Rnf103 (ring finger protein 103) - Rat Genome Database

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| FTP Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: Rnf103 (ring finger protein 103) Rattus norvegicus

Analyze

Symbol:

Rnf103

Name:

ring finger protein 103

RGD ID:

620586

Description:

Predicted to have ubiquitin-protein transferase activity. Predicted to be involved in protein ubiquitination and ubiquitin-dependent ERAD pathway. Predicted to localize to endoplasmic reticulum. Used to study mental depression. Orthologous to human RNF103 (ring finger protein 103); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

Adrg34; E3 ubiquitin-protein ligase RNF103; Kf1; RING-type E3 ubiquitin transferase RNF103; zfp-103; Zfp103; zinc finger protein 103

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RNF103 (ring finger protein 103)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Rnf103 (ring finger protein 103)	HGNC	EggNOG, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Rnf103 (ring finger protein 103)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RNF103 (ring finger protein 103)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RNF103 (ring finger protein 103)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rnf103 (ring finger protein 103)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RNF103 (ring finger protein 103)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	RNF103 (ring finger protein 103)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rnf103 (ring finger protein 103)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Rnf103 (ring finger protein 103)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Homo sapiens (human):	RNF103 (ring finger protein 103)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	rnf103 (ring finger protein 103)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	4	99,398,479 - 99,415,193 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	99,398,494 - 99,421,164 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	164,178,074 - 164,194,496 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	104,762,184 - 104,778,157 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	4	105,005,938 - 105,022,637 (+)	NCBI
Celera	4	92,685,410 - 92,701,383 (+)	NCBI		Celera
Cytogenetic Map	4	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

juvenile rheumatoid arthritis (ISO)

mental depression (IDA)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (EXP)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

amiodarone (EXP)

ammonium chloride (EXP)

antirheumatic drug (ISO)

benzbromarone (EXP)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP)

calcitriol (ISO)

carbon nanotube (ISO)

ciguatoxin CTX1B (ISO)

clofibrate (EXP)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

dibutyl phthalate (ISO)

dioxygen (ISO)

doxorubicin (ISO)

fipronil (EXP)

flutamide (EXP)

folic acid (ISO)

glafenine (EXP)

isoprenaline (ISO)

L-ethionine (EXP)

leflunomide (ISO)

omeprazole (EXP)

ozone (ISO)

phenobarbital (ISO)

pirinixic acid (EXP,ISO)

propiconazole (ISO)

sertraline (EXP)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sulforaphane (ISO)

tert-butyl hydroperoxide (ISO)

testosterone (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

urethane (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

protein ubiquitination (IBA,IEA,ISO,ISS)

ubiquitin-dependent ERAD pathway (IBA,IEA,ISO)

Cellular Component

endoplasmic reticulum (IBA,IEA,ISO,ISS)

endoplasmic reticulum membrane (IEA)

integral component of membrane (IEA)

Molecular Function

metal ion binding (IEA)

protein binding (ISO)

ubiquitin-protein transferase activity (IBA,IEA,ISO,ISS)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA data from the GO Consortium
3.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
4.	RGD automated data pipeline
5.	RGD automated import pipeline for gene-chemical interactions
6.	Yamada M, etal., Biochem Biophys Res Commun 2000 Nov 11;278(1):150-7.

Additional References at PubMed

PMID:10500182	PMID:12477932	PMID:18675248

Genomics

Comparative Map Data

Rnf103
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	4	99,398,479 - 99,415,193 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	99,398,494 - 99,421,164 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	164,178,074 - 164,194,496 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	104,762,184 - 104,778,157 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	4	105,005,938 - 105,022,637 (+)	NCBI
Celera	4	92,685,410 - 92,701,383 (+)	NCBI		Celera
Cytogenetic Map	4	q31	NCBI

RNF103
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	2	86,603,398 - 86,623,866 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	2	86,603,393 - 86,623,877 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	2	86,830,516 - 86,851,000 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	86,684,027 - 86,704,489 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	2	86,742,174 - 86,762,636	NCBI
Celera	2	86,658,407 - 86,678,870 (-)	NCBI
Cytogenetic Map	2	p11.2	NCBI
HuRef	2	86,728,170 - 86,748,085 (-)	NCBI		HuRef
CHM1_1	2	86,760,437 - 86,780,923 (-)	NCBI		CHM1_1

Rnf103
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	71,470,828 - 71,487,864 (+)	NCBI	GRCm39		mm39
GRCm38	6	71,493,844 - 71,510,880 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	71,493,894 - 71,510,881 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	71,443,888 - 71,460,875 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	6	71,423,403 - 71,440,390 (+)	NCBI			mm8
Celera	6	73,573,253 - 73,590,240 (+)	NCBI		Celera
Cytogenetic Map	6	C1	NCBI
cM Map	6	32.16	NCBI

Rnf103
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955424	1,097,981 - 1,117,844 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955424	1,097,981 - 1,161,267 (+)	NCBI	ChiLan1.0	ChiLan1.0

RNF103
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Mhudiblu_PPA_v0	2A	86,659,672 - 86,680,154 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

RNF103
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	17	38,549,828 - 38,566,149 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	17	38,549,838 - 38,566,613 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Rnf103
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936712	977,650 - 997,623 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RNF103
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	58,161,304 - 58,186,858 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	58,161,087 - 58,183,750 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	60,919,064 - 60,941,736 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RNF103
(Chlorocebus sabaeus - African green monkey)

No map positions available.

Rnf103
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624749	16,689,010 - 16,712,673 (+)	NCBI

Position Markers

AW146237

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	4	99,415,047 - 99,415,126	NCBI	Rnor6.0
Rnor_5.0	4	164,194,350 - 164,194,429	UniSTS	Rnor5.0
RGSC_v3.4	4	104,778,011 - 104,778,090	UniSTS	RGSC3.4
Celera	4	92,701,237 - 92,701,316	UniSTS
Cytogenetic Map	4	q33	UniSTS

RH134592

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	4	99,414,736 - 99,414,929	NCBI	Rnor6.0
Rnor_5.0	4	164,194,039 - 164,194,232	UniSTS	Rnor5.0
RGSC_v3.4	4	104,777,700 - 104,777,893	UniSTS	RGSC3.4
Celera	4	92,700,926 - 92,701,119	UniSTS
Cytogenetic Map	4	q33	UniSTS
RH 3.4 Map	4	630.64	UniSTS

MARC_24177-24178:1033563974:1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	4	99,414,067 - 99,414,725	NCBI	Rnor6.0
Rnor_5.0	4	164,193,370 - 164,194,028	UniSTS	Rnor5.0
RGSC_v3.4	4	104,777,031 - 104,777,689	UniSTS	RGSC3.4
Celera	4	92,700,257 - 92,700,915	UniSTS
Cytogenetic Map	4	q33	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303168	Bp330	Blood pressure QTL 330	4.25	0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	3043231	145254791	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	7850904	182171018	Rat
10755501	Bp390	Blood pressure QTL 390	2.5		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	23850384	169318094	Rat
12798520	Anxrr55	Anxiety related response QTL 55	4.45	0.01	locomotor behavior trait (VT:0001392)	number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)	4	29549895	112807890	Rat
1358352	Srcrt3	Stress Responsive Cort QTL 3	2.29		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	36615599	145611886	Rat
1300139	Hrtrt6	Heart rate QTL 6	2.85		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	4	37703272	115372927	Rat
1576305	Emca6	Estrogen-induced mammary cancer QTL 6	5.8		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	4	43414605	155469929	Rat
1354660	Salc1	Saline consumption QTL 1	11.26		drinking behavior trait (VT:0001422)	saline drink intake rate (CMO:0001627)	4	43414792	146942075	Rat
1354612	Foco1	Food consumption QTL 1	8.87		eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	4	43414792	146942075	Rat
1298082	Stresp4	Stress response QTL 4			blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	46898276	145611886	Rat
2312567	Glom19	Glomerulus QTL 19	1.9	0.006	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	4	49906054	145611886	Rat
70200	Alc18	Alcohol consumption QTL 18	9.2		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	4	55324953	148360954	Rat
1641833	Alc21	Alcohol consumption QTL 21	8.6	0.0001	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	55375865	125671711	Rat
1578657	Bss12	Bone structure and strength QTL 12	8.9		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	4	56092756	101092756	Rat
1578658	Bss13	Bone structure and strength QTL 13	8		femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	4	56092756	101092756	Rat
1358363	Sradr3	Stress Responsive Adrenal Weight QTL 3	6.19		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	4	58166424	103166424	Rat
738009	Sach4	Saccharine consumption QTL 4	4.9	0.000016	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	58640017	154427984	Rat
738016	Alc16	Alcohol consumption QTL 16	3.6	0.00015	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	58640017	154427984	Rat
738031	Alc14	Alcohol consumption QTL 14	7.6	0.00003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	58640017	154427984	Rat
1549839	Bw52	Body weight QTL 52		0.0001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	60439127	113416139	Rat
61418	Pia5	Pristane induced arthritis QTL 5	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	61038901	127777403	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	4	61708341	113100992	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	absolute change in pulse pressure (CMO:0001882)	4	61708341	113100992	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	percent change in systolic blood pressure (CMO:0000747)	4	61708341	113100992	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	percent change in mean arterial blood pressure (CMO:0002035)	4	61708341	113100992	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	61708341	113100992	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	61708341	113100992	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	61708341	113100992	Rat
2300179	Bmd50	Bone mineral density QTL 50	5.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	4	61975371	106975371	Rat
1641919	Alc22	Alcohol consumption QTL 22		0.0005	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	62947687	125671711	Rat
631674	Iddm14	Insulin dependent diabetes mellitus QTL 14			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	4	63537179	157286626	Rat
6478684	Anxrr30	Anxiety related response QTL 30		0.00087	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	63812687	108812687	Rat
6478743	Anxrr40	Anxiety related response QTL 40		0.83076	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	63812687	108812687	Rat
6478772	Anxrr49	Anxiety related response QTL 49		0.15488	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	63812687	108812687	Rat
631651	Bp124	Blood pressure QTL 124	3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	63938412	108938412	Rat
61330	Eau1	Experimental allergic uveoretinitis QTL 1		0.0003	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	4	70773471	132455556	Rat
634344	Hcar7	Hepatocarcinoma resistance QTL 7	7.8		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	4	71476518	116476518	Rat
634344	Hcar7	Hepatocarcinoma resistance QTL 7	7.8		liver integrity trait (VT:0010547)	liver tumorous lesion area to total liver area ratio (CMO:0001075)	4	71476518	116476518	Rat
631646	Stl4	Serum triglyceride level QTL 4	6.5	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	4	73786419	132455556	Rat
724522	Bp146	Blood pressure QTL 146	2.2	0.0021	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	75258970	120258970	Rat
2302051	Pia28	Pristane induced arthritis QTL 28	5.3	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)	4	75258970	120258970	Rat
738015	Pia9	Pristane induced arthritis QTL 9	4.5	0.048	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	76567036	121567036	Rat
70167	Bw22	Body weight QTL 22	3.1		body mass (VT:0001259)	body weight (CMO:0000012)	4	77307388	116916073	Rat
1357342	Bw40	Body weight QTL 40		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	4	77307388	116916073	Rat
631662	Hcar2	Hepatocarcinoma resistance QTL 2	3.1	0.0003	liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	4	79555067	124555067	Rat
631556	Bp135	Blood pressure QTL 135		0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	79557856	116916073	Rat
2306899	Bp338	Blood pressure QTL 338		0.071	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	81874073	119546974	Rat
70177	Xhs1	X-ray hypersensitivity QTL 1	25.1		intestine integrity trait (VT:0010554)	post-insult time to onset of moribundity (CMO:0001896)	4	81959983	152055009	Rat
1576316	Ept5	Estrogen-induced pituitary tumorigenesis QTL 5	3.8		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	4	84475257	178931073	Rat
634334	Xhs3	X-ray hypersensitivity QTL 3	10		intestine integrity trait (VT:0010554)	post-insult time to onset of moribundity (CMO:0001896)	4	85794049	129615056	Rat
1582232	Gluco25	Glucose level QTL 25	3.6	0.0023	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	86312589	146942261	Rat
12798523	Anxrr56	Anxiety related response QTL 56	2.83	0.05	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	86312589	147702403	Rat
1358202	Gluco11	Glucose level QTL 11	2.4	0.02	adipocyte glucose uptake trait (VT:0004185)	absolute change in adipocyte glucose uptake (CMO:0000873)	4	86438317	168047091	Rat
61476	Aia3	Adjuvant induced arthritis QTL 3	3.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	86532519	131532519	Rat
1578662	Bss15	Bone structure and strength QTL 15	19.6		femur width (VT:1000666)	femoral neck width (CMO:0001695)	4	87136446	132136446	Rat
1578670	Bss14	Bone structure and strength QTL 14	16.4		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	4	87136446	132136446	Rat
631689	Scl4	Serum cholesterol level QTL 4	1.9	0.008	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	4	94414208	139414208	Rat
634335	Anxrr16	Anxiety related response QTL 16	7.22		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	4	94893247	168046938	Rat
8662350	Eae35	Experimental allergic encephalomyelitis QTL 35	6.2		blood tumor necrosis factor amount (VT:0008552)	inflammatory exudate tumor necrosis factor level (CMO:0001435)	4	98500164	99633958	Rat
61434	Cia3	Collagen induced arthritis QTL 3	4.8		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	99066823	144066823	Rat
2317588	Eae27	Experimental allergic encephalomyelitis QTL 27			nervous system integrity trait (VT:0010566)	percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)	4	99066972	110635449	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	48
Count of miRNA genes:	39
Interacting mature miRNAs:	48
Transcripts:	ENSRNOT00000064374
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	29	57	41	18	41	8	10	72	35	37	11	8
Low		14			1			1	2		4
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053438	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236653	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AABR07060895	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01030769	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF306394	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC100629	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473957	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000064374 ⟹ ENSRNOP00000062726

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	4	99,398,494 - 99,415,192 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000088018 ⟹ ENSRNOP00000072898

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	4	99,399,148 - 99,421,164 (+)	Ensembl

RefSeq Acc Id:

NM_053438 ⟹ NP_445890

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	99,399,220 - 99,415,193 (+)	NCBI
Rnor_5.0	4	164,178,074 - 164,194,496 (+)	NCBI
RGSC_v3.4	4	104,762,184 - 104,778,157 (+)	RGD
Celera	4	92,685,410 - 92,701,383 (+)	RGD

Sequence:

show sequence

CGGCTCCCGGCGACGCCAAGAGGGCGAAGATGTGGCTGAAGCTGTTTTTCTTGCTCCTGTATTT
CCTGATCCTGTTCGTCCTGGCCAGGTTTTTTGAGGCCATTGTGTGGTACGAGACTGGCATCTTT
GCTACTCAGCTGGTGGATCCGGTGGCATTGAGCTTCAAGAAGCTGAAGACCATTCTGGAGTGTC
GAGGGCTGGGCTACTCCGGACTACCTGAGAAGAAAGATGTACGGGAGCTGGTGGAGAAGTCAGG
TGACTTGATGGAAGGTGAACTCTATTCTGCTCTCAAGGAAGAAGAAGCATCTGAGTCTGTTTCT
AGTACCAATTTCAGTGGTGAAATGCATTTCTATGAGCTTGTAGAAGACACAAAAGATGGCATCT
GGCTGGTTCAGGTCATAGCAAATGACAGAAGTCCTTTGGTGGGTAAAATCCACTGGGAGAAAAT
GGTAAAAAAAGTGTCAAGATTTGGAATACGGACAGGCACTTTCAACTGTTCCAGTGATCCCAGG
TACTGCAGAAGGAGAGGCTGGGTACGTTCCACTCTCATCATGTCTGTCCCACAAACAAGCACAT
CTAAAGGGAAAGTCATGCTTAAAGAGTACAGTGGGCGCAAGATTGAAGTAGAACACATTTTTAA
ATGGATAACTGCCCATGCAGCTTCTCGGATCAAAACTATATATAATGTTGAGCATTTGAAAGAA
GAATGGAATAAAAGTGATCAGTACTGGGTAAAAATATACCTGTTTGCAAACCTTGACCAACCAC
CAGCTTTCTTCTCTGCATTAAGTATAAAATTTACTGGAAGAGTTGAGTTTATTTTTGTTAATGT
GGAAAATTGGAACAACAAGAGTTATATGACAGATATTGGTATTTATAACATGCCGTCATACATA
CTTAGAACTCCTGAAGGAATTTACAGATATGGAAATCACACAGGTGAATTTATATCCCTTCAGG
CCATGGATTCATTTTTACGCTCATTACAACCTGAAGTAAATGATCTGTTTGTTTTGAGTTTGGT
TCTAGTTAATCTTATGGCTTGGATGGACTTATTTATTACACAAGGAGCAACCATCAAGCGATTT
GTGGTTCTCATAAGCACTTTAGGGACATACAATTCCCTATTAATTATTTCTTGGCTACCTGTGT
TGGGCTTTCTACAGCTCCCTTACTTAGATAGCTTTTATGAATATAGTTTAAGATTGCTGCGATA
CTCTAATACAACCACACTGGCTTCGTGGGTAAGGGCAGACTGGATGTTTTACTCTTCACACCCA
GCCCTGTTTCTCAGTACATACCTTGGACATGGTTTGCTAATTGATTACTTTGAGAAGAAGAGAC
GGCGCAGCAACAATGATGAAGTTAATGCGAATAATTTAGAGTGGTTATCAAGTCTGTGGGACTG
GTACACCAGCTACCTCTTCCACCCGATTGCTTCTTTTCAGAACTTTCCTGTAGACTCTGATTGG
GATGAAGACCCTGACTTATTCTTGGAGCGGTTAGCTTTCCCTGACCTTTGGCTTCACCCTCTGA
TACCAACTGATTATATTAAAAACTTACCAATGTGGCGGTTTAAATGTCTTGGGGCTCAGTCTGA
AGAAGAAATGTCGGAGAGTTCTCAAGACACTGAAAATGACTCAGATAGTGACAACACGGACACT
TTTAGTAGTAGTAAGGATGTATTTGAAGATAAACAAAATGTTCACAGTTCTCCAGGAAGAACAA
GTCGCTGCGATACTGAGGCTTGTTCATGTGCCAATAAATGTTGTCAGACCAGCCCATGTGAAAG
GAAGAGGAGGTCATATGGCTCACATAATACTAAGGAAGATATGGAGCCGGACTGGCTAACTTGG
CCTGCTGGTACGCTGCACTGTACTGAATGTGTTGTTTGCCTTGAGAATTTTGAGAATGGATGTT
TGCTGATGGGGTTGCCTTGTGGTCATGTGTTTCACCAGAATTGCATTGTTATGTGGTTGGCTGG
GGGCCGACACTGTTGCCCTGTTTGCCGTTGGCCTTCATATAAGAAAAAGCAGCCATATGCACAG
CAACAGCCGTTGTCAAATGATGCTCCATCTTGACCATGTGCAGTTGTCCAATAAGCTTTGAGTA
TCTTACAGCTTGCCTTTTTAATGTTAGTCACAATGTTTTTGTGGTTTGAAGTTTAGTTTAATGT
TAGTGCAGTGACAGGAAATACACATTATGCTGATGTTGATGACAGAATTTATTTGGATGCCTTG
TGTGTCAATTGAATGCATACTAAACTGTAAAAAAATTATTTACAGCATTGAAAATTCAGAAGTT
AATGGGTTTTTTGTAAGCACAAAAGAGGTATGGTAGAAATTTATCTTAGCAAGACTTTATGAGG
CAGGATCAAATCCTAGTGGGCCTGAGCTGATTTCTTACCCTAAATGTTTTTTCCCTTTTTACAA
TCTCTGTCCAGCACCTCTTGGTTAAATAATGTATGCTCTGAGACATGAAATTAAAACAGATCTA
TAAAATAAATTATTTTAAAAGCAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006236653 ⟹ XP_006236715

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	99,398,479 - 99,415,193 (+)	NCBI
Rnor_5.0	4	164,178,074 - 164,194,496 (+)	NCBI

Sequence:

show sequence

CCAGTGCTCCGGGGGCGACGGCCGTGGCCTGAGGAGGCGGCAGGGACGGTGGCCGCGGTTGGCG
CGGCGCATCCGCACAGGGCTAGTCCCCGCGCAGCTACGCAACTGACAGGAAGCCTCCCTGGAGA
GCCGCGTCGGGGCCTAGTGTTATTTGCTTTTTGCTTTTTCTCCCTTCACGACTGTGGTCTCGCG
CTCTTCCTCAGCGGGAGCCGCCGCGACGCCCCCTCGCGGGCCGCCGGCCTGAGAGGCGCCGCCC
GCGGGAACCTGGAGCCGCCGCCGGGCCTGGGCGGCCGCCGGGGCCTGAAGCCTGGGCGTTCGGC
GCGGCGCTGCGACGACCGCTCCAACCCGCGCTGGGCGCGCCGGGCCCCAGGCCTGGCCCAGCCG
AGCACCGCGCCTTCCGGACTGGGGCCACGTAGTCCGGCGCCAACCGCCCTCCGCTGGCCCGCAG
TCTATCGGAGCTGCCTCCTGGGTCACCCCTGGTGGGCTCTTGCCCCTTCCAGCCTTCCGCGGTT
CGATGGGTGGAGTGCTTTTGAACGTACCCTCTTCTCCCTTTCTCAGCTCTTGACCGCAAGGCCA
GAGCCGGCGCCCTCAGCCGCACGCACGCAGCGATCCACCTGCCTCCCCGCGGGGATGGCCCGCG
GGTGACCGCCACCGCCGCGCGCCCTCGCTGCCCTCGCCGCCCTCGCCCAGGCTACGCTCCGTCG
CCCCGCACTCGACCCCCTCTTCTTGTCCACGGCGTCCCGGCTCCCGGCGACGCCAAGAGGGCGA
AGATGTGGCTGAAGCTGTTTTTCTTGCTCCTGTATTTCCTGATCCTGTTCGTCCTGGCCAGGTT
TTTTGAGGCCATTGTGTGGTACGAGACTGGCATCTTTGCTACTCAGCTGGTGGATCCGGTGGCA
TTGAGCTTCAAGAAGCTGAAGACCATTCTGGAGTGTCGAGGGCTGGGCTACTCCGGACTACCTG
AGAAGAAAGATGTACGGGAGCTGGTGGAGAAGTCAGGTGACTTGATGGAAGGTGAACTCTATTC
TGCTCTCAAGGAAGAAGAAGCATCTGAGTCTGTTTCTAGTACCAATTTCAGTGGTGAAATGCAT
TTCTATGAGCTTGTAGAAGACACAAAAGATGGCATCTGGCTGGTTCAGGTCATAGCAAATGACA
GAAGTCCTTTGGTGGGTAAAATCCACTGGGAGAAAATGGTAAAAAAAGTGTCAAGATTTGGAAT
ACGGACAGGCACTTTCAACTGTTCCAGTGATCCCAGTTTACTCTCTTACAGGTACTGCAGAAGG
AGAGGCTGGGTACGTTCCACTCTCATCATGTCTGTCCCACAAACAAGCACATCTAAAGGGAAAG
TCATGCTTAAAGAGTACAGTGGGCGCAAGATTGAAGTAGAACACATTTTTAAATGGATAACTGC
CCATGCAGCTTCTCGGATCAAAACTATATATAATGTTGAGCATTTGAAAGAAGAATGGAATAAA
AGTGATCAGTACTGGGTAAAAATATACCTGTTTGCAAACCTTGACCAACCACCAGCTTTCTTCT
CTGCATTAAGTATAAAATTTACTGGAAGAGTTGAGTTTATTTTTGTTAATGTGGAAAATTGGAA
CAACAAGAGTTATATGACAGATATTGGTATTTATAACATGCCGTCATACATACTTAGAACTCCT
GAAGGAATTTACAGATATGGAAATCACACAGGTGAATTTATATCCCTTCAGGCCATGGATTCAT
TTTTACGCTCATTACAACCTGAAGTAAATGATCTGTTTGTTTTGAGTTTGGTTCTAGTTAATCT
TATGGCTTGGATGGACTTATTTATTACACAAGGAGCAACCATCAAGCGATTTGTGGTTCTCATA
AGCACTTTAGGGACATACAATTCCCTATTAATTATTTCTTGGCTACCTGTGTTGGGCTTTCTAC
AGCTCCCTTACTTAGATAGCTTTTATGAATATAGTTTAAGATTGCTGCGATACTCTAATACAAC
CACACTGGCTTCGTGGGTAAGGGCAGACTGGATGTTTTACTCTTCACACCCAGCCCTGTTTCTC
AGTACATACCTTGGACATGGTTTGCTAATTGATTACTTTGAGAAGAAGAGACGGCGCAGCAACA
ATGATGAAGTTAATGCGAATAATTTAGAGTGGTTATCAAGTCTGTGGGACTGGTACACCAGCTA
CCTCTTCCACCCGATTGCTTCTTTTCAGAACTTTCCTGTAGACTCTGATTGGGATGAAGACCCT
GACTTATTCTTGGAGCGGTTAGCTTTCCCTGACCTTTGGCTTCACCCTCTGATACCAACTGATT
ATATTAAAAACTTACCAATGTGGCGGTTTAAATGTCTTGGGGCTCAGTCTGAAGAAGAAATGTC
GGAGAGTTCTCAAGACACTGAAAATGACTCAGATAGTGACAACACGGACACTTTTAGTAGTAGT
AAGGATGTATTTGAAGATAAACAAAATGTTCACAGTTCTCCAGGAAGAACAAGTCGCTGCGATA
CTGAGGCTTGTTCATGTGCCAATAAATGTTGTCAGACCAGCCCATGTGAAAGGAAGAGGAGGTC
ATATGGCTCACATAATACTAAGGAAGATATGGAGCCGGACTGGCTAACTTGGCCTGCTGGTACG
CTGCACTGTACTGAATGTGTTGTTTGCCTTGAGAATTTTGAGAATGGATGTTTGCTGATGGGGT
TGCCTTGTGGTCATGTGTTTCACCAGAATTGCATTGTTATGTGGTTGGCTGGGGGCCGACACTG
TTGCCCTGTTTGCCGTTGGCCTTCATATAAGAAAAAGCAGCCATATGCACAGCAACAGCCGTTG
TCAAATGATGCTCCATCTTGACCATGTGCAGTTGTCCAATAAGCTTTGAGTATCTTACAGCTTG
CCTTTTTAATGTTAGTCACAATGTTTTTGTGGTTTGAAGTTTAGTTTAATGTTAGTGCAGTGAC
AGGAAATACACATTATGCTGATGTTGATGACAGAATTTATTTGGATGCCTTGTGTGTCAATTGA
ATGCATACTAAACTGTAAAAAAATTATTTACAGCATTGAAAATTCAGAAGTTAATGGGTTTTTT
GTAAGCACAAAAGAGGTATGGTAGAAATTTATCTTAGCAAGACTTTATGAGGCAGGATCAAATC
CTAGTGGGCCTGAGCTGATTTCTTACCCTAAATGTTTTTTCCCTTTTTACAATCTCTGTCCAGC
ACCTCTTGGTTAAATAATGTATGCTCTGAGACATGAAATTAAAACAGATCTATAAAATAAATTA
TTTTAAAAGCA

hide sequence

Protein Sequences


Protein RefSeqs	NP_445890	(Get FASTA)	NCBI Sequence Viewer
	XP_006236715	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAG37065	(Get FASTA)	NCBI Sequence Viewer
	AAI00630	(Get FASTA)	NCBI Sequence Viewer
	EDL90994	(Get FASTA)	NCBI Sequence Viewer
	EDL90996	(Get FASTA)	NCBI Sequence Viewer
	Q9EPZ8	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_445890 ⟸ NM_053438

- UniProtKB:

Q497B6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MWLKLFFLLLYFLILFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPE
KKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDR
SPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEY
SGRKIEVEHIFKWITAHAASRIKTIYNVEHLKEEWNKSDQYWVKIYLFANLDQPPAFFSALSIK
FTGRVEFIFVNVENWNNKSYMTDIGIYNMPSYILRTPEGIYRYGNHTGEFISLQAMDSFLRSLQ
PEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLD
SFYEYSLRLLRYSNTTTLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRSNNDEVNA
NNLEWLSSLWDWYTSYLFHPIASFQNFPVDSDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLP
MWRFKCLGAQSEEEMSESSQDTENDSDSDNTDTFSSSKDVFEDKQNVHSSPGRTSRCDTEACSC
ANKCCQTSPCERKRRSYGSHNTKEDMEPDWLTWPAGTLHCTECVVCLENFENGCLLMGLPCGHV
FHQNCIVMWLAGGRHCCPVCRWPSYKKKQPYAQQQPLSNDAPS

hide sequence

RefSeq Acc Id:

XP_006236715 ⟸ XM_006236653

- Peptide Label:

isoform X1

- Sequence:

show sequence

MWLKLFFLLLYFLILFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPE
KKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDR
SPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPSLLSYRYCRRRGWVRSTLIMSVPQTSTSKGKV
MLKEYSGRKIEVEHIFKWITAHAASRIKTIYNVEHLKEEWNKSDQYWVKIYLFANLDQPPAFFS
ALSIKFTGRVEFIFVNVENWNNKSYMTDIGIYNMPSYILRTPEGIYRYGNHTGEFISLQAMDSF
LRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQ
LPYLDSFYEYSLRLLRYSNTTTLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRSNN
DEVNANNLEWLSSLWDWYTSYLFHPIASFQNFPVDSDWDEDPDLFLERLAFPDLWLHPLIPTDY
IKNLPMWRFKCLGAQSEEEMSESSQDTENDSDSDNTDTFSSSKDVFEDKQNVHSSPGRTSRCDT
EACSCANKCCQTSPCERKRRSYGSHNTKEDMEPDWLTWPAGTLHCTECVVCLENFENGCLLMGL
PCGHVFHQNCIVMWLAGGRHCCPVCRWPSYKKKQPYAQQQPLSNDAPS

hide sequence

RefSeq Acc Id:

ENSRNOP00000062726 ⟸ ENSRNOT00000064374

RefSeq Acc Id:

ENSRNOP00000072898 ⟸ ENSRNOT00000088018

Protein Domains

RING-type

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693114

Promoter ID:

EPDNEW_R3639

Type:

multiple initiation site

Name:

Rnf103_1

Description:

ring finger protein 103

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	99,398,481 - 99,398,541	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620586	AgrOrtholog
Ensembl Genes	ENSRNOG00000007272	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000062726	UniProtKB/TrEMBL
	ENSRNOP00000072898	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000064374	UniProtKB/TrEMBL
	ENSRNOT00000088018	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	3.30.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7938106	IMAGE-MGC_LOAD
InterPro	RNF103	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_RING	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:84508	UniProtKB/TrEMBL
MGC_CLONE	MGC:124587	IMAGE-MGC_LOAD
NCBI Gene	84508	ENTREZGENE
PANTHER	PTHR15302	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	zf-RING_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Rnf103	PhenoGen
PROSITE	ZF_RING_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	RING	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene	Rn.45685	ENTREZGENE
UniProt	A0A0G2K441_RAT	UniProtKB/TrEMBL
	F1LNY7_RAT	UniProtKB/TrEMBL
	Q497B6	ENTREZGENE, UniProtKB/TrEMBL
	Q9EPZ8	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Rnf103	ring finger protein 103	Zfp103	zinc finger protein 103	Symbol and Name updated	1299863	APPROVED
2002-08-07	Zfp103	zinc finger protein 103			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_domains	contains a C-terminal RING-H2 finger motif	634523

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD