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Gene: Gata4 (GATA binding protein 4) Rattus norvegicus
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Symbol: Gata4
Name: GATA binding protein 4
Description: Exhibits several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; enhancer sequence-specific DNA binding activity; and transcription factor binding activity. Involved in several processes, including cell growth involved in cardiac muscle cell development; regulation of transcription by RNA polymerase II; and transdifferentiation. Localizes to the nucleus. Used to study myocardial infarction. Biomarker of congenital heart disease and pulmonary hypertension. Human ortholog(s) of this gene implicated in congenital heart disease (multiple). Orthologous to human GATA4 (GATA binding protein 4); INTERACTS WITH 17alpha-ethynylestradiol; 1D-myo-inositol 1,4,5-trisphosphate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DNA-binding protein GATA-GT2; GATA-binding factor 4; GATA-binding protein 4; transcription factor GATA-4
Orthologs:
Homo sapiens (human) : GATA4 (GATA binding protein 4)  HGNC  Alliance
Mus musculus (house mouse) : Gata4 (GATA binding protein 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gata4 (GATA binding protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : GATA4 (GATA binding protein 4)
Canis lupus familiaris (dog) : GATA4 (GATA binding protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gata4 (GATA binding protein 4)
Sus scrofa (pig) : GATA4 (GATA binding protein 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01546,386,703 - 46,458,679 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01550,151,497 - 50,197,708 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41542,472,793 - 42,519,569 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11542,488,492 - 42,535,269 (-)NCBI
Celera1537,143,928 - 37,189,874 (-)NCBICelera
Cytogenetic Map15p12NCBI
RH 3.4 Map15261.71RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gata4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2665
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.