Psmd1 (proteasome 26S subunit, non-ATPase 1)

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Gene: Psmd1 (proteasome 26S subunit, non-ATPase 1) Rattus norvegicus

Analyze

Symbol:

Psmd1

Name:

proteasome 26S subunit, non-ATPase 1

RGD ID:

621669

Description:

Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of proteasome regulatory particle, base subcomplex. Predicted to be active in nucleus and proteasome storage granule. Orthologous to human PSMD1 (proteasome 26S subunit, non-ATPase 1); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,4-dibromophenyl 2,4,5-tribromophenyl ether; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

26S proteasome non-ATPase regulatory subunit 1; 26S proteasome p112 subunit; 26S proteasome regulatory subunit RPN2; 26S proteasome regulatory subunit S1; 26S proteasome, subunit p112; proteasome (prosome, macropain) 26S subunit, non-ATPase, 1

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PSMD1 (proteasome 26S subunit, non-ATPase 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Psmd1 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Psmd1 (proteasome 26S subunit, non-ATPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PSMD1 (proteasome 26S subunit, non-ATPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PSMD1 (proteasome 26S subunit, non-ATPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Psmd1 (proteasome 26S subunit, non-ATPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PSMD1 (proteasome 26S subunit, non-ATPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PSMD1 (proteasome 26S subunit, non-ATPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Psmd1 (proteasome 26S subunit, non-ATPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	PSMD1 (proteasome 26S subunit, non-ATPase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Psmd1 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	psmd1 (proteasome 26S subunit, non-ATPase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rpn-2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RPN2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Rpn2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	psmd1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	86,709,714 - 86,785,213 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	86,709,947 - 86,785,211 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	95,127,954 - 95,203,203 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	9	100,256,451 - 100,331,701 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	9	98,638,198 - 98,713,509 (+)	NCBI	Rnor_WKY
Rnor_6.0	9	93,080,618 - 93,155,033 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	93,080,615 - 93,155,027 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	92,810,410 - 92,884,825 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	84,807,822 - 84,882,942 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	84,991,240 - 85,066,357 (+)	NCBI
Celera	9	84,130,616 - 84,205,943 (+)	NCBI		Celera
Cytogenetic Map	9	q35	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bardet-Biedl syndrome (ISO)

genetic disease (ISO)

Joubert syndrome 22 (ISO)

Perlman syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane (EXP)

1,2-dichloroethane (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (EXP)

2,6-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

2-nitrofluorene (EXP)

4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one (EXP)

5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (EXP)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

aflatoxin B1 (EXP,ISO)

alpha-pinene (ISO)

amiodarone (EXP)

ammonium chloride (EXP)

aristolochic acid A (ISO)

Aroclor 1254 (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

benzbromarone (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP,ISO)

Brodifacoum (EXP)

cadmium dichloride (EXP)

caffeine (ISO)

clofibrate (EXP)

cobalt dichloride (EXP,ISO)

copper(II) chloride (ISO)

copper(II) sulfate (ISO)

cycloheximide (ISO)

diarsenic trioxide (ISO)

diazinon (EXP)

dibutyl phthalate (EXP)

dieldrin (EXP)

diethylstilbestrol (EXP)

elesclomol (ISO)

enzyme inhibitor (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

fenthion (ISO)

finasteride (EXP)

fipronil (EXP)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

hydralazine (ISO)

hypochlorous acid (ISO)

isoprenaline (EXP)

ivermectin (ISO)

L-ethionine (EXP)

lead(0) (ISO)

lead(2+) (ISO)

leflunomide (EXP)

lithium atom (ISO)

lithium hydride (ISO)

methapyrilene (EXP)

methidathion (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

N-nitrosodimethylamine (EXP)

nefazodone (EXP)

nickel dichloride (EXP)

nimesulide (EXP)

omeprazole (EXP)

oxaliplatin (EXP)

ozone (ISO)

perfluorooctane-1-sulfonic acid (EXP,ISO)

perfluorooctanoic acid (ISO)

phenobarbital (EXP)

piperonyl butoxide (EXP)

pirinixic acid (EXP,ISO)

pregnenolone 16alpha-carbonitrile (EXP)

Propiverine (EXP)

rac-lactic acid (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

thapsigargin (ISO)

thioacetamide (EXP)

topotecan (EXP)

trichloroethene (EXP)

tunicamycin (ISO)

valdecoxib (EXP)

valproic acid (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

proteasome-mediated ubiquitin-dependent protein catabolic process (IBA)

regulation of protein catabolic process (IEA)

Cellular Component

nucleus (IBA)

proteasome accessory complex (ISO,ISS)

proteasome complex (ISO)

proteasome regulatory particle, base subcomplex (IBA,IEA)

proteasome storage granule (IBA)

Molecular Function

enzyme regulator activity (IEA)

protein binding (ISO)

ubiquitin protein ligase binding (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

ubiquitin/proteasome degradation pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Differentially expressed genes in hippocampal cell cultures in response to an excitotoxic insult by quinolinic acid.	Seidel B, etal., Brain Res Mol Brain Res 1998 Oct 1;60(2):296-300.

Additional References at PubMed

PMID:12477932	PMID:16112871	PMID:16207813	PMID:16857966	PMID:16973439	PMID:17323924	PMID:17911097	PMID:17975104	PMID:19946888	PMID:22871113	PMID:23376485	PMID:26316108
PMID:31904090

Genomics

Comparative Map Data

Psmd1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	86,709,714 - 86,785,213 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	86,709,947 - 86,785,211 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	95,127,954 - 95,203,203 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	9	100,256,451 - 100,331,701 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	9	98,638,198 - 98,713,509 (+)	NCBI	Rnor_WKY
Rnor_6.0	9	93,080,618 - 93,155,033 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	93,080,615 - 93,155,027 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	92,810,410 - 92,884,825 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	84,807,822 - 84,882,942 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	84,991,240 - 85,066,357 (+)	NCBI
Celera	9	84,130,616 - 84,205,943 (+)	NCBI		Celera
Cytogenetic Map	9	q35	NCBI

PSMD1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	231,056,867 - 231,172,827 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	2	231,056,845 - 231,173,116 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	231,921,581 - 232,037,541 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	231,629,853 - 231,745,717 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	231,747,113 - 231,862,978	NCBI
Celera	2	225,697,090 - 225,813,040 (+)	NCBI		Celera
Cytogenetic Map	2	q37.1	NCBI
HuRef	2	223,763,642 - 223,879,580 (+)	NCBI		HuRef
CHM1_1	2	231,927,434 - 232,043,006 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	231,541,373 - 231,657,315 (+)	NCBI		T2T-CHM13v2.0

Psmd1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	85,992,341 - 86,067,017 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	85,992,109 - 86,066,873 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	86,064,619 - 86,139,295 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	86,064,387 - 86,139,151 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	87,961,194 - 88,035,870 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	87,895,790 - 87,970,466 (+)	NCBI		MGSCv36	mm8
Celera	1	89,029,935 - 89,104,632 (+)	NCBI		Celera
Cytogenetic Map	1	C5	NCBI

Psmd1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955453	4,314,177 - 4,397,975 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955453	4,314,177 - 4,397,972 (-)	NCBI	ChiLan1.0	ChiLan1.0

PSMD1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	2B	133,698,890 - 133,814,368 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	118,313,158 - 118,428,636 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	237,102,465 - 237,217,364 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	237,102,623 - 237,215,322 (+)	Ensembl	panpan1.1		panPan2

PSMD1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	43,003,127 - 43,096,281 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	43,003,143 - 43,096,271 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	43,563,423 - 43,656,580 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	43,260,096 - 43,353,296 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	43,260,087 - 43,353,277 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	43,188,912 - 43,281,761 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	43,031,707 - 43,124,879 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	43,187,103 - 43,280,333 (+)	NCBI		UU_Cfam_GSD_1.0

Psmd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	185,177,539 - 185,267,963 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936525	5,668,186 - 5,762,364 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936525	5,672,013 - 5,762,035 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PSMD1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	131,807,630 - 131,912,866 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	131,807,594 - 131,912,194 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	145,524,735 - 145,629,782 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PSMD1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	117,078,347 - 117,199,640 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	117,077,881 - 117,197,586 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	82,243,973 - 82,362,878 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Psmd1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624843	4,369,590 - 4,464,287 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624843	4,369,592 - 4,464,285 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Psmd1
300 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	100
Count of miRNA genes:	73
Interacting mature miRNAs:	82
Transcripts:	ENSRNOT00000024306
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10054125	Srcrt7	Stress Responsive Cort QTL 7	3.33	0.0011	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	9	1	87073594	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	25268044	114175309	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	25661188	100929786	Rat
8662828	Vetf6	Vascular elastic tissue fragility QTL 6	3.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	9	36962359	92058970	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	36962359	95410867	Rat
10058949	Gmadr5	Adrenal mass QTL 5	2	0.014	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	9	42791513	87976209	Rat
11353951	Bp394	Blood pressure QTL 394			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	44649921	89649921	Rat
12879506	Pur33	Proteinuria QTL 33			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	44649921	89649921	Rat
11353957	Bmd92	Bone mineral density QTL 92		0.01	tibia mineral mass (VT:1000283)	volumetric bone mineral density (CMO:0001553)	9	46114199	91114199	Rat
631656	Bp108	Blood pressure QTL 108	5.97	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	48598251	93598251	Rat
1578760	Cm53	Cardiac mass QTL 53	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	56771635	101771635	Rat
724515	Uae16	Urinary albumin excretion QTL 16	8		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	58163035	100929646	Rat
1300134	Bp185	Blood pressure QTL 185	3.73		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	61381434	104821652	Rat
1581580	Uae34	Urinary albumin excretion QTL 34			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	62072275	96470995	Rat
1578757	Pur6	Proteinuria QTL 6	3.3	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	62072275	96470995	Rat
61385	Edpm9	Estrogen-dependent pituitary mass QTL 9	3.43	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	63869687	108869687	Rat
731171	Glom6	Glomerulus QTL 6	2.8	0.0003	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	9	64573531	109573531	Rat
1354626	Bvd1	Brain ventricular dilatation QTL 1	3.73	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	9	75712843	111552878	Rat
4889852	Pur26	Proteinuria QTL 26	15	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	77813894	101597663	Rat
7794784	Mcs31	Mammary carcinoma susceptibility QTL 31	2.98		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	9	77813894	111552878	Rat
2303178	Bp334	Blood pressure QTL 334	3.7	0.01	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	79271511	91616855	Rat
2303178	Bp334	Blood pressure QTL 334	3.7	0.01	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	9	79271511	91616855	Rat
2303178	Bp334	Blood pressure QTL 334	3.7	0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	79271511	91616855	Rat
724547	Cm21	Cardiac mass QTL 21	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	9	79271511	102910209	Rat
4889943	Bss90	Bone structure and strength QTL 90	4.1		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	9	86369631	92058970	Rat

Markers in Region

RH131593

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	86,784,185 - 86,784,367 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	93,154,050 - 93,154,231	NCBI	Rnor6.0
Rnor_5.0	9	92,883,842 - 92,884,023	UniSTS	Rnor5.0
RGSC_v3.4	9	84,881,959 - 84,882,140	UniSTS	RGSC3.4
Celera	9	84,204,960 - 84,205,141	UniSTS
Cytogenetic Map	9	q35	UniSTS

PSMD1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	86,729,936 - 86,730,503 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	93,100,646 - 93,101,212	NCBI	Rnor6.0
Rnor_5.0	9	92,830,438 - 92,831,004	UniSTS	Rnor5.0
RGSC_v3.4	9	84,827,888 - 84,828,454	UniSTS	RGSC3.4
Celera	9	84,150,474 - 84,151,040	UniSTS
Cytogenetic Map	9	q35	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	8	11	74	35	41	11	8
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_031978	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084255	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AJ006340	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ007465	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ007476	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC087654	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC105883	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC128734	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC166420	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ218653	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228875	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ234100	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000215	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U57050	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000024306 ⟹ ENSRNOP00000024306

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	86,709,947 - 86,785,211 (+)	Ensembl
Rnor_6.0 Ensembl	9	93,080,615 - 93,155,027 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000089470 ⟹ ENSRNOP00000068871

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	86,716,888 - 86,785,211 (+)	Ensembl
Rnor_6.0 Ensembl	9	93,086,012 - 93,152,691 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000099829 ⟹ ENSRNOP00000086819

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	86,715,328 - 86,785,211 (+)	Ensembl

RefSeq Acc Id:

NM_031978 ⟹ NP_114184

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	86,709,965 - 86,785,213 (+)	NCBI
Rnor_6.0	9	93,080,618 - 93,155,033 (+)	NCBI
Rnor_5.0	9	92,810,410 - 92,884,825 (+)	NCBI
RGSC_v3.4	9	84,807,822 - 84,882,942 (+)	RGD
Celera	9	84,130,616 - 84,205,943 (+)	RGD

Sequence:

show sequence

GATACACTGCGCAGTGGAACGGCGAGTGCAGGGCGCAGCCATGATCACTTCAGCCGCTGGAATT
ATTTCTCTTCTGGATGAAGAAGAGCCACAGCTCAAGGAATTTGCACTACACAAATTGAATGCAG
TTGTGAATGACTTCTGGGCAGAAATTTCTGAGTCTGTAGACAAAATAGAAGTTTTATATGAAGA
TGAAGGTTTCCGCAGTCGGCAGTTTGCAGCCTTGGTGGCATCGAAAGTATTTTATCACCTGGGG
GCTTTCGAGGAGTCTCTGAATTATGCTCTTGGAGCAGGTGACCTCTTCAATGTCAATGATAACT
CTGAATATGTGGAGACTATTATAGCAAAATGCATTGATCATTATACCAAACAGTGTGTGGAAAA
TGCAGATTTGCCTGAAGGAGAAAAGAAGCCAATTGACCAGAGATTGGAAGGCATCGTGAATAAG
ATGTTCCAGCGATGTCTCGATGATCACAAGTATAAGCAAGCGATTGGCATTGCTCTGGAGACCA
GGAGACTAGATGTGTTTGAGAAGACTATACTGGAATCTAATGATGTCCCAGGAATGCTAGCTTA
CAGCCTCAAGCTCTGCATGTCTTTAATGCAGAATAAGCAGTTTCGGAATAAAGTATTGCGAGTC
CTGGTTAAAATCTACATGAACTTGGAAAAACCTGATTTCATCAATGTTTGTCAGTGCTTAATCT
TCTTAGATGACACCCAGGCCGTGAGTGATATCTTAGAAAAGCTGGTAAAGGAAGACAACCTGCT
GATGGCCTATCAGATTTGCTTTGATTTGTACGAAAGTGCCAGCCAGCAGTTTTTGTCATCTGTG
ATCCAGAATCTTCGAACTGTTGGGACCCCTATTGCTTCTGTGCCTGGATCTACCAATACGGGTA
CTGTGCCAGGACCAGAGAAAGACAGTGACTCTATGGAGACCGAGGAGAAGACAGCCGGTGCAGT
GGCAGGGAAAACACCAGACGCTAGTCCAGAGCCCAAGGACCAGACATTGAAAATGATTAAAATT
TTAAGTGGTGAAATGGCTATCGAGTTACACCTGCAGTTCCTAATACGCAATAATAACACAGACC
TCATGATTCTGAAAAACACAAAGGATGCAGTACGAAATTCTGTATGTCATACAGCAACTGTAAT
AGCAAACTCATTCATGCACTGTGGGACTACCAGTGACCAGTTCCTTAGAGATAACTTGGAATGG
CTGGCCAGAGCCACTAACTGGGCCAAATTTACTGCAACTGCCAGCTTGGGTGTAATCCATAAGG
GCCATGAGAAGGAAGCACTACAGTTAATGGCAACATACCTCCCTAAGGACACTTCTCCAGGATC
AGCCTATCAGGAAGGTGGAGGTCTCTATGCATTGGGTCTCATTCATGCCAATCATGGTGGTGAC
ATAATTGACTATCTCCTTAATCAGCTCAAGAATGCCAGCAATGATATCGTTAGACATGGAGGCA
GCTTGGGCCTTGGTTTGGCTGCAATGGGAACTGCACGTCAGGATGTATATGATTTGCTGAAAAC
AAACCTGTATCAGGATGATGCTGTGACAGGGGAGGCAGCTGGCCTGGCCTTAGGTTTGGTTATG
TTAGGCTCTAAAAACACCCAGGCGATTGAGGATATGGTTGGCTATGCACAAGAAACTCAACACG
AGAAGATTCTGCGTGGTCTAGCAGTTGGCATTGCGTTAGTGATGTATGGGAGGATGGAGGAGGC
CGATGCTCTCATTGAATCTCTCTGTCGTGATAAGGACCCAATTCTTAGAAGATCTGGAATGTAT
ACTGTAGCCATGGCTTATTGTGGCTCTGGTAACAATAAAGCTATTCGACGCCTGCTGCATGTTG
CTGTAAGTGATGTCAACGATGATGTCAGAAGAGCAGCAGTAGAGTCTCTTGGCTTCATTTTGTT
CAGGACGCCTGAACAGTGTCCAAGTGTGGTCTCTTTGTTGTCCGAGAGTTATAACCCTCATGTG
CGCTACGGCGCTGCAATGGCCCTGGGAGTCTGCTGTGCTGGTACAGGAAACAAGGAAGCAATTA
ATTTACTGGAGCCAATGACCAATGACCCTGTGAACTACGTGCGGCAAGGGGCTCTGATAGCCTC
AGCTCTCATCATGATCCAACAGACCGAAATCACGTGTCCAAAGGTAAACCAGTTCCGGCAGCTG
TATTCCAAAGTCATCAATGACAAGCATGATGATGTCATGGCCAAATTTGGCGCTATTCTGGCCC
AAGGCATACTGGATGCAGGTGGTCATAATGTCACAATCTCCTTACAGTCCAGGACTGGGCACAC
TCATATGCCTTCTGTGGTTGGCGTCCTTGTCTTTACCCAGTTCTGGTTCTGGTTTCCCCTTTCA
CACTTCCTATCATTGGCTTATACTCCTACCTGTATCATCGGCCTTAACAAGGATTTAAAGATGC
CGAAAGTTCAATATAAATCAAATTGTAAACCATCCACATTCGCATACCCTGCCCCTCTGGAAGT
TCCAAAAGAAAAAGAAAAGGAAAAGGTTTCCACCGCTGTGTTGTCTATTACTGCCAAAGCTAAA
AAAAAAGAAAAAGAAAAAGAAAAAAAGGAGGAGGAGAAGATGGAAGTGGACGAAGCAGAAAAGA
AGGAAGAGAAAGAGAAGAAAAAAGAACCGGAACCAAACTTCCAGCTGTTGGATAATCCAGCACG
GGTCATGCCTGCCCAGCTGAAGGTCTTAAGTATGACAGAGACCTGCAGATACCAACCCTTCAAG
CCACTCTCCATCGGGGGCATCATAATTCTGAAAGACACCAGCGAAGACATTGAGGAACTTGTGG
AACCCGTGGCAGCACATGGCCCAAAGATTGAAGAGGAGGAGCAGGAGCCAGAGCCCCCAGAGCC
ATTTGAGTACATCGATGACTAGGGCCAGGGATCCCACCTGCTCAGCTGTAGATGACTATCCTGG
CACACACTGAAATGTCGTGAGGGAACCCACGCTGAGACCCGCTCGATCCACACATCATTGCCTA
CGCTGACATAAGGAACCCGTGTCCTGAGTCTTTGATTGAGAAGATTCTGACTGTTCAGTGTTCT
CTTTCACAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039084255 ⟹ XP_038940183

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	86,709,714 - 86,785,213 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_114184	(Get FASTA)	NCBI Sequence Viewer
	XP_038940183	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH87654	(Get FASTA)	NCBI Sequence Viewer
	AAI05884	(Get FASTA)	NCBI Sequence Viewer
	AAI28735	(Get FASTA)	NCBI Sequence Viewer
	AAI66420	(Get FASTA)	NCBI Sequence Viewer
	CAA06983	(Get FASTA)	NCBI Sequence Viewer
	CAA07521	(Get FASTA)	NCBI Sequence Viewer
	CAA07524	(Get FASTA)	NCBI Sequence Viewer
	EDL75567	(Get FASTA)	NCBI Sequence Viewer
	EDL75568	(Get FASTA)	NCBI Sequence Viewer
	O88761	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_114184 ⟸ NM_031978

- UniProtKB:

G3V8B6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MITSAAGIISLLDEEEPQLKEFALHKLNAVVNDFWAEISESVDKIEVLYEDEGFRSRQFAALVA
SKVFYHLGAFEESLNYALGAGDLFNVNDNSEYVETIIAKCIDHYTKQCVENADLPEGEKKPIDQ
RLEGIVNKMFQRCLDDHKYKQAIGIALETRRLDVFEKTILESNDVPGMLAYSLKLCMSLMQNKQ
FRNKVLRVLVKIYMNLEKPDFINVCQCLIFLDDTQAVSDILEKLVKEDNLLMAYQICFDLYESA
SQQFLSSVIQNLRTVGTPIASVPGSTNTGTVPGPEKDSDSMETEEKTAGAVAGKTPDASPEPKD
QTLKMIKILSGEMAIELHLQFLIRNNNTDLMILKNTKDAVRNSVCHTATVIANSFMHCGTTSDQ
FLRDNLEWLARATNWAKFTATASLGVIHKGHEKEALQLMATYLPKDTSPGSAYQEGGGLYALGL
IHANHGGDIIDYLLNQLKNASNDIVRHGGSLGLGLAAMGTARQDVYDLLKTNLYQDDAVTGEAA
GLALGLVMLGSKNTQAIEDMVGYAQETQHEKILRGLAVGIALVMYGRMEEADALIESLCRDKDP
ILRRSGMYTVAMAYCGSGNNKAIRRLLHVAVSDVNDDVRRAAVESLGFILFRTPEQCPSVVSLL
SESYNPHVRYGAAMALGVCCAGTGNKEAINLLEPMTNDPVNYVRQGALIASALIMIQQTEITCP
KVNQFRQLYSKVINDKHDDVMAKFGAILAQGILDAGGHNVTISLQSRTGHTHMPSVVGVLVFTQ
FWFWFPLSHFLSLAYTPTCIIGLNKDLKMPKVQYKSNCKPSTFAYPAPLEVPKEKEKEKVSTAV
LSITAKAKKKEKEKEKKEEEKMEVDEAEKKEEKEKKKEPEPNFQLLDNPARVMPAQLKVLSMTE
TCRYQPFKPLSIGGIIILKDTSEDIEELVEPVAAHGPKIEEEEQEPEPPEPFEYIDD

hide sequence

RefSeq Acc Id:

ENSRNOP00000024306 ⟸ ENSRNOT00000024306

RefSeq Acc Id:

ENSRNOP00000068871 ⟸ ENSRNOT00000089470

RefSeq Acc Id:	XP_038940183 ⟸ XM_039084255
- Peptide Label:	isoform X1

RefSeq Acc Id:

ENSRNOP00000086819 ⟸ ENSRNOT00000099829

Protein Domains

26S proteasome regulatory subunit RPN2 C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O88761-F1-model_v2	AlphaFold	O88761	1-953	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696820

Promoter ID:

EPDNEW_R7344

Type:

initiation region

Name:

Psmd1_1

Description:

proteasome 26S subunit, non-ATPase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	93,080,525 - 93,080,585	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621669	AgrOrtholog
BioCyc Gene	G2FUF-26906	BioCyc
Ensembl Genes	ENSRNOG00000017730	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000024306	ENTREZGENE
	ENSRNOP00000024306.4	UniProtKB/TrEMBL
	ENSRNOP00000068871.2	UniProtKB/TrEMBL
	ENSRNOP00000086819.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000024306	ENTREZGENE
	ENSRNOT00000024306.6	UniProtKB/TrEMBL
	ENSRNOT00000089470.2	UniProtKB/TrEMBL
	ENSRNOT00000099829.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.10.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7103375	IMAGE-MGC_LOAD
	IMAGE:7312674	IMAGE-MGC_LOAD
	IMAGE:7313197	IMAGE-MGC_LOAD
	IMAGE:9027749	IMAGE-MGC_LOAD
InterPro	26S_Psome_Rpn2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ARM-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ARM-type_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Proteasome/cyclosome_rpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RPN2_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:83806	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:105383	IMAGE-MGC_LOAD
	MGC:124955	IMAGE-MGC_LOAD
	MGC:156620	IMAGE-MGC_LOAD
	MGC:187355	IMAGE-MGC_LOAD
NCBI Gene	83806	ENTREZGENE
PANTHER	26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR10943:SF2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	HEAT_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PC_rep	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RPN2_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Psmd1	PhenoGen
PIRSF	26S_Psome_Rpn2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF48371	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2JTW5_RAT	UniProtKB/TrEMBL
	A0A8I6A6S3_RAT	UniProtKB/TrEMBL
	A1A5N2_RAT	UniProtKB/TrEMBL
	G3V8B6	ENTREZGENE, UniProtKB/TrEMBL
	O88761	ENTREZGENE, UniProtKB/Swiss-Prot
	Q3KR62_RAT	UniProtKB/TrEMBL
	Q5PPJ7_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-08-19	Psmd1	proteasome 26S subunit, non-ATPase 1	Psmd1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Psmd1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	PSMD1	26S proteasome, subunit p112	Name updated	1299863	APPROVED
2002-08-07	PSMD1	26S proteasome, subunit p112			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in primary hippocampal cells

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)