Apool (apolipoprotein O-like) - Rat Genome Database

Gene: Apool (apolipoprotein O-like) Rattus norvegicus

Analyze

Symbol:

Apool

Name:

apolipoprotein O-like

RGD ID:

1549725

Description:

Predicted to be involved in cristae formation. Predicted to be located in mitochondrion. Predicted to be part of MICOS complex. Orthologous to human APOOL (apolipoprotein O like); PARTICIPATES IN mitochondrial protein import pathway; INTERACTS WITH (+)-schisandrin B; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC317191; MICOS complex subunit MIC27; RGD1549725; similar to RIKEN cDNA 9430083G14

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	APOOL (apolipoprotein O like)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Apool (apolipoprotein O-like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Apool (apolipoprotein O like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	APOOL (apolipoprotein O like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	APOOL (apolipoprotein O like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Apool (apolipoprotein O like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	APOOL (apolipoprotein O like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	APOOL (apolipoprotein O like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Apool (apolipoprotein O like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	APOOL (apolipoprotein O like)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Apool (apolipoprotein O-like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	apool (apolipoprotein O-like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG5903	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	moma-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	apool	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	81,569,960 - 81,635,906 (+)	NCBI		GRCr8
mRatBN7.2	X	77,377,723 - 77,443,672 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	77,377,781 - 77,443,900 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	79,035,091 - 79,101,043 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	82,466,054 - 82,531,979 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	80,054,183 - 80,120,122 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	83,678,269 - 83,750,550 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	83,678,339 - 83,750,549 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	83,639,368 - 83,708,627 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	100,911,059 - 100,979,133 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	78,677,758 - 78,743,289 (+)	NCBI		Celera
Cytogenetic Map	X	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

genetic disease (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (EXP)

6-propyl-2-thiouracil (EXP)

aconitine (EXP)

aflatoxin B1 (ISO)

amiodarone (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzbromarone (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bortezomib (ISO)

buspirone (EXP)

caffeine (ISO)

cisplatin (ISO)

clofibrate (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dicrotophos (ISO)

doxorubicin (ISO)

finasteride (EXP)

formaldehyde (ISO)

glycidyl methacrylate (ISO)

inulin (ISO)

isotretinoin (ISO)

L-ethionine (EXP)

methidathion (ISO)

methylmercury chloride (ISO)

omeprazole (EXP)

oxaliplatin (EXP)

paracetamol (EXP,ISO)

PCB138 (EXP)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (EXP)

temozolomide (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

tolcapone (EXP)

topotecan (EXP)

triptonide (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

cristae formation (IBA)

Cellular Component

MICOS complex (IBA,ISO)

mitochondrion (ISO)

Molecular Function

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

mitochondrial protein import pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
3.	Comprehensive gene review and curation	RGD comprehensive gene curation
4.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
5.	Mitofilin complexes: conserved organizers of mitochondrial membrane architecture.	Zerbes RM, etal., Biol Chem. 2012 Nov;393(11):1247-61. doi: 10.1515/hsz-2012-0239.

Additional References at PubMed

PMID:12865426	PMID:14651853	PMID:18614015	PMID:25781180	PMID:25997101

Genomics

Comparative Map Data

Apool
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	81,569,960 - 81,635,906 (+)	NCBI		GRCr8
mRatBN7.2	X	77,377,723 - 77,443,672 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	77,377,781 - 77,443,900 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	79,035,091 - 79,101,043 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	82,466,054 - 82,531,979 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	80,054,183 - 80,120,122 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	83,678,269 - 83,750,550 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	83,678,339 - 83,750,549 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	83,639,368 - 83,708,627 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	100,911,059 - 100,979,133 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	78,677,758 - 78,743,289 (+)	NCBI		Celera
Cytogenetic Map	X	q31	NCBI

APOOL
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	85,003,877 - 85,093,315 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	85,003,877 - 85,093,315 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	84,258,883 - 84,348,321 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	84,145,561 - 84,231,643 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	84,065,049 - 84,148,918	NCBI
Celera	X	84,498,355 - 84,587,725 (+)	NCBI		Celera
Cytogenetic Map	X	q21.1	NCBI
HuRef	X	77,832,958 - 77,921,872 (+)	NCBI		HuRef
CHM1_1	X	84,152,919 - 84,242,042 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	83,432,345 - 83,522,274 (+)	NCBI		T2T-CHM13v2.0

Apool
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	111,221,049 - 111,282,452 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	111,221,031 - 111,282,452 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	112,311,352 - 112,372,755 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	112,311,334 - 112,372,755 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	109,425,017 - 109,486,039 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	108,428,352 - 108,489,374 (+)	NCBI		MGSCv36	mm8
Celera	X	98,952,746 - 99,013,937 (+)	NCBI		Celera
Cytogenetic Map	X	E1	NCBI
cM Map	X	48.76	NCBI

Apool
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955529	3,849,256 - 3,929,648 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955529	3,849,326 - 3,929,588 (+)	NCBI	ChiLan1.0	ChiLan1.0

APOOL
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	84,482,909 - 84,572,125 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	84,486,526 - 84,575,732 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	74,075,468 - 74,159,315 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	84,186,044 - 84,270,217 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	84,186,060 - 84,334,662 (+)	Ensembl	panpan1.1		panPan2

APOOL
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	65,850,365 - 65,953,013 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	65,850,440 - 65,952,649 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	56,606,833 - 56,709,451 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	67,179,177 - 67,281,976 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	67,179,120 - 67,281,974 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	64,828,761 - 64,931,623 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	66,461,262 - 66,564,007 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	66,057,721 - 66,160,379 (+)	NCBI		UU_Cfam_GSD_1.0

Apool
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	59,469,822 - 59,537,982 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936547	5,790,283 - 5,860,198 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936547	5,790,287 - 5,858,054 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

APOOL
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	68,281,869 - 68,355,006 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	68,281,781 - 68,355,009 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	78,031,543 - 78,104,742 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

APOOL
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	73,844,065 - 73,925,754 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666067	6,912,002 - 7,002,594 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Apool
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624852	3,458,028 - 3,520,853 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624852	3,457,776 - 3,577,857 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Apool
140 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	95
Count of miRNA genes:	71
Interacting mature miRNAs:	83
Transcripts:	ENSRNOT00000005997
Prediction methods:	Miranda, Pita, Pita,Targetscan, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61430	Cia18	Collagen induced arthritis QTL 18	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	14843113	120568734	Rat
1598837	Memor13	Memory QTL 13	3.2		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	41052407	146860749	Rat
738035	Stresp1	Stress response QTL 1	4.96	0.000011	stress-related behavior trait (VT:0010451)	defensive burying - coping	X	41304447	112935181	Rat
61431	Cia19	Collagen induced arthritis QTL 19	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	65612192	120568734	Rat
724551	Glom1	Glomerulus QTL 1	2.8	0.0004	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	X	75294106	120294106	Rat

Markers in Region

RH139753

Rat Assembly	Chr	Position (strand)	Source	JBrowse
RH 3.4 Map	15	22.9	UniSTS
Cytogenetic Map	X	q31	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	17	41	8	10	42	35	34	11	8
Low					2			1	32		7
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001014105	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001393716	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC086434	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473969	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ219134	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228809	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ235331	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000005997 ⟹ ENSRNOP00000005997

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	77,377,781 - 77,443,900 (+)	Ensembl
Rnor_6.0 Ensembl	X	83,678,339 - 83,750,549 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000103551 ⟹ ENSRNOP00000095644

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	77,377,820 - 77,443,664 (+)	Ensembl

RefSeq Acc Id:

NM_001014105 ⟹ NP_001014127

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	81,570,035 - 81,635,906 (+)	NCBI
mRatBN7.2	X	77,377,798 - 77,443,672 (+)	NCBI
Rnor_6.0	X	83,678,339 - 83,750,550 (+)	NCBI
Rnor_5.0	X	83,639,368 - 83,708,627 (+)	NCBI
RGSC_v3.4	X	100,911,059 - 100,979,133 (+)	RGD
Celera	X	78,677,758 - 78,743,289 (+)	RGD

Sequence:

show sequence

CGAGAGGGTCATAGGTATGGCGGCCTTTAGGGTAAGTGAAAAGAAACTTAGTTTTCCACTGCCG
GCTCGCTTGAGCCCACAGCATTACAGTAATTGTAGAAGGGATCGTCTATCGTAACTCATGAAGG
GAGCCCCTCAGCAAGTGGCGGCCTGGAGATGAGAAAGTTGACAACCATGCCTGCAGGTCTGATA
TATGCATCTATAAATGTGCATCTGGCCAAAGAAGAGGAACCCAAAAAGCAGCTAGTGAGACCAG
AACAGCTCCCCATATATACTGCACCACCTCTCCATTCTAAATATGTTGAAGAACAGCCTGGTTA
TTTACAAAGGGGATTTACTTCCATCCGTACTACAACTGCTTATTATATTGGCTGGTGCAAGGGC
ATTTATCTCTTTATGAAAAATGGGGTCATGGATACAGTACAAATTGGAAAAGATGCATATGTCT
ATCTGAAGAATCCTCCTCAAGATTTTCTTCCCAAAATGGGAGTGATTACAGCTTCAGGATTGGC
AGGTTTGCTTTCAGCAAGAAAAGGTTCTAGGTTTAAGAAGATTGCTTATCCACTGGGACTGGCC
ACATTAGGAGCAACTGTTTGCTACCCTGCTCAGTCAGTAATAATTGCAAAGATAACTGGGAAAA
AGGCATACGCTACAAGCCATCAAATTTTTCAAGCCATTAAGTCAATGTGGACACAAAGCAGTGA
AAAAGAATTACTCCCTGAACCAAAGGAAGAAACCAAGGAAGGAAGGCCTGATGAAATCCATGCC
AAAACGCCTGACCTGGAACATTCGGTGTTTTTGCTAAAAGAACTTGCCTCTGCAACAAAGATTA
AATCAGAATCCACCTCAGGTACTACACAGTTTATACCTGACCCCAAGCTCATGGACCATGGGCA
GTCTCATCCAGATGATAAAGATATGTACAGCACTAGAAGCTGAACTTGAAGCTACATAGAGAAC
TGCAAGATGTACTACGTTGCAAACAATGATGAAAAAAAAATCACATAATGAACGGGTAACTGAC
AGAATGTGACTTGAAATTTTTCCATGACATTTTCAAATAAACAGTTTGGTCAATGAGACAAATG
GTAAAAACATAAATTAATGAATACAACACAAATAATATTAACTGATTGATGAGGGAACTGAAGT
AGTAGAAATACTAGGAGTATATTCTATGACTTGTAATAGAATTTATTAGAAAGCAAAATGAAGT
GAAGATATAAATGTCAGTAAGACTGAATTCTAAAAACATGCATATAAAAATATATGTATGTATA
TATGTATGTATTTATGTATCTGCTTCAGTTTTCCCAATTATTGCCAGTTAACTTAGAATGGGGT
CTAGAACAATATGTTTTTCACTTGACTTTTTTTTAGTGCTGGAATAAAATATCCATATTTTATG
GCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001393716 ⟹ NP_001380645

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	81,569,960 - 81,635,906 (+)	NCBI
mRatBN7.2	X	77,377,723 - 77,443,672 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001014127	(Get FASTA)	NCBI Sequence Viewer
	NP_001380645	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH86434	(Get FASTA)	NCBI Sequence Viewer
	EDM07083	(Get FASTA)	NCBI Sequence Viewer
	EDM07084	(Get FASTA)	NCBI Sequence Viewer
	EDM07085	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000005997
	ENSRNOP00000005997.6
	ENSRNOP00000095644.1

RefSeq Acc Id:	NP_001014127 ⟸ NM_001014105
- Peptide Label:	isoform 2
- UniProtKB:	F1M7F3 (UniProtKB/TrEMBL), Q5U1W6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPAGLIYASINVHLAKEEEPKKQLVRPEQLPIYTAPPLHSKYVEEQPGYLQRGFTSIRTTTAYY IGWCKGIYLFMKNGVMDTVQIGKDAYVYLKNPPQDFLPKMGVITASGLAGLLSARKGSRFKKIA YPLGLATLGATVCYPAQSVIIAKITGKKAYATSHQIFQAIKSMWTQSSEKELLPEPKEETKEGR PDEIHAKTPDLEHSVFLLKELASATKIKSESTSGTTQFIPDPKLMDHGQSHPDDKDMYSTRS hide sequence

RefSeq Acc Id:

ENSRNOP00000005997 ⟸ ENSRNOT00000005997

RefSeq Acc Id:

ENSRNOP00000095644 ⟸ ENSRNOT00000103551

RefSeq Acc Id:	NP_001380645 ⟸ NM_001393716
- Peptide Label:	isoform 1
- UniProtKB:	A0A8J8YNE4 (UniProtKB/TrEMBL), A6IV95 (UniProtKB/TrEMBL), F1M7F3 (UniProtKB/TrEMBL), Q5U1W6 (UniProtKB/TrEMBL)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5U1W6-F1-model_v2	AlphaFold	Q5U1W6	1-254	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701914

Promoter ID:

EPDNEW_R12438

Type:

initiation region

Name:

Apool_1

Description:

apolipoprotein O-like

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	X	83,678,291 - 83,678,351	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1549725	AgrOrtholog
BioCyc Gene	G2FUF-1835	BioCyc
Ensembl Genes	ENSRNOG00000004512	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000005997	ENTREZGENE
	ENSRNOT00000005997.8	UniProtKB/TrEMBL
	ENSRNOT00000103551.1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7302620	IMAGE-MGC_LOAD
InterPro	Apolipoprotein_O	UniProtKB/TrEMBL
	MIC26/MIC27_animal	UniProtKB/TrEMBL
KEGG Report	rno:317191	UniProtKB/TrEMBL
MGC_CLONE	MGC:105970	IMAGE-MGC_LOAD
NCBI Gene	317191	ENTREZGENE
PANTHER	MICOS COMPLEX SUBUNIT MIC27	UniProtKB/TrEMBL
	PTHR14564	UniProtKB/TrEMBL
Pfam	ApoO	UniProtKB/TrEMBL
PhenoGen	Apool	PhenoGen
RatGTEx	ENSRNOG00000004512	RatGTEx
UniProt	A0A8I6ANR0_RAT	UniProtKB/TrEMBL
	A0A8J8YNE4	ENTREZGENE, UniProtKB/TrEMBL
	A6IV95	ENTREZGENE, UniProtKB/TrEMBL
	F1M7F3	ENTREZGENE
	Q5U1W6	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	F1M7F3	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-07	Apool	apolipoprotein O-like	RGD1549725	similar to RIKEN cDNA 9430083G14	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	RGD1549725	similar to RIKEN cDNA 9430083G14	LOC317191		Symbol updated	1299863	APPROVED
2005-09-15	LOC317191	similar to RIKEN cDNA 9430083G14			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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