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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:streptozocin
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Accession:CHEBI:9288 term browser browse the term
Definition:An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Synonyms:exact_synonym: 2-deoxy-2-{[methyl(nitroso)carbamoyl]amino}-alpha-D-glucopyranose
 related_synonym: 2-Deoxy-2-(((methylnitrosoamino)carbonyl)amino)-D-glucopyranose;   2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose;   Formula=C8H15N3O7;   InChI=1S/C8H15N3O7/c1-11(10-17)8(16)9-4-6(14)5(13)3(2-12)18-7(4)15/h3-7,12-15H,2H2,1H3,(H,9,16)/t3-,4-,5-,6-,7+/m1/s1;   InChIKey=ZSJLQEPLLKMAKR-GKHCUFPYSA-N;   N-D-Glucosyl-(2)-N'-nitrosomethylharnstoff;   N-D-Glucosyl-(2)-N'-nitrosomethylurea;   SMILES=CN(N=O)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O;   Streptozocinium;   Streptozotocin;   Zanosar;   estreptozocina;   streptozocine;   streptozocinum
 xref: Beilstein:2060675;   CAS:18883-66-4;   DrugBank:DB00428;   HMDB:HMDB0014572;   KEGG:C07313;   KEGG:D05932
 xref_mesh: MESH:D013311
 xref: PMID:12613763;   PMID:23151907;   PMID:23333576;   PMID:23600389;   PMID:23612842;   PMID:23662406;   PMID:2954873;   Patent:FR1434920;   Patent:US2005271747;   Patent:US2005272738;   Patent:US2008085882;   Patent:US4156777;   Reaxys:2060675;   Wikipedia:Streptozocin


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streptozocin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of A2M mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of A2M mRNA] CTD PMID:33484791 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions EXP [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of ABCA1 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of ABCA1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of ABCA1 mRNA CTD PMID:35786680 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 increases activity
increases expression		 EXP
ISO		 Streptozocin results in increased activity of ABCB11 protein
Streptozocin results in increased expression of ABCB11 protein		 CTD PMID:12055592 PMID:23319174 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B decreases expression
increases expression		 ISO Streptozocin results in decreased expression of ABCB1B mRNA; Streptozocin results in decreased expression of ABCB1B protein
Streptozocin results in increased expression of ABCB1B protein		 CTD PMID:22531820 PMID:23319174 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression EXP Streptozocin results in increased expression of ABCB4 mRNA; Streptozocin results in increased expression of ABCB4 protein CTD PMID:12055592 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO Streptozocin results in increased expression of ABCC1 mRNA; Streptozocin results in increased expression of ABCC1 protein CTD PMID:22531820 PMID:23319174 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP
ISO		 Streptozocin results in increased expression of ABCC2 mRNA
Streptozocin results in increased expression of ABCC2 mRNA; Streptozocin results in increased expression of ABCC2 protein		 CTD PMID:11752103 PMID:22531820 PMID:23319174 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression
multiple interactions
increases expression		 ISO
EXP		 Streptozocin results in decreased expression of ABCC3 mRNA
[resveratrol co-treated with Streptozocin] results in increased expression of ABCC3 mRNA
Streptozocin results in increased expression of ABCC3 mRNA; Streptozocin results in increased expression of ABCC3 protein		 CTD PMID:22531820 PMID:23319174 PMID:25905778 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression
multiple interactions		 ISO Streptozocin results in increased expression of ABCC4 mRNA; Streptozocin results in increased expression of ABCC4 protein
[Dietary Fats co-treated with Streptozocin] results in increased expression of ABCC4 mRNA		 CTD PMID:22531820 PMID:23319174 PMID:29382564 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 increases expression ISO Streptozocin results in increased expression of ABCC5 mRNA; Streptozocin results in increased expression of ABCC5 protein CTD PMID:22531820 PMID:23319174 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 decreases expression ISO Streptozocin results in decreased expression of ABCC6 protein CTD PMID:22531820 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO Streptozocin results in increased expression of ABCG2 mRNA; Streptozocin results in increased expression of ABCG2 protein CTD PMID:23319174 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression ISO Streptozocin results in increased expression of ABCG5 mRNA CTD PMID:23319174 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression ISO Streptozocin results in increased expression of ABCG8 mRNA CTD PMID:23319174 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912 		JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ABHD2 mRNA CTD PMID:29127188 NCBI chr 1:133,217,403...133,298,564
Ensembl chr 1:133,217,375...133,299,061 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions
increases expression
decreases expression
decreases activity		 EXP
ISO		 Fructose inhibits the reaction [Streptozocin results in decreased activity of ACACA protein]; Fructose inhibits the reaction [Streptozocin results in decreased expression of ACACA mRNA]; Triiodothyronine inhibits the reaction [Streptozocin results in decreased activity of ACACA protein]; Triiodothyronine inhibits the reaction [Streptozocin results in decreased expression of ACACA mRNA]
[Dietary Fats co-treated with Streptozocin] results in increased expression of ACACA mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ACACA mRNA]
Streptozocin results in increased expression of ACACA mRNA		 CTD PMID:1973097 PMID:28822685 PMID:33812996 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of ACADM protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ACADM protein]		 CTD PMID:19634143 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147 		JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in decreased expression of ACAT1 protein
Streptozocin results in decreased expression of ACAT1 mRNA
Acrylamide inhibits the reaction [Streptozocin results in decreased expression of ACAT1 mRNA]
Trientine inhibits the reaction [Streptozocin results in decreased expression of ACAT1 protein]		 CTD PMID:19634143 PMID:34896238 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
G Acbd6 acyl-CoA binding domain containing 6 increases expression EXP Streptozocin results in increased expression of ACBD6 mRNA CTD PMID:25905778 NCBI chr13:67,726,786...67,863,392
Ensembl chr13:67,726,786...67,862,311 		JBrowse link
G Ace angiotensin I converting enzyme multiple interactions
increases expression
increases activity		 EXP
ISO		 [INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ACE protein]
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of ACE mRNA]; [Streptozocin co-treated with Niacinamide] results in increased expression of ACE mRNA; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of ACE mRNA]
Streptozocin results in increased activity of ACE protein
Streptozocin results in increased expression of ACE mRNA; Streptozocin results in increased expression of ACE protein		 CTD PMID:15793251 PMID:16979161 PMID:22191573 PMID:23733546 PMID:28468961 More... NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression
increases activity
multiple interactions		 ISO
EXP		 Streptozocin results in decreased expression of ACE2 protein
Streptozocin results in increased activity of ACE2 protein
[INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]; ACE2 inhibits the reaction [Streptozocin results in increased expression of AGT protein modified form]; ACE2 inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; ACE2 inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of ACE2 mRNA]; [Streptozocin co-treated with Niacinamide] results in decreased expression of ACE2 mRNA; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of ACE2 mRNA]; Telmisartan inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]		 CTD PMID:20844835 PMID:21381899 PMID:28468961 PMID:29266779 PMID:29682576 More... NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Acer2 alkaline ceramidase 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of ACER2 mRNA CTD PMID:25905778 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614 		JBrowse link
G Ache acetylcholinesterase multiple interactions
decreases activity
increases activity		 ISO
EXP		 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Lisinopril inhibits the reaction [Streptozocin results in increased activity of ACHE protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Telmisartan inhibits the reaction [Streptozocin results in increased activity of ACHE protein]]; Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Alendronate inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Curcumin inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Donepezil inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Genistein inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Indinavir inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Lisinopril inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Physostigmine inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Telmisartan inhibits the reaction [Streptozocin results in increased activity of ACHE protein]
Streptozocin results in decreased activity of ACHE protein
[Fructose co-treated with Streptozocin] results in increased expression of ACHE protein; [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in decreased activity of ACHE protein; [Propolis co-treated with Streptozocin] inhibits the reaction [Chlorpyrifos results in decreased activity of ACHE protein]; [Streptozocin co-treated with Chlorpyrifos] results in decreased activity of ACHE protein; [Streptozocin co-treated with Dietary Fats] results in increased activity of ACHE protein; alpha-Tocopherol inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Canagliflozin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of ACHE protein]; Chlorpyrifos inhibits the reaction [Streptozocin results in decreased activity of ACHE protein]; Donepezil inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; geraniol inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Melatonin inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Metformin inhibits the reaction [[Fructose co-treated with Streptozocin] results in increased expression of ACHE protein]; Phycocyanin inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in decreased activity of ACHE protein]; Propolis inhibits the reaction [Streptozocin results in decreased activity of ACHE protein]; pyrazolanthrone inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Rivastigmine inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Streptozocin inhibits the reaction [Chlorpyrifos results in decreased activity of ACHE protein]; Streptozocin promotes the reaction [[Propolis co-treated with Chlorpyrifos] results in decreased activity of ACHE protein]; Tocotrienols inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; vanillin inhibits the reaction [[Fructose co-treated with Streptozocin] results in increased expression of ACHE protein]		 CTD PMID:18208924 PMID:18343489 PMID:19464315 PMID:19705549 PMID:20369229 More... NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase increases activity
increases expression		 EXP Streptozocin results in increased activity of ACMSD protein
Streptozocin results in increased expression of ACMSD mRNA		 CTD PMID:12042425 NCBI chr13:39,200,412...39,245,954
Ensembl chr13:39,200,314...39,245,209 		JBrowse link
G Aco2 aconitase 2 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of ACO2 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ACO2 protein]		 CTD PMID:19634143 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261 		JBrowse link
G Acot1 acyl-CoA thioesterase 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ACOT1 mRNA CTD PMID:29127188 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 multiple interactions EXP
ISO		 [resveratrol co-treated with Streptozocin] results in decreased expression of ACOT2 mRNA
[Streptozocin co-treated with Dietary Fats] results in increased expression of ACOT2 mRNA		 CTD PMID:25905778 PMID:29127188 NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245 		JBrowse link
G Acot9 acyl-CoA thioesterase 9 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ACOT9 mRNA CTD PMID:29127188 NCBI chr  X:40,073,197...40,123,573
Ensembl chr  X:40,064,810...40,123,559 		JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions EXP [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of ACOX1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of ACOX1 mRNA CTD PMID:35786680 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant increases expression
increases activity
multiple interactions		 ISO Streptozocin results in increased expression of ACP5 mRNA
Streptozocin results in increased activity of ACP5 protein
formononetin inhibits the reaction [Streptozocin results in increased activity of ACP5 protein]; formononetin inhibits the reaction [Streptozocin results in increased expression of ACP5 mRNA]		 CTD PMID:35315182 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Acsm2 acyl-CoA synthetase medium-chain family member 2 increases expression EXP Streptozocin results in increased expression of ACSM2 mRNA CTD PMID:25905778 NCBI chr 1:173,916,368...173,955,116
Ensembl chr 1:173,916,368...173,955,116 		JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ACSS1 mRNA CTD PMID:29127188 NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
decreases expression
increases expression		 EXP
ISO		 [Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein]; Metformin promotes the reaction [dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein]]
Streptozocin results in decreased expression of ACTA2 protein
Streptozocin results in increased expression of ACTA2 protein
[Dietary Fats co-treated with Streptozocin] results in increased expression of ACTA2 mRNA; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of ACTA2 mRNA]; [Streptozocin co-treated with fatostatin] results in increased expression of ACTA2 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of ACTA2 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of ACTA2 protein; bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ACTA2 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ACTA2 mRNA]		 CTD PMID:29420703 PMID:29988851 PMID:30551545 PMID:35051763 PMID:35993117 More... NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 decreases expression EXP Streptozocin results in decreased expression of ACTC1 protein CTD PMID:21136691 NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523 		JBrowse link
G Actn4 actinin alpha 4 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ACTN4 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ACTN4 protein]		 CTD PMID:19634143 NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847 		JBrowse link
G Acy1 aminoacylase 1 multiple interactions
decreases expression		 EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of ACY1 protein] CTD PMID:19634143 NCBI chr 8:107,072,354...107,077,756
Ensembl chr 8:107,072,358...107,077,682 		JBrowse link
G Ada adenosine deaminase increases activity
multiple interactions		 EXP Streptozocin results in increased activity of ADA protein
[Zinc Sulfate results in increased abundance of Zinc] inhibits the reaction [Streptozocin results in increased activity of ADA protein]		 CTD PMID:32864810 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ADAM17 mRNA; Streptozocin results in increased expression of ADAM17 protein
Diosgenin inhibits the reaction [Streptozocin results in increased expression of ADAM17 mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of ADAM17 protein]		 CTD PMID:35305976 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 multiple interactions
increases expression		 EXP
ISO		 stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased expression of ADGRE1 protein]]
Streptozocin results in increased expression of ADGRE1 mRNA
[fatostatin co-treated with Streptozocin] results in increased expression of ADGRE1 mRNA		 CTD PMID:23611540 PMID:29420703 NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000 		JBrowse link
G Adgrg7 adhesion G protein-coupled receptor G7 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of ADGRG7 mRNA CTD PMID:33484791 NCBI chr11:43,808,101...43,877,539
Ensembl chr11:43,813,801...43,876,316 		JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide increases expression EXP Streptozocin results in increased expression of ADH1 mRNA CTD PMID:25905778 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions
decreases secretion
decreases expression		 EXP
ISO		 1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased secretion of ADIPOQ protein]]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased secretion of ADIPOQ protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of ADIPOQ protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of ADIPOQ protein; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ mRNA]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ mRNA]]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; geraniol promotes the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of ADIPOQ protein]; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of ADIPOQ protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of ADIPOQ protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of ADIPOQ protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; omaveloxolone analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]
Streptozocin results in decreased expression of ADIPOQ mRNA; Streptozocin results in decreased expression of ADIPOQ protein		 CTD PMID:17270171 PMID:21439372 PMID:21912612 PMID:22675305 PMID:24854284 More... NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adipor1 adiponectin receptor 1 decreases expression
increases expression
multiple interactions		 EXP Streptozocin results in decreased expression of ADIPOR1 protein
Streptozocin results in increased expression of ADIPOR1 protein
1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in increased expression of ADIPOR1 protein]]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in increased expression of ADIPOR1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of ADIPOR1 protein]		 CTD PMID:17270171 PMID:24413998 PMID:29274332 NCBI chr13:45,859,461...45,879,248
Ensembl chr13:45,859,533...45,879,241 		JBrowse link
G Adipor2 adiponectin receptor 2 multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]] CTD PMID:21912612 NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355 		JBrowse link
G Adora2a adenosine A2a receptor increases expression ISO Streptozocin results in increased expression of ADORA2A protein CTD PMID:26654777 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Adra1a adrenoceptor alpha 1A increases expression EXP Streptozocin results in increased expression of ADRA1A mRNA; Streptozocin results in increased expression of ADRA1A protein CTD PMID:19133277 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Adra1b adrenoceptor alpha 1B increases expression EXP Streptozocin results in increased expression of ADRA1B mRNA CTD PMID:19298542 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919 		JBrowse link
G Adra1d adrenoceptor alpha 1D decreases expression EXP Streptozocin results in decreased expression of ADRA1D mRNA CTD PMID:19298542 NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354 		JBrowse link
G Adrb1 adrenoceptor beta 1 multiple interactions
decreases expression		 EXP Metoprolol inhibits the reaction [Streptozocin results in decreased expression of ADRB1 protein] CTD PMID:18703049 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Adrb2 adrenoceptor beta 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ADRB2 protein
Metoprolol promotes the reaction [Streptozocin results in increased expression of ADRB2 protein]		 CTD PMID:18703049 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions
increases expression		 EXP Metoprolol promotes the reaction [Streptozocin results in increased expression of ADRB3 protein] CTD PMID:18703049 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552 		JBrowse link
G Afmid arylformamidase increases expression EXP Streptozocin results in increased expression of AFMID mRNA CTD PMID:25905778 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718 		JBrowse link
G Afp alpha-fetoprotein multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of AFP mRNA CTD PMID:29127188 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Ager advanced glycosylation end product-specific receptor increases expression
increases response to substance
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of AGER mRNA; Streptozocin results in increased expression of AGER protein
AGER protein results in increased susceptibility to Streptozocin
manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Streptozocin results in increased expression of AGER mRNA]
[Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; Kangen-karyu inhibits the reaction [Streptozocin results in increased expression of AGER protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of AGER protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of AGER protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of AGER mRNA]		 CTD PMID:19397970 PMID:19833897 PMID:22476978 PMID:25199697 PMID:27109771 More... NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Agrp agouti related neuropeptide multiple interactions
increases expression		 EXP INS protein inhibits the reaction [Streptozocin results in increased expression of AGRP mRNA] CTD PMID:20219977 NCBI chr19:33,447,992...33,481,602
Ensembl chr19:33,447,992...33,449,584 		JBrowse link
G Agt angiotensinogen multiple interactions
decreases abundance
increases expression		 ISO
EXP		 CEBPB protein affects the reaction [Streptozocin results in increased expression of AGT protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased abundance of AGT protein modified form]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of AGT protein]; Valsartan inhibits the reaction [Streptozocin results in decreased abundance of AGT protein modified form]; Valsartan promotes the reaction [Streptozocin results in increased expression of AGT protein]
Streptozocin results in increased expression of AGT mRNA; Streptozocin results in increased expression of AGT protein
Streptozocin results in increased expression of AGT mRNA; Streptozocin results in increased expression of AGT protein; Streptozocin results in increased expression of AGT protein modified form
ACE2 inhibits the reaction [Streptozocin results in increased expression of AGT protein modified form]; AGT protein modified form inhibits the reaction [Streptozocin results in decreased abundance of Cyclic GMP]; AGT protein modified form inhibits the reaction [Streptozocin results in increased expression of PDE5 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of AGT protein modified form]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of AGT protein]		 CTD PMID:11375343 PMID:15643138 PMID:17724226 PMID:18487452 PMID:20547220 More... NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions
increases expression		 ISO
EXP		 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of AGTR1A mRNA]; [Perindopril co-treated with AM6545] inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; [Streptozocin co-treated with Niacinamide] results in increased expression of AGTR1A mRNA; AM6545 inhibits the reaction [Streptozocin results in increased expression of AGTR1A mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of AGTR1A mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of AGTR1A mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; Valsartan promotes the reaction [Streptozocin results in increased expression of AGTR1 protein]
[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR1A mRNA; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR1A mRNA]
Streptozocin results in increased expression of AGTR1 protein; Streptozocin results in increased expression of AGTR1A mRNA; Streptozocin results in increased expression of AGTR1A protein		 CTD PMID:17724226 PMID:18487452 PMID:21381899 PMID:28946194 PMID:29266779 More... NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of AGTR2 mRNA; Streptozocin results in increased expression of AGTR2 protein
CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein]
[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR2 mRNA; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of AGTR2 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein]; esculetin promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR2 mRNA]		 CTD PMID:15587404 PMID:17724226 PMID:28946194 PMID:29266779 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 multiple interactions
decreases expression		 EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of AGXT2 protein] CTD PMID:19634143 NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926 		JBrowse link
G Ahcy adenosylhomocysteinase multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of AHCY mRNA; [Streptozocin co-treated with Dietary Fats] results in increased methylation of AHCY gene CTD PMID:29127188 NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393 		JBrowse link
G Ahr aryl hydrocarbon receptor decreases expression ISO Streptozocin results in decreased expression of AHR mRNA CTD PMID:22531820 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of AIFM1 protein
[Streptozocin co-treated with NQO1 protein mutant form] results in increased expression of AIFM1 protein; FGF21 protein affects the reaction [Streptozocin results in increased expression of AIFM1]
Trientine inhibits the reaction [Streptozocin results in increased expression of AIFM1 protein]		 CTD PMID:19634143 PMID:23458895 PMID:23499715 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Ajm1 apical junction component 1 homolog multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of AJM1 mRNA CTD PMID:33484791 NCBI chr 3:8,394,942...8,401,323
Ensembl chr 3:8,392,889...8,401,321 		JBrowse link
G Ak4 adenylate kinase 4 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of AK4 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of AK4 protein]		 CTD PMID:19634143 NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618 		JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of AKR1A1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of AKR1A1 protein]		 CTD PMID:19634143 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 multiple interactions ISO Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK1 protein]; Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK3 protein]; Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK8 protein]; Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK9 protein] CTD PMID:25541468 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 multiple interactions EXP
ISO		 [resveratrol co-treated with Streptozocin] results in decreased expression of AKR1C3 mRNA
[Streptozocin co-treated with Dietary Fats] results in increased expression of AKR1C18 mRNA		 CTD PMID:25905778 PMID:29127188 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP Streptozocin results in increased expression of AKR7A3 mRNA CTD PMID:25905778 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases expression
increases phosphorylation
decreases phosphorylation
decreases expression		 EXP
ISO		 [cobaltiprotoporphyrin co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein; [Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein; [Resveratrol co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with Niacinamide] results in decreased phosphorylation of AKT1 protein; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased phosphorylation of AKT1 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of AKT1 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of AKT1 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of AKT1 mRNA]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of AKT1 protein]; Propofol promotes the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased phosphorylation of AKT1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]; Streptozocin results in decreased expression of and results in decreased phosphorylation of AKT1 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; tin mesoporphyrin inhibits the reaction [[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein]; Tribulus extract inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]]
streptozocin increases phosphorylation of Akt1 protein in heart
[Dietary Fats co-treated with Streptozocin] results in decreased expression of AKT1 mRNA; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with CNR1 protein] affects the phosphorylation of AKT1 protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of AKT1 protein; Metformin inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein]
Streptozocin results in decreased expression of AKT1 mRNA; Streptozocin results in decreased expression of AKT1 protein		 CTD
RGD		 PMID:16595661 PMID:19002579 PMID:22675305 PMID:24810525 PMID:25541178 More... RGD:156430337 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT2 protein; Butyric Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT2 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT2 protein] CTD PMID:27270450 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Alad aminolevulinate dehydratase multiple interactions ISO [Streptozocin results in increased abundance of Blood Glucose] which results in decreased expression of ALAD protein; alpha-Tocopherol inhibits the reaction [[Streptozocin results in increased abundance of Blood Glucose] which results in decreased expression of ALAD protein] CTD PMID:7728901 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of ALAS1 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in decreased expression of ALAS1 mRNA]		 CTD PMID:16684804 NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917 		JBrowse link
G Alb albumin multiple interactions
increases expression
decreases expression
increases secretion		 ISO
EXP		 [Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in increased expression of ALB protein; AM6545 inhibits the reaction [Streptozocin results in increased expression of ALB protein]; naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in increased expression of ALB protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of ALB protein]; TXN protein inhibits the reaction [Streptozocin results in increased secretion of ALB protein]
Streptozocin results in decreased expression of ALB protein
[bisphenol A co-treated with Streptozocin] results in decreased expression of ALB protein; [Streptozocin co-treated with Cadmium] results in increased expression of ALB protein; [Streptozocin co-treated with Cholesterol, Dietary] results in increased secretion of ALB protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein; Curcumin inhibits the reaction [Streptozocin results in decreased expression of ALB protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of ALB protein]; Gallic Acid inhibits the reaction [Streptozocin results in decreased expression of ALB protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in increased secretion of ALB protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein]; LR-90 inhibits the reaction [Streptozocin results in increased expression of ALB protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of ALB protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of ALB protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of ALB protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein]		 CTD PMID:12845431 PMID:14871415 PMID:17360766 PMID:18204486 PMID:21450970 More... NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP Streptozocin results in increased expression of ALDH1A1 mRNA CTD PMID:25905778 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of ALDH1A3 mRNA CTD PMID:33484791 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member increases expression
multiple interactions
decreases expression		 EXP Streptozocin results in increased expression of ALDH2 protein
Ethanol inhibits the reaction [Streptozocin results in decreased expression of ALDH2]
Streptozocin results in decreased expression of ALDH2 mRNA; Streptozocin results in decreased expression of ALDH2 protein		 CTD PMID:21136691 PMID:23500772 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ALDOB protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ALDOB protein]		 CTD PMID:19634143 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116 		JBrowse link
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of ALKBH3 mRNA CTD PMID:20665664 NCBI chr 3:79,939,515...79,972,820
Ensembl chr 3:79,939,600...79,972,000 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ALOX5AP mRNA CTD PMID:29127188 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986 		JBrowse link
G Alpk1 alpha-kinase 1 multiple interactions
increases response to substance		 ISO [ALPK1 protein results in increased susceptibility to Streptozocin] which results in decreased expression of PRKG2 mRNA; [ALPK1 protein results in increased susceptibility to Streptozocin] which results in increased expression of TGFB1 mRNA; [ALPK1 protein results in increased susceptibility to Streptozocin] which results in increased expression of TGFB1 protein; ALPK1 protein promotes the reaction [Streptozocin results in decreased secretion of INS1 protein]; ALPK1 protein promotes the reaction [Streptozocin results in increased abundance of Blood Glucose] CTD PMID:27542954 NCBI chr 2:216,126,939...216,247,180
Ensembl chr 2:216,128,825...216,247,157 		JBrowse link
G Ambn ameloblastin multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of AMBN mRNA CTD PMID:33484791 NCBI chr14:19,601,761...19,614,382
Ensembl chr14:19,601,702...19,614,393 		JBrowse link
G Angpt1 angiopoietin 1 increases expression
multiple interactions
decreases expression		 EXP Streptozocin results in increased expression of ANGPT1 mRNA; Streptozocin results in increased expression of ANGPT1 protein
baicalin inhibits the reaction [Streptozocin results in decreased expression of ANGPT1 mRNA]		 CTD PMID:15643138 PMID:19958114 PMID:34414639 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Angpt2 angiopoietin 2 multiple interactions
increases expression		 EXP Enalapril inhibits the reaction [Streptozocin results in increased expression of ANGPT2 mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of ANGPT2 protein]
Streptozocin results in increased expression of ANGPT2 mRNA; Streptozocin results in increased expression of ANGPT2 protein		 CTD PMID:15643138 PMID:19958114 PMID:20821229 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804 		JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of ANGPTL4 mRNA CTD PMID:25905778 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ANKRD1 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of ANKRD1 mRNA]		 CTD PMID:16684804 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919 		JBrowse link
G Ankrd2 ankyrin repeat domain 2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of ANKRD2 mRNA CTD PMID:33484791 NCBI chr 1:240,847,111...240,856,563
Ensembl chr 1:240,847,072...240,856,566 		JBrowse link
G Anpep alanyl aminopeptidase, membrane decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of ANPEP protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ANPEP protein]		 CTD PMID:19634143 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789 		JBrowse link
G Anxa3 annexin A3 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ANXA3 protein
[resveratrol co-treated with Streptozocin] results in increased expression of ANXA3 mRNA; Trientine inhibits the reaction [Streptozocin results in increased expression of ANXA3 protein]		 CTD PMID:21136691 PMID:25905778 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617 		JBrowse link
G Anxa5 annexin A5 decreases expression
multiple interactions
increases expression		 EXP Streptozocin results in decreased expression of ANXA5 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ANXA5 protein]; Trientine inhibits the reaction [Streptozocin results in increased expression of ANXA5 protein]		 CTD PMID:19634143 PMID:21136691 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases response to substance ISO APEX1 protein mutant form results in increased susceptibility to Streptozocin CTD PMID:19470598 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions
increases expression		 EXP Trientine inhibits the reaction [Streptozocin results in increased expression of APOA1 protein] CTD PMID:19634143 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoa4 apolipoprotein A4 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of APOA4 mRNA CTD PMID:25905778 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Apob apolipoprotein B multiple interactions EXP [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of APOB mRNA CTD PMID:35786680 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Apoe apolipoprotein E increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of APOE mRNA
[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine]
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of APOE mRNA]		 CTD PMID:16380481 PMID:16684804 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G App amyloid beta precursor protein multiple interactions
increases expression		 EXP
ISO		 Memantine inhibits the reaction [Streptozocin results in increased expression of APP protein modified form]
5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of APP protein modified form]; Alendronate inhibits the reaction [Streptozocin results in increased expression of APP protein]; Donepezil inhibits the reaction [Streptozocin results in increased expression of APP protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of APP protein modified form]
Streptozocin results in increased expression of APP mRNA; Streptozocin results in increased expression of APP protein; Streptozocin results in increased expression of APP protein modified form		 CTD PMID:21069392 PMID:21290839 PMID:30481507 PMID:34428446 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Aqp1 aquaporin 1 multiple interactions
decreases expression		 EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of AQP1 protein] CTD PMID:19634143 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Aqp7 aquaporin 7 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of AQP7 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of AQP7 mRNA]		 CTD PMID:16684804 NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642 		JBrowse link
G Aqp9 aquaporin 9 increases expression EXP Streptozocin results in increased expression of AQP9 protein CTD PMID:22114114 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395 		JBrowse link
G Arg1 arginase 1 multiple interactions
increases activity
decreases expression
increases expression		 ISO
EXP		 [NTN1 protein co-treated with Streptozocin] results in increased expression of ARG1 protein; AM6545 inhibits the reaction [Streptozocin results in decreased expression of ARG1 mRNA]; ARG1 gene mutant form inhibits the reaction [Streptozocin results in increased expression of GLB1 protein]; Perindopril inhibits the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of ARG1 mRNA]]
Streptozocin results in increased activity of ARG1 protein
Streptozocin results in increased expression of ARG1 protein		 CTD PMID:29059224 PMID:29673160 PMID:30184259 PMID:34039237 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Arhgap9 Rho GTPase activating protein 9 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of ARHGAP9 mRNA CTD PMID:25905778 NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of ASNS mRNA CTD PMID:25905778 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Atf2 activating transcription factor 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ATF2 protein
resveratrol inhibits the reaction [Streptozocin results in increased expression of ATF2 protein]		 CTD PMID:26499206 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of ATF3 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of ATF3 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of ATF3 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of ATF3 protein CTD PMID:38282657 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases phosphorylation
increases expression		 ISO
EXP		 [Dietary Fats co-treated with Streptozocin] results in increased expression of ATF4 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF4 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of ATF4 protein]
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased phosphorylation of ATF4 protein]		 CTD PMID:24967692 PMID:30980806 PMID:33812996 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atf5 activating transcription factor 5 decreases expression EXP Streptozocin results in decreased expression of ATF5 mRNA CTD PMID:25905778 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707 		JBrowse link
G Atf6 activating transcription factor 6 increases cleavage
increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased cleavage of ATF6 protein
streptozocin increases expression of Atf6 protein in heart
[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF6 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF6 mRNA]
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased cleavage of ATF6 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein]		 CTD
RGD		 PMID:30980806 PMID:33812996 PMID:34801538 PMID:36044268 RGD:156430337 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atg12 autophagy related 12 increases expression ISO Streptozocin results in increased expression of ATG12 mRNA CTD PMID:24889822 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418 		JBrowse link
G Atg5 autophagy related 5 increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of ATG5 mRNA
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of ATG5 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of ATG5 mRNA		 CTD PMID:24889822 PMID:35786680 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Atox1 antioxidant 1 copper chaperone decreases expression EXP Streptozocin results in decreased expression of ATOX1 protein CTD PMID:24927960 NCBI chr10:39,564,855...39,579,892
Ensembl chr10:39,564,857...39,579,950 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 decreases activity
decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in decreased activity of ATP2A2 protein
Streptozocin results in decreased expression of ATP2A2 mRNA
[bisphenol A co-treated with Streptozocin] results in decreased expression of ATP2A2 mRNA; [Ethinyl Estradiol co-treated with Streptozocin] results in decreased expression of ATP2A2 mRNA; [octylphenol co-treated with Streptozocin] results in decreased expression of ATP2A2 mRNA		 CTD PMID:16685413 PMID:29935216 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101 		JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 multiple interactions ISO [Streptozocin co-treated with bisphenol A] results in decreased expression of ATP2A3 mRNA; [Streptozocin co-treated with octylphenol] results in decreased expression of ATP2A3 mRNA CTD PMID:29935216 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 multiple interactions
increases expression		 ISO [Streptozocin co-treated with bisphenol A] results in increased expression of ATP2B1 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of ATP2B1 mRNA
Streptozocin results in increased expression of ATP2B1 mRNA		 CTD PMID:29935216 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295 		JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ATP5F1A protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5F1A protein]		 CTD PMID:21136691 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794 		JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ATP5F1B protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5F1B protein]		 CTD PMID:21136691 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273 		JBrowse link
G Atp5mf ATP synthase membrane subunit f increases expression
affects expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of ATP5MF protein
Streptozocin affects the expression of ATP5MF mRNA
Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5MF protein]		 CTD PMID:18583417 PMID:19634143 NCBI chr12:9,421,665...9,428,236
Ensembl chr12:9,421,579...9,428,236 		JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ATP5PO protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5PO protein]		 CTD PMID:19634143 NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592 		JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 multiple interactions
increases expression		 EXP (3,4-dihydroxyphenylamino)-2-imidazoline inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 mRNA]; (3,4-dihydroxyphenylamino)-2-imidazoline inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 protein]
Streptozocin results in increased expression of ATP6AP2 mRNA; Streptozocin results in increased expression of ATP6AP2 protein		 CTD PMID:18192338 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918 		JBrowse link
G Atp7a ATPase copper transporting alpha multiple interactions
decreases expression		 ISO ATP7A gene mutant form promotes the reaction [Streptozocin results in increased chemical synthesis of Superoxides]; ATP7A protein inhibits the reaction [Streptozocin results in increased chemical synthesis of Superoxides]; INS protein inhibits the reaction [Streptozocin results in decreased expression of ATP7A protein] CTD PMID:23884884 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Atp7b ATPase copper transporting beta decreases expression EXP Streptozocin results in decreased expression of ATP7B protein CTD PMID:24927960 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636 		JBrowse link
G Avp arginine vasopressin multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of AVP mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of AVP mRNA] CTD PMID:32303808 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Axl Axl receptor tyrosine kinase increases expression EXP Streptozocin results in increased expression of AXL protein CTD PMID:12644472 NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265 		JBrowse link
G B2m beta-2 microglobulin increases expression
multiple interactions		 EXP Streptozocin results in increased expression of B2M protein
diphenyldiselenide inhibits the reaction [Streptozocin results in increased activity of B2M protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of B2M protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of B2M protein]		 CTD PMID:33639173 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766 		JBrowse link
G B3galnt1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of B3GALNT1 mRNA CTD PMID:25905778 NCBI chr 2:153,847,297...153,877,371
Ensembl chr 2:153,846,474...153,877,332 		JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of BAAT mRNA CTD PMID:29382564 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685 		JBrowse link
G Bace1 beta-secretase 1 multiple interactions
increases expression		 ISO Alendronate inhibits the reaction [Streptozocin results in increased expression of BACE1 protein]; Donepezil inhibits the reaction [Streptozocin results in increased expression of BACE1 protein] CTD PMID:30481507 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions
increases expression
decreases expression		 EXP Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BAD protein modified form]; Anthocyanins inhibits the reaction [Streptozocin results in increased expression of BAD protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of BAD protein]; Streptozocin results in increased phosphorylation of and results in decreased activity of BAD protein
Streptozocin results in decreased expression of BAD protein; Streptozocin results in decreased expression of BAD protein modified form		 CTD PMID:15976052 PMID:19682444 PMID:28856781 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases expression		 EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of BAK1 protein] CTD PMID:28856781 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
affects expression
increases expression		 ISO
EXP		 [Streptozocin co-treated with Dietary Fats] results in increased expression of BAX protein; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of BAX protein]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of BAX protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of BAX protein]
Streptozocin affects the expression of BAX protein
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in increased expression of BAX protein]]; 2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]; [Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein; Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Calcitriol inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Curcumin inhibits the reaction [Streptozocin affects the expression of BAX protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Diazoxide inhibits the reaction [Streptozocin results in increased expression of BAX protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of BAX protein]; ferulic acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Phycocyanin inhibits the reaction [Streptozocin results in increased expression of BAX protein]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of BAX]; Rivastigmine inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of BAX protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Testosterone inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Testosterone promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Testosterone promotes the reaction [Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]]; Testosterone promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Testosterone promotes the reaction [Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in increased expression of BAX protein]]; Zinc inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Zinc inhibits the reaction [Streptozocin results in increased expression of BAX protein]
Streptozocin results in increased expression of BAX; Streptozocin results in increased expression of BAX mRNA; Streptozocin results in increased expression of BAX protein		 CTD PMID:11375343 PMID:18758938 PMID:19931367 PMID:20574430 PMID:20650802 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B affects expression ISO Streptozocin affects the expression of BAZ1B mRNA CTD PMID:26073000 NCBI chr12:21,431,985...21,489,956
Ensembl chr12:21,431,985...21,490,426 		JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of BBOX1 mRNA CTD PMID:25905778 NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458 		JBrowse link
G Bche butyrylcholinesterase multiple interactions
increases activity		 ISO Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of BCHE protein] CTD PMID:27087133 PMID:30481507 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha affects expression ISO Streptozocin affects the expression of BCKDHA mRNA CTD PMID:18583417 NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
affects expression
multiple interactions
decreases expression		 EXP
ISO		 Streptozocin results in increased expression of BCL2 protein
Streptozocin affects the expression of BCL2 protein
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]]; 2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; [Streptozocin co-treated with Arsenic] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Cadmium] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein; [Streptozocin co-treated with Lead co-treated with Manganese co-treated with Cadmium co-treated with Arsenic] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Lead] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Manganese] results in decreased expression of BCL2 mRNA; Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Curcumin inhibits the reaction [Streptozocin affects the expression of BCL2 protein]; Diazoxide inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; fasudil inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of BCL2 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BCL2 mRNA]; Organoselenium Compounds inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Propofol inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of BCL2 protein]; Streptozocin promotes the reaction [IGF2R protein modified form results in decreased expression of BCL2 protein modified form]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Testosterone inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Testosterone promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Testosterone promotes the reaction [Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]]; Testosterone promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Testosterone promotes the reaction [Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]]; Zinc inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Zinc inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]
[Diethylhexyl Phthalate co-treated with Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 protein; [Streptozocin co-treated with arachidonyl-2-chloroethylamide] results in increased expression of BCL2 protein; [Streptozocin co-treated with bisphenol A] results in increased expression of BCL2 mRNA; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of BCL2 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of BCL2 mRNA; AM 251 inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; bisphenol A promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; Ethinyl Estradiol promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; montelukast inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; octylphenol promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; Streptozocin inhibits the reaction [Cisplatin results in increased expression of BCL2 protein]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]
Streptozocin results in decreased expression of BCL2 mRNA; Streptozocin results in decreased expression of BCL2 protein		 CTD PMID:15056984 PMID:15587404 PMID:15976052 PMID:16909474 PMID:18758938 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2a1 BCL2-related protein A1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of BCL2A1 mRNA CTD PMID:25905778 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of BCL2L1 protein
Streptozocin results in decreased expression of BCL2L1 mRNA
Streptozocin results in decreased expression of BCL2L1 mRNA; Streptozocin results in decreased expression of BCL2L1 protein
Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of BCL2L1 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of BCL2L1 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BCL2L1 mRNA]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]]		 CTD PMID:15976052 PMID:16595661 PMID:18758938 PMID:19682444 PMID:24781736 More... NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression
multiple interactions		 ISO Streptozocin results in increased expression of BCL2L11 mRNA
Chlorpyrifos promotes the reaction [Streptozocin results in increased expression of BCL2L11 mRNA]		 CTD PMID:33524429 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bcl3 BCL3, transcription coactivator multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of BCL3 mRNA CTD PMID:25905778 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607 		JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of BDH1 mRNA CTD PMID:25905778 NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671 		JBrowse link
G Bdkrb1 bradykinin receptor B1 increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of BDKRB1 mRNA
[HOE 140, desArg(10)- binds to and results in decreased activity of BDKRB1 protein] which results in decreased susceptibility to Streptozocin		 CTD PMID:17989505 PMID:19516248 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747 		JBrowse link
G Bdkrb2 bradykinin receptor B2 increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of BDKRB2 mRNA
[icatibant binds to and results in decreased activity of BDKRB2 protein] which results in decreased susceptibility to Streptozocin		 CTD PMID:17989505 PMID:19516248 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497 		JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in decreased expression of BDNF mRNA; Streptozocin results in decreased expression of BDNF protein
5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]
Metformin inhibits the reaction [Streptozocin results in increased expression of BDNF mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BDNF mRNA]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]]		 CTD PMID:32805344 PMID:34428446 PMID:35414346 PMID:38049026 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Becn1 beclin 1 increases expression
multiple interactions
decreases expression		 ISO
EXP		 Streptozocin results in increased expression of BECN1 mRNA; Streptozocin results in increased expression of BECN1 protein
[[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of BECN1 mRNA
Streptozocin results in decreased expression of BECN1 protein; Streptozocin results in decreased expression of BECN1 protein modified form
5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of BECN1 protein modified form]; HU 308 inhibits the reaction [Streptozocin results in decreased expression of BECN1 protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BECN1 protein modified form]		 CTD PMID:24889822 PMID:30459625 PMID:34428446 PMID:35786680 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in decreased expression of BGLAP mRNA; Streptozocin results in decreased expression of BGLAP protein
[Streptozocin co-treated with Dietary Fats] results in decreased expression of BGLAP protein; Calcitriol inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of BGLAP protein]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of BGLAP protein modified form; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of BGLAP protein modified form]		 CTD PMID:25617479 PMID:27488359 PMID:33450223 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase increases activity
multiple interactions
increases expression		 EXP
ISO		 Streptozocin results in increased activity of BHMT protein
[Streptozocin co-treated with Dietary Fats] affects the expression of BHMT mRNA
Streptozocin results in increased expression of BHMT mRNA		 CTD PMID:16835399 PMID:29127188 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of BMAL1 mRNA CTD PMID:29127188 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Bmp6 bone morphogenetic protein 6 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of BMP6 mRNA
esculetin inhibits the reaction [Streptozocin results in decreased expression of BMP6 mRNA]		 CTD PMID:21450970 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Bmp7 bone morphogenetic protein 7 increases expression
affects expression		 EXP Streptozocin results in increased expression of BMP7 protein
Streptozocin affects the expression of BMP7 mRNA		 CTD PMID:17437042 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G C1qa complement C1q A chain multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of C1QA mRNA CTD PMID:25905778 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534 		JBrowse link
G C1qb complement C1q B chain increases expression
multiple interactions		 EXP Streptozocin results in increased expression of C1QB mRNA
[resveratrol co-treated with Streptozocin] results in increased expression of C1QB mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of C1QB mRNA]		 CTD PMID:16684804 PMID:25905778 NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407 		JBrowse link
G C1qc complement C1q C chain multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of C1QC mRNA CTD PMID:25905778 NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017 		JBrowse link
G C4b complement C4B increases expression
multiple interactions		 EXP Streptozocin results in increased expression of C4B mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of C4B mRNA]		 CTD PMID:16684804 NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681 		JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CACNA1B mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CACNA1B mRNA] CTD PMID:33484791 NCBI chr 3:7,380,892...7,546,104
Ensembl chr 3:7,380,922...7,546,091 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C multiple interactions
increases expression		 ISO [bisphenol A co-treated with Streptozocin] results in decreased expression of CACNA1C mRNA; [octylphenol co-treated with Streptozocin] results in decreased expression of CACNA1C mRNA
Streptozocin results in increased expression of CACNA1C mRNA		 CTD PMID:29935216 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacna1s calcium voltage-gated channel subunit alpha1 S multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CACNA1S mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CACNA1S mRNA] CTD PMID:33484791 NCBI chr13:47,493,949...47,564,194
Ensembl chr13:47,493,949...47,564,318 		JBrowse link
G Calca calcitonin-related polypeptide alpha decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of CALCA protein
Botulinum Toxins, Type A inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]; capsazepine inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]; RN 1734 inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]; U 0126 inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]		 CTD PMID:30583000 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Calm1 calmodulin 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of CALM1 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of CALM1 protein] CTD PMID:32303808 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227 		JBrowse link
G Calm3 calmodulin 3 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of CALM3 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of CALM3 protein]		 CTD PMID:19634143 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207 		JBrowse link
G Calr calreticulin decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of CALR protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of CALR protein]		 CTD PMID:19634143 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions
decreases expression		 ISO
EXP		 myristoylated autocamtide-2-related inhibitory peptide inhibits the reaction [Streptozocin results in increased phosphorylation of CAMK2A protein]; resveratrol inhibits the reaction [Streptozocin results in increased expression of and results in increased phosphorylation of and results in increased activity of CAMK2A protein]; Streptozocin results in increased expression of and results in increased phosphorylation of and results in increased activity of CAMK2A protein
Streptozocin results in decreased expression of CAMK2A mRNA; Streptozocin results in decreased expression of CAMK2A protein
Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of CAMK2A mRNA]; Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of CAMK2A protein]; Memantine inhibits the reaction [Streptozocin results in decreased expression of CAMK2A mRNA]; Memantine inhibits the reaction [Streptozocin results in decreased expression of CAMK2A protein]		 CTD PMID:20424226 PMID:24333387 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Camp cathelicidin antimicrobial peptide multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CAMP mRNA CTD PMID:33484791 NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543 		JBrowse link
G Canx calnexin multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of CANX protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of CANX protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of CANX protein] CTD PMID:34801538 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821 		JBrowse link
G Capg capping actin protein, gelsolin like multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CAPG mRNA CTD PMID:25905778 NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856 		JBrowse link
G Capn8 calpain 8 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CAPN8 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CAPN8 mRNA] CTD PMID:33484791 NCBI chr13:94,252,218...94,316,146
Ensembl chr13:94,253,054...94,316,146 		JBrowse link
G Car3 carbonic anhydrase 3 multiple interactions
decreases expression		 EXP [resveratrol co-treated with Streptozocin] results in decreased expression of CAR3 mRNA
Streptozocin results in decreased expression of CAR3 mRNA		 CTD PMID:25905778 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Cartpt CART prepropeptide decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of CARTPT mRNA
GHRL protein promotes the reaction [Streptozocin results in decreased expression of CARTPT mRNA]		 CTD PMID:20219977 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Casp1 caspase 1 multiple interactions
increases expression		 EXP
ISO		 [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of CASP1 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; Ozone inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; palbinone inhibits the reaction [Streptozocin results in increased expression of and results in increased cleavage of CASP1 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of CASP1 protein]; scutellarin inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; Streptozocin results in increased expression of and results in increased cleavage of CASP1 protein
[aucubin co-treated with Streptozocin co-treated with Dietary Fats] results in decreased cleavage of CASP1 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of CASP1 protein; [Streptozocin co-treated with Dextran Sulfate] results in increased cleavage of CASP1 protein; [Streptozocin co-treated with Dietary Fats] results in increased activity of CASP1 protein; GSDMD protein affects the reaction [Streptozocin results in increased cleavage of CASP1 protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CASP1 protein]; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of CASP1 protein]; Streptozocin results in increased expression of and results in increased cleavage of CASP1 protein
Streptozocin results in increased expression of CASP1 mRNA; Streptozocin results in increased expression of CASP1 protein		 CTD PMID:23647015 PMID:26614261 PMID:27783111 PMID:32202043 PMID:34212273 More... NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp12 caspase 12 increases expression
multiple interactions
increases cleavage		 ISO
EXP		 Streptozocin results in increased expression of CASP12 protein modified form
Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein]
FGF21 protein affects the reaction [Streptozocin results in increased expression of CASP12 protein modified form]; sulforaphane inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein]		 CTD PMID:23499715 PMID:24967692 PMID:25541178 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression
increases expression
increases activity
increases cleavage
decreases cleavage		 EXP
ISO		 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; [Streptozocin co-treated with Arsenic] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Cadmium] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with IGF2R protein modified form] results in increased expression of CASP3 protein modified form; [Streptozocin co-treated with Lead co-treated with Manganese co-treated with Cadmium co-treated with Arsenic] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Lead] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Manganese] results in increased expression of CASP3 mRNA; Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Anthocyanins inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased cleavage of CASP3 protein]; ferulic acid analog inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Ibuprofen inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; Imatinib Mesylate inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]]; Memantine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; nifuroxazide inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Ozone inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of CASP3 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of CASP3 protein modified form]; Propofol inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Rivastigmine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Streptozocin results in increased expression of and results in increased cleavage of CASP3 protein; Thioctic Acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]
Streptozocin results in decreased expression of CASP3 mRNA; Streptozocin results in decreased expression of CASP3 protein
Streptozocin results in increased expression of CASP3 mRNA; Streptozocin results in increased expression of CASP3 protein modified form
Streptozocin results in increased expression of CASP3 mRNA; Streptozocin results in increased expression of CASP3 protein; Streptozocin results in increased expression of CASP3 protein modified form
[Streptozocin co-treated with bisphenol A] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] affects the cleavage of CASP3 protein; [Streptozocin co-treated with NQO1 protein mutant form] results in increased expression of CASP3 protein modified form; [Streptozocin co-treated with octylphenol] results in increased expression of CASP3 mRNA; fatostatin promotes the reaction [Streptozocin results in increased cleavage of CASP3 protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of CASP3 protein modified form]; NTN1 protein inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Quercetin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Streptozocin inhibits the reaction [Cisplatin results in increased expression of CASP3 protein]; Streptozocin inhibits the reaction [Ethinyl Estradiol results in decreased expression of CASP3 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]
Streptozocin analog results in increased activity of CASP3 protein; Streptozocin results in increased activity of CASP3 protein		 CTD PMID:12502508 PMID:15976052 PMID:18721751 PMID:18758938 PMID:19133311 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp4 caspase 4 increases expression ISO Streptozocin results in increased expression of CASP4 mRNA CTD PMID:34212273 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Casp6 caspase 6 increases expression EXP Streptozocin results in increased expression of CASP6 protein CTD PMID:15976052 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Casp7 caspase 7 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of CASP7 protein
[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]; Metformin promotes the reaction [dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]]		 CTD PMID:15976052 PMID:30551545 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity
increases cleavage
increases expression		 EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of CASP8 protein]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP8 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of CASP8 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CASP8 mRNA]; nifuroxazide inhibits the reaction [Streptozocin results in increased activity of CASP8 protein]
Streptozocin results in increased expression of CASP8 mRNA; Streptozocin results in increased expression of CASP8 protein		 CTD PMID:23267840 PMID:25541178 PMID:28856781 PMID:29606028 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 multiple interactions
decreases expression
increases activity
increases expression		 EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of CASP9 protein]; IGF2R protein modified form inhibits the reaction [Streptozocin results in increased expression of CASP9 protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of CASP9 mRNA]]; nifuroxazide inhibits the reaction [Streptozocin results in increased activity of CASP9 protein]; Ozone inhibits the reaction [Streptozocin results in increased expression of CASP9 mRNA]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of CASP9 protein]; Streptozocin results in increased expression of and results in increased cleavage of CASP9 protein; Thioctic Acid inhibits the reaction [Streptozocin results in increased expression of CASP9 protein]
Streptozocin results in increased expression of CASP9 mRNA; Streptozocin results in increased expression of CASP9 protein		 CTD PMID:15976052 PMID:19951573 PMID:22940631 PMID:26614261 PMID:28856781 More... NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase increases expression
decreases activity
increases activity
multiple interactions
decreases expression
increases phosphorylation
decreases response to substance		 ISO
EXP		 Streptozocin results in increased expression of CAT mRNA
Streptozocin results in decreased activity of CAT protein
Streptozocin results in increased activity of CAT protein
1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in increased expression of CAT protein]]; 2-hydroxy-4-methoxy benzoic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in increased expression of CAT protein]; 4-methyl-2-((2-methylbenzyl) amino)-1,3-thiazole-5-carboxylic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; 5,3'-dihydroxy-3,6,7,4',5'-pentamethoxyflavone inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CAT protein; [Fructose co-treated with Streptozocin] results in decreased activity of CAT protein; [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; [Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein; [Phytic Acid co-treated with Inositol] inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; [pimagedine co-treated with Fatty Acids, Omega-3] inhibits the reaction [Streptozocin results in increased activity of CAT protein]; [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in increased activity of CAT protein; [Propolis co-treated with Streptozocin] results in increased activity of CAT protein; [Quercetin co-treated with coenzyme Q10] inhibits the reaction [Streptozocin results in increased activity of CAT protein]; [Quercetin co-treated with Streptozocin] results in increased activity of CAT protein; [Rosiglitazone co-treated with Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Streptozocin co-treated with bisphenol A] results in decreased expression of CAT protein; [Streptozocin co-treated with Chlorpyrifos] results in increased activity of CAT protein; [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the activity of CAT protein; [Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein; [Streptozocin co-treated with Isoproterenol] affects the activity of CAT protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of CAT protein; [Zinc Sulfate results in increased abundance of Zinc] inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; allyl methyl sulfide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the activity of CAT protein]; Bezafibrate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; caryophyllene inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNA11 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNAQ protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of PLCB1 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of PLCB2 protein]; Chlorpyrifos promotes the reaction [Streptozocin results in increased activity of CAT protein]; Chromium inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; chromium tripicolinate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; corilagin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; coumarin inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein]; crocin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Diltiazem inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Diosmin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of CAT protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Gallic Acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; geraniol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Glyburide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Imatinib Mesylate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Imipramine inhibits the reaction [Streptozocin results in increased activity of CAT protein]; INS1 protein inhibits the reaction [Streptozocin results in increased activity of CAT protein]; isoquercitrin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Losartan inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; mangiferin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Melatonin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Metformin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased activity of CAT protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Metformin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; morin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; myrsinoic acid B inhibits the reaction [Streptozocin results in increased activity of CAT protein]; myrtenol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; naringenin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; palbinone inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; pinitol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in increased activity of CAT protein]; Propolis inhibits the reaction [Streptozocin results in increased activity of CAT protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of CAT protein]; Quercetin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Quercetin inhibits the reaction [Streptozocin results in increased activity of CAT protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of and results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; Resveratrol promotes the reaction [Streptozocin results in decreased expression of CAT mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the activity of CAT protein]; S-allylcysteine inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Saponins inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; sodium arsenate promotes the reaction [Streptozocin results in decreased activity of CAT protein]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Streptozocin inhibits the reaction [Lipopolysaccharides results in increased expression of CAT protein]; Streptozocin inhibits the reaction [Streptozocin results in increased expression of CAT protein]; Streptozocin promotes the reaction [Chlorpyrifos results in increased activity of CAT protein]; Streptozocin results in decreased expression of and results in decreased activity of CAT protein; Streptozocin results in increased expression of and results in increased activity of CAT protein; thymoquinone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Tocotrienols inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; U 78517F inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; vanillin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased activity of CAT protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Zinc inhibits the reaction [Streptozocin results in decreased activity of CAT protein]
Streptozocin results in decreased expression of CAT mRNA; Streptozocin results in decreased expression of CAT protein
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CAT mRNA; [Streptozocin co-treated with Dextran Sulfate] results in decreased expression of CAT protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein; [Streptozocin co-treated with INS1 protein co-treated with Glutathione] affects the expression of CAT mRNA; [Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein; Acrylamide promotes the reaction [Streptozocin results in decreased activity of CAT protein]; Alendronate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Donepezil inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; pterostilbene inhibits the reaction [Streptozocin results in decreased expression of CAT]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; rhodioloside inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of CAT protein]
Streptozocin results in decreased expression of CAT; Streptozocin results in decreased expression of CAT mRNA
Streptozocin results in increased phosphorylation of CAT protein
CAT protein results in decreased susceptibility to Streptozocin
CAT protein promotes the reaction [SOD2 protein results in decreased susceptibility to Streptozocin]; SOD2 protein promotes the reaction [CAT protein results in decreased susceptibility to Streptozocin]		 CTD PMID:9522273 PMID:11424224 PMID:12123627 PMID:12242689 PMID:15298345 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cav1 caveolin 1 multiple interactions
increases expression		 EXP resveratrol inhibits the reaction [Streptozocin promotes the reaction [CAV1 protein binds to NOS3 protein]]; resveratrol inhibits the reaction [Streptozocin results in increased expression of CAV1 protein]; Streptozocin promotes the reaction [CAV1 protein binds to NOS3 protein] CTD PMID:18266981 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cav3 caveolin 3 multiple interactions
decreases expression		 EXP resveratrol inhibits the reaction [Streptozocin inhibits the reaction [CAV3 protein binds to SLC2A4 protein]]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of CAV3 protein]; Streptozocin inhibits the reaction [CAV3 protein binds to SLC2A4 protein] CTD PMID:18266981 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Cbr1 carbonyl reductase 1 decreases activity EXP Streptozocin results in decreased activity of CBR1 protein CTD PMID:11057757 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
G Cbs cystathionine beta synthase multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of CBS mRNA CTD PMID:29127188 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 affects response to substance
increases secretion
multiple interactions
increases expression		 ISO
EXP		 CCL2 affects the susceptibility to Streptozocin
Streptozocin results in increased secretion of CCL2 protein
4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]; [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 protein; [fatostatin co-treated with Streptozocin] results in increased expression of CCL2 protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of CCL2 protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of CCL2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 mRNA]; stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]]; Valsartan inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]
[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Flavonoids inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of CCL2 protein]; Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; PD 123319 inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; prolinedithiocarbamate inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Streptozocin results in increased expression of and results in increased secretion of CCL2 protein; Valsartan inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]
Streptozocin results in increased expression of CCL2 mRNA; Streptozocin results in increased expression of CCL2 protein
Streptozocin results in increased expression of CCL2; Streptozocin results in increased expression of CCL2 mRNA; Streptozocin results in increased expression of CCL2 protein		 CTD PMID:15284299 PMID:16374426 PMID:16684804 PMID:17624267 PMID:18413206 More... NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression
multiple interactions		 ISO Streptozocin results in increased expression of CCL3 mRNA
AM6545 inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]]		 CTD PMID:30184259 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO Streptozocin results in increased expression of CCL5 mRNA CTD PMID:29420703 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccl9 C-C motif chemokine ligand 9 multiple interactions EXP [Resveratrol co-treated with Streptozocin] results in increased expression of CCL6 mRNA CTD PMID:25905778 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369 		JBrowse link
G Ccn2 cellular communication network factor 2 increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of CCN2; Streptozocin results in increased expression of CCN2 protein
Streptozocin results in increased expression of CCN2 mRNA; Streptozocin results in increased expression of CCN2 protein
[Dietary Fats co-treated with Streptozocin] promotes the reaction [KLF15 gene mutant form results in increased expression of CCN2 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of CCN2 protein; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CCN2 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]
[Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in decreased expression of CCN2 protein; Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of CCN2 mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of CCN2 mRNA]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; idebenone inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; XLF-III-43 inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]		 CTD PMID:10026205 PMID:14586741 PMID:17270171 PMID:19369054 PMID:19657322 More... NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions		 ISO Streptozocin results in decreased expression of CCND1 mRNA
5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of CCND1 mRNA]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of CCND1 mRNA]		 CTD PMID:34428446 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd2 cyclin D2 decreases expression
multiple interactions		 ISO Streptozocin results in decreased expression of CCND2 protein
AM 251 inhibits the reaction [Streptozocin results in decreased expression of CCND2 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of CCND2 protein]		 CTD PMID:26967640 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Ccnt1 cyclin T1 multiple interactions EXP [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA; [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein] CTD PMID:20828602 NCBI chr 7:129,687,146...129,718,080
Ensembl chr 7:129,691,209...129,717,871 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression
multiple interactions		 ISO Streptozocin results in increased expression of CCR2 mRNA
[AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCR2 mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of CCR2 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of CCR2 mRNA]		 CTD PMID:30184259 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Ccs copper chaperone for superoxide dismutase decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of CCS mRNA; Streptozocin results in decreased expression of CCS protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of CCS mRNA]; Trientine inhibits the reaction [Streptozocin results in decreased expression of CCS protein]		 CTD PMID:24927960 NCBI chr 1:202,113,792...202,134,931
Ensembl chr 1:202,113,804...202,134,915 		JBrowse link
G Cd14 CD14 molecule multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CD14 mRNA CTD PMID:29127188 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Cd163 CD163 molecule multiple interactions
decreases expression		 EXP
ISO		 [resveratrol co-treated with Streptozocin] results in increased expression of CD163 mRNA
AM6545 inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]]		 CTD PMID:25905778 PMID:30184259 NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878 		JBrowse link
G Cd200r1l CD200 receptor 1-like multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CD200R1L mRNA CTD PMID:25905778 NCBI chr11:55,842,632...55,860,914
Ensembl chr11:55,842,634...55,885,680 		JBrowse link
G Cd24 CD24 molecule multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CD24A mRNA CTD PMID:29127188 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Cd36 CD36 molecule multiple interactions
increases expression		 ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CD36 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of CD36 mRNA] CTD PMID:29127188 PMID:34896238 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd53 Cd53 molecule multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CD53 mRNA CTD PMID:25905778 NCBI chr 2:194,352,139...194,399,668
Ensembl chr 2:194,352,139...194,399,657 		JBrowse link
G Cd5l Cd5 molecule-like multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CD5L mRNA CTD PMID:25905778 NCBI chr 2:172,791,007...172,802,018
Ensembl chr 2:172,790,934...172,829,753 		JBrowse link
G Cd68 Cd68 molecule multiple interactions
increases expression		 EXP
ISO		 [resveratrol co-treated with Streptozocin] results in increased expression of CD68 mRNA; nifuroxazide inhibits the reaction [Streptozocin results in increased expression of CD68 protein]
AM6545 inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]]		 CTD PMID:25905778 PMID:29291386 PMID:30184259 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697 		JBrowse link
G Cd80 Cd80 molecule multiple interactions
increases expression		 ISO Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of CD80 protein] CTD PMID:15892581 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030 		JBrowse link
G Cd86 CD86 molecule multiple interactions
increases expression		 ISO
EXP		 Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of CD86 protein]
[resveratrol co-treated with Streptozocin] results in increased expression of CD86 mRNA		 CTD PMID:15892581 PMID:25905778 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cdca2 cell division cycle associated 2 multiple interactions ISO [Diethylhexyl Phthalate co-treated with Streptozocin co-treated with Dietary Fats] results in increased expression of CDCA2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CDCA2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CDCA2 mRNA] CTD PMID:33484791 NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611 		JBrowse link
G Cdh1 cadherin 1 decreases expression EXP Streptozocin results in decreased expression of CDH1 CTD PMID:32469605 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh2 cadherin 2 decreases expression
multiple interactions		 ISO Streptozocin results in decreased expression of CDH2 protein
rhodioloside inhibits the reaction [Streptozocin results in decreased expression of CDH2 protein]		 CTD PMID:31682803 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdk15 cyclin-dependent kinase 15 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CDK15 mRNA CTD PMID:33484791 NCBI chr 9:60,710,787...60,803,638
Ensembl chr 9:60,711,715...60,802,777 		JBrowse link
G Cdk9 cyclin-dependent kinase 9 multiple interactions
increases phosphorylation		 EXP
ISO		 [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA; [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein]
Streptozocin results in increased phosphorylation of CDK9 protein		 CTD PMID:20828602 PMID:33631230 NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression		 ISO
EXP		 2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of CDKN1A mRNA]; [Streptozocin co-treated with Dietary Fats] results in increased expression of CDKN1A mRNA; Quercetin inhibits the reaction [Streptozocin results in increased expression of CDKN1A mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN1A]
Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of CDKN1A protein]; Streptozocin promotes the reaction [SETD7 protein binds to CDKN1A promoter]
Streptozocin results in increased expression of CDKN1A mRNA; Streptozocin results in increased expression of CDKN1A protein
Streptozocin results in increased expression of CDKN1A; Streptozocin results in increased expression of CDKN1A mRNA		 CTD PMID:19496084 PMID:22744176 PMID:25301743 PMID:27652271 PMID:29127188 More... NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression
multiple interactions		 ISO Streptozocin results in increased expression of CDKN2A mRNA; Streptozocin results in increased expression of CDKN2A protein
2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of CDKN2A mRNA]; 2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of CDKN2A protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN2A mRNA]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN2A protein]		 CTD PMID:29059224 PMID:29673160 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions
decreases expression		 ISO CEBPB protein affects the reaction [Streptozocin results in increased expression of AGT protein]; CEBPB protein affects the reaction [Streptozocin results in increased expression of TGFB1 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased abundance of AGT protein modified form]; CEBPB protein inhibits the reaction [Streptozocin results in decreased abundance of angiotensin I (1-7)]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of MAS1 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of MMP2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of ACE protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR1 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of IL6 protein]
Streptozocin results in decreased expression of CEBPB protein		 CTD PMID:29266779 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CEBPD mRNA CTD PMID:25905778 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829 		JBrowse link
G Celf2 CUGBP, Elav-like family member 2 multiple interactions ISO [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CELF2 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CELF2 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CELF2 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CELF2 protein CTD PMID:38282657 NCBI chr17:70,904,462...71,729,072
Ensembl chr17:71,210,853...71,728,333 		JBrowse link
G Celf4 CUGBP, Elav-like family member 4 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of CELF4 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CELF4 mRNA] CTD PMID:33484791 NCBI chr18:16,786,578...17,065,045
Ensembl chr18:16,786,867...17,064,786 		JBrowse link
G Ces2c carboxylesterase 2C multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CES2C mRNA CTD PMID:25905778 NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790 		JBrowse link
G Ces4a carboxylesterase 4A multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CES4A mRNA CTD PMID:33484791 NCBI chr19:33,011,731...33,030,119
Ensembl chr19:33,011,731...33,029,545 		JBrowse link
G Cfap45 cilia and flagella associated protein 45 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CFAP45 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CFAP45 mRNA] CTD PMID:33484791 NCBI chr13:84,989,474...85,012,880
Ensembl chr13:84,981,728...85,012,878 		JBrowse link
G Cfap69 cilia and flagella associated protein 69 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of CFAP69 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CFAP69 mRNA] CTD PMID:33484791 NCBI chr 4:28,379,604...28,452,562
Ensembl chr 4:28,375,996...28,450,698 		JBrowse link
G Cfd complement factor D increases expression EXP Streptozocin results in increased expression of CFD mRNA CTD PMID:3299706 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053 		JBrowse link
G Cfl1 cofilin 1 multiple interactions
increases phosphorylation		 EXP fasudil inhibits the reaction [Streptozocin results in increased phosphorylation of CFL1 protein] CTD PMID:22062134 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Cfp complement factor properdin multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CFP mRNA CTD PMID:25905778 NCBI chr  X:1,162,014...1,167,576
Ensembl chr  X:1,161,979...1,167,573 		JBrowse link
G Chat choline O-acetyltransferase multiple interactions
decreases expression
affects localization		 EXP Inositol inhibits the reaction [Streptozocin affects the localization of CHAT protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of CHAT protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of CHAT protein] CTD PMID:2431858 PMID:32805344 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093 		JBrowse link
G Chga chromogranin A multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CHGA mRNA CTD PMID:33484791 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398 		JBrowse link
G Chka choline kinase alpha multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CHKA mRNA CTD PMID:29127188 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions
increases expression
affects expression		 EXP 1-hexacosanol inhibits the reaction [Streptozocin affects the expression of CHRM2 mRNA]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 mRNA]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 protein]
Streptozocin results in increased expression of CHRM2 mRNA; Streptozocin results in increased expression of CHRM2 protein		 CTD PMID:17989502 PMID:18715473 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 multiple interactions
affects expression		 EXP 1-hexacosanol inhibits the reaction [Streptozocin affects the expression of CHRM3 mRNA] CTD PMID:17989502 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of CHRNA4 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CHRNA4 mRNA] CTD PMID:33484791 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Chst8 carbohydrate sulfotransferase 8 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of CHST8 mRNA CTD PMID:33484791 NCBI chr 1:87,294,144...87,435,900
Ensembl chr 1:87,294,540...87,435,900 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions
increases expression		 EXP Quercetin inhibits the reaction [Streptozocin results in increased expression of CHUK protein] CTD PMID:16177186 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Cidea cell death-inducing DFFA-like effector a multiple interactions EXP
ISO		 [resveratrol co-treated with Streptozocin] results in increased expression of CIDEA mRNA
[Streptozocin co-treated with Dietary Fats] results in increased expression of CIDEA mRNA		 CTD PMID:25905778 PMID:29127188 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481 		JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of CISD1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of CISD1 protein]		 CTD PMID:19634143 NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 increases expression
decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of CITED2 mRNA
Streptozocin results in decreased expression of CITED2 mRNA
SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of CITED2 mRNA]
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CITED2 mRNA]		 CTD PMID:16684804 PMID:27629361 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 multiple interactions
decreases expression		 EXP vanadyl sulfate inhibits the reaction [Streptozocin results in decreased expression of CKMT2 mRNA] CTD PMID:16684804 NCBI chr 2:23,079,918...23,110,518
Ensembl chr 2:23,079,918...23,110,430 		JBrowse link
G Cldn1 claudin 1 decreases expression EXP Streptozocin results in decreased expression of CLDN1 mRNA CTD PMID:25905778 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724 		JBrowse link
G Cldn11 claudin 11 decreases expression
multiple interactions		 ISO Streptozocin results in decreased expression of CLDN11 protein
rhodioloside inhibits the reaction [Streptozocin results in decreased expression of CLDN11 protein]		 CTD PMID:31682803 NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050 		JBrowse link
G Cldn2 claudin 2 decreases expression EXP Streptozocin results in decreased expression of CLDN2 mRNA CTD PMID:25905778 NCBI chr  X:103,459,870...103,473,794
Ensembl chr  X:103,459,780...103,474,838 		JBrowse link
G Clec4d C-type lectin domain family 4, member D multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CLEC4D mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CLEC4D mRNA] CTD PMID:33484791 NCBI chr 4:156,589,591...156,599,279
Ensembl chr 4:156,589,792...156,598,848 		JBrowse link
G Clec4f C-type lectin domain family 4, member F multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CLEC4F mRNA CTD PMID:25905778 NCBI chr 4:116,129,023...116,138,744
Ensembl chr 4:116,129,023...116,138,775 		JBrowse link
G Clic4 chloride intracellular channel 4 affects expression ISO Streptozocin affects the expression of CLIC4 mRNA CTD PMID:18583417 NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452 		JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit affects expression ISO Streptozocin affects the expression of CLPP mRNA CTD PMID:18583417 NCBI chr 9:1,831,680...1,837,700
Ensembl chr 9:1,830,311...1,837,693 		JBrowse link
G Clu clusterin increases expression
multiple interactions		 EXP Streptozocin results in increased expression of CLU protein
Trientine inhibits the reaction [Streptozocin results in increased expression of CLU protein]		 CTD PMID:19634143 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cnpy1 canopy FGF signaling regulator 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CNPY1 mRNA CTD PMID:33484791 NCBI chr 4:7,182,311...7,191,408
Ensembl chr 4:7,136,533...7,189,761 		JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
decreases expression
increases expression		 EXP
ISO		 [Fructose co-treated with Streptozocin] results in decreased expression of CNR1 mRNA; Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased expression of CNR1 mRNA]
Streptozocin results in decreased expression of CNR1 protein
[Streptozocin co-treated with CNR1 protein] affects the expression of IGF1R protein; [Streptozocin co-treated with CNR1 protein] affects the phosphorylation of AKT1 protein; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of CCND2 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of INS1 protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of CNR1 mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of CNR1 protein]
Streptozocin results in increased expression of CNR1 mRNA; Streptozocin results in increased expression of CNR1 protein		 CTD PMID:26967640 PMID:30184259 PMID:30642005 PMID:30721768 PMID:31468622 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression		 ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of COL1A1 mRNA; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of COL1A1 mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of COL1A1 mRNA] CTD PMID:28700904 PMID:29988851 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions
increases expression		 EXP
ISO		 INS1 protein inhibits the reaction [Streptozocin results in increased expression of COL3A1 protein]
Valsartan inhibits the reaction [Streptozocin results in increased expression of COL3A1 protein]		 CTD PMID:29266779 PMID:29682576 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression
multiple interactions
increases expression		 ISO
EXP		 Streptozocin results in decreased expression of COL4A1 mRNA
[fatostatin co-treated with Streptozocin] results in increased expression of COL4A1 mRNA
Streptozocin results in increased expression of COL4A1 mRNA
benazepril inhibits the reaction [Streptozocin results in increased expression of COL4A1 mRNA]; MFN2 protein mutant form inhibits the reaction [Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter]]; MFN2 protein mutant form inhibits the reaction [Streptozocin results in increased expression of COL4A1 mRNA]; Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter]		 CTD PMID:11798618 PMID:15496156 PMID:17582205 PMID:27997345 PMID:29420703 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412 		JBrowse link
G Col4a2 collagen type IV alpha 2 chain increases expression
multiple interactions		 ISO Streptozocin results in increased expression of COL4A2 mRNA
MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of COL4A2 mRNA]		 CTD PMID:30642005 NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839 		JBrowse link
G Col4a3 collagen type IV alpha 3 chain multiple interactions
increases expression		 EXP Zinc inhibits the reaction [Streptozocin results in increased expression of COL4A3 mRNA] CTD PMID:31009641 NCBI chr 9:83,875,849...84,004,955
Ensembl chr 9:83,875,561...84,001,895 		JBrowse link
G Col4a4 collagen type IV alpha 4 chain multiple interactions
increases expression		 ISO 3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased expression of COL4A4 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of COL4A4 mRNA] CTD PMID:33631230 NCBI chr 9:83,833,173...83,875,436
Ensembl chr 9:83,755,515...83,875,876 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain increases expression
multiple interactions		 EXP Streptozocin results in increased expression of COL6A1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of COL6A1 protein]		 CTD PMID:19634143 NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597 		JBrowse link
G Col6a2 collagen type VI alpha 2 chain increases expression
multiple interactions		 EXP Streptozocin results in increased expression of COL6A2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of COL6A2 protein]		 CTD PMID:19634143 NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564 		JBrowse link
G Col6a3 collagen type VI alpha 3 chain increases expression
multiple interactions		 EXP Streptozocin results in increased expression of COL6A3 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of COL6A3 protein]		 CTD PMID:19634143 NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471 		JBrowse link
G Col7a1 collagen type VII alpha 1 chain multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of COL7A1 mRNA CTD PMID:33484791 NCBI chr 8:109,604,877...109,637,249
Ensembl chr 8:109,604,861...109,637,252 		JBrowse link
G Cotl1 coactosin-like F-actin binding protein 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of COTL1 mRNA CTD PMID:25905778 NCBI chr19:47,871,689...47,906,010
Ensembl chr19:47,871,694...47,911,689 		JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 affects expression ISO Streptozocin affects the expression of COX17 mRNA CTD PMID:18583417 NCBI chr11:62,400,733...62,406,507 JBrowse link
G Cox5b cytochrome c oxidase subunit 5B multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of COX5B mRNA; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of COX5B mRNA] CTD PMID:37337224 NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052 		JBrowse link
G Cp ceruloplasmin multiple interactions
decreases expression		 EXP caryophyllene inhibits the reaction [Streptozocin results in decreased expression of CP protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of CP protein] CTD PMID:26748309 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Cpeb2 cytoplasmic polyadenylation element binding protein 2 multiple interactions ISO [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CPEB2 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CPEB2 protein] CTD PMID:38282657 NCBI chr14:67,787,503...67,839,973
Ensembl chr14:67,787,507...67,840,743 		JBrowse link
G Cpeb4 cytoplasmic polyadenylation element binding protein 4 multiple interactions ISO [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CPEB4 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CPEB4 protein CTD PMID:38282657 NCBI chr10:15,717,794...15,780,482
Ensembl chr10:15,717,794...15,780,603 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of CPT1A mRNA
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CPT1A mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of CPT1A mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CPT1A mRNA]
[resveratrol co-treated with Streptozocin] results in decreased expression of CPT1A mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CPT1A mRNA]		 CTD PMID:16684804 PMID:25905778 PMID:29988851 PMID:34896238 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of CPT2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of CPT2 protein]		 CTD PMID:21136691 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
decreases phosphorylation		 EXP
ISO		 [Streptozocin co-treated with Dietary Fats] results in decreased expression of CREB1 mRNA; Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of CREB1 protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased phosphorylation of CREB1 protein]
[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein; CREB1 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein]; MIR10A mRNA affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein]		 CTD PMID:20665664 PMID:23562514 PMID:27292126 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crebbp CREB binding protein decreases expression EXP Streptozocin results in decreased expression of CREBBP mRNA CTD PMID:25905778 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Crot carnitine O-octanoyltransferase decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of CROT mRNA
[resveratrol co-treated with Streptozocin] results in decreased expression of CROT mRNA		 CTD PMID:25905778 NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109 		JBrowse link
G Crp C-reactive protein multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CRP protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CRP protein] CTD PMID:33484791 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 increases expression EXP Streptozocin results in increased expression of CRY1 mRNA CTD PMID:25905778 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091 		JBrowse link
G Crybb3 crystallin, beta B3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CRYBB3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CRYBB3 mRNA] CTD PMID:33484791 NCBI chr12:43,557,103...43,562,120
Ensembl chr12:43,557,103...43,562,120 		JBrowse link
G Cryz crystallin zeta decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of CRYZ protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of CRYZ protein]		 CTD PMID:19634143 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758 		JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CSF1R mRNA CTD PMID:25905778 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Csrp3 cysteine and glycine rich protein 3 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of CSRP3 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CSRP3 mRNA]		 CTD PMID:16684804 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653 		JBrowse link
G Cst3 cystatin C multiple interactions
increases expression		 EXP [Streptozocin co-treated with Fructose] results in increased expression of CST3 protein; Glyburide inhibits the reaction [Streptozocin results in increased expression of CST3 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CST3 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of CST3 protein] CTD PMID:30551545 PMID:33387473 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822 		JBrowse link
G Cth cystathionine gamma-lyase multiple interactions ISO [Streptozocin co-treated with Dietary Fats] affects the expression of CTH mRNA CTD PMID:29127188 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
increases phosphorylation		 ISO 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased phosphorylation of CTNNB1 protein]; Tadalafil inhibits the reaction [Streptozocin results in increased phosphorylation of CTNNB1 protein] CTD PMID:34428446 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ctsd cathepsin D increases expression ISO Streptozocin results in increased expression of CTSD protein CTD PMID:28468961 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Ctsk cathepsin K increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of CTSK mRNA; Streptozocin results in increased expression of CTSK protein
formononetin inhibits the reaction [Streptozocin results in increased expression of CTSK mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of CTSK protein]		 CTD PMID:25617479 PMID:35315182 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Ctss cathepsin S increases expression
multiple interactions		 EXP Streptozocin results in increased expression of CTSS mRNA
[resveratrol co-treated with Streptozocin] results in increased expression of CTSS mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CTSS mRNA]		 CTD PMID:16684804 PMID:25905778 NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483 		JBrowse link
G Cubn cubilin multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of CUBN protein; bicalutamide promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CUBN protein] CTD PMID:35151640 NCBI chr17:76,385,046...76,593,133
Ensembl chr17:76,385,060...76,593,231 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of CXCL1 protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of CXCL1 protein]] CTD PMID:36547818 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions
decreases expression		 ISO [Streptozocin co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of KLF15 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[Streptozocin co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA]
Streptozocin results in decreased expression of CXCL12 mRNA; Streptozocin results in decreased expression of CXCL12 protein		 CTD PMID:18227068 PMID:34310909 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions EXP [Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of CXCR4 protein CTD PMID:30421503 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cyb561 cytochrome b-561 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CYB561 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CYB561 mRNA] CTD PMID:33484791 NCBI chr10:90,878,052...90,888,734
Ensembl chr10:90,878,054...90,884,787 		JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions
increases expression		 EXP [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of CYBA mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in increased expression of CYBA protein; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of CYBA mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of CYBA protein; [Resveratrol co-treated with Streptozocin] results in increased expression of CYBA mRNA; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of CYBA mRNA]; candesartan inhibits the reaction [Streptozocin results in increased expression of CYBA mRNA] CTD PMID:12967931 PMID:16139267 PMID:25905778 PMID:35786680 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Cybb cytochrome b-245 beta chain increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of CYBB mRNA; Streptozocin results in increased expression of CYBB protein
[Streptozocin co-treated with Dietary Fats] results in increased expression of CYBB protein; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CYBB protein]
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NOX2 mRNA]; [fatostatin co-treated with Streptozocin] results in increased expression of CYBB mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of NOX2 mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NOX2 mRNA]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of CYBB protein]		 CTD PMID:19957251 PMID:21381899 PMID:29420703 PMID:35085591 PMID:37120126 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Cyc1 cytochrome c-1 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of CYC1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of CYC1 protein]		 CTD PMID:19634143 NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479 		JBrowse link
G Cycs cytochrome c, somatic affects localization
increases expression
multiple interactions		 EXP Streptozocin affects the localization of CYCS protein
Streptozocin results in increased expression of CYCS mRNA; Streptozocin results in increased expression of CYCS protein
arjunolic acid inhibits the reaction [Streptozocin affects the localization of CYCS protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of CYCS mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of CYCS mRNA]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of CYCS protein]; Thioctic Acid inhibits the reaction [Streptozocin affects the localization of CYCS protein]		 CTD PMID:19682444 PMID:19951573 PMID:34455488 PMID:35414346 PMID:36462176 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 increases expression EXP Streptozocin results in increased expression of CYP11B2 mRNA; Streptozocin results in increased expression of CYP11B2 protein CTD PMID:16043663 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression		 ISO
EXP		 Metformin promotes the reaction [Streptozocin results in increased expression of CYP1A1 mRNA]; Streptozocin promotes the reaction [Dietary Fats results in decreased expression of CYP1A1 mRNA]
[resveratrol co-treated with Streptozocin] results in increased expression of CYP1A1 mRNA		 CTD PMID:22342832 PMID:25905778 PMID:29382564 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression
multiple interactions
increases expression		 ISO
EXP		 Streptozocin results in decreased expression of CYP1A2 protein
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP1A2 mRNA
Streptozocin results in decreased expression of CYP1A2 mRNA
[resveratrol co-treated with Streptozocin] results in decreased expression of CYP1A2 mRNA; [Streptozocin results in increased expression of CYP1A2 protein] which results in increased metabolism of Diazinon		 CTD PMID:12700423 PMID:17442507 PMID:25905778 PMID:29127188 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CYP26A1 mRNA CTD PMID:25905778 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CYP26B1 mRNA CTD PMID:25905778 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP27A1 mRNA CTD PMID:29382564 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in decreased expression of CYP2A1 mRNA
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CYP2A22 mRNA		 CTD PMID:25905778 PMID:33484791 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CYP2A4 mRNA CTD PMID:33484791 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of CYP2B1 mRNA
[resveratrol co-treated with Streptozocin] results in increased expression of CYP2B1 mRNA		 CTD PMID:25905778 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CYP2B13 mRNA CTD PMID:29127188 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression
multiple interactions		 ISO Streptozocin results in increased expression of CYP2B10 mRNA
Berberine inhibits the reaction [Streptozocin results in increased expression of CYP2B10 mRNA]; Streptozocin promotes the reaction [Dietary Fats results in decreased expression of CYP2B10 mRNA]		 CTD PMID:22342832 PMID:29382564 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP2C11 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP2C11 protein CTD PMID:24815820 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression
multiple interactions
increases expression		 ISO
EXP		 Streptozocin results in decreased expression of CYP2E1 protein
[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased activity of CYP2E1 protein
Streptozocin results in increased expression of CYP2E1 mRNA; Streptozocin results in increased expression of CYP2E1 protein		 CTD PMID:11752103 PMID:12700423 PMID:14693714 PMID:24815820 PMID:25905778 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 increases expression EXP Streptozocin results in increased expression of CYP2J4 mRNA CTD PMID:25905778 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794 		JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of CYP4A1 mRNA
[Dietary Fats co-treated with Streptozocin] results in increased expression of CYP4A1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of CYP4A1 protein; [Resveratrol co-treated with Streptozocin] results in decreased expression of CYP4A1 mRNA		 CTD PMID:24815820 PMID:25905778 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464 		JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of CYP4A2 protein
[Dietary Fats co-treated with Streptozocin] results in increased expression of CYP4A2 mRNA; Trientine promotes the reaction [Streptozocin results in decreased expression of CYP4A2 protein]		 CTD PMID:19634143 PMID:24815820 NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165 		JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP4F14 mRNA CTD PMID:29127188 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of CYP7A1 mRNA
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein; Acrylamide inhibits the reaction [Streptozocin results in increased expression of CYP7A1 mRNA]		 CTD PMID:10393316 PMID:29382564 PMID:31100278 PMID:34896238 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7B1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP7B1 mRNA CTD PMID:29127188 PMID:29382564 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions
increases expression		 EXP
ISO		 [resveratrol co-treated with Streptozocin] results in decreased expression of CYP8B1 mRNA; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CYP8B1 mRNA]; Streptozocin inhibits the reaction [resveratrol results in increased expression of CYP8B1 mRNA]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP8B1 mRNA
Streptozocin results in increased expression of CYP8B1 mRNA; Streptozocin results in increased expression of CYP8B1 protein		 CTD PMID:10393316 PMID:25905778 PMID:29382564 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166 		JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 multiple interactions
increases expression		 ISO montelukast inhibits the reaction [Streptozocin results in increased expression of CYSLTR1 mRNA]; montelukast inhibits the reaction [Streptozocin results in increased expression of CYSLTR1 protein]
Streptozocin results in increased expression of CYSLTR1 mRNA; Streptozocin results in increased expression of CYSLTR1 protein		 CTD PMID:27702591 NCBI chr  X:71,661,421...71,690,012
Ensembl chr  X:71,663,821...71,690,121 		JBrowse link
G Cyyr1 cysteine and tyrosine rich 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CYYR1 mRNA CTD PMID:25905778 NCBI chr11:24,557,620...24,664,007
Ensembl chr11:24,515,316...24,663,961 		JBrowse link
G Dao D-amino-acid oxidase increases expression
multiple interactions		 EXP Streptozocin results in increased expression of DAO protein
Trientine inhibits the reaction [Streptozocin results in increased expression of DAO protein]		 CTD PMID:19634143 NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741 		JBrowse link
G Dapk1 death associated protein kinase 1 decreases expression EXP Streptozocin results in decreased expression of DAPK1 mRNA CTD PMID:25905778 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
G Dapl1 death associated protein-like 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of DAPL1 mRNA CTD PMID:33484791 NCBI chr 3:43,960,993...43,980,940
Ensembl chr 3:43,960,810...43,980,940 		JBrowse link
G Dbn1 drebrin 1 decreases expression EXP Streptozocin results in decreased expression of DBN1 protein CTD PMID:23333261 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984 		JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 affects expression ISO Streptozocin affects the expression of DBT mRNA CTD PMID:18583417 NCBI chr 2:204,481,744...204,510,612
Ensembl chr 2:204,481,737...204,510,609 		JBrowse link
G Dcc DCC netrin 1 receptor multiple interactions
increases expression		 ISO NTN1 protein promotes the reaction [Streptozocin results in increased expression of DCC mRNA]; NTN1 protein promotes the reaction [Streptozocin results in increased expression of DCC protein]
Streptozocin results in increased expression of DCC mRNA; Streptozocin results in increased expression of DCC protein		 CTD PMID:29059224 NCBI chr18:64,868,987...65,972,783
Ensembl chr18:64,873,898...65,972,740 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of DDIT3; Streptozocin results in increased expression of DDIT3 mRNA; Streptozocin results in increased expression of DDIT3 protein
streptozocin increases expression of Ddit3 protein in heart
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of DDIT3 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of DDIT3 mRNA; Bilirubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of DDIT3 mRNA]; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of DDIT3 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein]
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of DDIT3 mRNA]; [Streptozocin co-treated with bisphenol A] results in increased expression of DDIT3 protein; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of DDIT3 mRNA; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of DDIT3 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of DDIT3 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of DDIT3 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of DDIT3 protein; FGF21 protein affects the reaction [Streptozocin results in increased expression of DDIT3]; Streptozocin promotes the reaction [bisphenol A results in increased expression of DDIT3 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein]		 CTD
RGD		 PMID:23499715 PMID:24967692 PMID:29935216 PMID:30980806 PMID:34801538 More... RGD:156430337 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of DDIT4 mRNA CTD PMID:25905778 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of DECR1 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of DECR1 mRNA]		 CTD PMID:16684804 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018 		JBrowse link
G Derl1 derlin 1 multiple interactions
increases expression		 EXP 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of DERL1 protein] CTD PMID:30980806 NCBI chr 7:89,404,413...89,427,095
Ensembl chr 7:89,404,417...89,427,145 		JBrowse link
G Derl3 derlin 3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of DERL3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of DERL3 mRNA] CTD PMID:33484791 NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027 		JBrowse link
G Des desmin multiple interactions
increases expression		 EXP Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of DES protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of DES protein] CTD PMID:12197670 PMID:17624267 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of DGAT1 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of DGAT1 mRNA] CTD PMID:33812996 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions EXP [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of DGAT2 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of DGAT2 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of DGAT2 mRNA CTD PMID:35786680 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428 		JBrowse link
G Dgkh diacylglycerol kinase, eta multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of DGKH mRNA CTD PMID:20665664 NCBI chr15:53,981,079...54,150,470
Ensembl chr15:53,991,481...54,150,706 		JBrowse link
G Dhrs7 dehydrogenase/reductase 7 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of DHRS7 mRNA CTD PMID:25905778 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of DHRS9 mRNA CTD PMID:29127188 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein multiple interactions ISO [Streptozocin co-treated with NQO1 protein mutant form] results in increased secretion of DIABLO protein CTD PMID:23458895 NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387 		JBrowse link
G Dio1 iodothyronine deiodinase 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of DIO1 mRNA CTD PMID:25905778 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Dio3 iodothyronine deiodinase 3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of DIO3 mRNA CTD PMID:33484791 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660 		JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase multiple interactions
increases expression		 EXP Trientine inhibits the reaction [Streptozocin results in increased expression of DLAT protein] CTD PMID:21136691 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479 		JBrowse link
G Dld dihydrolipoamide dehydrogenase increases expression
multiple interactions		 EXP Streptozocin results in increased expression of DLD protein
Trientine inhibits the reaction [Streptozocin results in increased expression of DLD protein]		 CTD PMID:21136691 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 multiple interactions
decreases expression		 EXP Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of DLG4 protein]; Memantine inhibits the reaction [Streptozocin results in decreased expression of DLG4 protein] CTD PMID:24333387 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153 		JBrowse link
G Dlgap2 DLG associated protein 2 multiple interactions
decreases expression		 EXP Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of DLGAP2 mRNA]; Memantine inhibits the reaction [Streptozocin results in decreased expression of DLGAP2 mRNA] CTD PMID:24333387 NCBI chr16:74,786,771...75,496,402
Ensembl chr16:74,791,509...75,496,407 		JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase multiple interactions
increases expression		 EXP Trientine inhibits the reaction [Streptozocin results in increased expression of DLST protein] CTD PMID:19634143 PMID:21136691 NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296 		JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of DMBT1 mRNA CTD PMID:25905778 NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478 		JBrowse link
G Dmbt1l1 deleted in malignant brain tumors 1 like 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CDCP3 mRNA CTD PMID:33484791 NCBI chr 1:185,949,897...186,084,340
Ensembl chr 1:185,949,881...186,084,338 		JBrowse link
G Dnah5 dynein, axonemal, heavy chain 5 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of DNAH5 mRNA CTD PMID:33484791 NCBI chr 2:78,937,788...79,255,551
Ensembl chr 2:78,937,800...79,254,890 		JBrowse link
G Dnm1l dynamin 1-like multiple interactions
increases expression		 EXP
ISO		 ferulic acid inhibits the reaction [Streptozocin results in increased expression of DNM1L protein]
[Dietary Fats co-treated with Streptozocin] results in increased expression of DNM1L mRNA		 CTD PMID:31029786 PMID:33812996 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482 		JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions
decreases expression		 ISO
EXP		 [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT1 protein; Folic Acid deficiency promotes the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]; Folic Acid inhibits the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]
[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 mRNA]; [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 mRNA]]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 protein]]		 CTD PMID:28422052 PMID:29127188 PMID:36547818 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3A mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3A protein CTD PMID:29127188 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta multiple interactions
increases expression		 ISO
EXP		 [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3B mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3B protein
Streptozocin results in increased expression of DNMT3B mRNA		 CTD PMID:29127188 PMID:37081038 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Dpp4 dipeptidylpeptidase 4 increases response to substance
increases expression
decreases expression
decreases activity		 EXP DPP4 results in increased susceptibility to Streptozocin
Streptozocin results in increased expression of DPP4 mRNA
Streptozocin results in decreased expression of DPP4 protein
Streptozocin results in decreased activity of DPP4 protein		 CTD PMID:16045816 PMID:18931022 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 increases expression EXP Streptozocin results in increased expression of ECHS1 protein CTD PMID:21136691 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884 		JBrowse link
G Edaradd EDAR associated via death domain multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of EDARADD mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of EDARADD mRNA] CTD PMID:33484791 NCBI chr17:85,866,629...85,910,612
Ensembl chr17:85,656,905...85,910,447 		JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression EXP Streptozocin results in increased expression of EDEM1 mRNA CTD PMID:25905778 NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717 		JBrowse link
G Edem3 ER degradation enhancing alpha-mannosidase like protein 3 multiple interactions ISO [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 protein CTD PMID:38282657 NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523 		JBrowse link
G Edn1 endothelin 1 multiple interactions
increases expression		 EXP
ISO		 Bezafibrate inhibits the reaction [Streptozocin results in increased expression of EDN1 mRNA]
diphenyleneiodonium inhibits the reaction [Streptozocin promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate]]; Streptozocin promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate]		 CTD PMID:12458661 PMID:12967931 PMID:20691780 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Efna3 ephrin A3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of EFNA3 mRNA CTD PMID:33484791 NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736 		JBrowse link
G Efnb2 ephrin B2 affects expression ISO Streptozocin affects the expression of EFNB2 mRNA CTD PMID:26073000 NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391 		JBrowse link
G Egfr epidermal growth factor receptor increases expression EXP Streptozocin results in increased expression of EGFR mRNA CTD PMID:37081038 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression EXP Streptozocin results in increased expression of EHHADH mRNA CTD PMID:25905778 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation		 ISO
EXP		 [Dietary Fats co-treated with Streptozocin] results in increased expression of EIF2AK3 protein; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of EIF2AK3 protein]
Streptozocin results in increased phosphorylation of EIF2AK3 protein
[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased phosphorylation of EIF2AK3 protein]		 CTD PMID:33812996 PMID:34801538 PMID:38049026 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of EIF2S1 protein; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of EIF2S1 protein] CTD PMID:33812996 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
increases expression		 EXP vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of EIF4EBP1 mRNA] CTD PMID:16684804 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Elk1 ETS transcription factor ELK1 increases phosphorylation EXP Streptozocin results in increased phosphorylation of ELK1 protein CTD PMID:12642375 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713 		JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ELOVL7 mRNA CTD PMID:29127188 NCBI chr 2:39,789,229...39,858,579
Ensembl chr 2:39,789,250...39,856,845 		JBrowse link
G Eno1 enolase 1 increases expression EXP Streptozocin results in increased expression of ENO1 protein CTD PMID:24924950 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 		JBrowse link
G Eno1-ps1 enolase 1, pseudogene 1 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of ENO1-PS1 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ENO1-PS1 protein]		 CTD PMID:19634143 NCBI chr 3:57,576,643...57,578,321
Ensembl chr 3:57,576,709...57,578,013 		JBrowse link
G Eno2 enolase 2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of ENO2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ENO2 mRNA] CTD PMID:33484791 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980 		JBrowse link
G Enpep glutamyl aminopeptidase multiple interactions
increases activity		 EXP
ISO		 [resveratrol co-treated with Streptozocin] results in decreased expression of ENPEP mRNA
Streptozocin results in increased activity of ENPEP protein		 CTD PMID:25905778 PMID:28468961 NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of ENPP2 mRNA CTD PMID:25905778 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827 		JBrowse link
G Ep300 E1A binding protein p300 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of EP300 mRNA
3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of EP300 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of EP300 mRNA]		 CTD PMID:22228707 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Epcam epithelial cell adhesion molecule multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of EPCAM mRNA CTD PMID:25905778 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127 		JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of EPHX1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of EPHX1 protein]		 CTD PMID:19634143 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Ephx2 epoxide hydrolase 2 increases expression
decreases response to substance
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of EPHX2 protein
EPHX2 gene mutant form results in decreased susceptibility to Streptozocin
EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased activity of RELA protein]; EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]		 CTD PMID:21832210 PMID:23611540 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615 		JBrowse link
G Epo erythropoietin multiple interactions
increases expression
decreases expression		 EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of EPO protein; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of EPO protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of EPO mRNA]; Simvastatin inhibits the reaction [Streptozocin results in decreased expression of EPO protein]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of EPO mRNA] CTD PMID:19958114 PMID:20821229 PMID:34391751 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Epor erythropoietin receptor multiple interactions
increases expression
decreases expression		 EXP Enalapril inhibits the reaction [Streptozocin results in increased expression of EPOR mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of EPOR protein]; Simvastatin inhibits the reaction [Streptozocin results in decreased expression of EPOR protein]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of EPOR mRNA]
Streptozocin results in increased expression of EPOR mRNA; Streptozocin results in increased expression of EPOR protein		 CTD PMID:19958114 PMID:20821229 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ERCC1 mRNA; Streptozocin results in increased expression of ERCC1 protein
3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of ERCC1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of ERCC1 mRNA]		 CTD PMID:22228707 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit multiple interactions
increases expression		 EXP 3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of ERCC4 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of ERCC4 mRNA]
Streptozocin results in increased expression of ERCC4 mRNA; Streptozocin results in increased expression of ERCC4 protein		 CTD PMID:22228707 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Ermap erythroblast membrane associated protein (Scianna blood group) multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of ERMAP mRNA CTD PMID:33484791 NCBI chr 5:132,788,847...132,803,030
Ensembl chr 5:132,789,991...132,802,847 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases expression		 EXP
ISO		 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of ERN1 protein modified form]; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ERN1 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ERN1 protein]
[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of ERN1 protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of ERN1 protein]		 CTD PMID:20399799 PMID:34801538 PMID:35961541 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of ERN2 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ERN2 protein] CTD PMID:33484791 NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases expression
decreases expression		 ISO
EXP		 bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR1 mRNA]; Ethinyl Estradiol inhibits the reaction [Streptozocin results in decreased expression of ESR1 mRNA]; octylphenol inhibits the reaction [Streptozocin results in decreased expression of ESR1 mRNA]
Streptozocin results in increased expression of ESR1
[Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of ESR1 protein		 CTD PMID:24781736 PMID:30421503 PMID:32469605 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
decreases expression		 ISO bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]; bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR2 protein]; ESR2 protein affects the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; Ethinyl Estradiol inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]; octylphenol inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]
Streptozocin results in decreased expression of ESR2 mRNA; Streptozocin results in decreased expression of ESR2 protein		 CTD PMID:23471663 PMID:24781736 PMID:35051763 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Etfa electron transfer flavoprotein subunit alpha decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of ETFA protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ETFA protein]		 CTD PMID:19634143 NCBI chr 8:55,835,115...55,891,890
Ensembl chr 8:55,835,134...55,891,969 		JBrowse link
G Etfb electron transfer flavoprotein subunit beta decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of ETFB protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ETFB protein]		 CTD PMID:19634143 NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068 		JBrowse link
G Etfdh electron transfer flavoprotein dehydrogenase affects expression ISO Streptozocin affects the expression of ETFDH mRNA CTD PMID:18583417 NCBI chr 2:164,740,547...164,762,754
Ensembl chr 2:164,729,749...164,762,745 		JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor multiple interactions
decreases expression		 ISO SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of ETS1 mRNA] CTD PMID:27629361 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010 		JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of EYA2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of EYA2 mRNA] CTD PMID:33484791 NCBI chr 3:154,335,598...154,519,006
Ensembl chr 3:154,335,400...154,518,793 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of EZH2 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of EZH2 protein CTD PMID:29127188 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G F3 coagulation factor III, tissue factor decreases activity EXP Streptozocin results in decreased activity of F3 protein CTD PMID:32864810 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of FABP4 mRNA CTD PMID:29127188 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fabp7 fatty acid binding protein 7 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of FABP7 mRNA CTD PMID:29127188 NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880 		JBrowse link
G Fadd Fas associated via death domain multiple interactions
increases expression		 EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FADD protein] CTD PMID:28856781 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression EXP Streptozocin results in decreased expression of FADS1 mRNA CTD PMID:25246140 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734 		JBrowse link
G Fam184a family with sequence similarity 184, member A multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of FAM184A mRNA CTD PMID:33484791 NCBI chr20:32,934,424...33,056,626
Ensembl chr20:32,934,636...33,056,652 		JBrowse link
G Fars2 phenylalanyl-tRNA synthetase 2, mitochondrial affects expression ISO Streptozocin affects the expression of FARS2 mRNA CTD PMID:18583417 NCBI chr17:28,319,215...28,746,217
Ensembl chr17:28,319,280...28,746,337 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression		 EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FAS protein] CTD PMID:28856781 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand multiple interactions
increases expression		 EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FASLG protein]; rosiglitazone inhibits the reaction [Streptozocin results in increased expression of FASLG mRNA]
Streptozocin results in increased expression of FASLG mRNA; Streptozocin results in increased expression of FASLG protein		 CTD PMID:21791967 PMID:28856781 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fasn fatty acid synthase multiple interactions
increases expression
decreases expression		 EXP
ISO		 Allopurinol inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of FASN protein]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of FASN mRNA]; INS protein inhibits the reaction [Streptozocin results in decreased expression of FASN mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of FASN protein]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of FASN mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]; esculetin promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of FASN mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA]
Streptozocin results in increased expression of FASN mRNA; Streptozocin results in increased expression of FASN protein		 CTD PMID:20219977 PMID:23647015 PMID:27769711 PMID:29988851 PMID:33812996 More... NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Faxc failed axon connections homolog, metaxin like GST domain containing multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of FAXC mRNA CTD PMID:33484791 NCBI chr 5:35,480,137...35,539,741
Ensembl chr 5:35,480,402...35,544,446 		JBrowse link
G Fbp1 fructose-bisphosphatase 1 increases activity
multiple interactions		 EXP Streptozocin results in increased activity of FBP1 protein
citronellol inhibits the reaction [Streptozocin results in increased activity of FBP1 protein]		 CTD PMID:26944432 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071 		JBrowse link
G Fbp2 fructose-bisphosphatase 2 multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FBP2 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of FBP2 protein CTD PMID:25446853 NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698 		JBrowse link
G Fbxo32 F-box protein 32 increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of FBXO32 protein
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of FBXO32 protein]		 CTD PMID:30635400 PMID:30980806 NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436 		JBrowse link
G Fcer1g Fc epsilon receptor Ig multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of FCER1G mRNA CTD PMID:25905778 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Fcgr2a Fc gamma receptor 2A increases expression
multiple interactions		 EXP Streptozocin results in increased expression of FCGR3 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of FCGR3 mRNA]		 CTD PMID:16684804 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967 		JBrowse link
G Fgf17 fibroblast growth factor 17 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of FGF17 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of FGF17 mRNA] CTD PMID:32303808 NCBI chr15:45,711,498...45,717,622
Ensembl chr15:45,711,998...45,717,063 		JBrowse link
G Fgf19 fibroblast growth factor 19 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of FGF15 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of FGF15 protein CTD PMID:29382564 NCBI chr 1:200,056,526...200,060,980
Ensembl chr 1:200,056,644...200,060,287 		JBrowse link
G Fgf21 fibroblast growth factor 21 multiple interactions
affects response to substance		 ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of FGF21 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of FGF21 mRNA; FGF21 protein affects the reaction [Streptozocin results in increased expression of AIFM1]; FGF21 protein affects the reaction [Streptozocin results in increased expression of CASP12 protein modified form]; FGF21 protein affects the reaction [Streptozocin results in increased expression of DDIT3]; Glucagon analog promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of FGF21 protein]
FGF21 protein affects the susceptibility to Streptozocin		 CTD PMID:23499715 PMID:29127188 PMID:29988851 NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 multiple interactions
decreases expression		 EXP rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of FGFR1] CTD PMID:24136780 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fh fumarate hydratase affects expression ISO Streptozocin affects the expression of FH1 mRNA CTD PMID:18583417 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
G Fis1 fission, mitochondrial 1 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of FIS1 mRNA CTD PMID:33812996 NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377 		JBrowse link
G Fitm2 fat storage-inducing transmembrane protein 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of FITM2 mRNA CTD PMID:25905778 NCBI chr 3:152,141,346...152,147,858
Ensembl chr 3:152,141,346...152,147,858 		JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B multiple interactions ISO Streptozocin promotes the reaction [bisphenol A results in decreased expression of FKBP1B mRNA]; Streptozocin promotes the reaction [octylphenol results in decreased expression of FKBP1B mRNA] CTD PMID:29935216 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653 		JBrowse link
G Flacc1 flagellum associated containing coiled-coil domains 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of FLACC1 mRNA CTD PMID:33484791 NCBI chr 9:60,315,581...60,343,692
Ensembl chr 9:60,315,582...60,343,648 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 multiple interactions
increases expression		 EXP
ISO		 Simvastatin inhibits the reaction [Streptozocin results in increased expression of FLT1 mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased expression of FLT1 protein]; Streptozocin results in increased phosphorylation of and results in increased expression of FLT1 protein CTD PMID:20821229 PMID:26073000 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 increases expression EXP Streptozocin results in increased expression of FMO2 mRNA CTD PMID:25905778 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308 		JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of FMO4 mRNA CTD PMID:25905778 NCBI chr13:75,154,683...75,172,874
Ensembl chr13:75,154,684...75,172,874 		JBrowse link
G Fn1 fibronectin 1 increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of FN1; Streptozocin results in increased expression of FN1 mRNA; Streptozocin results in increased expression of FN1 protein
[AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein; [fatostatin co-treated with Streptozocin] results in increased expression of FN1 mRNA; [fatostatin co-treated with Streptozocin] results in increased expression of FN1 protein; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of FN1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of FN1 protein; AM6545 inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; CREB1 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of FN1 protein]
3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; [Streptozocin co-treated with Cadmium] results in increased expression of FN1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein; Aspirin inhibits the reaction [Streptozocin results in increased expression of FN1]; benazepril inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Carvedilol inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; esculetin inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; esculetin inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of FN1 protein]; Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased expression of FN1 protein]]; Trientine inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; XLF-III-43 inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]		 CTD PMID:11798618 PMID:12140129 PMID:14586741 PMID:16973718 PMID:19895808 More... NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 ISO formononetin inhibits the reaction [Streptozocin results in increased expression of FOS mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of FOS protein]
Streptozocin results in increased expression of FOS mRNA; Streptozocin results in increased expression of FOS protein		 CTD PMID:35315182 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of FOSB mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of FOSB mRNA] CTD PMID:33484791 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Foxa2 forkhead box A2 multiple interactions EXP copper bis(3,5-diisopropylsalicylate) inhibits the reaction [Streptozocin results in decreased expression of FOXA2] CTD PMID:23795780 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Foxo1 forkhead box O1 multiple interactions
decreases phosphorylation
decreases expression
increases acetylation		 ISO
EXP		 [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of FOXO1 protein; resveratrol inhibits the reaction [Streptozocin results in increased acetylation of FOXO1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of FOXO1 protein]
Streptozocin results in decreased phosphorylation of FOXO1 protein
Streptozocin results in decreased expression of FOXO1 mRNA
[Dietary Fats co-treated with Streptozocin] affects the localization of FOXO1 protein; Butyric Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] affects the localization of FOXO1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] affects the localization of FOXO1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of FOXO1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of and results in decreased activity of FOXO1 protein]; Streptozocin results in increased phosphorylation of and results in decreased activity of FOXO1 protein; Tribulus extract inhibits the reaction [Streptozocin results in decreased phosphorylation of FOXO1 protein]		 CTD PMID:22733486 PMID:24889822 PMID:26522834 PMID:27270450 PMID:36627075 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Foxo3 forkhead box O3 decreases expression
multiple interactions
increases expression		 EXP
ISO		 Streptozocin results in decreased expression of FOXO3 protein
[Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in increased phosphorylation of FOXO3 protein; [Streptozocin co-treated with Resveratrol] results in increased phosphorylation of FOXO3 protein; Resveratrol inhibits the reaction [Streptozocin results in increased expression of FOXO3 protein]
Streptozocin results in increased expression of FOXO3 protein; Streptozocin results in increased expression of FOXO3 protein modified form		 CTD PMID:17082237 PMID:18703049 PMID:23792339 PMID:31062909 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Fshb follicle stimulating hormone subunit beta decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in decreased expression of FSHB protein
[Streptozocin co-treated with Fructose] results in decreased expression of FSHB protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in decreased expression of FSHB protein]
Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of FSHB protein]; vitexin inhibits the reaction [Streptozocin results in decreased expression of FSHB protein]		 CTD PMID:19931367 PMID:30365938 PMID:34656705 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of FTH1 mRNA; Omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FTH1 mRNA]; Omaveloxolone promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FTH1 mRNA] CTD PMID:32410268 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of FXYD2 mRNA CTD PMID:25905778 NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions
increases expression
decreases expression
increases activity
decreases activity		 EXP
ISO		 4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; bis(maltolato)oxovanadium(IV) inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; citronellol inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; Plant Extracts inhibits the reaction [Streptozocin results in decreased activity of G6PC1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; plumbagin inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; Polysaccharides inhibits the reaction [Streptozocin results in decreased activity of G6PC1 protein]; Tribulus extract inhibits the reaction [Streptozocin results in increased expression of G6PC1 protein]; Trientine inhibits the reaction [Streptozocin results in increased expression of G6PC1 protein]
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of G6PC1 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PC1 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of G6PC1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of G6PC1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; esculetin promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PC1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of G6PC1 mRNA]
Streptozocin results in decreased expression of G6PC1 mRNA
Streptozocin results in increased expression of G6PC1 mRNA; Streptozocin results in increased expression of G6PC1 protein		 CTD PMID:12446591 PMID:19634143 PMID:22960630 PMID:25446853 PMID:25641191 More... NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G G6pc3 glucose 6 phosphatase catalytic subunit 3 decreases activity
multiple interactions		 EXP Streptozocin results in decreased activity of G6PC3 protein
Glyburide inhibits the reaction [Streptozocin results in decreased activity of G6PC3 protein]; Hesperidin inhibits the reaction [Streptozocin results in decreased activity of G6PC3 protein]		 CTD PMID:31345080 NCBI chr10:87,146,987...87,151,223
Ensembl chr10:87,146,901...87,151,221 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
decreases expression
decreases activity		 EXP
ISO		 2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of G6PD mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of G6PD protein]; 4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; [Phytic Acid co-treated with Inositol] inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; [Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein; [Streptozocin co-treated with Niacinamide] affects the activity of G6PD protein; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; citronellol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; G6PD protein promotes the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; G6PD protein promotes the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; geraniol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; Glyburide inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; Hesperidin inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein]; NFE2L2 protein inhibits the reaction [Streptozocin results in decreased expression of G6PD mRNA]; NFE2L2 protein inhibits the reaction [Streptozocin results in decreased expression of G6PD protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] affects the activity of G6PD protein]
Streptozocin results in decreased expression of G6PD mRNA; Streptozocin results in decreased expression of G6PD protein
[Streptozocin co-treated with Dietary Fats] results in decreased activity of G6PD protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of G6PD protein]		 CTD PMID:19059388 PMID:19133311 PMID:19682444 PMID:24923654 PMID:25641191 More... NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of GABRA4 mRNA CTD PMID:33484791 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844 		JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of GABRR1 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of GABRR1 mRNA] CTD PMID:32303808 NCBI chr 5:47,524,151...47,561,228
Ensembl chr 5:47,524,151...47,561,228 		JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions
decreases expression		 EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of GAD1 protein; Curcumin inhibits the reaction [Streptozocin results in decreased expression of GAD1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GAD1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GAD1 protein] CTD PMID:23267840 PMID:35085591 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta multiple interactions EXP
ISO		 [resveratrol co-treated with Streptozocin] results in increased expression of GADD45B mRNA
[Streptozocin co-treated with Dietary Fats] results in increased expression of GADD45B mRNA		 CTD PMID:25905778 PMID:29127188 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Galt galactose-1-phosphate uridylyltransferase decreases expression EXP Streptozocin results in decreased expression of GALT mRNA CTD PMID:25905778 NCBI chr 5:56,927,039...56,930,284
Ensembl chr 5:56,926,724...56,930,265 		JBrowse link
G Gas6 growth arrest specific 6 increases expression EXP Streptozocin results in increased expression of GAS6 protein CTD PMID:12644472 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Gatm glycine amidinotransferase multiple interactions
decreases expression		 EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of GATM protein] CTD PMID:19634143 NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129 		JBrowse link
G Gcg glucagon multiple interactions
decreases expression		 EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of GCG protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of GCG mRNA; Butyric Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GCG protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GCG protein]; rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of GCG mRNA]; Sitagliptin Phosphate inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCG mRNA] CTD PMID:18998217 PMID:23466488 PMID:27270450 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929 		JBrowse link
G Gck glucokinase multiple interactions
decreases expression		 ISO
EXP		 [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of GCK protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of GCK protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of GCK mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of GCK protein; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA]
Streptozocin results in decreased expression of GCK mRNA
[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of GCK mRNA]; repaglinide analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA]; repaglinide inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA]		 CTD PMID:25446853 PMID:26522834 PMID:27038876 PMID:27769711 PMID:29127188 More... NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
decreases expression		 EXP
ISO		 [Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC mRNA; [Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC protein; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of GCLC mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of GCLC protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC mRNA]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC mRNA]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC protein]
Streptozocin results in decreased expression of GCLC mRNA; Streptozocin results in decreased expression of GCLC protein
[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCLC mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCLC mRNA]		 CTD PMID:21439372 PMID:33359794 PMID:33639173 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCLM mRNA CTD PMID:33359794 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 increases expression EXP Streptozocin results in increased expression of GCNT2 mRNA CTD PMID:25905778 NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611 		JBrowse link
G Gda guanine deaminase increases expression EXP Streptozocin results in increased expression of GDA mRNA CTD PMID:25905778 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416 		JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions
decreases expression		 EXP Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of GDNF protein] CTD PMID:38049026 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions
decreases expression
increases expression		 EXP
ISO		 Ibuprofen inhibits the reaction [Streptozocin results in increased expression of GFAP mRNA]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of GFAP protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of GFAP mRNA]; Memantine inhibits the reaction [Streptozocin results in increased expression of GFAP protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased expression of GFAP protein]
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GFAP protein]; Physostigmine inhibits the reaction [Streptozocin results in decreased expression of GFAP protein]
Streptozocin results in increased expression of GFAP mRNA; Streptozocin results in increased expression of GFAP protein		 CTD PMID:24333387 PMID:28499986 PMID:38049026 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Gfm1 G elongation factor, mitochondrial 1 affects expression ISO Streptozocin affects the expression of GFM1 mRNA CTD PMID:18583417 NCBI chr 2:151,700,573...151,745,477
Ensembl chr 2:151,700,564...151,745,471 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of GGT1 protein
[resveratrol co-treated with Streptozocin] results in increased expression of GGT1 mRNA; Trientine inhibits the reaction [Streptozocin results in decreased expression of GGT1 protein]		 CTD PMID:19634143 PMID:25905778 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
G Ghr growth hormone receptor multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of GHR mRNA CTD PMID:25905778 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide multiple interactions EXP GHRL protein promotes the reaction [Streptozocin results in decreased expression of CARTPT mRNA]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of FASN mRNA]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA] CTD PMID:20219977 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Gk glycerol kinase decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in decreased expression of GK mRNA
[Dietary Fats co-treated with Streptozocin] results in increased expression of GK mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GK mRNA]		 CTD PMID:25905778 PMID:33812996 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631 		JBrowse link
G Glb1 galactosidase, beta 1 increases expression
multiple interactions		 ISO Streptozocin results in increased expression of GLB1 protein
2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of GLB1 protein]; ARG1 gene mutant form inhibits the reaction [Streptozocin results in increased expression of GLB1 protein]		 CTD PMID:29673160 NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127 		JBrowse link
G Glis1 GLIS family zinc finger 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of GLIS1 mRNA CTD PMID:33484791 NCBI chr 5:122,222,155...122,412,141
Ensembl chr 5:122,222,128...122,412,141 		JBrowse link
G Glo1 glyoxalase 1 multiple interactions EXP [Streptozocin co-treated with Niacinamide] results in decreased activity of GLO1 protein; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GLO1 protein]; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GLO1 protein] CTD PMID:21439372 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649 		JBrowse link
G Glp1r glucagon-like peptide 1 receptor multiple interactions EXP [Fructose co-treated with Streptozocin] results in decreased expression of GLP1R mRNA; Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased expression of GLP1R mRNA] CTD PMID:31468622 NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241 		JBrowse link
G Glud1 glutamate dehydrogenase 1 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of GLUD1 mRNA; repaglinide analog affects the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GLUD1 mRNA]; repaglinide inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GLUD1 mRNA] CTD PMID:35702883 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957 		JBrowse link
G Glul glutamate-ammonia ligase multiple interactions
decreases expression		 EXP [resveratrol co-treated with Streptozocin] results in increased expression of GLUL mRNA; resveratrol inhibits the reaction [Streptozocin results in decreased expression of GLUL mRNA]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of GLUL protein]
Streptozocin results in decreased expression of GLUL mRNA; Streptozocin results in decreased expression of GLUL protein		 CTD PMID:25905778 PMID:26677078 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Gna11 G protein subunit alpha 11 multiple interactions
increases expression		 EXP acetovanillone inhibits the reaction [Streptozocin results in increased expression of GNA11 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNA11 protein] CTD PMID:20691780 NCBI chr 7:8,163,520...8,177,863
Ensembl chr 7:8,162,750...8,179,812 		JBrowse link
G Gnai2 G protein subunit alpha i2 multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI2 protein]; diphenyleneiodonium inhibits the reaction [Streptozocin results in decreased expression of GNAI2 protein] CTD PMID:18441196 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gnai3 G protein subunit alpha i3 multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI3 protein]; diphenyleneiodonium inhibits the reaction [Streptozocin results in decreased expression of GNAI3 protein] CTD PMID:18441196 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742 		JBrowse link
G Gnaq G protein subunit alpha q multiple interactions
increases expression		 EXP acetovanillone inhibits the reaction [Streptozocin results in increased expression of GNAQ protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNAQ protein] CTD PMID:20691780 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
G Gngt1 G protein subunit gamma transducin 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of GNGT1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GNGT1 mRNA] CTD PMID:33484791 NCBI chr 4:32,006,267...32,009,252
Ensembl chr 4:32,006,267...32,009,252 		JBrowse link
G Gnmt glycine N-methyltransferase multiple interactions
increases expression
increases activity		 EXP Folic Acid inhibits the reaction [Streptozocin results in increased activity of GNMT protein]
Streptozocin results in increased expression of GNMT mRNA; Streptozocin results in increased expression of GNMT protein		 CTD PMID:16835399 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions
increases secretion		 EXP
ISO		 [Resveratrol co-treated with Streptozocin] results in decreased expression of GOT1 mRNA; Atorvastatin inhibits the reaction [Streptozocin results in increased secretion of GOT1 protein]
[Streptozocin co-treated with Dietary Fats] results in increased expression of GOT1 protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of GOT1 protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of GOT1 protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GOT1 protein]		 CTD PMID:25905778 PMID:30657622 PMID:35961541 PMID:37482253 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of GOT2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of GOT2 protein]		 CTD PMID:19634143 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
G Gpc1 glypican 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of GPC1 mRNA CTD PMID:29127188 NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047 		JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of GPD1 mRNA CTD PMID:25905778 NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529 		JBrowse link
G Gprc6a G protein-coupled receptor, class C, group 6, member A multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of GPRC6A mRNA; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPRC6A mRNA] CTD PMID:27488359 NCBI chr20:30,922,106...30,943,412
Ensembl chr20:30,922,106...30,943,412 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases activity
increases secretion
increases expression		 EXP
ISO		 4-hydroxyisoleucine inhibits the reaction [Streptozocin results in increased expression of GPT protein]; [Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein; [Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein; allyl isothiocyanate inhibits the reaction [Streptozocin promotes the reaction [Dietary Fats results in increased expression of GPT protein]]; Atorvastatin inhibits the reaction [Streptozocin results in increased secretion of GPT protein]; Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; Glyburide inhibits the reaction [Streptozocin results in increased activity of GPT protein]; mangiferin inhibits the reaction [Streptozocin results in increased activity of GPT protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; naringenin inhibits the reaction [Streptozocin results in increased activity of GPT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of GPT protein]; sodium tungstate(VI) inhibits the reaction [Streptozocin results in increased activity of GPT protein]; Streptozocin promotes the reaction [Dietary Fats results in increased expression of GPT protein]; Tribulus extract inhibits the reaction [Streptozocin results in increased activity of GPT protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]
[Acrylamide co-treated with Streptozocin] results in increased activity of GPT protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein; [omaveloxolone analog co-treated with Streptozocin co-treated with Dietary Fats] results in increased expression of GPT protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of GPT protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of GPT protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of GPT protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GPT protein]; Metformin inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]		 CTD PMID:11357483 PMID:24854284 PMID:24877639 PMID:26071184 PMID:27350165 More... NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
decreases activity
decreases expression
increases expression		 ISO
EXP		 [Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of GPX1 protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GPX1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX1 mRNA]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of GPX1 protein]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of GPX1 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of GPX1 mRNA; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of GPX1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of GPX1 mRNA; allyl methyl sulfide inhibits the reaction [Streptozocin results in decreased activity of GPX1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; Trientine inhibits the reaction [Streptozocin results in increased expression of GPX1 protein]		 CTD PMID:18789669 PMID:19634143 PMID:23267840 PMID:24740756 PMID:30318971 More... NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions EXP [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in increased expression of GPX2 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in increased expression of GPX2 mRNA; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in increased expression of GPX2 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in increased expression of GPX2 mRNA; [Resveratrol co-treated with Streptozocin] results in increased expression of GPX2 mRNA CTD PMID:25905778 PMID:35786680 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877 		JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of GPX3 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of GPX3 protein]		 CTD PMID:19634143 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX4 mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX4 mRNA] CTD PMID:33359794 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982 		JBrowse link
G Gramd2a GRAM domain containing 2A multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of GRAMD2A mRNA CTD PMID:33484791 NCBI chr 8:60,079,744...60,117,788
Ensembl chr 8:60,080,338...60,115,842 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist increases expression EXP Streptozocin results in increased expression of GREM1 mRNA CTD PMID:10744662 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 multiple interactions
increases expression		 EXP Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIA4 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIA4 protein] CTD PMID:23267840 NCBI chr 8:1,562,118...2,035,035
Ensembl chr 8:1,562,119...2,034,979 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions
increases expression		 EXP Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIN1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIN1 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIN1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIN1 protein]
Streptozocin results in increased expression of GRIN1 mRNA; Streptozocin results in increased expression of GRIN1 protein		 CTD PMID:23267840 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grm5 glutamate metabotropic receptor 5 increases expression EXP Streptozocin results in increased expression of GRM5 protein CTD PMID:19840219 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274 		JBrowse link
G Gsdmd gasdermin D multiple interactions
increases expression
affects response to substance		 ISO
EXP		 [Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD protein; GSDMD protein affects the reaction [Streptozocin results in increased cleavage of CASP1 protein]; GSDMD protein affects the reaction [Streptozocin results in increased expression of IL18 protein]; GSDMD protein affects the reaction [Streptozocin results in increased expression of IL1B protein]; Hirudins inhibits the reaction [Streptozocin results in increased expression of and results in increased cleavage of GSDMD protein]; Hirudins inhibits the reaction [Streptozocin results in increased expression of GSDMD mRNA]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD mRNA]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD protein]; Streptozocin results in increased expression of and results in increased cleavage of GSDMD protein
scutellarin inhibits the reaction [Streptozocin results in increased expression of GSDMD protein]
GSDMD protein affects the susceptibility to Streptozocin		 CTD PMID:34212273 PMID:37081038 PMID:37473909 NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation
multiple interactions
increases expression		 EXP
ISO		 Streptozocin results in decreased phosphorylation of GSK3B protein
5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; [Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of GSK3B protein; [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of GSK3B protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of GSK3B protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of GSK3B protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]
Streptozocin results in increased expression of GSK3B mRNA
[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein; Curcumin inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of GSK3B mRNA]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein]; Streptozocin results in decreased expression of and results in decreased phosphorylation of GSK3B protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of GSK3B protein]; Tribulus extract inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]		 CTD PMID:25541178 PMID:27038876 PMID:28422052 PMID:31877369 PMID:33484791 More... NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gspt2 G1 to S phase transition 2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of GSPT2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GSPT2 mRNA] CTD PMID:33484791 NCBI chr  X:59,587,237...59,589,758
Ensembl chr  X:59,587,276...59,594,162 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases expression
affects activity
increases activity
decreases activity		 EXP [Carmustine results in decreased activity of GSR protein] which results in increased susceptibility to Streptozocin; [Dietary Fats co-treated with Streptozocin] results in decreased activity of GSR protein; [Niacinamide co-treated with Streptozocin] results in decreased activity of GSR protein; [Streptozocin co-treated with Dietary Fats] results in decreased activity of GSR protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of GSR protein; [Zinc Sulfate results in increased abundance of Zinc] inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Bezafibrate inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; caryophyllene inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Chromium inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; chromium tripicolinate inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of GSR protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of GSR protein]; geraniol inhibits the reaction [Streptozocin affects the activity of GSR protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of GSR protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GSR protein]; Glyburide inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of GSR protein]; INS protein promotes the reaction [Streptozocin results in increased activity of GSR protein]; Metformin inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; morin inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of GSR protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of GSR protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GSR protein]; Rosiglitazone inhibits the reaction [Streptozocin promotes the reaction [Dietary Fats results in decreased activity of GSR protein]]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Streptozocin promotes the reaction [Dietary Fats results in decreased activity of GSR protein]; Zinc inhibits the reaction [Streptozocin results in decreased activity of GSR protein] CTD PMID:11424224 PMID:15720826 PMID:17145126 PMID:19682444 PMID:19840221 More... NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions EXP [Streptozocin co-treated with iomeprol] results in increased expression of GSTA1 protein; palmidrol analog inhibits the reaction [[Streptozocin co-treated with iomeprol] results in increased expression of GSTA1 protein] CTD PMID:26474837 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of GSTA2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of GSTA2 protein]		 CTD PMID:19634143 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 multiple interactions
increases expression
decreases expression		 EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of GSTA3 protein]; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of GSTA3 mRNA] CTD PMID:16684804 PMID:19634143 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression EXP Streptozocin results in increased expression of GSTA4 protein CTD PMID:14693714 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 multiple interactions
increases expression		 EXP [resveratrol co-treated with Streptozocin] results in increased expression of GSTA5 mRNA
Streptozocin results in increased expression of GSTA5 mRNA		 CTD PMID:25905778 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of GSTM2 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of GSTM2 mRNA]		 CTD PMID:16684804 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions EXP [Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA] CTD PMID:21439372 NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553 		JBrowse link
G Gstm5l glutathione S-transferase, mu 5-like increases expression
multiple interactions		 EXP Streptozocin results in increased expression of GSTM5 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of GSTM5 mRNA]		 CTD PMID:16684804 NCBI chr 2:195,544,424...195,549,895
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression EXP Streptozocin results in decreased expression of GSTP1 mRNA CTD PMID:25905778 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gucy1b2 guanylate cyclase 1 soluble subunit beta 2 decreases expression EXP Streptozocin results in decreased expression of GUCY1B2 mRNA CTD PMID:25905778 NCBI chr15:36,589,501...36,669,441
Ensembl chr15:36,598,883...36,669,441 		JBrowse link
G Gys1 glycogen synthase 1 decreases expression
increases phosphorylation
multiple interactions		 EXP Streptozocin results in decreased expression of GYS1 mRNA
Streptozocin results in increased phosphorylation of GYS1 protein
Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of GYS1 mRNA]; Tribulus extract inhibits the reaction [Streptozocin results in increased phosphorylation of GYS1 protein]		 CTD PMID:27038876 PMID:36627075 NCBI chr 1:95,915,443...95,935,292
Ensembl chr 1:95,915,443...95,935,292 		JBrowse link
G Gys2 glycogen synthase 2 multiple interactions EXP [Streptozocin co-treated with Niacinamide] affects the activity of GYS2 protein; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] affects the activity of GYS2 protein] CTD PMID:19059388 NCBI chr 4:175,365,054...175,406,228
Ensembl chr 4:175,365,054...175,406,228 		JBrowse link
G H19 H19 imprinted maternally expressed transcript multiple interactions EXP [Resveratrol co-treated with Streptozocin] results in increased expression of H19 mRNA CTD PMID:25905778 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134 		JBrowse link
G H3c1 H3 clustered histone 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of H3C2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of H3C2 mRNA] CTD PMID:33484791 NCBI chr17:41,368,379...41,368,902
Ensembl chr17:41,368,386...41,368,856
Ensembl chr17:41,368,386...41,368,856
Ensembl chr17:41,368,386...41,368,856
Ensembl chr17:41,368,386...41,368,856 		JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions EXP [Streptozocin co-treated with iron pentacarbonyl] results in increased expression of HAMP mRNA CTD PMID:22170771 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Hao2 hydroxyacid oxidase 2 multiple interactions
decreases expression		 EXP [resveratrol co-treated with Streptozocin] results in decreased expression of HAO2 mRNA; Trientine inhibits the reaction [Streptozocin results in decreased expression of HAO2 protein]
Streptozocin results in decreased expression of HAO2 mRNA; Streptozocin results in decreased expression of HAO2 protein		 CTD PMID:19634143 PMID:25905778 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425 		JBrowse link
G Hapln1 hyaluronan and proteoglycan link protein 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of HAPLN1 mRNA CTD PMID:33484791 NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 decreases expression
increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in decreased expression of HAVCR1 mRNA
Streptozocin results in increased expression of HAVCR1 protein
[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]; Metformin promotes the reaction [dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]]; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of HAVCR1 protein]		 CTD PMID:19516248 PMID:30551545 PMID:37224990 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 multiple interactions
increases glycation		 EXP [Streptozocin co-treated with Niacinamide] results in increased glycosylation of HBA1 protein; coumarin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased glycosylation of HBA1 protein]
Streptozocin results in increased glycation of HBA1 protein		 CTD PMID:19647726 PMID:21139377 NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392 		JBrowse link
G Hbb hemoglobin subunit beta decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of HBB-B1 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of HBB-B1 protein]		 CTD PMID:19634143 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of HCK mRNA CTD PMID:25905778 NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693 		JBrowse link
G Hdac3 histone deacetylase 3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of HDAC3 protein; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MIR10A mRNA]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein] CTD PMID:27292126 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856 		JBrowse link
G Hdac5 histone deacetylase 5 multiple interactions EXP [Streptozocin co-treated with Fructose] results in increased expression of HDAC5 protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HDAC5 protein] CTD PMID:34656705 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235 		JBrowse link
G Hesx1 HESX homeobox 1 multiple interactions ISO [Diethylhexyl Phthalate co-treated with Streptozocin co-treated with Dietary Fats] results in decreased expression of HESX1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of HESX1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of HESX1 mRNA] CTD PMID:33484791 NCBI chr16:2,191,852...2,193,957
Ensembl chr16:2,191,852...2,193,957 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of HIF1A protein
Streptozocin results in increased expression of HIF1A mRNA
[Streptozocin co-treated with Dietary Fats] results in increased expression of HIF1A protein; bicalutamide promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of HIF1A protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of HIF1A mRNA]]; Ozone inhibits the reaction [Streptozocin results in increased expression of HIF1A mRNA]		 CTD PMID:26073000 PMID:26614261 PMID:35151640 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hk1 hexokinase 1 decreases activity
multiple interactions		 EXP Streptozocin results in decreased activity of HK1 protein
[homocastasterone analog co-treated with Streptozocin] results in increased expression of HK1 mRNA; plumbagin inhibits the reaction [Streptozocin results in decreased activity of HK1 protein]		 CTD PMID:22960630 PMID:28822685 NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131 		JBrowse link
G Hmgb1 high mobility group box 1 increases expression
multiple interactions		 ISO Streptozocin results in increased expression of HMGB1 mRNA
manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Streptozocin results in increased expression of HMGB1 mRNA]		 CTD PMID:19833897 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases expression		 EXP
ISO		 [Dietary Fats co-treated with Streptozocin] results in increased expression of HMGCR mRNA; [Streptozocin co-treated with Cadmium] results in increased activity of HMGCR protein; [Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein; [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased activity of HMGCR protein]; tetrahydrocurcumin results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HMGCR mRNA]
Streptozocin results in increased expression of HMGCR mRNA
Acrylamide inhibits the reaction [Streptozocin results in increased expression of HMGCR mRNA]		 CTD PMID:20696151 PMID:25240712 PMID:25905778 PMID:27488359 PMID:34896238 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of HMGCS2 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of HMGCS2 mRNA]		 CTD PMID:16684804 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130 		JBrowse link
G Hmox1 heme oxygenase 1 decreases activity
decreases expression
multiple interactions
increases expression		 EXP
ISO		 Streptozocin results in decreased activity of HMOX1 protein
Streptozocin results in decreased expression of HMOX1 mRNA; Streptozocin results in decreased expression of HMOX1 protein
[Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA; [Streptozocin co-treated with sulforaphane] results in increased expression of HMOX1; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]
HMOX1 protein inhibits the reaction [Streptozocin results in decreased expression of SLC25A19 protein]
Streptozocin results in increased expression of HMOX1 mRNA; Streptozocin results in increased expression of HMOX1 protein
[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased activity of HMOX1 protein; [cobaltiprotoporphyrin co-treated with Streptozocin] results in increased expression of HMOX1 protein; [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; [Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein; [Streptozocin co-treated with Hemin] results in increased activity of HMOX1 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of HMOX1 protein; caffeic acid phenethyl ester inhibits the reaction [Streptozocin results in increased expression of HMOX1 protein]; chromium mesoporphyrin inhibits the reaction [[Streptozocin co-treated with Hemin] results in increased activity of HMOX1 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of and results in decreased activity of HMOX1 protein]; cobaltiprotoporphyrin promotes the reaction [Streptozocin results in increased expression of HMOX1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of HMOX1 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA]; palbinone inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; Propofol inhibits the reaction [Streptozocin results in decreased activity of HMOX1 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of HMOX1 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; Streptozocin results in decreased expression of and results in decreased activity of HMOX1 protein; Streptozocin results in increased expression of and results in decreased activity of HMOX1 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; tin mesoporphyrin inhibits the reaction [[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased activity of HMOX1 protein]; tin mesoporphyrin inhibits the reaction [[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased expression of HMOX1 protein]		 CTD PMID:16309587 PMID:16595661 PMID:19019021 PMID:19190261 PMID:21439372 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hmox2 heme oxygenase 2 multiple interactions
increases response to substance		 ISO cobaltiprotoporphyrin inhibits the reaction [HMOX2 gene mutant form results in increased susceptibility to Streptozocin]; tin mesoporphyrin promotes the reaction [HMOX2 gene mutant form results in increased susceptibility to Streptozocin] CTD PMID:16524951 NCBI chr10:10,797,076...10,831,178
Ensembl chr10:10,797,055...10,831,148 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha increases expression
multiple interactions		 ISO Streptozocin results in increased expression of HNF4A mRNA
Acrylamide inhibits the reaction [Streptozocin results in increased expression of HNF4A mRNA]		 CTD PMID:34896238 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G Hopx HOP homeobox multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of HOPX mRNA CTD PMID:25905778 NCBI chr14:31,055,912...31,082,909
Ensembl chr14:31,075,148...31,082,909 		JBrowse link
G Hp haptoglobin multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of HP mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of HP mRNA] CTD PMID:33484791 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Hras HRas proto-oncogene, GTPase decreases farnesylation EXP Streptozocin results in decreased farnesylation of HRAS protein CTD PMID:19002579 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of HSD17B10 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of HSD17B10 protein]		 CTD PMID:21136691 NCBI chr  X:21,089,142...21,091,603
Ensembl chr  X:21,089,122...21,109,488 		JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of HSD17B2 mRNA CTD PMID:25905778 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects expression ISO Streptozocin affects the expression of HSD17B4 mRNA CTD PMID:18583417 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952 		JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 affects expression ISO Streptozocin affects the expression of HSD3B3 mRNA CTD PMID:18583417 NCBI chr 2:186,138,044...186,144,024
Ensembl chr 2:186,138,044...186,144,033 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP Streptozocin results in increased expression of HSP90AA1 mRNA CTD PMID:37081038 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions
increases expression 		ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of HSP90B1 mRNA
streptozocin increases expression of Hsp90b1 protein in heart		 CTD
RGD		 PMID:26522834 PMID:36044268 RGD:156430337 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 affects expression ISO Streptozocin affects the expression of HSPA2 mRNA CTD PMID:18583417 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
decreases expression		 EXP
ISO		 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of HSPA5 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of HSPA5 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of HSPA5 mRNA; Bilirubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of HSPA5 mRNA]; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of HSPA5 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of HSPA5 protein]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of HSPA5 protein]; Streptozocin results in increased expression of and results in increased secretion of HSPA5 protein; Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPA5 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased expression of HSPA5 protein]
streptozocin increases expression of Hspa5 protein in heart
[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 protein; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of HSPA5 mRNA]; [Streptozocin co-treated with Dietary Fats] results in increased expression of HSPA5 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of HSPA5 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of HSPA5 protein]		 CTD
RGD		 PMID:19634143 PMID:24967692 PMID:26522834 PMID:27664441 PMID:30980806 More... RGD:156430337 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of HSPA9 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPA9 protein]		 CTD PMID:19634143 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions
increases phosphorylation		 EXP baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of HSPB1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of HSPB1 protein] CTD PMID:18204486 PMID:34414639 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions
decreases expression
increases expression		 EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPD1 protein]; Trientine inhibits the reaction [Streptozocin results in increased expression of HSPD1 protein] CTD PMID:19634143 PMID:21136691 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 multiple interactions
decreases expression		 EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPE1 protein] CTD PMID:19634143 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089 		JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of HSPG2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of HSPG2 protein]		 CTD PMID:19634143 NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP Streptozocin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased activity of HTR1A protein] CTD PMID:18622176 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions EXP Streptozocin inhibits the reaction [4-iodo-2,5-dimethoxyphenylisopropylamine results in increased activity of HTR2A protein] CTD PMID:18622176 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of HTR2C mRNA CTD PMID:33484791 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Iapp islet amyloid polypeptide multiple interactions
decreases expression		 EXP
ISO		 rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of IAPP mRNA]
[octylphenol co-treated with Streptozocin] results in decreased expression of IAPP mRNA; Streptozocin inhibits the reaction [Ethinyl Estradiol results in decreased expression of IAPP mRNA]		 CTD PMID:18998217 PMID:29935216 NCBI chr 4:175,237,107...175,244,373
Ensembl chr 4:175,237,115...175,242,920 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression		 ISO
EXP		 AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]]; Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; dehydroxymethylepoxyquinomicin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; dehydroxymethylepoxyquinomicin inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]
Streptozocin results in increased expression of ICAM1 mRNA; Streptozocin results in increased expression of ICAM1 protein
[Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of ICAM1 protein; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; candesartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; cloricromen inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of ICAM1 protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]		 CTD PMID:10485912 PMID:14871415 PMID:15892581 PMID:16129698 PMID:16139267 More... NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression EXP Streptozocin results in decreased expression of ID2 mRNA CTD PMID:25905778 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 affects expression ISO Streptozocin affects the expression of IDH2 mRNA CTD PMID:18583417 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of IFITM3 mRNA CTD PMID:25905778 NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203 		JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
increases expression		 ISO
EXP		 Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of IFNG protein]; Dronabinol inhibits the reaction [Streptozocin results in increased expression of IFNG mRNA]; S-Nitroso-N-Acetylpenicillamine inhibits the reaction [Streptozocin results in increased expression of IFNG protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of IFNG mRNA]
Streptozocin results in decreased expression of IFNG protein
arjunolic acid inhibits the reaction [Streptozocin results in decreased expression of IFNG protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of IFNG protein]
Streptozocin results in increased expression of IFNG mRNA; Streptozocin results in increased expression of IFNG protein		 CTD PMID:11357882 PMID:15862027 PMID:15892581 PMID:15975818 PMID:18789669 More... NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igdcc4 immunoglobulin superfamily, DCC subclass, member 4 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of IGDCC4 mRNA CTD PMID:33484791 NCBI chr 8:65,621,893...65,657,651
Ensembl chr 8:65,621,897...65,657,648 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
decreases expression
increases expression		 ISO
EXP		 [Dietary Fats co-treated with Streptozocin] results in increased expression of IGF1 mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IGF1 mRNA]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of AGT protein]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]; puerarin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]
[Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]]
Streptozocin results in increased expression of IGF1 protein
Streptozocin results in decreased expression of IGF1 mRNA; Streptozocin results in decreased expression of IGF1 protein		 CTD PMID:7637645 PMID:9868179 PMID:11375343 PMID:23927877 PMID:25617479 More... NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in decreased expression of IGF1R protein
[Streptozocin co-treated with CNR1 protein] affects the expression of IGF1R protein
[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R protein; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R mRNA]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased expression of IGF1R protein]		 CTD PMID:23562514 PMID:30721768 PMID:36547818 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of IGF2BP3 mRNA CTD PMID:25905778 NCBI chr 4:78,060,494...78,195,007
Ensembl chr 4:78,060,494...78,194,865 		JBrowse link
G Igf2r insulin-like growth factor 2 receptor increases expression
increases response to substance
multiple interactions		 EXP Streptozocin results in increased expression of IGF2R protein
IGF2R protein alternative form results in increased susceptibility to Streptozocin
[IGF2R protein alternative form results in increased susceptibility to Streptozocin] which results in increased abundance of Cholesterol; [IGF2R protein alternative form results in increased susceptibility to Streptozocin] which results in increased abundance of Triglycerides; [Streptozocin co-treated with IGF2R protein modified form] results in increased expression of CASP3 protein modified form; IGF2R protein modified form inhibits the reaction [Streptozocin results in increased expression of CASP9 protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in decreased expression of NFKBIA protein modified form]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of IL1B protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of PTGS2 protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of RELA protein modified form]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of TNF protein]; Streptozocin promotes the reaction [IGF2R protein alternative form results in increased abundance of Triglycerides]; Streptozocin promotes the reaction [IGF2R protein modified form results in decreased expression of BCL2 protein modified form]; Streptozocin promotes the reaction [IGF2R protein modified form results in decreased expression of NFKBIA protein modified form]; Streptozocin promotes the reaction [IGF2R protein modified form results in increased expression of IL6 protein]; Streptozocin promotes the reaction [IGF2R protein modified form results in increased expression of RELA protein modified form]		 CTD PMID:35993117 PMID:36462176 NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501 		JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of IGFBP2 mRNA CTD PMID:25905778 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 multiple interactions
increases expression		 ISO 2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of IGFBP3 mRNA] CTD PMID:29673160 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 increases expression ISO Streptozocin results in increased expression of IGFBP7 mRNA CTD PMID:29673160 NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314 		JBrowse link
G Igsf6 immunoglobulin superfamily, member 6 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of IGSF6 mRNA CTD PMID:25905778 NCBI chr 1:175,610,167...175,620,662
Ensembl chr 1:175,610,167...175,620,722 		JBrowse link
G Il10 interleukin 10 decreases expression
multiple interactions
increases expression		 ISO
EXP		 Streptozocin results in decreased expression of IL10 mRNA
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 mRNA]; 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 protein]; [Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 mRNA; [Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 protein; Chlorpyrifos inhibits the reaction [Streptozocin results in increased expression of IL10 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 protein]
Streptozocin results in decreased expression of IL10 mRNA; Streptozocin results in decreased expression of IL10 protein
[Streptozocin co-treated with Dietary Fats] results in decreased expression of IL10 protein; [Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of IL10 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of IL10 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]		 CTD PMID:15862027 PMID:32662907 PMID:33524429 PMID:33639173 PMID:35085591 More... NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il12b interleukin 12B increases expression
multiple interactions		 ISO Streptozocin results in increased expression of IL12B mRNA
Dronabinol inhibits the reaction [Streptozocin results in increased expression of IL12B mRNA]		 CTD PMID:11357882 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il17a interleukin 17A multiple interactions
increases expression		 EXP stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased expression of IL17A protein]] CTD PMID:23611540 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il18 interleukin 18 multiple interactions
increases expression		 EXP
ISO		 [Streptozocin co-treated with Niacinamide co-treated with ENV-2 compound] results in decreased expression of IL18 mRNA; Allopurinol inhibits the reaction [Streptozocin results in increased expression of IL18 protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased expression of IL18 mRNA]; palbinone inhibits the reaction [Streptozocin results in increased expression of IL18 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of IL18 protein]; scutellarin inhibits the reaction [Streptozocin results in increased expression of IL18 protein]
[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL18 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL18 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL18 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL18 protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL18 protein]; GSDMD protein affects the reaction [Streptozocin results in increased expression of IL18 protein]; Hirudins inhibits the reaction [Streptozocin results in increased expression of IL18 protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL18 protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL18 mRNA]
Streptozocin results in increased expression of IL18 mRNA; Streptozocin results in increased expression of IL18 protein		 CTD PMID:23647015 PMID:28322830 PMID:29291386 PMID:32202043 PMID:34212273 More... NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [Streptozocin co-treated with bisphenol A] results in increased expression of IL1A mRNA; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of IL1A mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of IL1A mRNA CTD PMID:24781736 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
decreases expression		 ISO
EXP		 PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]
Streptozocin results in increased expression of IL1B mRNA; Streptozocin results in increased expression of IL1B protein
Streptozocin results in decreased expression of IL1B protein
7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein]; [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of IL1B protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein; [Niacinamide co-treated with Streptozocin] results in increased expression of IL1B protein; [pimagedine co-treated with Fatty Acids, Omega-3] inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of IL1B protein]; [Resveratrol co-treated with Streptozocin] results in increased expression of IL1B mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein; [Streptozocin co-treated with Niacinamide co-treated with ENV-2 compound] results in decreased expression of IL1B mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of IL1B protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of IL1B protein]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of IL1B protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL1B protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL1B protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of IL1B protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of IL1B protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of IL1B protein]]; myrtenol inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; palbinone inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; pinitol inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL1B protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL1B protein]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL1B mRNA]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL1B protein]; Streptozocin results in increased expression of and results in increased secretion of IL1B protein; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of IL1B protein]; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of IL1B protein]
[Chlorpyrifos co-treated with Streptozocin] results in increased expression of IL1B mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL1B protein; [Streptozocin co-treated with Dextran Sulfate] results in increased expression of IL1B protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of IL1B protein; Acrylamide inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Alendronate inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; asiatic acid inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Streptozocin results in increased expression of IL1B protein]]; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B mRNA]; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of IL1B protein]; Carnosine inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Donepezil inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Genistein inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; GSDMD protein affects the reaction [Streptozocin results in increased expression of IL1B protein]; Hirudins inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL1B protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]		 CTD PMID:12123627 PMID:16129698 PMID:17167242 PMID:17589825 PMID:18789669 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL1RL1 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL1RL1 mRNA CTD PMID:31726037 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256 		JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of IL1RN mRNA CTD PMID:29127188 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il2 interleukin 2 multiple interactions
decreases expression		 EXP arjunolic acid inhibits the reaction [Streptozocin results in decreased expression of IL2 protein] CTD PMID:20053369 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il23a interleukin 23 subunit alpha increases expression
multiple interactions		 ISO Streptozocin results in increased expression of IL23A protein
5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of IL23A protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of IL23A protein]		 CTD PMID:34428446 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il27 interleukin 27 multiple interactions
increases expression		 ISO 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of IL27 protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of IL27 protein] CTD PMID:34428446 NCBI chr 1:181,173,108...181,178,720
Ensembl chr 1:181,173,372...181,178,582 		JBrowse link
G Il33 interleukin 33 multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 mRNA]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 protein CTD PMID:31726037 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Il4 interleukin 4 multiple interactions
decreases expression		 EXP resveratrol inhibits the reaction [Streptozocin results in decreased expression of IL4] CTD PMID:25191525 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 increases expression
decreases expression
multiple interactions
increases secretion		 EXP
ISO		 Streptozocin results in increased expression of IL6 mRNA; Streptozocin results in increased expression of IL6 protein
Streptozocin results in decreased expression of IL6 protein
3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL6 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein; [Streptozocin co-treated with Dextran Sulfate] results in increased expression of IL6 protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of IL6 protein; Acrylamide inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Alendronate inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; asiatic acid inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Streptozocin results in increased expression of IL6 protein]]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of IL6 protein]; Carnosine inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Carnosine promotes the reaction [asiatic acid inhibits the reaction [Streptozocin results in increased expression of IL6 protein]]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Donepezil inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 mRNA]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL6 protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of IL6 protein]
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; 4-methyl-2-((2-methylbenzyl) amino)-1,3-thiazole-5-carboxylic acid inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; [Dietary Fats co-treated with Streptozocin co-treated with Plant Extracts] affects the expression of IL6 protein; [Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of IL6 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of IL6 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein; [Niacinamide co-treated with Streptozocin] results in increased expression of IL6 protein; [Propolis co-treated with Streptozocin co-treated with Chlorpyrifos] results in increased secretion of IL6 protein; [Propolis co-treated with Streptozocin] results in increased secretion of IL6 protein; [Streptozocin co-treated with Chlorpyrifos] results in increased secretion of IL6 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of IL6 protein; Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; caryophyllene inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Dronabinol inhibits the reaction [Streptozocin results in decreased expression of IL6 protein]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Flavonoids inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL6 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL6 protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; mangiferin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Melatonin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of IL6 protein]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; pinitol inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in increased secretion of IL6 protein]; Propolis inhibits the reaction [Streptozocin results in increased secretion of IL6 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL6 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL6 protein]; SMe1EC2 promotes the reaction [Streptozocin results in increased expression of IL6 protein]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL6 mRNA]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL6 protein]; Streptozocin promotes the reaction [IGF2R protein modified form results in increased expression of IL6 protein]; Streptozocin results in increased expression of and results in increased secretion of IL6 protein		 CTD PMID:17167242 PMID:17854708 PMID:18999900 PMID:20307516 PMID:20643114 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer affects expression ISO Streptozocin affects the expression of IL6ST mRNA CTD PMID:26073000 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Ilk integrin-linked kinase multiple interactions
increases activity		 EXP notoginsenoside R1 inhibits the reaction [Streptozocin results in increased activity of ILK protein] CTD PMID:25503068 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140 		JBrowse link
G Impa2 inositol monophosphatase 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of IMPA2 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of IMPA2 mRNA]		 CTD PMID:16684804 NCBI chr18:60,834,206...60,867,575
Ensembl chr18:60,834,246...60,865,641 		JBrowse link
G Inava innate immunity activator multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of INAVA mRNA CTD PMID:33484791 NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729 		JBrowse link
G Inhbb inhibin subunit beta B multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of INHBB mRNA CTD PMID:29127188 NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832 		JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of INPP5K mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of INPP5K mRNA] CTD PMID:33812996 NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773 		JBrowse link
G Ins1 insulin 1 decreases secretion
multiple interactions
decreases expression
decreases response to substance
increases expression
increases secretion		 EXP
ISO		 Streptozocin results in decreased secretion of INS1 protein
4-hydroxyisoleucine inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; 4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; 4-methyl-2-((2-methylbenzyl) amino)-1,3-thiazole-5-carboxylic acid inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein; [Dietary Fats co-treated with Streptozocin] results in decreased secretion of INS1 protein; [Dietary Fats co-treated with Streptozocin] results in increased secretion of INS1 protein; [INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]; [INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in increased expression of ACE protein]; [Niacinamide co-treated with Streptozocin] results in decreased expression of INS1 protein; [Plant Extracts co-treated with glimepiride] inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; [Propolis co-treated with Chlorpyrifos] inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; [Propolis co-treated with Streptozocin co-treated with Chlorpyrifos] results in decreased secretion of INS1 protein; [Propolis co-treated with Streptozocin] promotes the reaction [Chlorpyrifos results in decreased expression of INS1 protein]; [Propolis co-treated with Streptozocin] promotes the reaction [Chlorpyrifos results in decreased secretion of INS1 protein]; [Propolis co-treated with Streptozocin] results in decreased secretion of INS1 protein; [Streptozocin co-treated with Cadmium] results in decreased expression of INS1 protein; [Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in increased expression of INS1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein; [Streptozocin co-treated with Fructose] results in increased expression of INS1 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of INS1 protein; [Streptozocin co-treated with Niacinamide] results in decreased secretion of INS1 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of INS1 protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of INS1 protein]; allyl isothiocyanate inhibits the reaction [Streptozocin promotes the reaction [Dietary Fats results in increased expression of INS1 protein]]; anthranilic acid analog inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; baicalin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Butyric Acid inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; caryophyllene inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; chebulagic acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein]; Chlorpyrifos inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; citronellol inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; corilagin inhibits the reaction [Streptozocin results in increased secretion of INS1 protein]; costunolide inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; coumarin inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased expression of INS1 protein]; coumarin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of INS1 protein]; crocin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Diosgenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein]; Diosgenin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Estradiol inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of INS1 protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]; geraniol inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; glimepiride inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased secretion of INS1 protein]; Imatinib Mesylate inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GAD1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased activity of CAT protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CASP8 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of COL3A1 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CYP8B1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIA4 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIN1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIN1 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of MMP2 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of MMP9 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; Lithium Carbonate inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; mangiferin inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; Melatonin affects the reaction [Streptozocin results in decreased expression of INS1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in increased expression of INS1 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein]; morin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of INS1 protein]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; palbinone inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of INS1 protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in increased expression of INS1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; plumbagin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Polysaccharides inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in decreased secretion of INS1 protein]; Propolis inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of INS1 protein]; repaglinide analog affects the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; repaglinide inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of INS1 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Rosiglitazone promotes the reaction [Streptozocin inhibits the reaction [Dietary Fats results in increased expression of INS1 protein]]; S-allylcysteine inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Streptozocin affects the reaction [Chlorpyrifos results in decreased secretion of INS1 protein]; Streptozocin inhibits the reaction [Blood Glucose results in increased secretion of INS1 protein]; Streptozocin inhibits the reaction [Dietary Fats results in increased expression of INS1 protein]; Streptozocin promotes the reaction [Dietary Fats results in increased expression of INS1 protein]; Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein; thymoquinone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of INS1 protein]; thymoquinone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased secretion of INS1 protein]; TRH protein inhibits the reaction [Streptozocin inhibits the reaction [Blood Glucose results in increased secretion of INS1 protein]]; Tribulus extract inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased secretion of INS1 protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein]
ALPK1 protein promotes the reaction [Streptozocin results in decreased secretion of INS1 protein]
Streptozocin results in decreased expression of INS1; Streptozocin results in decreased expression of INS1 protein
Streptozocin results in decreased expression of INS1 protein; Streptozocin results in decreased expression of INS1 protein modified form
Streptozocin results in decreased susceptibility to INS1 protein
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of INS1 protein]; [Carnosine co-treated with asiatic acid] inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of INS1 protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of INS1 protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of INS1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein; [Streptozocin co-treated with INS1 protein co-treated with Glutathione] affects the expression of CAT mRNA; [Streptozocin co-treated with INS1 protein co-treated with Glutathione] affects the expression of SOD2 mRNA; AM 251 inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; bisphenol A inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Carnosine inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of INS1 protein]; Dronabinol inhibits the reaction [Streptozocin results in decreased expression of INS1]; Edaravone inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Ethinyl Estradiol inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of INS1 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine]; INS1 protein affects the reaction [Streptozocin results in decreased methylation of PPP2CA protein]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of POU1F1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of POU1F1 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of SLC20A2 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of SLC20A2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; octylphenol inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; PQQ Cofactor inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; pterostilbene inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]; Streptozocin inhibits the reaction [Glucose results in increased secretion of INS1 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]
Streptozocin results in increased expression of INS1 mRNA; Streptozocin results in increased expression of INS1 protein		 CTD PMID:6337899 PMID:7564366 PMID:9868179 PMID:10393316 PMID:10700396 More... NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Ins2 insulin 2 multiple interactions
decreases expression		 ISO
EXP		 INS protein inhibits the reaction [Streptozocin results in decreased expression of NES mRNA]; Resveratrol inhibits the reaction [Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]]; Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]
INS protein inhibits the reaction [Streptozocin results in decreased expression of FASN mRNA]; INS protein inhibits the reaction [Streptozocin results in decreased expression of POMC mRNA]; INS protein inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; INS protein inhibits the reaction [Streptozocin results in increased expression of AGRP mRNA]; INS protein inhibits the reaction [Streptozocin results in increased expression of NPY mRNA]; INS protein promotes the reaction [Streptozocin results in decreased activity of SOD2 protein]; INS protein promotes the reaction [Streptozocin results in increased activity of GSR protein]; INS protein promotes the reaction [Streptozocin results in increased expression of PPARG mRNA]
Streptozocin results in decreased expression of INS protein
[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS2 mRNA; [Diethylhexyl Phthalate co-treated with Streptozocin co-treated with Dietary Fats] results in increased expression of INS2 mRNA; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of INS2 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of INS2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS2 mRNA]; INS protein inhibits the reaction [Streptozocin results in decreased activity of SOD3 protein]; INS protein inhibits the reaction [Streptozocin results in decreased expression of ATP7A protein]		 CTD PMID:11216864 PMID:19388005 PMID:20219977 PMID:22940631 PMID:23884884 More... NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Insig1 insulin induced gene 1 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of INSIG1 mRNA CTD PMID:33359794 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Insig2 insulin induced gene 2 decreases expression EXP Streptozocin results in decreased expression of INSIG2 mRNA CTD PMID:25905778 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923 		JBrowse link
G Insr insulin receptor affects expression
increases expression
multiple interactions
decreases expression
decreases phosphorylation		 EXP
ISO		 Streptozocin affects the expression of INSR protein
streptozocin increases expression of hepatic mRNA
[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of INSR mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of INSR protein; [Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of INSR mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of INSR protein; Estradiol affects the reaction [Streptozocin affects the expression of INSR protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of INSR protein]; Melatonin inhibits the reaction [Streptozocin results in decreased expression of INSR protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of INSR mRNA]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of INSR protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR mRNA]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR protein]; Progesterone affects the reaction [Streptozocin affects the expression of INSR protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of INSR protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA]]; xanthoceraside inhibits the reaction [Streptozocin results in decreased expression of INSR protein]
resveratrol inhibits the reaction [Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]]; Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of INSR protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of INSR protein; [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of INSR protein; Metformin inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA]; puerarin inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA]
Streptozocin results in increased expression of INSR mRNA
Streptozocin results in decreased phosphorylation of INSR protein
Streptozocin results in decreased expression of INSR mRNA; Streptozocin results in decreased expression of INSR protein		 CTD
RGD		 PMID:9243097 PMID:17068109 PMID:18331706 PMID:19705549 PMID:21439094 More... RGD:15036814 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Insrr insulin receptor-related receptor multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of INSRR mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INSRR mRNA] CTD PMID:33359794 NCBI chr 2:173,255,335...173,274,800
Ensembl chr 2:173,255,414...173,274,800 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 multiple interactions
increases expression		 EXP Glyburide inhibits the reaction [Streptozocin results in increased expression of IRAK1 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of IRAK1 protein] CTD PMID:36504472 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of IRF1 mRNA CTD PMID:25905778 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Irf2 interferon regulatory factor 2 increases expression
multiple interactions		 ISO Streptozocin results in increased expression of IRF2 mRNA
Hirudins inhibits the reaction [Streptozocin results in increased expression of IRF2 mRNA]		 CTD PMID:34212273 NCBI chr16:45,439,215...45,550,054
Ensembl chr16:45,439,225...45,550,024 		JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions
decreases phosphorylation
decreases expression		 ISO
EXP		 [Dietary Fats co-treated with Streptozocin] results in decreased expression of IRS1 mRNA; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of IRS1 protein; [Streptozocin co-treated with Dietary Fats] affects the phosphorylation of IRS1 protein; [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of IRS1 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of IRS1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of IRS1 mRNA]; Metformin inhibits the reaction [Streptozocin results in decreased expression of IRS1 protein]; Metformin promotes the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of IRS1 protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of IRS1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] affects the phosphorylation of IRS1 protein]
Streptozocin results in decreased phosphorylation of IRS1 protein
Streptozocin results in decreased expression of IRS1 mRNA; Streptozocin results in decreased expression of IRS1 protein
[Streptozocin co-treated with Cadmium] results in decreased expression of IRS1 protein; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of IRS1 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased phosphorylation of IRS1 protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of IRS1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of IRS1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of IRS1 protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of IRS1 mRNA]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of IRS1 mRNA]]		 CTD PMID:23927877 PMID:24923654 PMID:26071184 PMID:26522834 PMID:31743741 More... NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions
decreases expression		 EXP
ISO		 [Streptozocin co-treated with Cadmium] results in decreased expression of IRS2 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of IRS2 protein; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IRS2 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of IRS2 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of IRS2 protein]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of IRS2 protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of IRS2 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IRS2 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of IRS2 mRNA]
[Streptozocin co-treated with bisphenol A] results in decreased expression of IRS2 mRNA; [Streptozocin co-treated with octylphenol] results in decreased expression of IRS2 mRNA
Streptozocin results in decreased expression of IRS2 mRNA; Streptozocin results in decreased expression of IRS2 protein		 CTD PMID:24923654 PMID:26071184 PMID:27417257 PMID:29935216 PMID:33724628 More... NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482 		JBrowse link
G Isyna1 inositol-3-phosphate synthase 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ISYNA1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ISYNA1 mRNA] CTD PMID:33484791 NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979 		JBrowse link
G Itga3 integrin subunit alpha 3 multiple interactions
decreases expression		 ISO
EXP		 notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGA3 mRNA]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGA3 protein]
Streptozocin results in decreased expression of ITGA3 mRNA; Streptozocin results in decreased expression of ITGA3 protein		 CTD PMID:25503068 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118 		JBrowse link
G Itgal integrin subunit alpha L multiple interactions
increases expression		 EXP [resveratrol co-treated with Streptozocin] results in increased expression of ITGAL mRNA; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGAL protein] CTD PMID:16129698 PMID:25905778 NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732 		JBrowse link
G Itgam integrin subunit alpha M multiple interactions
increases expression		 EXP Ibuprofen inhibits the reaction [Streptozocin results in increased expression of ITGAM mRNA]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of ITGAM protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGAM protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of ITGAM mRNA]; Memantine inhibits the reaction [Streptozocin results in increased expression of ITGAM protein]
Streptozocin results in increased expression of ITGAM mRNA; Streptozocin results in increased expression of ITGAM protein		 CTD PMID:16129698 PMID:24333387 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Itgav integrin subunit alpha V affects expression ISO Streptozocin affects the expression of ITGAV mRNA CTD PMID:26073000 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in decreased expression of ITGB1 mRNA; Streptozocin results in decreased expression of ITGB1 protein
notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGB1 mRNA]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGB1 protein]		 CTD PMID:25503068 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Itgb2 integrin subunit beta 2 multiple interactions
increases expression		 EXP [resveratrol co-treated with Streptozocin] results in increased expression of ITGB2 mRNA; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGB2 protein] CTD PMID:16129698 PMID:25905778 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Itpr3 inositol 1,4,5-trisphosphate receptor, type 3 increases expression
multiple interactions		 ISO Streptozocin results in increased expression of ITPR3 mRNA
[bisphenol A co-treated with Streptozocin] results in increased expression of ITPR3 mRNA; [octylphenol co-treated with Streptozocin] results in increased expression of ITPR3 mRNA		 CTD PMID:29935216 NCBI chr20:5,136,968...5,202,339
Ensembl chr20:5,136,441...5,202,337 		JBrowse link
G Jak2 Janus kinase 2 multiple interactions
increases expression		 EXP 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of JAK2 mRNA]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of JAK2 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of JAK2 protein; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of JAK2 protein]
Streptozocin results in increased expression of JAK2 mRNA; Streptozocin results in increased expression of JAK2 protein		 CTD PMID:34391751 PMID:36650709 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 EXP
ISO		 resveratrol inhibits the reaction [Streptozocin results in increased expression of JUN protein]
Streptozocin results in increased expression of JUN mRNA; Streptozocin results in increased expression of JUN protein
formononetin inhibits the reaction [Streptozocin results in increased expression of JUN mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of JUN protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of JUN mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to MMP9 promoter]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to PARP1 protein]]; Streptozocin promotes the reaction [JUN protein binds to MMP9 promoter]; Streptozocin promotes the reaction [JUN protein binds to PARP1 protein]		 CTD PMID:26499206 PMID:28478229 PMID:30642005 PMID:35315182 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcnab3 potassium voltage-gated channel subfamily A regulatory beta subunit 3 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of KCNAB3 mRNA; ginsenoside Rh4 affects the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of KCNAB3 mRNA] CTD PMID:33359794 NCBI chr10:54,047,830...54,056,401
Ensembl chr10:54,047,825...54,054,174 		JBrowse link
G Kcnh1 potassium voltage-gated channel subfamily H member 1 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of KCNH1 mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of KCNH1 mRNA] CTD PMID:33359794 NCBI chr13:103,722,140...104,024,762
Ensembl chr13:103,722,245...104,024,740 		JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 increases expression ISO Streptozocin results in increased expression of KCNN2 protein CTD PMID:30635400 NCBI chr18:37,817,966...38,258,347
Ensembl chr18:37,817,957...38,258,347 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 increases expression
multiple interactions		 EXP
ISO		 Streptozocin increases expression of Kcnn4 mRNA and protein in thoracic aorta smooth muscle tissue
streptozocin cotreated with high fat diet increases expression of Kcnn4 protein in aorta
exendin-4 inhibits the reaction [Streptozocin increases expression of Kcnn4 mRNA and protein in thoracic aorta smooth muscle tissue] 		RGD PMID:29167619 PMID:35149165 PMID:29167619 RGD:401784495, RGD:401784497, RGD:401784495 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340 		JBrowse link
G Kcnt1 potassium sodium-activated channel subfamily T member 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of KCNT1 mRNA CTD PMID:33484791 NCBI chr 3:8,682,964...8,736,615
Ensembl chr 3:8,682,113...8,736,667 		JBrowse link
G Kdr kinase insert domain receptor multiple interactions
increases expression		 EXP
ISO		 Simvastatin inhibits the reaction [Streptozocin results in increased expression of KDR mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased expression of KDR protein]; Streptozocin results in increased phosphorylation of and results in increased expression of KDR protein
[Dietary Fats co-treated with Streptozocin] results in increased expression of KDR protein; Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of KDR protein]; sarpogrelate inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of KDR protein]
Streptozocin results in increased expression of KDR mRNA; Streptozocin results in increased expression of KDR protein		 CTD PMID:15643138 PMID:20821229 PMID:27097221 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions
increases expression
decreases expression		 EXP
ISO		 [Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 protein; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 protein]; rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein]
2,5-dihydroxybenzoic acid promotes the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of KEAP1 mRNA]; [Streptozocin co-treated with Niacinamide] results in decreased expression of KEAP1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; Metformin promotes the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of KEAP1 mRNA]
Streptozocin results in increased expression of KEAP1 mRNA; Streptozocin results in increased expression of KEAP1 protein		 CTD PMID:21439372 PMID:30817903 PMID:32662907 PMID:33639173 PMID:34896238 More... NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Kel Kell metallo-endopeptidase (Kell blood group) multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of KEL mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of KEL mRNA] CTD PMID:33484791 NCBI chr 4:70,568,241...70,585,666
Ensembl chr 4:70,568,243...70,585,631 		JBrowse link
G Kl Klotho decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of KL
rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of KL]		 CTD PMID:24136780 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080 		JBrowse link
G Klf15 KLF transcription factor 15 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] promotes the reaction [KLF15 gene mutant form results in increased expression of CCN2 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of KLF15 protein; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of KLF15 protein]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; KLF15 gene mutant form results in increased susceptibility to [Dietary Fats co-treated with Streptozocin] CTD PMID:34310909 NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374 		JBrowse link
G Klf4 KLF transcription factor 4 multiple interactions EXP [Resveratrol co-treated with Streptozocin] results in increased expression of KLF4 mRNA; [Streptozocin co-treated with Niacinamide] promotes the reaction [Dronabinol results in increased expression of KLF4 mRNA] CTD PMID:25905778 PMID:31081965 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Klk1 kallikrein 1 multiple interactions
increases expression		 EXP
ISO		 KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGAL protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGAM protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGB2 protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of TNF protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein]
Streptozocin results in increased expression of KLK1 mRNA		 CTD PMID:16129698 PMID:19516248 NCBI chr 1:94,642,644...94,646,760
Ensembl chr 1:94,642,687...94,646,754 		JBrowse link
G Kng1 kininogen 1 multiple interactions
increases response to substance		 EXP Streptozocin promotes the reaction [KNG1 protein modified form results in increased secretion of Dinoprostone]; Streptozocin promotes the reaction [KNG1 protein modified form results in increased secretion of TAC1 protein modified form]
Streptozocin results in increased susceptibility to KNG1 protein modified form		 CTD PMID:20832942 NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555 		JBrowse link
G Krt19 keratin 19 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of KRT19 mRNA CTD PMID:25905778 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Kynu kynureninase multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of KYNU mRNA CTD PMID:25905778 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
G Lama1 laminin subunit alpha 1 multiple interactions ISO [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of LAMA1 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of LAMA1 protein CTD PMID:38282657 NCBI chr 9:107,692,770...107,816,847
Ensembl chr 9:107,692,770...107,817,478 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions EXP [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of LAMP1 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of LAMP1 mRNA; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of LAMP1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of LAMP1 mRNA CTD PMID:35786680 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883 		JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 multiple interactions EXP [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of LAMP2 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of LAMP2 mRNA; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of LAMP2 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of LAMP2 mRNA CTD PMID:35786680 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522 		JBrowse link
G Lap3 leucine aminopeptidase 3 affects expression ISO Streptozocin affects the expression of LAP3 mRNA CTD PMID:18583417 NCBI chr14:65,608,375...65,627,359
Ensembl chr14:65,608,376...65,627,359 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of LAPTM5 mRNA CTD PMID:25905778 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Lcat lecithin cholesterol acyltransferase multiple interactions EXP
ISO		 [Streptozocin co-treated with Cadmium] results in decreased activity of LCAT protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein; [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of LCAT protein]; tetrahydrocurcumin results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein]
[Streptozocin co-treated with Dietary Fats] results in decreased expression of LCAT protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of LCAT protein]		 CTD PMID:20696151 PMID:25240712 PMID:33484791 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231 		JBrowse link
G Lcn2 lipocalin 2 multiple interactions EXP
ISO		 [Resveratrol co-treated with Streptozocin] results in increased expression of LCN2 mRNA; [Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein; [Streptozocin co-treated with iomeprol] results in increased expression of LCN2 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein]; palmidrol analog inhibits the reaction [[Streptozocin co-treated with iomeprol] results in increased expression of LCN2 protein]
[Streptozocin co-treated with Dietary Fats] results in increased expression of LCN2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of LCN2 mRNA]		 CTD PMID:25905778 PMID:26474837 PMID:30551545 PMID:33484791 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Ldhb lactate dehydrogenase B increases expression
multiple interactions		 EXP Streptozocin results in increased expression of LDHB protein
Trientine inhibits the reaction [Streptozocin results in increased expression of LDHB protein]		 CTD PMID:19634143 PMID:21136691 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403 		JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions
decreases expression		 ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of LDLR mRNA; Acrylamide inhibits the reaction [Streptozocin results in decreased expression of LDLR mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of LDLR mRNA] CTD PMID:33359794 PMID:34896238 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lep leptin multiple interactions EXP
ISO		 [Streptozocin co-treated with Dietary Fats] results in increased expression of LEP protein; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of LEP protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of LEP protein]
[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of LEP protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of LEP protein; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of LEP protein]; Omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of LEP protein]		 CTD PMID:24854284 PMID:29988851 PMID:32410268 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lepr leptin receptor multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of LEPR mRNA CTD PMID:29127188 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
G Lgals3 galectin 3 multiple interactions
increases expression		 EXP [resveratrol co-treated with Streptozocin] results in increased expression of LGALS3 mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of LGALS3 mRNA] CTD PMID:16684804 PMID:25905778 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
G Lhb luteinizing hormone subunit beta decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in decreased expression of LHB protein
[Streptozocin co-treated with Fructose] results in decreased expression of LHB protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in decreased expression of LHB protein]
Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of LHB protein]; vitexin inhibits the reaction [Streptozocin results in decreased expression of LHB protein]		 CTD PMID:19931367 PMID:30365938 PMID:34656705 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Limk2 LIM domain kinase 2 increases phosphorylation
multiple interactions		 EXP Streptozocin results in increased phosphorylation of LIMK2 protein
fasudil inhibits the reaction [Streptozocin results in increased phosphorylation of LIMK2 protein]		 CTD PMID:22062134 NCBI chr14:78,208,182...78,286,106
Ensembl chr14:78,218,063...78,286,007 		JBrowse link
G Lipc lipase C, hepatic type multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of LIPC protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of LIPC protein] CTD PMID:33484791 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464 		JBrowse link
G Lipe lipase E, hormone sensitive type multiple interactions
increases expression		 EXP vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of LIPE mRNA] CTD PMID:16684804 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310 		JBrowse link
G Litaf lipopolysaccharide-induced TNF factor decreases expression EXP Streptozocin results in decreased expression of LITAF mRNA CTD PMID:25905778 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763 		JBrowse link
G LOC102549061 histone H2B type 1-N-like multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of H2BC3 mRNA CTD PMID:33484791 NCBI chr17:41,380,056...41,380,686 JBrowse link
G Lpin2 lipin 2 increases expression EXP Streptozocin results in increased expression of LPIN2 mRNA CTD PMID:25905778 NCBI chr 9:111,083,378...111,158,193
Ensembl chr 9:111,083,745...111,158,193 		JBrowse link
G Lpl lipoprotein lipase multiple interactions EXP
ISO		 [Streptozocin co-treated with Cadmium] results in decreased activity of LPL protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein; [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of LPL protein]; tetrahydrocurcumin results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein]
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of LPL mRNA]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of LPL mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of LPL mRNA		 CTD PMID:20696151 PMID:25240712 PMID:25446853 PMID:29127188 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Lrp5 LDL receptor related protein 5 affects expression ISO Streptozocin affects the expression of LRP5 mRNA CTD PMID:18583417 NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581 		JBrowse link
G Lst1 leukocyte specific transcript 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of LST1 mRNA CTD PMID:25905778 NCBI chr20:3,634,680...3,639,731
Ensembl chr20:3,634,749...3,637,997 		JBrowse link
G Lyz2 lysozyme 2 multiple interactions
increases expression		 EXP vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of LYZ mRNA] CTD PMID:16684804 NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106 		JBrowse link
G Mafa MAF bZIP transcription factor A multiple interactions
decreases expression		 ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of MAFA mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of MAFA mRNA]; octylphenol inhibits the reaction [Streptozocin results in decreased expression of MAFA mRNA] CTD PMID:24781736 PMID:29935216 PMID:33359794 NCBI chr 7:107,432,292...107,435,084
Ensembl chr 7:107,433,605...107,434,690 		JBrowse link
G Mak male germ cell-associated kinase multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of MAK mRNA CTD PMID:33484791 NCBI chr17:23,683,753...23,731,125
Ensembl chr17:23,693,878...23,730,001 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha multiple interactions EXP [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in increased expression of MAP1LC3A protein CTD PMID:35786680 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions EXP [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of MAP1LC3B mRNA CTD PMID:35786680 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions
decreases expression		 ISO
EXP		 Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of MAP2 protein]; Physostigmine inhibits the reaction [Streptozocin results in decreased expression of MAP2 protein]
Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of MAP2 protein]		 CTD PMID:28499986 PMID:38049026 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAP2K4 protein; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAP2K4 protein] CTD PMID:26522834 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 increases expression EXP Streptozocin results in increased expression of MAP2K6 mRNA CTD PMID:25905778 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions
increases expression		 ISO
EXP		 [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAP3K5 protein; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAP3K5 protein]; Streptozocin promotes the reaction [MAP3K5 protein results in increased expression of SERPINE1 protein]
Streptozocin results in increased expression of MAP3K5 protein
resveratrol inhibits the reaction [Streptozocin results in increased expression of MAP3K5 protein]		 CTD PMID:16731828 PMID:26499206 PMID:26522834 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
decreases phosphorylation
increases expression
increases activity		 EXP
ISO		 1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein]]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Botulinum Toxins, Type A inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; capsazepine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Donepezil inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein]; Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein]; Metformin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of MAPK1 mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of MAPK1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; RN 1734 inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Streptozocin results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein]
3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of and results in decreased phosphorylation of MAPK1 protein; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of MAPK1 protein; [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK1 protein; arachidonyl-2-chloroethylamide promotes the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK1 protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of and results in decreased phosphorylation of MAPK1 protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of MAPK1 protein]; Streptozocin promotes the reaction [NTN1 protein results in increased phosphorylation of MAPK1 protein]
Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK1 protein]
Streptozocin results in increased expression of MAPK1 mRNA; Streptozocin results in increased expression of MAPK1 protein
Streptozocin results in increased activity of MAPK1 protein		 CTD PMID:12642375 PMID:17063547 PMID:19002579 PMID:19133311 PMID:19682444 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk10 mitogen activated protein kinase 10 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of MAPK10 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MAPK10 mRNA] CTD PMID:33484791 NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201 		JBrowse link
G Mapk11 mitogen-activated protein kinase 11 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of MAPK11 protein CTD PMID:34310909 NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation
multiple interactions		 ISO
EXP		 Streptozocin results in increased phosphorylation of MAPK14 protein
Atorvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK14 protein]		 CTD PMID:15232685 PMID:17589825 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases activity
increases phosphorylation
decreases phosphorylation
multiple interactions
increases expression		 EXP
ISO		 Streptozocin results in increased activity of MAPK3 protein
Streptozocin results in increased phosphorylation of MAPK3 protein
Streptozocin results in decreased phosphorylation of MAPK3 protein
3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of MAPK3 protein; [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK3 protein; arachidonyl-2-chloroethylamide promotes the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK3 protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of MAPK3 protein]; Streptozocin promotes the reaction [NTN1 protein results in increased phosphorylation of MAPK3 protein]
Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK3 protein]
1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein]]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Botulinum Toxins, Type A inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; capsazepine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Donepezil inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein]; Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein]; Metformin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; RN 1734 inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Streptozocin results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein]
Streptozocin results in increased expression of MAPK3 mRNA		 CTD PMID:12642375 PMID:19002579 PMID:19133311 PMID:19682444 PMID:20053369 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation		 ISO
EXP		 Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK8 protein]
Streptozocin results in increased phosphorylation of MAPK8 protein
[Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]; Ramipril inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]
[Carnosine co-treated with asiatic acid] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]; [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein; asiatic acid inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]; Carnosine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein]		 CTD PMID:25541468 PMID:26522834 PMID:30802477 PMID:31062909 PMID:33484791 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases expression		 EXP
ISO		 chromium mesoporphyrin inhibits the reaction [Hemin inhibits the reaction [Streptozocin results in increased expression of MAPK9 mRNA]]; Hemin inhibits the reaction [Streptozocin results in increased expression of MAPK9 mRNA]
[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK9 protein; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK9 protein]
Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK9 protein]		 CTD PMID:19190261 PMID:25541468 PMID:26522834 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 multiple interactions
increases expression		 ISO telmisartan inhibits the reaction [Streptozocin results in increased expression of MAPKAPK2 protein modified form] CTD PMID:21381899 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457 		JBrowse link
G Mapt microtubule-associated protein tau increases phosphorylation
increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased phosphorylation of MAPT protein
Streptozocin results in increased expression of MAPT protein modified form
Melatonin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein]; Melatonin metabolite inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein]; N-acetyl-N-formyl-5-methoxykynurenamine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein]
5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of MAPT protein modified form]; Folic Acid inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein]; SOD2 protein inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of MAPT protein modified form]		 CTD PMID:20976160 PMID:28422052 PMID:31833155 PMID:34428446 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor decreases expression
multiple interactions		 ISO Streptozocin results in decreased expression of MAS1 protein
CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of MAS1 protein]; Telmisartan inhibits the reaction [Streptozocin results in decreased expression of MAS1 protein]		 CTD PMID:21381899 PMID:29266779 NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709 		JBrowse link
G Mat1a methionine adenosyltransferase 1A multiple interactions ISO [Streptozocin co-treated with Dietary Fats] affects the expression of MAT1A mRNA CTD PMID:29127188 NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274 		JBrowse link
G Mat2a methionine adenosyltransferase 2A multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of MAT2A mRNA CTD PMID:29127188 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493 		JBrowse link
G Mbp myelin basic protein multiple interactions
decreases expression		 EXP 20-alpha-Dihydroprogesterone inhibits the reaction [Streptozocin results in decreased expression of MBP mRNA]; Progesterone inhibits the reaction [Streptozocin results in decreased expression of MBP mRNA]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of MBP protein]
Streptozocin results in decreased expression of MBP mRNA; Streptozocin results in decreased expression of MBP protein		 CTD PMID:20349157 PMID:38049026 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Mcemp1 mast cell-expressed membrane protein 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of MCEMP1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MCEMP1 mRNA] CTD PMID:33484791 NCBI chr12:1,721,781...1,727,350
Ensembl chr12:1,718,730...1,725,986 		JBrowse link
G Mdh1 malate dehydrogenase 1 multiple interactions
increases expression		 EXP Trientine inhibits the reaction [Streptozocin results in increased expression of MDH1 protein] CTD PMID:21136691 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925 		JBrowse link
G Mdh2 malate dehydrogenase 2 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of MDH2 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of MDH2 protein]		 CTD PMID:19634143 NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271 		JBrowse link
G Mecr mitochondrial trans-2-enoyl-CoA reductase increases expression EXP Streptozocin results in increased expression of MECR mRNA CTD PMID:25905778 NCBI chr 5:144,029,684...144,056,373
Ensembl chr 5:144,029,731...144,055,863 		JBrowse link
G Mef2c myocyte enhancer factor 2C decreases expression
multiple interactions		 ISO Streptozocin results in decreased expression of MEF2C mRNA
SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MEF2C mRNA]		 CTD PMID:27629361 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mefv MEFV innate immunity regulator, pyrin multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of MEFV mRNA CTD PMID:33484791 NCBI chr10:11,786,948...11,796,977
Ensembl chr10:11,787,422...11,796,973 		JBrowse link
G Mep1a meprin A subunit alpha multiple interactions EXP Streptozocin results in decreased activity of and results in decreased expression of MEP1A protein CTD PMID:15942051 NCBI chr 9:17,474,634...17,504,147
Ensembl chr 9:17,474,619...17,504,147 		JBrowse link
G Mff mitochondrial fission factor multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of MFF mRNA CTD PMID:33812996 NCBI chr 9:84,007,798...84,036,039
Ensembl chr 9:84,007,798...84,036,039 		JBrowse link
G Mfn2 mitofusin 2 multiple interactions
decreases expression		 EXP
ISO		 ferulic acid inhibits the reaction [Streptozocin results in decreased expression of MFN2 protein]; MFN2 protein mutant form inhibits the reaction [Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter]]; MFN2 protein mutant form inhibits the reaction [Streptozocin results in increased expression of COL4A1 mRNA]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of MFN2 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of MFN2 mRNA]		 CTD PMID:27997345 PMID:31029786 PMID:33812996 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mgll monoglyceride lipase multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of MGLL mRNA CTD PMID:25905778 NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases response to substance ISO MGMT protein results in decreased susceptibility to Streptozocin CTD PMID:16039682 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of MGST2 mRNA CTD PMID:29127188 NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828 		JBrowse link
G Micu1 mitochondrial calcium uptake 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 protein; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 protein]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 protein] CTD PMID:37337224 NCBI chr20:27,668,681...27,816,322
Ensembl chr20:27,668,747...27,814,964 		JBrowse link
G Mir100 microRNA 100 decreases expression ISO Streptozocin results in decreased expression of MIR100 mRNA CTD PMID:27629361 NCBI chr 8:41,901,225...41,901,304
Ensembl chr 8:41,901,225...41,901,304 		JBrowse link
G Mir101-2 microRNA 101-2 increases expression ISO Streptozocin results in increased expression of MIR101B mRNA CTD PMID:27629361 NCBI chr 1:226,860,371...226,860,467
Ensembl chr 1:226,860,371...226,860,467 		JBrowse link
G Mir106a microRNA 106a increases expression ISO Streptozocin results in increased expression of MIR106A mRNA CTD PMID:27629361 NCBI chr  X:132,422,584...132,422,661
Ensembl chr  X:132,422,584...132,422,661 		JBrowse link
G Mir10a microRNA 10a multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of MIR10A mRNA; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MIR10A mRNA]; MIR10A mRNA affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein] CTD PMID:27292126 NCBI chr10:81,283,171...81,283,280
Ensembl chr10:81,283,171...81,283,280 		JBrowse link
G Mir125b1 microRNA 125b-1 increases expression ISO Streptozocin results in increased expression of MIR125B-1 mRNA CTD PMID:27629361 NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052 		JBrowse link
G Mir128-1 microRNA 128-1 increases expression ISO Streptozocin results in increased expression of MIR128-1 mRNA CTD PMID:27629361 NCBI chr13:39,699,449...39,699,530
Ensembl chr13:39,699,449...39,699,530 		JBrowse link
G Mir1306 microRNA 1306 increases expression ISO Streptozocin results in increased expression of MIR1306 mRNA CTD PMID:27629361 NCBI chr11:82,709,651...82,709,723
Ensembl chr11:82,709,637...82,709,719 		JBrowse link
G Mir132 microRNA 132 increases expression ISO Streptozocin results in increased expression of MIR132 mRNA CTD PMID:27629361 NCBI chr10:60,023,696...60,023,796
Ensembl chr10:60,023,696...60,023,796 		JBrowse link
G Mir135a microRNA 135a increases expression ISO Streptozocin results in increased expression of MIR135A-2 mRNA CTD PMID:27629361 NCBI chr 7:26,611,990...26,612,089
Ensembl chr 7:26,611,990...26,612,089 		JBrowse link
G Mir135b microRNA 135b increases expression ISO Streptozocin results in increased expression of MIR135B mRNA CTD PMID:27629361 NCBI chr13:43,638,857...43,638,953
Ensembl chr13:43,638,857...43,638,953 		JBrowse link
G Mir140 microRNA 140 multiple interactions
increases expression		 EXP
ISO		 [Antagomirs results in decreased expression of MIR140 mRNA] inhibits the reaction [Streptozocin results in decreased expression of SNX12 protein]
streptozocin increases expression of Mir140 RNA in heart		 CTD
RGD		 PMID:32062618 PMID:36044268 RGD:156430337 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir142 microRNA 142 multiple interactions
increases expression		 ISO SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR142 mRNA] CTD PMID:27629361 NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967 		JBrowse link
G Mir144 microRNA 144 increases expression
multiple interactions		 ISO Streptozocin results in increased expression of MIR144 mRNA
SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR144 mRNA]		 CTD PMID:27629361 NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430 		JBrowse link
G Mir146a microRNA 146a increases expression
multiple interactions		 EXP Streptozocin results in increased expression of MIR146A mRNA
Glyburide inhibits the reaction [Streptozocin results in increased expression of MIR146A mRNA]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of MIR146A mRNA]		 CTD PMID:36504472 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Mir146b microRNA 146b increases expression ISO Streptozocin results in increased expression of MIR146B mRNA CTD PMID:27629361 NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525 		JBrowse link
G Mir152 microRNA 152 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of MIR152 mRNA]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of MIR152 mRNA]] CTD PMID:36547818 NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020 		JBrowse link
G Mir155 microRNA 155 decreases expression ISO Streptozocin results in decreased expression of MIR155 mRNA CTD PMID:27629361 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718 		JBrowse link
G Mir184 microRNA 184 decreases expression ISO Streptozocin results in decreased expression of MIR184 mRNA CTD PMID:27629361 NCBI chr 8:90,343,134...90,343,210
Ensembl chr 8:90,343,134...90,343,210 		JBrowse link
G Mir188 microRNA 188 increases expression ISO Streptozocin results in increased expression of MIR188 mRNA CTD PMID:27629361 NCBI chr  X:15,247,715...15,247,794
Ensembl chr  X:15,247,715...15,247,794 		JBrowse link
G Mir18a microRNA 18a decreases expression ISO Streptozocin results in decreased expression of MIR18 mRNA CTD PMID:27629361 NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860 		JBrowse link
G Mir191 microRNA 191 increases expression ISO Streptozocin results in increased expression of MIR191 mRNA CTD PMID:27629361 NCBI chr 8:109,264,098...109,264,188 JBrowse link
G Mir194-1 microRNA 194-1 increases expression ISO Streptozocin results in increased expression of MIR194-1 mRNA CTD PMID:27629361 NCBI chr13:96,851,166...96,851,248
Ensembl chr13:96,851,166...96,851,248 		JBrowse link
G Mir196c microRNA 196c decreases expression ISO Streptozocin results in decreased expression of MIR196A-1 mRNA CTD PMID:27629361 NCBI chr10:81,231,006...81,231,085
Ensembl chr10:81,231,006...81,231,085 		JBrowse link
G Mir200a microRNA 200a increases expression
multiple interactions		 ISO Streptozocin results in increased expression of MIR200A mRNA
2,5-dihydroxybenzoic acid promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of MIR200A]; [Streptozocin co-treated with Niacinamide] results in increased expression of MIR200A; Metformin promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of MIR200A]		 CTD PMID:27629361 PMID:37120126 NCBI chr 5:166,648,494...166,648,582 JBrowse link
G Mir205 microRNA 205 increases expression ISO Streptozocin results in increased expression of MIR205 mRNA CTD PMID:27629361 NCBI chr13:105,035,878...105,035,985
Ensembl chr13:105,035,878...105,035,985 		JBrowse link
G Mir20b microRNA 20b decreases expression ISO Streptozocin results in decreased expression of MIR20B mRNA CTD PMID:27629361 NCBI chr  X:132,422,211...132,422,282
Ensembl chr  X:132,422,211...132,422,282 		JBrowse link
G Mir216a microRNA 216a increases expression ISO Streptozocin results in increased expression of MIR216A mRNA CTD PMID:27629361 NCBI chr14:102,524,105...102,524,210
Ensembl chr14:102,524,105...102,524,210 		JBrowse link
G Mir217 microRNA 217 increases expression
decreases expression		 ISO
EXP		 Streptozocin results in increased expression of MIR217 mRNA
Streptozocin results in decreased expression of MIR217 mRNA		 CTD PMID:27629361 PMID:33283391 NCBI chr14:102,531,505...102,531,609
Ensembl chr14:102,531,505...102,531,609 		JBrowse link
G Mir218-2 microRNA 218-2 increases expression ISO Streptozocin results in increased expression of MIR218-2 mRNA CTD PMID:27629361 NCBI chr10:20,068,451...20,068,560
Ensembl chr10:20,068,451...20,068,560 		JBrowse link
G Mir219a1 microRNA 219a-1 increases expression ISO Streptozocin results in increased expression of MIR219A-1 mRNA CTD PMID:27629361 NCBI chr20:4,829,687...4,829,796
Ensembl chr20:4,829,687...4,829,796 		JBrowse link
G Mir222 microRNA 222 increases expression ISO Streptozocin results in increased expression of MIR222 mRNA CTD PMID:27629361 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006 		JBrowse link
G Mir27a microRNA 27a multiple interactions
decreases expression		 ISO SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MIR27A mRNA] CTD PMID:27629361 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917 		JBrowse link
G Mir293 microRNA 293 increases expression ISO Streptozocin results in increased expression of MIR293 mRNA CTD PMID:27629361 NCBI chr 1:65,963,050...65,963,121
Ensembl chr 1:65,963,050...65,963,121 		JBrowse link
G Mir298 microRNA 298 increases expression ISO Streptozocin results in increased expression of MIR298 mRNA CTD PMID:27629361 NCBI chr 3:163,052,291...163,052,372
Ensembl chr 3:163,052,291...163,052,372 		JBrowse link
G Mir29a microRNA 29a multiple interactions
decreases expression		 ISO MIR29A mRNA inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of CNR1 mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of CNR1 protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of COL4A2 mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of JUN mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]
Streptozocin results in decreased expression of MIR29A mRNA		 CTD PMID:30642005 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir322 microRNA 322 multiple interactions
decreases expression		 ISO SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MIR322 mRNA] CTD PMID:27629361 NCBI chr  X:132,806,594...132,806,688
Ensembl chr  X:132,806,594...132,806,688 		JBrowse link
G Mir323 microRNA 323 increases expression ISO Streptozocin results in increased expression of MIR323 mRNA CTD PMID:27629361 NCBI chr 6:128,725,539...128,725,624
Ensembl chr 6:128,725,539...128,725,624 		JBrowse link
G Mir33 microRNA 33 multiple interactions EXP [Fructose co-treated with Streptozocin] results in increased expression of MIR33A mRNA; Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in increased expression of MIR33A mRNA] CTD PMID:31468622 NCBI chr 7:113,713,855...113,713,923
Ensembl chr 7:113,713,855...113,713,923 		JBrowse link
G Mir330 microRNA 330 increases expression ISO Streptozocin results in increased expression of MIR330 mRNA CTD PMID:27629361 NCBI chr 1:78,833,178...78,833,274
Ensembl chr 1:78,833,178...78,833,274 		JBrowse link
G Mir3545 microRNA 3545 affects expression ISO Streptozocin affects the expression of MIR203 mRNA CTD PMID:27629361 NCBI chr 6:131,199,542...131,199,656
Ensembl chr 6:131,199,542...131,199,656 		JBrowse link
G Mir375 microRNA 375 increases expression EXP Streptozocin results in increased expression of MIR375 mRNA CTD PMID:27521901 NCBI chr 9:76,457,911...76,457,985
Ensembl chr 9:76,457,911...76,457,985 		JBrowse link
G Mir377 microRNA 377 multiple interactions ISO [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR377]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR377 CTD PMID:38282657 NCBI chr 6:128,755,051...128,755,122 JBrowse link
G Mir412 microRNA 412 increases expression ISO Streptozocin results in increased expression of MIR412 mRNA CTD PMID:27629361 NCBI chr 6:128,757,932...128,758,001
Ensembl chr 6:128,757,926...128,758,005 		JBrowse link
G Mir433 microRNA 433 decreases expression ISO Streptozocin results in decreased expression of MIR433 mRNA CTD PMID:27629361 NCBI chr 6:128,545,119...128,545,211
Ensembl chr 6:128,545,112...128,545,217 		JBrowse link
G Mir448 microRNA 448 multiple interactions
increases expression		 ISO SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR448 mRNA] CTD PMID:27629361 NCBI chr  X:110,829,918...110,830,029
Ensembl chr  X:110,829,918...110,830,029 		JBrowse link
G Mir451a microRNA 451a increases expression ISO Streptozocin results in increased expression of MIR451A mRNA CTD PMID:27629361 NCBI chr10:62,961,520...62,961,591
Ensembl chr10:62,961,520...62,961,591 		JBrowse link
G Mir490 microRNA 490 decreases expression ISO Streptozocin results in decreased expression of MIR490 mRNA CTD PMID:27629361 NCBI chr 4:65,047,548...65,047,631
Ensembl chr 4:65,047,548...65,047,631 		JBrowse link
G Mir494 microRNA 494 multiple interactions ISO [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR494]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR494 CTD PMID:38282657 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793 		JBrowse link
G Mir497 microRNA 497 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of MIR497
MIR497 inhibits the reaction [Streptozocin results in decreased expression of MIR497 protein]; MIR497 inhibits the reaction [Streptozocin results in increased expression of USP15 mRNA]; MIR497 inhibits the reaction [Streptozocin results in increased expression of USP15 protein]		 CTD PMID:35478295 NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584 		JBrowse link
G Mir499a microRNA 499a decreases expression ISO Streptozocin results in decreased expression of MIR499 mRNA CTD PMID:27629361 NCBI chr 3:144,110,469...144,110,533
Ensembl chr 3:144,110,469...144,110,533 		JBrowse link
G Mir504 microRNA 504 increases expression ISO Streptozocin results in increased expression of MIR504 mRNA CTD PMID:27629361 NCBI chr  X:137,318,540...137,318,616
Ensembl chr  X:137,318,540...137,318,616 		JBrowse link
G Mir544 microRNA 544 increases expression ISO Streptozocin results in increased expression of MIR544 mRNA CTD PMID:27629361 NCBI chr 6:128,743,530...128,743,607
Ensembl chr 6:128,743,530...128,743,607 		JBrowse link
G Mir582 microRNA 582 increases expression ISO Streptozocin results in increased expression of MIR582 mRNA CTD PMID:27629361 NCBI chr 2:40,928,571...40,928,651
Ensembl chr 2:40,928,571...40,928,651 		JBrowse link
G Mir671 microRNA 671 increases expression ISO Streptozocin results in increased expression of MIR671 mRNA CTD PMID:27629361 NCBI chr 4:10,580,747...10,580,827
Ensembl chr 4:10,580,738...10,580,835 		JBrowse link
G Mir873 microRNA 873 increases expression ISO Streptozocin results in increased expression of MIR873A mRNA CTD PMID:27629361 NCBI chr 5:51,356,919...51,356,995
Ensembl chr 5:51,356,919...51,356,995 		JBrowse link
G Mir875 microRNA 875 increases expression ISO Streptozocin results in increased expression of MIR875 mRNA CTD PMID:27629361 NCBI chr 7:66,861,955...66,862,027
Ensembl chr 7:66,861,955...66,862,027 		JBrowse link
G Mir93 microRNA 93 increases expression ISO Streptozocin results in increased expression of MIR93 mRNA CTD PMID:27629361 NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221 		JBrowse link
G Mir96 microRNA 96 increases expression ISO Streptozocin results in increased expression of MIR96 mRNA CTD PMID:27629361 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516 		JBrowse link
G Mir98 microRNA 98 decreases expression ISO Streptozocin results in decreased expression of MIR98 mRNA CTD PMID:27629361 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342 		JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 increases expression EXP Streptozocin results in increased expression of MKNK2 mRNA CTD PMID:25905778 NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827 		JBrowse link
G Mme membrane metallo-endopeptidase decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of MME protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of MME protein]		 CTD PMID:19634143 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792 		JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression EXP Streptozocin results in increased expression of MMP1 protein CTD PMID:35993117 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of MMP13 mRNA
esculetin inhibits the reaction [Streptozocin results in increased expression of MMP13 mRNA]		 CTD PMID:21450970 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases secretion
decreases expression
increases expression
increases activity		 ISO
EXP		 PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA]
Streptozocin results in decreased secretion of MMP2 protein
Streptozocin results in decreased expression of MMP2 mRNA; Streptozocin results in decreased expression of MMP2 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of MMP2 protein]; ESR2 protein affects the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased expression of MMP2 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of MMP2 protein]
Streptozocin results in increased expression of MMP2 mRNA; Streptozocin results in increased expression of MMP2 protein
Streptozocin results in increased activity of MMP2 protein
benazepril inhibits the reaction [Streptozocin results in decreased expression of MMP2 mRNA]; benazepril inhibits the reaction [Streptozocin results in decreased expression of MMP2 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of MMP2 protein]; Olive Oil inhibits the reaction [Streptozocin results in increased activity of MMP2 protein]; rhapontin inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA]; Tropisetron inhibits the reaction [Streptozocin results in decreased expression of MMP2 mRNA]		 CTD PMID:16732983 PMID:20446767 PMID:20821936 PMID:23471663 PMID:25246140 More... NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression
decreases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of MMP3 mRNA
Streptozocin results in decreased expression of MMP3 mRNA
PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP3 mRNA]		 CTD PMID:18246672 PMID:20446767 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mmp7 matrix metallopeptidase 7 multiple interactions
increases expression		 ISO PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP7 mRNA]
[Streptozocin co-treated with Dietary Fats] results in increased expression of MMP7 mRNA		 CTD PMID:20446767 PMID:29127188 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
increases activity
increases expression		 ISO
EXP		 PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]
Streptozocin results in decreased expression of MMP9 mRNA
[Dietary Fats co-treated with Streptozocin] results in increased expression of MMP9 mRNA; formononetin inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of MMP9 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of MMP9 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to MMP9 promoter]]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin promotes the reaction [RELA protein binds to MMP9 promoter]]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [PARP1 protein binds to MMP9 promoter]]; Streptozocin promotes the reaction [JUN protein binds to MMP9 promoter]; Streptozocin promotes the reaction [PARP1 protein binds to MMP9 promoter]; Streptozocin promotes the reaction [RELA protein binds to MMP9 promoter]
Streptozocin results in increased activity of MMP9 protein
[Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of MMP9 protein; idebenone inhibits the reaction [Streptozocin results in increased expression of MMP9 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of MMP9 protein]; Olive Oil inhibits the reaction [Streptozocin results in increased activity of MMP9 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; Rosiglitazone inhibits the reaction [Streptozocin deficiency results in increased expression of MMP9 mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; Tropisetron inhibits the reaction [Streptozocin results in decreased expression of MMP9 mRNA]
Streptozocin results in increased expression of MMP9 mRNA; Streptozocin results in increased expression of MMP9 protein		 CTD PMID:19236438 PMID:19820293 PMID:20446767 PMID:22191573 PMID:25246140 More... NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mmrn1 multimerin 1 increases expression EXP Streptozocin results in increased expression of MMRN1 protein CTD PMID:21450970 NCBI chr 4:89,875,408...89,950,814
Ensembl chr 4:89,903,174...89,950,474 		JBrowse link
G Mogat1 monoacylglycerol O-acyltransferase 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of MOGAT1 mRNA CTD PMID:29127188 NCBI chr 9:79,980,963...79,988,513
Ensembl chr 9:79,956,649...79,988,513 		JBrowse link
G Mpg N-methylpurine-DNA glycosylase affects response to substance ISO MPG protein affects the susceptibility to Streptozocin CTD PMID:17098815 NCBI chr10:15,396,246...15,402,528
Ensembl chr10:15,395,782...15,402,520 		JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity		 ISO
EXP		 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Lisinopril inhibits the reaction [Streptozocin results in increased activity of MPO protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Telmisartan inhibits the reaction [Streptozocin results in increased activity of MPO protein]]; [Streptozocin co-treated with Dextran Sulfate] results in increased activity of MPO protein; Donepezil inhibits the reaction [Streptozocin results in increased activity of MPO protein]; Lisinopril inhibits the reaction [Streptozocin results in increased activity of MPO protein]; Telmisartan inhibits the reaction [Streptozocin results in increased activity of MPO protein]
Streptozocin results in increased expression of and results in increased activity of MPO protein		 CTD PMID:23060470 PMID:24924950 PMID:34039237 PMID:34964214 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mpped1 metallophosphoesterase domain containing 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of MPPED1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MPPED1 mRNA] CTD PMID:33484791 NCBI chr 7:114,932,221...115,011,797
Ensembl chr 7:114,944,764...115,011,787 		JBrowse link
G Mpz myelin protein zero multiple interactions
decreases expression		 EXP 20-alpha-Dihydroprogesterone inhibits the reaction [Streptozocin results in decreased expression of MPZ mRNA]; Progesterone inhibits the reaction [Streptozocin results in decreased expression of MPZ mRNA] CTD PMID:17187935 NCBI chr13:83,570,811...83,576,680
Ensembl chr13:83,570,811...83,576,679 		JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions
decreases expression		 ISO AM6545 inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]] CTD PMID:30184259 NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857 		JBrowse link
G Mroh6 maestro heat-like repeat family member 6 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of MROH6 mRNA CTD PMID:33484791 NCBI chr 7:107,566,212...107,576,469
Ensembl chr 7:107,569,554...107,574,173 		JBrowse link
G Mrpl14 mitochondrial ribosomal protein L14 affects expression ISO Streptozocin affects the expression of MRPL14 mRNA CTD PMID:18583417 NCBI chr 9:15,302,840...15,315,195
Ensembl chr 9:15,302,427...15,315,267 		JBrowse link
G Mrpl18 mitochondrial ribosomal protein L18 affects expression ISO Streptozocin affects the expression of MRPL18 mRNA CTD PMID:18583417 NCBI chr 1:47,837,169...47,841,987
Ensembl chr 1:47,836,561...47,841,987 		JBrowse link
G Mrpl42 mitochondrial ribosomal protein L42 affects expression ISO Streptozocin affects the expression of MRPL42 mRNA CTD PMID:18583417 NCBI chr 7:30,117,977...30,141,757
Ensembl chr 7:30,117,977...30,141,639 		JBrowse link
G Mrps7 mitochondrial ribosomal protein S7 affects expression ISO Streptozocin affects the expression of MRPS7 mRNA CTD PMID:18583417 NCBI chr10:100,843,691...100,846,838
Ensembl chr10:100,843,356...100,847,129 		JBrowse link
G Ms4a3 membrane spanning 4-domains A3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of MS4A3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MS4A3 mRNA] CTD PMID:33484791 NCBI chr 1:208,462,300...208,480,129
Ensembl chr 1:208,462,301...208,480,101 		JBrowse link
G Ms4a6a membrane spanning 4-domains A6A multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of MS4A6A mRNA CTD PMID:25905778 NCBI chr 1:208,401,465...208,414,831
Ensembl chr 1:208,401,466...208,414,758 		JBrowse link
G Ms4a6bl1 membrane-spanning 4-domains, subfamily A, member 6B-like 1 multiple interactions EXP [Resveratrol co-treated with Streptozocin] results in increased expression of MS4A6BL1 mRNA CTD PMID:25905778 NCBI chr 1:208,243,561...208,255,400
Ensembl chr 1:208,243,559...208,257,340 		JBrowse link
G Msln mesothelin multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of MSLN mRNA CTD PMID:29127188 NCBI chr10:14,771,946...14,781,382
Ensembl chr10:14,771,961...14,777,643 		JBrowse link
G Mt1 metallothionein 1 increases expression
decreases expression
multiple interactions		 EXP Streptozocin results in increased expression of MT1A mRNA
Streptozocin results in decreased expression of MT1A mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of MT1A mRNA]; Zinc promotes the reaction [Streptozocin results in increased expression of MT1A mRNA]		 CTD PMID:16684804 PMID:19369054 PMID:24927960 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049 		JBrowse link
G Mt2A metallothionein 2A decreases expression EXP Streptozocin results in decreased expression of MT2A mRNA CTD PMID:24927960 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mt3 metallothionein 3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of MT3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MT3 mRNA] CTD PMID:33484791 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of MTHFR mRNA CTD PMID:29127188 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Mtmr7 myotubularin related protein 7 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of MTMR7 mRNA CTD PMID:25905778 NCBI chr16:51,641,267...51,732,212
Ensembl chr16:51,641,190...51,732,182 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
increases phosphorylation
increases expression
decreases expression		 EXP
ISO		 resveratrol inhibits the reaction [Streptozocin results in decreased expression of MTOR mRNA]
streptozocin increases increases phosphorylation of Mtor protein in heart
Streptozocin results in increased expression of MTOR protein modified form
5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of MTOR protein modified form]; [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of MTOR protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of MTOR protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of MTOR protein modified form]		 CTD
RGD		 PMID:26071184 PMID:33484791 PMID:34428446 PMID:36044268 RGD:156430337 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase decreases activity
multiple interactions		 EXP
ISO		 Streptozocin results in decreased activity of MTR protein
[Streptozocin co-treated with Dietary Fats] results in decreased expression of MTR mRNA		 CTD PMID:16835399 PMID:29127188 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions
increases expression		 ISO
EXP		 [Dietary Fats co-treated with Streptozocin] results in increased expression of MYD88 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of MYD88 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of MYD88 protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MYD88 mRNA]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MYD88 protein]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of MYD88 mRNA]
Streptozocin results in increased expression of MYD88 mRNA
myrtenol inhibits the reaction [Streptozocin results in increased expression of MYD88 mRNA]		 CTD PMID:27769711 PMID:34477272 PMID:37482253 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Myh3 myosin heavy chain 3 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of MYH3 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of MYH3 mRNA]		 CTD PMID:16684804 NCBI chr10:51,770,177...51,793,994
Ensembl chr10:51,770,177...51,793,992 		JBrowse link
G Myh6 myosin heavy chain 6 multiple interactions
decreases expression		 EXP Enalapril inhibits the reaction [Streptozocin results in decreased expression of MYH6 mRNA]; Enalapril inhibits the reaction [Streptozocin results in decreased expression of MYH6 protein]; Losartan inhibits the reaction [Streptozocin results in decreased expression of MYH6 mRNA]; Losartan inhibits the reaction [Streptozocin results in decreased expression of MYH6 protein]
Streptozocin results in decreased expression of MYH6 mRNA; Streptozocin results in decreased expression of MYH6 protein		 CTD PMID:15362513 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720 		JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions
increases expression		 EXP Enalapril inhibits the reaction [Streptozocin results in increased expression of MYH7 mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of MYH7 protein]; Losartan inhibits the reaction [Streptozocin results in increased expression of MYH7 mRNA]; Losartan inhibits the reaction [Streptozocin results in increased expression of MYH7 protein]
Streptozocin results in increased expression of MYH7 mRNA; Streptozocin results in increased expression of MYH7 protein		 CTD PMID:15362513 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase increases activity
multiple interactions		 EXP Streptozocin results in increased activity of NAGLU protein
Metformin inhibits the reaction [Streptozocin results in increased activity of NAGLU protein]		 CTD PMID:33639173 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression
multiple interactions		 EXP Streptozocin results in increased expression of NAMPT mRNA
[Streptozocin co-treated with Dietary Fats] results in increased expression of NAMPT protein; Rosiglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NAMPT protein]		 CTD PMID:25905778 PMID:29441829 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100 		JBrowse link
G Nat8 N-acetyltransferase 8 multiple interactions
increases expression		 EXP [resveratrol co-treated with Streptozocin] results in decreased expression of NAT8 mRNA
Streptozocin results in increased expression of NAT8 mRNA		 CTD PMID:25905778 NCBI chr 4:118,279,521...118,284,671
Ensembl chr 4:118,270,954...118,281,763 		JBrowse link
G Nat8f3 N-acetyltransferase 8 (GCN5-related) family member 3 increases expression EXP Streptozocin results in increased expression of NAT8F3 mRNA CTD PMID:25905778 NCBI chr 4:118,241,792...118,246,010
Ensembl chr 4:118,239,304...118,285,500 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of NCF1 protein
Streptozocin results in increased expression of NCF1 mRNA; Streptozocin results in increased expression of NCF1 protein
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of NCF1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of NCF1 protein]; [Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of NCF1 protein; Cholesterol, Dietary promotes the reaction [Streptozocin results in increased expression of NCF1 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of NCF1 protein]
telmisartan inhibits the reaction [Streptozocin results in increased expression of NCF1 protein]; terutroban inhibits the reaction [Streptozocin results in increased expression of NCF1 protein]		 CTD PMID:14871415 PMID:16380483 PMID:20399799 PMID:21381899 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
G Ncf2 neutrophil cytosolic factor 2 increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of NCF2 protein
[Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of NCF2 mRNA
telmisartan inhibits the reaction [Streptozocin results in increased expression of NCF2 protein]		 CTD PMID:21381899 PMID:35786680 NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277 		JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 multiple interactions
decreases expression		 EXP Enalapril inhibits the reaction [Streptozocin results in decreased expression of NDST1 protein]; Losartan inhibits the reaction [Streptozocin results in decreased expression of NDST1 protein]
Streptozocin results in decreased expression of NDST1 mRNA; Streptozocin results in decreased expression of NDST1 protein		 CTD PMID:15793251 NCBI chr18:54,136,887...54,199,545
Ensembl chr18:54,140,779...54,178,191 		JBrowse link
G Ndufa10 NADH:ubiquinone oxidoreductase subunit A10 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of NDUFA10 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of NDUFA10 protein]		 CTD PMID:21136691 NCBI chr 9:93,007,034...93,041,825
Ensembl chr 9:93,007,042...93,042,560 		JBrowse link
G Ndufa8 NADH:ubiquinone oxidoreductase subunit A8 affects expression ISO Streptozocin affects the expression of NDUFA8 mRNA CTD PMID:18583417 NCBI chr 3:19,386,062...19,402,090
Ensembl chr 3:19,386,065...19,402,071 		JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of NDUFAB1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of NDUFAB1 protein]		 CTD PMID:19634143 NCBI chr 1:176,644,696...176,658,131
Ensembl chr 1:176,644,703...176,658,099 		JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 multiple interactions
increases expression		 EXP Trientine inhibits the reaction [Streptozocin results in increased expression of NDUFS2 protein] CTD PMID:19634143 NCBI chr13:83,654,402...83,671,474
Ensembl chr13:83,654,406...83,671,420 		JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 multiple interactions
increases expression		 EXP Trientine inhibits the reaction [Streptozocin results in increased expression of NDUFS4 protein] CTD PMID:19634143 NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846 		JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of NDUFS8 mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NDUFS8 mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NDUFS8 mRNA] CTD PMID:37337224 NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511 		JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of NDUFV2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of NDUFV2 protein]		 CTD PMID:19634143 NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:105,690,455...105,710,713 		JBrowse link
G Nefh neurofilament heavy chain decreases expression EXP Streptozocin results in decreased expression of NEFH protein CTD PMID:30583000 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351 		JBrowse link
G Nes nestin multiple interactions
decreases expression		 ISO
EXP		 INS protein inhibits the reaction [Streptozocin results in decreased expression of NES mRNA]
Streptozocin results in decreased expression of NES mRNA; Streptozocin results in decreased expression of NES protein		 CTD PMID:19388005 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777 		JBrowse link
G Neu2 neuraminidase 2 increases expression EXP Streptozocin results in increased expression of NEU2 mRNA CTD PMID:25905778 NCBI chr 9:88,218,494...88,267,356
Ensembl chr 9:88,249,135...88,267,355 		JBrowse link
G Neurod1 neuronal differentiation 1 multiple interactions
decreases expression		 ISO [Streptozocin co-treated with bisphenol A] results in decreased expression of NEUROD1 mRNA; octylphenol inhibits the reaction [Streptozocin results in decreased expression of NEUROD1 mRNA]; Streptozocin inhibits the reaction [Ethinyl Estradiol results in increased expression of NEUROD1 mRNA]; Streptozocin inhibits the reaction [octylphenol results in increased expression of NEUROD1 mRNA] CTD PMID:24781736 PMID:29935216 NCBI chr 3:64,359,554...64,363,526
Ensembl chr 3:64,359,395...64,363,649 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 increases expression
multiple interactions		 ISO Streptozocin results in increased expression of NFATC1 mRNA; Streptozocin results in increased expression of NFATC1 protein
formononetin inhibits the reaction [Streptozocin results in increased expression of NFATC1 mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of NFATC1 protein]		 CTD PMID:35315182 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases expression
increases activity
affects localization
decreases expression
affects response to substance		 EXP
ISO		 2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of NFE2L2 protein]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 protein; [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; [Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 mRNA; [Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 protein; allyl isothiocyanate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NFE2L2 protein inhibits the reaction [Streptozocin results in increased expression of USP15 protein]]; chromium histidinate inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; Curcumin inhibits the reaction [Streptozocin affects the localization of NFE2L2 protein]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; G6PD protein promotes the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; G6PD protein promotes the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 mRNA]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; NFE2L2 protein inhibits the reaction [Streptozocin results in decreased expression of G6PD mRNA]; NFE2L2 protein inhibits the reaction [Streptozocin results in decreased expression of G6PD protein]; NFE2L2 protein inhibits the reaction [Streptozocin results in increased expression of USP15 protein]; palbinone inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; picolinic acid inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; Plant Extracts inhibits the reaction [Streptozocin affects the localization of NFE2L2 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 mRNA]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; Resveratrol promotes the reaction [Streptozocin affects the localization of NFE2L2 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; USP15 protein inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; USP15 protein inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]
streptozocin increases expression of Nfe2l2 protein in heart
Streptozocin results in increased activity of NFE2L2 protein
2,5-dihydroxybenzoic acid promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NFE2L2 protein]; [Acrylamide co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 protein; [NFE2L2 protein mutant form co-treated with Streptozocin] results in increased abundance of 3-Hydroxybutyric Acid; [NFE2L2 protein mutant form co-treated with Streptozocin] results in increased abundance of Glucose; [NFE2L2 protein mutant form co-treated with Streptozocin] results in increased abundance of Triglycerides; [Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of NFE2L2 protein; [Streptozocin co-treated with sulforaphane] results in increased expression of NFE2L2; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 protein]; Metformin promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [Streptozocin results in decreased abundance of Glycogen]; pterostilbene inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; pterostilbene inhibits the reaction [Streptozocin results in decreased phosphorylation of and affects the localization of NFE2L2 protein]; Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein; Streptozocin results in decreased phosphorylation of and affects the localization of NFE2L2 protein; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 mRNA]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]
Streptozocin results in decreased expression of NFE2L2 mRNA; Streptozocin results in decreased expression of NFE2L2 protein
NFE2L2 protein affects the susceptibility to Streptozocin
Streptozocin results in increased expression of NFE2L2 mRNA; Streptozocin results in increased expression of NFE2L2 protein		 CTD
RGD		 PMID:20086057 PMID:20399799 PMID:21439372 PMID:21799698 PMID:22023613 More... RGD:156430337 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases activity
multiple interactions		 EXP Streptozocin results in increased activity of NFKB1 protein
[Dietary Fats co-treated with Streptozocin] results in increased expression of NFKB1 mRNA; [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein; Bilirubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 mRNA]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NFKB1 mRNA]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NFKB1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein]		 CTD PMID:15284299 PMID:31100278 PMID:36999408 PMID:37054934 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression
increases degradation
decreases expression
increases phosphorylation
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of NFKBIA mRNA; Streptozocin results in increased expression of NFKBIA protein
Streptozocin results in increased degradation of NFKBIA protein
Streptozocin results in decreased expression of NFKBIA mRNA
Streptozocin results in increased phosphorylation of NFKBIA protein
Streptozocin results in decreased expression of NFKBIA mRNA; Streptozocin results in decreased expression of NFKBIA protein; Streptozocin results in decreased expression of NFKBIA protein modified form
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]]; arjunolic acid inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of NFKBIA protein]; benazepril inhibits the reaction [Streptozocin results in decreased expression of NFKBIA mRNA]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]; chromium histidinate inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of NFKBIA mRNA]; fasudil inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in decreased expression of NFKBIA protein modified form]; picolinic acid inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]; Quercetin inhibits the reaction [Streptozocin results in increased degradation of NFKBIA protein]; Streptozocin promotes the reaction [IGF2R protein modified form results in decreased expression of NFKBIA protein modified form]; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of NFKBIA mRNA]		 CTD PMID:15284299 PMID:15976052 PMID:16177186 PMID:16684804 PMID:17900838 More... NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nfkbiz NFKB inhibitor zeta multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of NFKBIZ mRNA CTD PMID:25905778 NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723 		JBrowse link
G Ngf nerve growth factor multiple interactions
decreases expression
increases expression
affects localization		 EXP 4-methylcatechol inhibits the reaction [Streptozocin results in decreased expression of NGF protein]; Butylated Hydroxytoluene inhibits the reaction [Streptozocin results in increased expression of NGF mRNA]; epalrestat inhibits the reaction [Streptozocin results in decreased expression of NGF protein]; sorbinil inhibits the reaction [Streptozocin results in increased expression of NGF mRNA]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of NGF protein]
Streptozocin affects the localization of NGF protein		 CTD PMID:8195800 PMID:9628756 PMID:9748608 PMID:12031555 PMID:38049026 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nim1k NIM1 serine/threonine protein kinase multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of NIM1K mRNA CTD PMID:25905778 NCBI chr 2:51,670,764...51,714,782
Ensembl chr 2:51,670,772...51,714,762 		JBrowse link
G Nipsnap2 nipsnap homolog 2 affects expression ISO Streptozocin affects the expression of NIPSNAP2 mRNA CTD PMID:18583417 NCBI chr12:26,906,068...26,944,201
Ensembl chr12:26,911,723...26,944,166 		JBrowse link
G Nkap NFKB activating protein multiple interactions EXP Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of NKAP mRNA] CTD PMID:30611788 NCBI chr  X:116,373,031...116,392,677
Ensembl chr  X:116,372,839...116,394,945 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression		 EXP
ISO		 [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of NLRP3 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein]; myrtenol inhibits the reaction [Streptozocin results in increased expression of NLRP3 mRNA]; palbinone inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NLRP3 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein]; scutellarin inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein]
[Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 mRNA]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 protein]; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP1 protein]; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP2 protein]; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of CASP1 protein]
Streptozocin results in increased expression of NLRP3 mRNA; Streptozocin results in increased expression of NLRP3 protein		 CTD PMID:23647015 PMID:27783111 PMID:32202043 PMID:34477272 PMID:35961541 More... NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of NMRK1 mRNA
[resveratrol co-treated with Streptozocin] results in decreased expression of NMRK1 mRNA		 CTD PMID:25905778 NCBI chr 1:216,049,350...216,076,792
Ensembl chr 1:216,049,437...216,076,791 		JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase multiple interactions
increases expression		 EXP Trientine inhibits the reaction [Streptozocin results in increased expression of NNT protein] CTD PMID:19634143 NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823 		JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions
increases expression
decreases expression		 EXP
ISO		 1-hexacosanol inhibits the reaction [Streptozocin results in decreased expression of NOS1 mRNA]; 1-hexacosanol inhibits the reaction [Streptozocin results in decreased expression of NOS1 protein]; [Sildenafil Citrate co-treated with resveratrol] inhibits the reaction [Streptozocin results in decreased expression of NOS1 protein]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of NOS1 protein]
Acrylamide inhibits the reaction [Streptozocin results in increased expression of NOS1 mRNA]
Streptozocin results in decreased expression of NOS1 mRNA; Streptozocin results in decreased expression of NOS1 protein		 CTD PMID:18528636 PMID:26006044 PMID:34896238 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases activity
increases expression		 ISO
EXP		 [bisphenol A co-treated with Streptozocin] results in decreased expression of NOS2 protein; [Ethinyl Estradiol co-treated with Streptozocin] results in decreased expression of NOS2 protein; [octylphenol co-treated with Streptozocin] results in decreased expression of NOS2 protein; [Streptozocin co-treated with bisphenol A] results in increased expression of NOS2 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NOS2 mRNA; AM6545 inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]]; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NOS2 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased activity of NOS2 protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; Streptozocin inhibits the reaction [Ethinyl Estradiol results in decreased expression of NOS2 mRNA]; Streptozocin inhibits the reaction [octylphenol results in decreased expression of NOS2 mRNA]; terutroban inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]
Streptozocin results in increased expression of NOS2 mRNA; Streptozocin results in increased expression of NOS2 protein
1-hexacosanol inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; 1-hexacosanol inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; candesartan inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased activity of NOS2 protein]; Kangen-karyu inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; Metformin inhibits the reaction [Streptozocin results in increased activity of NOS2 protein]; Metoprolol inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]]		 CTD PMID:15821039 PMID:16139267 PMID:16177186 PMID:16309587 PMID:16380483 More... NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
decreases expression
decreases phosphorylation
increases expression		 EXP 1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]]; 1-hexacosanol inhibits the reaction [Streptozocin results in decreased expression of NOS3 protein]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; [Sildenafil Citrate co-treated with Resveratrol] inhibits the reaction [Streptozocin results in decreased expression of NOS3 protein]; [Streptozocin co-treated with Dietary Fats] results in decreased expression of NOS3 mRNA; Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; Allopurinol inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]]; Atorvastatin inhibits the reaction [Streptozocin results in decreased expression of NOS3 protein]; candesartan inhibits the reaction [Streptozocin results in increased expression of NOS3 mRNA]; candesartan inhibits the reaction [Streptozocin results in increased expression of NOS3 protein]; Cholesterol, Dietary inhibits the reaction [Streptozocin results in increased expression of NOS3 protein]; cloricromen inhibits the reaction [Streptozocin results in increased expression of NOS3 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NOS3 mRNA]; Resveratrol inhibits the reaction [Streptozocin promotes the reaction [CAV1 protein binds to NOS3 protein]]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of NOS3 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of NOS3 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of NOS3 mRNA]; Streptozocin promotes the reaction [CAV1 protein binds to NOS3 protein]; Streptozocin results in decreased activity of and results in decreased phosphorylation of NOS3 protein
Streptozocin results in decreased expression of NOS3 mRNA; Streptozocin results in decreased expression of NOS3 protein
Streptozocin results in increased expression of NOS3 mRNA; Streptozocin results in increased expression of NOS3 protein		 CTD PMID:11696579 PMID:12377873 PMID:14871415 PMID:16045816 PMID:16139267 More... NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions
increases expression		 EXP
ISO		 [Resveratrol co-treated with Streptozocin] results in decreased expression of NOX4 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NOX4 protein; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of NOX4 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NOX4 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of NOX4 mRNA]
[Streptozocin co-treated with Dietary Fats] results in decreased expression of NOX4 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NOX4 protein; aucubin inhibits the reaction [Streptozocin results in increased expression of NOX4 protein]		 CTD PMID:16979161 PMID:25905778 PMID:29127188 PMID:35085591 PMID:35961541 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Npas2 neuronal PAS domain protein 2 decreases expression EXP Streptozocin results in decreased expression of NPAS2 mRNA CTD PMID:25905778 NCBI chr 9:41,463,361...41,642,322
Ensembl chr 9:41,463,830...41,642,320 		JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin decreases expression
multiple interactions
increases secretion		 EXP
ISO		 Streptozotocin decreases expression of Nphs1 mRNA and protein in kidney
[Streptozocin co-treated with Fructose] results in decreased expression of NPHS1 mRNA; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in decreased expression of NPHS1 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in decreased expression of NPHS1 mRNA]; Mycophenolic Acid inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]; Mycophenolic Acid inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of NPHS1 mRNA]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of NPHS1 protein]; stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased secretion of NPHS1 protein]]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein]
Streptozocin results in decreased expression of NPHS1 mRNA; Streptozocin results in decreased expression of NPHS1 protein
AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]; AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein]]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein]]
streptozotocin decreases expression of Nphs1 protein in kidney
Streptozocin decreases expression of Nphs1 mRNA in kidney
Streptozotocin decreases expression of Nphs1 mRNA and protein in renal glomerulus		 CTD
RGD		 PMID:17624267 PMID:20547220 PMID:23611540 PMID:25199697 PMID:30184259 More... RGD:38596322, RGD:7241083, RGD:38599008, RGD:38596325 NCBI chr 1:85,720,812...85,749,079
Ensembl chr 1:85,720,812...85,749,078 		JBrowse link
G Nphs2 NPHS2 stomatin family member, podocin multiple interactions
decreases expression		 EXP
ISO		 Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of NPHS2 mRNA]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of NPHS2 protein]
AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]; AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]]
Streptozocin results in decreased expression of NPHS2 mRNA; Streptozocin results in decreased expression of NPHS2 protein		 CTD PMID:20547220 PMID:25199697 PMID:30184259 NCBI chr13:68,448,720...68,461,312
Ensembl chr13:68,448,926...68,461,313 		JBrowse link
G Nppa natriuretic peptide A increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of NPPA mRNA; Streptozocin results in increased expression of NPPA protein
Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of NPPA protein]
SLC25A4 protein inhibits the reaction [Streptozocin results in increased expression of NPPA mRNA]		 CTD PMID:16409969 PMID:16980342 PMID:18945756 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Nppb natriuretic peptide B increases expression
multiple interactions		 EXP Streptozocin results in increased expression of NPPB mRNA
[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of NPPB protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of NPPB protein]		 CTD PMID:10828832 PMID:34801538 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168 		JBrowse link
G Nppc natriuretic peptide C decreases expression EXP Streptozocin results in decreased expression of NPPC mRNA CTD PMID:10828832 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251 		JBrowse link
G Npy neuropeptide Y multiple interactions
increases expression		 EXP INS protein inhibits the reaction [Streptozocin results in increased expression of NPY mRNA] CTD PMID:20219977 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
decreases expression
increases expression
affects response to substance		 EXP
ISO		 diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of NQO1 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA]; Metformin inhibits the reaction [Streptozocin results in decreased expression of NQO1 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA]
2,5-dihydroxybenzoic acid promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NQO1 mRNA]; [omaveloxolone analog co-treated with Streptozocin co-treated with Dietary Fats] results in increased activity of NQO1 protein; [omaveloxolone co-treated with Streptozocin co-treated with Dietary Fats] results in increased activity of NQO1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of NQO1 mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of NQO1 mRNA; [Streptozocin co-treated with NQO1 protein mutant form] results in increased expression of AIFM1 protein; [Streptozocin co-treated with NQO1 protein mutant form] results in increased expression of CASP3 protein modified form; [Streptozocin co-treated with NQO1 protein mutant form] results in increased secretion of DIABLO protein; [Streptozocin co-treated with sulforaphane] results in increased expression of NQO1; Metformin promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NQO1 mRNA]; omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NQO1 mRNA]; omaveloxolone promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NQO1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NQO1 protein]
Streptozocin results in increased expression of NQO1 mRNA
NQO1 protein affects the susceptibility to Streptozocin
Streptozocin results in decreased expression of NQO1 mRNA; Streptozocin results in decreased expression of NQO1 protein		 CTD PMID:21457706 PMID:22023613 PMID:22531820 PMID:23319174 PMID:23458895 More... NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions EXP
ISO		 [resveratrol co-treated with Streptozocin] results in increased expression of NR0B2 mRNA
[Dietary Fats co-treated with Streptozocin] results in increased expression of NR0B2 protein		 CTD PMID:25905778 PMID:29382564 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 decreases expression EXP Streptozocin results in decreased expression of NR1D1 mRNA CTD PMID:25905778 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of NR1H2 protein
[homocastasterone analog co-treated with Streptozocin] results in increased expression of NR1H2 mRNA; homocastasterone analog inhibits the reaction [Streptozocin results in decreased expression of NR1H2 protein]		 CTD PMID:28822685 NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions
increases expression 		EXP [homocastasterone analog co-treated with Streptozocin] results in increased expression of NR1H3 mRNA; [homocastasterone analog co-treated with Streptozocin] results in increased expression of NR1H3 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of NR1H3 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of NR1H3 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NR1H3 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NR1H3 protein]
Streptozotocin increases expression of Nr1h3 mRNA and protein in the heart
Streptozocin results in increased expression of NR1H3 mRNA; Streptozocin results in increased expression of NR1H3 protein		 CTD
RGD		 PMID:23647015 PMID:28822685 PMID:21136146 RGD:13831298 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of NR1H4 protein CTD PMID:29382564 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of NT5E mRNA CTD PMID:29127188 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881 		JBrowse link
G Ntf3 neurotrophin 3 affects localization EXP Streptozocin affects the localization of NTF3 protein CTD PMID:12031555 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596 		JBrowse link
G Ntn1 netrin 1 decreases expression
multiple interactions		 ISO Streptozocin results in decreased expression of NTN1 protein
[NTN1 protein co-treated with Streptozocin] results in increased expression of ARG1 protein; NTN1 protein inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN2A mRNA]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN2A protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of RELA protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53 mRNA]; NTN1 protein promotes the reaction [Streptozocin results in increased expression of DCC mRNA]; NTN1 protein promotes the reaction [Streptozocin results in increased expression of DCC protein]; Streptozocin promotes the reaction [NTN1 protein results in increased phosphorylation of MAPK1 protein]; Streptozocin promotes the reaction [NTN1 protein results in increased phosphorylation of MAPK3 protein]		 CTD PMID:29059224 NCBI chr10:52,899,933...53,098,591
Ensembl chr10:52,899,934...53,085,326 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of NTRK1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NTRK1 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NTRK1 mRNA] CTD PMID:33484791 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 decreases phosphorylation
decreases expression
multiple interactions		 ISO
EXP		 Streptozocin results in decreased phosphorylation of NTRK2 protein
Streptozocin results in decreased expression of NTRK2 mRNA
Metformin inhibits the reaction [Streptozocin results in increased expression of NTRK2 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of NTRK2 mRNA]
Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of NTRK2 protein]; Physostigmine inhibits the reaction [Streptozocin results in decreased phosphorylation of NTRK2 protein]		 CTD PMID:28499986 PMID:35414346 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Nudt7 nudix hydrolase 7 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of NUDT7 mRNA CTD PMID:29127188 NCBI chr19:42,125,679...42,151,198
Ensembl chr19:42,125,711...42,151,081 		JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of NUS1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of NUS1 protein; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of MFN2 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARGC1A mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SIRT1 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of GSK3B protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ACACA mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF4 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF6 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of DGAT1 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of EIF2AK3 protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GK mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of INPP5K mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of EIF2S1 protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased splicing of XBP1 mRNA] CTD PMID:33812996 NCBI chr20:31,811,817...31,838,562
Ensembl chr20:31,811,817...31,838,561 		JBrowse link
G Nyap1 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of NYAP1 mRNA CTD PMID:33484791 NCBI chr12:18,956,192...18,967,624
Ensembl chr12:18,956,268...18,967,543 		JBrowse link
G Oat ornithine aminotransferase decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of OAT protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of OAT protein]		 CTD PMID:19634143 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682 		JBrowse link
G Ocln occludin decreases expression
multiple interactions		 ISO Streptozocin results in decreased expression of OCLN protein
rhodioloside inhibits the reaction [Streptozocin results in decreased expression of OCLN protein]		 CTD PMID:31682803 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Oga O-GlcNAcase multiple interactions ISO
EXP		 Streptozocin binds to and results in decreased activity of OGA protein
[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of OGA protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of OGA protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of OGA protein]		 CTD PMID:18721751 PMID:30551545 NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359 		JBrowse link
G Ogdh oxoglutarate dehydrogenase multiple interactions
increases expression		 EXP Trientine inhibits the reaction [Streptozocin results in increased expression of OGDH protein] CTD PMID:19634143 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479 		JBrowse link
G Olr59 olfactory receptor 59 decreases expression EXP Streptozocin results in decreased expression of OLR59 mRNA CTD PMID:25905778 NCBI chr 1:157,193,051...157,227,707
Ensembl chr 1:157,193,080...157,211,179 		JBrowse link
G Opn4 opsin 4 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of OPN4 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of OPN4 mRNA] CTD PMID:33484791 NCBI chr16:9,920,408...9,929,580
Ensembl chr16:9,920,491...10,005,711 		JBrowse link
G Orm1 orosomucoid 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of ORM1 mRNA CTD PMID:25905778 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154 		JBrowse link
G P2rx2 purinergic receptor P2X 2 increases expression ISO Streptozocin results in increased expression of P2RX2 mRNA CTD PMID:19383439 NCBI chr12:46,338,979...46,342,891
Ensembl chr12:46,339,549...46,342,891 		JBrowse link
G P2rx3 purinergic receptor P2X 3 increases expression ISO Streptozocin results in increased expression of P2RX3 mRNA CTD PMID:19383439 NCBI chr 3:70,080,850...70,124,664
Ensembl chr 3:70,080,851...70,125,178 		JBrowse link
G Pabpc1l poly(A) binding protein, cytoplasmic 1-like multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of PABPC1L mRNA CTD PMID:33484791 NCBI chr 3:152,692,825...152,725,997
Ensembl chr 3:152,693,700...152,725,997 		JBrowse link
G Pah phenylalanine hydroxylase multiple interactions
increases expression
increases activity		 EXP peroxovanadate inhibits the reaction [Streptozocin results in increased activity of PAH protein]; peroxovanadate inhibits the reaction [Streptozocin results in increased expression of PAH mRNA] CTD PMID:11055810 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of PAK1 mRNA CTD PMID:29127188 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383 		JBrowse link
G Parg poly (ADP-ribose) glycohydrolase increases response to substance ISO PARG gene mutant form results in increased susceptibility to Streptozocin CTD PMID:15282315 NCBI chr16:7,436,429...7,544,276
Ensembl chr16:7,436,476...7,544,273 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
increases activity		 EXP
ISO		 Streptozocin results in increased cleavage of PARP1 protein
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin results in increased activity of PARP1 protein]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to PARP1 protein]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [PARP1 protein binds to MMP9 promoter]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [RELA protein binds to PARP1 protein]]; Streptozocin promotes the reaction [JUN protein binds to PARP1 protein]; Streptozocin promotes the reaction [PARP1 protein binds to MMP9 promoter]; Streptozocin promotes the reaction [RELA protein binds to PARP1 protein]
Anthocyanins inhibits the reaction [Streptozocin results in increased cleavage of PARP1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of PARP1 protein]		 CTD PMID:25541178 PMID:27288104 PMID:28478229 PMID:28856781 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pax8 paired box 8 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of PAX8 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of PAX8 mRNA] CTD PMID:32303808 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363 		JBrowse link
G Pc pyruvate carboxylase increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of PC protein
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PCX protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of PCX protein
Trientine inhibits the reaction [Streptozocin results in increased expression of PC protein]		 CTD PMID:19634143 PMID:25446853 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions
increases expression		 EXP
ISO		 bis(maltolato)oxovanadium(IV) inhibits the reaction [Streptozocin results in increased expression of PCK1 mRNA]; cinnamaldehyde inhibits the reaction [Streptozocin results in increased expression of PCK1 mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of PCK1 mRNA]; Trientine inhibits the reaction [Streptozocin results in increased expression of PCK1 protein]
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PCK1 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of PCK1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of PCK1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of PCK1 mRNA]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PCK1 mRNA]
Streptozocin results in increased expression of PCK1 mRNA; Streptozocin results in increased expression of PCK1 protein		 CTD PMID:12446591 PMID:19634143 PMID:20363216 PMID:25446853 PMID:26522834 More... NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) multiple interactions
increases expression		 EXP Tribulus extract inhibits the reaction [Streptozocin results in increased expression of PCK2 protein] CTD PMID:36627075 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP
ISO		 [Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of PCNA protein
[Streptozocin co-treated with Dextran Sulfate] results in increased expression of PCNA protein		 CTD PMID:30421503 PMID:34964214 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of PCSK1 mRNA CTD PMID:25905778 NCBI chr 2:4,395,543...4,442,434
Ensembl chr 2:4,395,543...4,442,434 		JBrowse link
G Pde4b phosphodiesterase 4B decreases expression EXP Streptozocin results in decreased expression of PDE4B mRNA CTD PMID:25905778 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
G Pde5a phosphodiesterase 5A multiple interactions
increases expression		 EXP [Sildenafil Citrate co-treated with Resveratrol] inhibits the reaction [Streptozocin results in increased expression of PDE5A protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of PDE5A protein]
Streptozocin results in increased expression of PDE5A mRNA; Streptozocin results in increased expression of PDE5A protein		 CTD PMID:26006044 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701 		JBrowse link
G Pde6c phosphodiesterase 6C multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of PDE6C mRNA CTD PMID:33484791 NCBI chr 1:235,909,583...235,965,435
Ensembl chr 1:235,909,775...235,965,315 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha decreases expression ISO Streptozocin results in decreased expression of PDGFRA mRNA CTD PMID:26073000 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pdgfrl platelet-derived growth factor receptor-like multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of PDGFRL mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PDGFRL mRNA] CTD PMID:33484791 NCBI chr16:51,347,929...51,407,850
Ensembl chr16:51,347,948...51,407,850 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PDK1 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of PDK1 mRNA CTD PMID:25446853 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 decreases expression
multiple interactions		 ISO Streptozocin results in decreased expression of PDX1 mRNA
[Dietary Fats co-treated with Streptozocin] results in decreased expression of PDX1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PDX1 protein; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PDX1 mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PDX1 protein]; octylphenol inhibits the reaction [Streptozocin results in decreased expression of PDX1 mRNA]		 CTD PMID:24781736 PMID:29935216 PMID:33359794 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064 		JBrowse link
G Pdxp pyridoxal phosphatase multiple interactions
increases expression		 EXP [resveratrol co-treated with Streptozocin] results in decreased expression of PDXP mRNA
Streptozocin results in increased expression of PDXP mRNA		 CTD PMID:25905778 NCBI chr 7:110,472,515...110,477,963
Ensembl chr 7:110,472,515...110,477,963 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of PECAM1 protein; Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PECAM1 protein]; sarpogrelate inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PECAM1 protein] CTD PMID:27097221 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase increases activity
affects expression		 EXP
ISO		 Streptozocin results in increased activity of PEMT protein
Streptozocin affects the expression of PEMT mRNA		 CTD PMID:16835399 PMID:18583417 NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013 		JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 increases expression EXP Streptozocin results in increased expression of PFKFB1 mRNA CTD PMID:25905778 NCBI chr  X:19,508,522...19,562,165
Ensembl chr  X:19,508,546...19,562,182 		JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 multiple interactions
decreases activity		 EXP Lithium Carbonate inhibits the reaction [Streptozocin results in decreased activity of PFKFB2 protein] CTD PMID:10700396 NCBI chr13:42,147,473...42,174,699
Ensembl chr13:42,147,478...42,174,699 		JBrowse link
G Pfkp phosphofructokinase, platelet multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PFKP protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PFKP protein CTD PMID:25446853 NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018 		JBrowse link
G Phactr3 phosphatase and actin regulator 3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of PHACTR3 mRNA CTD PMID:33484791 NCBI chr 3:165,205,247...165,423,692
Ensembl chr 3:165,205,255...165,423,153 		JBrowse link
G Phb1 prohibitin 1 decreases expression EXP Streptozocin results in decreased expression of PHB1 protein CTD PMID:21136691 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha multiple interactions ISO streptozocin decreases expression and increases phosphorylation of Pik3ca in cardiac muscle cells RGD PMID:36044268 RGD:156430337 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in decreased expression of PIK3CB mRNA
[Streptozocin co-treated with Dietary Fats] results in decreased expression of PIK3CB protein; Dibutyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PIK3CB protein]; L 783281 inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PIK3CB protein]; L 783281 inhibits the reaction [Dibutyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PIK3CB protein]]
resveratrol inhibits the reaction [Streptozocin results in decreased expression of PIK3CB mRNA]		 CTD PMID:26071184 PMID:29526571 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions
decreases expression		 EXP
ISO		 Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of PIK3R1 mRNA]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of PIK3R1 mRNA]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of PIK3R1 mRNA]]
[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of PIK3R1 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of PIK3R1 protein]		 CTD PMID:32805344 PMID:33484791 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of PINK1 mRNA CTD PMID:33812996 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Pitpnc1 phosphatidylinositol transfer protein, cytoplasmic 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of PITPNC1 mRNA CTD PMID:20665664 NCBI chr10:92,163,558...92,428,971
Ensembl chr10:92,167,196...92,429,297 		JBrowse link
G Pklr pyruvate kinase L/R multiple interactions
decreases expression		 EXP
ISO		 cinnamaldehyde inhibits the reaction [Streptozocin results in decreased expression of PKLR mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of PKLR mRNA]
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PKLR protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PKLR protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PKLR mRNA; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PKLR mRNA]		 CTD PMID:20363216 PMID:25446853 PMID:26522834 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870 		JBrowse link
G Pkm pyruvate kinase M1/2 affects expression ISO Streptozocin affects the expression of PKM mRNA CTD PMID:18583417 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599 		JBrowse link
G Pla2g7 phospholipase A2 group VII multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of PLA2G7 mRNA CTD PMID:29127188 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476 		JBrowse link
G Plaat3 phospholipase A and acyltransferase 3 multiple interactions EXP [Resveratrol co-treated with Streptozocin] results in increased expression of PLAAT3 mRNA CTD PMID:25905778 NCBI chr 1:204,782,608...204,816,397
Ensembl chr 1:204,782,729...204,817,667 		JBrowse link
G Plau plasminogen activator, urokinase increases expression
multiple interactions		 EXP Streptozocin results in increased expression of PLAU mRNA; Streptozocin results in increased expression of PLAU protein
[resveratrol co-treated with Streptozocin] results in increased expression of PLAU mRNA; benazepril inhibits the reaction [Streptozocin results in increased expression of PLAU mRNA]		 CTD PMID:15322501 PMID:25905778 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plaur plasminogen activator, urokinase receptor increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of PLAUR mRNA; Streptozocin results in increased expression of PLAUR protein
[Streptozocin co-treated with Dietary Fats] results in increased expression of PLAUR mRNA
benazepril inhibits the reaction [Streptozocin results in increased expression of PLAUR mRNA]		 CTD PMID:15322501 PMID:29127188 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Plcb1 phospholipase C beta 1 multiple interactions
increases expression		 EXP acetovanillone inhibits the reaction [Streptozocin results in increased expression of PLCB1 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of PLCB1 protein] CTD PMID:20691780 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Plcb2 phospholipase C, beta 2 multiple interactions
increases expression		 EXP acetovanillone inhibits the reaction [Streptozocin results in increased expression of PLCB2 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of PLCB2 protein] CTD PMID:20691780 NCBI chr 3:105,683,676...105,704,384
Ensembl chr 3:105,684,815...105,704,302 		JBrowse link
G Plch1 phospholipase C, eta 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of PLCH1 mRNA CTD PMID:33484791 NCBI chr 2:148,148,908...148,363,616
Ensembl chr 2:148,148,921...148,364,097 		JBrowse link
G Plin2 perilipin 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of PLIN2 mRNA CTD PMID:25905778 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319 		JBrowse link
G Plscr1 phospholipid scramblase 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of PLSCR1 mRNA CTD PMID:25905778 NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692 		JBrowse link
G Pmp22 peripheral myelin protein 22 multiple interactions
decreases expression		 EXP Progesterone inhibits the reaction [Streptozocin results in decreased expression of PMP22 mRNA] CTD PMID:17187935 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714 		JBrowse link
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 affects expression ISO Streptozocin affects the expression of PNPT1 mRNA CTD PMID:18583417 NCBI chr14:102,877,553...102,908,696
Ensembl chr14:102,877,553...102,908,696 		JBrowse link
G Polg DNA polymerase gamma, catalytic subunit affects expression ISO Streptozocin affects the expression of POLG mRNA CTD PMID:18583417 NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567 		JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit affects expression ISO Streptozocin affects the expression of POLG2 mRNA CTD PMID:18583417 NCBI chr10:91,712,586...91,723,008
Ensembl chr10:91,712,586...91,723,008 		JBrowse link
G Pomc proopiomelanocortin multiple interactions
decreases expression		 EXP INS protein inhibits the reaction [Streptozocin results in decreased expression of POMC mRNA] CTD PMID:20219977 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Pon1 paraoxonase 1 multiple interactions
decreases activity
decreases expression		 EXP [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in decreased expression of PON1 mRNA; [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in decreased expression of PON1 protein; [Propolis co-treated with Streptozocin] results in decreased expression of PON1 protein; [Streptozocin co-treated with Chlorpyrifos] inhibits the reaction [Propolis results in increased expression of PON1 mRNA]; [Streptozocin co-treated with Chlorpyrifos] inhibits the reaction [Propolis results in increased expression of PON1 protein]; [Streptozocin co-treated with Chlorpyrifos] results in decreased expression of PON1 mRNA; [Streptozocin co-treated with Chlorpyrifos] results in decreased expression of PON1 protein; Chlorpyrifos inhibits the reaction [Streptozocin results in decreased expression of PON1 protein]; Chlorpyrifos promotes the reaction [Streptozocin results in decreased expression of PON1 mRNA]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in decreased expression of PON1 mRNA]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in decreased expression of PON1 protein]; Propolis inhibits the reaction [Streptozocin results in decreased expression of PON1 mRNA]; Propolis inhibits the reaction [Streptozocin results in decreased expression of PON1 protein]; Streptozocin inhibits the reaction [Chlorpyrifos results in decreased expression of PON1 protein]; Streptozocin inhibits the reaction [Propolis results in increased expression of PON1 mRNA]; Streptozocin inhibits the reaction [Propolis results in increased expression of PON1 protein]; Streptozocin promotes the reaction [Chlorpyrifos results in decreased expression of PON1 mRNA]
Streptozocin results in decreased activity of PON1 protein
Streptozocin results in decreased expression of PON1 mRNA; Streptozocin results in decreased expression of PON1 protein		 CTD PMID:31400774 PMID:34039237 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP Streptozocin results in increased expression of POR mRNA CTD PMID:25905778 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 increases expression
multiple interactions		 ISO Streptozocin results in increased expression of POU1F1 mRNA; Streptozocin results in increased expression of POU1F1 protein
INS1 protein inhibits the reaction [Streptozocin results in increased expression of POU1F1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of POU1F1 protein]		 CTD PMID:29216956 NCBI chr11:3,316,818...3,334,804
Ensembl chr11:3,317,058...3,334,801 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions EXP [bisphenol A co-treated with Streptozocin] results in decreased expression of POU5F1 protein CTD PMID:35187753 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects response to substance
increases expression
decreases expression
multiple interactions		 ISO
EXP		 PPARA protein affects the susceptibility to Streptozocin
Streptozocin results in increased expression of PPARA mRNA
Streptozocin results in increased expression of PPARA protein
Streptozocin results in decreased expression of PPARA mRNA; Streptozocin results in decreased expression of PPARA protein
[[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of PPARA mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA protein; [Streptozocin co-treated with Cadmium] results in decreased expression of PPARA protein; Allopurinol inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA]; Allopurinol inhibits the reaction [Streptozocin results in decreased expression of PPARA protein]; Bezafibrate inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA]; idebenone inhibits the reaction [Streptozocin results in increased expression of PPARA protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of PPARA protein]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA mRNA]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA protein]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of PPARA protein]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA mRNA; [Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARA protein; Acrylamide inhibits the reaction [Streptozocin results in increased expression of PPARA mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA mRNA]; Metformin inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA]; naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARA protein]; puerarin inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA]		 CTD PMID:12967931 PMID:16306367 PMID:23647015 PMID:23927877 PMID:25240712 More... NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in decreased expression of PPARD mRNA
[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARB protein; naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARB protein]
olive oil inhibits the reaction [Streptozocin results in decreased expression of PPARD mRNA]		 CTD PMID:25246140 PMID:31063766 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
decreases expression
increases expression		 ISO
EXP		 [Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARG mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of PPARG mRNA; [Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARG protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of PPARG protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG protein; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PPARG mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARG mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARG protein]; Telmisartan inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]
Streptozocin results in decreased expression of PPARG; Streptozocin results in decreased expression of PPARG mRNA; Streptozocin results in decreased expression of PPARG protein
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]]; 2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein]; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG protein; [Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of PPARG protein; allyl isothiocyanate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG protein]; Bezafibrate inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; chebulagic acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG protein]; esculetin inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; esculetin inhibits the reaction [Streptozocin results in increased expression of PPARG protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of PPARG protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein]; INS protein promotes the reaction [Streptozocin results in increased expression of PPARG mRNA]; mangiferin inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; mangiferin inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; naringenin inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; naringenin inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; Olive Oil inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of PPARG protein]; Rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of PPARG]
Streptozocin results in increased expression of PPARG mRNA; Streptozocin results in increased expression of PPARG protein		 CTD PMID:12967931 PMID:16980342 PMID:20219977 PMID:21381899 PMID:21450970 More... NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression
multiple interactions
increases expression		 ISO
EXP		 Streptozocin results in decreased expression of PPARGC1A protein
ferulic acid inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein]; Olive Oil inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A mRNA]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein]
Streptozocin results in decreased expression of PPARGC1A mRNA; Streptozocin results in decreased expression of PPARGC1A protein
Streptozocin results in increased expression of PPARGC1A mRNA
[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARGC1A mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of PPARGC1A mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARGC1A mRNA]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PPARGC1A mRNA]; Telmisartan inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein]		 CTD PMID:21381899 PMID:23319174 PMID:25246140 PMID:26522834 PMID:31029786 More... NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Ppfia3 PTPRF interacting protein alpha 3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of PPFIA3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PPFIA3 mRNA] CTD PMID:33484791 NCBI chr 1:95,817,110...95,845,950
Ensembl chr 1:95,817,110...95,845,798 		JBrowse link
G Ppid peptidylprolyl isomerase D increases expression
multiple interactions		 EXP Streptozocin results in increased expression of PPID protein
Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of PPID protein]		 CTD PMID:34455488 NCBI chr 2:164,727,803...164,740,168
Ensembl chr 2:164,727,779...164,740,221 		JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A multiple interactions
increases expression		 EXP [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of PPP1R12A protein; Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [Streptozocin results in increased expression of PPP1R12A protein modified form]; fasudil inhibits the reaction [Streptozocin results in increased expression of PPP1R12A protein modified form] CTD PMID:20665664 PMID:22429817 NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425 		JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C decreases expression EXP Streptozocin results in decreased expression of PPP1R3C mRNA CTD PMID:25905778 NCBI chr 1:234,460,958...234,465,961
Ensembl chr 1:234,460,652...234,465,961 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha multiple interactions
decreases expression
decreases methylation		 ISO 5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of PPP2CA protein modified form]; Folic Acid deficiency promotes the reaction [Streptozocin results in decreased methylation of PPP2CA protein]; Folic Acid inhibits the reaction [Streptozocin results in decreased methylation of PPP2CA protein]; INS1 protein affects the reaction [Streptozocin results in decreased methylation of PPP2CA protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of PPP2CA protein modified form] CTD PMID:28422052 PMID:34428446 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Ppy pancreatic polypeptide multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of PPY mRNA CTD PMID:33484791 NCBI chr10:87,054,747...87,056,044
Ensembl chr10:87,054,756...87,055,455 		JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions
decreases expression		 ISO PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX1 mRNA] CTD PMID:20446767 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Prdx2 peroxiredoxin 2 decreases expression
multiple interactions		 ISO Streptozocin results in decreased expression of PRDX2 mRNA
PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX2 mRNA]		 CTD PMID:20446767 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Prdx3 peroxiredoxin 3 multiple interactions
decreases expression		 ISO PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX3 mRNA] CTD PMID:20446767 NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111 		JBrowse link
G Prdx4 peroxiredoxin 4 multiple interactions
decreases expression		 ISO PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX1 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX2 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX3 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX4 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX5 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX6 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP3 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP7 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of PRDX4 mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PRDX4 mRNA]		 CTD PMID:20446767 PMID:33359794 NCBI chr  X:40,026,762...40,044,066
Ensembl chr  X:40,026,651...40,044,066 		JBrowse link
G Prdx5 peroxiredoxin 5 decreases expression
multiple interactions		 ISO Streptozocin results in decreased expression of PRDX5 mRNA
PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX5 mRNA]		 CTD PMID:20446767 NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268 		JBrowse link
G Prdx6 peroxiredoxin 6 multiple interactions
decreases expression		 ISO PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX6 mRNA] CTD PMID:20446767 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions EXP
ISO		 Streptozocin results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein]
[Streptozocin co-treated with Dietary Fats] results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA1 mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA1 mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA1 mRNA]		 CTD PMID:35442559 PMID:37337224 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions EXP
ISO		 streptozocin decreases expression and phosphorylation of Prkaa2 protein in liver
[Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA2 mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA2 mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA2 mRNA]		 CTD
RGD		 PMID:37337224 PMID:32535406 RGD:401850547 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of PRKACA protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of PRKACA protein] CTD PMID:32303808 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prkca protein kinase C, alpha multiple interactions
increases expression		 EXP Ethanol inhibits the reaction [Streptozocin results in increased expression of PRKCA protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of PRKCA protein] CTD PMID:12198386 PMID:25199697 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Prkcb protein kinase C, beta increases phosphorylation EXP Streptozocin results in increased phosphorylation of PRKCB protein CTD PMID:16980342 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536 		JBrowse link
G Prkcd protein kinase C, delta multiple interactions
increases expression		 EXP arjunolic acid inhibits the reaction [Streptozocin results in increased expression of PRKCD protein]; Ethanol inhibits the reaction [Streptozocin results in increased expression of PRKCD protein] CTD PMID:12198386 PMID:19682444 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prkce protein kinase C, epsilon multiple interactions
increases expression		 EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of PRKCE mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of PRKCE protein; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of PRKCE protein]; Ethanol inhibits the reaction [Streptozocin results in increased expression of PRKCE protein] CTD PMID:12198386 PMID:19682444 PMID:20665664 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 decreases expression
multiple interactions		 ISO Streptozocin results in decreased expression of PRKG1 protein
5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of PRKG1 protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of PRKG1 protein]		 CTD PMID:34428446 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
G Prkg2 protein kinase cGMP-dependent 2 multiple interactions ISO [ALPK1 protein results in increased susceptibility to Streptozocin] which results in decreased expression of PRKG2 mRNA CTD PMID:27542954 NCBI chr14:10,559,882...10,668,479
Ensembl chr14:10,559,882...10,666,888 		JBrowse link
G Prok1 prokineticin 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of PROK1 mRNA CTD PMID:29127188 NCBI chr 2:194,850,539...194,859,343
Ensembl chr 2:194,853,991...194,859,250 		JBrowse link
G Prok2 prokineticin 2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of PROK2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PROK2 mRNA] CTD PMID:33484791 NCBI chr 4:132,346,681...132,361,754
Ensembl chr 4:132,347,103...132,361,385 		JBrowse link
G Prph peripherin decreases expression EXP Streptozocin results in decreased expression of PRPH protein CTD PMID:30583000 NCBI chr 7:130,218,149...130,222,136
Ensembl chr 7:130,218,357...130,222,136 		JBrowse link
G Prss1 serine protease 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of PRSS1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PRSS1 mRNA] CTD PMID:33484791 NCBI chr 4:70,364,589...70,367,792
Ensembl chr 4:70,364,586...70,367,792 		JBrowse link
G Prtn3 proteinase 3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of PRTN3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PRTN3 mRNA] CTD PMID:33484791 NCBI chr 7:9,822,123...9,831,300
Ensembl chr 7:9,822,122...9,831,944 		JBrowse link
G Psd2 pleckstrin and Sec7 domain containing 2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of PSD2 mRNA CTD PMID:33484791 NCBI chr18:27,564,912...27,616,674
Ensembl chr18:27,565,587...27,616,672 		JBrowse link
G Psrc1 proline and serine rich coiled-coil 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of PSRC1 mRNA CTD PMID:29127188 NCBI chr 2:196,022,361...196,026,874
Ensembl chr 2:196,022,361...196,026,874 		JBrowse link
G Pten phosphatase and tensin homolog increases expression
multiple interactions		 EXP Streptozocin results in increased expression of PTEN mRNA
Phycocyanin inhibits the reaction [Streptozocin results in increased expression of PTEN mRNA]; Rivastigmine inhibits the reaction [Streptozocin results in increased expression of PTEN mRNA]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in increased expression of PTEN mRNA]]		 CTD PMID:32805344 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions
increases expression		 EXP [resveratrol co-treated with Streptozocin] results in increased expression of PTGS1 mRNA; acetovanillone inhibits the reaction [Streptozocin results in increased expression of PTGS1 protein] CTD PMID:12888618 PMID:18414395 PMID:25905778 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases activity
increases expression		 EXP
ISO		 [1-((4-methylsulfonyl)phenyl)-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole binds to and results in decreased activity of PTGS2 protein] which results in decreased susceptibility to Streptozocin; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide binds to and results in decreased activity of PTGS2 protein] which results in decreased susceptibility to Streptozocin; [Telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; acetovanillone inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of PTGS2 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA]; Kangen-karyu inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA]
Streptozocin results in increased activity of PTGS2 protein
Acrylamide promotes the reaction [Streptozocin results in increased expression of PTGS2 protein]; asiatic acid inhibits the reaction [Streptozocin results in increased activity of PTGS2 protein]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Streptozocin results in increased activity of PTGS2 protein]]; Carnosine inhibits the reaction [Streptozocin results in increased activity of PTGS2 protein]; Carnosine promotes the reaction [asiatic acid inhibits the reaction [Streptozocin results in increased activity of PTGS2 protein]]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]
Streptozocin results in increased expression of PTGS2 mRNA; Streptozocin results in increased expression of PTGS2 protein		 CTD PMID:12888618 PMID:14514642 PMID:17112505 PMID:18414395 PMID:19397970 More... NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 multiple interactions
increases expression		 ISO resveratrol inhibits the reaction [Streptozocin results in increased expression of PTPN1 protein] CTD PMID:25808216 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Ptprd protein tyrosine phosphatase, receptor type, D multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of PTPRD mRNA CTD PMID:20665664 NCBI chr 5:90,046,993...90,698,977
NCBI chr 5:91,122,354...91,641,754
Ensembl chr 5:90,048,966...92,369,396 		JBrowse link
G Ptprm protein tyrosine phosphatase, receptor type, M multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of PTPRM mRNA CTD PMID:20665664 NCBI chr 9:106,639,573...107,343,698
Ensembl chr 9:106,639,573...107,343,698 		JBrowse link
G Ptprt protein tyrosine phosphatase, receptor type, T multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of PTPRT mRNA CTD PMID:20665664 NCBI chr 3:150,189,343...151,288,145
Ensembl chr 3:150,194,859...151,288,124 		JBrowse link
G Pycard PYD and CARD domain containing multiple interactions
increases expression		 EXP
ISO		 Allopurinol inhibits the reaction [Streptozocin results in increased expression of PYCARD mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of PYCARD protein]; palbinone inhibits the reaction [Streptozocin results in increased expression of PYCARD protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of PYCARD mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of PYCARD protein]
[Streptozocin co-treated with Dextran Sulfate] results in increased expression of PYCARD protein
Streptozocin results in increased expression of PYCARD mRNA; Streptozocin results in increased expression of PYCARD protein		 CTD PMID:23647015 PMID:32202043 PMID:34964214 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Pygl glycogen phosphorylase L multiple interactions
decreases expression		 EXP [Streptozocin co-treated with Niacinamide] affects the activity of PYGL protein; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] affects the activity of PYGL protein]
Streptozocin results in decreased expression of PYGL mRNA		 CTD PMID:19059388 PMID:25905778 NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310 		JBrowse link
G Pygm glycogen phosphorylase, muscle associated multiple interactions
decreases activity		 EXP Plant Extracts inhibits the reaction [Streptozocin results in decreased activity of PYGM protein]; Polysaccharides inhibits the reaction [Streptozocin results in decreased activity of PYGM protein] CTD PMID:26616445 NCBI chr 1:203,690,550...203,705,369
Ensembl chr 1:203,690,533...203,705,368 		JBrowse link
G Pyroxd2 pyridine nucleotide-disulphide oxidoreductase domain 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of PYROXD2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of PYROXD2 protein]		 CTD PMID:19634143 NCBI chr 1:241,523,278...241,549,083
Ensembl chr 1:241,523,377...241,548,761 		JBrowse link
G Pyy peptide YY multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of PYY mRNA CTD PMID:33484791 NCBI chr10:87,061,155...87,062,278
Ensembl chr10:87,061,161...87,061,815 		JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions
increases activity		 ISO
EXP		 Atorvastatin inhibits the reaction [Streptozocin results in increased activity of and results in increased localization of RAC1 protein]; Streptozocin results in increased activity of and results in increased localization of RAC1 protein
Streptozocin results in increased activity of RAC1 protein
Atorvastatin inhibits the reaction [Streptozocin results in increased activity of RAC1 protein]		 CTD PMID:17279352 PMID:17589825 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Rac2 Rac family small GTPase 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of RAC2 mRNA CTD PMID:25905778 NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions
decreases expression
increases expression		 EXP manumycin inhibits the reaction [Streptozocin results in increased expression of RAF1 protein]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of RAF1 protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased expression of RAF1 protein] CTD PMID:18569938 PMID:23562514 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 affects localization EXP Streptozocin affects the localization of RASGRF1 protein CTD PMID:19002579 NCBI chr 8:90,445,154...90,574,274
Ensembl chr 8:90,445,154...90,574,269 		JBrowse link
G Rasgrp2 RAS guanyl releasing protein 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of RASGRP2 mRNA CTD PMID:25905778 NCBI chr 1:203,705,777...203,722,993
Ensembl chr 1:203,707,481...203,722,993 		JBrowse link
G Rbm39 RNA binding motif protein 39 decreases expression EXP Streptozocin results in decreased expression of RBM39 mRNA CTD PMID:25905778 NCBI chr 3:144,662,998...144,696,222
Ensembl chr 3:144,663,001...144,696,213 		JBrowse link
G Rbp4 retinol binding protein 4 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein; Berberine inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein]; cinnamaldehyde inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein] CTD PMID:19080170 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399 		JBrowse link
G Rbpjl recombination signal binding protein for immunoglobulin kappa J region-like multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of RBPJL mRNA CTD PMID:33484791 NCBI chr 3:153,134,044...153,147,421
Ensembl chr 3:153,134,140...153,146,513 		JBrowse link
G Rdh16 retinol dehydrogenase 16 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of RDH2 mRNA CTD PMID:25905778 NCBI chr 7:63,616,711...63,625,053
Ensembl chr 7:63,597,536...63,624,124 		JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions EXP Streptozocin affects the localization of and results in increased activity of REL protein CTD PMID:19002579 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases localization
increases phosphorylation
increases activity
affects localization
increases expression		 ISO
EXP		 TNF protein inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]
Streptozocin results in increased localization of RELA protein
Streptozocin results in increased phosphorylation of RELA protein
Streptozocin results in increased activity of RELA protein
Streptozocin affects the localization of RELA protein
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in increased expression of and results in decreased phosphorylation of RELA protein]]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of RELA protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of RELA protein; [Niacinamide co-treated with Streptozocin] results in increased expression of RELA protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein; [Streptozocin co-treated with Niacinamide] results in increased activity of RELA protein; [Streptozocin co-treated with Niacinamide] results in increased expression of RELA protein; [Telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of RELA protein]; AC3056 inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Angiotensin Receptor Antagonists inhibits the reaction [Streptozocin results in increased expression of RELA protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of RELA protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of RELA protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of RELA protein]; benazepril inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Calcitriol inhibits the reaction [Streptozocin results in increased expression of and results in decreased phosphorylation of RELA protein]; chromium mesoporphyrin inhibits the reaction [Hemin inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]]; crocin inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Curcumin inhibits the reaction [Streptozocin affects the localization of RELA protein]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of and affects the localization of RELA protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of RELA protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of RELA protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Hemin inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of RELA protein modified form]; mangiferin inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; nifuroxazide inhibits the reaction [Streptozocin results in increased localization of RELA protein]; Phycocyanin inhibits the reaction [Streptozocin results in increased expression of RELA protein]; pinitol inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of RELA protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased activity of RELA protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of RELA protein]; Rivastigmine inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Streptozocin affects the localization of and results in decreased activity of RELA protein; Streptozocin promotes the reaction [IGF2R protein modified form results in increased expression of RELA protein modified form]; Streptozocin results in increased expression of and affects the localization of RELA protein; Streptozocin results in increased expression of and results in decreased phosphorylation of RELA protein; Streptozocin results in increased expression of and results in increased phosphorylation of RELA protein; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of RELA protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in increased expression of RELA protein]]; Zinc inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]
Streptozocin results in increased expression of RELA mRNA; Streptozocin results in increased expression of RELA protein; Streptozocin results in increased expression of RELA protein modified form
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased phosphorylation of RELA protein]; 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of RELA protein modified form]; [Streptozocin co-treated with Dextran Sulfate] results in increased phosphorylation of RELA protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of RELA mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein; [Streptozocin co-treated with Niacinamide] results in increased phosphorylation of RELA protein; AICA ribonucleotide inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of RELA protein]; asiatic acid inhibits the reaction [Streptozocin results in increased expression of RELA protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA mRNA]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; Carnosine inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Carnosine promotes the reaction [asiatic acid inhibits the reaction [Streptozocin results in increased expression of RELA protein]]; EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased activity of RELA protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased phosphorylation of RELA protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of and affects the localization of RELA protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin promotes the reaction [RELA protein binds to MMP9 promoter]]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of RELA protein]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [RELA protein binds to PARP1 protein]]; Streptozocin promotes the reaction [RELA protein binds to MMP9 promoter]; Streptozocin promotes the reaction [RELA protein binds to PARP1 protein]; Streptozocin results in increased expression of and affects the localization of RELA protein; Streptozocin results in increased phosphorylation of and results in increased activity of RELA protein; Tadalafil inhibits the reaction [Streptozocin results in increased expression of RELA protein modified form]		 CTD PMID:17900838 PMID:19002579 PMID:19040617 PMID:19123331 PMID:19133311 More... NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Retn resistin multiple interactions
increases expression		 EXP resveratrol inhibits the reaction [Streptozocin results in increased expression of RETN protein] CTD PMID:26071184 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620 		JBrowse link
G Rhbdf2 rhomboid 5 homolog 2 multiple interactions
increases expression		 EXP Diosgenin inhibits the reaction [Streptozocin results in increased expression of RHBDF2 mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of RHBDF2 protein]
Streptozocin results in increased expression of RHBDF2 mRNA; Streptozocin results in increased expression of RHBDF2 protein		 CTD PMID:35305976 NCBI chr10:101,833,157...101,860,283
Ensembl chr10:101,833,157...101,860,283 		JBrowse link
G Rhoa ras homolog family member A multiple interactions
increases expression
increases activity		 EXP [Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased expression of RHOA protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased activity of RHOA protein]; Ramipril inhibits the reaction [Streptozocin results in increased expression of RHOA protein] CTD PMID:17589825 PMID:23376009 PMID:31062909 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Rnf2 ring finger protein 2 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of RNF2 mRNA CTD PMID:28946194 NCBI chr13:63,553,964...63,584,047
Ensembl chr13:63,554,862...63,583,099 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 multiple interactions
increases activity
increases expression		 EXP fasudil inhibits the reaction [Streptozocin results in increased activity of ROCK1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of ROCK1 mRNA]
Streptozocin results in increased expression of ROCK1 mRNA; Streptozocin results in increased expression of ROCK1 protein		 CTD PMID:22429817 PMID:23376009 PMID:31062909 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ROCK2 protein
[Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased expression of ROCK2 protein]; Ramipril inhibits the reaction [Streptozocin results in increased expression of ROCK2 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of ROCK2 protein]		 CTD PMID:31062909 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
G Rpl18a ribosomal protein L18A increases expression
multiple interactions		 EXP Streptozocin results in increased expression of RPL18A mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of RPL18A mRNA]		 CTD PMID:16684804 NCBI chr16:18,542,555...18,544,578
Ensembl chr16:18,542,566...18,545,546 		JBrowse link
G Rprm reprimo, TP53 dependent G2 arrest mediator homolog multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of RPRM mRNA CTD PMID:25905778 NCBI chr 3:38,539,581...38,540,998
Ensembl chr 3:38,539,581...38,540,998 		JBrowse link
G Rps3 ribosomal protein S3 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of RPS3 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of RPS3 mRNA]		 CTD PMID:16684804 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression
multiple interactions		 EXP Streptozocin results in increased expression of RRAD mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of RRAD mRNA]		 CTD PMID:16684804 NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417 		JBrowse link
G RT1-DMa RT1 class II, locus DMa multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of RT1-DMA mRNA CTD PMID:25905778 NCBI chr20:4,707,028...4,710,432
Ensembl chr20:4,707,028...4,710,432 		JBrowse link
G RT1-DMb RT1 class II, locus DMb multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of RT1-DMB mRNA CTD PMID:25905778 NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340 		JBrowse link
G Runx2 RUNX family transcription factor 2 decreases expression EXP Streptozocin results in decreased expression of RUNX2 mRNA CTD PMID:25617479 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Rwdd2a RWD domain containing 2A multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of RWDD2A mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of RWDD2A mRNA] CTD PMID:33484791 NCBI chr 8:87,536,153...87,539,301
Ensembl chr 8:87,536,176...87,539,300 		JBrowse link
G Ryr2 ryanodine receptor 2 decreases activity
multiple interactions		 EXP
ISO		 Streptozocin results in decreased activity of RYR2 protein
[octylphenol co-treated with Streptozocin] results in increased expression of RYR2 mRNA		 CTD PMID:16685413 PMID:29935216 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142 		JBrowse link
G S100a6 S100 calcium binding protein A6 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of S100A6 mRNA CTD PMID:25905778 NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180 		JBrowse link
G S100a8 S100 calcium binding protein A8 multiple interactions
increases expression		 ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of S100A8 mRNA; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Streptozocin results in increased expression of S100A8 mRNA] CTD PMID:19833897 PMID:29127188 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of S100A9 mRNA CTD PMID:25905778 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G S100b S100 calcium binding protein B multiple interactions
decreases expression
increases expression		 EXP pimagedine inhibits the reaction [Streptozocin results in decreased expression of S100B protein]; pimagedine inhibits the reaction [Streptozocin results in increased expression of S100B protein] CTD PMID:19494442 PMID:20953641 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G S1pr2 sphingosine-1-phosphate receptor 2 increases expression EXP Streptozocin results in increased expression of S1PR2 mRNA CTD PMID:22406263 NCBI chr 8:19,503,276...19,514,169
Ensembl chr 8:19,502,627...19,523,574 		JBrowse link
G S1pr4 sphingosine-1-phosphate receptor 4 increases expression EXP Streptozocin results in increased expression of S1PR4 mRNA CTD PMID:22406263 NCBI chr 7:8,207,767...8,210,043
Ensembl chr 7:8,208,098...8,211,893 		JBrowse link
G S1pr5 sphingosine-1-phosphate receptor 5 increases expression EXP Streptozocin results in increased expression of S1PR5 mRNA CTD PMID:22406263 NCBI chr 8:19,786,676...19,791,862
Ensembl chr 8:19,786,663...19,791,795 		JBrowse link
G Scara5 scavenger receptor class A, member 5 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of SCARA5 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SCARA5 mRNA] CTD PMID:33484791 NCBI chr15:39,880,017...39,985,007
Ensembl chr15:39,880,035...39,983,373 		JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions
increases expression 		ISO
EXP		 [Dietary Fats co-treated with Streptozocin] results in increased expression of SCD1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SCD1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of SCD1 mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SCD1 mRNA]
streptozocin increases expression of Scd protein in liver
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of SCD1 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of SCD1 mRNA; [Dietary Fats affects the susceptibility to Streptozocin] which results in decreased expression of SCD1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of SCD1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SCD1 mRNA		 CTD
RGD		 PMID:29127188 PMID:29988851 PMID:34896238 PMID:35786680 PMID:32535406 RGD:401850547 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Sdha succinate dehydrogenase complex flavoprotein subunit A increases expression
multiple interactions		 EXP Streptozocin results in increased expression of SDHA protein
Trientine inhibits the reaction [Streptozocin results in increased expression of SDHA protein]		 CTD PMID:19634143 PMID:21136691 NCBI chr 1:28,935,965...28,960,936
Ensembl chr 1:28,940,164...28,961,535 		JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B multiple interactions
increases expression		 EXP
ISO		 Trientine inhibits the reaction [Streptozocin results in increased expression of SDHB protein]
[Streptozocin co-treated with Dietary Fats] results in decreased expression of SDHB mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SDHB mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SDHB mRNA]		 CTD PMID:19634143 PMID:37337224 NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293 		JBrowse link
G Sds serine dehydratase multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of SDS mRNA CTD PMID:25905778 NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203 		JBrowse link
G Selenop selenoprotein P multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of SELENOP mRNA; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SELENOP mRNA] CTD PMID:26522834 NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852 		JBrowse link
G Selp selectin P multiple interactions EXP [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of SELP protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of SELP protein]] CTD PMID:36547818 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845 		JBrowse link
G Serpina4 serpin family A member 4 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of SERPINA4-PS1 mRNA CTD PMID:33484791 NCBI chr 6:122,999,970...123,009,083
Ensembl chr 6:122,999,900...123,009,082 		JBrowse link
G Serpina6 serpin family A member 6 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of SERPINA6 mRNA CTD PMID:25905778 NCBI chr 6:122,780,040...122,790,274
Ensembl chr 6:122,780,043...122,790,349 		JBrowse link
G Serpina7 serpin family A member 7 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of SERPINA7 mRNA CTD PMID:25905778 NCBI chr  X:102,663,242...102,722,319
Ensembl chr  X:102,663,405...102,669,040 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions
increases expression		 ISO
EXP		 SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SERPINE1]; Streptozocin promotes the reaction [MAP3K5 protein results in increased expression of SERPINE1 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of SERPINE1 protein]
Streptozocin results in increased expression of SERPINE1; Streptozocin results in increased expression of SERPINE1 mRNA; Streptozocin results in increased expression of SERPINE1 protein
benazepril inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]; Trientine inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]; Zinc inhibits the reaction [Streptozocin results in increased expression of SERPINE1 protein]		 CTD PMID:15322501 PMID:16731828 PMID:16973718 PMID:19369054 PMID:21778425 More... NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Serpine2 serpin family E member 2 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of SERPINE2 protein; Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SERPINE2 protein]; sarpogrelate inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SERPINE2 protein] CTD PMID:27097221 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Serpinh1 serpin family H member 1 increases expression EXP Streptozocin results in increased expression of SERPINH1 protein CTD PMID:12197670 NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801 		JBrowse link
G Setd7 SET domain containing 7, histone lysine methyltransferase multiple interactions EXP Streptozocin promotes the reaction [SETD7 protein binds to CDKN1A promoter] CTD PMID:27652271 NCBI chr 2:135,562,683...135,605,468
Ensembl chr 2:135,562,683...135,605,468 		JBrowse link
G Sfxn1 sideroflexin 1 multiple interactions
increases expression		 EXP Trientine inhibits the reaction [Streptozocin results in increased expression of SFXN1 protein] CTD PMID:19634143 NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression ISO Streptozocin results in increased expression of SGK1 mRNA; Streptozocin results in increased expression of SGK1 protein CTD PMID:16116964 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283 		JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 increases expression ISO Streptozocin results in increased expression of SGK2 mRNA CTD PMID:16116964 NCBI chr 3:151,644,102...151,669,480
Ensembl chr 3:151,644,102...151,669,480 		JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase family, member 3 increases expression ISO Streptozocin results in increased expression of SGK3 mRNA CTD PMID:16116964 NCBI chr 5:9,345,761...9,472,243
Ensembl chr 5:9,346,040...9,415,476 		JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of SH3GLB1 mRNA CTD PMID:25905778 NCBI chr 2:233,750,838...233,784,817
Ensembl chr 2:233,750,838...233,784,784 		JBrowse link
G Shc1 SHC adaptor protein 1 multiple interactions
increases expression		 ISO SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SHC1 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SHC1 protein]
Streptozocin results in increased expression of SHC1 mRNA; Streptozocin results in increased expression of SHC1 protein		 CTD PMID:21778425 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536 		JBrowse link
G Sim2 SIM bHLH transcription factor 2 increases expression EXP Streptozocin results in increased expression of SIM2 protein CTD PMID:23333261 NCBI chr11:33,414,218...33,453,663
Ensembl chr11:33,414,218...33,453,663 		JBrowse link
G Sirt1 sirtuin 1 decreases activity
decreases expression
multiple interactions		 ISO
EXP		 Streptozocin results in decreased activity of SIRT1 protein
Streptozocin results in decreased expression of SIRT1 protein
Streptozocin results in decreased expression of SIRT1 mRNA; Streptozocin results in decreased expression of SIRT1 protein
[Streptozocin co-treated with bisphenol A] results in decreased expression of SIRT1 protein; [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in increased expression of SIRT1 protein; [Streptozocin co-treated with Resveratrol] results in increased expression of SIRT1 protein; Organoselenium Compounds inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of SIRT1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of SIRT1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SIRT1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SIRT1 protein; AICA ribonucleotide inhibits the reaction [Streptozocin results in decreased activity of SIRT1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SIRT1 protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SIRT1 mRNA]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased activity of SIRT1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to PARP1 protein]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [PARP1 protein binds to MMP9 promoter]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [RELA protein binds to PARP1 protein]]; SIRT1 protein inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; SIRT1 protein inhibits the reaction [Streptozocin results in decreased expression of SOD2]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN1A]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SERPINE1]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SHC1 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SHC1 protein]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SIRT1 mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SIRT1 protein]		 CTD PMID:21778425 PMID:22058332 PMID:22733486 PMID:22744176 PMID:23792339 More... NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slc10a2 solute carrier family 10 member 2 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of SLC10A2 mRNA CTD PMID:29382564 NCBI chr16:84,386,528...84,409,475
Ensembl chr16:84,374,862...84,409,475 		JBrowse link
G Slc13a5 solute carrier family 13 member 5 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of SLC13A5 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SLC13A5 mRNA] CTD PMID:33484791 NCBI chr10:56,866,249...56,891,189
Ensembl chr10:56,866,249...56,890,945 		JBrowse link
G Slc15a3 solute carrier family 15 member 3 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of SLC15A3 mRNA CTD PMID:25905778 NCBI chr 1:207,492,365...207,507,158
Ensembl chr 1:207,492,365...207,507,157 		JBrowse link
G Slc1a3 solute carrier family 1 member 3 multiple interactions
decreases expression		 EXP Curcumin inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 mRNA]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 mRNA]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 protein]
Streptozocin results in decreased expression of SLC1A3 mRNA; Streptozocin results in decreased expression of SLC1A3 protein		 CTD PMID:23267840 PMID:26677078 NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605 		JBrowse link
G Slc20a2 solute carrier family 20 member 2 multiple interactions
increases expression		 ISO INS1 protein inhibits the reaction [Streptozocin results in increased expression of SLC20A2 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of SLC20A2 protein]
Streptozocin results in increased expression of SLC20A2 mRNA; Streptozocin results in increased expression of SLC20A2 protein		 CTD PMID:29216956 NCBI chr16:69,460,850...69,551,418
Ensembl chr16:69,460,462...69,521,711 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 decreases expression EXP Streptozocin results in decreased expression of SLC22A1 protein CTD PMID:19605544 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases expression EXP Streptozocin results in decreased expression of SLC22A2 protein CTD PMID:19605544 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions
decreases expression		 EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of SLC22A6 protein] CTD PMID:19634143 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173 		JBrowse link
G Slc25a1 solute carrier family 25 member 1 multiple interactions
decreases expression		 EXP cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A1 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A1 protein]] CTD PMID:16595661 NCBI chr11:83,055,764...83,058,781
Ensembl chr11:83,055,748...83,058,781 		JBrowse link
G Slc25a10 solute carrier family 25 member 10 increases expression
decreases expression
multiple interactions		 EXP Streptozocin results in increased expression of SLC25A10 protein
Streptozocin results in decreased expression of SLC25A10 protein
cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A10 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A10 protein]]; Trientine inhibits the reaction [Streptozocin results in increased expression of SLC25A10 protein]		 CTD PMID:16595661 PMID:19634143 NCBI chr10:105,765,598...105,775,159
Ensembl chr10:105,765,372...105,773,556 		JBrowse link
G Slc25a19 solute carrier family 25 member 19 multiple interactions
decreases expression		 ISO
EXP		 HMOX1 protein inhibits the reaction [Streptozocin results in decreased expression of SLC25A19 protein]
cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A19 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A19 protein]]		 CTD PMID:16595661 NCBI chr10:100,853,554...100,867,517
Ensembl chr10:100,847,168...100,867,447 		JBrowse link
G Slc25a20 solute carrier family 25 member 20 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of SLC25A20 protein
cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A20 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A20 protein]]		 CTD PMID:16595661 NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512 		JBrowse link
G Slc25a26 solute carrier family 25 member 26 affects expression ISO Streptozocin affects the expression of SLC25A26 mRNA CTD PMID:18583417 NCBI chr 4:127,036,704...127,131,026
Ensembl chr 4:127,036,742...127,131,020 		JBrowse link
G Slc25a3 solute carrier family 25 member 3 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of SLC25A3 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of SLC25A3 protein]		 CTD PMID:19634143 NCBI chr 7:25,611,937...25,619,401
Ensembl chr 7:25,586,725...25,667,727 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 multiple interactions ISO SLC25A4 protein inhibits the reaction [Streptozocin results in increased expression of NPPA mRNA] CTD PMID:18945756 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733 		JBrowse link
G Slc25a47 solute carrier family 25, member 47 affects expression ISO Streptozocin affects the expression of SLC25A47 mRNA CTD PMID:18583417 NCBI chr 6:127,767,365...127,773,000
Ensembl chr 6:127,767,305...127,773,005 		JBrowse link
G Slc25a5 solute carrier family 25 member 5 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of SLC25A5 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of SLC25A5 protein]		 CTD PMID:19634143 NCBI chr  X:116,031,896...116,034,963
Ensembl chr  X:116,031,803...116,034,967 		JBrowse link
G Slc27a1 solute carrier family 27 member 1 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of SLC27A1 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of SLC27A1 mRNA]		 CTD PMID:16684804 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063 		JBrowse link
G Slc27a5 solute carrier family 27 member 5 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC27A5 mRNA CTD PMID:29382564 NCBI chr 1:73,616,556...73,627,149
Ensembl chr 1:73,616,564...73,627,172 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions
increases expression		 EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A1 protein; bicalutamide promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A1 protein]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of SLC2A1 mRNA] CTD PMID:16409969 PMID:35151640 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 increases response to substance
increases expression
decreases expression
multiple interactions		 EXP
ISO		 SLC2A2 protein results in increased susceptibility to Streptozocin
Streptozocin results in increased expression of SLC2A2 protein
Streptozocin results in decreased expression of SLC2A2 protein
[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A2 mRNA; [Streptozocin co-treated with Cadmium] results in decreased expression of SLC2A2 protein; allyl isothiocyanate inhibits the reaction [Streptozocin promotes the reaction [Dietary Fats results in decreased expression of SLC2A2 protein]]; allyl methyl sulfide inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of SLC2A2 protein]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]; repaglinide analog affects the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A2 mRNA]; repaglinide inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A2 mRNA]; Streptozocin promotes the reaction [Dietary Fats results in decreased expression of SLC2A2 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of SLC2A2 protein]
5-thio-D-glucose inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 mRNA]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A2 protein; Dibutyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A2 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A2 mRNA]; L 783281 inhibits the reaction [Dibutyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A2 protein]]		 CTD PMID:11151762 PMID:12137914 PMID:24923654 PMID:25541178 PMID:27417257 More... NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 affects expression
multiple interactions
decreases expression
affects localization		 EXP
ISO		 Streptozocin affects the expression of SLC2A4 protein
[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein; [Streptozocin co-treated with bisphenol A] results in decreased expression of SLC2A4 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 protein]; Metformin inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; Streptozocin inhibits the reaction [Ethinyl Estradiol results in increased expression of SLC2A4 mRNA]; Streptozocin inhibits the reaction [octylphenol results in increased expression of SLC2A4 mRNA]
Streptozocin results in decreased expression of SLC2A4 mRNA
[Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of SLC2A4 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of SLC2A4 protein; Berberine inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; bis(maltolato)oxovanadium(IV) inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; chebulagic acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 protein]; chromium mesoporphyrin inhibits the reaction [Hemin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]]; cinnamaldehyde inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; cinnamaldehyde inhibits the reaction [Streptozocin affects the localization of SLC2A4 protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of SLC2A4 protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 mRNA]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Hemin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; INS protein inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; mangiferin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; mangiferin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; naloxonazine inhibits the reaction [Valsartan inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]]; naloxonazine inhibits the reaction [Valsartan inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]]; Naloxone inhibits the reaction [Tramadol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]]; naringenin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; naringenin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 mRNA]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 mRNA]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; Plant Extracts inhibits the reaction [Streptozocin affects the localization of SLC2A4 protein]; plumbagin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; plumbagin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Polysaccharides inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Polysaccharides inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of SLC2A4 protein]; Resveratrol inhibits the reaction [Streptozocin inhibits the reaction [CAV3 protein binds to SLC2A4 protein]]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Streptozocin inhibits the reaction [CAV3 protein binds to SLC2A4 protein]; Tramadol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Tramadol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]
Streptozocin results in decreased expression of SLC2A4 mRNA; Streptozocin results in decreased expression of SLC2A4 protein		 CTD PMID:11723065 PMID:12083368 PMID:12658023 PMID:17068109 PMID:17199717 More... NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
G Slc31a1 solute carrier family 31 member 1 decreases expression EXP Streptozocin results in decreased expression of SLC31A1 mRNA; Streptozocin results in decreased expression of SLC31A1 protein CTD PMID:24927960 NCBI chr 5:75,814,744...75,844,241
Ensembl chr 5:75,814,743...75,844,228 		JBrowse link
G Slc31a2 solute carrier family 31 member 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of SLC31A2 mRNA; Streptozocin results in increased expression of SLC31A2 protein
Trientine promotes the reaction [Streptozocin results in increased expression of SLC31A2 mRNA]; Trientine promotes the reaction [Streptozocin results in increased expression of SLC31A2 protein]		 CTD PMID:24927960 NCBI chr 5:75,738,008...75,748,542
Ensembl chr 5:75,738,024...75,748,542 		JBrowse link
G Slc35b2 solute carrier family 35 member B2 multiple interactions
decreases expression		 EXP cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC35B2 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC35B2 protein]] CTD PMID:16595661 NCBI chr 9:15,438,594...15,442,227
Ensembl chr 9:15,438,594...15,442,234 		JBrowse link
G Slc3a1 solute carrier family 3 member 1 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of SLC3A1 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of SLC3A1 protein]		 CTD PMID:19634143 NCBI chr 6:9,608,169...9,641,881
Ensembl chr 6:9,608,178...9,641,907 		JBrowse link
G Slc51a solute carrier family 51 member A multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of SLC51A mRNA CTD PMID:29382564 NCBI chr11:68,299,086...68,313,485
Ensembl chr11:68,299,086...68,313,485 		JBrowse link
G Slc51b SLC51 subunit beta multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of SLC51B mRNA CTD PMID:29382564 NCBI chr 8:65,931,891...65,939,953
Ensembl chr 8:65,931,890...65,940,145 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased activity of SLC6A4 protein; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of SLC6A4 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased activity of SLC6A4 protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of SLC6A4 mRNA] CTD PMID:32303808 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Slc6a6 solute carrier family 6 member 6 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of SLC6A6 mRNA CTD PMID:25905778 NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875 		JBrowse link
G Slc7a7 solute carrier family 7 member 7 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of SLC7A7 mRNA CTD PMID:25905778 NCBI chr15:27,822,088...27,873,121
Ensembl chr15:27,822,091...27,865,648 		JBrowse link
G Smad1 SMAD family member 1 increases expression EXP Streptozocin results in increased expression of SMAD1 CTD PMID:25617480 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651 		JBrowse link
G Smad2 SMAD family member 2 increases phosphorylation
multiple interactions		 EXP
ISO		 Streptozocin results in increased phosphorylation of SMAD2 protein
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased phosphorylation of SMAD2 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased phosphorylation of SMAD2 protein
[Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in decreased phosphorylation of SMAD2 protein; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of SMAD2 protein]		 CTD PMID:21300041 PMID:31062909 PMID:38282657 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad3 SMAD family member 3 multiple interactions
increases phosphorylation		 EXP
ISO		 resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of SMAD3 protein]
[fatostatin co-treated with Streptozocin] results in increased phosphorylation of SMAD3 protein; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased phosphorylation of SMAD3 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased phosphorylation of SMAD3 protein		 CTD PMID:21300041 PMID:29420703 PMID:38282657 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smad4 SMAD family member 4 multiple interactions
decreases expression
increases expression		 EXP
ISO		 Trientine inhibits the reaction [Streptozocin results in increased expression of SMAD4 mRNA]
Streptozocin results in decreased expression of SMAD4 mRNA
SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of SMAD4 mRNA]
Streptozocin results in increased expression of SMAD4 mRNA; Streptozocin results in increased expression of SMAD4 protein		 CTD PMID:16973718 PMID:18246672 PMID:27629361 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Smad6 SMAD family member 6 increases expression EXP Streptozocin results in increased expression of SMAD6 protein CTD PMID:17437042 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763 		JBrowse link
G Smad7 SMAD family member 7 affects expression EXP Streptozocin affects the expression of SMAD7 mRNA; Streptozocin affects the expression of SMAD7 protein CTD PMID:17437042 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 decreases response to substance ISO SMPD1 gene mutant form results in decreased susceptibility to Streptozocin CTD PMID:32481596 NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794 		JBrowse link
G Snap23 synaptosome associated protein 23 multiple interactions EXP [Streptozocin co-treated with Niacinamide] results in decreased expression of SNAP23 mRNA; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of SNAP23 mRNA] CTD PMID:25999625 NCBI chr 3:107,514,088...107,546,177
Ensembl chr 3:107,514,131...107,544,320 		JBrowse link
G Sncb synuclein, beta multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of SNCB mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SNCB mRNA] CTD PMID:33484791 NCBI chr17:9,846,802...9,855,013
Ensembl chr17:9,846,802...9,855,012 		JBrowse link
G Sncg synuclein, gamma increases expression
multiple interactions		 EXP Streptozocin results in increased expression of SNCG mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of SNCG mRNA]		 CTD PMID:16684804 NCBI chr16:9,700,513...9,705,751
Ensembl chr16:9,700,514...9,705,368 		JBrowse link
G Snord15a small nucleolar RNA, C/D box 15A increases expression ISO Streptozocin results in increased expression of SNORD15A mRNA CTD PMID:27629361 NCBI chr 1:153,782,788...153,782,935
Ensembl chr 1:153,782,788...153,782,935 		JBrowse link
G Snord49a small nucleolar RNA, C/D box 49A increases expression ISO Streptozocin results in increased expression of SNORD49A mRNA CTD PMID:27629361 NCBI chr10:47,297,488...47,297,559
Ensembl chr10:47,297,488...47,297,559 		JBrowse link
G Snx12 sorting nexin 12 multiple interactions
decreases expression		 EXP [Antagomirs results in decreased expression of MIR140 mRNA] inhibits the reaction [Streptozocin results in decreased expression of SNX12 protein]; Isoflurane promotes the reaction [Streptozocin results in decreased expression of SNX12 protein] CTD PMID:32062618 NCBI chr  X:66,226,995...66,356,945
Ensembl chr  X:66,227,053...66,356,950 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of SOCS3 protein
rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of SOCS3 protein]		 CTD PMID:21599458 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787 		JBrowse link
G Sod1 superoxide dismutase 1 increases expression
decreases expression
multiple interactions
affects expression
decreases activity		 ISO
EXP		 Streptozocin results in increased expression of SOD1 mRNA
Streptozocin results in decreased expression of SOD1 protein
SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of CITED2 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of ETS1 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MEF2C mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MIR27A mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MIR322 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of SMAD4 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of ZEB2 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR142 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR144 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR448 mRNA]
Streptozocin results in decreased expression of SOD1 mRNA; Streptozocin results in decreased expression of SOD1 protein
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of SOD1 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SOD1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of SOD1 protein; Berberine inhibits the reaction [Streptozocin affects the expression of SOD1 mRNA]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SOD1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of SOD1 protein]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of SOD1 protein]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 mRNA]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]
Streptozocin results in increased expression of SOD1 protein
Streptozocin results in decreased activity of SOD1 protein
[Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; [Resveratrol co-treated with Streptozocin] results in decreased expression of and results in decreased activity of SOD1 protein; [Resveratrol co-treated with Streptozocin] results in decreased expression of SOD1 mRNA; [Streptozocin co-treated with bisphenol A] results in decreased expression of SOD1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of SOD1 protein; allyl methyl sulfide inhibits the reaction [Streptozocin results in decreased activity of SOD1 protein]; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of SOD1 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; Dronabinol promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of SOD1 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; nifuroxazide inhibits the reaction [Streptozocin results in decreased activity of SOD1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of SOD1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of SOD1 protein]; Streptozocin results in decreased expression of and results in decreased activity of SOD1 protein; Trientine inhibits the reaction [Streptozocin results in decreased expression of and results in decreased activity of SOD1 protein]; Trientine inhibits the reaction [Streptozocin results in decreased expression of SOD1 protein]		 CTD PMID:15298345 PMID:18583417 PMID:19634143 PMID:20053369 PMID:20654064 More... NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression
decreases expression
decreases activity
affects expression
multiple interactions
decreases response to substance		 ISO
EXP		 Streptozocin results in increased expression of SOD2 mRNA
Streptozocin results in decreased expression of SOD2 mRNA; Streptozocin results in decreased expression of SOD2 protein
Streptozocin results in decreased activity of SOD2 protein
Streptozocin results in decreased expression of SOD2; Streptozocin results in decreased expression of SOD2 protein
Streptozocin affects the expression of SOD2 mRNA
[Dietary Fats co-treated with Streptozocin] results in decreased expression of SOD2 mRNA; [Streptozocin co-treated with INS1 protein co-treated with Glutathione] affects the expression of SOD2 mRNA; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; Berberine inhibits the reaction [Streptozocin affects the expression of SOD2 mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SOD2 mRNA]; Physostigmine inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; SIRT1 protein inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; SIRT1 protein inhibits the reaction [Streptozocin results in decreased expression of SOD2]; SOD2 protein inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein]
SOD2 protein results in decreased susceptibility to Streptozocin
CAT protein promotes the reaction [SOD2 protein results in decreased susceptibility to Streptozocin]; SOD2 protein promotes the reaction [CAT protein results in decreased susceptibility to Streptozocin]
[Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in decreased expression of SOD2 mRNA]; [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SOD2 mRNA; [Streptozocin co-treated with Cholesterol, Dietary] results in decreased expression of SOD2 protein; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of SOD2 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in decreased expression of SOD2 protein]; idebenone inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; INS protein promotes the reaction [Streptozocin results in decreased activity of SOD2 protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of and results in decreased activity of SOD2 protein]; Streptozocin results in decreased expression of and results in decreased activity of SOD2 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; Thioctic Acid inhibits the reaction [Streptozocin results in decreased activity of SOD2 protein]; Trientine inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]		 CTD PMID:14871415 PMID:15298345 PMID:15855331 PMID:18779489 PMID:19634143 More... NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sod3 superoxide dismutase 3 multiple interactions
decreases expression		 EXP
ISO		 cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SOD3 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SOD3 protein]]; Trientine inhibits the reaction [Streptozocin results in decreased expression of SOD3 mRNA]; Trientine inhibits the reaction [Streptozocin results in decreased expression of SOD3 protein]
[Streptozocin results in decreased activity of SOD3 protein] which results in increased chemical synthesis of Peroxynitrous Acid; [Streptozocin results in decreased activity of SOD3 protein] which results in increased chemical synthesis of Superoxides; Copper inhibits the reaction [Streptozocin results in decreased activity of SOD3 protein]; INS protein inhibits the reaction [Streptozocin results in decreased activity of SOD3 protein]; SOD3 gene mutant form promotes the reaction [Streptozocin results in increased chemical synthesis of Superoxides]; Streptozocin results in increased expression of and results in decreased activity of SOD3 protein
Streptozocin results in decreased expression of SOD3 mRNA; Streptozocin results in decreased expression of SOD3 protein		 CTD PMID:15821039 PMID:16973718 PMID:23884884 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
G Sord sorbitol dehydrogenase multiple interactions
increases glycation
increases expression		 EXP Streptozocin results in decreased expression of and results in decreased activity of SORD protein
Streptozocin results in increased glycation of SORD protein
Streptozocin results in increased expression of SORD mRNA		 CTD PMID:8761460 NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133 		JBrowse link
G Sort1 sortilin 1 decreases expression ISO Streptozocin results in decreased expression of SORT1 protein CTD PMID:25805502 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354 		JBrowse link
G Sox11 SRY-box transcription factor 11 decreases expression EXP Streptozocin results in decreased expression of SOX11 mRNA; Streptozocin results in decreased expression of SOX11 protein CTD PMID:32935389 NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354 		JBrowse link
G Spag9 sperm associated antigen 9 decreases expression EXP Streptozocin results in decreased expression of SPAG9 mRNA CTD PMID:25905778 NCBI chr10:78,943,439...79,077,797
Ensembl chr10:78,943,479...79,077,797 		JBrowse link
G Sparc secreted protein acidic and cysteine rich increases expression ISO Streptozocin results in increased expression of SPARC mRNA; Streptozocin results in increased expression of SPARC protein CTD PMID:12660331 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396 		JBrowse link
G Sphk1 sphingosine kinase 1 increases expression ISO
EXP		 Streptozocin results in increased expression of SPHK1
Streptozocin results in increased expression of SPHK1 mRNA; Streptozocin results in increased expression of SPHK1 protein		 CTD PMID:19657322 PMID:21998146 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions
increases expression		 EXP Pioglitazone inhibits the reaction [Streptozocin results in increased expression of SPP1 mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of SPP1 protein]; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of SPP1 mRNA]
Streptozocin results in increased expression of SPP1 mRNA; Streptozocin results in increased expression of SPP1 protein		 CTD PMID:16684804 PMID:16979161 PMID:16980342 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Sprr2a2 small proline-rich protein 2A2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of SPRR2A2 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of SPRR2A2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SPRR2A2 mRNA] CTD PMID:33484791 NCBI chr 2:177,719,576...177,719,845
Ensembl chr 2:177,719,576...177,719,845 		JBrowse link
G Spsb4 splA/ryanodine receptor domain and SOCS box containing 4 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of SPSB4 mRNA CTD PMID:25905778 NCBI chr 8:97,536,519...97,609,757
Ensembl chr 8:97,536,520...97,609,787 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
increases expression		 ISO
EXP		 bafilomycin A1 inhibits the reaction [Resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]]; HU 308 inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]; Streptozocin promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]
[Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of SQSTM1 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of SQSTM1 protein		 CTD PMID:24889822 PMID:30459625 PMID:35786680 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of SRD5A1 mRNA CTD PMID:29127188 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions
increases expression
decreases expression		 EXP
ISO		 [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of SREBF1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of SREBF1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 protein; [Streptozocin co-treated with Cadmium] results in increased expression of SREBF1 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of SREBF1 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of SREBF1 protein]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF1 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of SREBF1 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of SREBF1 protein]
streptozocin increases expression of Srebf1 protein in liver
Streptozocin results in increased expression of SREBF1 mRNA; Streptozocin results in increased expression of SREBF1 protein
[Dietary Fats co-treated with Streptozocin] results in decreased expression of SREBF1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of SREBF1 mRNA]; fatostatin inhibits the reaction [Streptozocin results in increased expression of SREBF1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SREBF1 mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA]
Streptozocin results in decreased expression of SREBF1 protein		 CTD
RGD		 PMID:22031849 PMID:23647015 PMID:25240712 PMID:28822685 PMID:29420703 More... RGD:401850547 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions
increases expression		 EXP
ISO		 [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of SREBF2 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of SREBF2 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of SREBF2 mRNA; [Streptozocin co-treated with Cadmium] results in increased expression of SREBF2 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of SREBF2 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of SREBF2 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF2 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of SREBF2 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of SREBF2 protein]
Streptozocin results in increased expression of SREBF2 mRNA; Streptozocin results in increased expression of SREBF2 protein
Acrylamide inhibits the reaction [Streptozocin results in increased expression of SREBF2 mRNA]; fatostatin inhibits the reaction [Streptozocin results in increased expression of SREBF2 protein]		 CTD PMID:23647015 PMID:25240712 PMID:29420703 PMID:34896238 PMID:35786680 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848 		JBrowse link
G Srxn1 sulfiredoxin 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of SRXN1 mRNA; Omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SRXN1 mRNA]; Omaveloxolone promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SRXN1 mRNA] CTD PMID:32410268 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448 		JBrowse link
G St3gal5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ST3GAL5 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of ST3GAL5 mRNA]		 CTD PMID:16684804 NCBI chr 4:104,134,613...104,192,558
Ensembl chr 4:104,134,613...104,192,558 		JBrowse link
G Stac3 SH3 and cysteine rich domain 3 decreases expression EXP Streptozocin results in decreased expression of STAC3 mRNA CTD PMID:25905778 NCBI chr 7:63,343,078...63,350,590
Ensembl chr 7:63,343,186...63,350,589 		JBrowse link
G Stag3 STAG3 cohesin complex component multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of STAG3 mRNA CTD PMID:33484791 NCBI chr12:17,284,677...17,314,936
Ensembl chr12:17,284,794...17,314,935 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
decreases phosphorylation
increases phosphorylation
increases expression		 EXP 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of STAT3 mRNA]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of STAT3 protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]]; Enalapril inhibits the reaction [Streptozocin results in increased expression of STAT3 mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of STAT3 protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]; Propofol promotes the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]; Simvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]
Streptozocin results in increased expression of STAT3 mRNA; Streptozocin results in increased expression of STAT3 protein		 CTD PMID:19958114 PMID:20821229 PMID:21599458 PMID:21912612 PMID:24810525 More... NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 multiple interactions EXP STUB1 inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of GSK3B protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of IL1B protein]; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of RELA protein]; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of TNFA protein] CTD PMID:35442559 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046 		JBrowse link
G Stx4 syntaxin 4 multiple interactions EXP [Streptozocin co-treated with Niacinamide] results in decreased expression of STX4 mRNA; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of STX4 mRNA] CTD PMID:25999625 NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979 		JBrowse link
G Sucla2 succinate-CoA ligase ADP-forming subunit beta affects expression ISO Streptozocin affects the expression of SUCLA2 mRNA CTD PMID:18583417 NCBI chr15:48,752,356...48,805,495
Ensembl chr15:48,752,312...48,805,138 		JBrowse link
G Sult1c2a sulfotransferase family 1C member 2A multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of SULT1C2 mRNA CTD PMID:25905778 NCBI chr 9:6,873,697...6,904,736
Ensembl chr 9:6,874,249...6,904,734 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of SULT2A1 mRNA CTD PMID:29382564 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
G Syp synaptophysin increases expression
decreases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of SYP mRNA
Streptozocin results in decreased expression of SYP mRNA; Streptozocin results in decreased expression of SYP protein
fasudil inhibits the reaction [Streptozocin results in decreased expression of SYP mRNA]; fasudil inhibits the reaction [Streptozocin results in decreased expression of SYP protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of SYP protein]
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of SYP protein]; Physostigmine inhibits the reaction [Streptozocin results in decreased expression of SYP protein]; telmisartan inhibits the reaction [Streptozocin results in decreased expression of SYP protein]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of SYP protein]		 CTD PMID:18487452 PMID:22062134 PMID:28499986 PMID:38049026 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745 		JBrowse link
G Syvn1 synoviolin 1 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of SYVN1 protein
4-phenylbutyric acid inhibits the reaction [Streptozocin results in decreased expression of SYVN1 protein]		 CTD PMID:30980806 NCBI chr 1:203,339,235...203,346,137
Ensembl chr 1:203,339,619...203,346,152 		JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions
decreases secretion
increases expression
decreases expression		 EXP Botulinum Toxins, Type A inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein]; Butylated Hydroxytoluene inhibits the reaction [Streptozocin results in increased expression of TAC1 mRNA]; capsazepine inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein]; imirestat inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein]; RN 1734 inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein]; sorbinil inhibits the reaction [Streptozocin results in increased expression of TAC1 mRNA]; Streptozocin promotes the reaction [KNG1 protein modified form results in increased secretion of TAC1 protein modified form]; U 0126 inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein]
Streptozocin results in decreased secretion of TAC1 protein modified form		 CTD PMID:1374869 PMID:9748608 PMID:20832942 PMID:30583000 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178 		JBrowse link
G Tbc1d4 TBC1 domain family, member 4 multiple interactions ISO [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased phosphorylation of TBC1D4 protein; Metformin inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of TBC1D4 protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of TBC1D4 protein] CTD PMID:31743741 NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265 		JBrowse link
G Tedc1 tubulin epsilon and delta complex 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of TEDC1 mRNA CTD PMID:33484791 NCBI chr 6:132,234,764...132,245,164
Ensembl chr 6:132,236,925...132,244,928 		JBrowse link
G Tek TEK receptor tyrosine kinase multiple interactions
decreases expression
increases expression		 EXP baicalin inhibits the reaction [Streptozocin results in decreased expression of TEK mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of TEK mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of TEK mRNA]
Streptozocin results in increased expression of TEK mRNA; Streptozocin results in increased expression of TEK protein		 CTD PMID:15643138 PMID:19958114 PMID:20821229 PMID:34414639 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804 		JBrowse link
G Tfam transcription factor A, mitochondrial multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of TFAM mRNA; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TFAM mRNA] CTD PMID:37337224 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292 		JBrowse link
G Tfap2a transcription factor AP-2 alpha multiple interactions EXP
ISO		 MFN2 protein mutant form inhibits the reaction [Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter]]; Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter]
[Streptozocin co-treated with Raloxifene Hydrochloride] results in increased expression of TFAP2A protein		 CTD PMID:23471663 PMID:27997345 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507 		JBrowse link
G Tfrc transferrin receptor multiple interactions
increases expression		 EXP iron pentacarbonyl inhibits the reaction [Streptozocin results in increased expression of TFRC mRNA] CTD PMID:22170771 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
decreases secretion
decreases expression
decreases methylation
multiple interactions
increases secretion		 ISO
EXP		 Streptozocin results in increased expression of TGFB1 mRNA; Streptozocin results in increased expression of TGFB1 protein
Streptozocin results in decreased secretion of TGFB1 protein
Streptozocin results in decreased expression of TGFB1 mRNA
Streptozocin results in decreased methylation of TGFB1 promoter
[ALPK1 protein results in increased susceptibility to Streptozocin] which results in increased expression of TGFB1 mRNA; [ALPK1 protein results in increased susceptibility to Streptozocin] which results in increased expression of TGFB1 protein
Streptozocin results in increased expression of TGFB1; Streptozocin results in increased expression of TGFB1 mRNA; Streptozocin results in increased expression of TGFB1 protein
1-hexacosanol inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Cadmium] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TGFB1 protein; [Streptozocin co-treated with Ramipril] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Resveratrol] results in increased expression of TGFB1 protein; ACE2 inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; baicalin inhibits the reaction [Streptozocin results in decreased expression of TGFB1 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Calcitriol inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Calcitriol inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; danggui buxue decoction inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TGFB1 protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TGFB1 protein]]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; esculetin inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Flavonoids inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; Gallic Acid inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; mangiferin inhibits the reaction [Streptozocin results in increased secretion of TGFB1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TGFB1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of TGFB1 protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; Pyridoxamine inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Thioctic Acid inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Trientine inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Vitamin E inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; XLF-III-43 inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; zingerone inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 mRNA]; 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 protein]; 3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein; [fatostatin co-treated with Streptozocin] results in increased expression of TGFB1 mRNA; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TGFB1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 protein; bisphenol A inhibits the reaction [Streptozocin results in decreased secretion of TGFB1 protein]; CEBPB protein affects the reaction [Streptozocin results in increased expression of TGFB1 protein]; Chlorpyrifos inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 mRNA]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 protein]; Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; sarpogrelate inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]		 CTD PMID:11798641 PMID:12660331 PMID:14586741 PMID:15309289 PMID:16409969 More... NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 multiple interactions
increases expression
affects expression		 EXP
ISO		 benazepril inhibits the reaction [Streptozocin results in increased expression of TGFBR1 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of TGFBR1 protein]
fatostatin inhibits the reaction [Streptozocin results in increased expression of TGFBR1 mRNA]
Streptozocin affects the expression of TGFBR1 mRNA
Streptozocin results in increased expression of TGFBR1 mRNA; Streptozocin results in increased expression of TGFBR1 protein		 CTD PMID:11798618 PMID:26073000 PMID:29420703 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 decreases expression ISO Streptozocin results in decreased expression of TGFBR2 protein CTD PMID:15496156 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 multiple interactions EXP [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in decreased expression of TGFBR3 protein CTD PMID:31062909 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341 		JBrowse link
G Th tyrosine hydroxylase multiple interactions
decreases expression		 EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of TH protein; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TH protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of TH protein] CTD PMID:35085591 PMID:38049026 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Thbd thrombomodulin multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of THBD mRNA CTD PMID:25905778 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193 		JBrowse link
G Thbs1 thrombospondin 1 multiple interactions
increases expression		 EXP pioglitazone inhibits the reaction [Streptozocin results in increased expression of THBS1 mRNA]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of THBS1 protein]
Streptozocin results in increased expression of THBS1 mRNA; Streptozocin results in increased expression of THBS1 protein		 CTD PMID:17063547 PMID:17117553 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Thbs2 thrombospondin 2 increases expression ISO Streptozocin results in increased expression of THBS2 protein CTD PMID:23723366 NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789 		JBrowse link
G Thbs4 thrombospondin 4 multiple interactions
increases expression		 EXP vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of THBS4 mRNA] CTD PMID:16684804 NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313 		JBrowse link
G Thrsp thyroid hormone responsive multiple interactions
decreases expression		 EXP
ISO		 Fructose inhibits the reaction [Streptozocin results in decreased expression of THRSP mRNA]
[Streptozocin co-treated with Dietary Fats] results in decreased expression of THRSP mRNA		 CTD PMID:2177838 PMID:29127188 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075 		JBrowse link
G Timm8b translocase of inner mitochondrial membrane 8 homolog B affects expression ISO Streptozocin affects the expression of TIMM8B mRNA CTD PMID:18583417 NCBI chr 8:50,954,350...50,955,730
Ensembl chr 8:50,954,342...50,955,729 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
decreases expression
increases activity
multiple interactions		 EXP Streptozocin results in increased expression of TIMP1 mRNA
Streptozocin results in decreased expression of TIMP1 mRNA
Streptozocin results in increased activity of TIMP1 protein
[Resveratrol co-treated with Streptozocin] results in increased expression of TIMP1 mRNA; Olive Oil promotes the reaction [Streptozocin results in increased activity of TIMP1 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of TIMP1 mRNA]		 CTD PMID:18246672 PMID:25246140 PMID:25905778 PMID:32662907 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression
increases secretion
multiple interactions
increases activity		 EXP
ISO		 Streptozocin results in increased expression of TIMP2 mRNA; Streptozocin results in increased expression of TIMP2 protein
Streptozocin results in increased secretion of TIMP2 protein
Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in increased expression of TIMP2 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in increased secretion of TIMP2 protein]
Streptozocin results in increased activity of TIMP2 protein
benazepril inhibits the reaction [Streptozocin results in increased expression of TIMP2 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of TIMP2 protein]; Olive Oil promotes the reaction [Streptozocin results in increased activity of TIMP2 protein]		 CTD PMID:16732983 PMID:20821936 PMID:23471663 PMID:25246140 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
G Tinag tubulointerstitial nephritis antigen increases expression
multiple interactions		 EXP Streptozocin results in increased expression of TINAG protein
Trientine inhibits the reaction [Streptozocin results in increased expression of TINAG protein]		 CTD PMID:19634143 NCBI chr 8:77,800,031...77,885,077
Ensembl chr 8:77,800,032...77,885,077 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
decreases expression		 ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP1 protein; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP1 protein]; rhodioloside inhibits the reaction [Streptozocin results in decreased expression of TJP1 protein] CTD PMID:27783111 PMID:31682803 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tjp2 tight junction protein 2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP2 protein; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP2 protein] CTD PMID:27783111 NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295 		JBrowse link
G Tkt transketolase multiple interactions EXP [benphothiamine co-treated with Streptozocin] results in increased activity of TKT protein CTD PMID:12592403 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698 		JBrowse link
G Tlr3 toll-like receptor 3 multiple interactions
increases expression		 ISO TNF protein inhibits the reaction [Streptozocin results in increased expression of TLR3 mRNA] CTD PMID:20446767 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions
increases expression		 ISO
EXP		 TNF protein inhibits the reaction [Streptozocin results in increased expression of TLR4 mRNA]
Streptozocin results in increased expression of TLR4 mRNA; Streptozocin results in increased expression of TLR4 protein
crocin inhibits the reaction [Streptozocin results in increased expression of TLR4 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TLR4 protein]; myrtenol inhibits the reaction [Streptozocin results in increased expression of TLR4 mRNA]; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of TLR4 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of TLR4 protein]
[Dietary Fats co-treated with Streptozocin] results in increased expression of TLR4 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TLR4 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TLR4 protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TLR4 mRNA]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TLR4 protein]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TLR4 mRNA]		 CTD PMID:20446767 PMID:27769711 PMID:29409856 PMID:34477272 PMID:36504472 More... NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tmed3 transmembrane p24 trafficking protein 3 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of TMED3 mRNA CTD PMID:25905778 NCBI chr 8:90,241,516...90,249,429
Ensembl chr 8:90,241,516...90,249,346 		JBrowse link
G Tmsb10 thymosin, beta 10 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of TMSB10 mRNA CTD PMID:25905778 NCBI chr 4:105,009,959...105,011,095
Ensembl chr 4:105,009,212...105,011,028 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
decreases expression
increases secretion		 ISO
EXP		 PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; TNF protein inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; TNF protein inhibits the reaction [Streptozocin results in increased expression of TLR3 mRNA]; TNF protein inhibits the reaction [Streptozocin results in increased expression of TLR4 mRNA]; TNF protein inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; TNF protein inhibits the reaction [Streptozocin results in increased expression of TNFRSF1B mRNA]
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; 4-methyl-2-((2-methylbenzyl) amino)-1,3-thiazole-5-carboxylic acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; [Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of TNF mRNA; [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of TNF protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein; [Niacinamide co-treated with Streptozocin] results in increased expression of TNF protein; [pimagedine co-treated with Fatty Acids, Omega-3] inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of TNF protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein; [Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TNF protein; [Streptozocin co-treated with Fructose] results in increased expression of TNF protein; [Streptozocin co-treated with Niacinamide] results in increased expression of TNF protein; [Telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of TNF protein]; [Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; caffeic acid phenethyl ester inhibits the reaction [Streptozocin results in increased expression of TNF protein]; caryophyllene inhibits the reaction [Streptozocin results in increased expression of TNF protein]; chromium nicotinic acid complex inhibits the reaction [Streptozocin results in increased secretion of TNF protein]; cloricromen inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of TNF protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TNF protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TNF protein]]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of TNF protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TNF protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of TNF protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of TNF protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of TNF protein]; mangiferin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Melatonin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TNF protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of TNF protein]]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; myrtenol inhibits the reaction [Streptozocin results in increased expression of TNF protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Ozone inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Phycocyanin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; picolinic acid inhibits the reaction [Streptozocin results in increased secretion of TNF protein]; pinitol inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of TNF protein]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Pyridoxamine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of TNF protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TNF protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of TNF protein]; rhapontin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Rivastigmine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; SMe1EC2 promotes the reaction [Streptozocin results in increased expression of TNF protein]; sodium arsenate promotes the reaction [Streptozocin results in increased expression of TNF protein]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of TNF mRNA]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of TNF protein]; Streptozocin results in increased expression of and results in increased secretion of TNF protein; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Thioctic Acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]
Streptozocin results in increased expression of TNF mRNA; Streptozocin results in increased expression of TNF protein
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TNF mRNA]; 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TNF protein]; 3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of TNF protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein; [Streptozocin co-treated with bisphenol A] results in increased expression of TNF mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of TNF mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of TNF protein; [Streptozocin co-treated with Niacinamide] results in increased expression of TNF mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of TNF protein; [Streptozocin co-treated with octylphenol] results in increased expression of TNF mRNA; [Streptozocin co-treated with Particulate Matter] results in increased expression of TNF protein; [Streptozocin co-treated with Vehicle Emissions] results in increased expression of TNF protein; Acrylamide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Alendronate inhibits the reaction [Streptozocin results in increased expression of TNF protein]; AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF protein]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; asiatic acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of TNF protein]; Carnosine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Carnosine promotes the reaction [asiatic acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Donepezil inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Dronabinol inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; etiron promotes the reaction [Streptozocin results in increased expression of TNF protein]; Genistein inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of TNF protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TNF mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TNF protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; montelukast inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]		 CTD PMID:11357882 PMID:12123627 PMID:15309289 PMID:15862027 PMID:15892581 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip1 TNF alpha induced protein 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of TNFAIP1 mRNA CTD PMID:20665664 NCBI chr10:63,417,774...63,432,466
Ensembl chr10:63,417,775...63,432,466 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B decreases expression EXP Streptozocin results in decreased expression of TNFRSF11B mRNA CTD PMID:25617479 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B multiple interactions
increases expression		 ISO TNF protein inhibits the reaction [Streptozocin results in increased expression of TNFRSF1B mRNA] CTD PMID:20446767 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of TNFRSF8 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TNFRSF8 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNFRSF8 mRNA] CTD PMID:33484791 NCBI chr 5:157,123,183...157,168,421
Ensembl chr 5:157,123,185...157,168,421 		JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of TNFRSF9 mRNA CTD PMID:33484791 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000 		JBrowse link
G Tomm40 translocase of outer mitochondrial membrane 40 affects expression ISO Streptozocin affects the expression of TOMM40 mRNA CTD PMID:18583417 NCBI chr 1:79,358,781...79,370,882
Ensembl chr 1:79,358,786...79,370,915 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression		 ISO
EXP		 2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of TRP53 mRNA]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53 protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53]
Streptozocin results in increased expression of TP53 mRNA; Streptozocin results in increased expression of TP53 protein
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of TP53 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of TP53 protein; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TP53 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TP53 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of TP53 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of TP53 protein]
Streptozocin results in increased expression of TRP53; Streptozocin results in increased expression of TRP53 mRNA; Streptozocin results in increased expression of TRP53 protein		 CTD PMID:11375343 PMID:15976052 PMID:22744176 PMID:23792339 PMID:29059224 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tph2 tryptophan hydroxylase 2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of TPH2 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of TPH2 mRNA] CTD PMID:32303808 NCBI chr 7:50,685,694...50,789,424
Ensembl chr 7:50,685,694...50,789,424 		JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions
increases expression		 EXP
ISO		 Glyburide inhibits the reaction [Streptozocin results in increased expression of TRAF6 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of TRAF6 protein]
[Streptozocin co-treated with Dietary Fats] results in increased expression of TRAF6 mRNA; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TRAF6 mRNA]		 CTD PMID:36504472 PMID:37482253 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Trat1 T cell receptor associated transmembrane adaptor 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of TRAT1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TRAT1 mRNA] CTD PMID:33484791 NCBI chr11:52,035,750...52,077,805
Ensembl chr11:52,035,750...52,077,805 		JBrowse link
G Treh trehalase multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of TREH mRNA CTD PMID:29127188 NCBI chr 8:44,990,182...45,003,881
Ensembl chr 8:44,990,182...45,003,540 		JBrowse link
G Trh thyrotropin releasing hormone decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of TRH mRNA
TRH protein inhibits the reaction [Streptozocin inhibits the reaction [Blood Glucose results in increased secretion of INS1 protein]]		 CTD PMID:16118471 NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637 		JBrowse link
G Trib3 tribbles pseudokinase 3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of TRIB3 mRNA CTD PMID:29127188 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of TRPM4 mRNA CTD PMID:29127188 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 increases response to substance EXP TRPV4 protein results in increased susceptibility to Streptozocin CTD PMID:18234883 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
G Trpv5 transient receptor potential cation channel, subfamily V, member 5 decreases expression
multiple interactions		 ISO Streptozocin results in decreased expression of TRPV5 mRNA
formononetin inhibits the reaction [Streptozocin results in decreased expression of TRPV5 mRNA]		 CTD PMID:35315182 NCBI chr 4:70,536,432...70,562,743
Ensembl chr 4:70,536,440...70,562,745 		JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 multiple interactions
decreases expression		 ISO [bisphenol A co-treated with Streptozocin] results in increased expression of TRPV6 mRNA; [Ethinyl Estradiol co-treated with Streptozocin] results in increased expression of TRPV6 mRNA; formononetin inhibits the reaction [Streptozocin results in decreased expression of TRPV6 mRNA] CTD PMID:29935216 PMID:35315182 NCBI chr 4:70,507,347...70,523,013
Ensembl chr 4:70,507,348...70,523,017 		JBrowse link
G Tsc22d1 TSC22 domain family, member 1 decreases expression EXP Streptozocin results in decreased expression of TSC22D1 mRNA CTD PMID:25905778 NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958 		JBrowse link
G Tspan8 tetraspanin 8 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of TSPAN8 mRNA CTD PMID:25905778 NCBI chr 7:51,444,946...51,479,360
Ensembl chr 7:51,445,074...51,479,356 		JBrowse link
G Tspo translocator protein multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of TSPO mRNA CTD PMID:25905778 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450 		JBrowse link
G Ttll8 tubulin tyrosine ligase like 8 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of TTLL8 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TTLL8 mRNA] CTD PMID:33484791 NCBI chr 7:120,000,638...120,046,556
Ensembl chr 7:120,001,794...120,045,075 		JBrowse link
G Ttr transthyretin decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of TTR protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of TTR protein]		 CTD PMID:19634143 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
G Txn1 thioredoxin 1 multiple interactions ISO TXN protein inhibits the reaction [Streptozocin results in increased secretion of ALB protein] CTD PMID:17360766 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Txnip thioredoxin interacting protein increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of TXNIP mRNA
[Streptozocin co-treated with Dietary Fats] results in increased expression of TXNIP protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TXNIP protein]
Streptozocin results in increased expression of TXNIP mRNA; Streptozocin results in increased expression of TXNIP protein
Allopurinol inhibits the reaction [Streptozocin results in increased expression of TXNIP mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of TXNIP protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of TXNIP mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of TXNIP protein]		 CTD PMID:17582205 PMID:23647015 PMID:35961541 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression EXP Streptozocin results in increased expression of TXNRD1 mRNA CTD PMID:12398930 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of TYROBP mRNA CTD PMID:25905778 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 multiple interactions
increases expression		 EXP 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of UBA1 protein] CTD PMID:30980806 NCBI chr  X:1,508,700...1,530,677
Ensembl chr  X:1,508,666...1,530,636 		JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 decreases expression
multiple interactions
increases expression		 EXP Streptozocin results in decreased expression of UCHL1 protein
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of UCHL1 protein]		 CTD PMID:30583000 PMID:30980806 NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590 		JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of UCHL5 protein
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of UCHL5 protein]		 CTD PMID:30980806 NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502 		JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of UCP2 mRNA CTD PMID:33359794 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
G Ucp3 uncoupling protein 3 increases expression ISO Streptozocin results in increased expression of UCP3 protein CTD PMID:16306367 NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762 		JBrowse link
G Uqcrb ubiquinol-cytochrome c reductase binding protein multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of UQCRB mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of UQCRB mRNA] CTD PMID:37337224 NCBI chr 7:63,814,784...63,820,150
Ensembl chr 7:63,814,797...63,820,150 		JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of UQCRC1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of UQCRC1 protein]		 CTD PMID:19634143 PMID:21136691 NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480 		JBrowse link
G Usp15 ubiquitin specific peptidase 15 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of USP15 mRNA; Streptozocin results in increased expression of USP15 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NFE2L2 protein inhibits the reaction [Streptozocin results in increased expression of USP15 protein]]; MIR497 inhibits the reaction [Streptozocin results in increased expression of USP15 mRNA]; MIR497 inhibits the reaction [Streptozocin results in increased expression of USP15 protein]; NFE2L2 protein inhibits the reaction [Streptozocin results in increased expression of USP15 protein]; USP15 protein inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; USP15 protein inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]		 CTD PMID:35478295 NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721 		JBrowse link
G Usp16 ubiquitin specific peptidase 16 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of USP16 mRNA; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of USP16 mRNA] CTD PMID:28946194 NCBI chr11:26,681,359...26,711,313
Ensembl chr11:26,681,414...26,710,539 		JBrowse link
G Usp2 ubiquitin specific peptidase 2 increases expression EXP Streptozocin results in increased expression of USP2 mRNA CTD PMID:25905778 NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331 		JBrowse link
G Usp22 ubiquitin specific peptidase 22 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of USP22 mRNA; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of USP22 mRNA] CTD PMID:28946194 NCBI chr10:45,828,619...45,855,468
Ensembl chr10:45,828,622...45,855,497 		JBrowse link
G Usp27x ubiquitin specific peptidase 27, X-linked increases expression
multiple interactions		 EXP Streptozocin results in increased expression of USP27X protein
baicalin inhibits the reaction [Streptozocin results in increased expression of USP27X protein]		 CTD PMID:34414639 NCBI chr  X:15,123,620...15,126,855
Ensembl chr  X:15,124,596...15,125,912 		JBrowse link
G Vamp2 vesicle-associated membrane protein 2 multiple interactions EXP [Streptozocin co-treated with Niacinamide] results in decreased expression of VAMP2 mRNA; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of VAMP2 mRNA] CTD PMID:25999625 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions
increases expression		 EXP
ISO		 [Streptozocin co-treated with Dietary Fats] results in increased expression of VCAM1 mRNA; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein]; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]; candesartan inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein]; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of VCAM1 mRNA]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]
[Streptozocin co-treated with Dietary Fats] results in increased expression of VCAM1 protein; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of VCAM1 protein]
Streptozocin results in increased expression of VCAM1 mRNA; Streptozocin results in increased expression of VCAM1 protein		 CTD PMID:16129698 PMID:16139267 PMID:16979161 PMID:17589825 PMID:24707343 More... NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vcp valosin-containing protein multiple interactions
increases expression		 EXP 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of VCP protein] CTD PMID:30980806 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of VDAC1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of VDAC1 protein]		 CTD PMID:19634143 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640 		JBrowse link
G Vdac2 voltage-dependent anion channel 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of VDAC2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of VDAC2 protein]		 CTD PMID:19634143 NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553 		JBrowse link
G Vdr vitamin D receptor decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of VDR mRNA; Streptozocin results in decreased expression of VDR protein
Calcitriol inhibits the reaction [Streptozocin results in decreased expression of VDR mRNA]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of VDR protein]		 CTD PMID:29953732 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
decreases secretion
increases expression
decreases expression		 ISO
EXP		 bisphenol A inhibits the reaction [Streptozocin results in decreased secretion of VEGFA protein]; dehydroxymethylepoxyquinomicin inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; dehydroxymethylepoxyquinomicin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]
Streptozocin results in increased expression of VEGFA mRNA; Streptozocin results in increased expression of VEGFA protein
Streptozocin results in decreased expression of VEGFA mRNA
[Streptozocin co-treated with Cadmium] results in increased expression of VEGFA protein; ACE2 inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; benazepril inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; cloricromen inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; manumycin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Melatonin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of VEGFA protein]; PD 123319 inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; PD 123319 inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Taurine inhibits the reaction [Streptozocin results in decreased expression of VEGFA mRNA]; Thioctic Acid inhibits the reaction [Streptozocin results in decreased expression of VEGFA mRNA]; turmeric extract inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; turmeric extract inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]		 CTD PMID:11596663 PMID:14718351 PMID:15643138 PMID:17662242 PMID:17724226 More... NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vegfc vascular endothelial growth factor C decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of VEGFC mRNA
baicalin inhibits the reaction [Streptozocin results in decreased expression of VEGFC mRNA]		 CTD PMID:34414639 NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848 		JBrowse link
G Vim vimentin multiple interactions
increases expression		 EXP carvedilol inhibits the reaction [Streptozocin results in increased expression of VIM protein] CTD PMID:12140129 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
G Vldlr very low density lipoprotein receptor multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of VLDLR mRNA CTD PMID:29127188 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920 		JBrowse link
G Vnn1 vanin 1 multiple interactions EXP [Streptozocin co-treated with Fructose] results in increased expression of VNN1 mRNA; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of VNN1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of VNN1 mRNA] CTD PMID:30551545 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395 		JBrowse link
G Vwa3b von Willebrand factor A domain containing 3B multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of VWA3B mRNA CTD PMID:33484791 NCBI chr 9:39,249,523...39,419,614
Ensembl chr 9:39,250,430...39,419,611 		JBrowse link
G Wdr31 WD repeat domain 31 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of WDR31 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of WDR31 mRNA] CTD PMID:33484791 NCBI chr 5:75,897,074...75,917,461
Ensembl chr 5:75,898,353...75,917,417 		JBrowse link
G Wdr35 WD repeat domain 35 increases expression EXP Streptozocin results in increased expression of WDR35 mRNA CTD PMID:20224876 NCBI chr 6:31,771,315...31,831,450
Ensembl chr 6:31,771,360...31,831,029 		JBrowse link
G Wee1 WEE1 G2 checkpoint kinase increases expression EXP Streptozocin results in increased expression of WEE1 mRNA CTD PMID:25905778 NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688 		JBrowse link
G Wnt3a Wnt family member 3A multiple interactions
decreases expression		 ISO 5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of WNT3A protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of WNT3A protein] CTD PMID:34428446 NCBI chr10:44,034,174...44,078,366
Ensembl chr10:44,034,194...44,078,324 		JBrowse link
G Wsb1 WD repeat and SOCS box-containing 1 decreases expression EXP Streptozocin results in decreased expression of WSB1 mRNA CTD PMID:25905778 NCBI chr10:64,202,761...64,219,039
Ensembl chr10:64,202,763...64,219,019 		JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions EXP
ISO		 [Streptozocin co-treated with Dietary Fats] results in decreased expression of XBP1 mRNA alternative form; Bilirubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of XBP1 mRNA alternative form]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of XBP1 protein alternative form]; Streptozocin results in increased expression of and results in increased secretion of XBP1 protein alternative form
[Dietary Fats co-treated with Streptozocin] results in increased splicing of XBP1 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased splicing of XBP1 mRNA]		 CTD PMID:27664441 PMID:33812996 PMID:37054934 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
G Xdh xanthine dehydrogenase multiple interactions
increases activity
increases expression
affects activity		 EXP [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in increased activity of XDH protein modified form; [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in increased expression of XDH mRNA; [Streptozocin affects the activity of XDH protein] which results in increased chemical synthesis of Hydrogen Peroxide; [Streptozocin co-treated with Chlorpyrifos] inhibits the reaction [Propolis results in decreased activity of XDH protein modified form]; [Streptozocin co-treated with Chlorpyrifos] inhibits the reaction [Propolis results in decreased expression of XDH mRNA]; [Streptozocin co-treated with Chlorpyrifos] results in increased activity of XDH protein modified form; [Streptozocin co-treated with Chlorpyrifos] results in increased expression of XDH mRNA; Allopurinol inhibits the reaction [[Streptozocin affects the activity of XDH protein] which results in increased chemical synthesis of Hydrogen Peroxide]; Allopurinol inhibits the reaction [Streptozocin affects the activity of XDH protein]; Chlorpyrifos promotes the reaction [Streptozocin results in increased expression of XDH mRNA]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in increased activity of XDH protein modified form]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in increased expression of XDH mRNA]; Propolis inhibits the reaction [Streptozocin results in increased activity of XDH protein modified form]; Propolis inhibits the reaction [Streptozocin results in increased expression of XDH mRNA]; Quercetin inhibits the reaction [[Streptozocin affects the activity of XDH protein] which results in increased chemical synthesis of Hydrogen Peroxide]; Quercetin inhibits the reaction [Streptozocin affects the activity of XDH protein]; Streptozocin inhibits the reaction [Propolis results in decreased activity of XDH protein modified form]; Streptozocin inhibits the reaction [Propolis results in decreased expression of XDH mRNA]; Streptozocin promotes the reaction [Chlorpyrifos results in increased activity of XDH protein modified form]; Streptozocin promotes the reaction [Chlorpyrifos results in increased expression of XDH mRNA] CTD PMID:23647015 PMID:31400774 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
G Xiap X-linked inhibitor of apoptosis increases expression EXP Streptozocin results in increased expression of XIAP protein CTD PMID:15976052 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
G Zdhhc23 zinc finger DHHC-type palmitoyltransferase 23 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of ZDHHC23 mRNA CTD PMID:25905778 NCBI chr11:56,718,702...56,735,063
Ensembl chr11:56,718,826...56,734,194 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 decreases expression
multiple interactions		 ISO Streptozocin results in decreased expression of ZEB2 mRNA
SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of ZEB2 mRNA]		 CTD PMID:27629361 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
G Zfp184 zinc finger protein 184 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ZFP184 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ZFP184 mRNA] CTD PMID:33484791 NCBI chr17:42,588,140...42,603,905
Ensembl chr17:42,566,796...42,603,815 		JBrowse link
G Zfp239 zinc finger protein 239 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of ZFP239 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ZFP239 mRNA] CTD PMID:33484791 NCBI chr 4:151,029,431...151,039,283
Ensembl chr 4:151,029,405...151,039,529 		JBrowse link
G Zpbp2 zona pellucida binding protein 2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of ZPBP2 mRNA CTD PMID:33484791 NCBI chr10:83,558,772...83,567,511
Ensembl chr10:83,559,016...83,567,508 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      biological role 19815
        antimicrobial agent 18166
          streptozocin 1116
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            heteroorganic entity 19492
                              organochalcogen compound 19255
                                organooxygen compound 19172
                                  carbon oxoacid 18641
                                    carboxylic acid 18638
                                      carboacyl group 17698
                                        univalent carboacyl group 17698
                                          carbamoyl group 17548
                                            carboxamide 17548
                                              monocarboxylic acid amide 15680
                                                urea 5580
                                                  ureas 5578
                                                    N-nitrosoureas 2117
                                                      streptozocin 1116
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