Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner
Aging & Age-Related Disease Cancer Cardiovascular Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Genetic Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Adh4 (alcohol dehydrogenase 4 (class II), pi polypeptide) Rattus norvegicus
Analyze
Symbol: Adh4
Name: alcohol dehydrogenase 4 (class II), pi polypeptide
Description: Exhibits NAD binding activity; alcohol dehydrogenase (NAD) activity; and ethanol binding activity. Involved in aging; ethanol oxidation; and ovulation cycle. Predicted to localize to the cytosol and nucleus. Orthologous to human ADH4 (alcohol dehydrogenase 4 (class II), pi polypeptide); PARTICIPATES IN fatty acid metabolic pathway; gluconeogenesis pathway; glycolysis pathway; INTERACTS WITH 1H-pyrazole; 2,3,7,8-tetrachlorodibenzodioxine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Ac1002; ADH-1; ADH2; alcohol dehydrogenase 4; alcohol dehydrogenase 4-like; alcohol dehydrogenase class II; alcohol dehydrogenase II; class II alcohol dehydrogenase, pi subunit
Orthologs:
Homo sapiens (human) : ADH4 (alcohol dehydrogenase 4 (class II), pi polypeptide)  HGNC  Alliance
Mus musculus (house mouse) : Adh4 (alcohol dehydrogenase 4 (class II), pi polypeptide)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : ADH4 (alcohol dehydrogenase 4 (class II), pi polypeptide)
Canis lupus familiaris (dog) : ADH4 (alcohol dehydrogenase 4 (class II), pi polypeptide)
Sus scrofa (pig) : ADH4 (alcohol dehydrogenase 4 (class II), pi polypeptide)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02243,702,035 - 243,720,063 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02262,237,059 - 262,254,499 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42235,952,313 - 235,970,671 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12235,939,028 - 235,957,343 (+)NCBI
Celera2219,105,553 - 219,122,791 (+)NCBICelera
Cytogenetic Map2q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Adh4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 71028
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



Contact Us |  About Us |  License CC BY 4.0 |  Legal Disclaimer |  © Medical College of Wisconsin
NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.