Gene: Kcnk18 (potassium two pore domain channel subfamily K member 18) Rattus norvegicus
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Symbol: Kcnk18
Name: potassium two pore domain channel subfamily K member 18
Description: ENCODES a protein that exhibits calcium-activated potassium channel activity (ortholog); outward rectifier potassium channel activity (ortholog); INVOLVED IN cellular response to pH (ortholog); potassium ion export across plasma membrane (ortholog); potassium ion transport (ortholog); ASSOCIATED WITH migraine (ortholog); migraine with aura (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH bisphenol A; vinclozolin; 2,3,7,8-tetrachlorodibenzodioxine (ortholog)
AGR Description: Predicted to have calcium-activated potassium channel activity, outward rectifier potassium channel activity, and potassium ion leak channel activity; predicted to be involved in cellular response to pH, potassium ion export across plasma membrane, and stabilization of membrane potential; predicted to localize to the integral component of plasma membrane; orthologous to human KCNK18 (potassium two pore domain channel subfamily K member 18).
Merged Description: Predicted to have calcium-activated potassium channel activity, outward rectifier potassium channel activity, and potassium ion leak channel activity; predicted to be involved in cellular response to pH, potassium ion export across plasma membrane, and stabilization of membrane potential; predicted to localize to the integral component of plasma membrane; orthologous to human KCNK18 (potassium two pore domain channel subfamily K member 18); INTERACTS WITH bisphenol A; vinclozolin; 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: potassium channel subfamily K member 18; potassium channel, subfamily K, member 18; potassium channel, two pore domain subfamily K, member 18; tandem-pore K+ (K(2P)) channel; Tresk-2; two-pore-domain potassium channel TRESK
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01280,383,579 - 280,397,784 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01287,744,272 - 287,758,268 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41265,749,192 - 265,764,641 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11265,960,270 - 265,975,609 (+)NCBI
Celera1254,028,695 - 254,042,550 (+)NCBICelera
Cytogenetic Map1q55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Kcnk18
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1303091
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.