Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of PNMA2 mRNA | CTD | PMID:29097150 | 17beta-estradiol | multiple interactions | ISO | PNMA2 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of PNMA2 mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Pnma2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PNMA2 mRNA | CTD | PMID:19465110 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PNMA2 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | PNMA2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PNMA2 mRNA | CTD | PMID:26159488 | 2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one | increases expression | ISO | Pnma2 (Mus musculus) | 6480464 | Itraconazole results in increased expression of PNMA2 mRNA | CTD | PMID:31099283 | 5-aza-2'-deoxycytidine | affects expression | ISO | PNMA2 (Homo sapiens) | 6480464 | Decitabine affects the expression of PNMA2 mRNA | CTD | PMID:23300844 | 5-aza-2'-deoxycytidine | multiple interactions | ISO | PNMA2 (Homo sapiens) | 6480464 | Decitabine inhibits the reaction [Smoke results in decreased expression of PNMA2 mRNA] | CTD | PMID:21095227 | 5-fluorouracil | affects response to substance | ISO | PNMA2 (Homo sapiens) | 6480464 | PNMA2 protein affects the susceptibility to Fluorouracil | CTD | PMID:16217747 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of PNMA2 mRNA | CTD | PMID:24780913 | acrylamide | decreases expression | ISO | Pnma2 (Mus musculus) | 6480464 | Acrylamide results in decreased expression of PNMA2 mRNA | CTD | PMID:30807115 | aflatoxin B1 | decreases methylation | ISO | PNMA2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of PNMA2 gene | CTD | PMID:27153756 | all-trans-retinoic acid | decreases expression | ISO | PNMA2 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of PNMA2 mRNA | CTD | PMID:21934132 | belinostat | decreases expression | ISO | PNMA2 (Homo sapiens) | 6480464 | belinostat results in decreased expression of PNMA2 mRNA | CTD | PMID:26272509 | belinostat | multiple interactions | ISO | PNMA2 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PNMA2 mRNA | CTD | PMID:27188386 | benzo[a]pyrene | multiple interactions | ISO | Pnma2 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of PNMA2 mRNA | CTD | PMID:27858113 | benzo[a]pyrene | increases expression | ISO | PNMA2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of PNMA2 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | affects methylation | ISO | PNMA2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of PNMA2 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | Pnma2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of PNMA2 5' UTR more ... | CTD | PMID:27901495 | benzo[b]fluoranthene | multiple interactions | ISO | Pnma2 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of PNMA2 mRNA | CTD | PMID:27858113 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PNMA2 mRNA | CTD | PMID:25181051 and PMID:30816183 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PNMA2 mRNA | CTD | PMID:29097150 | butan-1-ol | multiple interactions | ISO | PNMA2 (Homo sapiens) | 6480464 | [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of PNMA2 mRNA | CTD | PMID:29432896 | carbon nanotube | decreases expression | ISO | Pnma2 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | PNMA2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PNMA2 gene] | CTD | PMID:28238834 | chrysene | multiple interactions | ISO | Pnma2 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of PNMA2 mRNA | CTD | PMID:27858113 | cisplatin | affects expression | ISO | PNMA2 (Homo sapiens) | 6480464 | Cisplatin affects the expression of PNMA2 mRNA | CTD | PMID:23300844 | copper atom | multiple interactions | ISO | PNMA2 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in increased expression of PNMA2 mRNA | CTD | PMID:24690739 | copper(0) | multiple interactions | ISO | PNMA2 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in increased expression of PNMA2 mRNA | CTD | PMID:24690739 | disulfiram | multiple interactions | ISO | PNMA2 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in increased expression of PNMA2 mRNA | CTD | PMID:24690739 | dorsomorphin | multiple interactions | ISO | PNMA2 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | PNMA2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of PNMA2 mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of PNMA2 mRNA | CTD | PMID:29391264 | folic acid | decreases expression | ISO | Pnma2 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of PNMA2 mRNA | CTD | PMID:25629700 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of PNMA2 mRNA | CTD | PMID:33387578 | itraconazole | increases expression | ISO | Pnma2 (Mus musculus) | 6480464 | Itraconazole results in increased expression of PNMA2 mRNA | CTD | PMID:31099283 | methotrexate | affects response to substance | ISO | PNMA2 (Homo sapiens) | 6480464 | PNMA2 protein affects the susceptibility to Methotrexate | CTD | PMID:16217747 | N-nitrosodiethylamine | increases expression | ISO | PNMA2 (Homo sapiens) | 6480464 | Diethylnitrosamine results in increased expression of PNMA2 mRNA | CTD | PMID:21527772 | O-methyleugenol | increases expression | ISO | PNMA2 (Homo sapiens) | 6480464 | methyleugenol results in increased expression of PNMA2 mRNA | CTD | PMID:32234424 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of PNMA2 mRNA | CTD | PMID:33387578 | PCB138 | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:23829299 | SB 431542 | multiple interactions | ISO | PNMA2 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenite | increases expression | ISO | PNMA2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of PNMA2 mRNA | CTD | PMID:29301061 | sunitinib | decreases expression | ISO | PNMA2 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of PNMA2 mRNA | CTD | PMID:31533062 | tetraphene | multiple interactions | ISO | Pnma2 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of PNMA2 mRNA | CTD | PMID:27858113 | titanium dioxide | decreases expression | ISO | Pnma2 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of PNMA2 mRNA | CTD | PMID:29264374 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of PNMA2 mRNA | CTD | PMID:33387578 | trichostatin A | increases expression | ISO | PNMA2 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of PNMA2 mRNA | CTD | PMID:24935251 | trichostatin A | multiple interactions | ISO | PNMA2 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PNMA2 mRNA | CTD | PMID:27188386 | trichostatin A | decreases expression | ISO | PNMA2 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of PNMA2 mRNA | CTD | PMID:24935251 and PMID:26272509 | triclosan | decreases expression | ISO | PNMA2 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of PNMA2 mRNA | CTD | PMID:30510588 | triptonide | increases expression | ISO | Pnma2 (Mus musculus) | 6480464 | triptonide results in increased expression of PNMA2 mRNA | CTD | PMID:33045310 | valproic acid | affects expression | ISO | PNMA2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PNMA2 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | PNMA2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PNMA2 mRNA | CTD | PMID:23179753 more ... | zinc sulfate | decreases expression | ISO | PNMA2 (Homo sapiens) | 6480464 | Zinc Sulfate results in decreased expression of PNMA2 mRNA | CTD | PMID:12756304 | |