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Gene: Acot12 (acyl-CoA thioesterase 12) Rattus norvegicus
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Symbol: Acot12
Name: acyl-CoA thioesterase 12
Description: Exhibits acetyl-CoA hydrolase activity and identical protein binding activity. Involved in acyl-CoA metabolic process. Localizes to the cytosol. Used to study liver cancer. Orthologous to human ACOT12 (acyl-CoA thioesterase 12); PARTICIPATES IN Leigh disease pathway; primary hyperoxaluria type 2 pathway; pyruvate decarboxylase deficiency pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: acetyl-coenzyme A thioesterase; acyl-CoA thioester hydrolase 12; acyl-coenzyme A thioesterase 12; Cach; CACH-1; cytoplasmic acetyl-CoA hydrolase; cytoplasmic acetyl-CoA hydrolase 1; cytosolic acetyl-CoA hydrolase; rACH; rCACH-1
Orthologs:
Homo sapiens (human) : ACOT12 (acyl-CoA thioesterase 12)  HGNC  Alliance
Mus musculus (house mouse) : Acot12 (acyl-CoA thioesterase 12)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acot12 (acyl-CoA thioesterase 12)
Pan paniscus (bonobo/pygmy chimpanzee) : ACOT12 (acyl-CoA thioesterase 12)
Canis lupus familiaris (dog) : ACOT12 (acyl-CoA thioesterase 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acot12 (acyl-CoA thioesterase 12)
Sus scrofa (pig) : ACOT12 (acyl-CoA thioesterase 12)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0220,857,056 - 20,901,656 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl220,857,202 - 20,901,659 (+)Ensembl
Rnor_5.0248,055,053 - 48,096,606 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4221,984,849 - 22,035,224 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1221,905,217 - 21,955,593 (+)NCBI
Celera219,090,138 - 19,130,693 (+)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Acot12
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619752
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.