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Gene: Bckdk (branched chain ketoacid dehydrogenase kinase) Rattus norvegicus
Symbol: Bckdk
Name: branched chain ketoacid dehydrogenase kinase
Description: Exhibits ATP binding activity; [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity; and protein serine/threonine kinase activity. Involved in branched-chain amino acid catabolic process and phosphorylation. Localizes to mitochondrial alpha-ketoglutarate dehydrogenase complex. Human ortholog(s) of this gene implicated in branched-chain keto acid dehydrogenase kinase deficiency. Orthologous to human BCKDK (branched chain keto acid dehydrogenase kinase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; clofibric acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; BCKD-kinase; BCKDHKIN; branched chain keto acid dehydrogenase kinase; branched-chain alpha-ketoacid dehydrogenase kinase
Homo sapiens (human) : BCKDK (branched chain keto acid dehydrogenase kinase)  HGNC  Alliance
Mus musculus (house mouse) : Bckdk (branched chain ketoacid dehydrogenase kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bckdk (branched chain keto acid dehydrogenase kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : BCKDK (branched chain keto acid dehydrogenase kinase)
Canis lupus familiaris (dog) : BCKDK (branched chain keto acid dehydrogenase kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bckdk (branched chain keto acid dehydrogenase kinase)
Sus scrofa (pig) : BCKDK (branched chain keto acid dehydrogenase kinase)
Chlorocebus sabaeus (African green monkey) : BCKDK (branched chain keto acid dehydrogenase kinase)
Heterocephalus glaber (naked mole-rat) : Bckdk (branched chain keto acid dehydrogenase kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01199,351,628 - 199,356,299 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1199,351,628 - 199,356,881 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01206,374,221 - 206,378,892 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41187,189,665 - 187,194,336 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11187,340,263 - 187,344,799 (+)NCBI
Celera1180,166,156 - 180,170,827 (+)NCBICelera
Cytogenetic Map1q37NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Bckdk
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2198
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.