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Gene: C7 (complement C7) Rattus norvegicus
Symbol: C7
Name: complement C7
Description: Involved in cellular sodium ion homeostasis. Predicted to localize to the membrane attack complex. Used to study visual epilepsy. Biomarker of membranous glomerulonephritis and myocardial infarction. Human ortholog(s) of this gene implicated in complement component 7 deficiency. Orthologous to human C7 (complement C7); PARTICIPATES IN coagulation cascade pathway; complement system pathway; prion disease pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 1-nitropropane; 2,4-diaminotoluene.
Type: protein-coding
RefSeq Status: MODEL
Also known as: complement component 7; complement component C7; LOC310126
Homo sapiens (human) : C7 (complement C7)  HGNC  Alliance
Mus musculus (house mouse) : C7 (complement component 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : C7 (complement C7)
Pan paniscus (bonobo/pygmy chimpanzee) : C7 (complement C7)
Canis lupus familiaris (dog) : C7 (complement C7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : C7 (complement C7)
Sus scrofa (pig) : C7 (complement C7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0254,707,621 - 54,781,624 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl254,709,138 - 54,777,729 (-)Ensembl
Rnor_5.0273,735,309 - 73,806,693 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4254,147,136 - 54,250,803 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1254,080,702 - 54,129,568 (-)NCBI
Celera249,739,049 - 49,813,376 (-)NCBICelera
Cytogenetic Map2q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on C7
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620318
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.