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ONTOLOGY REPORT - ANNOTATIONS


Term:EC 1.14.14.14 (aromatase) inhibitor
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Accession:CHEBI:50790 term browser browse the term
Definition:An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor which interferes with the action of aromatase (EC 1.14.14.14) and so reduces production of estrogenic steroid hormones.
Synonyms:related_synonym: EC 1.14.14.14 (aromatase) inhibitors;   EC 1.14.14.14 inhibitor;   EC 1.14.14.14 inhibitors;   aromatase inhibitor;   aromatase inhibitors;   estrogen synthase inhibitor;   estrogen synthase inhibitors;   estrogen synthetase inhibitor;   estrogen synthetase inhibitors;   oestrogen synthase inhibitor;   oestrogen synthase inhibitors;   oestrogen synthetase inhibitor;   oestrogen synthetase inhibitors
 xref: Wikipedia:Aromatase_inhibitor


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alpha-naphthoflavone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 JBrowse link 11 25,342,119 25,350,938 RGD:6480464
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Arnt aryl hydrocarbon receptor nuclear translocator JBrowse link 2 196,594,178 196,651,486 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bmp15 bone morphogenetic protein 15 JBrowse link X 17,016,831 17,021,894 RGD:6480464
G Bpgm bisphosphoglycerate mutase JBrowse link 4 61,912,210 61,940,697 RGD:6480464
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:6480464
G Calr calreticulin JBrowse link 19 25,956,771 25,961,666 RGD:6480464
G Casp12 caspase 12 JBrowse link 8 2,658,892 2,686,160 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Ccl1 C-C motif chemokine ligand 1 JBrowse link 10 69,534,976 69,537,836 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:6480464
G Cd9 CD9 molecule JBrowse link 4 157,977,163 158,010,091 RGD:6480464
G Cdc25c cell division cycle 25C JBrowse link 18 27,528,768 27,550,316 RGD:6480464
G Cdh13 cadherin 13 JBrowse link 19 50,848,793 51,971,618 RGD:6480464
G Cdk1 cyclin-dependent kinase 1 JBrowse link 20 20,576,341 20,591,510 RGD:6480464
G Cdk2 cyclin dependent kinase 2 JBrowse link 7 3,124,953 3,132,533 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:6480464
G Csf2 colony stimulating factor 2 JBrowse link 10 39,602,089 39,604,070 RGD:6480464
G Ctsd cathepsin D JBrowse link 1 215,541,570 215,553,446 RGD:6480464
G Cygb cytoglobin JBrowse link 10 105,618,325 105,628,091 RGD:6480464
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 JBrowse link 7 116,248,759 116,255,205 RGD:6480464
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 1 266,422,127 266,429,947 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:6480464
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 JBrowse link 3 168,097,484 168,111,920 RGD:6480464
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 JBrowse link 1 257,676,172 258,004,428 RGD:6480464
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 JBrowse link 1 83,933,974 83,947,804 RGD:6480464
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 JBrowse link 5 119,546,458 119,564,843 RGD:6480464
G Dazl deleted in azoospermia-like JBrowse link 9 12,633,983 12,651,017 RGD:6480464
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:6480464
G Ddr2 discoidin domain receptor tyrosine kinase 2 JBrowse link 13 88,311,639 88,436,561 RGD:6480464
G Ddx4 DEAD-box helicase 4 JBrowse link 2 44,447,610 44,504,263 RGD:6480464
G Ddx5 DEAD-box helicase 5 JBrowse link 10 94,979,759 94,988,461 RGD:6480464
G Dll1 delta like canonical Notch ligand 1 JBrowse link 1 57,318,621 57,326,732 RGD:6480464
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 JBrowse link 4 2,711,329 2,774,969 RGD:6480464
G Dusp5 dual specificity phosphatase 5 JBrowse link 1 274,245,184 274,258,595 RGD:6480464
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:6480464
G Egln1 egl-9 family hypoxia-inducible factor 1 JBrowse link 19 57,660,194 57,701,158 RGD:6480464
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha JBrowse link 6 102,048,372 102,073,041 RGD:6480464
G Eno1 enolase 1 JBrowse link 5 167,288,223 167,299,610 RGD:6480464
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 JBrowse link 7 94,479,931 94,563,086 RGD:6480464
G Ervfrd-1 endogenous retrovirus group FRD member 1, envelope JBrowse link 12 25,161,130 25,168,182 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:6480464
G Esrra estrogen related receptor, alpha JBrowse link 1 222,168,729 222,178,842 RGD:6480464
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:6480464
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:6480464
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:6480464
G Flg filaggrin JBrowse link 2 193,565,401 193,574,297 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Foxn3 forkhead box N3 JBrowse link 6 123,183,720 123,577,719 RGD:6480464
G Foxo3 forkhead box O3 JBrowse link 20 46,428,078 46,519,156 RGD:6480464
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:6480464
G Fshr follicle stimulating hormone receptor JBrowse link 6 12,796,383 12,997,817 RGD:6480464
G Gdf9 growth differentiation factor 9 JBrowse link 10 38,782,519 38,793,238 RGD:6480464
G Gpi glucose-6-phosphate isomerase JBrowse link 1 90,063,411 90,091,287 RGD:6480464
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:6480464
G Hk1 hexokinase 1 JBrowse link 20 31,911,460 31,979,780 RGD:6480464
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:6480464
G Hspa8 heat shock protein family A (Hsp70) member 8 JBrowse link 8 44,989,401 44,993,261 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:6480464
G Igfbp4 insulin-like growth factor binding protein 4 JBrowse link 10 86,950,555 86,962,563 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Itgb8 integrin subunit beta 8 JBrowse link 6 147,089,280 147,172,846 RGD:6480464
G Jag1 jagged canonical Notch ligand 1 JBrowse link 3 130,079,361 130,114,781 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Krt14 keratin 14 JBrowse link 10 88,118,029 88,122,233 RGD:6480464
G Ldha lactate dehydrogenase A JBrowse link 1 102,900,288 102,909,713 RGD:6480464
G Lhcgr luteinizing hormone/choriogonadotropin receptor JBrowse link 6 12,493,182 12,554,482 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:6480464
G Mmp1 matrix metallopeptidase 1 JBrowse link 8 5,703,206 5,723,593 RGD:6480464
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:6480464
G Mmp3 matrix metallopeptidase 3 JBrowse link 8 5,676,608 5,698,579 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Mt1 metallothionein 1 JBrowse link 19 11,301,991 11,303,007 RGD:6480464
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:6480464
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:6480464
G Myog myogenin JBrowse link 13 51,126,459 51,129,048 RGD:6480464
G Ncf1 neutrophil cytosolic factor 1 JBrowse link 12 25,497,104 25,506,300 RGD:6480464
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 JBrowse link 9 69,919,863 69,953,182 RGD:6480464
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 JBrowse link 3 79,721,686 79,728,863 RGD:6480464
G Nfatc1 nuclear factor of activated T-cells 1 JBrowse link 18 77,203,517 77,322,690 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Notch2 notch receptor 2 JBrowse link 2 200,187,184 200,320,403 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 JBrowse link 13 89,585,072 89,591,278 RGD:6480464
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 JBrowse link 2 5,569,954 5,579,894 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:6480464
G Pfkm phosphofructokinase, muscle JBrowse link 7 139,702,066 139,722,132 RGD:6480464
G Pgk1 phosphoglycerate kinase 1 JBrowse link X 77,263,399 77,279,373 RGD:6480464
G Pgm1 phosphoglucomutase 1 JBrowse link 5 118,743,632 118,803,055 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Pkm pyruvate kinase M1/2 JBrowse link 8 64,480,963 64,502,957 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:6480464
G Prdm1 PR/SET domain 1 JBrowse link 20 49,464,921 49,556,623 RGD:6480464
G Prkcb protein kinase C, beta JBrowse link 1 192,233,569 192,575,339 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Ptk2 protein tyrosine kinase 2 JBrowse link 7 114,436,419 114,611,317 RGD:6480464
G Rack1 receptor for activated C kinase 1 JBrowse link 10 34,149,717 34,155,198 RGD:6480464
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Serpinb2 serpin family B member 2 JBrowse link 13 27,449,907 27,463,015 RGD:6480464
G Slc2a1 solute carrier family 2 member 1 JBrowse link 5 138,154,677 138,182,897 RGD:6480464
G Slc5a5 solute carrier family 5 member 5 JBrowse link 16 20,297,414 20,307,401 RGD:6480464
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:6480464
G Sp1 Sp1 transcription factor JBrowse link 7 144,014,173 144,044,635 RGD:6480464
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:6480464
G Stat5b signal transducer and activator of transcription 5B JBrowse link 10 88,686,207 88,712,313 RGD:6480464
G Tcf7 transcription factor 7 JBrowse link 10 37,616,033 37,646,027 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase JBrowse link 2 157,316,293 157,342,979 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tnfsf11 TNF superfamily member 11 JBrowse link 15 60,482,527 60,512,704 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Tpi1 triosephosphate isomerase 1 JBrowse link 4 157,328,375 157,331,905 RGD:6480464
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464
G Wapl WAPL cohesin release factor JBrowse link 16 11,029,325 11,108,867 RGD:6480464
aminoglutethimide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acp1 acid phosphatase 1 JBrowse link 6 49,836,064 49,851,714 RGD:6480464
G Anp32b acidic nuclear phosphoprotein 32 family member B JBrowse link 5 62,070,709 62,094,633 RGD:6480464
G Basp1 brain abundant, membrane attached signal protein 1 JBrowse link 2 77,586,424 77,632,626 RGD:6480464
G Bcap31 B-cell receptor-associated protein 31 JBrowse link X 157,094,365 157,126,397 RGD:6480464
G Cct4 chaperonin containing TCP1 subunit 4 JBrowse link 14 107,767,392 107,780,270 RGD:6480464
G Cct6a chaperonin containing TCP1 subunit 6A JBrowse link 12 30,491,584 30,501,813 RGD:6480464
G Cct7 chaperonin containing TCP1 subunit 7 JBrowse link 4 117,235,023 117,252,265 RGD:6480464
G Comt catechol-O-methyltransferase JBrowse link 11 86,715,981 86,735,630 RGD:6480464
G Cuta cutA divalent cation tolerance homolog JBrowse link 20 5,532,024 5,533,640 RGD:6480464
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 8 62,798,317 62,809,848 RGD:6480464
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 1 266,422,127 266,429,947 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:6480464
G Gatd3a glutamine amidotransferase like class 1 domain containing 3A JBrowse link 20 11,244,353 11,252,450 RGD:6480464
G Gns glucosamine (N-acetyl)-6-sulfatase JBrowse link 7 63,467,027 63,501,054 RGD:6480464
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:6480464
G Gsn gelsolin JBrowse link 3 14,456,106 14,508,922 RGD:6480464
G H1f2 H1.2 linker histone, cluster member JBrowse link 17 43,638,938 43,640,445 RGD:6480464
G H2az1 H2A.Z variant histone 1 JBrowse link 2 243,105,224 243,107,333 RGD:6480464
G H2bc12 H2B clustered histone 12 JBrowse link 17 44,527,421 44,527,801 RGD:6480464
G Hmgb2 high mobility group box 2 JBrowse link 16 36,077,615 36,080,191 RGD:6480464
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 JBrowse link 10 35,872,619 35,879,911 RGD:6480464
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 JBrowse link 10 88,987,558 88,989,758 RGD:6480464
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 JBrowse link X 21,696,796 21,699,241 RGD:6480464
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 JBrowse link 18 44,810,462 44,897,677 RGD:6480464
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 JBrowse link 13 88,288,116 88,308,019 RGD:6480464
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:6480464
G Hyou1 hypoxia up-regulated 1 JBrowse link 8 48,699,796 48,711,912 RGD:6480464
G Impdh2 inosine monophosphate dehydrogenase 2 JBrowse link 8 117,346,983 117,351,619 RGD:6480464
G Lhb luteinizing hormone subunit beta JBrowse link 1 101,409,992 101,413,725 RGD:6480464
G Lmna lamin A/C JBrowse link 2 187,842,884 187,863,552 RGD:6480464
G Lmnb2 lamin B2 JBrowse link 7 11,657,870 11,676,936 RGD:6480464
G LOC680322 similar to Histone H2A type 1 JBrowse link 17 44,527,990 44,528,557 RGD:6480464
G LOC684762 similar to CG31613-PA JBrowse link 17 43,776,018 43,776,779 RGD:6480464
G Mcm3 minichromosome maintenance complex component 3 JBrowse link 9 26,914,057 26,932,201 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Myo18a myosin XVIIIa JBrowse link 10 64,979,770 65,080,535 RGD:6480464
G Npm3 nucleophosmin/nucleoplasmin, 3 JBrowse link 1 265,504,105 265,506,080 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464
G Nup210 nucleoporin 210 JBrowse link 4 122,643,952 122,741,322 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Pitpnb phosphatidylinositol transfer protein, beta JBrowse link 12 51,279,194 51,341,752 RGD:6480464
G Ppp1ca protein phosphatase 1 catalytic subunit alpha JBrowse link 1 219,439,953 219,443,570 RGD:6480464
G Prdx3 peroxiredoxin 3 JBrowse link 1 282,238,774 282,251,193 RGD:6480464
G Psmb4 proteasome 20S subunit beta 4 JBrowse link 2 196,043,546 196,046,320 RGD:6480464
G Rtraf RNA transcription, translation and transport factor JBrowse link 15 4,882,925 4,893,890 RGD:6480464
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:6480464
G Ssb small RNA binding exonuclease protection factor La JBrowse link 3 56,092,425 56,102,008 RGD:6480464
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:6480464
G Tpt1 tumor protein, translationally-controlled 1 JBrowse link 15 57,891,680 57,894,504 RGD:6480464
G Ubc ubiquitin C JBrowse link 12 36,638,457 36,642,734 RGD:6480464
G Ube2k ubiquitin-conjugating enzyme E2K JBrowse link 14 44,289,247 44,348,691 RGD:6480464
G Wdr1 WD repeat domain 1 JBrowse link 14 76,990,014 77,023,739 RGD:6480464
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta JBrowse link 6 43,463,294 43,493,816 RGD:6480464
anastrozole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cycs cytochrome c, somatic JBrowse link 4 80,331,226 80,333,326 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:6480464
G Gja1 gap junction protein, alpha 1 JBrowse link 20 37,876,650 37,889,097 RGD:6480464
G Lhb luteinizing hormone subunit beta JBrowse link 1 101,409,992 101,413,725 RGD:6480464
G Mki67 marker of proliferation Ki-67 JBrowse link 1 207,993,895 208,020,454 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
exemestane term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcg4 ATP binding cassette subfamily G member 4 JBrowse link 8 48,604,915 48,626,219 RGD:6480464
G Adcyap1r1 ADCYAP receptor type I JBrowse link 4 85,662,809 85,711,696 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:6480464
G Cd83 CD83 molecule JBrowse link 17 24,416,651 24,435,790 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G Dab2 DAB adaptor protein 2 JBrowse link 2 55,747,353 55,768,848 RGD:6480464
G Ebf1 EBF transcription factor 1 JBrowse link 10 23,654,849 24,051,627 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Gpc2 glypican 2 JBrowse link 12 19,593,041 19,599,374 RGD:6480464
G Hoxd11 homeobox D11 JBrowse link 3 61,604,256 61,606,874 RGD:6480464
G Inpp5k inositol polyphosphate-5-phosphatase K JBrowse link 10 63,775,639 63,796,879 RGD:6480464
G Ints4 integrator complex subunit 4 JBrowse link 1 162,447,692 162,511,350 RGD:6480464
G Kif13b kinesin family member 13B JBrowse link 15 48,030,837 48,192,932 RGD:6480464
G Klk7 kallikrein-related peptidase 7 JBrowse link 1 99,749,991 99,754,723 RGD:6480464
G Metrn meteorin, glial cell differentiation regulator JBrowse link 10 15,164,439 15,166,457 RGD:6480464
G Mki67 marker of proliferation Ki-67 JBrowse link 1 207,993,895 208,020,454 RGD:6480464
G Mybl2 MYB proto-oncogene like 2 JBrowse link 3 159,421,638 159,450,087 RGD:6480464
G Myo9b myosin IXb JBrowse link 16 19,669,373 19,754,065 RGD:6480464
G Ostm1 osteoclastogenesis associated transmembrane protein 1 JBrowse link 20 47,394,979 47,430,304 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Plcg2 phospholipase C, gamma 2 JBrowse link 19 50,039,410 50,173,543 RGD:6480464
G RGD1565616 RGD1565616 JBrowse link 3 123,243,873 123,376,458 RGD:6480464
G Rnf123 ring finger protein 123 JBrowse link 8 116,829,050 116,857,050 RGD:6480464
G Rrp12 ribosomal RNA processing 12 homolog JBrowse link 1 261,106,768 261,140,416 RGD:6480464
G Slc13a4 solute carrier family 13 member 4 JBrowse link 4 62,796,732 62,841,053 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
G Tbc1d17 TBC1 domain family, member 17 JBrowse link 1 100,836,993 100,845,216 RGD:6480464
G Tff1 trefoil factor 1 JBrowse link 20 9,892,124 9,895,984 RGD:6480464
G Tnfrsf14 TNF receptor superfamily member 14 JBrowse link 5 172,328,259 172,337,221 RGD:6480464
G Triobp TRIO and F-actin binding protein JBrowse link 7 120,173,892 120,237,145 RGD:6480464
formestane term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 8 62,798,317 62,809,848 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:6480464
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 JBrowse link 10 88,987,558 88,989,758 RGD:6480464
glycitein term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca1 ATP binding cassette subfamily A member 1 JBrowse link 5 69,857,717 69,983,042 RGD:6480464
G Acsl3 acyl-CoA synthetase long-chain family member 3 JBrowse link 9 84,569,601 84,593,565 RGD:6480464
G Add2 adducin 2 JBrowse link 4 117,691,294 117,887,556 RGD:6480464
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:6480464
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 JBrowse link 8 77,640,234 77,719,488 RGD:6480464
G Anpep alanyl aminopeptidase, membrane JBrowse link 1 141,561,364 141,604,249 RGD:6480464
G Arhgdia Rho GDP dissociation inhibitor alpha JBrowse link 10 109,754,012 109,757,506 RGD:6480464
G Atoh8 atonal bHLH transcription factor 8 JBrowse link 4 100,067,341 100,099,517 RGD:6480464
G Atp6v0a2 ATPase H+ transporting V0 subunit a2 JBrowse link 12 37,368,321 37,398,233 RGD:6480464
G Baz1a bromodomain adjacent to zinc finger domain, 1A JBrowse link 6 75,793,223 75,873,854 RGD:6480464
G Bckdk branched chain ketoacid dehydrogenase kinase JBrowse link 1 199,351,628 199,356,299 RGD:6480464
G Bpgm bisphosphoglycerate mutase JBrowse link 4 61,912,210 61,940,697 RGD:6480464
G Cabp5 calcium binding protein 5 JBrowse link 1 75,693,216 75,706,069 RGD:6480464
G Cacybp calcyclin binding protein JBrowse link 13 77,948,771 77,959,089 RGD:6480464
G Casp8ap2 caspase 8 associated protein 2 JBrowse link 5 47,853,699 47,891,147 RGD:6480464
G Ccna2 cyclin A2 JBrowse link 2 123,274,727 123,282,266 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Cd200r1 CD200 receptor 1 JBrowse link 11 60,848,161 60,882,470 RGD:6480464
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Cybrd1 cytochrome b reductase 1 JBrowse link 3 57,718,496 57,745,749 RGD:6480464
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 8 62,798,317 62,809,848 RGD:6480464
G Dennd2d DENN domain containing 2D JBrowse link 2 209,097,894 209,116,978 RGD:6480464
G Dnmt1 DNA methyltransferase 1 JBrowse link 8 21,922,515 21,968,495 RGD:6480464
G Dnmt3a DNA methyltransferase 3 alpha JBrowse link 6 28,205,375 28,346,052 RGD:6480464
G Dock3 dedicator of cyto-kinesis 3 JBrowse link 8 115,627,282 115,982,260 RGD:6480464
G Dpp9 dipeptidyl peptidase 9 JBrowse link 9 10,846,493 10,882,560 RGD:6480464
G Edrf1 erythroid differentiation regulatory factor 1 JBrowse link 1 205,706,023 205,743,676 RGD:6480464
G Efhd1 EF-hand domain family, member D1 JBrowse link 9 94,362,249 94,408,884 RGD:6480464
G Epha1 Eph receptor A1 JBrowse link 4 71,749,100 71,763,681 RGD:6480464
G Espn espin JBrowse link 5 169,293,356 169,331,338 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:6480464
G Fam171a2 family with sequence similarity 171, member A2 JBrowse link 10 90,383,111 90,393,476 RGD:6480464
G Fam180a family with sequence similarity 180, member A JBrowse link 4 62,845,054 62,860,361 RGD:6480464
G Fam210b family with sequence similarity 210, member B JBrowse link 3 170,354,109 170,364,265 RGD:6480464
G Fam241b family with sequence similarity 241 member B JBrowse link 20 31,734,297 31,736,115 RGD:6480464
G Fgd6 FYVE, RhoGEF and PH domain containing 6 JBrowse link 7 34,951,878 35,063,006 RGD:6480464
G Fhl2 four and a half LIM domains 2 JBrowse link 9 49,920,611 49,994,906 RGD:6480464
G Fmn2 formin 2 JBrowse link 13 92,569,256 92,887,302 RGD:6480464
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 JBrowse link 16 8,127,599 8,178,101 RGD:6480464
G Gng5 G protein subunit gamma 5 JBrowse link 2 252,359,976 252,368,473 RGD:6480464
G Hipk4 homeodomain interacting protein kinase 4 JBrowse link 1 84,328,114 84,338,486 RGD:6480464
G Hmcn1 hemicentin 1 JBrowse link 13 67,799,791 68,360,664 RGD:6480464
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 RGD:6480464
G Ifrd2 interferon-related developmental regulator 2 JBrowse link 8 116,343,096 116,348,318 RGD:6480464
G Il6r interleukin 6 receptor JBrowse link 2 189,196,180 189,255,987 RGD:6480464
G Irf2bp1 interferon regulatory factor 2 binding protein 1 JBrowse link 1 79,911,516 79,914,217 RGD:6480464
G Isg20l2 interferon stimulated exonuclease gene 20-like 2 JBrowse link 2 187,302,192 187,311,677 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Kcng2 potassium voltage-gated channel modifier subfamily G member 2 JBrowse link 18 76,808,294 76,880,742 RGD:6480464
G Kdm5a lysine demethylase 5A JBrowse link 4 152,892,388 152,972,196 RGD:6480464
G Kitlg KIT ligand JBrowse link 7 42,269,784 42,351,054 RGD:6480464
G Knstrn kinetochore-localized astrin/SPAG5 binding protein JBrowse link 3 110,618,256 110,638,024 RGD:6480464
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 JBrowse link 5 152,964,294 152,987,286 RGD:6480464
G Lmod1 leiomodin 1 JBrowse link 13 52,147,099 52,189,835 RGD:6480464
G Lrg1 leucine-rich alpha-2-glycoprotein 1 JBrowse link 9 10,952,424 10,954,664 RGD:6480464
G Lsr lipolysis stimulated lipoprotein receptor JBrowse link 1 89,383,515 89,399,041 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mmp3 matrix metallopeptidase 3 JBrowse link 8 5,676,608 5,698,579 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Mrpl33 mitochondrial ribosomal protein L33 JBrowse link 6 26,130,278 26,138,498 RGD:6480464
G Mtmr11 myotubularin related protein 11 JBrowse link 2 198,301,666 198,311,787 RGD:6480464
G Myof myoferlin JBrowse link 1 256,585,410 256,734,727 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 JBrowse link 7 142,899,358 142,920,216 RGD:6480464
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 JBrowse link 3 22,998,900 23,020,441 RGD:6480464
G Nrip1 nuclear receptor interacting protein 1 JBrowse link 11 14,658,225 14,742,478 RGD:6480464
G Olfml3 olfactomedin-like 3 JBrowse link 2 206,219,419 206,222,248 RGD:6480464
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:6480464
G Pdlim2 PDZ and LIM domain 2 JBrowse link 15 51,843,562 51,856,785 RGD:6480464
G Pnn pinin, desmosome associated protein JBrowse link 6 80,159,364 80,167,677 RGD:6480464
G Pou4f2 POU class 4 homeobox 2 JBrowse link 19 33,160,180 33,163,821 RGD:6480464
G Prkaca protein kinase cAMP-activated catalytic subunit alpha JBrowse link 19 25,095,089 25,118,869 RGD:6480464
G Prpf40a pre-mRNA processing factor 40 homolog A JBrowse link 3 38,680,583 38,741,570 RGD:6480464
G Pspc1 paraspeckle component 1 JBrowse link 15 36,946,914 37,030,273 RGD:6480464
G Pth1r parathyroid hormone 1 receptor JBrowse link 8 118,984,531 119,012,803 RGD:6480464
G Rassf5 Ras association domain family member 5 JBrowse link 13 47,956,754 48,022,333 RGD:6480464
G Rgs22 regulator of G-protein signaling 22 JBrowse link 7 74,783,009 74,902,049 RGD:6480464
G Rps6ka3 ribosomal protein S6 kinase A3 JBrowse link X 37,469,736 37,576,055 RGD:6480464
G S1pr3 sphingosine-1-phosphate receptor 3 JBrowse link 17 13,799,383 13,812,877 RGD:6480464
G Selplg selectin P ligand JBrowse link 12 48,577,905 48,579,196 RGD:6480464
G Sgpp1 sphingosine-1-phosphate phosphatase 1 JBrowse link 6 98,675,324 98,696,492 RGD:6480464
G Siglec10 sialic acid binding Ig-like lectin 10 JBrowse link 1 98,512,663 98,521,736 RGD:6480464
G Slc12a2 solute carrier family 12 member 2 JBrowse link 18 52,917,124 52,985,281 RGD:6480464
G Slc16a1 solute carrier family 16 member 1 JBrowse link 2 207,108,552 207,129,352 RGD:6480464
G Slc22a8 solute carrier family 22 member 8 JBrowse link 1 224,799,444 224,818,482 RGD:6480464
G Snx30 sorting nexin family member 30 JBrowse link 5 77,052,445 77,161,964 RGD:6480464
G Sp1 Sp1 transcription factor JBrowse link 7 144,014,173 144,044,635 RGD:6480464
G Ssc5d scavenger receptor cysteine rich family member with 5 domains JBrowse link 1 72,443,750 72,462,293 RGD:6480464
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:6480464
G Stc1 stanniocalcin 1 JBrowse link 15 50,891,137 50,901,791 RGD:6480464
G Styxl1 serine/threonine/tyrosine interacting-like 1 JBrowse link 12 23,954,563 23,987,155 RGD:6480464
G Sumo1 small ubiquitin-like modifier 1 JBrowse link 9 66,453,428 66,483,614 RGD:6480464
G Tacr3 tachykinin receptor 3 JBrowse link 2 240,021,152 240,118,971 RGD:6480464
G Tc2n tandem C2 domains, nuclear JBrowse link 6 125,437,767 125,601,408 RGD:6480464
G Tnfaip6 TNF alpha induced protein 6 JBrowse link 3 37,545,238 37,564,704 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Tp53i11 tumor protein p53 inducible protein 11 JBrowse link 3 82,081,838 82,097,064 RGD:6480464
G Uchl1 ubiquitin C-terminal hydrolase L1 JBrowse link 14 43,133,224 43,143,942 RGD:6480464
G Vcpip1 valosin containing protein interacting protein 1 JBrowse link 5 9,231,180 9,257,821 RGD:6480464
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:6480464
G Wdr66 WD repeat domain 66 JBrowse link 12 38,708,915 38,781,598 RGD:6480464
letrozole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Angpt2 angiopoietin 2 JBrowse link 16 75,966,480 76,016,147 RGD:6480464
G Angpt4 angiopoietin 4 JBrowse link 3 147,421,724 147,455,670 RGD:6480464
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Ccnd2 cyclin D2 JBrowse link 4 159,674,885 159,697,207 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Cycs cytochrome c, somatic JBrowse link 4 80,331,226 80,333,326 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G Cyp51 cytochrome P450, family 51 JBrowse link 4 27,175,564 27,194,018 RGD:6480464
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:6480464
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 JBrowse link 16 68,954,860 68,968,248 RGD:6480464
G Elk1 ETS transcription factor ELK1 JBrowse link X 1,287,875 1,304,822 RGD:6480464
G Epas1 endothelial PAS domain protein 1 JBrowse link 6 10,306,508 10,385,239 RGD:6480464
G Fgf22 fibroblast growth factor 22 JBrowse link 7 12,829,785 12,831,675 RGD:6480464
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:6480464
G Gja1 gap junction protein, alpha 1 JBrowse link 20 37,876,650 37,889,097 RGD:6480464
G Grb2 growth factor receptor bound protein 2 JBrowse link 10 104,193,953 104,263,071 RGD:6480464
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Lhb luteinizing hormone subunit beta JBrowse link 1 101,409,992 101,413,725 RGD:6480464
G Lif LIF, interleukin 6 family cytokine JBrowse link 14 84,482,652 84,500,574 RGD:6480464
G Lifr LIF receptor subunit alpha JBrowse link 2 56,424,910 56,489,346 RGD:6480464
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:6480464
G Map2k2 mitogen activated protein kinase kinase 2 JBrowse link 7 11,458,971 11,478,520 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mki67 marker of proliferation Ki-67 JBrowse link 1 207,993,895 208,020,454 RGD:6480464
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:6480464
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Pecam1 platelet and endothelial cell adhesion molecule 1 JBrowse link 10 94,850,971 94,913,202 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 4 147,532,040 147,592,769 RGD:6480464
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Rps6 ribosomal protein S6 JBrowse link 5 105,197,821 105,200,681 RGD:6480464
G Rps6ka1 ribosomal protein S6 kinase A1 JBrowse link 5 152,078,217 152,122,684 RGD:6480464
G Shc1 SHC adaptor protein 1 JBrowse link 2 188,745,503 188,757,066 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        biochemical role 19178
          enzyme inhibitor 18079
            EC 1.* (oxidoreductase) inhibitor 16466
              EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor 14187
                EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor 1032
                  EC 1.14.14.14 (aromatase) inhibitor 327
                    7-hydroxyisoflavone + 104
                    TAN-931 0
                    alpha-naphthoflavone 137
                    aminoglutethimide + 53
                    anastrozole + 8
                    androsta-1,4,6-triene-3,17-dione 0
                    beta-(4-hydroxyphenyl)ethyl-4-O-E-caffeoyl-O-[beta-D-apiofuranosyl-(1->2)]-beta-D-glucopyranoside 0
                    exemestane 31
                    formestane 6
                    inflexin 0
                    letrozole 45
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.