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Gene: C8b (complement C8 beta chain) Rattus norvegicus
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Symbol: C8b
Name: complement C8 beta chain
Description: Predicted to be involved in complement activation, alternative pathway; complement activation, classical pathway; and cytolysis. Localizes to the extracellular space. Biomarker of myocardial infarction. Human ortholog(s) of this gene implicated in type II complement component 8 deficiency. Orthologous to human C8B (complement C8 beta chain); PARTICIPATES IN coagulation cascade pathway; complement system pathway; Entamoebiasis pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: C8b_mapped; complement component 8 subunit beta; complement component 8, beta polypeptide; complement component 8, beta polypeptide (mapped); complement component 8, beta subunit; complement component C8 beta chain
Orthologs:
Homo sapiens (human) : C8B (complement C8 beta chain)  HGNC  Alliance
Mus musculus (house mouse) : C8b (complement component 8, beta polypeptide)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : C8b (complement C8 beta chain)
Pan paniscus (bonobo/pygmy chimpanzee) : C8B (complement C8 beta chain)
Canis lupus familiaris (dog) : C8B (complement C8 beta chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : C8b (complement C8 beta chain)
Sus scrofa (pig) : C8B (complement C8 beta chain)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05124,298,269 - 124,338,055 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5124,300,477 - 124,338,053 (+)Ensembl
Rnor_5.05128,157,620 - 128,196,920 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45125,728,606 - 125,766,093 (+)NCBIRGSC3.4rn4RGSC3.4
Celera5118,092,231 - 118,129,546 (+)NCBICelera
Cytogenetic Map5q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on C8b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2239
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.