRNA 342 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR342 mRNA CTD PMID:31268311 NCBI chr 6:132,561,169...132,561,267
Ensembl chr 6:132,561,169...132,561,267
JBrowse link
G Mir374b microRNA 374b multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR374B mRNA CTD PMID:31268311 NCBI chr  X:74,443,648...74,443,715
Ensembl chr  X:74,443,648...74,443,715
JBrowse link
G Mir615 microRNA 615 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR615 mRNA CTD PMID:31268311 NCBI chr 7:144,629,019...144,629,110
Ensembl chr 7:144,629,019...144,629,110
JBrowse link
G Mir93 microRNA 93 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR93 mRNA CTD PMID:31268311 NCBI chr12:19,307,543...19,307,629
Ensembl chr12:19,307,543...19,307,629
JBrowse link
G Mirlet7i microRNA let-7i multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIRLET7I mRNA CTD PMID:31268311 NCBI chr 7:66,802,731...66,802,815
Ensembl chr 7:66,802,732...66,802,821
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO Carbon Monoxide results in increased expression of MMP9 mRNA CTD PMID:20197249 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions EXP [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Carbon Monoxide] results in increased expression of MRC1 protein; iodopravadoline inhibits the reaction [[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Carbon Monoxide] results in increased expression of MRC1 protein] CTD PMID:31732924 NCBI chr17:81,352,700...81,433,743
Ensembl chr17:81,352,700...81,433,743
JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions ISO Carbon Monoxide inhibits the reaction [Oxygen deficiency results in increased expression of NDRG1 mRNA]; Carbon Monoxide inhibits the reaction [Oxygen deficiency results in increased expression of NDRG1 protein] CTD PMID:11006124 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
increases expression
increases localization
decreases phosphorylation
ISO
EXP
Carbon Monoxide inhibits the reaction [NFE2L2 protein binds to KEAP1 protein]; Carbon Monoxide promotes the reaction [NFE2L2 protein binds to NRF1 promoter]; CAT protein inhibits the reaction [Carbon Monoxide results in increased localization of NFE2L2 protein]; NFE2L2 protein affects the reaction [Carbon Monoxide results in increased activity of HMOX1 protein]; NFE2L2 protein affects the reaction [Carbon Monoxide results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [Carbon Monoxide results in increased expression of SOD2 mRNA]
Carbon Monoxide results in increased expression of NFE2L2 protein
Edaravone promotes the reaction [Carbon Monoxide results in increased expression of NFE2L2 protein]
Carbon Monoxide results in increased expression of NFE2L2 mRNA
Carbon Monoxide results in decreased phosphorylation of NFE2L2 protein
CTD PMID:18845810 PMID:25348283 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [RELA protein co-treated with REL protein] inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]; BCL2A1 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]; BIRC3 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]; MAPK14 protein affects the reaction [BCL2A1 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]]; MAPK14 protein affects the reaction [BIRC3 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]]; RELA protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]] CTD PMID:11880364 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Ngf nerve growth factor affects expression
multiple interactions
EXP Carbon Monoxide affects the expression of NGF mRNA
Carbon Monoxide results in decreased expression of and affects the secretion of NGF protein
CTD PMID:27113706 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
ISO
EXP
Carbon Monoxide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; PPARG protein promotes the reaction [Carbon Monoxide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]]
Carbon Monoxide results in decreased expression of NOS2 protein
CTD PMID:12201358 PMID:22046279 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of NOS3 protein]; [Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of NOS3 protein CTD PMID:19356108 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nppa natriuretic peptide A increases expression EXP Carbon Monoxide results in increased expression of NPPA mRNA CTD PMID:11781074 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nrf1 nuclear respiratory factor 1 multiple interactions
increases expression
increases localization
ISO
EXP
AKT1 protein affects the reaction [Carbon Monoxide results in increased localization of NRF1 protein]; Carbon Monoxide promotes the reaction [NFE2L2 protein binds to NRF1 promoter]
Carbon Monoxide results in increased expression of NRF1 protein
1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [Carbon Monoxide results in increased expression of NRF1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carbon Monoxide promotes the reaction [NRF1 protein binds to PPARGC1A protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carbon Monoxide results in increased expression of NRF1 protein]; Carbon Monoxide promotes the reaction [NRF1 protein binds to PPARGC1A protein]; Carbon Monoxide promotes the reaction [NRF1 protein binds to TFAM promoter]; CAT protein inhibits the reaction [Carbon Monoxide promotes the reaction [NRF1 protein binds to TFAM promoter]]
Carbon Monoxide results in increased expression of NRF1 mRNA
CTD PMID:17179207 PMID:18845810 NCBI chr 4:57,335,732...57,445,317
Ensembl chr 4:57,378,069...57,445,341
JBrowse link
G Ntf3 neurotrophin 3 decreases expression
multiple interactions
EXP Carbon Monoxide results in decreased expression of NTF3 mRNA
Carbon Monoxide results in decreased expression of and results in decreased secretion of NTF3 protein
CTD PMID:27113706 NCBI chr 4:158,636,883...158,705,886
Ensembl chr 4:158,636,884...158,705,886
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 increases expression EXP [Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased expression of PECAM1 protein CTD PMID:19356108 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pla2g7 phospholipase A2 group VII affects expression ISO Carbon Monoxide affects the expression of PLA2G7 CTD PMID:21356620 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
JBrowse link
G Polg DNA polymerase gamma, catalytic subunit increases expression ISO