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Gene: Ears2 (glutamyl-tRNA synthetase 2, mitochondrial) Rattus norvegicus
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Symbol: Ears2
Name: glutamyl-tRNA synthetase 2, mitochondrial
Description: Predicted to have glutamate-tRNA ligase activity and glutamate-tRNA(Gln) ligase activity. Predicted to be involved in glutamyl-tRNA aminoacylation and tRNA aminoacylation for mitochondrial protein translation. Predicted to localize to the mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency. Orthologous to human EARS2 (glutamyl-tRNA synthetase 2, mitochondrial); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; glutamic acid/glutamate metabolic pathway; homocarnosinosis pathway; INTERACTS WITH 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil; amiodarone.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: glutamyl-tRNA synthetase 2 mitochondrial (putative); LOC361641; probable glutamate--tRNA ligase, mitochondrial; probable glutamyl-tRNA synthetase, mitochondrial; RGD1307904; similar to RIKEN cDNA 3230401I01
Orthologs:
Homo sapiens (human) : EARS2 (glutamyl-tRNA synthetase 2, mitochondrial)  HGNC  Alliance
Mus musculus (house mouse) : Ears2 (glutamyl-tRNA synthetase 2, mitochondrial)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ears2 (glutamyl-tRNA synthetase 2, mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : EARS2 (glutamyl-tRNA synthetase 2, mitochondrial)
Canis lupus familiaris (dog) : EARS2 (glutamyl-tRNA synthetase 2, mitochondrial)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ears2 (glutamyl-tRNA synthetase 2, mitochondrial)
Sus scrofa (pig) : EARS2 (glutamyl-tRNA synthetase 2, mitochondrial)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01191,997,512 - 192,025,350 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01199,083,532 - 199,087,792 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01198,699,309 - 198,716,446 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41180,861,635 - 180,889,473 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11181,001,656 - 181,029,365 (-)NCBI
Celera1174,307,704 - 174,335,598 (-)NCBICelera
Cytogenetic Map1q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Alliance Gene
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JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 1307904
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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