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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N-nitrosoureas
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Accession:CHEBI:76551 term browser browse the term
Definition:A nitroso compound that is any urea in which one of the nitrogens is substituted by a nitroso group


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carmustine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
multiple interactions
ISO Carmustine results in increased expression of ABCB1 protein
[MGMT protein co-treated with ABCB1 protein] results in decreased susceptibility to Carmustine
CTD PMID:11792417, PMID:15239124 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects response to substance ISO ABCC2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 affects response to substance ISO ABCG5 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207
JBrowse link
G Acer2 alkaline ceramidase 2 increases expression EXP Carmustine results in increased expression of ACER2 mRNA CTD PMID:16005536 NCBI chr 5:105,230,540...105,279,732
Ensembl chr 5:105,230,580...105,279,731
JBrowse link
G Acp3 acid phosphatase 3 decreases expression EXP Carmustine results in decreased expression of ACP3 mRNA CTD PMID:16005536 NCBI chr 8:112,838,574...112,884,062
Ensembl chr 8:112,834,707...112,884,077
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 decreases expression ISO Carmustine results in decreased expression of ACTC1 mRNA CTD PMID:15980968 NCBI chr 3:105,507,403...105,512,939
Ensembl chr 3:105,507,403...105,512,939
JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression ISO Carmustine results in decreased expression of ACTG2 mRNA CTD PMID:15980968 NCBI chr 4:115,215,160...115,239,746
Ensembl chr 4:115,215,060...115,239,723
JBrowse link
G Actn1 actinin, alpha 1 decreases expression ISO Carmustine results in decreased expression of ACTN1 mRNA CTD PMID:15980968 NCBI chr 6:103,376,557...103,470,497
Ensembl chr 6:103,375,799...103,470,555
JBrowse link
G Adam15 ADAM metallopeptidase domain 15 decreases expression ISO Carmustine results in decreased expression of ADAM15 mRNA CTD PMID:15980968 NCBI chr 2:188,661,831...188,672,337
Ensembl chr 2:188,661,699...188,672,247
JBrowse link
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 decreases expression ISO Carmustine results in decreased expression of ADAMTS4 mRNA CTD PMID:15980968 NCBI chr13:89,622,996...89,632,485
Ensembl chr13:89,622,632...89,634,419
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 decreases expression ISO Carmustine results in decreased expression of ADCYAP1 mRNA CTD PMID:15980968 NCBI chr 9:121,705,897...121,725,736
Ensembl chr 9:121,706,979...121,725,716
JBrowse link
G Adra1b adrenoceptor alpha 1B decreases expression ISO Carmustine results in decreased expression of ADRA1B mRNA CTD PMID:15980968 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644
JBrowse link
G Agr3 anterior gradient 3, protein disulphide isomerase family member affects response to substance ISO AGR3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 6:55,371,738...55,424,233
Ensembl chr 6:55,371,738...55,424,674
JBrowse link
G Agt angiotensinogen decreases response to substance ISO AGT protein mutant form results in decreased susceptibility to Carmustine; AGT protein results in decreased susceptibility to Carmustine CTD PMID:11034089 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B affects response to substance ISO AKR1B1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions
affects response to substance
EXP
ISO
Carmustine results in decreased phosphorylation of AKT1 protein
LCN2 protein promotes the reaction [Carmustine results in decreased phosphorylation of AKT1 protein]
AKT1 protein affects the susceptibility to Carmustine
CTD PMID:18430789, PMID:19860839 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 decreases expression ISO Carmustine results in decreased expression of AKT2 mRNA CTD PMID:15980968 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Alad aminolevulinate dehydratase decreases expression
multiple interactions
ISO Carmustine results in decreased expression of ALAD mRNA
[Cyclophosphamide co-treated with Carmustine co-treated with Etoposide] results in decreased activity of ALAD protein
CTD PMID:15980968, PMID:19162187 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 decreases expression EXP Carmustine results in decreased expression of ALAS2 mRNA CTD PMID:16005536 NCBI chr  X:23,167,576...23,187,356
Ensembl chr  X:23,167,696...23,187,341
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 affects response to substance ISO ALDH1A3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:127,302,920...127,337,828
Ensembl chr 1:127,301,128...127,337,882
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type affects response to substance
decreases expression
ISO
EXP
ALOX12 protein affects the susceptibility to Carmustine
Carmustine results in decreased expression of ALOX12 mRNA
CTD PMID:16005536, PMID:19373248 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G Alox15b arachidonate 15-lipoxygenase, type B decreases expression ISO Carmustine results in decreased expression of ALOX15B mRNA CTD PMID:15980968 NCBI chr10:55,773,748...55,783,489
Ensembl chr10:55,774,006...55,783,489
JBrowse link
G Amh anti-Mullerian hormone decreases expression ISO Carmustine results in decreased expression of AMH mRNA CTD PMID:15980968 NCBI chr 7:11,775,155...11,777,503
Ensembl chr 7:11,775,155...11,777,503
JBrowse link
G Ank2 ankyrin 2 affects response to substance ISO ANK2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 2:231,224,643...231,522,655
Ensembl chr 2:231,226,949...231,648,122
JBrowse link
G Ankrd1 ankyrin repeat domain 1 affects response to substance ISO ANKRD1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:254,726,985...254,745,673
Ensembl chr 1:254,726,969...254,735,548
JBrowse link
G Ap1s2 adaptor related protein complex 1 subunit sigma 2 affects response to substance ISO AP1S2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr  X:32,329,883...32,376,301
Ensembl chr  X:32,329,598...32,355,307
JBrowse link
G Apc APC regulator of WNT signaling pathway affects response to substance ISO APC mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 decreases expression ISO Carmustine results in decreased expression of APC2 mRNA CTD PMID:15980968 NCBI chr 7:12,258,468...12,280,459
Ensembl chr 7:12,258,468...12,275,609
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases response to substance
decreases response to substance
ISO APEX1 protein mutant form results in increased susceptibility to Carmustine
APEX1 protein results in decreased susceptibility to Carmustine
CTD PMID:12231548, PMID:16243814, PMID:17259346, PMID:19470598 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Aplnr apelin receptor decreases expression ISO Carmustine results in decreased expression of APLNR mRNA CTD PMID:15980968 NCBI chr 3:72,540,538...72,544,183
Ensembl chr 3:72,540,538...72,544,182
JBrowse link
G Aqp8 aquaporin 8 decreases expression ISO Carmustine results in decreased expression of AQP8 mRNA CTD PMID:15980968 NCBI chr 1:193,424,818...193,430,665
Ensembl chr 1:193,424,812...193,430,676
JBrowse link
G Arf1 ADP-ribosylation factor 1 affects response to substance ISO ARF1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr10:45,562,700...45,579,214
Ensembl chr10:45,563,547...45,579,029
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases expression EXP Carmustine results in decreased expression of ARNTL mRNA CTD PMID:16005536 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 decreases expression ISO Carmustine results in decreased expression of ARPC2 mRNA CTD PMID:15980968 NCBI chr 9:81,518,163...81,548,871
Ensembl chr 9:81,518,176...81,548,871
JBrowse link
G Arrdc2 arrestin domain containing 2 affects response to substance ISO ARRDC2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr16:20,352,480...20,356,612
Ensembl chr16:20,352,480...20,356,612
JBrowse link
G Artn artemin decreases expression ISO Carmustine results in decreased expression of ARTN mRNA CTD PMID:15980968 NCBI chr 5:136,759,717...136,765,036
Ensembl chr 5:136,759,717...136,762,986
JBrowse link
G Asmtl acetylserotonin O-methyltransferase-like decreases expression ISO Carmustine results in decreased expression of ASMTL mRNA CTD PMID:15980968 NCBI chr12:18,532,090...18,534,761
Ensembl chr12:18,531,990...18,534,836
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 decreases expression ISO Carmustine results in decreased expression of ATP1A3 mRNA CTD PMID:15980968 NCBI chr 1:81,852,423...81,881,565
Ensembl chr 1:81,852,429...81,881,549
JBrowse link
G Atp4b ATPase H+/K+ transporting subunit beta decreases expression ISO Carmustine results in decreased expression of ATP4B mRNA CTD PMID:15980968 NCBI chr16:81,136,218...81,145,131
Ensembl chr16:81,136,218...81,145,131
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta decreases expression ISO Carmustine results in decreased expression of ATP5F1D mRNA CTD PMID:15980968 NCBI chr 7:12,426,807...12,432,120
Ensembl chr 7:12,426,809...12,432,130
JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C decreases expression ISO Carmustine results in decreased expression of ATP6V0C mRNA CTD PMID:15980968 NCBI chr10:13,537,031...13,543,407
Ensembl chr10:13,537,033...13,542,077
JBrowse link
G Atr ATR serine/threonine kinase multiple interactions ISO ATR protein affects the reaction [Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein] CTD PMID:19261750 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947
JBrowse link
G Atxn2l ataxin 2-like decreases expression ISO Carmustine results in decreased expression of ATXN2L mRNA CTD PMID:15980968 NCBI chr 1:197,908,087...197,920,400
Ensembl chr 1:197,908,094...197,919,560
JBrowse link
G Avpr1a arginine vasopressin receptor 1A increases expression ISO Carmustine results in increased expression of AVPR1A mRNA CTD PMID:15980968 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G B4galt5 beta-1,4-galactosyltransferase 5 decreases expression ISO Carmustine results in decreased expression of B4GALT5 mRNA CTD PMID:15980968 NCBI chr 3:164,039,731...164,055,561
Ensembl chr 3:164,039,731...164,095,878
JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 decreases expression ISO Carmustine results in decreased expression of BAIAP2 mRNA CTD PMID:15980968 NCBI chr10:109,107,326...109,187,458
Ensembl chr10:109,107,389...109,187,115
JBrowse link
G Baiap3 BAI1-associated protein 3 decreases expression ISO Carmustine results in decreased expression of BAIAP3 mRNA CTD PMID:15980968 NCBI chr10:14,601,133...14,613,881
Ensembl chr10:14,599,197...14,613,878
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Carmustine results in increased expression of BAX protein CTD PMID:20920327 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl10 BCL10, immune signaling adaptor increases expression ISO Carmustine results in increased expression of BCL10 mRNA CTD PMID:15980968 NCBI chr 2:251,805,392...251,814,957
Ensembl chr 2:251,805,392...251,814,957
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
affects response to substance
decreases expression
ISO [Fenretinide co-treated with Carmustine] results in decreased expression of BCL2 protein
BCL2 protein affects the susceptibility to Carmustine
Carmustine results in decreased expression of BCL2 protein
CTD PMID:15332326, PMID:16187019, PMID:18430789, PMID:20920327 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 affects response to substance
decreases expression
multiple interactions
ISO
EXP
BCL2L1 protein affects the susceptibility to Carmustine
Carmustine results in decreased expression of BCL2L1 protein
[Fenretinide co-treated with Carmustine] results in decreased expression of BCL2L1 protein
Carmustine results in decreased expression of BCL2L1 mRNA; Carmustine results in decreased expression of BCL2L1 protein
CTD PMID:15332326, PMID:16187019, PMID:19860839 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Becn1 beclin 1 decreases expression ISO Carmustine results in decreased expression of BECN1 mRNA CTD PMID:15980968 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bicd1 BICD cargo adaptor 1 decreases expression ISO Carmustine results in decreased expression of BICD1 mRNA CTD PMID:15980968 NCBI chr 4:184,018,845...184,167,628
Ensembl chr 4:184,019,087...184,165,540
JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase decreases expression ISO Carmustine results in decreased expression of BLK mRNA CTD PMID:15980968 NCBI chr15:46,555,552...46,593,778
Ensembl chr15:46,555,188...46,593,653
JBrowse link
G Bmp5 bone morphogenetic protein 5 affects response to substance ISO BMP5 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 8:82,669,466...82,950,273
Ensembl chr 8:82,878,941...82,950,273
JBrowse link
G Bmp7 bone morphogenetic protein 7 decreases expression ISO Carmustine results in decreased expression of BMP7 mRNA CTD PMID:15980968 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Brf1 BRF1, RNA polymerase III transcription initiation factor subunit decreases expression ISO Carmustine results in decreased expression of BRF1 mRNA CTD PMID:15980968 NCBI chr 6:137,762,230...137,808,573
Ensembl chr 6:137,765,122...137,808,303
JBrowse link
G Ca6 carbonic anhydrase 6 decreases expression ISO Carmustine results in decreased expression of CA6 mRNA CTD PMID:15980968 NCBI chr 5:167,226,246...167,244,786
Ensembl chr 5:167,226,246...167,244,786
JBrowse link
G Cadm1 cell adhesion molecule 1 affects response to substance ISO CADM1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 8:51,858,906...52,200,591
Ensembl chr 8:52,127,399...52,189,722
JBrowse link
G Calb2 calbindin 2 decreases expression ISO Carmustine results in decreased expression of CALB2 mRNA CTD PMID:15980968 NCBI chr19:41,482,743...41,509,617
Ensembl chr19:41,482,728...41,509,658
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases cleavage
increases expression
EXP
ISO
Carmustine results in increased activity of CASP3 protein
[Carmustine co-treated with 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid] results in increased activity of CASP3 protein; Disulfiram promotes the reaction [Carmustine results in increased cleavage of CASP3 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Carmustine results in increased activity of and results in increased cleavage of CASP3 protein]; [LCN2 protein co-treated with Carmustine] results in increased cleavage of and results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [Carmustine results in increased activity of and results in increased cleavage of CASP3 protein]; Carmustine results in increased activity of and results in increased cleavage of CASP3 protein; pyrazolanthrone inhibits the reaction [Carmustine results in increased activity of and results in increased cleavage of CASP3 protein]; Zinc Sulfate inhibits the reaction [Carmustine results in increased activity of CASP3 protein]
Carmustine results in increased expression of CASP3 protein
CTD PMID:18590702, PMID:19860839, PMID:20046642, PMID:20920327, PMID:21600974, PMID:24193513 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase decreases activity
multiple interactions
EXP Carmustine results in decreased activity of CAT protein
Acetylcysteine inhibits the reaction [Carmustine results in decreased activity of CAT protein]
CTD PMID:20332008 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 affects activity
affects response to substance
increases expression
decreases expression
ISO Carmustine affects the activity of CCL2 protein
CCL2 mRNA affects the susceptibility to Carmustine
Carmustine results in increased expression of CCL2 mRNA
Carmustine results in decreased expression of CCL2 protein
CTD PMID:15980968, PMID:16365179, PMID:17522861 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccn4 cellular communication network factor 4 affects response to substance ISO CCN4 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 7:107,695,227...107,723,759
Ensembl chr 7:107,695,215...107,723,772
JBrowse link
G Ccnd1 cyclin D1 affects response to substance ISO CCND1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne1 cyclin E1 increases expression EXP Carmustine results in increased expression of CCNE1 mRNA CTD PMID:16005536 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cd151 CD151 molecule (Raph blood group) decreases expression ISO Carmustine results in decreased expression of CD151 mRNA CTD PMID:15980968 NCBI chr 1:214,446,659...214,450,668
Ensembl chr 1:214,009,784...214,013,765
Ensembl chr 1:214,009,784...214,013,765
JBrowse link
G Cd44 CD44 molecule (Indian blood group) affects response to substance ISO CD44 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd68 Cd68 molecule decreases expression ISO Carmustine results in decreased expression of CD68 mRNA CTD PMID:15980968 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
JBrowse link
G Cd79a CD79a molecule decreases expression ISO Carmustine results in decreased expression of CD79A mRNA CTD PMID:15980968 NCBI chr 1:81,763,609...81,768,039
Ensembl chr 1:81,763,614...81,767,980
JBrowse link
G Cd80 Cd80 molecule increases expression ISO Carmustine results in increased expression of CD80 mRNA CTD PMID:15980968 NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353
JBrowse link
G Cdc25b cell division cycle 25B decreases expression EXP Carmustine results in decreased expression of CDC25B mRNA CTD PMID:16005536 NCBI chr 3:123,731,539...123,741,696
Ensembl chr 3:123,731,539...123,741,339
JBrowse link
G Cdh13 cadherin 13 affects response to substance ISO CDH13 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr19:50,848,793...51,971,618
Ensembl chr19:50,848,736...51,972,103
JBrowse link
G Cdk8 cyclin-dependent kinase 8 decreases expression ISO Carmustine results in decreased expression of CDK8 mRNA CTD PMID:15980968 NCBI chr12:10,496,273...10,561,335 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO [Carmustine co-treated with O(6)-benzylguanine] results in increased expression of CDKN1A protein; MDM4 protein promotes the reaction [Carmustine results in increased expression of CDKN1A protein] CTD PMID:15735757, PMID:16193384, PMID:18632648, PMID:20472715 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C affects response to substance ISO CDKN1C mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:216,661,067...216,663,791
Ensembl chr 1:216,661,080...216,663,721
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases response to substance ISO CDKN2A protein results in increased susceptibility to Carmustine CTD PMID:16786135 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression EXP Carmustine results in decreased expression of CDKN3 mRNA CTD PMID:16005536 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
JBrowse link
G Cdx4 caudal type homeo box 4 decreases expression ISO Carmustine results in decreased expression of CDX4 mRNA CTD PMID:15980968 NCBI chr  X:74,165,172...74,173,758
Ensembl chr  X:74,165,187...74,173,347
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta decreases expression ISO Carmustine results in decreased expression of CEBPB mRNA CTD PMID:15980968 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 increases expression EXP Carmustine results in increased expression of CGREF1 mRNA CTD PMID:16005536 NCBI chr 6:26,797,126...26,809,132
Ensembl chr 6:26,797,126...26,809,129
JBrowse link
G Chd2 chromodomain helicase DNA binding protein 2 affects response to substance ISO CHD2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:134,757,934...134,873,053
Ensembl chr 1:134,757,934...134,871,167
JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO ATR protein affects the reaction [Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein]; Caffeine inhibits the reaction [Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein]; Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein; O(6)-benzylguanine promotes the reaction [Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein]; wortmannin inhibits the reaction [Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein] CTD PMID:19261750 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 decreases expression ISO Carmustine results in decreased expression of CHRM4 mRNA CTD PMID:15980968 NCBI chr 3:80,833,272...80,841,165
Ensembl chr 3:80,833,272...80,841,006
JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit decreases expression ISO Carmustine results in decreased expression of CHRNB3 mRNA CTD PMID:15980968 NCBI chr16:68,876,442...68,913,628
Ensembl chr16:68,875,709...68,913,628
JBrowse link
G Chrng cholinergic receptor nicotinic gamma subunit decreases expression ISO Carmustine results in decreased expression of CHRNG mRNA CTD PMID:15980968 NCBI chr 9:94,302,218...94,308,591 JBrowse link
G Ckm creatine kinase, M-type decreases expression ISO Carmustine results in decreased expression of CKM mRNA CTD PMID:15980968 NCBI chr 1:80,321,507...80,331,841
Ensembl chr 1:80,321,585...80,331,841
JBrowse link
G Clic1 chloride intracellular channel 1 multiple interactions
decreases response to substance
ISO [4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of CLIC1 protein] which results in increased susceptibility to Carmustine
CLIC1 protein results in decreased susceptibility to Carmustine
CTD PMID:18590702 NCBI chr20:5,040,314...5,049,166
Ensembl chr20:5,040,337...5,049,166
JBrowse link
G Cntnap1 contactin associated protein 1 increases expression ISO Carmustine results in increased expression of CNTNAP1 mRNA CTD PMID:15980968 NCBI chr10:89,087,904...89,103,615
Ensembl chr10:89,089,646...89,103,614
JBrowse link
G Col1a1 collagen type I alpha 1 chain affects response to substance ISO COL1A1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col5a3 collagen type V alpha 3 chain decreases expression EXP Carmustine results in decreased expression of COL5A3 mRNA CTD PMID:16005536 NCBI chr 8:21,786,324...21,831,751
Ensembl chr 8:21,786,324...21,831,668
JBrowse link
G Col9a1 collagen type IX alpha 1 chain decreases expression ISO Carmustine results in decreased expression of COL9A1 mRNA CTD PMID:15980968 NCBI chr 9:30,419,001...30,502,307
Ensembl chr 9:30,419,001...30,502,298
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 decreases expression ISO Carmustine results in decreased expression of COX6A2 mRNA CTD PMID:15980968 NCBI chr 1:199,624,037...199,626,255
Ensembl chr 1:199,624,037...199,624,783
JBrowse link
G Crabp1 cellular retinoic acid binding protein 1 decreases expression ISO Carmustine results in decreased expression of CRABP1 mRNA CTD PMID:15980968 NCBI chr 8:59,344,097...59,352,135
Ensembl chr 8:59,344,083...59,352,132
JBrowse link
G Crat carnitine O-acetyltransferase decreases expression ISO Carmustine results in decreased expression of CRAT mRNA CTD PMID:15980968 NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362
JBrowse link
G Crybb1 crystallin, beta B1 decreases expression ISO Carmustine results in decreased expression of CRYBB1 mRNA CTD PMID:15980968 NCBI chr12:50,390,939...50,404,550
Ensembl chr12:50,390,940...50,404,550
JBrowse link
G Csf2 colony stimulating factor 2 affects response to substance ISO CSF2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 affects response to substance ISO CSGALNACT1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr16:22,704,318...23,075,071
Ensembl chr16:22,979,444...23,074,798
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 affects response to substance ISO CSRP3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:104,147,205...104,166,389
Ensembl chr 1:104,147,206...104,166,367
JBrowse link
G Cst5 cystatin D decreases expression ISO Carmustine results in decreased expression of CST5 mRNA CTD PMID:15980968 NCBI chr 3:144,569,502...144,574,112
Ensembl chr 3:144,569,502...144,574,112
JBrowse link
G Ctf1 cardiotrophin 1 decreases expression ISO Carmustine results in decreased expression of CTF1 mRNA CTD PMID:15980968 NCBI chr 1:199,162,319...199,168,296
Ensembl chr 1:199,163,086...199,168,296
JBrowse link
G Ctnnal1 catenin alpha-like 1 increases expression ISO Carmustine results in increased expression of CTNNAL1 mRNA CTD PMID:15980968 NCBI chr 5:73,561,249...73,621,070
Ensembl chr 5:73,561,450...73,621,070
JBrowse link
G Ctsl cathepsin L increases expression EXP Carmustine results in increased expression of CTSL mRNA CTD PMID:16005536 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cux2 cut-like homeobox 2 affects expression EXP Carmustine affects the expression of CUX2 mRNA CTD PMID:19174181 NCBI chr12:40,016,774...40,221,067
Ensembl chr12:40,018,937...40,219,291
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 affects response to substance ISO CXCL1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 affects response to substance ISO CXCL2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 affects response to substance ISO CXCL1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression ISO Carmustine results in decreased expression of CYP19A1 mRNA CTD PMID:15980968 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO CYP3A5 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin] CTD PMID:16087946 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyth1 cytohesin 1 increases expression ISO Carmustine results in increased expression of CYTH1 mRNA CTD PMID:15980968 NCBI chr10:107,197,983...107,281,285
Ensembl chr10:107,197,989...107,281,235
JBrowse link
G Def6 DEF6 guanine nucleotide exchange factor affects response to substance ISO DEF6 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr20:7,788,120...7,809,011
Ensembl chr20:7,788,084...7,809,560
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 affects response to substance ISO DHRS3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:162,809,090...162,843,385
Ensembl chr 5:162,808,646...162,843,383
JBrowse link
G Dhx16 DEAH-box helicase 16 decreases expression ISO Carmustine results in decreased expression of DHX16 mRNA CTD PMID:15980968 NCBI chr20:3,368,971...3,386,087
Ensembl chr20:3,367,150...3,386,106
JBrowse link
G Dhx37 DEAH-box helicase 37 affects response to substance ISO DHX37 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr12:36,594,058...36,614,165
Ensembl chr12:36,594,047...36,614,210
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 increases response to substance ISO DKK1 protein results in increased susceptibility to Carmustine CTD PMID:20920327 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Dmrtc2 DMRT-like family C2 affects response to substance ISO DMRTC2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:81,734,256...81,741,419
Ensembl chr 1:81,736,335...81,741,345
JBrowse link
G Dnase1l2 deoxyribonuclease 1 like 2 decreases expression ISO Carmustine results in decreased expression of DNASE1L2 mRNA CTD PMID:15980968 NCBI chr10:13,812,335...13,814,514
Ensembl chr10:13,812,707...13,814,304
JBrowse link
G Dvl1 dishevelled segment polarity protein 1 decreases expression ISO Carmustine results in decreased expression of DVL1 mRNA CTD PMID:15980968 NCBI chr 5:173,295,948...173,308,014
Ensembl chr 5:173,296,270...173,307,945
JBrowse link
G Dyrk1b dual specificity tyrosine phosphorylation regulated kinase 1B affects response to substance ISO DYRK1B mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:85,112,819...85,120,840
Ensembl chr 1:85,112,247...85,120,839
JBrowse link
G E2f1 E2F transcription factor 1 increases expression ISO Carmustine results in increased expression of E2F1 protein CTD PMID:18632648 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Ecm2 extracellular matrix protein 2 increases expression ISO Carmustine results in increased expression of ECM2 mRNA CTD PMID:15980968 NCBI chr17:15,533,760...15,566,403
Ensembl chr17:15,533,972...15,566,332
JBrowse link
G Ednra endothelin receptor type A affects response to substance ISO EDNRA mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma increases expression ISO Carmustine results in increased expression of EEF1G mRNA CTD PMID:15980968 NCBI chr 1:225,163,391...225,173,997
Ensembl chr 1:225,163,391...225,173,995
JBrowse link
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha increases expression ISO Carmustine results in increased expression of EIF2B1 mRNA CTD PMID:15980968 NCBI chr12:37,444,136...37,452,391
Ensembl chr12:37,444,072...37,465,398
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 affects response to substance ISO EIF4A2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr11:81,373,047...81,379,680
Ensembl chr11:81,373,048...81,379,871
JBrowse link
G Eif6 eukaryotic translation initiation factor 6 decreases expression ISO Carmustine results in decreased expression of EIF6 mRNA CTD PMID:15980968 NCBI chr 3:151,356,867...151,363,201
Ensembl chr 3:151,356,868...151,363,115
JBrowse link
G Elmo1 engulfment and cell motility 1 affects response to substance ISO ELMO1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr17:46,352,102...46,888,788
Ensembl chr17:46,353,330...46,794,845
JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression EXP Carmustine results in increased expression of ENC1 mRNA CTD PMID:16005536 NCBI chr 2:28,049,217...28,061,023
Ensembl chr 2:28,049,217...28,061,029
JBrowse link
G Ephx1 epoxide hydrolase 1 decreases expression ISO Carmustine results in decreased expression of EPHX1 mRNA CTD PMID:15980968 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Espn espin increases expression EXP Carmustine results in increased expression of ESPN mRNA CTD PMID:16005536 NCBI chr 5:169,293,356...169,331,338
Ensembl chr 5:169,293,904...169,331,163
JBrowse link
G Esrra estrogen related receptor, alpha increases expression ISO Carmustine results in increased expression of ESRRA mRNA CTD PMID:15980968 NCBI chr 1:222,168,729...222,178,842
Ensembl chr 1:222,168,730...222,178,725
JBrowse link
G Etv1 ETS variant transcription factor 1 affects response to substance
affects expression
ISO
EXP
ETV1 mRNA affects the susceptibility to Carmustine
Carmustine affects the expression of ETV1 mRNA
CTD PMID:16365179, PMID:19174181 NCBI chr 6:58,467,215...58,558,640
Ensembl chr 6:58,467,254...58,558,631
JBrowse link
G Extl1 exostosin-like glycosyltransferase 1 affects response to substance ISO EXTL1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:152,573,755...152,588,956
Ensembl chr 5:152,573,758...152,589,719
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression ISO Carmustine results in decreased expression of EZH2 mRNA CTD PMID:15980968 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011
JBrowse link
G F3 coagulation factor III, tissue factor increases expression EXP Carmustine results in increased expression of F3 mRNA CTD PMID:16005536 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fancc FA complementation group C affects response to substance ISO FANCC mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr17:826,512...955,703
Ensembl chr17:833,509...955,615
JBrowse link
G Fancd2 FA complementation group D2 increases ubiquitination
affects localization
ISO Carmustine results in increased ubiquitination of FANCD2 protein
Carmustine affects the localization of FANCD2 protein
CTD PMID:17221219 NCBI chr 4:145,489,869...145,551,479
Ensembl chr 4:145,489,869...145,551,479
JBrowse link
G Fbln5 fibulin 5 decreases expression EXP Carmustine results in decreased expression of FBLN5 mRNA CTD PMID:16005536 NCBI chr 6:125,644,797...125,723,957
Ensembl chr 6:125,644,804...125,723,944
JBrowse link
G Fbn1 fibrillin 1 decreases expression ISO Carmustine results in decreased expression of FBN1 mRNA CTD PMID:15980968 NCBI chr 3:117,569,708...117,766,160
Ensembl chr 3:117,569,697...117,766,120
JBrowse link
G Fbxo32 F-box protein 32 affects response to substance ISO FBXO32 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 7:98,065,664...98,098,071
Ensembl chr 7:98,063,735...98,098,268
JBrowse link
G Fech ferrochelatase multiple interactions ISO [MGMT protein mutant form co-treated with FECH protein] results in decreased susceptibility to [O(6)-benzylguanine co-treated with Carmustine] CTD PMID:12950064 NCBI chr18:59,941,992...59,975,192
Ensembl chr18:59,941,992...59,975,192
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases response to substance ISO FGF2 protein results in decreased susceptibility to Carmustine CTD PMID:20221717 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fhl2 four and a half LIM domains 2 affects response to substance ISO FHL2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 9:49,920,611...49,994,906
Ensembl chr 9:49,920,854...49,950,093
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A decreases expression ISO Carmustine results in decreased expression of FKBP1A mRNA CTD PMID:15980968 NCBI chr 3:147,042,944...147,062,725
Ensembl chr 3:147,042,944...147,062,724
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 increases expression EXP Carmustine results in increased expression of FKBP5 mRNA CTD PMID:16005536 NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020
JBrowse link
G Fnta farnesyltransferase, CAAX box, alpha decreases expression
increases expression
ISO Carmustine results in decreased expression of FNTA mRNA
Carmustine results in increased expression of FNTA mRNA
CTD PMID:15980968 NCBI chr16:70,834,957...70,854,724
Ensembl chr16:70,834,957...70,854,724
JBrowse link
G Foxf2 forkhead box F2 affects response to substance ISO FOXF2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr17:34,150,417...34,156,450 JBrowse link
G Foxj1 forkhead box J1 decreases expression ISO Carmustine results in decreased expression of FOXJ1 mRNA CTD PMID:15980968 NCBI chr10:105,282,090...105,289,396 JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions
decreases response to substance
decreases expression
ISO Carmustine inhibits the reaction [3-O-caffeoyl-1-methylquinic acid results in increased expression of FTH1 mRNA]
FTH1 results in decreased susceptibility to Carmustine
Carmustine results in decreased expression of FTH1 mRNA
CTD PMID:15980968, PMID:16631525, PMID:21385903 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Ftl1 ferritin light chain 1 decreases expression ISO Carmustine results in decreased expression of FTL mRNA CTD PMID:15980968 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Fut8 fucosyltransferase 8 affects response to substance ISO FUT8 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 6:100,305,957...100,537,208
Ensembl chr 6:100,337,226...100,537,224
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase decreases expression ISO Carmustine results in decreased expression of FYN mRNA CTD PMID:15980968 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 decreases expression
affects response to substance
ISO Carmustine results in decreased expression of GABRA2 mRNA
GABRA2 mRNA affects the susceptibility to Carmustine
CTD PMID:15980968, PMID:16365179 NCBI chr14:39,662,411...39,801,082
Ensembl chr14:39,661,968...39,798,302
JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 decreases expression ISO Carmustine results in decreased expression of GABRA6 mRNA CTD PMID:15980968 NCBI chr10:27,847,447...27,862,896
Ensembl chr10:27,847,439...27,862,868
JBrowse link
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 affects response to substance ISO GALNT15 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr16:8,127,599...8,178,101
Ensembl chr16:8,128,689...8,177,841
JBrowse link
G Gamt guanidinoacetate N-methyltransferase decreases expression ISO Carmustine results in decreased expression of GAMT mRNA CTD PMID:15980968 NCBI chr 7:12,314,848...12,317,998
Ensembl chr 7:12,314,848...12,317,998
JBrowse link
G Garnl3 GTPase activating Rap/RanGAP domain-like 3 affects response to substance ISO GARNL3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 3:12,034,131...12,176,591
Ensembl chr 3:12,034,413...12,155,098
JBrowse link
G Gast gastrin decreases expression ISO Carmustine results in decreased expression of GAST mRNA CTD PMID:15980968 NCBI chr10:88,245,532...88,248,485
Ensembl chr10:88,245,532...88,248,484
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP [Buthionine Sulfoximine co-treated with Carmustine] results in decreased activity of GCLC protein; [Carmustine co-treated with Buthionine Sulfoximine] results in decreased activity of GCLC protein CTD PMID:12967637, PMID:16288907 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gcm1 glial cells missing transcription factor 1 increases expression ISO Carmustine results in increased expression of GCM1 mRNA CTD PMID:15980968 NCBI chr 8:85,355,766...85,369,002
Ensembl chr 8:85,355,766...85,369,002
JBrowse link
G Gdi1 GDP dissociation inhibitor 1 increases expression ISO Carmustine results in increased expression of GDI1 mRNA CTD PMID:15980968 NCBI chr  X:156,400,734...156,407,396
Ensembl chr  X:156,400,736...156,407,404
JBrowse link
G Gdi2 GDP dissociation inhibitor 2 increases expression ISO Carmustine results in increased expression of GDI2 mRNA CTD PMID:15980968 NCBI chr17:70,299,177...70,325,864
Ensembl chr17:70,299,183...70,325,855
JBrowse link
G Gdnf glial cell derived neurotrophic factor decreases response to substance ISO GDNF protein results in decreased susceptibility to Carmustine CTD PMID:19138852 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression
multiple interactions
ISO
EXP
Carmustine results in decreased expression of GFAP mRNA
Melatonin inhibits the reaction [Carmustine results in decreased expression of GFAP protein]
CTD PMID:15980968, PMID:17572393 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Ghsr growth hormone secretagogue receptor decreases expression ISO Carmustine results in decreased expression of GHSR mRNA CTD PMID:15980968 NCBI chr 2:113,065,953...113,071,265
Ensembl chr 2:113,066,885...113,070,261
JBrowse link
G Glrb glycine receptor, beta affects response to substance ISO GLRB mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 2:179,768,040...179,842,612
Ensembl chr 2:179,769,009...179,842,547
JBrowse link
G Gnrhr gonadotropin releasing hormone receptor increases expression ISO Carmustine results in increased expression of GNRHR mRNA CTD PMID:15980968 NCBI chr14:23,480,462...23,498,450
Ensembl chr14:23,480,462...23,498,450
JBrowse link
G Golga2 golgin A2 decreases expression ISO Carmustine results in decreased expression of GOLGA2 mRNA CTD PMID:15980968 NCBI chr 3:11,317,328...11,337,569
Ensembl chr 3:11,317,183...11,336,458
JBrowse link
G Golga4 golgin A4 increases expression ISO Carmustine results in increased expression of GOLGA4 mRNA CTD PMID:15980968 NCBI chr 8:127,171,221...127,248,938
Ensembl chr 8:127,171,537...127,248,538
JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta decreases expression ISO Carmustine results in decreased expression of GP1BB mRNA CTD PMID:15980968 NCBI chr11:86,520,992...86,522,169
Ensembl chr11:86,520,992...86,522,169
JBrowse link
G Gpr25 G protein-coupled receptor 25 decreases expression ISO Carmustine results in decreased expression of GPR25 mRNA CTD PMID:15980968 NCBI chr13:53,135,815...53,139,180
Ensembl chr13:53,136,174...53,137,253
JBrowse link
G Gpr32 G protein-coupled receptor 32 decreases expression ISO Carmustine results in decreased expression of GPR32 mRNA CTD PMID:15980968 NCBI chr 1:100,246,794...100,247,826 JBrowse link
G Gpr37 G protein-coupled receptor 37 decreases expression ISO Carmustine results in decreased expression of GPR37 mRNA CTD PMID:15980968 NCBI chr 4:51,822,163...51,844,228
Ensembl chr 4:51,822,153...51,844,331
JBrowse link
G Gpr65 G-protein coupled receptor 65 increases expression ISO Carmustine results in increased expression of GPR65 mRNA CTD PMID:15980968 NCBI chr 6:122,248,528...122,256,115
Ensembl chr 6:122,254,841...122,256,251
JBrowse link
G Grb7 growth factor receptor bound protein 7 decreases expression ISO Carmustine results in decreased expression of GRB7 mRNA CTD PMID:15980968 NCBI chr10:86,393,186...86,408,893
Ensembl chr10:86,399,827...86,409,348
JBrowse link
G Grn granulin precursor decreases expression ISO Carmustine results in decreased expression of GRN mRNA CTD PMID:15980968 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
ISO
EXP
[Carmustine results in decreased activity of GSR protein] which results in increased susceptibility to Doxorubicin; [Carmustine results in decreased activity of GSR protein] which results in increased susceptibility to zinc chloride; Glutathione Disulfide inhibits the reaction [Carmustine results in decreased activity of GSR protein]; NADP affects the reaction [Carmustine results in decreased activity of GSR protein]
[Buthionine Sulfoximine co-treated with Carmustine] results in decreased activity of GSR protein; [Carmustine co-treated with Buthionine Sulfoximine] results in decreased activity of GSR protein; [Carmustine results in decreased activity of GSR protein] which results in increased susceptibility to Streptozocin; [Carmustine results in decreased activity of GSR protein] which results in increased uptake of Calcium; MT2 protein inhibits the reaction [Carmustine results in decreased activity of GSR protein]; Zinc Sulfate inhibits the reaction [Carmustine results in decreased activity of GSR protein]
[[Carmustine results in decreased activity of GSR protein] which co-treated with Oligodeoxyribonucleotides analog] results in increased abundance of Glutathione Disulfide; [[Cyclophosphamide co-treated with Cisplatin co-treated with Carmustine] results in decreased activity of GSR protein] which results in increased abundance of Glutathione Disulfide; [Carmustine results in decreased activity of GSR protein] which results in decreased susceptibility to chromium hexavalent ion; [Cyclophosphamide co-treated with Cisplatin co-treated with Carmustine] results in decreased activity of GSR protein
CTD PMID:2116959, PMID:12114195, PMID:12433058, PMID:12477282, PMID:12632252, PMID:12967637, PMID:15104113, PMID:15321730, PMID:15720826, PMID:15857610, PMID:16160061, PMID:16288907, PMID:17382203, PMID:17498860, PMID:18155673, PMID:18528683, PMID:19401447, PMID:19668867, PMID:19856331, PMID:20046642, PMID:21600974 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance
decreases response to substance
multiple interactions
ISO GSTM1 gene affects the susceptibility to Carmustine
GSTM1 protein results in decreased susceptibility to Carmustine
GSTM1 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin]
CTD PMID:16087946, PMID:20067466 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases nitrosation ISO GSTM2 protein results in decreased nitrosation of Carmustine CTD PMID:11841793 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstm3 glutathione S-transferase mu 3 affects metabolic processing
decreases nitrosation
multiple interactions
ISO GSTM3 protein affects the metabolism of Carmustine
GSTM3 protein results in decreased nitrosation of Carmustine
GSTM3 protein results in decreased nitrosation of and results in decreased activity of Carmustine
CTD PMID:8395980, PMID:11841793, PMID:15247628 NCBI chr 2:210,685,204...210,688,273
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions
affects metabolic processing
decreases nitrosation
ISO GSTM3 protein results in decreased nitrosation of and results in decreased activity of Carmustine
GSTM3 protein affects the metabolism of Carmustine
GSTM3 protein results in decreased nitrosation of Carmustine
CTD PMID:8395980, PMID:11841793, PMID:15247628 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
decreases response to substance
ISO GSTP1 gene SNP results in increased susceptibility to [Carmustine co-treated with Doxorubicin co-treated with Cyclophosphamide co-treated with Melphalan]
GSTP1 protein results in decreased susceptibility to Carmustine
CTD PMID:12791655, PMID:16899598 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects response to substance
affects metabolic processing
decreases nitrosation
ISO GSTT1 protein affects the susceptibility to Carmustine
GSTT1 protein affects the metabolism of Carmustine
GSTT1 protein results in decreased nitrosation of Carmustine
CTD PMID:11841793, PMID:16874663, PMID:17827337 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Gtf2f1 general transcription factor IIF subunit 1 decreases expression ISO Carmustine results in decreased expression of GTF2F1 mRNA CTD PMID:15980968 NCBI chr 9:10,032,806...10,042,392
Ensembl chr 9:10,033,011...10,042,418
JBrowse link
G Gucy1b2 guanylate cyclase 1 soluble subunit beta 2 decreases expression EXP Carmustine results in decreased expression of GUCY1B2 mRNA CTD PMID:16005536 NCBI chr15:45,479,662...45,550,285
Ensembl chr15:45,479,658...45,550,285
JBrowse link
G H2ax H2A.X variant histone decreases expression
increases phosphorylation
multiple interactions
affects localization
ISO Carmustine results in decreased expression of H2AX mRNA
Carmustine results in increased phosphorylation of H2AX protein
MDM4 protein promotes the reaction [Carmustine affects the localization of H2AX protein]; MDM4 protein promotes the reaction [Carmustine results in increased phosphorylation of H2AX protein]
CTD PMID:15980968, PMID:20472715 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 decreases expression EXP Carmustine results in decreased expression of HACL1 mRNA CTD PMID:16005536 NCBI chr16:7,720,047...7,758,119
Ensembl chr16:7,714,465...7,758,189
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase decreases expression ISO Carmustine results in decreased expression of HADH mRNA CTD PMID:15980968 NCBI chr 2:236,353,445...236,395,067
Ensembl chr 2:236,353,445...236,395,067
JBrowse link
G Hagh hydroxyacyl glutathione hydrolase decreases expression ISO Carmustine results in decreased expression of HAGH mRNA CTD PMID:15980968 NCBI chr10:14,215,913...14,230,506
Ensembl chr10:14,216,155...14,230,515
JBrowse link
G Hcfc1 host cell factor C1 decreases expression ISO Carmustine results in decreased expression of HCFC1 mRNA CTD PMID:15980968 NCBI chr  X:156,812,012...156,837,227
Ensembl chr  X:156,812,064...156,837,227
JBrowse link
G Hhat hedgehog acyltransferase affects response to substance ISO HHAT mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr13:111,235,325...111,489,075
Ensembl chr13:111,236,466...111,474,411
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases response to substance
multiple interactions
EXP HIF1A protein results in decreased susceptibility to Carmustine
[cobaltous chloride results in increased activity of HIF1A protein] which results in decreased susceptibility to Carmustine; [Deferoxamine results in increased activity of HIF1A protein] which results in decreased susceptibility to Carmustine
CTD PMID:14980978, PMID:15965067 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmgn2 high mobility group nucleosomal binding domain 2 decreases expression ISO Carmustine results in decreased expression of HMGN2 mRNA CTD PMID:15980968 NCBI chr 5:152,195,359...152,198,813
Ensembl chr 5:152,195,361...152,198,813
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO Carmustine inhibits the reaction [3-O-caffeoyl-1-methylquinic acid results in increased expression of HMOX1 mRNA] CTD PMID:16631525 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf1a HNF1 homeobox A decreases expression ISO Carmustine results in decreased expression of HNF1A mRNA CTD PMID:15980968 NCBI chr12:47,407,811...47,433,342
Ensembl chr12:47,407,811...47,433,342
JBrowse link
G Hoxa4 homeo box A4 decreases expression ISO Carmustine results in decreased expression of HOXA4 mRNA CTD PMID:15980968 NCBI chr 4:82,158,234...82,160,317
Ensembl chr 4:82,158,892...82,160,240
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases mutagenesis ISO Carmustine results in increased mutagenesis of HPRT1 gene CTD PMID:17116724 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Icam5 intercellular adhesion molecule 5 decreases expression ISO Carmustine results in decreased expression of ICAM5 mRNA CTD PMID:15980968 NCBI chr 8:22,050,222...22,057,209
Ensembl chr 8:22,050,222...22,057,209
JBrowse link
G Ids iduronate 2-sulfatase decreases expression ISO Carmustine results in decreased expression of IDS mRNA CTD PMID:15980968 NCBI chr 8:69,447,971...69,466,708
Ensembl chr 8:69,449,801...69,466,618
JBrowse link
G Ier3 immediate early response 3 decreases expression ISO Carmustine results in decreased expression of IER3 mRNA CTD PMID:15980968 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression
increases expression
ISO Carmustine results in decreased expression of IGF1 protein
Carmustine results in increased expression of IGF1 protein
CTD PMID:15286697, PMID:18443378 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf2 insulin-like growth factor 2 affects response to substance ISO IGF2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression EXP Carmustine results in decreased expression of IGFBP3 mRNA CTD PMID:16005536 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma decreases expression ISO Carmustine results in decreased expression of IKBKG mRNA CTD PMID:15980968 NCBI chr  X:156,254,187...156,280,046
Ensembl chr  X:156,257,173...156,270,748
JBrowse link
G Il12b interleukin 12B multiple interactions ISO Carmustine promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:12688424 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Carmustine promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:11970852, PMID:12433058 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r1 interleukin 1 receptor type 1 affects response to substance ISO IL1R1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Il6 interleukin 6 affects response to substance
multiple interactions
ISO
EXP
IL6 mRNA affects the susceptibility to Carmustine
Carmustine promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
Carmustine promotes the reaction [Oligodeoxyribonucleotides analog results in increased secretion of IL6 protein]
CTD PMID:11970852, PMID:12433058, PMID:12477282, PMID:16365179 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Inhba inhibin subunit beta A affects response to substance ISO INHBA mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496
JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 decreases expression ISO Carmustine results in decreased expression of INPPL1 mRNA CTD PMID:15980968 NCBI chr 1:166,898,177...166,912,524
Ensembl chr 1:166,899,894...166,912,524
JBrowse link
G Insig1 insulin induced gene 1 decreases expression ISO Carmustine results in decreased expression of INSIG1 mRNA CTD PMID:15980968 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Insl3 insulin-like 3 decreases expression ISO Carmustine results in decreased expression of INSL3 mRNA CTD PMID:15980968 NCBI chr16:20,120,753...20,122,702
Ensembl chr16:20,121,352...20,122,696
JBrowse link
G Ipo4 importin 4 affects response to substance ISO IPO4 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr15:34,304,425...34,314,552
Ensembl chr15:34,304,425...34,314,345
JBrowse link
G Irag2 inositol 1,4,5-triphosphate receptor associated 2 decreases expression ISO Carmustine results in decreased expression of IRAG2 mRNA CTD PMID:15980968 NCBI chr 4:179,402,929...179,440,792
Ensembl chr 4:179,398,621...179,440,792
JBrowse link
G Irs1 insulin receptor substrate 1 decreases expression ISO Carmustine results in decreased expression of IRS1 mRNA CTD PMID:15980968 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Islr immunoglobulin superfamily containing leucine-rich repeat decreases expression ISO
EXP
Carmustine results in decreased expression of ISLR mRNA CTD PMID:15980968, PMID:16005536 NCBI chr 8:62,946,732...62,949,675
Ensembl chr 8:62,946,732...62,948,720
JBrowse link
G Itga3 integrin subunit alpha 3 decreases expression ISO Carmustine results in decreased expression of ITGA3 mRNA CTD PMID:15980968 NCBI chr10:82,855,841...82,887,755
Ensembl chr10:82,855,613...82,887,497
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO Carmustine results in decreased expression of ITGB1 protein CTD PMID:18443378 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Itgb3 integrin subunit beta 3 increases response to substance
multiple interactions
ISO
EXP
ITGB3 protein results in increased susceptibility to Carmustine
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [ITGB3 protein results in increased susceptibility to Carmustine]
CTD PMID:21332719 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 decreases expression ISO Carmustine results in decreased expression of ITIH1 mRNA CTD PMID:15980968 NCBI chr16:7,012,376...7,026,542
Ensembl chr16:7,012,354...7,026,540
JBrowse link
G Kcna4 potassium voltage-gated channel subfamily A member 4 multiple interactions EXP [Carmustine co-treated with Buthionine Sulfoximine] results in decreased expression of KCNA4 protein CTD PMID:16288907 NCBI chr 3:98,293,295...98,300,763
Ensembl chr 3:98,297,554...98,300,680
JBrowse link
G Kcnab2 potassium voltage-gated channel subfamily A regulatory beta subunit 2 affects response to substance ISO KCNAB2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:169,570,327...169,658,875
Ensembl chr 5:169,572,517...169,658,875
JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 multiple interactions EXP [Carmustine co-treated with Buthionine Sulfoximine] results in decreased expression of KCND2 mRNA; [Carmustine co-treated with Buthionine Sulfoximine] results in decreased expression of KCND2 protein CTD PMID:16288907 NCBI chr 4:48,309,283...48,816,804 JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases expression ISO Carmustine results in decreased expression of KCNH2 mRNA CTD PMID:15980968 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Kif2c kinesin family member 2C decreases expression EXP Carmustine results in decreased expression of KIF2C mRNA CTD PMID:16005536 NCBI chr 5:136,027,923...136,053,268
Ensembl chr 5:136,027,934...136,053,210
JBrowse link
G Kif5a kinesin family member 5A decreases expression ISO Carmustine results in decreased expression of KIF5A mRNA CTD PMID:15980968 NCBI chr 7:70,515,832...70,552,897
Ensembl chr 7:70,513,343...70,556,827
JBrowse link
G Krt17 keratin 17 decreases expression ISO Carmustine results in decreased expression of KRT17 mRNA CTD PMID:15980968 NCBI chr10:88,158,993...88,163,712
Ensembl chr10:88,118,001...88,163,723
JBrowse link
G Krt31 keratin 31 decreases expression ISO Carmustine results in decreased expression of KRT31 mRNA CTD PMID:15980968 NCBI chr10:87,959,123...87,962,891
Ensembl chr10:87,959,408...87,962,846
JBrowse link
G Krt8 keratin 8 affects response to substance ISO KRT8 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 7:143,596,511...143,603,745
Ensembl chr 7:143,596,511...143,603,803
JBrowse link
G Lad1 ladinin 1 decreases expression ISO Carmustine results in decreased expression of LAD1 mRNA CTD PMID:15980968 NCBI chr13:52,645,257...52,659,619
Ensembl chr13:52,645,257...52,659,619
JBrowse link
G Lair1 leukocyte-associated immunoglobulin-like receptor 1 increases expression ISO Carmustine results in increased expression of LAIR1 mRNA CTD PMID:15980968 NCBI chr 1:73,752,192...73,870,421
Ensembl chr 1:73,837,944...73,868,695
JBrowse link
G Lamb3 laminin subunit beta 3 decreases expression ISO Carmustine results in decreased expression of LAMB3 mRNA CTD PMID:15980968 NCBI chr13:112,031,614...112,073,187
Ensembl chr13:112,031,594...112,073,186
JBrowse link
G Lbp lipopolysaccharide binding protein affects response to substance ISO LBP mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 3:154,786,232...154,812,910
Ensembl chr 3:154,786,215...154,813,464
JBrowse link
G Lcn2 lipocalin 2 increases response to substance
multiple interactions
ISO
EXP
LCN2 protein results in increased susceptibility to Carmustine
[LCN2 protein co-treated with Carmustine] results in increased cleavage of and results in increased activity of CASP3 protein; LCN2 protein promotes the reaction [Carmustine results in decreased phosphorylation of AKT1 protein]
CTD PMID:19860839 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Ldlr low density lipoprotein receptor affects uptake ISO LDLR protein affects the uptake of Carmustine analog CTD PMID:12107554 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lif LIF, interleukin 6 family cytokine increases response to substance ISO LIF mRNA results in increased susceptibility to Carmustine CTD PMID:16365179 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Lig1 DNA ligase 1 decreases expression EXP Carmustine results in decreased expression of LIG1 mRNA CTD PMID:16005536 NCBI chr 1:75,356,212...75,394,757
Ensembl chr 1:75,356,220...75,394,758
JBrowse link
G Lins1 lines homolog 1 affects response to substance ISO LINS1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:127,599,647...127,625,583
Ensembl chr 1:127,604,197...127,625,577
JBrowse link
G Lman1l lectin, mannose-binding, 1 like affects response to substance ISO LMAN1L mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 8:62,386,806...62,400,370
Ensembl chr 8:62,386,806...62,399,648
JBrowse link
G Lmtk2 lemur tyrosine kinase 2 affects response to substance ISO LMTK2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr12:12,409,876...12,546,111
Ensembl chr12:12,409,876...12,546,111
JBrowse link
G Lmx1b LIM homeobox transcription factor 1 beta decreases expression ISO Carmustine results in decreased expression of LMX1B mRNA CTD PMID:15980968 NCBI chr 3:12,608,748...12,686,937
Ensembl chr 3:12,609,574...12,686,869
JBrowse link
G LOC691272 similar to reproductive homeobox on X chromosome, 11 decreases expression ISO Carmustine results in decreased expression of SHOX mRNA CTD PMID:15980968 NCBI chr  X:124,045,727...124,052,708
Ensembl chr  X:124,045,737...124,052,632
JBrowse link
G Loxl1 lysyl oxidase-like 1 decreases expression ISO Carmustine results in decreased expression of LOXL1 mRNA CTD PMID:15980968 NCBI chr 8:63,067,757...63,092,124
Ensembl chr 8:63,067,300...63,092,009
JBrowse link
G Lrch4 leucine rich repeats and calponin homology domain containing 4 decreases expression ISO Carmustine results in decreased expression of LRCH4 mRNA CTD PMID:15980968 NCBI chr12:22,127,387...22,138,436
Ensembl chr12:22,127,393...22,138,382
JBrowse link
G Lsp1 lymphocyte-specific protein 1 decreases expression EXP Carmustine results in decreased expression of LSP1 mRNA CTD PMID:16005536 NCBI chr 1:215,628,750...215,662,505
Ensembl chr 1:215,628,785...215,662,504
JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 decreases expression ISO Carmustine results in decreased expression of MAD1L1 mRNA CTD PMID:15980968 NCBI chr12:16,410,083...16,721,232
Ensembl chr12:16,410,083...16,719,824
JBrowse link
G Map4k2 mitogen activated protein kinase kinase kinase kinase 2 decreases expression ISO Carmustine results in decreased expression of MAP4K2 mRNA CTD PMID:15980968 NCBI chr 1:221,710,622...221,726,274
Ensembl chr 1:221,710,670...221,725,656
JBrowse link
G Mapk10 mitogen activated protein kinase 10 decreases expression ISO Carmustine results in decreased expression of MAPK10 mRNA CTD PMID:15980968 NCBI chr14:8,079,955...8,371,508
Ensembl chr14:8,080,275...8,368,254
JBrowse link
G Masp1 mannan-binding lectin serine peptidase 1 affects response to substance ISO MASP1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr11:80,736,424...80,806,278
Ensembl chr11:80,736,576...80,803,382
JBrowse link
G Mat1a methionine adenosyltransferase 1A decreases expression ISO Carmustine results in decreased expression of MAT1A mRNA CTD PMID:15980968 NCBI chr16:18,690,649...18,709,135
Ensembl chr16:18,690,246...18,709,133
JBrowse link
G Mdk midkine decreases expression ISO Carmustine results in decreased expression of MDK mRNA CTD PMID:15980968 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916
JBrowse link
G Mdm4 MDM4 regulator of p53 multiple interactions
decreases response to substance
ISO [Carmustine co-treated with MDM4 protein] results in increased expression of POLH protein; MDM4 protein promotes the reaction [Carmustine affects the localization of H2AX protein]; MDM4 protein promotes the reaction [Carmustine results in increased expression of CDKN1A protein]; MDM4 protein promotes the reaction [Carmustine results in increased expression of TP53 protein]; MDM4 protein promotes the reaction [Carmustine results in increased phosphorylation of H2AX protein]
MDM4 protein results in decreased susceptibility to Carmustine
CTD PMID:20472715 NCBI chr13:49,786,776...49,828,780
Ensembl chr13:49,792,794...49,828,720
JBrowse link
G Mecom MDS1 and EVI1 complex locus affects response to substance ISO EVI1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 2:117,396,084...117,993,604
Ensembl chr 2:117,396,007...117,454,769
JBrowse link
G Med1 mediator complex subunit 1 decreases expression ISO Carmustine results in decreased expression of MED1 mRNA CTD PMID:15980968 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Mgat3 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase decreases expression ISO Carmustine results in decreased expression of MGAT3 mRNA CTD PMID:15980968 NCBI chr 7:121,394,541...121,436,935
Ensembl chr 7:121,408,829...121,435,022
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases alkylation
increases response to substance
multiple interactions
decreases expression
decreases response to substance
affects response to substance
decreases activity
ISO
EXP
Carmustine results in increased alkylation of MGMT protein
MGMT mutant form results in increased susceptibility to Carmustine
[MGMT protein co-treated with ABCB1 protein] results in decreased susceptibility to Carmustine; [MGMT protein mutant form co-treated with FECH protein] results in decreased susceptibility to [O(6)-benzylguanine co-treated with Carmustine]; [O(6)-benzyl-2'-deoxyguanosine results in decreased activity of MGMT protein] which results in increased susceptibility to Carmustine; [O(6)-benzyl-N-acetylguanosine results in decreased activity of MGMT protein] which results in increased susceptibility to Carmustine; [O(6)-benzylguanine co-treated with Carmustine] results in decreased activity of MGMT protein; [O(6)-benzylguanine results in decreased activity of MGMT protein] which results in increased susceptibility to Carmustine; [Tamoxifen results in increased degradation of MGMT protein] which results in increased susceptibility to Carmustine; MGMT protein mutant form results in decreased susceptibility to [Carmustine co-treated with O(6)-benzylguanine]; MGMT protein mutant form results in decreased susceptibility to [O(6)-benzylguanine co-treated with Carmustine]; MGMT protein results in decreased susceptibility to [Carmustine co-treated with O(6)-benzylguanine]; MGMT protein results in decreased susceptibility to [O(6)-benzylguanine co-treated with Carmustine]; O(6)-benzylguanine inhibits the reaction [MGMT protein mutant form results in decreased susceptibility to Carmustine]
Carmustine results in decreased expression of MGMT protein
MGMT protein results in decreased susceptibility to Carmustine
[O(6)-benzylguanine results in decreased activity of MGMT protein] which affects the susceptibility to Carmustine; MGMT protein mutant form results in decreased susceptibility to [Carmustine co-treated with O(6)-benzylguanine]; MGMT protein results in decreased susceptibility to [Carmustine co-treated with O(6)-benzylguanine]
MGMT protein affects the susceptibility to Carmustine
Carmustine results in decreased activity of MGMT protein
MGMT mRNA results in decreased susceptibility to Carmustine; MGMT protein mutant form results in decreased susceptibility to Carmustine; MGMT protein results in decreased susceptibility to Carmustine; MGMT protein results in decreased susceptibility to Carmustine analog; MGMT results in decreased susceptibility to Carmustine
MGMT gene modified form affects the susceptibility to Carmustine; MGMT promoter modified form affects the susceptibility to Carmustine; MGMT protein affects the susceptibility to Carmustine
CTD PMID:8823159, PMID:9918549, PMID:11792417, PMID:11945064, PMID:12036916, PMID:12394182, PMID:12479369, PMID:12684420, PMID:12950064, PMID:14506174, PMID:14617757, PMID:14670122, PMID:14707273, PMID:14742745, PMID:15104113, PMID:15284838, PMID:15319033, PMID:15814657, PMID:15833865, PMID:16033832, PMID:16039682, PMID:16126841, PMID:16278409, PMID:16365179, PMID:16405512, PMID:16432170, PMID:16899598, PMID:16927363, PMID:17597106, PMID:18430789, PMID:18492797, PMID:19415780, PMID:19637364, PMID:19844954, PMID:20450874, PMID:20556481, PMID:20654586, PMID:26208482 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 affects response to substance ISO MGST2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 2:140,708,396...140,727,381
Ensembl chr 2:140,708,397...140,727,281
JBrowse link
G Mlh1 mutL homolog 1 affects response to substance ISO MLH1 protein affects the susceptibility to Carmustine CTD PMID:18430789 NCBI chr 8:119,486,655...119,523,716
Ensembl chr 8:119,486,691...119,523,964
JBrowse link
G Mlph melanophilin affects response to substance ISO MLPH mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 9:98,072,965...98,108,429
Ensembl chr 9:98,073,038...98,108,433
JBrowse link
G Mpg N-methylpurine-DNA glycosylase decreases response to substance ISO MPG protein results in decreased susceptibility to Carmustine CTD PMID:16288039 NCBI chr10:15,661,768...15,667,995
Ensembl chr10:15,661,608...15,668,022
JBrowse link
G Mpst mercaptopyruvate sulfurtransferase affects response to substance ISO MPST mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 7:119,626,636...119,631,317
Ensembl chr 7:119,626,637...119,631,425
JBrowse link
G Msh2 mutS homolog 2 affects response to substance ISO MSH2 protein affects the susceptibility to Carmustine CTD PMID:18430789 NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
JBrowse link
G Msr1 macrophage scavenger receptor 1 decreases expression ISO Carmustine results in decreased expression of MSR1 mRNA CTD PMID:15980968 NCBI chr16:56,817,714...56,900,025
Ensembl chr16:56,813,791...56,900,052
JBrowse link
G Mt2A metallothionein 2A affects response to substance
multiple interactions
ISO
EXP
MT2A mRNA affects the susceptibility to Carmustine
MT2 protein inhibits the reaction [Carmustine results in decreased activity of GSR protein]; MT2 protein inhibits the reaction [Carmustine results in increased expression of TNF protein]
MT2 protein affects the susceptibility to Carmustine
CTD PMID:16365179, PMID:18528683 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mturn maturin, neural progenitor differentiation regulator homolog affects response to substance ISO MTURN mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 4:84,854,341...84,875,300
Ensembl chr 4:84,854,386...84,871,757
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming decreases expression ISO Carmustine results in decreased expression of MUC2 mRNA CTD PMID:15980968 NCBI chr 1:214,663,929...214,693,197 JBrowse link
G Mug1 murinoglobulin 1 decreases expression ISO Carmustine results in decreased expression of PZP mRNA CTD PMID:15980968 NCBI chr 4:154,676,382...154,729,288
Ensembl chr 4:154,391,647...154,729,310
JBrowse link
G Mvd mevalonate diphosphate decarboxylase decreases expression ISO Carmustine results in decreased expression of MVD mRNA CTD PMID:15980968 NCBI chr19:55,258,910...55,268,933
Ensembl chr19:55,258,905...55,268,951
JBrowse link
G Mybl2 MYB proto-oncogene like 2 increases expression EXP Carmustine results in increased expression of MYBL2 mRNA CTD PMID:16005536 NCBI chr 3:159,421,638...159,450,087
Ensembl chr 3:159,421,671...159,450,086
JBrowse link
G Mybph myosin binding protein H decreases expression ISO Carmustine results in decreased expression of MYBPH mRNA CTD PMID:15980968 NCBI chr13:51,034,228...51,041,903
Ensembl chr13:51,034,256...51,041,902
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor decreases expression ISO Carmustine results in decreased expression of MYD88 mRNA CTD PMID:15980968 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Myod1 myogenic differentiation 1 decreases expression ISO Carmustine results in decreased expression of MYOD1 mRNA CTD PMID:15980968 NCBI chr 1:102,396,538...102,399,248
Ensembl chr 1:102,396,538...102,399,248
JBrowse link
G Myog myogenin decreases expression ISO Carmustine results in decreased expression of MYOG mRNA CTD PMID:15980968 NCBI chr13:51,126,459...51,129,048
Ensembl chr13:51,126,459...51,129,048
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist affects response to substance ISO NBL1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:157,524,569...157,535,701
Ensembl chr 5:157,524,513...157,535,664
JBrowse link
G Ndufc1 NADH:ubiquinone oxidoreductase subunit C1 decreases expression ISO Carmustine results in decreased expression of NDUFC1 mRNA CTD PMID:15980968 NCBI chr 2:140,460,749...140,464,588
Ensembl chr 2:140,462,900...140,464,607
JBrowse link
G Nek6 NIMA-related kinase 6 increases expression EXP Carmustine results in increased expression of NEK6 mRNA CTD PMID:16005536 NCBI chr 3:22,811,927...22,888,598
Ensembl chr 3:22,811,927...22,888,598
JBrowse link
G Nes nestin increases expression
multiple interactions
EXP Carmustine results in increased expression of NES protein
Melatonin inhibits the reaction [Carmustine results in increased expression of NES protein]
CTD PMID:17572393 NCBI chr 2:187,343,109...187,352,972
Ensembl chr 2:187,344,056...187,352,969
JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 affects response to substance ISO NFAT5 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr19:38,446,059...38,533,735
Ensembl chr19:38,446,059...38,533,735
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects response to substance ISO [NFE2L2 affects the susceptibility to sulforafan] which affects the susceptibility to Carmustine CTD PMID:19303893 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfib nuclear factor I/B affects response to substance ISO NFIB mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:100,436,343...100,647,962
Ensembl chr 5:100,439,082...100,647,727
JBrowse link
G Nfix nuclear factor I X affects response to substance ISO NFIX mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr19:25,818,640...25,914,777
Ensembl chr19:25,821,780...25,914,696
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO
EXP
Carmustine results in increased activity of [NFKB1 protein binds to NFKB1 protein]; Carmustine results in increased activity of [NFKB1 protein binds to RELA protein]; NFKBIA gene mutant form inhibits the reaction [Carmustine results in increased activity of [NFKB1 protein binds to NFKB1 protein]]; NFKBIA gene mutant form inhibits the reaction [Carmustine results in increased activity of [NFKB1 protein binds to RELA protein]]
Carmustine inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein]; Carmustine inhibits the reaction [Lipopolysaccharides results in increased activity of [NFKB1 protein binds to RELA protein]]
[Carmustine co-treated with Oligodeoxyribonucleotides analog] results in increased activity of [NFKB1 protein binds to NFKB1 protein]; [Carmustine co-treated with Oligodeoxyribonucleotides analog] results in increased activity of [NFKB1 protein binds to RELA protein]; diphenyleneiodonium inhibits the reaction [[Carmustine co-treated with Oligodeoxyribonucleotides analog] results in increased activity of [NFKB1 protein binds to NFKB1 protein]]; diphenyleneiodonium inhibits the reaction [[Carmustine co-treated with Oligodeoxyribonucleotides analog] results in increased activity of [NFKB1 protein binds to RELA protein]]
CTD PMID:11970852, PMID:12433058, PMID:12477282, PMID:12675310 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases response to substance
ISO
EXP
NFKBIA gene mutant form inhibits the reaction [Carmustine results in increased activity of [NFKB1 protein binds to NFKB1 protein]]; NFKBIA gene mutant form inhibits the reaction [Carmustine results in increased activity of [NFKB1 protein binds to RELA protein]]
Carmustine inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; Carmustine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]
NFKBIA gene mutant form results in increased susceptibility to Carmustine; NFKBIA mRNA results in increased susceptibility to Carmustine
CTD PMID:11970852, PMID:12433058, PMID:12675310, PMID:16365179 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Ngef neuronal guanine nucleotide exchange factor decreases expression EXP Carmustine results in decreased expression of NGEF mRNA CTD PMID:16005536 NCBI chr 9:94,569,286...94,601,852
Ensembl chr 9:94,569,286...94,601,852
JBrowse link
G Ngf nerve growth factor affects activity EXP Carmustine affects the activity of NGF protein CTD PMID:15935206 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Nid2 nidogen 2 decreases expression EXP Carmustine results in decreased expression of NID2 mRNA CTD PMID:16005536 NCBI chr15:4,893,999...4,951,893
Ensembl chr15:4,894,213...4,951,917
JBrowse link
G Nin ninein affects response to substance ISO NIN mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 6:92,423,412...92,527,776
Ensembl chr 6:92,433,381...92,527,711
JBrowse link
G Nkd2 NKD inhibitor of WNT signaling pathway 2 affects response to substance ISO NKD2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:32,054,390...32,085,416
Ensembl chr 1:32,058,044...32,084,877
JBrowse link
G Nkx2-2 NK2 homeobox 2 decreases expression ISO Carmustine results in decreased expression of NKX2-2 mRNA CTD PMID:15980968 NCBI chr 3:141,408,460...141,419,083
Ensembl chr 3:141,408,798...141,411,170
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases response to substance
ISO
EXP
[NOS2 protein results in increased chemical synthesis of S-Nitrosoglutathione] which results in decreased susceptibility to Carmustine
NOS2 protein results in decreased susceptibility to Carmustine
[Carmustine co-treated with 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid] inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Nitrites]; [Carmustine co-treated with Buthionine Sulfoximine] inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Buthionine Sulfoximine promotes the reaction [Carmustine inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]]; Carmustine inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Carmustine]
CTD PMID:7532384, PMID:15110396, PMID:15965067 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npas1 neuronal PAS domain protein 1 decreases expression ISO Carmustine results in decreased expression of NPAS1 mRNA CTD PMID:15980968 NCBI chr 1:78,420,646...78,441,841
Ensembl chr 1:78,420,652...78,440,738
JBrowse link
G Npas2 neuronal PAS domain protein 2 affects response to substance ISO NPAS2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 9:45,901,262...46,081,880
Ensembl chr 9:45,901,741...46,081,880
JBrowse link
G Npl N-acetylneuraminate pyruvate lyase affects response to substance ISO NPL mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr13:70,938,073...70,981,179
Ensembl chr13:70,938,082...70,980,913
JBrowse link
G Npr1 natriuretic peptide receptor 1 decreases expression EXP Carmustine results in decreased expression of NPR1 mRNA CTD PMID:16005536 NCBI chr 2:189,840,403...189,857,032
Ensembl chr 2:189,840,403...189,856,090
JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 affects response to substance ISO NR2F1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 2:5,569,954...5,579,894
Ensembl chr 2:5,569,935...5,579,894
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 affects expression EXP Carmustine affects the expression of NR4A2 mRNA CTD PMID:19174181 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Nrtn neurturin decreases expression ISO Carmustine results in decreased expression of NRTN mRNA CTD PMID:15980968 NCBI chr 9:10,299,881...10,306,599
Ensembl chr 9:10,305,470...10,306,597
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases response to substance ISO OGG1 protein results in decreased susceptibility to Carmustine CTD PMID:11181913, PMID:11741815 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Omp olfactory marker protein decreases expression ISO Carmustine results in decreased expression of OMP mRNA CTD PMID:15980968 NCBI chr 1:163,097,159...163,097,709 JBrowse link
G Orm1 orosomucoid 1 increases expression EXP Carmustine results in increased expression of ORM1 mRNA CTD PMID:16005536 NCBI chr 5:79,179,668...79,182,820
Ensembl chr 5:79,179,417...79,182,820
JBrowse link
G P3h3 prolyl 3-hydroxylase 3 affects response to substance ISO P3H3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 4:157,359,331...157,375,186
Ensembl chr 4:157,359,332...157,372,861
JBrowse link
G Paep progestagen associated endometrial protein decreases expression ISO Carmustine results in decreased expression of PAEP mRNA CTD PMID:15980968 NCBI chr 3:2,935,396...2,938,883 JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO Disulfiram promotes the reaction [Carmustine results in increased cleavage of PARP1 protein] CTD PMID:24193513 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pax8 paired box 8 decreases expression ISO Carmustine results in decreased expression of PAX8 mRNA CTD PMID:15980968 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link
G Pbx2 PBX homeobox 2 decreases expression ISO Carmustine results in decreased expression of PBX2 mRNA CTD PMID:15980968 NCBI chr20:4,357,805...4,362,730
Ensembl chr20:4,357,733...4,362,682
JBrowse link
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 decreases expression ISO Carmustine results in decreased expression of PCBD1 mRNA CTD PMID:15980968 NCBI chr20:30,689,690...30,696,465
Ensembl chr20:30,690,810...30,696,476
JBrowse link
G Pcdhb2 protocadherin beta 2 affects response to substance ISO PCDHB2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr18:30,375,798...30,378,194
Ensembl chr18:30,375,798...30,378,194
JBrowse link
G Pcdhgc3 protocadherin gamma subfamily C, 3 decreases expression ISO Carmustine results in decreased expression of PCDHGC3 mRNA CTD PMID:15980968 NCBI chr18:30,954,552...30,971,113
Ensembl chr18:30,913,842...30,969,361
JBrowse link
G Pcolce procollagen C-endopeptidase enhancer decreases expression ISO Carmustine results in decreased expression of PCOLCE mRNA CTD PMID:15980968 NCBI chr12:22,153,995...22,160,311
Ensembl chr12:22,153,983...22,160,337
JBrowse link
G Pcyt1a phosphate cytidylyltransferase 1, choline, alpha decreases expression ISO Carmustine results in decreased expression of PCYT1A mRNA CTD PMID:15980968 NCBI chr11:71,547,865...71,592,037
Ensembl chr11:71,548,222...71,591,502
JBrowse link
G Pde5a phosphodiesterase 5A affects response to substance ISO PDE5A mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576
JBrowse link
G Pdgfb platelet derived growth factor subunit B increases expression ISO Carmustine results in increased expression of PDGFB protein CTD PMID:15286697 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 decreases expression ISO Carmustine results in decreased expression of PFKFB2 mRNA CTD PMID:15980968 NCBI chr13:47,413,453...47,440,682
Ensembl chr13:47,413,458...47,440,682
JBrowse link
G Pfkm phosphofructokinase, muscle decreases expression ISO Carmustine results in decreased expression of PFKM mRNA CTD PMID:15980968 NCBI chr 7:139,702,066...139,722,132
Ensembl chr 7:139,685,573...139,722,132
JBrowse link
G Pfn1 profilin 1 decreases expression ISO Carmustine results in decreased expression of PFN1 mRNA CTD PMID:15980968 NCBI chr10:57,273,003...57,275,708
Ensembl chr10:57,273,005...57,275,708
JBrowse link
G Pgm2 phosphoglucomutase 2 affects response to substance ISO PGM2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr14:45,829,440...45,863,883
Ensembl chr14:45,829,446...45,863,877
JBrowse link
G Phc2 polyhomeotic homolog 2 affects response to substance ISO PHC2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:146,832,552...146,931,444
Ensembl chr 5:146,882,756...146,931,444
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 affects response to substance ISO PHLDA1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 7:54,247,460...54,249,664
Ensembl chr 7:54,247,460...54,249,664
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 affects response to substance ISO PIK3C3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr18:22,964,121...23,047,896
Ensembl chr18:22,964,210...23,047,895
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta affects response to substance ISO PIK3CD mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:166,602,053...166,628,028
Ensembl chr 5:166,602,053...166,628,028
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 increases expression ISO Carmustine results in increased expression of PIK3R3 mRNA CTD PMID:15980968 NCBI chr 5:135,069,972...135,145,633
Ensembl chr 5:135,074,297...135,142,488
JBrowse link
G Pitpnc1 phosphatidylinositol transfer protein, cytoplasmic 1 affects response to substance ISO PITPNC1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr10:95,429,879...95,697,734 JBrowse link
G Pknox2 PBX/knotted 1 homeobox 2 decreases expression EXP Carmustine results in decreased expression of PKNOX2 mRNA CTD PMID:16005536 NCBI chr 8:39,361,698...39,551,700
Ensembl chr 8:39,361,218...39,551,700
JBrowse link
G Pkp2 plakophilin 2 increases expression EXP Carmustine results in increased expression of PKP2 mRNA CTD PMID:16005536 NCBI chr11:88,912,163...88,972,213 JBrowse link
G Pkp3 plakophilin 3 affects response to substance ISO PKP3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:213,884,795...213,897,783
Ensembl chr 1:213,886,775...213,897,783
JBrowse link
G Plekhg5 pleckstrin homology and RhoGEF domain containing G5 affects response to substance ISO PLEKHG5 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:169,244,778...169,288,310
Ensembl chr 5:169,244,778...169,288,309
JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 increases expression EXP Carmustine results in increased expression of PNPLA2 mRNA CTD PMID:16005536 NCBI chr 1:214,434,638...214,439,720
Ensembl chr 1:214,434,626...214,439,720
JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit affects response to substance ISO POLG2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr10:94,968,836...94,979,259
Ensembl chr10:94,968,836...94,979,259
JBrowse link
G Polh DNA polymerase eta multiple interactions ISO [Carmustine co-treated with MDM4 protein] results in increased expression of POLH protein CTD PMID:20472715 NCBI chr 9:17,163,354...17,198,006
Ensembl chr 9:17,163,354...17,197,132
JBrowse link
G Polr2e RNA polymerase II, I and III subunit E decreases expression ISO Carmustine results in decreased expression of POLR2E mRNA CTD PMID:15980968 NCBI chr 7:12,532,785...12,536,797
Ensembl chr 7:12,532,895...12,536,791
JBrowse link
G Popdc3 popeye domain containing 3 affects response to substance ISO POPDC3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr20:50,394,617...50,422,551
Ensembl chr20:50,394,650...50,422,560
JBrowse link
G Ppm1g protein phosphatase, Mg2+/Mn2+ dependent, 1G decreases expression ISO Carmustine results in decreased expression of PPM1G mRNA CTD PMID:15980968 NCBI chr 6:26,517,840...26,537,292
Ensembl chr 6:26,517,840...26,537,290
JBrowse link
G Prc1 protein regulator of cytokinesis 1 decreases expression ISO Carmustine results in decreased expression of PRC1 mRNA CTD PMID:17374387 NCBI chr 1:142,087,181...142,108,746
Ensembl chr 1:142,087,208...142,108,746
JBrowse link
G Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 affects response to substance ISO PREX1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 3:163,329,580...163,477,822
Ensembl chr 3:163,329,975...163,477,715
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 affects response to substance ISO PRKAA2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:124,568,845...124,642,569
Ensembl chr 5:124,574,079...124,642,569
JBrowse link
G Prl prolactin decreases expression ISO Carmustine results in decreased expression of PRL mRNA CTD PMID:15980968 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Prm2 protamine 2 decreases expression ISO Carmustine results in decreased expression of PRM2 mRNA CTD PMID:15980968 NCBI chr10:4,950,484...4,950,920
Ensembl chr10:4,950,484...4,950,920
JBrowse link
G Prph peripherin decreases expression EXP Carmustine results in decreased expression of PRPH mRNA CTD PMID:16005536 NCBI chr 7:140,742,406...140,746,197
Ensembl chr 7:140,742,418...140,746,197
JBrowse link
G Prrx2 paired related homeobox 2 affects response to substance ISO PRRX2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 3:9,681,871...9,718,051
Ensembl chr 3:9,681,871...9,718,051
JBrowse link
G Prss12 serine protease 12 affects response to substance ISO PRSS12 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 2:227,657,983...227,717,884
Ensembl chr 2:227,657,983...227,717,884
JBrowse link
G Pth2r parathyroid hormone 2 receptor decreases expression EXP Carmustine results in decreased expression of PTH2R mRNA CTD PMID:16005536 NCBI chr 9:72,052,966...72,158,343
Ensembl chr 9:72,052,966...72,157,773
JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 decreases expression ISO Carmustine results in decreased expression of PTPN3 mRNA CTD PMID:15980968 NCBI chr 5:74,248,996...74,368,167
Ensembl chr 5:74,248,996...74,368,186
JBrowse link
G Qpct glutaminyl-peptide cyclotransferase affects response to substance ISO QPCT mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 6:1,657,110...1,689,575
Ensembl chr 6:1,657,331...1,689,559
JBrowse link
G Rab27b RAB27B, member RAS oncogene family affects response to substance ISO RAB27B mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr18:68,486,006...68,644,595
Ensembl chr18:68,488,942...68,551,558
JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein decreases expression ISO Carmustine results in decreased expression of RAD23A mRNA CTD PMID:15980968 NCBI chr19:25,949,488...25,956,677
Ensembl chr19:25,949,490...25,955,391
JBrowse link
G Rad51 RAD51 recombinase decreases expression ISO Carmustine results in decreased expression of RAD51 mRNA CTD PMID:15980968 NCBI chr 3:110,918,240...110,942,920
Ensembl chr 3:110,918,243...110,942,917
JBrowse link
G Rad9a RAD9 checkpoint clamp component A decreases expression ISO Carmustine results in decreased expression of RAD9A mRNA CTD PMID:15980968 NCBI chr 1:219,443,347...219,450,574
Ensembl chr 1:219,444,092...219,450,451
JBrowse link
G Rbm19 RNA binding motif protein 19 affects response to substance ISO RBM19 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr12:41,907,978...41,993,969
Ensembl chr12:41,907,740...41,993,957
JBrowse link
G Rcn1 reticulocalbin 1 decreases expression ISO Carmustine results in decreased expression of RCN1 mRNA CTD PMID:15980968 NCBI chr 3:95,404,863...95,419,110
Ensembl chr 3:95,406,284...95,418,679
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions EXP Carmustine inhibits the reaction [Lipopolysaccharides affects the localization of REL protein] CTD PMID:11970852, PMID:12433058 NCBI chr14:108,490,794...108,517,582
Ensembl chr14:108,491,069...108,509,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP
Carmustine results in increased activity of [NFKB1 protein binds to RELA protein]; NFKBIA gene mutant form inhibits the reaction [Carmustine results in increased activity of [NFKB1 protein binds to RELA protein]]
Carmustine inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; Carmustine inhibits the reaction [Lipopolysaccharides results in increased activity of [NFKB1 protein binds to RELA protein]]
[Carmustine co-treated with Oligodeoxyribonucleotides analog] results in increased activity of [NFKB1 protein binds to RELA protein]; diphenyleneiodonium inhibits the reaction [[Carmustine co-treated with Oligodeoxyribonucleotides analog] results in increased activity of [NFKB1 protein binds to RELA protein]]
CTD PMID:11970852, PMID:12433058, PMID:12477282, PMID:12675310 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit multiple interactions EXP Carmustine inhibits the reaction [Lipopolysaccharides affects the localization of RELB protein] CTD PMID:11970852, PMID:12433058 NCBI chr 1:80,517,081...80,545,019
Ensembl chr 1:80,517,411...80,544,825
JBrowse link
G Rfc3 replication factor C subunit 3 decreases expression EXP Carmustine results in decreased expression of RFC3 mRNA CTD PMID:16005536 NCBI chr12:1,460,581...1,471,344
Ensembl chr12:1,460,538...1,471,357
JBrowse link
G Rgcc regulator of cell cycle affects response to substance ISO RGCC mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr15:61,551,861...61,564,695
Ensembl chr15:61,551,861...61,564,695
JBrowse link
G Rgp1 RGP1 homolog, RAB6A GEF complex partner 1 affects response to substance ISO RGP1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:59,080,290...59,088,777
Ensembl chr 5:59,080,765...59,088,523
JBrowse link
G Rgr retinal G protein coupled receptor decreases expression ISO Carmustine results in decreased expression of RGR mRNA CTD PMID:15980968 NCBI chr16:14,286,323...14,300,972
Ensembl chr16:14,286,323...14,300,951
JBrowse link
G Rhobtb3 Rho-related BTB domain containing 3 affects response to substance ISO RHOBTB3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 2:2,627,655...2,683,305
Ensembl chr 2:2,627,393...2,683,116
JBrowse link
G Rit2 Ras-like without CAAX 2 decreases expression ISO Carmustine results in decreased expression of RIT2 mRNA CTD PMID:15980968 NCBI chr18:23,700,012...24,057,917
Ensembl chr18:23,700,013...24,057,917
JBrowse link
G Rnase4 ribonuclease A family member 4 increases expression ISO Carmustine results in increased expression of RNASE4 mRNA CTD PMID:15980968 NCBI chr15:28,018,040...28,035,395
Ensembl chr15:28,018,040...28,035,389
Ensembl chr15:28,018,040...28,035,389
JBrowse link
G Rorb RAR-related orphan receptor B affects expression EXP Carmustine affects the expression of RORB mRNA CTD PMID:19174181 NCBI chr 1:234,252,757...234,442,597
Ensembl chr 1:234,252,757...234,435,839
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 affects response to substance ISO SAT1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Scamp5 secretory carrier membrane protein 5 affects response to substance ISO SCAMP5 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 8:62,221,820...62,266,269
Ensembl chr 8:62,220,892...62,248,017
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 increases expression EXP Carmustine results in increased expression of SCN1B mRNA CTD PMID:16005536 NCBI chr 1:89,550,738...89,560,469
Ensembl chr 1:89,550,738...89,560,719
JBrowse link
G Scn8a sodium voltage-gated channel alpha subunit 8 affects response to substance ISO SCN8A mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 7:142,575,629...142,683,659
Ensembl chr 7:142,575,672...142,684,114
JBrowse link
G Sdc1 syndecan 1 affects response to substance ISO SDC1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 6:33,885,576...33,908,038
Ensembl chr 6:33,885,495...33,908,016
JBrowse link
G Sema3a semaphorin 3A affects response to substance ISO SEMA3A mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 4:18,170,375...18,545,190
Ensembl chr 4:18,178,656...18,396,035
JBrowse link
G Septin4 septin 4 decreases expression EXP Carmustine results in decreased expression of SEPTIN4 mRNA CTD PMID:16005536 NCBI chr10:74,860,068...74,884,196
Ensembl chr10:74,861,714...74,884,196
JBrowse link
G Septin5 septin 5 decreases expression ISO Carmustine results in decreased expression of SEPTIN5 mRNA CTD PMID:15980968 NCBI chr11:86,516,377...86,522,169
Ensembl chr11:86,512,797...86,522,168
JBrowse link
G Serpinb1a serpin family B member 1A affects response to substance ISO SERPINB1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr17:32,903,089...32,911,498
Ensembl chr17:32,904,119...32,911,495
JBrowse link
G Sf1 splicing factor 1 affects response to substance ISO SF1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:221,735,512...221,749,216
Ensembl chr 1:221,735,517...221,749,086
JBrowse link
G Sfpq splicing factor proline and glutamine rich decreases expression ISO Carmustine results in decreased expression of SFPQ mRNA CTD PMID:15980968 NCBI chr 5:145,079,803...145,088,517
Ensembl chr 5:145,079,803...145,088,498
JBrowse link
G Sgca sarcoglycan, alpha decreases expression ISO Carmustine results in decreased expression of SGCA mRNA CTD PMID:15980968 NCBI chr10:82,770,905...82,785,142
Ensembl chr10:82,770,905...82,785,142
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 decreases expression ISO Carmustine results in decreased expression of SHMT2 mRNA CTD PMID:15980968 NCBI chr 7:70,824,718...70,829,822
Ensembl chr 7:70,824,715...70,829,815
JBrowse link
G Slc10a1 solute carrier family 10 member 1 increases expression ISO Carmustine results in increased expression of SLC10A1 mRNA CTD PMID:15980968 NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
JBrowse link
G Slc12a1 solute carrier family 12 member 1 decreases expression EXP Carmustine results in decreased expression of SLC12A1 mRNA CTD PMID:17727784 NCBI chr 3:117,421,531...117,498,372
Ensembl chr 3:117,421,604...117,498,367
JBrowse link
G Slc12a2 solute carrier family 12 member 2 increases expression EXP Carmustine results in increased expression of SLC12A2 mRNA CTD PMID:17727784 NCBI chr18:52,917,124...52,985,281
Ensembl chr18:52,917,124...52,985,261
JBrowse link
G Slc14a1 solute carrier family 14 member 1 (Kidd blood group) affects response to substance ISO SLC14A1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr18:74,461,064...74,504,475
Ensembl chr18:74,461,055...74,485,139
JBrowse link
G Slc15a2 solute carrier family 15 member 2 affects response to substance ISO SLC15A2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr11:66,932,664...66,961,708
Ensembl chr11:66,932,614...66,961,713
JBrowse link
G Slc16a2 solute carrier family 16 member 2 increases expression ISO Carmustine results in increased expression of SLC16A2 mRNA CTD PMID:15980968 NCBI chr  X:74,578,600...74,706,068
Ensembl chr  X:74,577,131...74,706,214
JBrowse link
G Slc19a2 solute carrier family 19 member 2 decreases expression EXP Carmustine results in decreased expression of SLC19A2 mRNA CTD PMID:16005536 NCBI chr13:82,552,586...82,566,586
Ensembl chr13:82,552,550...82,566,586
JBrowse link
G Slc22a5 solute carrier family 22 member 5 affects response to substance ISO SLC22A5 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr10:39,201,101...39,228,090
Ensembl chr10:39,201,107...39,323,853
JBrowse link
G Slc30a3 solute carrier family 30 member 3 decreases expression ISO Carmustine results in decreased expression of SLC30A3 mRNA CTD PMID:15980968 NCBI chr 6:26,629,752...26,650,106
Ensembl chr 6:26,642,783...26,650,105
JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression EXP Carmustine results in increased expression of SLC3A2 mRNA CTD PMID:16005536 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092
JBrowse link
G Slc6a2 solute carrier family 6 member 2 increases expression ISO Carmustine results in increased expression of SLC6A2 mRNA CTD PMID:15980968 NCBI chr19:15,391,682...15,431,274
Ensembl chr19:15,391,581...15,431,274
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 decreases expression ISO Carmustine results in decreased expression of SLCO1A2 mRNA CTD PMID:15980968 NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor affects response to substance ISO SLPI mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link
G Smarcd1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 increases expression ISO Carmustine results in increased expression of SMARCD1 mRNA CTD PMID:15980968 NCBI chr 7:141,355,623...141,366,725
Ensembl chr 7:141,355,994...141,366,732
JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 increases expression ISO Carmustine results in increased expression of SMPD2 mRNA CTD PMID:15980968 NCBI chr20:46,212,070...46,215,183
Ensembl chr20:46,211,892...46,215,120
JBrowse link
G Snapc1 small nuclear RNA activating complex, polypeptide 1 increases expression ISO Carmustine results in increased expression of SNAPC1 mRNA CTD PMID:15980968 NCBI chr 6:96,871,675...96,893,422
Ensembl chr 6:96,871,625...96,893,444
JBrowse link
G Snapc3 small nuclear RNA activating complex, polypeptide 3 increases expression ISO Carmustine results in increased expression of SNAPC3 mRNA CTD PMID:15980968 NCBI chr 5:101,526,591...101,554,015
Ensembl chr 5:101,526,551...101,553,489
JBrowse link
G Sncg synuclein, gamma increases expression ISO Carmustine results in increased expression of SNCG mRNA CTD PMID:15980968 NCBI chr16:10,722,110...10,726,648
Ensembl chr16:10,722,106...10,726,707
JBrowse link
G Snrpb2 small nuclear ribonucleoprotein polypeptide B2 increases expression ISO Carmustine results in increased expression of SNRPB2 mRNA CTD PMID:15980968 NCBI chr 3:137,138,082...137,147,575
Ensembl chr 3:137,137,980...137,147,575
JBrowse link
G Socs1 suppressor of cytokine signaling 1 decreases expression ISO Carmustine results in decreased expression of SOCS1 mRNA CTD PMID:17374387 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461
JBrowse link
G Sod1 superoxide dismutase 1 decreases activity ISO Carmustine results in decreased activity of SOD1 protein CTD PMID:19856331 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 affects response to substance
increases response to substance
multiple interactions
decreases activity
ISO SOD2 mRNA affects the susceptibility to Carmustine
SOD2 protein results in increased susceptibility to Carmustine
Pyruvates inhibits the reaction [SOD2 protein results in increased susceptibility to Carmustine]
Carmustine results in decreased activity of SOD2 protein
CTD PMID:8877099, PMID:16365179, PMID:19856331 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sorbs2 sorbin and SH3 domain containing 2 decreases expression ISO Carmustine results in decreased expression of SORBS2 mRNA CTD PMID:15980968 NCBI chr16:49,626,205...49,820,223
Ensembl chr16:49,626,205...49,820,235
JBrowse link
G Sox9 SRY-box transcription factor 9 affects response to substance ISO SOX9 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Sparc secreted protein acidic and cysteine rich affects response to substance ISO SPARC mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
G Speg striated muscle enriched protein kinase decreases expression ISO Carmustine results in decreased expression of SPEG mRNA CTD PMID:15980968 NCBI chr 9:82,571,333...82,628,684
Ensembl chr 9:82,571,269...82,628,709
JBrowse link
G Spen spen family transcriptional repressor affects response to substance ISO SPEN mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:160,015,573...160,070,915
Ensembl chr 5:160,015,454...160,070,965
JBrowse link
G Sqle squalene epoxidase affects response to substance ISO SQLE mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 7:99,609,929...99,624,803
Ensembl chr 7:99,609,191...99,624,732
JBrowse link
G Srp14 signal recognition particle 14 decreases expression ISO Carmustine results in decreased expression of SRP14 mRNA CTD PMID:15980968 NCBI chr 3:110,245,936...110,249,627
Ensembl chr 3:110,245,936...110,249,627
JBrowse link
G Sry sex determining region Y decreases expression ISO Carmustine results in decreased expression of SRY mRNA CTD PMID:15980968 NCBI chr  Y:327,176...327,685
Ensembl chr  Y:327,166...329,299
JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 affects response to substance ISO ST3GAL1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 7:107,895,045...107,963,158
Ensembl chr 7:107,895,045...107,963,142
JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 increases expression ISO Carmustine results in increased expression of ST6GAL1 mRNA CTD PMID:15980968 NCBI chr11:80,927,601...80,981,424
Ensembl chr11:80,927,601...80,981,422
JBrowse link
G St8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 increases expression ISO Carmustine results in increased expression of ST8SIA1 mRNA CTD PMID:15980968 NCBI chr 4:177,065,266...177,195,942
Ensembl chr 4:177,065,168...177,196,180
JBrowse link
G Stam signal transducing adaptor molecule decreases expression ISO Carmustine results in decreased expression of STAM mRNA CTD PMID:15980968 NCBI chr17:81,209,795...81,256,111
Ensembl chr17:81,209,867...81,255,808
JBrowse link
G Stc1 stanniocalcin 1 affects response to substance ISO STC1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr15:50,891,137...50,901,791
Ensembl chr15:50,891,127...50,903,162
JBrowse link
G Stmn1 stathmin 1 affects response to substance ISO STMN1 mRNA affects the susceptibility to Carmustine CTD PMID:17440165 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806
JBrowse link
G Sts steroid sulfatase increases expression ISO Carmustine results in increased expression of STS mRNA CTD PMID:15980968 NCBI chr  X:45,420,418...45,428,748
Ensembl chr  X:45,420,596...45,428,750
JBrowse link
G Stx1b syntaxin 1B decreases expression ISO Carmustine results in decreased expression of STX1B mRNA CTD PMID:15980968 NCBI chr 1:199,251,842...199,270,465
Ensembl chr 1:199,251,844...199,270,627
JBrowse link
G Stxbp2 syntaxin binding protein 2 decreases expression ISO Carmustine results in decreased expression of STXBP2 mRNA CTD PMID:15980968 NCBI chr12:2,180,101...2,191,863
Ensembl chr12:2,180,150...2,191,175
JBrowse link
G Stxbp6 syntaxin binding protein 6 affects response to substance ISO STXBP6 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 6:65,086,483...65,319,527
Ensembl chr 6:65,089,318...65,319,527
JBrowse link
G Synpo2 synaptopodin 2 affects response to substance ISO SYNPO2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 2:227,255,243...227,411,924
Ensembl chr 2:227,255,902...227,411,964
JBrowse link
G Syp synaptophysin multiple interactions
decreases expression
EXP Melatonin inhibits the reaction [Carmustine results in decreased expression of SYP protein] CTD PMID:17572393 NCBI chr  X:15,694,699...15,709,244
Ensembl chr  X:15,695,566...15,707,436
JBrowse link
G Tac1 tachykinin, precursor 1 decreases expression ISO Carmustine results in decreased expression of TAC1 mRNA CTD PMID:15980968 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tagln transgelin affects response to substance ISO TAGLN mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 8:50,222,895...50,228,369
Ensembl chr 8:50,222,896...50,231,357
JBrowse link
G Tbx3 T-box transcription factor 3 affects response to substance ISO TBX3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr12:42,479,518...42,494,588
Ensembl chr12:42,480,560...42,492,526
JBrowse link
G Tcf21 transcription factor 21 decreases expression ISO Carmustine results in decreased expression of TCF21 mRNA CTD PMID:15980968 NCBI chr 1:23,906,717...23,909,576
Ensembl chr 1:23,906,717...23,909,566
JBrowse link
G Tcim transcriptional and immune response regulator increases response to substance ISO TCIM mRNA results in increased susceptibility to Carmustine CTD PMID:16365179 NCBI chr16:72,401,526...72,403,180
Ensembl chr16:72,401,887...72,403,179
JBrowse link
G Tdrp testis development related protein affects response to substance ISO TDRP mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr16:80,729,342...80,755,397
Ensembl chr16:80,729,400...80,755,415
JBrowse link
G Tert telomerase reverse transcriptase decreases response to substance ISO TERT protein mutant form results in decreased susceptibility to Carmustine CTD PMID:12488552 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tfap2c transcription factor AP-2 gamma affects response to substance ISO TFAP2C mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 3:170,550,314...170,558,197
Ensembl chr 3:170,550,314...170,558,194
JBrowse link
G Tfdp1 transcription factor Dp-1 affects response to substance ISO TFDP1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr16:81,088,642...81,127,244
Ensembl chr16:81,089,292...81,127,257
JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 affects response to substance ISO TFPI2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 4:28,947,951...28,953,261
Ensembl chr 4:28,947,965...28,953,067
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases expression
EXP Melatonin inhibits the reaction [Carmustine results in decreased expression of TGFB1 protein] CTD PMID:17572393 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Th tyrosine hydroxylase increases activity
increases expression
EXP Carmustine results in increased activity of TH protein
Carmustine results in increased expression of TH mRNA; Carmustine results in increased expression of TH protein
CTD PMID:14670008 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Thbd thrombomodulin affects response to substance ISO THBD mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Tle3 TLE family member 3, transcriptional corepressor decreases expression ISO Carmustine results in decreased expression of TLE3 mRNA CTD PMID:15980968 NCBI chr 8:66,296,509...66,342,186
Ensembl chr 8:66,296,883...66,342,176
JBrowse link
G Tmem158 transmembrane protein 158 affects response to substance ISO TMEM158 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 8:132,344,710...132,345,708
Ensembl chr 8:132,344,710...132,345,708
JBrowse link
G Tmem19 transmembrane protein 19 affects response to substance ISO TMEM19 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 7:58,316,583...58,343,761
Ensembl chr 7:58,316,514...58,343,145
JBrowse link
G Tmprss15 transmembrane serine protease 15 affects response to substance ISO TMPRSS15 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr11:17,561,591...17,684,903
Ensembl chr11:17,561,596...17,684,903
JBrowse link
G Tnc tenascin C affects response to substance ISO TNC mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP
ISO
[Carmustine co-treated with 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid] inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Nitrites]; [Carmustine co-treated with Buthionine Sulfoximine] inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Buthionine Sulfoximine promotes the reaction [Carmustine inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]]; Carmustine inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; Carmustine promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; MT2 protein inhibits the reaction [Carmustine results in increased expression of TNF protein]; Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Carmustine]; Zinc Sulfate inhibits the reaction [Carmustine results in increased expression of TNF protein]
Carmustine promotes the reaction [Oligodeoxyribonucleotides analog results in increased secretion of TNF protein]
CTD PMID:7532384, PMID:11970852, PMID:12433058, PMID:12477282, PMID:18528683, PMID:20046642 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases response to substance ISO TNFAIP3 mRNA results in increased susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:14,401,103...14,416,369
Ensembl chr 1:14,402,913...14,412,807
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B decreases expression ISO Carmustine results in decreased expression of TNFRSF11B mRNA CTD PMID:15980968 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
G Tnfrsf19 TNF receptor superfamily member 19 affects response to substance ISO TNFRSF19 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr15:41,249,820...41,316,203
Ensembl chr15:41,246,308...41,338,284
JBrowse link
G Tnfsf10 TNF superfamily member 10 affects response to substance ISO TNFSF10 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
increases response to substance
decreases response to substance
affects response to substance
ISO [Carmustine co-treated with O(6)-benzylguanine] results in increased expression of TP53 protein; MDM4 protein promotes the reaction [Carmustine results in increased expression of TP53 protein]
TP53 results in increased susceptibility to Carmustine
TP53 protein results in decreased susceptibility to Carmustine
TP53 protein modified form affects the susceptibility to Carmustine
CTD PMID:10455409, PMID:11861384, PMID:15735757, PMID:16193384, PMID:18632648, PMID:20472715 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpd52l1 TPD52 like 1 affects response to substance ISO TPD52L1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:28,454,949...28,578,736
Ensembl chr 1:28,454,966...28,576,553
JBrowse link
G Traf1 TNF receptor-associated factor 1 decreases expression ISO Carmustine results in decreased expression of TRAF1 mRNA CTD PMID:15980968 NCBI chr 3:14,003,340...14,022,955
Ensembl chr 3:14,003,340...14,022,672
JBrowse link
G Trex1 three prime repair exonuclease 1 increases expression ISO Carmustine results in increased expression of TREX1 mRNA CTD PMID:23578789 NCBI chr 8:117,796,127...117,797,427
Ensembl chr 8:117,796,128...117,797,427
JBrowse link
G Trim50 tripartite motif-containing 50 affects response to substance ISO TRIM50 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr12:24,348,426...24,365,467
Ensembl chr12:24,348,321...24,365,324
JBrowse link
G Tspan4 tetraspanin 4 decreases expression ISO Carmustine results in decreased expression of TSPAN4 mRNA CTD PMID:15980968 NCBI chr 1:214,454,090...214,473,789
Ensembl chr 1:214,454,090...214,473,741
JBrowse link
G Tubb5 tubulin, beta 5 class I increases expression ISO Carmustine results in increased expression of TUBB mRNA CTD PMID:15980968 NCBI chr20:3,422,448...3,426,420
Ensembl chr20:3,422,461...3,426,371
JBrowse link
G Tubg1 tubulin, gamma 1 decreases expression ISO Carmustine results in decreased expression of TUBG1 mRNA CTD PMID:15980968 NCBI chr10:89,030,865...89,037,455
Ensembl chr10:89,030,865...89,037,455
JBrowse link
G Tufm Tu translation elongation factor, mitochondrial affects response to substance ISO TUFM mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:197,903,582...197,907,189
Ensembl chr 1:197,903,582...197,907,189
JBrowse link
G Tulp3 TUB like protein 3 affects response to substance ISO TULP3 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 4:161,636,084...161,677,807
Ensembl chr 4:161,637,892...161,658,519
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions
decreases activity
EXP [Carmustine co-treated with Buthionine Sulfoximine] results in decreased activity of TXNRD1 protein
Carmustine results in decreased activity of TXNRD1 protein
CTD PMID:16085187, PMID:16288907 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Ugt8 UDP glycosyltransferase 8 increases expression ISO Carmustine results in increased expression of UGT8 mRNA CTD PMID:15980968 NCBI chr 2:229,644,373...229,718,678
Ensembl chr 2:229,644,382...229,718,659
JBrowse link
G Upf1 UPF1, RNA helicase and ATPase decreases expression ISO Carmustine results in decreased expression of UPF1 mRNA CTD PMID:15980968 NCBI chr16:20,824,888...20,845,632
Ensembl chr16:20,824,864...20,845,243
JBrowse link
G Vamp4 vesicle-associated membrane protein 4 affects response to substance ISO VAMP4 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr13:80,460,699...80,483,597
Ensembl chr13:80,460,694...80,483,600
JBrowse link
G Vat1l vesicle amine transport 1-like affects response to substance ISO VAT1L mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr19:46,525,895...46,693,838
Ensembl chr19:46,525,919...46,693,838
JBrowse link
G Vgf VGF nerve growth factor inducible decreases expression ISO Carmustine results in decreased expression of VGF mRNA CTD PMID:15980968 NCBI chr12:22,677,302...22,680,630
Ensembl chr12:22,677,607...22,680,630
JBrowse link
G Vldlr very low density lipoprotein receptor affects response to substance ISO VLDLR mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:245,236,819...245,273,688
Ensembl chr 1:245,237,736...245,269,205
JBrowse link
G Wasf2 WASP family member 2 affects response to substance ISO WASF2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 5:151,319,382...151,385,051
Ensembl chr 5:151,343,493...151,381,238
JBrowse link
G Wfdc1 WAP four-disulfide core domain 1 affects response to substance ISO WFDC1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr19:52,313,771...52,332,721
Ensembl chr19:52,313,795...52,332,697
JBrowse link
G Wipf1 WAS/WASL interacting protein family, member 1 decreases expression ISO Carmustine results in decreased expression of WIPF1 mRNA CTD PMID:15980968 NCBI chr 3:60,150,001...60,207,125
Ensembl chr 3:60,150,021...60,166,013
JBrowse link
G Wnt5a Wnt family member 5A affects response to substance ISO WNT5A mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
G Wt1 WT1 transcription factor decreases response to substance ISO WT1 results in decreased susceptibility to Carmustine CTD PMID:20820871 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta decreases expression ISO Carmustine results in decreased expression of YWHAH mRNA CTD PMID:15980968 NCBI chr14:83,053,041...83,062,424
Ensembl chr14:83,053,041...83,062,424
JBrowse link
G Zbtb17 zinc finger and BTB domain containing 17 decreases expression ISO Carmustine results in decreased expression of ZBTB17 mRNA CTD PMID:15980968 NCBI chr 5:159,993,799...160,014,899
Ensembl chr 5:159,993,799...160,014,895
JBrowse link
G Zc3h13 zinc finger CCCH type containing 13 affects response to substance ISO ZC3H13 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr15:57,340,522...57,405,287
Ensembl chr15:57,340,579...57,405,287
JBrowse link
G Zfp112 zinc finger protein 112 affects response to substance ISO ZNF112 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr 1:80,944,118...80,959,072
Ensembl chr 1:80,953,275...80,958,908
JBrowse link
G Zfp189 zinc finger protein 189 increases expression EXP Carmustine results in increased expression of ZNF189 mRNA CTD PMID:16005536 NCBI chr 5:64,789,432...64,801,079
Ensembl chr 5:64,789,456...64,800,810
JBrowse link
G Zfp655 zinc finger protein 655 affects response to substance ISO ZNF655 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 NCBI chr12:11,122,779...11,146,182
Ensembl chr12:11,127,754...11,144,754
JBrowse link
G Zyx zyxin decreases expression ISO Carmustine results in decreased expression of ZYX mRNA CTD PMID:15980968 NCBI chr 4:71,740,188...71,749,386
Ensembl chr 4:71,740,532...71,749,386
JBrowse link
fotemustine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO fotemustine results in increased expression of CDKN1A mRNA CTD PMID:25125662 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO fotemustine results in increased expression of FAS mRNA CTD PMID:25125662 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO FOS mutant form inhibits the reaction [fotemustine results in increased expression of TREX1 mRNA]
fotemustine results in increased expression of FOS mRNA; fotemustine results in increased expression of FOS protein
CTD PMID:23578789 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO fotemustine results in increased expression of GADD45A mRNA CTD PMID:25125662 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G H2ax H2A.X variant histone increases expression ISO fotemustine results in increased expression of H2AX protein modified form CTD PMID:25125662 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO fotemustine promotes the reaction [JUN protein binds to TREX1 promoter]; JUN mutant form inhibits the reaction [fotemustine results in increased expression of TREX1 mRNA]
fotemustine results in increased expression of JUN mRNA; fotemustine results in increased expression of JUN protein
CTD PMID:23578789 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases response to substance ISO MGMT protein results in decreased susceptibility to fotemustine CTD PMID:12970393, PMID:16039682, PMID:20556481 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Polh DNA polymerase eta multiple interactions
decreases response to substance
increases expression
ISO Dactinomycin inhibits the reaction [fotemustine results in increased expression of POLH mRNA]; fotemustine promotes the reaction [TP53 protein binds to POLH promoter]; pifithrin inhibits the reaction [fotemustine results in increased expression of POLH mRNA]; pifithrin inhibits the reaction [fotemustine results in increased expression of POLH protein]
POLH protein results in decreased susceptibility to fotemustine
fotemustine results in increased expression of POLH mRNA; fotemustine results in increased expression of POLH protein
CTD PMID:25125662 NCBI chr 9:17,163,354...17,198,006
Ensembl chr 9:17,163,354...17,197,132
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
ISO fotemustine promotes the reaction [TP53 protein binds to POLH promoter]
fotemustine results in increased expression of TP53 protein; fotemustine results in increased expression of TP53 protein modified form
CTD PMID:25125662 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trex1 three prime repair exonuclease 1 multiple interactions
affects response to substance
increases expression
ISO FOS mutant form inhibits the reaction [fotemustine results in increased expression of TREX1 mRNA]; fotemustine promotes the reaction [JUN protein binds to TREX1 promoter]; JUN mutant form inhibits the reaction [fotemustine results in increased expression of TREX1 mRNA]
TREX1 affects the susceptibility to fotemustine
fotemustine results in increased expression of TREX1 mRNA; fotemustine results in increased expression of TREX1 protein
CTD PMID:23578789 NCBI chr 8:117,796,127...117,797,427
Ensembl chr 8:117,796,128...117,797,427
JBrowse link
lomustine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Lomustine results in increased expression of ABCB1 protein CTD PMID:15239124 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Lomustine results in increased expression of CDKN1A mRNA; Lomustine results in increased expression of CDKN1A protein CTD PMID:24211769, PMID:27358234 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Lomustine results in increased expression of DDIT3 protein CTD PMID:27358234 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha multiple interactions ISO INA affects the susceptibility to [Procarbazine co-treated with Lomustine co-treated with Vincristine] CTD PMID:21246521 NCBI chr 1:266,782,835...266,794,389
Ensembl chr 1:266,781,617...266,794,431
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase multiple interactions
decreases response to substance
ISO MGMT protein affects the susceptibility to [Procarbazine co-treated with Lomustine co-treated with Vincristine]
MGMT mRNA results in decreased susceptibility to Lomustine
CTD PMID:15448748, PMID:16033832 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Polh DNA polymerase eta increases expression
multiple interactions
decreases response to substance
ISO Lomustine results in increased expression of POLH mRNA; Lomustine results in increased expression of POLH protein
pifithrin inhibits the reaction [Lomustine results in increased expression of POLH protein]
POLH protein results in decreased susceptibility to Lomustine
CTD PMID:25125662 NCBI chr 9:17,163,354...17,198,006
Ensembl chr 9:17,163,354...17,197,132
JBrowse link
G Socs1 suppressor of cytokine signaling 1 decreases expression ISO Lomustine results in decreased expression of SOCS1 mRNA CTD PMID:17374387 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Lomustine results in increased expression of SRXN1 protein CTD PMID:27358234 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Stmn1 stathmin 1 affects response to substance ISO STMN1 mRNA affects the susceptibility to Lomustine CTD PMID:17440165 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806
JBrowse link
N-ethyl-N-nitrosourea term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of AARS mRNA CTD PMID:27776689 NCBI chr19:43,193,264...43,215,281
Ensembl chr19:43,193,257...43,215,281
JBrowse link
G Abcd1 ATP binding cassette subfamily D member 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of ABCD1 mRNA CTD PMID:27776689 NCBI chr  X:157,073,860...157,095,652
Ensembl chr  X:157,072,736...157,095,274
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of ABCG5 gene CTD PMID:16495775 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207
JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of ACACA intron CTD PMID:27776689 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain increases expression EXP Ethylnitrosourea results in increased expression of ACADL mRNA CTD PMID:15954086 NCBI chr 9:73,833,368...73,871,857
Ensembl chr 9:73,833,388...73,871,888
JBrowse link
G Actn4 actinin alpha 4 increases expression EXP Ethylnitrosourea results in increased expression of ACTN4 mRNA CTD PMID:15954086 NCBI chr 1:87,078,012...87,147,347
Ensembl chr 1:87,078,020...87,147,333
JBrowse link
G Adam1a ADAM metallopeptidase domain 1a increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of ADAM1A mRNA CTD PMID:27776689 NCBI chr12:40,533,731...40,536,632
Ensembl chr12:40,533,632...40,536,620
JBrowse link
G Adgrf4 adhesion G protein-coupled receptor F4 increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of ADGRF4 gene CTD PMID:16495775 NCBI chr 9:20,951,249...20,982,493
Ensembl chr 9:20,951,260...20,982,487
JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of ADGRV1 gene CTD PMID:17329413 NCBI chr 2:8,926,843...9,504,455
Ensembl chr 2:8,926,850...9,504,134
JBrowse link
G Adra2b adrenoceptor alpha 2B increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of ADRA2B gene CTD PMID:16495775 NCBI chr 3:119,805,941...119,809,987
Ensembl chr 3:119,805,941...119,809,987
JBrowse link
G Aen apoptosis enhancing nuclease increases expression ISO Ethylnitrosourea results in increased expression of AEN mRNA CTD PMID:19100860 NCBI chr 1:140,584,328...140,593,749
Ensembl chr 1:140,584,380...140,593,745
JBrowse link
G Aff1 AF4/FMR2 family, member 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of AFF1 gene CTD PMID:16724327 NCBI chr14:7,222,883...7,384,916
Ensembl chr14:7,226,586...7,384,876
JBrowse link
G Agap1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of AGAP1 mRNA CTD PMID:27776689 NCBI chr 9:96,718,901...97,034,400
Ensembl chr 9:96,621,586...97,030,163
JBrowse link
G Aip aryl-hydrocarbon receptor-interacting protein increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of AIP gene CTD PMID:27776689 NCBI chr 1:219,361,859...219,373,924
Ensembl chr 1:219,361,860...219,374,014
JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of ALDH1L2 mRNA CTD PMID:27776689 NCBI chr 7:26,375,866...26,425,838
Ensembl chr 7:26,375,866...26,425,108
JBrowse link
G Alg5 ALG5, dolichyl-phosphate beta-glucosyltransferase increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of ALG5 gene CTD PMID:15755804 NCBI chr 2:143,932,242...143,946,472
Ensembl chr 2:143,932,739...143,946,466
JBrowse link
G Alk ALK receptor tyrosine kinase multiple interactions
increases mutagenesis
ISO [Ethylnitrosourea results in increased mutagenesis of ALK protein] inhibits the reaction [crizotinib results in decreased phosphorylation of ALK protein]; [Ethylnitrosourea results in increased mutagenesis of ALK protein] which results in decreased susceptibility to crizotinib; [Ethylnitrosourea results in increased mutagenesis of ALK protein] which results in decreased susceptibility to NVP-TAE684 CTD PMID:21948233, PMID:22034911 NCBI chr 6:22,696,415...23,203,791
Ensembl chr 6:22,696,397...23,203,775
JBrowse link
G Alms1 ALMS1, centrosome and basal body associated protein increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of ALMS1 mRNA CTD PMID:27776689 NCBI chr 4:117,371,544...117,472,310
Ensembl chr 4:117,371,659...117,472,198
JBrowse link
G Ankrd11 ankyrin repeat domain 11 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of ANKRD11 gene CTD PMID:17986521 NCBI chr19:55,703,831...55,862,446
Ensembl chr19:55,703,824...55,737,500
JBrowse link
G Ankrd35 ankyrin repeat domain 35 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of ANKRD35 intron CTD PMID:27776689 NCBI chr 2:198,797,136...198,817,144
Ensembl chr 2:198,797,159...198,817,146
JBrowse link
G Ankrd6 ankyrin repeat domain 6 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of ANKRD6 mRNA CTD PMID:27776689 NCBI chr 5:48,052,610...48,167,568
Ensembl chr 5:48,052,401...48,194,294
JBrowse link
G Antxr1 ANTXR cell adhesion molecule 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of ANTXR1 intron CTD PMID:16300676 NCBI chr 4:118,946,267...119,131,202
Ensembl chr 4:118,946,268...119,131,202
JBrowse link
G Aoc3 amine oxidase, copper containing 3 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of AOC3 intron CTD PMID:27776689 NCBI chr10:89,251,370...89,259,313
Ensembl chr10:89,251,370...89,259,313
JBrowse link
G Ap2a1 adaptor related protein complex 2 subunit alpha 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of AP2A1 exon CTD PMID:16300676 NCBI chr 1:100,896,582...100,926,443
Ensembl chr 1:100,896,947...100,926,335
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of AP2M1 gene CTD PMID:27776689 NCBI chr11:84,041,184...84,047,542
Ensembl chr11:84,041,184...84,047,546
JBrowse link
G Apc APC regulator of WNT signaling pathway increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of APC gene CTD PMID:16724327 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Aplnr apelin receptor increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of APLNR 3' UTR CTD PMID:27776689 NCBI chr 3:72,540,538...72,544,183
Ensembl chr 3:72,540,538...72,544,182
JBrowse link
G Aqp2 aquaporin 2 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of AQP2 exon CTD PMID:16121255 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165
JBrowse link
G Arcn1 archain 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of ARCN1 gene CTD PMID:20502676 NCBI chr 8:49,051,257...49,075,861
Ensembl chr 8:49,051,246...49,075,892
JBrowse link
G Arl13b ADP-ribosylation factor like GTPase 13B increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of ARL13B gene CTD PMID:15755804 NCBI chr 7:1,122,567...1,188,209
Ensembl chr 7:1,122,567...1,188,209
JBrowse link
G Asip agouti signaling protein increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of A gene CTD PMID:9475716, PMID:10517996 NCBI chr 3:150,492,010...150,579,870
Ensembl chr 3:150,574,473...150,579,870
JBrowse link
G Atf7ip activating transcription factor 7 interacting protein increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of ATF7IP mRNA CTD PMID:27776689 NCBI chr 4:170,476,998...170,563,063
Ensembl chr 4:170,518,673...170,559,532
JBrowse link
G Atrx ATRX, chromatin remodeler increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of ATRX gene CTD PMID:16495775 NCBI chr  X:76,820,110...76,979,155
Ensembl chr  X:76,692,970...76,708,878
Ensembl chr  X:76,692,970...76,708,878
JBrowse link
G Avpr1a arginine vasopressin receptor 1A increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of AVPR1A gene CTD PMID:16495775 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G Bad BCL2-associated agonist of cell death increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of BAD gene CTD PMID:27776689 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bahd1 bromo adjacent homology domain containing 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of BAHD1 gene CTD PMID:27776689 NCBI chr 3:110,708,790...110,732,038
Ensembl chr 3:110,723,481...110,732,060
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
affects expression
ISO
EXP
Ethylnitrosourea results in increased expression of BAX mRNA
Ethylnitrosourea affects the expression of BAX mRNA
CTD PMID:11356909, PMID:15954086, PMID:19100860, PMID:30944280 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcap31 B-cell receptor-associated protein 31 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of BCAP31 gene CTD PMID:27776689 NCBI chr  X:157,094,365...157,126,397
Ensembl chr  X:157,095,937...157,126,393
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of BCAT2 gene CTD PMID:14755340 NCBI chr 1:101,553,900...101,572,103
Ensembl chr 1:101,554,642...101,572,080
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression ISO Ethylnitrosourea results in increased expression of BCL2 mRNA CTD PMID:30944280 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression ISO Ethylnitrosourea results in increased expression of BCL2L1 mRNA CTD PMID:30944280 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bdnf brain-derived neurotrophic factor increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of BDNF gene CTD PMID:16495775 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bmp5 bone morphogenetic protein 5 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of BMP5 gene CTD PMID:9475716, PMID:9825669, PMID:10517996 NCBI chr 8:82,669,466...82,950,273
Ensembl chr 8:82,878,941...82,950,273
JBrowse link
G Bop1 BOP1 ribosomal biogenesis factor increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of BOP1 gene CTD PMID:27776689 NCBI chr 7:117,514,529...117,538,342
Ensembl chr 7:117,514,533...117,538,342
JBrowse link
G Brwd1 bromodomain and WD repeat domain containing 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of BRWD1 gene CTD PMID:18353305 NCBI chr11:36,338,080...36,430,473
Ensembl chr11:36,337,635...36,430,413
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Ethylnitrosourea results in increased expression of BTG2 mRNA CTD PMID:19100860 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G C3 complement C3 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of C3 mRNA CTD PMID:27776689 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Cabcoco1 ciliary associated calcium binding coiled-coil 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CABCOCO1 mRNA CTD PMID:27776689 NCBI chr20:21,316,770...21,426,036
Ensembl chr20:21,316,826...21,426,034
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CACNA1A exon; Ethylnitrosourea results in increased mutagenesis of CACNA1A gene CTD PMID:16724327, PMID:17376154 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CACNA2D2 gene CTD PMID:16724327 NCBI chr 8:116,154,661...116,285,643
Ensembl chr 8:116,154,736...116,284,985
JBrowse link
G Capsl calcyphosine-like increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CAPSL exon; Ethylnitrosourea results in increased mutagenesis of CAPSL intron CTD PMID:16300676 NCBI chr 2:58,724,855...58,755,220
Ensembl chr 2:58,724,855...58,747,843
JBrowse link
G Card11 caspase recruitment domain family, member 11 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CARD11 gene CTD PMID:16724327 NCBI chr12:15,700,600...15,844,512
Ensembl chr12:15,700,825...15,844,512
JBrowse link
G Casp3 caspase 3 increases cleavage ISO Ethylnitrosourea results in increased cleavage of CASP3 protein CTD PMID:28549617 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cckbr cholecystokinin B receptor increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of CCKBR gene CTD PMID:16495775 NCBI chr 1:170,262,218...170,272,298
Ensembl chr 1:170,262,156...170,272,298
JBrowse link
G Ccnd1 cyclin D1 increases expression EXP Ethylnitrosourea results in increased expression of CCND1 mRNA CTD PMID:15954086 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne2 cyclin E2 multiple interactions
decreases expression
ISO DICER1 protein affects the reaction [Ethylnitrosourea results in decreased expression of CCNE2 mRNA]; Ethylnitrosourea affects the reaction [DICER1 protein affects the expression of CCNE2 mRNA] CTD PMID:24478143 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Ccng1 cyclin G1 increases expression ISO
EXP
Ethylnitrosourea results in increased expression of CCNG1 mRNA CTD PMID:15954086, PMID:19100860 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CCT8 mRNA CTD PMID:27776689 NCBI chr11:27,130,172...27,141,881
Ensembl chr11:27,130,172...27,141,881
JBrowse link
G Cd302 CD302 molecule increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CD302 intron CTD PMID:27776689 NCBI chr 3:46,327,382...46,361,092
Ensembl chr 3:46,327,383...46,361,092
JBrowse link
G Cd36 CD36 molecule increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CD36 gene CTD PMID:15690042, PMID:16724327 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd4 Cd4 molecule increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CD4 intron CTD PMID:27776689 NCBI chr 4:157,381,862...157,408,357
Ensembl chr 4:157,383,052...157,408,176
JBrowse link
G Cd59 CD59 molecule increases mutagenesis
decreases lipidation
multiple interactions
ISO
EXP
Ethylnitrosourea results in increased mutagenesis of CD59 protein
Ethylnitrosourea results in decreased lipidation of CD59 protein
[Ethylnitrosourea results in increased mutagenesis of and results in decreased activity of PIGA protein] which affects the localization of CD59 protein; [Ethylnitrosourea results in increased mutagenesis of PIGA gene] which results in decreased expression of CD59 protein
CTD PMID:17045307, PMID:19965957, PMID:20202993, PMID:27931811 NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621
JBrowse link
G Cd83 CD83 molecule increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CD83 gene CTD PMID:16724327 NCBI chr17:24,416,651...24,435,790
Ensembl chr17:24,416,651...24,435,790
JBrowse link
G Cdan1 codanin 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CDAN1 mRNA CTD PMID:27776689 NCBI chr 3:112,660,839...112,676,596
Ensembl chr 3:112,663,383...112,676,556
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
decreases expression
multiple interactions
EXP
ISO
Ethylnitrosourea results in increased expression of CDKN1A mRNA
Ethylnitrosourea results in decreased expression of CDKN1A mRNA
DICER1 protein affects the reaction [Ethylnitrosourea results in decreased expression of CDKN1A mRNA]
CTD PMID:15954086, PMID:19100860, PMID:24211769, PMID:24478143 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases response to substance
multiple interactions
decreases expression
ISO CDKN2A gene mutant form results in increased susceptibility to Ethylnitrosourea
Phytic Acid inhibits the reaction [Ethylnitrosourea results in decreased expression of CDKN2A]
CTD PMID:17943659, PMID:21154115 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C decreases expression ISO Ethylnitrosourea results in decreased expression of CDKN2C protein CTD PMID:28549617 NCBI chr 5:129,347,731...129,352,886
Ensembl chr 5:129,347,732...129,352,886
JBrowse link
G Celsr1 cadherin, EGF LAG seven-pass G-type receptor 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CELSR1 gene CTD PMID:16724327 NCBI chr 7:126,774,010...126,914,085
Ensembl chr 7:126,775,516...126,913,585
JBrowse link
G Cep104 centrosomal protein 104 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CEP104 gene CTD PMID:27776689 NCBI chr 5:171,262,278...171,294,560
Ensembl chr 5:171,262,278...171,294,559
JBrowse link
G Cep95 centrosomal protein 95 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CEP95 mRNA CTD PMID:27776689 NCBI chr10:94,988,362...95,017,774
Ensembl chr10:94,988,362...95,016,344
JBrowse link
G Chd9 chromodomain helicase DNA binding protein 9 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CHD9 mRNA CTD PMID:27776689 NCBI chr19:17,364,969...17,517,757
Ensembl chr19:17,366,828...17,494,585
JBrowse link
G Chek2 checkpoint kinase 2 decreases expression ISO Ethylnitrosourea results in decreased expression of CHEK2 protein CTD PMID:28549617 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Chgb chromogranin B increases expression EXP Ethylnitrosourea results in increased expression of CHGB mRNA CTD PMID:15954086 NCBI chr 3:125,428,050...125,441,601
Ensembl chr 3:125,428,260...125,441,594
JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of CHRM5 gene CTD PMID:16495775 NCBI chr 3:103,966,451...104,018,815
Ensembl chr 3:103,966,451...104,018,861
JBrowse link
G Chrna6 cholinergic receptor nicotinic alpha 6 subunit increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of CHRNA6 gene CTD PMID:16495775 NCBI chr16:68,860,018...68,866,718
Ensembl chr16:68,860,018...68,866,718
JBrowse link
G Chrnd cholinergic receptor nicotinic delta subunit increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of CHRND gene CTD PMID:16495775 NCBI chr 9:94,286,550...94,294,968
Ensembl chr 9:94,286,550...94,294,968
JBrowse link
G Chst14 carbohydrate sulfotransferase 14 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CHST14 intron; Ethylnitrosourea results in increased mutagenesis of CHST14 mRNA CTD PMID:27776689 NCBI chr 3:110,734,105...110,736,162
Ensembl chr 3:110,734,105...110,736,162
JBrowse link
G Col1a2 collagen type I alpha 2 chain increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of COL1A2 intron CTD PMID:27776689 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Col4a1 collagen type IV alpha 1 chain increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of COL4A1 gene CTD PMID:16724327 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Col6a3 collagen type VI alpha 3 chain increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of COL6A3 mRNA CTD PMID:27776689 NCBI chr 9:97,926,784...98,004,643
Ensembl chr 9:97,926,787...98,004,546
JBrowse link
G Commd4 COMM domain containing 4 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of COMMD4 gene CTD PMID:27776689 NCBI chr 8:61,833,340...61,836,872
Ensembl chr 8:61,833,326...61,836,945
JBrowse link
G Cox11 cytochrome c oxidase copper chaperone COX11 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of COX11 mRNA CTD PMID:27776689 NCBI chr10:78,168,691...78,173,845
NCBI chr10:78,102,620...78,174,584
Ensembl chr10:78,111,050...78,174,584
JBrowse link
G Cpn1 carboxypeptidase N subunit 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CPN1 mRNA CTD PMID:27776689 NCBI chr 1:263,733,887...263,762,758
Ensembl chr 1:263,733,519...263,762,785
JBrowse link
G Cryaa crystallin, alpha A increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CRYAA gene CTD PMID:16724327 NCBI chr20:10,438,444...10,442,189
Ensembl chr20:10,438,444...10,442,187
JBrowse link
G Crybg2 crystallin beta-gamma domain containing 2 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CRYBG2 intron CTD PMID:27776689 NCBI chr 5:152,289,492...152,321,539
Ensembl chr 5:152,290,084...152,321,541
JBrowse link
G Crygb crystallin, gamma B increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CRYGB exon CTD PMID:15878859 NCBI chr 9:71,796,204...71,798,265
Ensembl chr 9:71,796,204...71,798,265
JBrowse link
G Ctnna1 catenin alpha 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CTNNA1 intron CTD PMID:27776689 NCBI chr18:27,923,229...28,055,972
Ensembl chr18:27,923,572...28,055,960
JBrowse link
G Ctrb1 chymotrypsinogen B1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CTRB1 intron CTD PMID:27776689 NCBI chr19:43,906,344...43,911,020
Ensembl chr19:43,906,292...43,911,057
JBrowse link
G Cux2 cut-like homeobox 2 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CUX2 intron CTD PMID:27776689 NCBI chr12:40,016,774...40,221,067
Ensembl chr12:40,018,937...40,219,291
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CYP17A1 mRNA CTD PMID:27776689 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 increases expression ISO Ethylnitrosourea results in increased expression of CYP21A1 mRNA CTD PMID:19100860 NCBI chr20:4,486,213...4,489,358
Ensembl chr20:4,486,219...4,489,550
JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of CYP46A1 mRNA CTD PMID:27776689 NCBI chr 6:132,242,328...132,273,788
Ensembl chr 6:132,242,328...132,273,787
JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of CYSLTR2 gene CTD PMID:16495775 NCBI chr15:54,903,290...54,941,742
Ensembl chr15:54,905,274...54,906,203
JBrowse link
G Dalrd3 DALR anticodon binding domain containing 3 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DALRD3 mRNA CTD PMID:27776689 NCBI chr 8:117,355,943...117,358,819
Ensembl chr 8:117,355,943...117,358,818
JBrowse link
G Dbh dopamine beta-hydroxylase increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of DBH gene CTD PMID:16495775 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Dcbld2 discoidin, CUB and LCCL domain containing 2 increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of DCBLD2 gene CTD PMID:16495775 NCBI chr11:44,237,814...44,292,884
Ensembl chr11:44,241,111...44,292,884
JBrowse link
G Dcdc5 doublecortin domain containing 5 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DCDC5 mRNA CTD PMID:27776689 NCBI chr 3:97,207,500...97,435,067
Ensembl chr 3:97,256,881...97,433,651
JBrowse link
G Dchs1 dachsous cadherin-related 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DCHS1 mRNA CTD PMID:27776689 NCBI chr 1:170,594,981...170,629,062
Ensembl chr 1:170,594,822...170,628,915
JBrowse link
G Dclre1b DNA cross-link repair 1B increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DCLRE1B mRNA CTD PMID:27776689 NCBI chr 2:206,285,085...206,293,599
Ensembl chr 2:206,285,089...206,293,599
JBrowse link
G Dcp1b decapping mRNA 1B increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DCP1B mRNA CTD PMID:27776689 NCBI chr 4:151,249,654...151,287,018
Ensembl chr 4:151,250,041...151,285,702
JBrowse link
G Ddx5 DEAD-box helicase 5 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DDX5 gene CTD PMID:27776689 NCBI chr10:94,979,759...94,988,461
Ensembl chr10:94,980,928...94,988,461
JBrowse link
G Depdc1b DEP domain containing 1B increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DEPDC1B intron CTD PMID:27776689 NCBI chr 2:39,980,796...40,069,982
Ensembl chr 2:40,000,313...40,069,975
JBrowse link
G Derl3 derlin 3 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DERL3 mRNA CTD PMID:27776689 NCBI chr20:13,692,102...13,707,645
Ensembl chr20:13,704,314...13,706,205
JBrowse link
G Dffb DNA fragmentation factor subunit beta increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DFFB intron CTD PMID:27776689 NCBI chr 5:171,250,559...171,261,875
Ensembl chr 5:171,249,633...171,262,119
JBrowse link
G Dhx37 DEAH-box helicase 37 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DHX37 mRNA CTD PMID:27776689 NCBI chr12:36,594,058...36,614,165
Ensembl chr12:36,594,047...36,614,210
JBrowse link
G Dhx38 DEAH-box helicase 38 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DHX38 mRNA CTD PMID:27776689 NCBI chr19:42,110,291...42,127,540
Ensembl chr19:42,110,327...42,127,542
JBrowse link
G Dicer1 dicer 1 ribonuclease III multiple interactions ISO DICER1 protein affects the reaction [Ethylnitrosourea results in decreased expression of CCNE2 mRNA]; DICER1 protein affects the reaction [Ethylnitrosourea results in decreased expression of CDKN1A mRNA]; DICER1 protein affects the reaction [Ethylnitrosourea results in decreased expression of GADD45B mRNA]; DICER1 protein affects the reaction [Ethylnitrosourea results in decreased expression of JUN mRNA]; Ethylnitrosourea affects the reaction [DICER1 protein affects the expression of CCNE2 mRNA] CTD PMID:24478143 NCBI chr 6:128,388,084...128,453,234
Ensembl chr 6:128,388,053...128,434,183
JBrowse link
G Dip2a disco-interacting protein 2 homolog A increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DIP2A intron CTD PMID:27776689 NCBI chr20:13,044,056...13,127,971
Ensembl chr20:13,044,104...13,127,487
JBrowse link
G Disp1 dispatched RND transporter family member 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DISP1 gene CTD PMID:15755804, PMID:16724327 NCBI chr13:101,451,932...101,597,570
Ensembl chr13:101,451,932...101,597,570
JBrowse link
G Dmd dystrophin increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DMD gene CTD PMID:16724327 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link
G Dnah5 dynein, axonemal, heavy chain 5 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DNAH5 mRNA CTD PMID:27776689 NCBI chr 2:80,947,730...81,143,997
NCBI chr 2:81,159,060...81,337,560
Ensembl chr 2:80,948,658...81,143,447
JBrowse link
G Dnajc2 DnaJ heat shock protein family (Hsp40) member C2 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DNAJC2 gene CTD PMID:27776689 NCBI chr 4:9,881,505...9,908,693
Ensembl chr 4:9,882,904...9,908,689
JBrowse link
G Dnm3 dynamin 3 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DNM3 gene CTD PMID:27776689 NCBI chr13:79,906,711...80,379,967
Ensembl chr13:79,910,382...80,379,929
JBrowse link
G Dnmt1 DNA methyltransferase 1 increases expression ISO Ethylnitrosourea results in increased expression of DNMT1 CTD PMID:21154115 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Drd1 dopamine receptor D1 increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of DRD1 gene CTD PMID:16495775 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Dscam DS cell adhesion molecule increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DSCAM mRNA CTD PMID:27776689 NCBI chr11:37,004,776...37,599,866
Ensembl chr11:37,004,902...37,253,776
JBrowse link
G Dst dystonin increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DST gene CTD PMID:16724327 NCBI chr 9:37,902,336...38,296,961
Ensembl chr 9:37,902,303...38,196,273
JBrowse link
G Dtx3l deltex E3 ubiquitin ligase 3L increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DTX3L mRNA CTD PMID:27776689 NCBI chr11:67,758,093...67,767,623
NCBI chr11:67,768,542...67,772,428
Ensembl chr11:67,757,928...67,767,622
JBrowse link
G Dvl3 dishevelled segment polarity protein 3 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DVL3 mRNA CTD PMID:27776689 NCBI chr11:84,051,177...84,068,479
Ensembl chr11:84,051,078...84,068,302
JBrowse link
G Dync1h1 dynein cytoplasmic 1 heavy chain 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DYNC1H1 gene CTD PMID:16724327 NCBI chr 6:134,958,854...135,085,769
Ensembl chr 6:134,958,854...135,085,769
JBrowse link
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of DYNC2H1 gene CTD PMID:15755804 NCBI chr 8:5,217,054...5,436,969
Ensembl chr 8:5,217,217...5,429,581
JBrowse link
G Edn3 endothelin 3 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of EDN3 exon CTD PMID:17516928 NCBI chr 3:172,856,730...172,879,276
Ensembl chr 3:172,856,733...172,880,450
JBrowse link
G Ednrb endothelin receptor type B increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of EDNRB gene CTD PMID:9475716, PMID:17174358 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Egfr epidermal growth factor receptor increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of EGFR gene CTD PMID:15366372, PMID:16724327 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Eif3j eukaryotic translation initiation factor 3, subunit J increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of EIF3J gene CTD PMID:27776689 NCBI chr 3:113,976,687...113,998,925
Ensembl chr 3:113,976,687...113,998,922
JBrowse link
G Emx2 empty spiracles homeobox 2 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of EMX2 gene CTD PMID:16724327 NCBI chr 1:280,633,938...280,640,946
Ensembl chr 1:280,633,938...280,640,946
JBrowse link
G Enam enamelin increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of ENAM exon; Ethylnitrosourea results in increased mutagenesis of ENAM intron CTD PMID:15649948, PMID:17652207 NCBI chr14:21,194,635...21,219,529
Ensembl chr14:21,194,664...21,219,454
JBrowse link
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of EPB41L5 gene CTD PMID:15755804 NCBI chr13:35,622,472...35,673,449
Ensembl chr13:35,580,098...35,668,968
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP Ethylnitrosourea results in increased expression of EPHX1 mRNA CTD PMID:15954086 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of ERBB2 gene CTD PMID:16651423 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Exosc5 exosome component 5 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of EXOSC5 gene CTD PMID:27776689 NCBI chr 1:82,452,104...82,461,607
Ensembl chr 1:82,452,469...82,461,606
JBrowse link
G Fah fumarylacetoacetate hydrolase increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of FAH gene CTD PMID:16180137, PMID:16724327 NCBI chr 1:146,713,663...146,736,339
Ensembl chr 1:146,713,676...146,736,261
JBrowse link
G Fam216a family with sequence similarity 216, member A increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of FAM216A gene CTD PMID:27776689 NCBI chr12:39,679,688...39,688,831
Ensembl chr12:39,679,688...39,688,823
JBrowse link
G Fam98a family with sequence similarity 98, member A increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of FAM98A mRNA CTD PMID:27776689 NCBI chr 6:21,051,327...21,065,986
Ensembl chr 6:21,051,327...21,065,986
JBrowse link
G Fancc FA complementation group C increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of FANCC mRNA CTD PMID:27776689 NCBI chr17:826,512...955,703
Ensembl chr17:833,509...955,615
JBrowse link
G Fat2 FAT atypical cadherin 2 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of FAT2 mRNA CTD PMID:27776689 NCBI chr10:40,583,025...40,682,598
Ensembl chr10:40,584,403...40,657,861
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression EXP Ethylnitrosourea results in decreased expression of FDFT1 mRNA CTD PMID:15954086 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fech ferrochelatase increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of FECH gene CTD PMID:16724327 NCBI chr18:59,941,992...59,975,192
Ensembl chr18:59,941,992...59,975,192
JBrowse link
G Fmn2 formin 2 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of FMN2 mRNA CTD PMID:27776689 NCBI chr13:92,569,256...92,887,302 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Ethylnitrosourea results in increased expression of FOS mRNA CTD PMID:19100860 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxf2 forkhead box F2 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of FOXF2 gene CTD PMID:16724327 NCBI chr17:34,150,417...34,156,450 JBrowse link
G Foxn1 forkhead box N1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of FOXN1 gene CTD PMID:16972005 NCBI chr10:65,621,142...65,634,666
Ensembl chr10:65,621,257...65,634,666
JBrowse link
G Frem1 Fras1 related extracellular matrix 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of FREM1 gene CTD PMID:23221805 NCBI chr 5:101,018,009...101,166,794
Ensembl chr 5:101,020,448...101,166,651
JBrowse link
G Fryl FRY like transcription coactivator increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of FRYL mRNA CTD PMID:27776689 NCBI chr14:37,551,109...37,757,511
Ensembl chr14:37,551,940...37,756,149
JBrowse link
G Fshr follicle stimulating hormone receptor increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of FSHR gene CTD PMID:16495775 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression
decreases expression
multiple interactions
ISO Ethylnitrosourea results in increased expression of GADD45B mRNA
Ethylnitrosourea results in decreased expression of GADD45B mRNA
DICER1 protein affects the reaction [Ethylnitrosourea results in decreased expression of GADD45B mRNA]
CTD PMID:19100860, PMID:24478143 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
JBrowse link
G Gal3st3 galactose-3-O-sulfotransferase 3 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GAL3ST3 gene CTD PMID:27776689 NCBI chr 1:220,668,544...220,678,300
Ensembl chr 1:220,668,544...220,678,299
JBrowse link
G Gata1 GATA binding protein 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GATA1 gene CTD PMID:16966598 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066
JBrowse link
G Gata6 GATA binding protein 6 multiple interactions
increases activity
ISO Ethylnitrosourea promotes the reaction [GATA6 protein binds to KRAS exon]
Ethylnitrosourea results in increased activity of GATA6 protein
CTD PMID:16271038 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338
JBrowse link
G Gck glucokinase increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GCK exon; Ethylnitrosourea results in increased mutagenesis of GCK gene CTD PMID:15102714, PMID:15161764, PMID:16724327, PMID:18056790 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Gcm2 glial cells missing transcription factor 2 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GCM2 mRNA CTD PMID:27776689 NCBI chr17:21,490,402...21,499,516
Ensembl chr17:21,490,402...21,499,516
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Ethylnitrosourea results in increased expression of GDF15 mRNA CTD PMID:19100860 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor decreases expression ISO Ethylnitrosourea results in decreased expression of GFI1 protein CTD PMID:28549617 NCBI chr14:3,058,035...3,073,332
Ensembl chr14:3,058,993...3,068,371
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GGT1 gene CTD PMID:16724327 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Gja1 gap junction protein, alpha 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GJA1 exon; Ethylnitrosourea results in increased mutagenesis of GJA1 gene CTD PMID:15548583, PMID:16155213, PMID:16724327 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gja8 gap junction protein, alpha 8 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GJA8 gene CTD PMID:16724327 NCBI chr 2:199,050,854...199,052,470
Ensembl chr 2:199,050,854...199,052,470
JBrowse link
G Gjb1 gap junction protein, beta 1 multiple interactions EXP [Ethylnitrosourea co-treated with chlorendic acid] results in decreased expression of GJB1 protein; [Ethylnitrosourea co-treated with ciprofibrate] results in decreased expression of GJB1 protein; [Ethylnitrosourea co-treated with Dioxins] results in decreased expression of GJB1 protein; [Ethylnitrosourea co-treated with Phenobarbital] results in decreased expression of GJB1 protein; [Ethylnitrosourea co-treated with pirinixic acid] results in decreased expression of GJB1 protein; [Ethylnitrosourea co-treated with Tamoxifen] results in decreased expression of GJB1 protein CTD PMID:1973356 NCBI chr  X:71,272,030...71,279,973
Ensembl chr  X:71,272,042...71,279,977
JBrowse link
G Gjb2 gap junction protein, beta 2 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GJB2 gene CTD PMID:16724327 NCBI chr15:37,377,313...37,394,494
Ensembl chr15:37,377,316...37,383,277
JBrowse link
G Gli1 GLI family zinc finger 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GLI1 mRNA CTD PMID:27776689 NCBI chr 7:70,620,794...70,633,171
Ensembl chr 7:70,620,766...70,630,338
JBrowse link
G Gli3 GLI family zinc finger 3 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GLI3 gene CTD PMID:18397875 NCBI chr17:52,294,942...52,569,036
Ensembl chr17:52,294,942...52,569,036
JBrowse link
G Glra1 glycine receptor, alpha 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GLRA1 exon CTD PMID:16964444 NCBI chr10:40,851,955...40,954,364
Ensembl chr10:40,855,559...40,953,651
JBrowse link
G Gna11 G protein subunit alpha 11 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GNA11 gene CTD PMID:16724327 NCBI chr 7:11,033,400...11,047,284
Ensembl chr 7:11,033,317...11,047,437
JBrowse link
G Gnaq G protein subunit alpha q increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GNAQ gene CTD PMID:16724327 NCBI chr 1:233,382,778...233,622,584
Ensembl chr 1:233,382,708...233,622,786
JBrowse link
G Gnas GNAS complex locus increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GNAS gene CTD PMID:16724327 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Gnptg N-acetylglucosamine-1-phosphate transferase subunit gamma increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GNPTG intron CTD PMID:27776689 NCBI chr10:14,593,050...14,597,995
Ensembl chr10:14,593,056...14,597,969
JBrowse link
G Gnrhr gonadotropin releasing hormone receptor increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GNRHR gene CTD PMID:15625238 NCBI chr14:23,480,462...23,498,450
Ensembl chr14:23,480,462...23,498,450
JBrowse link
G Gpatch2 G patch domain containing 2 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GPATCH2 mRNA CTD PMID:27776689 NCBI chr13:105,684,300...105,824,405
Ensembl chr13:105,684,420...105,815,606
JBrowse link
G Gpkow G patch domain and KOW motifs increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GPKOW mRNA CTD PMID:27776689 NCBI chr  X:15,636,567...15,651,332
Ensembl chr  X:15,636,563...15,651,332
JBrowse link
G Gpr137 G protein-coupled receptor 137 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GPR137 intron CTD PMID:27776689 NCBI chr 1:222,194,266...222,197,252
Ensembl chr 1:222,194,266...222,197,252
JBrowse link
G Gpr153 G protein-coupled receptor 153 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GPR153 gene CTD PMID:27776689 NCBI chr 5:169,450,275...169,463,878
Ensembl chr 5:169,452,493...169,462,713
JBrowse link
G Gpr33 G protein-coupled receptor 33 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GPR33 gene CTD PMID:16720677 NCBI chr 6:72,804,843...72,805,848
Ensembl chr 6:72,804,843...72,805,848
JBrowse link
G Grid2 glutamate ionotropic receptor delta type subunit 2 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GRID2 gene CTD PMID:16724327 NCBI chr 4:94,068,112...95,476,864
Ensembl chr 4:94,696,965...95,442,778
JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of GRIK1 gene CTD PMID:16495775 NCBI chr11:27,811,954...28,213,940
Ensembl chr11:27,811,957...27,971,359
JBrowse link
G Grm6 glutamate metabotropic receptor 6 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GRM6 exon CTD PMID:17430614 NCBI chr10:36,345,503...36,363,416
Ensembl chr10:36,345,939...36,360,665
JBrowse link
G Grm8 glutamate metabotropic receptor 8 increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of GRM8 gene CTD PMID:16495775 NCBI chr 4:54,474,344...55,409,526
Ensembl chr 4:54,474,136...55,407,922
JBrowse link
G Grpr gastrin releasing peptide receptor increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of GRPR gene CTD PMID:16495775 NCBI chr  X:32,746,259...32,786,266
Ensembl chr  X:32,745,873...32,786,359
JBrowse link
G Gsdme gasdermin E increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of GSDME mRNA CTD PMID:27776689 NCBI chr 4:79,934,075...79,999,678
Ensembl chr 4:79,934,887...79,989,572
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases expression ISO Ethylnitrosourea results in decreased expression of GSK3B protein CTD PMID:28549617 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects response to substance ISO GSTT1 gene polymorphism affects the susceptibility to Ethylnitrosourea CTD PMID:17158087 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of HADHB exon CTD PMID:17116638 NCBI chr 6:27,555,408...27,589,539
Ensembl chr 6:27,555,412...27,582,995
JBrowse link
G Hdac1 histone deacetylase 1 increases expression ISO Ethylnitrosourea results in increased expression of HDAC1 CTD PMID:21154115 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hectd1 HECT domain E3 ubiquitin protein ligase 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of HECTD1 gene CTD PMID:15755804 NCBI chr 6:72,509,658...72,596,285
Ensembl chr 6:72,510,255...72,596,446
JBrowse link
G Hes3 hes family bHLH transcription factor 3 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of HES3 mRNA CTD PMID:27776689 NCBI chr 5:169,463,196...169,469,795
Ensembl chr 5:169,464,989...169,467,153
JBrowse link
G Hfe homeostatic iron regulator increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of HFE mRNA CTD PMID:27776689 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Hikeshi heat shock protein nuclear import factor increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of HIKESHI gene CTD PMID:16157679 NCBI chr 1:154,147,098...154,170,429
Ensembl chr 1:154,142,836...154,170,409
JBrowse link
G Hmcn2 hemicentin 2 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of HMCN2 3' UTR; Ethylnitrosourea results in increased mutagenesis of HMCN2 intron; Ethylnitrosourea results in increased mutagenesis of HMCN2 mRNA CTD PMID:27776689 NCBI chr 3:10,384,873...10,536,529 JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression EXP Ethylnitrosourea results in decreased expression of HMGCS1 mRNA CTD PMID:15954086 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Ethylnitrosourea results in increased expression of HMOX1 mRNA CTD PMID:19100860 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hoxd12 homeo box D12 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of HOXD12 gene CTD PMID:19108020 NCBI chr 3:61,597,382...61,598,503
Ensembl chr 3:61,597,382...61,598,503
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases mutagenesis EXP
ISO
Ethylnitrosourea results in increased mutagenesis of HPRT1 gene
Ethylnitrosourea results in increased mutagenesis of HPRT gene
CTD PMID:22167886, PMID:32529823 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Hr HR, lysine demethylase and nuclear receptor corepressor increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of HR exon; Ethylnitrosourea results in increased mutagenesis of HR gene CTD PMID:16455232, PMID:16461637, PMID:16724327 NCBI chr15:52,241,801...52,261,276
Ensembl chr15:52,241,801...52,261,276
JBrowse link
G Hras HRas proto-oncogene, GTPase increases response to substance ISO HRAS protein results in increased susceptibility to Ethylnitrosourea CTD PMID:11182032, PMID:26558449 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hrc histidine rich calcium binding protein increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of HRC mRNA CTD PMID:27776689 NCBI chr 1:101,324,788...101,328,391
Ensembl chr 1:101,324,652...101,328,435
JBrowse link
G Hsf1 heat shock transcription factor 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of HSF1 3' UTR CTD PMID:27776689 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of HSP90AB1 gene CTD PMID:16495775 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Htt huntingtin increases mutagenesis EXP Ethylnitrosourea results in increased mutagenesis of HTT gene CTD PMID:16495775 NCBI chr14:81,105,139...81,254,637
Ensembl chr14:81,105,139...81,254,637
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression EXP Ethylnitrosourea results in increased expression of ID1 mRNA CTD PMID:15954086 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein increases expression EXP Ethylnitrosourea results in increased expression of ID3 mRNA CTD PMID:15954086 NCBI chr 5:154,489,603...154,491,172
Ensembl chr 5:154,489,590...154,491,223
JBrowse link
G Ifi35 interferon-induced protein 35 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of IFI35 gene CTD PMID:27776689 NCBI chr10:89,358,376...89,366,628
Ensembl chr10:89,358,376...89,366,626
JBrowse link
G Ift172 intraflagellar transport 172 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of IFT172 gene CTD PMID:15755804 NCBI chr 6:26,390,686...26,485,459 JBrowse link
G Ift88 intraflagellar transport 88 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of IFT88 gene CTD PMID:15755804, PMID:16724327 NCBI chr15:37,690,417...37,786,855
Ensembl chr15:37,691,345...37,784,924
JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of IGF1R gene CTD PMID:16461637 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of IKZF1 gene CTD PMID:15790496 NCBI chr14:91,782,281...91,867,828
Ensembl chr14:91,782,354...91,867,424
JBrowse link
G Il7 interleukin 7 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of IL7 exon CTD PMID:17151827, PMID:17179092 NCBI chr 2:96,427,884...96,474,979
Ensembl chr 2:96,439,286...96,474,977
JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha increases expression EXP Ethylnitrosourea results in increased expression of INA mRNA CTD PMID:15954086 NCBI chr 1:266,782,835...266,794,389
Ensembl chr 1:266,781,617...266,794,431
JBrowse link
G Ins2 insulin 2 increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of INS2 gene CTD PMID:18056790 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Insig1 insulin induced gene 1 decreases expression EXP Ethylnitrosourea results in decreased expression of INSIG1 mRNA CTD PMID:15954086 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Insr insulin receptor increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of INSR gene CTD PMID:18056790 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Iqck IQ motif containing K increases mutagenesis ISO Ethylnitrosourea results in increased mutagenesis of IQCK mRNA CTD PMID:27776689 NCBI chr 1:188,571,930...188,690,184
Ensembl chr 1:188,571,953...188,688,700
JBrowse link
G Irx6