17alpha-ethynylestradiol multiple interactions ISO RGD:1551755 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LRG1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression ISO RGD:1551755 6480464 Ethinyl Estradiol results in increased expression of LRG1 mRNA CTD PMID:17942748 17beta-estradiol affects expression ISO RGD:1551755 6480464 Estradiol affects the expression of LRG1 mRNA CTD PMID:15598610 17beta-estradiol multiple interactions ISO RGD:1349039 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of LRG1 mRNA CTD PMID:30165855 17beta-estradiol increases expression ISO RGD:1551755 6480464 Estradiol results in increased expression of LRG1 mRNA CTD PMID:15289156 , PMID:19484750 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1551755 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LRG1 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1349039 6480464 Tetrachlorodibenzodioxin results in increased expression of LRG1 mRNA CTD PMID:21632981 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1551755 6480464 Tetrachlorodibenzodioxin results in decreased expression of LRG1 mRNA CTD PMID:19770486 2,4,6-trinitrobenzenesulfonic acid increases expression ISO RGD:1551755 6480464 Trinitrobenzenesulfonic Acid results in increased expression of LRG1 mRNA CTD PMID:17982090 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of LRG1 mRNA CTD PMID:24780913 aflatoxin B1 decreases expression ISO RGD:1551755 6480464 Aflatoxin B1 results in decreased expression of LRG1 mRNA CTD PMID:19770486 aflatoxin B1 decreases expression ISO RGD:1349039 6480464 Aflatoxin B1 results in decreased expression of LRG1 mRNA CTD PMID:27153756 all-trans-retinoic acid increases expression ISO RGD:1349039 6480464 Tretinoin results in increased expression of LRG1 mRNA CTD PMID:23830798 amphetamine increases expression EXP 6480464 Amphetamine results in increased expression of LRG1 mRNA CTD PMID:30779732 antirheumatic drug decreases expression ISO RGD:1349039 6480464 Antirheumatic Agents results in decreased expression of LRG1 mRNA CTD PMID:24449571 Aroclor 1254 increases expression ISO RGD:1551755 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of LRG1 mRNA CTD PMID:23650126 atrazine increases expression ISO RGD:1349039 6480464 Atrazine results in increased expression of LRG1 mRNA CTD PMID:22378314 benzo[a]pyrene decreases expression ISO RGD:1551755 6480464 Benzo(a)pyrene results in decreased expression of LRG1 mRNA CTD PMID:19770486 benzo[a]pyrene increases expression ISO RGD:1349039 6480464 Benzo(a)pyrene results in increased expression of LRG1 mRNA CTD PMID:20064835 more ... benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of LRG1 mRNA CTD PMID:21839799 bexarotene multiple interactions EXP 6480464 [bexarotene co-treated with Tamoxifen] results in decreased expression of LRG1 mRNA CTD PMID:17630414 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of LRG1 promoter CTD PMID:23359474 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of LRG1 promoter CTD PMID:23359474 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of LRG1 mRNA CTD PMID:25181051 cadmium atom affects binding ISO RGD:1349039 6480464 LRG1 protein binds to Cadmium CTD PMID:23896426 cadmium dichloride decreases expression ISO RGD:1349039 6480464 Cadmium Chloride results in decreased expression of LRG1 mRNA CTD PMID:26472689 carbon nanotube increases expression ISO RGD:1551755 6480464 Nanotubes, Carbon analog results in increased expression of LRG1 mRNA, Nanotubes, Carbon results in increased expression of LRG1 mRNA CTD PMID:25554681 more ... choline multiple interactions ISO RGD:1551755 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of LRG1 gene CTD PMID:20938992 cisplatin increases expression ISO RGD:1349039 6480464 Cisplatin results in increased expression of LRG1 mRNA CTD PMID:27594783 clofibrate decreases expression ISO RGD:1551755 6480464 Clofibrate results in decreased expression of LRG1 mRNA CTD PMID:17585979 copper atom affects binding ISO RGD:1349039 6480464 LRG1 protein binds to Copper CTD PMID:23896426 copper(0) affects binding ISO RGD:1349039 6480464 LRG1 protein binds to Copper CTD PMID:23896426 copper(II) sulfate decreases expression ISO RGD:1349039 6480464 Copper Sulfate results in decreased expression of LRG1 mRNA CTD PMID:19549813 crocidolite asbestos increases expression ISO RGD:1551755 6480464 Asbestos, Crocidolite results in increased expression of LRG1 mRNA CTD PMID:23917077 cyclosporin A decreases expression ISO RGD:1349039 6480464 Cyclosporine results in decreased expression of LRG1 mRNA CTD PMID:20106945 , PMID:25562108 daidzein multiple interactions ISO RGD:1349039 6480464 [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 daidzein 7-O-beta-D-glucoside multiple interactions ISO RGD:1349039 6480464 [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 dextran sulfate increases expression ISO RGD:1551755 6480464 Dextran Sulfate results in increased expression of LRG1 mRNA CTD PMID:23894361 dibutyl phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of LRG1 promoter CTD PMID:23359474 dichloroacetic acid decreases expression ISO RGD:1551755 6480464 Dichloroacetic Acid results in decreased expression of LRG1 mRNA CTD PMID:28962523 diclofenac increases expression ISO RGD:1551755 6480464 Diclofenac results in increased expression of LRG1 mRNA CTD PMID:26934552 diethylstilbestrol increases expression ISO RGD:1551755 6480464 Diethylstilbestrol results in increased expression of LRG1 mRNA CTD PMID:15289156 dioxygen multiple interactions ISO RGD:1551755 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of LRG1 mRNA CTD PMID:30529165 fluoxetine increases expression EXP 6480464 Fluoxetine results in increased expression of LRG1 mRNA CTD PMID:17033635 folic acid multiple interactions ISO RGD:1551755 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of LRG1 gene CTD PMID:20938992 genistein increases expression ISO RGD:1551755 6480464 Genistein results in increased expression of LRG1 mRNA CTD PMID:15289156 genistein multiple interactions ISO RGD:1349039 6480464 [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 genistein decreases expression ISO RGD:1551755 6480464 Genistein results in decreased expression of LRG1 mRNA CTD PMID:21048042 genistein 7-O-beta-D-glucoside multiple interactions ISO RGD:1349039 6480464 [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 glafenine increases expression EXP 6480464 Glafenine results in increased expression of LRG1 mRNA CTD PMID:24136188 glycitein multiple interactions ISO RGD:1349039 6480464 [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 glycitin multiple interactions ISO RGD:1349039 6480464 [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 isoprenaline increases expression ISO RGD:1551755 6480464 Isoproterenol results in increased expression of LRG1 mRNA CTD PMID:20003209 L-methionine multiple interactions ISO RGD:1551755 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of LRG1 gene CTD PMID:20938992 lipopolysaccharide increases expression ISO RGD:1551755 6480464 Lipopolysaccharides results in increased expression of LRG1 mRNA CTD PMID:25890327 , PMID:27339419 naphthalene increases expression ISO RGD:1551755 6480464 naphthalene results in increased expression of LRG1 mRNA CTD PMID:18978301 nevirapine increases expression EXP 6480464 Nevirapine metabolite results in increased expression of LRG1 mRNA CTD PMID:23947594 nickel atom increases expression ISO RGD:1551755 6480464 Nickel results in increased expression of LRG1 mRNA CTD PMID:12540486 nickel atom affects binding ISO RGD:1349039 6480464 LRG1 protein binds to Nickel CTD PMID:23896426 oxaliplatin increases expression EXP 6480464 oxaliplatin results in increased expression of LRG1 mRNA CTD PMID:25729387 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of LRG1 mRNA CTD PMID:25729387 ozone increases expression ISO RGD:1551755 6480464 Ozone results in increased expression of LRG1 mRNA CTD PMID:12763052 ozone multiple interactions ISO RGD:1551755 6480464 [NOTCH4 gene mutant form affects the susceptibility to Ozone] which results in decreased expression of LRG1 mRNA, TTPA protein affects the reaction [Ozone results in increased expression of LRG1 mRNA] CTD PMID:19555225 , PMID:25658374 paracetamol affects expression ISO RGD:1551755 6480464 Acetaminophen affects the expression of LRG1 mRNA CTD PMID:17562736 paracetamol decreases expression ISO RGD:1349039 6480464 Acetaminophen results in decreased expression of LRG1 mRNA CTD PMID:21420995 phenobarbital affects expression ISO RGD:1349039 6480464 Phenobarbital affects the expression of LRG1 mRNA CTD PMID:19159669 phenobarbital affects expression ISO RGD:1551755 6480464 Phenobarbital affects the expression of LRG1 mRNA CTD PMID:23091169 pirinixic acid increases expression ISO RGD:1551755 6480464 pirinixic acid results in increased expression of LRG1 mRNA CTD PMID:18445702 pirinixic acid decreases expression ISO RGD:1551755 6480464 pirinixic acid results in decreased expression of LRG1 mRNA CTD PMID:23811191 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:1551755 6480464 Pregnenolone Carbonitrile results in increased expression of LRG1 mRNA CTD PMID:28903501 propofol increases expression ISO RGD:1551755 6480464 Propofol results in increased expression of LRG1 mRNA CTD PMID:21786383 protein kinase inhibitor multiple interactions ISO RGD:1349039 6480464 Protein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of LRG1 mRNA] CTD PMID:28003376 quercetin decreases expression ISO RGD:1349039 6480464 Quercetin results in decreased expression of LRG1 mRNA CTD PMID:21632981 rotenone increases expression EXP 6480464 Rotenone results in increased expression of LRG1 mRNA CTD PMID:28374803 silicon dioxide decreases expression ISO RGD:1349039 6480464 Silicon Dioxide analog results in decreased expression of LRG1 mRNA CTD PMID:25895662 silicon dioxide increases expression ISO RGD:1551755 6480464 Silicon Dioxide results in increased expression of LRG1 mRNA CTD PMID:23221170 sodium arsenite affects expression ISO RGD:1551755 6480464 sodium arsenite affects the expression of LRG1 mRNA CTD PMID:17450228 sodium dichromate increases expression ISO RGD:1551755 6480464 sodium bichromate results in increased expression of LRG1 mRNA CTD PMID:27859739 sodium fluoride increases expression ISO RGD:1551755 6480464 Sodium Fluoride results in increased expression of LRG1 protein CTD PMID:28918527 Soman increases expression EXP 6480464 Soman results in increased expression of LRG1 mRNA CTD PMID:19281266 sulforaphane increases expression ISO RGD:1349039 6480464 sulforafan results in increased expression of LRG1 mRNA CTD PMID:26833863 tamoxifen multiple interactions EXP 6480464 [bexarotene co-treated with Tamoxifen] results in decreased expression of LRG1 mRNA CTD PMID:17630414 tetrachloromethane increases expression ISO RGD:1551755 6480464 Carbon Tetrachloride results in increased expression of LRG1 mRNA CTD PMID:27339419 tetrachloromethane multiple interactions ISO RGD:1551755 6480464 [PANX1 protein co-treated with Carbon Tetrachloride] affects the expression of LRG1 mRNA CTD PMID:29987408 titanium dioxide increases expression ISO RGD:1551755 6480464 titanium dioxide results in increased expression of LRG1 mRNA CTD PMID:23409001 , PMID:27760801 titanium dioxide affects expression ISO RGD:1551755 6480464 titanium dioxide affects the expression of LRG1 mRNA CTD PMID:23557971 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of LRG1 mRNA CTD PMID:25729387 triclosan increases expression ISO RGD:1349039 6480464 Triclosan results in increased expression of LRG1 mRNA CTD PMID:30510588 trimellitic anhydride decreases expression ISO RGD:1551755 6480464 trimellitic anhydride results in decreased expression of LRG1 mRNA CTD PMID:19042947 tungsten decreases expression ISO RGD:1551755 6480464 Tungsten results in decreased expression of LRG1 mRNA CTD PMID:30912803 valproic acid decreases expression ISO RGD:1349039 6480464 Valproic Acid results in decreased expression of LRG1 mRNA CTD PMID:29154799 XL147 multiple interactions ISO RGD:1551755 6480464 [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of LRG1 mRNA CTD PMID:27935865 zoledronic acid increases expression ISO RGD:1349039 6480464 zoledronic acid results in increased expression of LRG1 mRNA CTD PMID:24714768
Biological Process brown fat cell differentiation ISO RGD:1551755 1624291 (MGI:MGI:3801349, PMID:18492766) RGD MGI:MGI:3801349 , PMID:18492766 brown fat cell differentiation IEA UniProtKB:Q91XL1 , ensembl:ENSMUSP000000380481600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of angiogenesis ISO RGD:1551755 1624291 MGI:MGI:1338946 more ... RGD MGI:MGI:5543310 , PMID:23868260 positive regulation of angiogenesis IEA UniProtKB:Q91XL1 , ensembl:ENSMUSP000000380481600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of endothelial cell proliferation ISO RGD:1551755 1624291 (MGI:MGI:5543310, PMID:23868260) RGD MGI:MGI:5543310 , PMID:23868260 positive regulation of endothelial cell proliferation IEA UniProtKB:Q91XL1 , ensembl:ENSMUSP000000380481600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of transforming growth factor beta receptor signaling pathway ISO RGD:1551755 1624291 MGI:MGI:98725 (MGI:MGI:5543310 , PMID:23868260) RGD MGI:MGI:5543310 , PMID:23868260 positive regulation of transforming growth factor beta receptor signaling pathway IEA UniProtKB:Q91XL1 , ensembl:ENSMUSP000000380481600115 GO_REF:0000107 Ensembl GO_REF:0000107 response to bacterium IEA UniProtKB:Q91XL1 , ensembl:ENSMUSP000000380481600115 GO_REF:0000107 Ensembl GO_REF:0000107 response to bacterium ISO RGD:1551755 1624291 (MGI:MGI:5448596, PMID:23012479) RGD MGI:MGI:5448596 , PMID:23012479 Cellular Component extracellular space ISO RGD:1349039 1624291 (PMID:20363744) RGD PMID:20363744 extracellular space IEA UniProtKB:Q91XL1 , ensembl:ENSMUSP000000380481600115 GO_REF:0000107 Ensembl GO_REF:0000107 extracellular space IEA UniProtKB:P02750 , ensembl:ENSP000003026211600115 GO_REF:0000107 Ensembl GO_REF:0000107 extracellular space ISO RGD:1551755 1624291 (MGI:MGI:5543310, PMID:23868260) RGD MGI:MGI:5543310 , PMID:23868260 intracellular membrane-bounded organelle IEA UniProtKB:P02750 , ensembl:ENSP000003026211600115 GO_REF:0000107 Ensembl GO_REF:0000107 intracellular membrane-bounded organelle ISO RGD:1349039 1624291 RGD GO_REF:0000052 Molecular Function protein binding ISO RGD:1349039 1624291 UniProtKB:P17813-1 more ... RGD PMID:23868260 transforming growth factor beta receptor binding ISO RGD:1551755 1624291 UniProtKB:Q62312 more ... RGD MGI:MGI:5543310 , PMID:23868260 transforming growth factor beta receptor binding IEA UniProtKB:Q91XL1 , ensembl:ENSMUSP000000380481600115 GO_REF:0000107 Ensembl GO_REF:0000107
Gene-Chemical Interaction Annotations
