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Gene: Pccb (propionyl-CoA carboxylase subunit beta) Rattus norvegicus
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Symbol: Pccb
Name: propionyl-CoA carboxylase subunit beta
Description: Predicted to have propionyl-CoA carboxylase activity. Predicted to be involved in cellular amino acid catabolic process and fatty acid catabolic process. Predicted to localize to mitochondrial matrix. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and propionic acidemia. Orthologous to human PCCB (propionyl-CoA carboxylase subunit beta); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC93516; PCCase subunit beta; propanoyl-CoA:carbon dioxide ligase subunit beta; propionyl CoA carboxylase, beta polypeptide; propionyl Coenzyme A carboxylase, beta polypeptide; propionyl-CoA carboxylase beta chain, mitochondrial; propionyl-CoA carboxylase beta subunit
Orthologs:
Homo sapiens (human) : PCCB (propionyl-CoA carboxylase subunit beta)  HGNC  Alliance
Mus musculus (house mouse) : Pccb (propionyl Coenzyme A carboxylase, beta polypeptide)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pccb (propionyl-CoA carboxylase subunit beta)
Pan paniscus (bonobo/pygmy chimpanzee) : PCCB (propionyl-CoA carboxylase subunit beta)
Canis lupus familiaris (dog) : PCCB (propionyl-CoA carboxylase subunit beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pccb (propionyl-CoA carboxylase subunit beta)
Sus scrofa (pig) : PCCB (propionyl-CoA carboxylase subunit beta)
Chlorocebus sabaeus (African green monkey) : PCCB (propionyl-CoA carboxylase subunit beta)
Heterocephalus glaber (naked mole-rat) : Pccb (propionyl-CoA carboxylase subunit beta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08109,368,887 - 109,418,871 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8109,368,624 - 109,418,872 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08108,785,668 - 108,836,131 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48105,946,482 - 105,996,472 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18105,965,673 - 106,015,928 (-)NCBI
Celera8100,982,344 - 101,032,252 (-)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Pccb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3265
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.