Myl6 (myosin light chain 6) - Rat Genome Database
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Gene: Myl6 (myosin light chain 6) Rattus norvegicus
Analyze
Symbol: Myl6
Name: myosin light chain 6
RGD ID: 1589019
Description: Predicted to have actin-dependent ATPase activity. Predicted to be a structural constituent of muscle. Predicted to localize to brush border and unconventional myosin complex. Orthologous to human MYL6 (myosin light chain 6); INTERACTS WITH 17alpha-ethynylestradiol; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC685867; MGC188345; myosin light polypeptide 6; myosin, light chain 6, alkali, smooth muscle and non-muscle; similar to myosin, light polypeptide 6, alkali, smooth muscle and non-muscle
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27910,764 - 914,062 (-)NCBI
Rnor_6.0 Ensembl72,906,137 - 2,909,179 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.072,906,137 - 2,909,193 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.072,880,878 - 2,882,625 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,772,621 - 1,775,663 (-)NCBIRGSC3.4rn4RGSC3.4
Celera7783,878 - 786,920 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
1. RGD automated data pipeline
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2304459   PMID:12477932   PMID:15632090   PMID:16953301   PMID:19190083   PMID:19946888   PMID:20458337   PMID:21700703   PMID:22114352   PMID:23376485   PMID:23533145   PMID:23979707  
PMID:24625528  


Genomics

Comparative Map Data
Myl6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27910,764 - 914,062 (-)NCBI
Rnor_6.0 Ensembl72,906,137 - 2,909,179 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.072,906,137 - 2,909,193 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.072,880,878 - 2,882,625 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,772,621 - 1,775,663 (-)NCBIRGSC3.4rn4RGSC3.4
Celera7783,878 - 786,920 (-)NCBICelera
Cytogenetic Map7q11NCBI
MYL6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1256,158,346 - 56,163,496 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1256,158,161 - 56,163,496 (+)EnsemblGRCh38hg38GRCh38
GRCh381256,158,359 - 56,161,579 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371256,552,143 - 56,555,363 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361254,838,367 - 54,841,633 (+)NCBINCBI36hg18NCBI36
Build 341254,838,412 - 54,841,625NCBI
Celera1256,204,244 - 56,207,510 (+)NCBI
Cytogenetic Map12q13.2NCBI
HuRef1253,591,104 - 53,594,425 (+)NCBIHuRef
CHM1_11256,519,428 - 56,522,749 (+)NCBICHM1_1
Myl6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,326,728 - 128,329,755 (-)NCBIGRCm39mm39
GRCm39 Ensembl10128,326,729 - 128,330,014 (-)Ensembl
GRCm3810128,490,859 - 128,493,886 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,490,860 - 128,494,145 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710127,927,917 - 127,930,881 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610127,893,810 - 127,896,774 (-)NCBImm8
Celera10130,882,814 - 130,885,778 (-)NCBICelera
Cytogenetic Map10D3NCBI
Myl6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554583,760,695 - 3,763,652 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554583,760,695 - 3,763,652 (+)NCBIChiLan1.0ChiLan1.0
MYL6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11233,004,923 - 33,008,329 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1233,004,181 - 33,008,329 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01232,754,146 - 32,757,436 (-)NCBIMhudiblu_PPA_v0panPan3
MYL6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl10476,989 - 480,827 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.110476,944 - 480,122 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Myl6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936646567,112 - 570,348 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYL6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl521,486,312 - 21,563,425 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1521,559,226 - 21,562,418 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2523,251,782 - 23,254,969 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MYL6
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11152,099,075 - 52,102,205 (+)NCBI
Myl6
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462480211,847,061 - 11,850,187 (-)NCBI

Position Markers
RH132927  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.072,909,489 - 2,909,668NCBIRnor6.0
Rnor_5.072,882,914 - 2,883,093UniSTSRnor5.0
RGSC_v3.471,775,973 - 1,776,152UniSTSRGSC3.4
Celera7787,230 - 787,409UniSTS
Cytogenetic Map7q11UniSTS
MARC_5817-5818:991939742:3  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01233,182,625 - 33,182,924NCBIRnor6.0
Rnor_5.01235,081,483 - 35,081,782UniSTSRnor5.0
Rnor_5.072,881,097 - 2,881,396UniSTSRnor5.0
RGSC_v3.41230,532,503 - 30,532,802UniSTSRGSC3.4
Celera1231,175,080 - 31,175,379UniSTS
Cytogenetic Map7q11UniSTS
Cytogenetic Map12q14UniSTS
Myln  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.072,906,296 - 2,907,635NCBIRnor6.0
RGSC_v3.471,772,780 - 1,774,119UniSTSRGSC3.4
Celera7784,037 - 785,376UniSTS
Cytogenetic Map7q11UniSTS
Cytogenetic Map13p11UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7134147172Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7134828535Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7134828535Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7137009673Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7138119654Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)7265313832258115Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:58
Count of miRNA genes:45
Interacting mature miRNAs:51
Transcripts:ENSRNOT00000071616
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 1 2 2
Medium 2 41 57 41 19 41 8 11 74 35 41 9 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001109484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC128207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC166586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: NM_001109484   ⟹   NP_001102954
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27910,764 - 913,806 (-)NCBI
Rnor_6.072,906,137 - 2,909,179 (-)NCBI
Rnor_5.072,880,878 - 2,882,625 (-)NCBI
RGSC_v3.471,772,621 - 1,775,663 (-)RGD
Celera7783,878 - 786,920 (-)RGD
Sequence:
RefSeq Acc Id: XM_008765039   ⟹   XP_008763261
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27910,772 - 914,062 (-)NCBI
Rnor_6.072,906,148 - 2,909,193 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765040   ⟹   XP_008763262
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27910,772 - 914,062 (-)NCBI
Rnor_6.072,906,145 - 2,909,193 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017595113   ⟹   XP_017450602
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27910,772 - 914,062 (-)NCBI
Rnor_6.072,906,145 - 2,909,153 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017595114   ⟹   XP_017450603
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27910,772 - 914,062 (-)NCBI
Rnor_6.072,906,145 - 2,909,153 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079906   ⟹   XP_038935834
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27910,956 - 914,062 (-)NCBI
RefSeq Acc Id: XM_039079907   ⟹   XP_038935835
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27910,772 - 912,959 (-)NCBI
RefSeq Acc Id: XM_039079908   ⟹   XP_038935836
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27910,772 - 912,966 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001102954   ⟸   NM_001109484
- UniProtKB: A0A0G2K6J5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763262   ⟸   XM_008765040
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008763261   ⟸   XM_008765039
- Peptide Label: isoform X1
- UniProtKB: B2GV99 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450602   ⟸   XM_017595113
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017450603   ⟸   XM_017595114
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_038935836   ⟸   XM_039079908
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038935835   ⟸   XM_039079907
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038935834   ⟸   XM_039079906
- Peptide Label: isoform X3
Protein Domains
EF-hand

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694952
Promoter ID:EPDNEW_R5464
Type:initiation region
Name:Myl6_1
Description:myosin light chain 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.072,909,148 - 2,909,208EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1589019 AgrOrtholog
Ensembl Genes ENSRNOG00000054140 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000070200 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000073838 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000082518 UniProtKB/TrEMBL
  ENSRNOT00000089074 ENTREZGENE, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7934414 IMAGE-MGC_LOAD
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
KEGG Report rno:685867 UniProtKB/TrEMBL
MGC_CLONE MGC:188345 IMAGE-MGC_LOAD
NCBI Gene 685867 ENTREZGENE
PhenoGen Myl6 PhenoGen
PROSITE EF_HAND_2 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A0G2K6J5 ENTREZGENE, UniProtKB/TrEMBL
  B2GV99 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-10 Myl6  myosin light chain 6  Myl6  myosin, light chain 6, alkali, smooth muscle and non-muscle  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Myl6  myosin, light chain 6, alkali, smooth muscle and non-muscle  LOC685867  similar to myosin, light polypeptide 6, alkali, smooth muscle and non-muscle  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC685867  similar to myosin, light polypeptide 6, alkali, smooth muscle and non-muscle      Symbol and Name status set to provisional 70820 PROVISIONAL