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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:isoprenaline
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Accession:CHEBI:64317 term browser browse the term
Definition:A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Synonyms:exact_synonym: 4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol
 related_synonym: 1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanol;   1-(3,4-dihydroxyphenyl)-2-isopropylaminoethanol;   3,4-dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol;   Formula=C11H17NO3;   InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3;   InChIKey=JWZZKOKVBUJMES-UHFFFAOYSA-N;   N-isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine;   N-isopropylnoradrenaline;   N-isopropylnorepinephrine;   SMILES=CC(C)NCC(O)c1ccc(O)c(O)c1;   alpha-(isopropylaminomethyl)protocatechuyl alcohol;   isoprenalina;   isoprenalinum;   isopropyl noradrenaline;   isoproterenol
 xref: CAS:7683-59-2;   DrugBank:DB01064;   Drug_Central:1499;   KEGG:C07056;   KEGG:D08090;   LINCS:LSM-4311
 xref_mesh: MESH:D007545
 xref: Patent:DE723278;   Patent:US2308232;   Reaxys:2213857;   Wikipedia:Isoprenaline



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Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin increases expression ISO Isoproterenol results in increased expression of A2M mRNA CTD PMID:21335049 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO Isoproterenol results in increased expression of ABCA1 mRNA CTD PMID:20003209 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Isoproterenol results in increased expression of ABCB1A mRNA CTD PMID:20003209 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases expression EXP
ISO
Isoproterenol results in decreased expression of ABCB4 mRNA CTD PMID:24286936 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression
increases expression
ISO
EXP
Isoproterenol results in decreased expression of ABCC3 mRNA
Isoproterenol results in increased expression of ABCC3 mRNA
CTD PMID:21335049 PMID:24286936 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression ISO Isoproterenol results in increased expression of ABCC4 mRNA CTD PMID:20003209 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO Isoproterenol results in increased expression of ABCG2 mRNA CTD PMID:20003209 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase increases expression EXP Isoproterenol results in increased expression of ABHD2 mRNA CTD PMID:20211217 NCBI chr 1:133,217,403...133,298,564
Ensembl chr 1:133,217,375...133,299,061
JBrowse link
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression ISO Isoproterenol results in increased expression of ABHD4 mRNA CTD PMID:20003209 NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966
JBrowse link
G Abi3 ABI family, member 3 increases expression ISO Isoproterenol results in increased expression of ABI3 mRNA CTD PMID:20003209 NCBI chr10:80,769,819...80,780,816
Ensembl chr10:80,769,822...80,780,816
JBrowse link
G Ablim3 actin binding LIM protein family, member 3 increases expression ISO Isoproterenol results in increased expression of ABLIM3 mRNA CTD PMID:20003209 NCBI chr18:55,256,135...55,376,629
Ensembl chr18:55,257,583...55,376,380
JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions
increases phosphorylation
decreases phosphorylation
ISO
EXP
triacsin C inhibits the reaction [Isoproterenol results in increased phosphorylation of ACACA protein]
Isoproterenol results in decreased phosphorylation of ACACA protein
CTD PMID:18390901 PMID:27491814 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain multiple interactions
decreases expression
EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADL mRNA; Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADL mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADL mRNA]] CTD PMID:25045214 PMID:30303030 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases activity
decreases expression
multiple interactions
EXP Isoproterenol results in decreased activity of ACADM protein
Isoproterenol results in decreased expression of ACADM mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADM mRNA; Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADM mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADM mRNA]]
CTD PMID:19826179 PMID:25045214 PMID:30303030 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Acads acyl-CoA dehydrogenase short chain multiple interactions
decreases expression
EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADS mRNA
Isoproterenol results in decreased expression of ACADS mRNA
CTD PMID:30303030 NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain decreases expression
multiple interactions
EXP Isoproterenol results in decreased expression of ACADVL mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADVL mRNA
CTD PMID:30303030 NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
JBrowse link
G Ace angiotensin I converting enzyme multiple interactions
increases activity
EXP oleuropein inhibits the reaction [Isoproterenol results in increased activity of ACE protein] CTD PMID:26056852 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ace2 angiotensin converting enzyme 2 increases expression
multiple interactions
decreases activity
ISO
EXP
Isoproterenol results in increased expression of ACE2 mRNA
Isoproterenol results in increased expression of ACE2 protein
[Isoproterenol results in decreased activity of ACE2 protein] which results in decreased abundance of angiotensin I (1-7); xanthone inhibits the reaction [[Isoproterenol results in decreased activity of ACE2 protein] which results in decreased abundance of angiotensin I (1-7)]; xanthone inhibits the reaction [Isoproterenol results in decreased activity of ACE2 protein]
CTD PMID:20003209 PMID:20409916 PMID:36414029 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Acer2 alkaline ceramidase 2 increases expression ISO Isoproterenol results in increased expression of ACER2 mRNA CTD PMID:20003209 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of ACSL1 mRNA CTD PMID:30303030 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle multiple interactions ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of ACTA1 mRNA; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of ACTA1 mRNA] CTD PMID:10710348 NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
decreases expression
increases expression
ISO
EXP
Doxycycline inhibits the reaction [Isoproterenol results in decreased expression of ACTA2 mRNA]
Isoproterenol results in increased expression of ACTA2 mRNA; Isoproterenol results in increased expression of ACTA2 protein
Glyburide promotes the reaction [Isoproterenol results in increased expression of ACTA2 protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of ACTA2 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of ACTA2 protein]; xanthone inhibits the reaction [Isoproterenol results in increased expression of ACTA2 protein]
CTD PMID:18089841 PMID:20003209 PMID:24945829 PMID:28526319 PMID:35305975 More... NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actb actin, beta decreases expression ISO Isoproterenol results in decreased expression of ACTB mRNA CTD PMID:20003209 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Actg2 actin gamma 2, smooth muscle increases expression ISO Isoproterenol results in increased expression of ACTG2 mRNA CTD PMID:21335049 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465
JBrowse link
G Ada adenosine deaminase multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of ADA mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 multiple interactions
increases expression
EXP
ISO
bellidifolin inhibits the reaction [Isoproterenol results in increased expression of ADAM17 mRNA] CTD PMID:37528096 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Adam22 ADAM metallopeptidase domain 22 increases expression ISO Isoproterenol results in increased expression of ADAM22 mRNA CTD PMID:20003209 NCBI chr 4:25,716,055...25,970,932
Ensembl chr 4:25,715,990...25,964,962
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 increases expression EXP Isoproterenol results in increased expression of ADAM8 mRNA CTD PMID:20211217 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
JBrowse link
G Adamtsl2 ADAMTS-like 2 increases expression ISO Isoproterenol results in increased expression of ADAMTSL2 mRNA CTD PMID:20003209 NCBI chr 3:10,397,774...10,434,557
Ensembl chr 3:10,404,626...10,434,554
JBrowse link
G Adamtsl4 ADAMTS-like 4 increases expression ISO Isoproterenol results in increased expression of ADAMTSL4 mRNA CTD PMID:20003209 NCBI chr 2:183,235,634...183,247,091
Ensembl chr 2:183,235,646...183,246,848
JBrowse link
G Adcy5 adenylate cyclase 5 increases response to substance
multiple interactions
ISO ADCY5 protein results in increased susceptibility to Isoproterenol
[ADCY5 protein results in increased susceptibility to Isoproterenol] which results in decreased expression of SOD2 protein; SOD2 protein inhibits the reaction [ADCY5 protein results in increased susceptibility to Isoproterenol]
CTD PMID:12869393 PMID:23536361 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974
JBrowse link
G Adcy6 adenylate cyclase 6 affects response to substance ISO ADCY6 protein affects the susceptibility to Isoproterenol CTD PMID:12393090 NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754
JBrowse link
G Adcy9 adenylate cyclase 9 multiple interactions ISO [Isoproterenol co-treated with Miconazole] results in increased activity of ADCY9 protein alternative form CTD PMID:30607468 NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066
JBrowse link
G Add3 adducin 3 decreases expression ISO Isoproterenol results in decreased expression of ADD3 mRNA CTD PMID:21335049 NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124
JBrowse link
G Adgrd1 adhesion G protein-coupled receptor D1 increases expression ISO Isoproterenol results in increased expression of ADGRD1 mRNA CTD PMID:20003209 NCBI chr12:27,488,908...27,603,714
Ensembl chr12:27,488,908...27,603,696
JBrowse link
G Adgrf5 adhesion G protein-coupled receptor F5 increases expression ISO Isoproterenol results in increased expression of ADGRF5 mRNA CTD PMID:20003209 NCBI chr 9:17,517,596...17,624,107
Ensembl chr 9:17,520,009...17,623,968
JBrowse link
G Adgrl4 adhesion G protein-coupled receptor L4 increases expression ISO Isoproterenol results in increased expression of ADGRL4 mRNA CTD PMID:20003209 NCBI chr 2:240,354,909...240,457,231
Ensembl chr 2:240,354,941...240,457,225
JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide increases expression ISO Isoproterenol results in increased expression of ADH1 mRNA CTD PMID:20003209 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Adm adrenomedullin multiple interactions
increases expression
EXP [Phenylephrine co-treated with Isoproterenol] results in increased expression of ADM mRNA; [Phenylephrine co-treated with Isoproterenol] results in increased expression of ADM protein; ADM protein inhibits the reaction [Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]]; CALCA protein inhibits the reaction [Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]]; Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]
Isoproterenol results in increased expression of ADM mRNA; Isoproterenol results in increased expression of ADM protein
CTD PMID:12732346 PMID:17250927 PMID:17306419 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Adra1b adrenoceptor alpha 1B multiple interactions
decreases expression
ISO ADRA1B protein affects the reaction [Isoproterenol results in increased abundance of Cyclic AMP]
Isoproterenol results in decreased expression of ADRA1B mRNA
CTD PMID:12649302 PMID:20003209 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
JBrowse link
G Adrb1 adrenoceptor beta 1 multiple interactions
decreases expression
increases uptake
affects response to substance
increases activity
increases phosphorylation
ISO
EXP
[Isoproterenol binds to and results in increased activity of ADRB1 protein] which results in increased abundance of Cyclic AMP; Atenolol inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]; carvedilol inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]; CGP 12177 inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]; CGP 20712A inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]; Isoproterenol binds to and results in increased activity of ADRB1 protein; Isoproterenol inhibits the reaction [cyanopindolol binds to ADRB1 protein]; Isoproterenol inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Isoproterenol promotes the reaction [ADRB1 protein binds to ARRB1 protein]; Isoproterenol promotes the reaction [ADRB1 protein binds to ARRB2 protein]; Isoproterenol promotes the reaction [ADRB1 protein results in increased abundance of Cyclic AMP]; Isoproterenol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]
Isoproterenol results in decreased expression of ADRB1; Isoproterenol results in decreased expression of ADRB1 mRNA
ADRB1 protein promotes the reaction [Isoproterenol results in decreased expression of NPPA protein]; ADRB1 protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP]; AGT affects the reaction [Isoproterenol results in decreased expression of ADRB1 mRNA]; Isoproterenol binds to and results in increased activity of ADRB1 protein; Isoproterenol inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Metoprolol inhibits the reaction [Isoproterenol results in decreased expression of ADRB1 mRNA]
Isoproterenol results in increased uptake of ADRB1 protein
ADRB1 protein polymorphism affects the susceptibility to Isoproterenol
[ADRB3 affects the expression of ADRB1 mRNA] which affects the susceptibility to Isoproterenol
Isoproterenol results in increased phosphorylation of ADRB1 protein
CTD PMID:1312942 PMID:8096834 PMID:8723169 PMID:11159692 PMID:12761341 More... NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions
increases expression
increases phosphorylation
decreases expression
increases activity
increases uptake
affects expression
ISO
EXP
4-(1H-imidazol-4-ylmethyl)piperidine promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]; [Isoproterenol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein; [Isoproterenol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein; [Isoproterenol results in increased activity of ADRB2 protein] which results in increased chemical synthesis of Cyclic AMP; [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Isoproterenol; Atenolol inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Atenolol inhibits the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]; clobenpropit promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]; Cobalt promotes the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]; Histamine promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]; ICI 118551 inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; ICI 118551 inhibits the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]; ICI 118551 inhibits the reaction [Isoproterenol results in increased activity of ADRB2 protein]; imidazole promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]; Isoproterenol binds to and results in increased activity of ADRB2 protein; Isoproterenol inhibits the reaction [cyanopindolol binds to ADRB2 protein]; Isoproterenol promotes the reaction [ADRB2 protein binds to ARRB2 protein]; Ketotifen inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Isoproterenol]; Propranolol inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]; Zinc promotes the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]
Isoproterenol results in increased expression of ADRB2 mRNA
Isoproterenol results in increased phosphorylation of ADRB2 protein
[GNA15 protein results in increased susceptibility to Isoproterenol] which results in increased activity of ADRB2 protein; ADRB2 protein affects the reaction [Isoproterenol results in increased expression of IL18 mRNA]; CAV1 protein promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]; ICI 118551 inhibits the reaction [Isoproterenol results in increased activity of ADRB2 protein]
Isoproterenol results in decreased expression of ADRB2; Isoproterenol results in decreased expression of ADRB2 mRNA
[Isoproterenol results in increased activity of ADRB2 protein] which results in increased secretion of Histamine; ADRB2 protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP]
Isoproterenol results in increased uptake of ADRB2 protein
Isoproterenol affects the expression of ADRB2 mRNA
CTD PMID:9875846 PMID:10226872 PMID:10516654 PMID:11164953 PMID:11752207 More... NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions
increases activity
increases expression
ISO
EXP
[Isoproterenol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; Isoproterenol binds to and results in increased activity of ADRB3 protein; Isoproterenol inhibits the reaction [cyanopindolol binds to ADRB3 protein]; L 748,337 inhibits the reaction [Isoproterenol results in increased activity of ADRB3 protein]
3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [Isoproterenol results in increased activity of ADRB3 protein]; 3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [Isoproterenol results in increased expression of ADRB3 protein]; BRL 37344 promotes the reaction [Isoproterenol results in increased expression of ADRB3 mRNA]; BRL 37344 promotes the reaction [Isoproterenol results in increased expression of ADRB3 protein]; Isoproterenol binds to and results in increased activity of ADRB3 protein
[ADRB3 affects the expression of ADRB1 mRNA] which affects the susceptibility to Isoproterenol
Isoproterenol results in increased expression of ADRB3 mRNA; Isoproterenol results in increased expression of ADRB3 protein
CTD PMID:1682311 PMID:7815362 PMID:11159692 PMID:14730417 PMID:15009959 More... NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
JBrowse link
G Aen apoptosis enhancing nuclease decreases expression ISO Isoproterenol results in decreased expression of AEN mRNA CTD PMID:20003209 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
JBrowse link
G Agbl5 AGBL carboxypeptidase 5 decreases expression ISO Isoproterenol results in decreased expression of AGBL5 mRNA CTD PMID:20003209 NCBI chr 6:25,472,333...25,492,173
Ensembl chr 6:25,472,333...25,490,738
JBrowse link
G Agt angiotensinogen multiple interactions
increases expression
ISO
EXP
adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [Isoproterenol promotes the reaction [Dexamethasone results in increased expression of AGT protein]]; ICI 118551 inhibits the reaction [Isoproterenol promotes the reaction [Dexamethasone results in increased expression of AGT protein]]; Isoproterenol promotes the reaction [Dexamethasone results in increased expression of AGT protein]; Propranolol inhibits the reaction [Isoproterenol promotes the reaction [Dexamethasone results in increased expression of AGT protein]]
Propranolol inhibits the reaction [Isoproterenol results in increased expression of AGT protein]
Isoproterenol results in increased expression of AGT mRNA; Isoproterenol results in increased expression of AGT protein
AGT affects the reaction [Isoproterenol results in decreased expression of ADRB1 mRNA]; AGT affects the reaction [Isoproterenol results in decreased expression of GRK2 mRNA]; AGT inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]; Isoproterenol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Isoproterenol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; Losartan inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; Losartan promotes the reaction [Isoproterenol results in increased expression of AGT protein]; natakalim inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; Quinapril inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; Quinapril promotes the reaction [Isoproterenol results in increased expression of AGT protein]; Rutin inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; trandolapril inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; xanthone inhibits the reaction [Isoproterenol results in increased expression of AGT protein]
CTD PMID:1534315 PMID:1653766 PMID:7843740 PMID:11709406 PMID:16731636 More... NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a decreases expression ISO Isoproterenol results in decreased expression of AGTR1A mRNA CTD PMID:17350036 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Ahcy adenosylhomocysteinase increases expression ISO Isoproterenol results in increased expression of AHCY mRNA CTD PMID:20003209 NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393
JBrowse link
G Ahnak2 AHNAK nucleoprotein 2 increases expression ISO Isoproterenol results in increased expression of AHNAK2 mRNA CTD PMID:20003209 NCBI chr 6:131,830,668...131,876,311 JBrowse link
G Ahr aryl hydrocarbon receptor increases expression
decreases expression
ISO
EXP
Isoproterenol results in increased expression of AHR mRNA
Isoproterenol results in decreased expression of AHR mRNA
CTD PMID:24286936 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ahsg alpha-2-HS-glycoprotein increases expression ISO Isoproterenol results in increased expression of AHSG mRNA CTD PMID:20003209 PMID:21335049 NCBI chr11:78,121,388...78,127,998
Ensembl chr11:78,117,918...78,145,999
JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression ISO Isoproterenol results in decreased expression of AIF1 mRNA CTD PMID:20003209 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Ak4 adenylate kinase 4 decreases expression ISO Isoproterenol results in decreased expression of AK4 mRNA CTD PMID:20003209 NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
JBrowse link
G Akap1 A-kinase anchoring protein 1 decreases expression ISO Isoproterenol results in decreased expression of AKAP1 mRNA CTD PMID:20003209 NCBI chr10:73,621,021...73,654,123
Ensembl chr10:73,621,883...73,653,896
JBrowse link
G Akap13 A-kinase anchoring protein 13 increases expression ISO Isoproterenol results in increased expression of AKAP13 mRNA CTD PMID:20003209 NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions
decreases expression
decreases phosphorylation
ISO
EXP
Isoproterenol results in increased phosphorylation of AKT1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of AKT1 protein]; Isoproterenol results in increased phosphorylation of and results in increased activity of AKT1 protein; plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; swietenine inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of AKT1 protein]
Isoproterenol results in decreased expression of AKT1 mRNA
2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one promotes the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; 5-Methoxypsoralen inhibits the reaction [Isoproterenol results in decreased phosphorylation of AKT1 protein]; [Isoproterenol co-treated with POSTN protein] results in decreased expression of AKT1 mRNA; [PDE3B protein co-treated with AKT1 protein] inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]; Enalapril promotes the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; swietenine inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]
CTD PMID:15178407 PMID:15618457 PMID:15951400 PMID:16716347 PMID:17623046 More... NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases expression ISO Isoproterenol results in decreased expression of ALDH2 mRNA CTD PMID:20003209 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 decreases expression ISO Isoproterenol results in decreased expression of ALDH3A2 mRNA CTD PMID:21335049 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281
JBrowse link
G Alpk2 alpha-kinase 2 increases expression ISO Isoproterenol results in increased expression of ALPK2 mRNA CTD PMID:20003209 NCBI chr18:58,775,603...58,906,150
Ensembl chr18:58,775,605...58,906,258
JBrowse link
G Alpk3 alpha-kinase 3 decreases expression
multiple interactions
ISO Isoproterenol results in decreased expression of ALPK3 mRNA; Isoproterenol results in decreased expression of ALPK3 protein
MIR384 mRNA inhibits the reaction [Isoproterenol results in decreased expression of ALPK3 mRNA]
CTD PMID:35510648 NCBI chr 1:135,014,455...135,062,294
Ensembl chr 1:135,014,499...135,062,302
JBrowse link
G Alpp alkaline phosphatase, placental multiple interactions
increases expression
ISO Amphetamine promotes the reaction [Isoproterenol results in increased expression of ALPP mRNA]; Chlorpromazine inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA]; Clozapine inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA]; Desipramine inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA]; ICI 118551 inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA]; norfluoxetine inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA] CTD PMID:16036225 NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606
JBrowse link
G Amy2a3 amylase 2a3 multiple interactions EXP Atenolol inhibits the reaction [Isoproterenol results in increased secretion of and results in increased activity of AMY1A protein]; Isoproterenol results in increased secretion of and results in increased activity of AMY1A protein; Propranolol inhibits the reaction [Isoproterenol results in increased secretion of and results in increased activity of AMY1A protein] CTD PMID:21173550 NCBI chr 2:201,317,916...201,326,487
Ensembl chr 2:201,317,920...201,326,532
JBrowse link
G Ang angiogenin increases expression
multiple interactions
ISO Isoproterenol results in increased expression of ANG mRNA
Doxycycline inhibits the reaction [Isoproterenol results in increased expression of ANG mRNA]
CTD PMID:18089841 PMID:20003209 NCBI chr15:24,312,711...24,323,361 JBrowse link
G Angpt2 angiopoietin 2 increases expression EXP Isoproterenol results in increased expression of ANGPT2 mRNA CTD PMID:22908232 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
JBrowse link
G Angptl2 angiopoietin-like 2 decreases expression ISO Isoproterenol results in decreased expression of ANGPTL2 mRNA CTD PMID:20003209 NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178
JBrowse link
G Angptl6 angiopoietin-like 6 decreases expression ISO Isoproterenol results in decreased expression of ANGPTL6 mRNA CTD PMID:21335049 NCBI chr 8:19,413,617...19,419,925
Ensembl chr 8:19,413,619...19,419,925
JBrowse link
G Anp32a acidic nuclear phosphoprotein 32 family member A decreases expression ISO Isoproterenol results in decreased expression of ANP32A mRNA CTD PMID:20003209 PMID:21335049 NCBI chr 8:62,829,099...62,865,443
Ensembl chr 8:62,827,456...62,865,443
JBrowse link
G Anxa1 annexin A1 multiple interactions
increases expression
ISO ANXA1 affects the reaction [Isoproterenol results in decreased secretion of IL6 protein]
Isoproterenol results in increased expression of ANXA1 mRNA
CTD PMID:16835395 PMID:20003209 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Aoc1 amine oxidase, copper containing 1 multiple interactions
increases activity
EXP Cycloheximide inhibits the reaction [Isoproterenol results in increased activity of AOC1 protein]; Dactinomycin inhibits the reaction [Isoproterenol results in increased activity of AOC1 protein]; H 35-25 inhibits the reaction [Isoproterenol results in increased activity of AOC1 protein]; pimagedine inhibits the reaction [Isoproterenol results in increased activity of AOC1 protein] CTD PMID:2860926 PMID:6218830 NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840
JBrowse link
G Aoc3 amine oxidase, copper containing 3 increases expression ISO Isoproterenol results in increased expression of AOC3 mRNA CTD PMID:20003209 NCBI chr10:86,272,757...86,280,702 JBrowse link
G Aox1 aldehyde oxidase 1 increases expression ISO Isoproterenol results in increased expression of AOX1 mRNA CTD PMID:20003209 NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
JBrowse link
G Ap1b1 adaptor related protein complex 1 subunit beta 1 increases expression ISO Isoproterenol results in increased expression of AP1B1 mRNA CTD PMID:21335049 NCBI chr14:79,879,482...79,930,778
Ensembl chr14:79,879,533...79,930,778
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO Isoproterenol results in increased expression of APAF1 mRNA CTD PMID:24286936 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression ISO Isoproterenol results in increased expression of APEX1 mRNA CTD PMID:21335049 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Apln apelin multiple interactions
decreases expression
EXP Plant Extracts inhibits the reaction [Isoproterenol results in decreased expression of APLN mRNA]; Plant Extracts inhibits the reaction [Isoproterenol results in decreased expression of APLN protein]
Isoproterenol results in decreased expression of APLN mRNA; Isoproterenol results in decreased expression of APLN protein
CTD PMID:19960946 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391
JBrowse link
G Apoa2 apolipoprotein A2 increases expression ISO Isoproterenol results in increased expression of APOA2 mRNA CTD PMID:21335049 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apod apolipoprotein D increases expression ISO Isoproterenol results in increased expression of APOD mRNA CTD PMID:20003209 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305
JBrowse link
G Appbp2 amyloid beta precursor protein binding protein 2 increases expression ISO Isoproterenol results in increased expression of APPBP2 mRNA CTD PMID:20003209 NCBI chr10:70,057,774...70,099,877
Ensembl chr10:70,057,774...70,099,835
JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 increases expression ISO Isoproterenol results in increased expression of APPL2 mRNA CTD PMID:20003209 NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754
JBrowse link
G Arf2 ADP-ribosylation factor 2 decreases expression ISO Isoproterenol results in decreased expression of ARF2 mRNA CTD PMID:20003209 NCBI chr10:88,867,836...88,889,654
Ensembl chr10:88,867,836...88,889,659
JBrowse link
G Arf4 ADP-ribosylation factor 4 increases expression ISO Isoproterenol results in increased expression of ARF4 mRNA CTD PMID:21335049 NCBI chr16:1,896,692...1,913,267
Ensembl chr16:1,896,546...1,913,261
JBrowse link
G Arhgap12 Rho GTPase activating protein 12 increases expression ISO Isoproterenol results in increased expression of ARHGAP12 mRNA CTD PMID:20003209 NCBI chr17:51,588,810...51,702,417
Ensembl chr17:51,588,842...51,702,080
JBrowse link
G Arhgap18 Rho GTPase activating protein 18 decreases expression ISO Isoproterenol results in decreased expression of ARHGAP18 mRNA CTD PMID:20003209 NCBI chr 1:18,403,531...18,637,306
Ensembl chr 1:18,403,537...18,637,256
JBrowse link
G Arhgap20 Rho GTPase activating protein 20 increases expression ISO Isoproterenol results in increased expression of ARHGAP20 mRNA CTD PMID:20003209 NCBI chr 8:52,074,472...52,155,739
Ensembl chr 8:52,074,158...52,155,739
JBrowse link
G Arhgap24 Rho GTPase activating protein 24 increases expression ISO Isoproterenol results in increased expression of ARHGAP24 mRNA CTD PMID:20003209 NCBI chr14:6,800,624...7,183,877
Ensembl chr14:6,800,631...7,183,823
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases expression EXP Isoproterenol results in increased expression of ARHGDIB mRNA CTD PMID:30303030 NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658
JBrowse link
G Arid4b AT-rich interaction domain 4B increases expression ISO Isoproterenol results in increased expression of ARID4B mRNA CTD PMID:20003209 NCBI chr17:51,138,419...51,262,894
Ensembl chr17:51,138,535...51,262,906
JBrowse link
G Arid5b AT-rich interaction domain 5B increases expression ISO Isoproterenol results in increased expression of ARID5B mRNA CTD PMID:20003209 NCBI chr20:20,307,731...20,490,746
Ensembl chr20:20,307,731...20,487,433
JBrowse link
G Arl4a ADP-ribosylation factor like GTPase 4A increases expression ISO Isoproterenol results in increased expression of ARL4A mRNA CTD PMID:20003209 NCBI chr 6:57,079,496...57,084,156
Ensembl chr 6:57,078,812...57,085,066
JBrowse link
G Arnt2 aryl hydrocarbon receptor nuclear translocator 2 decreases expression
increases expression
ISO
EXP
Isoproterenol results in decreased expression of ARNT2 mRNA
Isoproterenol results in increased expression of ARNT2 mRNA
CTD PMID:24286936 NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153
JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions ISO Isoproterenol promotes the reaction [ADRB1 protein binds to ARRB1 protein] CTD PMID:18787115 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
JBrowse link
G Arrb2 arrestin, beta 2 affects localization
multiple interactions
ISO
EXP
Isoproterenol affects the localization of ARRB2 protein
ARRB2 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; ARRB2 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]; Isoproterenol promotes the reaction [ADRB1 protein binds to ARRB2 protein]; Isoproterenol promotes the reaction [ADRB2 protein binds to ARRB2 protein]; S-nitrosocysteine inhibits the reaction [Isoproterenol affects the localization of ARRB2 protein]
CTD PMID:17482545 PMID:17925438 PMID:18787115 PMID:21078978 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Arrdc2 arrestin domain containing 2 increases expression ISO Isoproterenol results in increased expression of ARRDC2 mRNA CTD PMID:20003209 NCBI chr16:18,601,897...18,606,029
Ensembl chr16:18,601,897...18,606,029
JBrowse link
G Arrdc3 arrestin domain containing 3 increases expression ISO Isoproterenol results in increased expression of ARRDC3 mRNA CTD PMID:20003209 NCBI chr 2:11,137,464...11,149,978
Ensembl chr 2:11,137,460...11,149,978
JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 decreases expression ISO Isoproterenol results in decreased expression of ASAP1 mRNA CTD PMID:20003209 NCBI chr 7:95,786,130...96,093,111
Ensembl chr 7:95,787,818...96,092,754
JBrowse link
G Asb11 ankyrin repeat and SOCS box containing 11 increases expression ISO Isoproterenol results in increased expression of ASB11 mRNA CTD PMID:20003209 NCBI chr  X:30,014,485...30,037,808
Ensembl chr  X:29,992,416...30,037,807
JBrowse link
G Ascc3 activating signal cointegrator 1 complex subunit 3 increases expression ISO Isoproterenol results in increased expression of ASCC3 mRNA CTD PMID:20003209 NCBI chr20:53,510,137...53,795,446
Ensembl chr20:53,510,184...53,790,165
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Isoproterenol results in increased expression of ASNS mRNA CTD PMID:21335049 PMID:21823215 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Asph aspartate-beta-hydroxylase decreases expression ISO Isoproterenol results in decreased expression of ASPH mRNA CTD PMID:20003209 NCBI chr 5:22,601,581...22,814,107
Ensembl chr 5:22,603,486...22,813,876
JBrowse link
G Aspn asporin increases expression ISO Isoproterenol results in increased expression of ASPN mRNA CTD PMID:20003209 NCBI chr17:15,079,910...15,104,369
Ensembl chr17:15,080,639...15,104,041
JBrowse link
G Atad2 ATPase family, AAA domain containing 2 increases expression ISO Isoproterenol results in increased expression of ATAD2 mRNA CTD PMID:20003209 NCBI chr 7:89,634,123...89,676,738
Ensembl chr 7:89,634,123...89,676,738
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions
increases phosphorylation
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased phosphorylation of ATF2 protein] CTD PMID:18089841 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Atf3 activating transcription factor 3 increases expression
multiple interactions
ISO
EXP
Isoproterenol results in increased expression of ATF3 mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of ATF3 protein]
CTD PMID:21823215 PMID:25136830 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atp10d ATPase phospholipid transporting 10D (putative) increases expression ISO Isoproterenol results in increased expression of ATP10D mRNA CTD PMID:20003209 NCBI chr14:35,911,728...36,012,549
Ensembl chr14:35,912,141...36,012,564
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions
decreases expression
EXP astragaloside A inhibits the reaction [Isoproterenol results in decreased expression of and results in decreased activity of ATP2A2 protein]; astragaloside A inhibits the reaction [Isoproterenol results in decreased expression of ATP2A2 mRNA]; candesartan inhibits the reaction [Isoproterenol results in decreased expression of ATP2A2 protein]; Isoproterenol results in decreased expression of and results in decreased activity of ATP2A2 protein
Isoproterenol results in decreased expression of ATP2A2 mRNA; Isoproterenol results in decreased expression of ATP2A2 protein
CTD PMID:16723803 PMID:17509559 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha multiple interactions
decreases expression
EXP
ISO
[Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP5F1A mRNA
Isoproterenol results in decreased expression of ATP5F1A mRNA
CTD PMID:20003209 PMID:30303030 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP5F1D mRNA CTD PMID:30303030 NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929
JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP5MC1 mRNA CTD PMID:30303030 NCBI chr10:81,024,056...81,026,780
Ensembl chr10:81,023,925...81,027,124
Ensembl chr10:81,023,925...81,027,124
JBrowse link
G Atp5me ATP synthase membrane subunit e multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in increased expression of ATP5ME mRNA CTD PMID:30303030 NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in increased expression of ATP5PD mRNA CTD PMID:30303030 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP5PO mRNA CTD PMID:30303030 NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592
JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP6AP2 mRNA CTD PMID:30303030 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918
JBrowse link
G Atp6v1e1 ATPase H+ transporting V1 subunit E1 decreases expression ISO Isoproterenol results in decreased expression of ATP6V1E1 mRNA CTD PMID:20003209 NCBI chr 4:154,022,358...154,044,486
Ensembl chr 4:154,022,358...154,044,584
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 increases expression ISO Isoproterenol results in increased expression of ATP8B1 mRNA CTD PMID:20003209 NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396
JBrowse link
G Atxn10 ataxin 10 increases expression ISO Isoproterenol results in increased expression of ATXN10 mRNA CTD PMID:20003209 NCBI chr 7:116,441,768...116,565,093
Ensembl chr 7:116,441,613...116,565,087
JBrowse link
G Auts2 activator of transcription and developmental regulator AUTS2 decreases expression ISO Isoproterenol results in decreased expression of AUTS2 mRNA CTD PMID:20003209 NCBI chr12:24,104,187...25,194,123
Ensembl chr12:24,104,192...25,194,416
JBrowse link
G Azi2 5-azacytidine induced 2 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of AZI2 mRNA CTD PMID:30303030 NCBI chr 8:117,773,248...117,797,844
Ensembl chr 8:117,773,279...117,797,847
JBrowse link
G Bag1 BAG cochaperone 1 decreases expression ISO Isoproterenol results in decreased expression of BAG1 mRNA CTD PMID:21335049 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
JBrowse link
G Bag4 BAG cochaperone 4 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of BAG4 mRNA CTD PMID:30303030 NCBI chr16:66,288,678...66,305,893
Ensembl chr16:66,288,678...66,308,663
JBrowse link
G Bak1 BCL2-antagonist/killer 1 decreases expression ISO Isoproterenol results in decreased expression of BAK1 mRNA CTD PMID:24286936 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
decreases expression
multiple interactions
ISO
EXP
Isoproterenol results in increased expression of BAX protein
Isoproterenol results in increased expression of BAX mRNA; Isoproterenol results in increased expression of BAX protein
Isoproterenol results in decreased expression of BAX mRNA
2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; [Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of BAX protein; [Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein; Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX mRNA]; Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX protein]; anethole inhibits the reaction [Isoproterenol results in increased expression of BAX mRNA]; Apigenin inhibits the reaction [Isoproterenol results in increased expression of BAX protein]; erdosteine inhibits the reaction [Isoproterenol results in increased expression of BAX protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; Plant Extracts inhibits the reaction [[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of BAX protein]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX mRNA]]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX protein]]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased expression of BAX protein]; punicalagin inhibits the reaction [Isoproterenol results in increased expression of BAX protein]; Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of BAX mRNA]; Tretinoin inhibits the reaction [Isoproterenol results in increased expression of BAX mRNA]
CTD PMID:15052282 PMID:16116328 PMID:17961425 PMID:24286936 PMID:24954035 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 increases expression EXP Isoproterenol results in increased expression of BCAT1 mRNA CTD PMID:20211217 PMID:23558518 PMID:24286936 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
increases expression
multiple interactions
ISO
EXP
Isoproterenol results in decreased expression of BCL2 protein
Isoproterenol results in decreased expression of BCL2 mRNA; Isoproterenol results in decreased expression of BCL2 protein
Isoproterenol results in increased expression of BCL2 mRNA
2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; [Acrolein results in increased susceptibility to Isoproterenol] which results in decreased expression of BCL2 protein; [erdosteine co-treated with Isoproterenol] affects the expression of BCL2 protein; [Isoproterenol co-treated with POSTN protein] results in increased expression of BCL2 mRNA; [Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein; Acrolein promotes the reaction [Isoproterenol results in decreased expression of BCL2 mRNA]; anethole inhibits the reaction [Isoproterenol results in increased expression of BCL2 mRNA]; Apigenin inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein]; echinocystic acid affects the reaction [Isoproterenol affects the expression of BCL2 mRNA]; Enalapril inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; Hesperidin inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein]; Plant Extracts inhibits the reaction [[Acrolein results in increased susceptibility to Isoproterenol] which results in decreased expression of BCL2 protein]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in decreased expression of BCL2 mRNA]]; protocatechuic acid inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein]; punicalagin inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein]
CTD PMID:11218852 PMID:12791704 PMID:15052282 PMID:19573579 PMID:24954035 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
multiple interactions
decreases expression
ISO
EXP
Isoproterenol results in increased expression of BCL2L1 mRNA
Apigenin inhibits the reaction [Isoproterenol results in decreased expression of BCL2L1 protein]; CGP 20712A inhibits the reaction [Isoproterenol results in increased expression of BCL2L1 protein]; geraniol inhibits the reaction [Isoproterenol results in decreased expression of BCL2L1 mRNA]; Metoprolol inhibits the reaction [Isoproterenol results in increased expression of BCL2L1 protein]; Perindopril inhibits the reaction [Isoproterenol results in increased expression of BCL2L1 mRNA alternative form]; Thymol inhibits the reaction [Isoproterenol results in decreased expression of BCL2L1 mRNA]
Isoproterenol results in increased expression of BCL2L1 mRNA alternative form; Isoproterenol results in increased expression of BCL2L1 protein; Isoproterenol results in increased expression of BCL2L1 protein alternative form
Isoproterenol results in decreased expression of BCL2L1 mRNA; Isoproterenol results in decreased expression of BCL2L1 protein
CTD PMID:12738230 PMID:16116328 PMID:20003209 PMID:24286936 PMID:26996544 More... NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression ISO
EXP
Isoproterenol results in increased expression of BCL2L11 protein
Isoproterenol results in increased expression of BCL2L11 mRNA
CTD PMID:14996839 PMID:24286936 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 increases expression ISO Isoproterenol results in increased expression of BDH1 mRNA CTD PMID:20003209 NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671
JBrowse link
G Bicd1 BICD cargo adaptor 1 increases expression ISO Isoproterenol results in increased expression of BICD1 mRNA CTD PMID:20003209 NCBI chr 4:182,479,071...182,631,504
Ensembl chr 4:182,479,071...182,627,434
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of BIRC2 mRNA CTD PMID:30303030 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 increases expression ISO Isoproterenol results in increased expression of BMAL1 mRNA CTD PMID:20003209 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Bmf Bcl2 modifying factor increases expression EXP Isoproterenol results in increased expression of BMF mRNA CTD PMID:24286936 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Bmp10 bone morphogenetic protein 10 multiple interactions
decreases response to substance
ISO BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; STAT3 protein affects the reaction [BMP10 protein results in decreased susceptibility to Isoproterenol]
BMP10 protein inhibits the reaction [Isoproterenol results in increased cleavage of PARP1 protein]; BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of COL1A1 protein]; BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]; STAT3 protein affects the reaction [BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]]
CTD PMID:31712309 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627
JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression EXP isoprenaline increases expression of mRNA in neonatal rat cardiomyocytes RGD PMID:26873969 RGD:11526363 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression EXP isoprenaline increases expression of mRNA in neonatal rat cardiomyocytes RGD PMID:26873969 RGD:11526363 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Bmp7 bone morphogenetic protein 7 increases expression EXP isoprenaline increases expression of mRNA in neonatal rat cardiomyocytes RGD PMID:26873969 RGD:11526363 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
JBrowse link
G Bnip1 BCL2 interacting protein 1 increases expression ISO Isoproterenol results in increased expression of BNIP1 protein CTD PMID:15052282 NCBI chr10:16,386,876...16,399,124
Ensembl chr10:16,386,841...16,399,157
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression ISO Isoproterenol results in increased expression of BNIP3 mRNA CTD PMID:20003209 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bok BCL2 family apoptosis regulator BOK decreases expression ISO Isoproterenol results in decreased expression of BOK mRNA CTD PMID:21335049 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Brd4 bromodomain containing 4 decreases expression
multiple interactions
increases expression
ISO Isoproterenol results in decreased expression of BRD4 mRNA
bellidifolin inhibits the reaction [Isoproterenol results in increased expression of BRD4 mRNA]; bellidifolin inhibits the reaction [Isoproterenol results in increased expression of BRD4 protein]
Isoproterenol results in increased expression of BRD4 mRNA; Isoproterenol results in increased expression of BRD4 protein
CTD PMID:20003209 PMID:37528096 NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539
JBrowse link
G Brwd1 bromodomain and WD repeat domain containing 1 increases expression ISO Isoproterenol results in increased expression of BRWD1 mRNA CTD PMID:20003209 NCBI chr11:35,286,364...35,378,768
Ensembl chr11:35,288,313...35,378,768
JBrowse link
G Bsdc1 BSD domain containing 1 increases expression ISO Isoproterenol results in increased expression of BSDC1 mRNA CTD PMID:20003209 NCBI chr 5:141,798,918...141,827,091
Ensembl chr 5:141,798,981...141,827,092
JBrowse link
G C3 complement C3 increases expression
decreases expression
multiple interactions
ISO
EXP
Isoproterenol results in increased expression of C3 mRNA
Isoproterenol results in increased expression of C3 mRNA; Isoproterenol results in increased expression of C3 protein
Isoproterenol results in decreased expression of C3 mRNA
Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of C3 protein]; pifithrin inhibits the reaction [Isoproterenol results in increased expression of C3 protein]; S100A9 protein affects the reaction [Isoproterenol results in increased expression of C3 protein]
CTD PMID:20003209 PMID:24286936 PMID:32924446 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G C4b complement C4B increases expression ISO Isoproterenol results in increased expression of C4B mRNA CTD PMID:20003209 NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681
JBrowse link
G C5 complement C5 increases expression
multiple interactions
EXP Isoproterenol results in increased expression of C5 protein
Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of C5 protein]; pifithrin inhibits the reaction [Isoproterenol results in increased expression of C5 protein]; S100A9 protein affects the reaction [Isoproterenol results in increased expression of C5 protein]
CTD PMID:32924446 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
JBrowse link
G C9 complement C9 increases expression EXP Isoproterenol results in increased expression of C9 mRNA CTD PMID:24286936 NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C increases expression EXP Isoproterenol results in increased expression of CACNA1C mRNA CTD PMID:17526999 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Cadm4 cell adhesion molecule 4 decreases expression ISO Isoproterenol results in decreased expression of CADM4 mRNA CTD PMID:20003209 NCBI chr 1:80,075,163...80,097,423
Ensembl chr 1:80,075,202...80,097,423
JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions EXP CALCA protein inhibits the reaction [Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]] CTD PMID:17306419 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Calcrl calcitonin receptor like receptor multiple interactions
increases expression
EXP [Phenylephrine co-treated with Isoproterenol] results in increased expression of CALCRL mRNA
Isoproterenol results in increased expression of CALCRL mRNA; Isoproterenol results in increased expression of CALCRL protein
CTD PMID:16987513 PMID:17250927 PMID:17306419 NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910
JBrowse link
G Calm3 calmodulin 3 decreases expression ISO Isoproterenol results in decreased expression of CALM3 mRNA CTD PMID:20003209 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
G Calr calreticulin increases expression ISO Isoproterenol results in increased expression of CALR mRNA CTD PMID:21823215 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Calr3 calreticulin 3 increases expression ISO Isoproterenol results in increased expression of CALR3 mRNA CTD PMID:20003209 NCBI chr16:17,396,064...17,423,166
Ensembl chr16:17,396,247...17,423,015
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta increases expression ISO Isoproterenol results in increased expression of CAMK2B mRNA CTD PMID:20003209 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta multiple interactions
increases expression
EXP [Carvedilol co-treated with aliskiren] inhibits the reaction [Isoproterenol results in increased expression of CAMK2D protein]; aliskiren inhibits the reaction [Isoproterenol results in increased expression of CAMK2D protein]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of CAMK2D protein] CTD PMID:26982530 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 decreases phosphorylation EXP Isoproterenol results in decreased phosphorylation of CAMKK2 protein CTD PMID:27491814 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279
JBrowse link
G Capn1 calpain 1 increases expression
multiple interactions
EXP Isoproterenol results in increased expression of CAPN1 mRNA
Quercetin inhibits the reaction [Isoproterenol results in increased expression of CAPN1 mRNA]
CTD PMID:27527349 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
JBrowse link
G Capn10 calpain 10 increases expression ISO Isoproterenol results in increased expression of CAPN10 mRNA CTD PMID:20003209 NCBI chr 9:93,498,132...93,510,494
Ensembl chr 9:93,498,478...93,510,494
JBrowse link
G Capn2 calpain 2 multiple interactions
increases expression
EXP Quercetin inhibits the reaction [Isoproterenol results in increased expression of CAPN2 mRNA] CTD PMID:27527349 NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969
JBrowse link
G Car4 carbonic anhydrase 4 increases expression ISO Isoproterenol results in increased expression of CAR4 mRNA CTD PMID:20003209 NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
JBrowse link
G Carmil1 capping protein regulator and myosin 1 linker 1 increases expression ISO Isoproterenol results in increased expression of CARMIL1 mRNA CTD PMID:20003209 NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326
JBrowse link
G Casp1 caspase 1 decreases expression
increases expression
ISO Isoproterenol results in decreased expression of CASP1 mRNA
Isoproterenol results in increased expression of CASP1 mRNA
CTD PMID:24286936 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp2 caspase 2 decreases expression
increases expression
EXP Isoproterenol results in decreased expression of CASP2 mRNA
Isoproterenol results in increased expression of CASP2 mRNA
CTD PMID:24286936 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
increases cleavage
ISO
EXP
Acetylcysteine inhibits the reaction [Isoproterenol results in increased activity of and results in increased cleavage of CASP3 protein]; BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Isoproterenol results in increased activity of and results in increased cleavage of CASP3 protein
BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Isoproterenol inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]; RAPGEF3 mutant form inhibits the reaction [Isoproterenol inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]]; STAT3 protein affects the reaction [BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]]
Isoproterenol results in increased expression of CASP3 mRNA; Isoproterenol results in increased expression of CASP3 protein
[Carvedilol co-treated with aliskiren] inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; [erdosteine co-treated with Isoproterenol] affects the expression of CASP3 protein; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; aliskiren inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; anethole inhibits the reaction [Isoproterenol results in increased cleavage of CASP3 protein]; Apigenin inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; benidipine inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; caryophyllene inhibits the reaction [Isoproterenol results in increased expression of CASP3 mRNA]; Enalapril inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Glyburide promotes the reaction [Isoproterenol results in increased activity of CASP3 protein]; Hesperidin inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; pifithrin inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Progesterone inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein]; punicalagin inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased activity of CASP3 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein]; S100A9 protein affects the reaction [Isoproterenol results in increased expression of CASP3 protein]; sodium thiosulfate inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein]; Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of CASP3 mRNA]
CTD PMID:11218852 PMID:17136323 PMID:17961425 PMID:20726854 PMID:21745194 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp6 caspase 6 decreases expression ISO Isoproterenol results in decreased expression of CASP6 mRNA CTD PMID:21335049 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp7 caspase 7 multiple interactions
decreases expression
ISO
EXP
Acetylcysteine inhibits the reaction [Isoproterenol results in increased activity of and results in increased cleavage of CASP7 protein]; Isoproterenol results in increased activity of and results in increased cleavage of CASP7 protein
Isoproterenol results in decreased expression of CASP7 mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of CASP7 mRNA
CTD PMID:17136323 PMID:24286936 PMID:30303030 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 increases expression
multiple interactions
EXP Isoproterenol results in increased expression of CASP8 mRNA; Isoproterenol results in increased expression of CASP8 protein
Apigenin inhibits the reaction [Isoproterenol results in increased expression of CASP8 protein]; caryophyllene inhibits the reaction [Isoproterenol results in increased expression of CASP8 mRNA]; Thymol inhibits the reaction [Isoproterenol results in increased expression of CASP8 mRNA]; Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of CASP8 mRNA]
CTD PMID:25794854 PMID:26996544 PMID:30152906 PMID:34816538 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions
increases activity
increases cleavage
EXP Isoproterenol results in increased expression of CASP9 mRNA; Isoproterenol results in increased expression of CASP9 protein
anethole inhibits the reaction [Isoproterenol results in increased cleavage of CASP9 protein]; Apigenin inhibits the reaction [Isoproterenol results in increased expression of CASP9 protein]; caryophyllene inhibits the reaction [Isoproterenol results in increased expression of CASP9 mRNA]; sodium thiosulfate inhibits the reaction [Isoproterenol results in increased activity of CASP9 protein]; Thymol inhibits the reaction [Isoproterenol results in increased expression of CASP9 mRNA]; Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of CASP9 mRNA]
CTD PMID:24286936 PMID:25794854 PMID:26996544 PMID:30152906 PMID:32865837 More... NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase decreases expression
increases expression
increases activity
multiple interactions
decreases activity
ISO
EXP
Isoproterenol results in decreased expression of CAT protein
Isoproterenol results in increased expression of CAT mRNA
Isoproterenol results in increased activity of CAT protein
Isoproterenol results in decreased expression of CAT mRNA; Isoproterenol results in decreased expression of CAT protein
5-Methoxypsoralen inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; [Rosuvastatin Calcium co-treated with Isoproterenol] inhibits the reaction [Interleukin-6 results in increased expression of CAT protein]; [Streptozocin co-treated with Isoproterenol] affects the activity of CAT protein; anethole inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Apigenin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Atenolol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Atenolol promotes the reaction [Quercetin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]]; benidipine inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Carvedilol inhibits the reaction [Isoproterenol results in decreased expression of and results in decreased activity of CAT protein]; caryophyllene inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Desmodium gangeticum extract inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; dicarbine inhibits the reaction [Isoproterenol results in increased activity of CAT protein]; Enalapril inhibits the reaction [Isoproterenol results in decreased expression of CAT protein]; erdosteine inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; ferruginol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Gallic Acid inhibits the reaction [Isoproterenol results in decreased expression of CAT protein]; geraniol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; geraniol inhibits the reaction [Isoproterenol results in decreased expression of CAT mRNA]; Glyburide promotes the reaction [Isoproterenol results in decreased activity of CAT protein]; Hesperidin inhibits the reaction [Isoproterenol results in decreased expression of CAT protein]; imetit inhibits the reaction [Isoproterenol results in decreased expression of and results in decreased activity of CAT protein]; Isoproterenol results in decreased expression of and results in decreased activity of CAT protein; mangiferin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; punicalagin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in decreased activity of CAT protein]]; pyrvinium inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Quercetin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Quercetin promotes the reaction [Atenolol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]]; Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Thymol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Tretinoin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Vincristine inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Vincristine inhibits the reaction [Isoproterenol results in decreased expression of CAT protein]
CTD PMID:1840475 PMID:12708743 PMID:15740881 PMID:16584858 PMID:16697266 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 multiple interactions ISO CAV1 protein promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein] CTD PMID:18820136 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cav3 caveolin 3 affects localization EXP Isoproterenol affects the localization of CAV3 protein CTD PMID:19299911 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
JBrowse link
G Cblb Cbl proto-oncogene B increases expression ISO Isoproterenol results in increased expression of CBLB mRNA CTD PMID:20003209 NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839
JBrowse link
G Ccdc80 coiled-coil domain containing 80 increases expression ISO Isoproterenol results in increased expression of CCDC80 mRNA CTD PMID:20003209 NCBI chr11:55,685,165...55,718,827
Ensembl chr11:55,685,872...55,719,137
JBrowse link
G Ccdc85a coiled-coil domain containing 85A increases expression ISO Isoproterenol results in increased expression of CCDC85A mRNA CTD PMID:20003209 NCBI chr14:102,126,574...102,359,207
Ensembl chr14:102,129,029...102,359,058
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 decreases secretion ISO Isoproterenol results in decreased secretion of CCL17 protein CTD PMID:12871855 NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Isoproterenol results in increased expression of CCL2 mRNA CTD PMID:21823215 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
decreases expression
increases expression
ISO Isoproterenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CCL3 protein]
Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein]
Isoproterenol results in decreased expression of CCL3 mRNA
Isoproterenol results in increased expression of CCL3 protein
CTD PMID:9863660 PMID:12538206 PMID:21335049 PMID:24286936 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression
decreases expression
EXP
ISO
Isoproterenol results in increased expression of CCL7 mRNA
Isoproterenol results in decreased expression of CCL7 mRNA
CTD PMID:20211217 PMID:24286936 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccl9 C-C motif chemokine ligand 9 increases expression ISO Isoproterenol results in increased expression of CCL6 mRNA CTD PMID:20003209 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression
decreases expression
multiple interactions
ISO
EXP
Isoproterenol results in increased expression of CCN2 mRNA
Isoproterenol results in decreased expression of CCN2 mRNA
Quercetin inhibits the reaction [Isoproterenol results in increased expression of CCN2 mRNA]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of CCN2 protein]; Rutin inhibits the reaction [Isoproterenol results in increased expression of CCN2 mRNA]; Rutin inhibits the reaction [Isoproterenol results in increased expression of CCN2 protein]
Isoproterenol results in increased expression of CCN2 mRNA; Isoproterenol results in increased expression of CCN2 protein
CTD PMID:20003209 PMID:24117263 PMID:24286936 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccnd1 cyclin D1 decreases expression
increases expression
ISO Isoproterenol results in decreased expression of CCND1 mRNA
Isoproterenol results in increased expression of CCND1 mRNA
CTD PMID:20003209 PMID:21335049 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd3 cyclin D3 increases expression ISO Isoproterenol results in increased expression of CCND3 mRNA CTD PMID:20003209 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccng2 cyclin G2 multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of CCNG2 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 increases expression EXP Isoproterenol results in increased expression of CCR1 mRNA CTD PMID:20211217 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Cd14 CD14 molecule increases expression EXP
ISO
Isoproterenol results in increased expression of CD14 mRNA CTD PMID:20003209 PMID:20211217 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd163 CD163 molecule increases expression ISO Isoproterenol results in increased expression of CD163 mRNA CTD PMID:20003209 NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878
JBrowse link
G Cd302 CD302 molecule increases expression ISO Isoproterenol results in increased expression of CD302 mRNA CTD PMID:20003209 NCBI chr 3:44,722,324...44,756,045
Ensembl chr 3:44,722,325...44,756,045
JBrowse link
G Cd36 CD36 molecule decreases expression EXP Isoproterenol results in decreased expression of CD36 protein CTD PMID:19826179 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd38 CD38 molecule multiple interactions ISO Isoproterenol promotes the reaction [CD38 gene mutant form results in increased activity of REN protein] CTD PMID:23343681 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986
JBrowse link
G Cd74 CD74 molecule decreases expression ISO Isoproterenol results in decreased expression of CD74 mRNA CTD PMID:20003209 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of CDC37 mRNA CTD PMID:30303030 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809
JBrowse link
G Cdc37l1 cell division cycle 37-like 1 increases expression ISO Isoproterenol results in increased expression of CDC37L1 mRNA CTD PMID:20003209 NCBI chr 1:226,705,019...226,733,994
Ensembl chr 1:226,705,003...226,761,175
JBrowse link
G Cdc42ep3 CDC42 effector protein 3 decreases expression ISO Isoproterenol results in decreased expression of CDC42EP3 mRNA CTD PMID:20003209 NCBI chr 6:15,710,894...15,731,366
Ensembl chr 6:15,708,730...15,732,721
JBrowse link
G Cdc42ep4 CDC42 effector protein 4 increases expression ISO Isoproterenol results in increased expression of CDC42EP4 mRNA CTD PMID:20003209 NCBI chr10:98,772,613...98,797,924
Ensembl chr10:98,772,495...98,797,695
JBrowse link
G Cdh11 cadherin 11 increases expression ISO Isoproterenol results in increased expression of CDH11 mRNA CTD PMID:20003209 NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272
JBrowse link
G Cdh13 cadherin 13 decreases expression ISO Isoproterenol results in decreased expression of CDH13 mRNA CTD PMID:20003209 NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459
JBrowse link
G Cdh2 cadherin 2 decreases expression ISO Isoproterenol results in decreased expression of CDH2 mRNA CTD PMID:21335049 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression
multiple interactions
ISO Isoproterenol results in increased expression of CDK1 mRNA; Isoproterenol results in increased expression of CDK1 protein
Atenolol inhibits the reaction [Isoproterenol results in increased expression of CDK1 mRNA]
CTD PMID:9593584 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of CDKN1A mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdo1 cysteine dioxygenase type 1 increases expression ISO Isoproterenol results in increased expression of CDO1 mRNA CTD PMID:20003209 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
JBrowse link
G Cds2 CDP-diacylglycerol synthase 2 increases expression ISO Isoproterenol results in increased expression of CDS2 mRNA CTD PMID:20003209 NCBI chr 3:119,514,963...119,553,555
Ensembl chr 3:119,515,000...119,553,541
JBrowse link
G Cdv3 carnitine deficiency-associated gene expressed in ventricle 3 increases expression ISO Isoproterenol results in increased expression of CDV3 mRNA CTD PMID:20003209 NCBI chr 8:103,934,006...103,947,173
Ensembl chr 8:103,933,996...103,947,192
JBrowse link
G Cdyl chromodomain Y-like increases expression ISO Isoproterenol results in increased expression of CDYL mRNA CTD PMID:20003209 NCBI chr17:28,982,009...29,204,345
Ensembl chr17:28,982,037...29,204,313
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO Isoproterenol results in increased expression of CEBPD mRNA CTD PMID:20003209 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma increases expression ISO Isoproterenol results in increased expression of CEBPG mRNA CTD PMID:20003209 NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569
JBrowse link
G Cenpa centromere protein A decreases expression ISO Isoproterenol results in decreased expression of CENPA mRNA CTD PMID:20003209 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
JBrowse link
G Cep192 centrosomal protein 192 increases expression ISO Isoproterenol results in increased expression of CEP192 mRNA CTD PMID:20003209 NCBI chr18:61,373,937...61,458,405
Ensembl chr18:61,332,158...61,458,379
JBrowse link
G Cfh complement factor H increases expression ISO Isoproterenol results in increased expression of CFH mRNA CTD PMID:20003209 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions
increases activity
ISO
EXP
[Isoproterenol co-treated with Adenosine] results in increased activity of CFTR protein; Baclofen promotes the reaction [Isoproterenol results in increased activity of CFTR protein]; Enkephalin, Leucine-2-Alanine promotes the reaction [Isoproterenol results in increased activity of CFTR protein]; Serotonin promotes the reaction [Isoproterenol results in increased activity of CFTR protein] CTD PMID:15020588 PMID:15039139 PMID:15151902 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Ch25h cholesterol 25-hydroxylase increases expression EXP Isoproterenol results in increased expression of CH25H mRNA CTD PMID:20211217 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO Isoproterenol results in increased expression of CHAC1 mRNA CTD PMID:20003209 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Chka choline kinase alpha increases expression ISO Isoproterenol results in increased expression of CHKA mRNA CTD PMID:20003209 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of CHUK mRNA CTD PMID:30303030 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Cidec cell death-inducing DFFA-like effector c multiple interactions ISO Isoproterenol results in increased expression of and results in decreased degradation of CIDEC protein; KT 5720 inhibits the reaction [Isoproterenol results in increased expression of CIDEC protein] CTD PMID:21097823 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
JBrowse link
G Cilp cartilage intermediate layer protein increases expression ISO Isoproterenol results in increased expression of CILP mRNA CTD PMID:20003209 NCBI chr 8:65,777,281...65,792,251
Ensembl chr 8:65,777,281...65,792,251
JBrowse link
G Cirbp cold inducible RNA binding protein decreases expression ISO Isoproterenol results in decreased expression of CIRBP mRNA CTD PMID:20003209 NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 increases expression ISO Isoproterenol results in increased expression of CITED2 mRNA CTD PMID:20003209 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 decreases expression ISO Isoproterenol results in decreased expression of CITED4 mRNA CTD PMID:20003209 NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:134,246,682...134,248,135
JBrowse link
G Ckb creatine kinase B multiple interactions
increases activity
EXP benidipine inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]]; Gallic Acid inhibits the reaction [Isoproterenol results in increased secretion of [CKM protein binds to CKB protein]]; imetit inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]]; Isoproterenol results in increased expression of [CKM protein binds to CKB protein]; Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]; Isoproterenol results in increased secretion of [CKM protein binds to CKB protein]; Lutein inhibits the reaction [Isoproterenol results in increased activity of CKB protein] CTD PMID:19146839 PMID:22391854 PMID:25269373 PMID:25496245 PMID:34435724 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Ckm creatine kinase, M-type multiple interactions
increases secretion
EXP [Carvedilol co-treated with aliskiren] inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of CKM protein]; aliskiren inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of CKM protein]; benidipine inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of CKM protein]; Gallic Acid inhibits the reaction [Isoproterenol results in increased secretion of [CKM protein binds to CKB protein]]; imetit inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]]; Isoproterenol results in increased expression of [CKM protein binds to CKB protein]; Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]; Isoproterenol results in increased expression of and results in increased secretion of CKM protein; Isoproterenol results in increased secretion of [CKM protein binds to CKB protein]; Quercetin inhibits the reaction [Isoproterenol results in increased secretion of CKM protein] CTD PMID:19146839 PMID:22391854 PMID:25269373 PMID:25496245 PMID:26982530 More... NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
JBrowse link
G Clca1 chloride channel accessory 1 increases expression ISO Isoproterenol results in increased expression of CLCA1 mRNA CTD PMID:20003209 NCBI chr 2:233,938,677...233,964,369
Ensembl chr 2:233,938,677...233,964,369
JBrowse link
G Clcn3 chloride voltage-gated channel 3 decreases expression ISO Isoproterenol results in decreased expression of CLCN3 mRNA CTD PMID:20003209 NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119
JBrowse link
G Clec1a C-type lectin domain family 1, member A increases expression ISO Isoproterenol results in increased expression of CLEC1A mRNA CTD PMID:20003209 NCBI chr 4:162,875,360...162,902,571
Ensembl chr 4:162,877,346...162,901,247
JBrowse link
G Clec4a C-type lectin domain family 4, member A increases expression ISO Isoproterenol results in increased expression of CLEC4N mRNA CTD PMID:20003209 NCBI chr 4:156,340,439...156,434,212
Ensembl chr 4:156,414,688...156,432,402
JBrowse link
G Clec4d C-type lectin domain family 4, member D increases expression ISO Isoproterenol results in increased expression of CLEC4D mRNA CTD PMID:20003209 NCBI chr 4:156,589,591...156,599,279
Ensembl chr 4:156,589,792...156,598,848
JBrowse link
G Clic5 chloride intracellular channel 5 increases expression ISO Isoproterenol results in increased expression of CLIC5 mRNA CTD PMID:20003209 NCBI chr 9:16,710,980...16,813,502
Ensembl chr 9:16,710,980...16,813,427
JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 increases expression ISO Isoproterenol results in increased expression of CLIP1 mRNA CTD PMID:20003209 NCBI chr12:32,910,932...33,017,891
Ensembl chr12:32,910,977...33,017,884
JBrowse link
G Clip4 CAP-GLY domain containing linker protein family, member 4 decreases expression ISO Isoproterenol results in decreased expression of CLIP4 mRNA CTD PMID:20003209 NCBI chr 6:23,616,280...23,697,625
NCBI chr 6:23,718,580...23,729,231
NCBI chr 6:23,597,729...23,601,000
Ensembl chr 6:23,616,281...23,677,874
JBrowse link
G Clpb ClpB family mitochondrial disaggregase decreases expression ISO Isoproterenol results in decreased expression of CLPB mRNA CTD PMID:20003209 NCBI chr 1:156,028,740...156,158,183
Ensembl chr 1:156,028,930...156,168,788
JBrowse link
G Clu clusterin increases expression ISO Isoproterenol results in increased expression of CLU mRNA; Isoproterenol results in increased expression of CLU protein CTD PMID:15052282 PMID:20003209 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cnksr1 connector enhancer of kinase suppressor of Ras 1 increases expression ISO Isoproterenol results in increased expression of CNKSR1 mRNA CTD PMID:20003209 NCBI chr 5:146,447,495...146,458,332
Ensembl chr 5:146,447,497...146,458,212
JBrowse link
G Cnksr3 Cnksr family member 3 increases expression ISO Isoproterenol results in increased expression of CNKSR3 mRNA CTD PMID:20003209 NCBI chr 1:43,499,273...43,591,630
Ensembl chr 1:43,499,487...43,591,635
JBrowse link
G Cobll1 cordon-bleu WH2 repeat protein-like 1 increases expression ISO Isoproterenol results in increased expression of COBLL1 mRNA CTD PMID:20003209 NCBI chr 3:49,753,260...49,915,168
Ensembl chr 3:49,753,262...49,915,194
JBrowse link
G Col15a1 collagen type XV alpha 1 chain decreases expression ISO Isoproterenol results in decreased expression of COL15A1 mRNA CTD PMID:20003209 NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression
increases expression
EXP
ISO
manidipine inhibits the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]
Isoproterenol results in increased expression of COL1A1 mRNA; Isoproterenol results in increased expression of COL1A1 protein
BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of COL1A1 protein]; celastrol methyl ester inhibits the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of COL1A1 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of COL1A1 protein]
isoprenaline increases expression of Col1a1 protein in blood serum
CTD
RGD
PMID:9559417 PMID:24945829 PMID:26692091 PMID:28526319 PMID:31009642 More... RGD:156430318 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions
decreases expression
ISO [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; DUSP1 protein inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; DUSP1 protein inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; JUNB protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; MAP2K1 protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; MAP2K1 protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; Propranolol inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; Propranolol inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; U 0126 inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; U 0126 inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]
Isoproterenol results in decreased expression of COL2A1 mRNA; Isoproterenol results in decreased expression of COL2A1 protein
CTD PMID:21177286 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions
increases expression
increases expression
EXP
ISO
AGT inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]; manidipine inhibits the reaction [Isoproterenol results in increased expression of COL3A1 mRNA]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased expression of COL3A1 mRNA]
Isoproterenol results in increased expression of COL3A1 mRNA; Isoproterenol results in increased expression of COL3A1 protein
BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of COL3A1 mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of COL3A1 mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]
isoprenaline increases expression of Col3a1 protein in blood serum
CTD
RGD
PMID:9559417 PMID:20409916 PMID:26692091 PMID:31009642 PMID:31712309 More... RGD:156430318 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Col5a1 collagen type V alpha 1 chain decreases expression ISO Isoproterenol results in decreased expression of COL5A1 mRNA CTD PMID:21335049 NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
JBrowse link
G Col5a2 collagen type V alpha 2 chain increases expression ISO Isoproterenol results in increased expression of COL5A2 mRNA CTD PMID:20003209 NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154
JBrowse link
G Comt catechol-O-methyltransferase increases methylation ISO COMT protein results in increased methylation of Isoproterenol CTD PMID:11160877 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Cops3 COP9 signalosome subunit 3 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of COPS3 mRNA CTD PMID:30303030 NCBI chr10:44,618,115...44,652,807
Ensembl chr10:44,618,115...44,641,597
JBrowse link
G Corin corin, serine peptidase increases expression ISO Isoproterenol results in increased expression of CORIN mRNA CTD PMID:20003209 NCBI chr14:35,680,601...35,910,703
Ensembl chr14:35,681,304...35,909,503
JBrowse link
G Cp ceruloplasmin multiple interactions
increases expression
decreases activity
EXP
ISO
allyl sulfide inhibits the reaction [Isoproterenol results in decreased activity of CP protein]
Isoproterenol results in increased expression of CP mRNA
Isoproterenol results in increased expression of CP protein
CTD PMID:1521861 PMID:15261977 PMID:20003209 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Cpne8 copine 8 increases expression ISO Isoproterenol results in increased expression of CPNE8 mRNA CTD PMID:20003209 NCBI chr 7:121,615,293...121,789,507
Ensembl chr 7:121,615,294...121,790,377
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 increases expression ISO Isoproterenol results in increased expression of CPS1 mRNA CTD PMID:21335049 NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of CPT1A mRNA CTD PMID:30303030 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B multiple interactions
decreases expression
EXP Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT1B mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT1B mRNA]] CTD PMID:25045214 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 decreases expression
multiple interactions
EXP Isoproterenol results in decreased expression of CPT2 mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of CPT2 mRNA; Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT2 mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT2 mRNA]]
CTD PMID:25045214 PMID:30303030 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
JBrowse link
G Crb1 crumbs cell polarity complex component 1 increases expression ISO Isoproterenol results in increased expression of CRB1 mRNA CTD PMID:20003209 NCBI chr13:50,801,484...50,989,261
Ensembl chr13:50,800,959...50,989,261
JBrowse link
G Crbn cereblon increases expression ISO Isoproterenol results in increased expression of CRBN mRNA CTD PMID:20003209 NCBI chr 4:139,701,154...139,719,949
Ensembl chr 4:139,701,094...139,719,938
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases phosphorylation
ISO
EXP
oxophenylarsine inhibits the reaction [Isoproterenol results in increased phosphorylation of CREB1 protein]
CREM protein inhibits the reaction [Isoproterenol results in increased activity of CREB1 protein]; swietenine inhibits the reaction [Isoproterenol results in increased phosphorylation of CREB1 protein]
CTD PMID:12791704 PMID:17141199 PMID:21745194 PMID:32686902 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crem cAMP responsive element modulator multiple interactions
affects localization
increases expression
EXP CREM protein inhibits the reaction [Isoproterenol results in increased activity of CREB1 protein]; CREM protein inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]; CREM protein inhibits the reaction [Isoproterenol results in increased expression of NPPA protein]
Isoproterenol affects the localization of CREM protein
Isoproterenol results in increased expression of CREM mRNA; Isoproterenol results in increased expression of CREM protein
CTD PMID:12791704 PMID:20211217 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
JBrowse link
G Crlf1 cytokine receptor-like factor 1 increases expression ISO Isoproterenol results in increased expression of CRLF1 mRNA CTD PMID:20003209 NCBI chr16:18,924,722...18,936,049
Ensembl chr16:18,924,722...18,935,997
JBrowse link
G Crp C-reactive protein increases expression
multiple interactions
EXP Isoproterenol results in increased expression of CRP protein
benidipine inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of CRP protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of CRP protein]; Isoproterenol results in increased expression of and results in increased secretion of CRP protein
CTD PMID:25269373 PMID:35608392 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cryab crystallin, alpha B multiple interactions EXP Isoproterenol inhibits the reaction [arsenite results in increased expression of CRYAB protein] CTD PMID:8769853 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Cryba4 crystallin, beta A4 decreases expression ISO Isoproterenol results in decreased expression of CRYBA4 mRNA CTD PMID:20003209 NCBI chr12:44,378,734...44,393,226
Ensembl chr12:44,378,737...44,393,221
JBrowse link
G Cs citrate synthase decreases activity EXP Isoproterenol results in decreased activity of CS protein CTD PMID:27491814 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
JBrowse link
G Csdc2 cold shock domain containing C2 increases expression ISO Isoproterenol results in increased expression of CSDC2 mRNA CTD PMID:20003209 NCBI chr 7:113,451,998...113,466,464
Ensembl chr 7:113,451,998...113,466,463
JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta increases expression ISO Isoproterenol results in increased expression of CSF2RB mRNA; Isoproterenol results in increased expression of CSF2RB2 mRNA CTD PMID:20003209 NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157
JBrowse link
G Csk C-terminal Src kinase multiple interactions ISO CSK protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP]; Isoproterenol inhibits the reaction [CSK protein promotes the reaction [Epinephrine results in increased abundance of Cyclic AMP]] CTD PMID:1699227 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
JBrowse link
G Ctf1 cardiotrophin 1 increases expression
multiple interactions
EXP Isoproterenol results in increased expression of CTF1 mRNA; Isoproterenol results in increased expression of CTF1 protein
Spironolactone inhibits the reaction [Isoproterenol results in increased expression of CTF1 mRNA]; Spironolactone inhibits the reaction [Isoproterenol results in increased expression of CTF1 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of CTF1 mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of CTF1 protein]
CTD PMID:23288202 NCBI chr 1:182,328,035...182,336,346
Ensembl chr 1:182,328,090...182,333,335
JBrowse link
G Cth cystathionine gamma-lyase multiple interactions EXP [Isoproterenol co-treated with Caffeine] results in decreased expression of CTH mRNA CTD PMID:29447158 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Cthrc1 collagen triple helix repeat containing 1 increases expression ISO Isoproterenol results in increased expression of CTHRC1 mRNA CTD PMID:20003209 NCBI chr 7:70,122,474...70,132,756
Ensembl chr 7:70,122,474...70,132,756
JBrowse link
G Ctnnal1 catenin alpha-like 1 increases expression ISO Isoproterenol results in increased expression of CTNNAL1 mRNA CTD PMID:20003209 NCBI chr 5:71,514,340...71,569,431
Ensembl chr 5:71,514,340...71,569,431
JBrowse link
G Ctnnb1 catenin beta 1 increases expression
multiple interactions
EXP Isoproterenol results in increased expression of CTNNB1 mRNA; Isoproterenol results in increased expression of CTNNB1 protein
[Glyburide co-treated with Isoproterenol] results in increased expression of CTNNB1 mRNA; Glyburide promotes the reaction [Isoproterenol results in increased expression of CTNNB1 protein]; pyrvinium inhibits the reaction [[Glyburide co-treated with Isoproterenol] results in increased expression of CTNNB1 mRNA]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of CTNNB1 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of CTNNB1 mRNA]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of CTNNB1 protein]
CTD PMID:35305975 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 decreases expression ISO Isoproterenol results in decreased expression of CTNNBIP1 mRNA CTD PMID:20003209 NCBI chr 5:159,961,961...160,010,942
Ensembl chr 5:159,961,928...160,010,939
JBrowse link
G Ctps2 CTP synthase 2 increases expression ISO Isoproterenol results in increased expression of CTPS2 mRNA CTD PMID:20003209 NCBI chr  X:31,645,873...31,786,733
Ensembl chr  X:31,645,873...31,786,733
JBrowse link
G Ctsb cathepsin B multiple interactions
decreases activity
decreases expression
increases activity
EXP
ISO
caffeic acid inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]; Curcumin inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]; epigallocatechin gallate inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]; naringin inhibits the reaction [Isoproterenol results in decreased activity of CTSB protein]; naringin inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]; Phytic Acid inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]
Isoproterenol results in decreased expression of CTSB mRNA
CTD PMID:2015110 PMID:8534267 PMID:17188415 PMID:18294627 PMID:20391626 More... NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsd cathepsin D multiple interactions
increases expression
decreases activity
increases activity
affects activity
EXP [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein]; [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; alliin affects the reaction [Isoproterenol affects the activity of CTSD protein]; caffeic acid inhibits the reaction [Isoproterenol affects the activity of CTSD protein]; Curcumin inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein]; Curcumin inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; epigallocatechin gallate inhibits the reaction [Isoproterenol affects the activity of CTSD protein]; mangiferin inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein]; Methylprednisolone inhibits the reaction [Isoproterenol results in increased expression of CTSD mRNA]; naringin inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; Phytic Acid inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; Plant Extracts inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; S-allylcysteine inhibits the reaction [Isoproterenol results in increased expression of CTSD mRNA]
Isoproterenol results in increased expression of CTSD mRNA; Isoproterenol results in increased expression of CTSD protein
CTD PMID:894732 PMID:2015110 PMID:8534267 PMID:11829124 PMID:14499179 More... NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Ctsl cathepsin L increases expression ISO Isoproterenol results in increased expression of CTSL mRNA CTD PMID:20003209 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Cul1 cullin 1 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of CUL1 mRNA CTD PMID:30303030 NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980
JBrowse link
G Cul4b cullin 4B increases expression ISO Isoproterenol results in increased expression of CUL4B mRNA CTD PMID:20003209 NCBI chr  X:117,287,481...117,326,688
Ensembl chr  X:117,287,484...117,326,688
JBrowse link
G Cux2 cut-like homeobox 2 decreases expression ISO Isoproterenol results in decreased expression of CUX2 mRNA CTD PMID:20003209 NCBI chr12:34,507,723...34,707,581
Ensembl chr12:34,520,959...34,705,806
JBrowse link
G Cuzd1 CUB and zona pellucida-like domains 1 increases expression ISO Isoproterenol results in increased expression of CUZD1 mRNA CTD PMID:20003209 NCBI chr 1:186,089,422...186,130,536
Ensembl chr 1:186,089,423...186,102,546
JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 increases expression ISO Isoproterenol results in increased expression of CXCL13 mRNA CTD PMID:20003209 NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 decreases expression ISO Isoproterenol results in decreased expression of CXCL9 mRNA CTD PMID:20003209 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 increases activity ISO Isoproterenol results in increased activity of CXCR2 protein CTD PMID:15477226 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
JBrowse link
G Cxxc5 CXXC finger protein 5 decreases expression ISO Isoproterenol results in decreased expression of CXXC5 mRNA CTD PMID:20003209 NCBI chr18:27,427,591...27,458,579
Ensembl chr18:27,427,230...27,458,673
JBrowse link
G Cyba cytochrome b-245 alpha chain increases expression
multiple interactions
EXP Isoproterenol results in increased expression of CYBA mRNA
CPU0213 inhibits the reaction [Isoproterenol results in increased expression of CYBA mRNA]; pimagedine inhibits the reaction [Isoproterenol results in increased expression of CYBA mRNA]
CTD PMID:18594475 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cycs cytochrome c, somatic increases expression
multiple interactions
EXP Isoproterenol results in increased expression of CYCS protein
Apigenin inhibits the reaction [Isoproterenol results in increased expression of CYCS protein]
CTD PMID:30152906 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression
multiple interactions
increases expression
ISO
EXP
Isoproterenol results in decreased expression of CYP1A1 mRNA
Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A1 protein]; Propranolol inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A1 protein]]
Isoproterenol results in increased expression of CYP1A1 mRNA
CTD PMID:15627480 PMID:15710352 PMID:18725507 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO
EXP
Isoproterenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]; Propranolol inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]]
CTD PMID:15710352 PMID:18493746 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression EXP
ISO
Isoproterenol results in increased expression of CYP1B1 mRNA CTD PMID:18725507 PMID:20003209 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases expression ISO Isoproterenol results in decreased expression of CYP26B1 mRNA CTD PMID:20003209 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Isoproterenol results in increased expression of CYP2B10 mRNA CTD PMID:20003209 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases expression EXP Isoproterenol results in decreased expression of CYP2C11 mRNA CTD PMID:18725507 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects expression EXP Isoproterenol affects the expression of CYP2E1 mRNA CTD PMID:18725507 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 increases expression EXP Isoproterenol results in increased expression of CYP4A3 mRNA CTD PMID:18725507 NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 increases expression ISO Isoproterenol results in increased expression of CYSLTR1 mRNA CTD PMID:20003209 NCBI chr  X:71,661,421...71,690,012
Ensembl chr  X:71,663,821...71,690,121
JBrowse link
G Cyss cystatin S multiple interactions
increases expression
EXP Reserpine inhibits the reaction [Isoproterenol results in increased expression of CYSS mRNA] CTD PMID:9447264 NCBI chr 3:137,432,049...137,436,654
Ensembl chr 3:137,432,049...137,436,610
JBrowse link
G Dag1 dystroglycan 1 decreases expression EXP Isoproterenol results in decreased expression of DAG1 CTD PMID:18808529 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325
JBrowse link
G Dap death-associated protein multiple interactions
increases expression
EXP [Isoproterenol co-treated with POSTN protein] results in increased expression of DAP mRNA
Isoproterenol results in increased expression of DAP mRNA
CTD PMID:30303030 NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:82,199,280...82,251,752
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor decreases expression ISO Isoproterenol results in decreased expression of DBP mRNA CTD PMID:20003209 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
JBrowse link
G Dcakd dephospho-CoA kinase domain containing decreases expression ISO Isoproterenol results in decreased expression of DCAKD mRNA CTD PMID:20003209 NCBI chr10:87,957,738...87,989,002
Ensembl chr10:87,957,740...87,980,054
JBrowse link
G Dcn decorin increases expression ISO Isoproterenol results in increased expression of DCN mRNA CTD PMID:20003209 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Dct dopachrome tautomerase increases expression ISO Isoproterenol results in increased expression of DCT mRNA CTD PMID:20003209 NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836
JBrowse link
G Dctn5 dynactin subunit 5 increases expression ISO Isoproterenol results in increased expression of DCTN5 mRNA CTD PMID:21335049 NCBI chr 1:176,689,176...176,705,907
Ensembl chr 1:176,689,156...176,705,906
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO
EXP
Isoproterenol results in increased expression of DDIT3 mRNA
[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of DDIT3 protein; Acrolein promotes the reaction [Isoproterenol results in increased expression of DDIT3 mRNA]; Plant Extracts inhibits the reaction [[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of DDIT3 protein]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of DDIT3 mRNA]]
CTD PMID:21823215 PMID:29414845 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of DDIT4 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Ddost dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit increases expression ISO Isoproterenol results in increased expression of DDOST mRNA CTD PMID:21823215 NCBI chr 5:150,522,297...150,529,413
Ensembl chr 5:150,522,242...150,529,413
JBrowse link
G Defb1 defensin beta 1 decreases expression
increases expression
EXP Isoproterenol results in decreased expression of DEFB1 mRNA
Isoproterenol results in increased expression of DEFB1 mRNA
CTD PMID:24286936 NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604
JBrowse link
G Dennd4a DENN domain containing 4A increases expression ISO Isoproterenol results in increased expression of DENND4A mRNA CTD PMID:20003209 NCBI chr 8:65,322,920...65,436,331
Ensembl chr 8:65,322,941...65,436,330
JBrowse link
G Derl2 derlin 2 increases expression ISO Isoproterenol results in increased expression of DERL2 mRNA CTD PMID:21823215 NCBI chr10:55,727,764...55,739,442
Ensembl chr10:55,727,643...55,739,518
JBrowse link
G Derl3 derlin 3 decreases expression ISO Isoproterenol results in decreased expression of DERL3 mRNA CTD PMID:21823215 NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027
JBrowse link
G Des desmin decreases expression
multiple interactions
EXP Isoproterenol results in decreased expression of DES protein
Lutein inhibits the reaction [Isoproterenol results in decreased expression of DES protein]
CTD PMID:34435724 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
JBrowse link
G Dffb DNA fragmentation factor subunit beta increases expression ISO Isoproterenol results in increased expression of DFFB mRNA CTD PMID:20003209 NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO Isoproterenol results in decreased expression of DHCR24 mRNA CTD PMID:20003209 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 decreases expression ISO Isoproterenol results in decreased expression of DHRS3 mRNA CTD PMID:21335049 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
JBrowse link
G Dhrs7 dehydrogenase/reductase 7 decreases expression ISO Isoproterenol results in decreased expression of DHRS7 mRNA CTD PMID:20003209 PMID:21335049 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892
JBrowse link
G Dhrs7c dehydrogenase/reductase 7C decreases expression ISO Isoproterenol results in decreased expression of DHRS7C mRNA CTD PMID:20003209 NCBI chr10:52,495,262...52,513,338
Ensembl chr10:52,495,262...52,513,338
JBrowse link
G Diaph2 diaphanous-related formin 2 increases expression ISO Isoproterenol results in increased expression of DIAPH2 mRNA CTD PMID:20003209 NCBI chr  X:92,395,189...93,234,521
Ensembl chr  X:92,395,251...93,229,869
JBrowse link
G Dio2 iodothyronine deiodinase 2 increases expression
increases activity
ISO
EXP
Isoproterenol results in increased expression of DIO2 mRNA
Isoproterenol results in increased activity of DIO2 protein
CTD PMID:15345674 PMID:20003209 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
JBrowse link
G Dixdc1 DIX domain containing 1 increases expression ISO Isoproterenol results in increased expression of DIXDC1 mRNA CTD PMID:20003209 NCBI chr 8:51,007,835...51,081,191
Ensembl chr 8:51,007,838...51,081,090
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase decreases expression ISO Isoproterenol results in decreased expression of DLAT mRNA CTD PMID:21335049 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
JBrowse link
G Dmac2l distal membrane arm assembly component 2 like multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of DMAC2L mRNA CTD PMID:30303030 NCBI chr 6:88,205,580...88,223,934
Ensembl chr 6:88,205,700...88,223,933
JBrowse link
G Dmd dystrophin multiple interactions
decreases expression
ISO
EXP
DMD gene mutant form promotes the reaction [ITGB1 gene affects the susceptibility to Isoproterenol]
Isoproterenol results in decreased expression of DMD
CTD PMID:18340010 PMID:18808529 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207
JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 increases expression ISO Isoproterenol results in increased expression of DNAJB11 mRNA CTD PMID:21823215 NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Isoproterenol results in increased expression of DNAJB9 mRNA CTD PMID:21335049 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
JBrowse link
G Dnm1l dynamin 1-like increases phosphorylation EXP Isoproterenol results in increased phosphorylation of DNM1L protein CTD PMID:27491814 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression
increases expression
ISO
EXP
Isoproterenol results in decreased expression of DNMT3A mRNA
Isoproterenol results in increased expression of DNMT3A protein
CTD PMID:20003209 PMID:24945829 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta increases expression ISO Isoproterenol results in increased expression of DNMT3B mRNA CTD PMID:21335049 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Dnttip2 deoxynucleotidyltransferase, terminal, interacting protein 2 increases expression ISO Isoproterenol results in increased expression of DNTTIP2 mRNA CTD PMID:20003209 NCBI chr 2:210,374,321...210,386,366
Ensembl chr 2:210,374,289...210,385,581
JBrowse link
G Dock10 dedicator of cytokinesis 10 increases expression ISO Isoproterenol results in increased expression of DOCK10 mRNA CTD PMID:20003209 NCBI chr 9:81,843,599...82,101,540
Ensembl chr 9:81,843,604...82,101,525
JBrowse link
G Dock9 dedicator of cytokinesis 9 increases expression ISO Isoproterenol results in increased expression of DOCK9 mRNA CTD PMID:20003209 NCBI chr15:98,611,518...98,883,306
Ensembl chr15:98,618,084...98,883,153
JBrowse link
G Dpep1 dipeptidase 1 increases expression ISO Isoproterenol results in increased expression of DPEP1 mRNA CTD PMID:20003209 NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257
JBrowse link
G Dpp7 dipeptidylpeptidase 7 increases expression ISO Isoproterenol results in increased expression of DPP7 mRNA CTD PMID:20003209 NCBI chr 3:8,165,091...8,169,343
Ensembl chr 3:8,165,091...8,169,355
JBrowse link
G Dsg2 desmoglein 2 decreases expression ISO Isoproterenol results in decreased expression of DSG2 mRNA CTD PMID:20003209 NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156
JBrowse link
G Dtx4 deltex E3 ubiquitin ligase 4 increases expression ISO Isoproterenol results in increased expression of DTX4 mRNA CTD PMID:20003209 NCBI chr 1:209,457,719...209,545,163
Ensembl chr 1:209,460,735...209,492,818
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions ISO DUSP1 protein inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; DUSP1 protein inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; DUSP1 protein inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; DUSP1 protein inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein] CTD PMID:21177286 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression ISO Isoproterenol results in increased expression of DUSP4 mRNA CTD PMID:20003209 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
JBrowse link
G Dusp5 dual specificity phosphatase 5 decreases expression EXP isoprenaline decreases expression of Dusp5 mRNA and protein in cardiac muscle cells RGD PMID:27318893 RGD:156430318 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
JBrowse link
G Dusp8 dual specificity phosphatase 8 decreases expression ISO Isoproterenol results in decreased expression of DUSP8 mRNA CTD PMID:20003209 NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921
JBrowse link
G Dxo decapping exoribonuclease increases expression ISO Isoproterenol results in increased expression of DXO mRNA CTD PMID:21335049 NCBI chr20:3,993,322...3,995,484
Ensembl chr20:3,993,327...3,995,494
JBrowse link
G Ecm1 extracellular matrix protein 1 increases expression ISO Isoproterenol results in increased expression of ECM1 mRNA CTD PMID:20003209 NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression ISO Isoproterenol results in increased expression of EDEM1 mRNA CTD PMID:21335049 PMID:21823215 NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
JBrowse link
G Edn1 endothelin 1 multiple interactions
increases expression
increases activity
EXP Cyclosporine inhibits the reaction [Isoproterenol results in increased activity of EDN1 promoter]; Glyburide inhibits the reaction [natakalim inhibits the reaction [Isoproterenol results in increased expression of EDN1 mRNA]]; Glyburide inhibits the reaction [natakalim inhibits the reaction [Isoproterenol results in increased expression of EDN1 protein]]; N-(1-methylethyl)-1,1,2-trimethylpropylamine inhibits the reaction [Isoproterenol results in increased expression of EDN1 mRNA]; N-(1-methylethyl)-1,1,2-trimethylpropylamine inhibits the reaction [Isoproterenol results in increased expression of EDN1 protein]; natakalim inhibits the reaction [Isoproterenol results in increased expression of EDN1 mRNA]; natakalim inhibits the reaction [Isoproterenol results in increased expression of EDN1 protein]; Nifedipine inhibits the reaction [Isoproterenol results in increased activity of EDN1 promoter]
Isoproterenol results in increased expression of EDN1 mRNA; Isoproterenol results in increased expression of EDN1 protein
CTD PMID:9861301 PMID:11435416 PMID:27174236 PMID:27890915 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A increases expression
multiple interactions
ISO
EXP
Isoproterenol results in increased expression of EDNRA mRNA
CPU0213 inhibits the reaction [Isoproterenol results in increased expression of EDNRA mRNA]; CPU0213 inhibits the reaction [Isoproterenol results in increased expression of EDNRA protein]; natakalim inhibits the reaction [Isoproterenol results in increased expression of EDNRA protein]; pimagedine inhibits the reaction [Isoproterenol results in increased expression of EDNRA mRNA]
Isoproterenol results in increased expression of EDNRA mRNA; Isoproterenol results in increased expression of EDNRA protein
CTD PMID:18594475 PMID:20003209 PMID:20307649 PMID:27174236 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Ednrb endothelin receptor type B multiple interactions
increases expression
EXP CPU0213 inhibits the reaction [Isoproterenol results in increased expression of EDNRB mRNA]; natakalim inhibits the reaction [Isoproterenol results in increased expression of EDNRB protein]
Isoproterenol results in increased expression of EDNRB mRNA; Isoproterenol results in increased expression of EDNRB protein
CTD PMID:18594475 PMID:27174236 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
JBrowse link
G Eef1akmt1 EEF1A lysine methyltransferase 1 decreases expression ISO Isoproterenol results in decreased expression of EEF1AKMT1 mRNA CTD PMID:20003209 NCBI chr15:31,694,284...31,711,367
Ensembl chr15:31,694,292...31,711,336
JBrowse link
G Efhd2 EF-hand domain family, member D2 increases expression ISO Isoproterenol results in increased expression of EFHD2 mRNA CTD PMID:20003209 NCBI chr 5:154,160,945...154,176,980
Ensembl chr 5:154,160,946...154,176,980
JBrowse link
G Egfr epidermal growth factor receptor increases expression
multiple interactions
ISO Isoproterenol results in increased expression of EGFR mRNA
Isoproterenol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]
CTD PMID:18787115 PMID:20003209 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 multiple interactions
decreases expression
increases expression
ISO
EXP
EGR1 protein affects the reaction [[Isoproterenol co-treated with Phenylephrine] results in increased expression of SLC8A1 mRNA]; EGR1 protein affects the reaction [[Isoproterenol co-treated with Phenylephrine] results in increased expression of SLC8A1 protein]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of ACTA1 mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of JUN mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NAB2 mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NPPA mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of SP1 mRNA]
Isoproterenol results in decreased expression of EGR1 mRNA
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Isoproterenol results in increased expression of EGR1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of EGR1 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of EGR1 protein]
CTD PMID:10710348 PMID:15621046 PMID:20003209 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Eif1a eukaryotic translation initiation factor 1A increases expression ISO Isoproterenol results in increased expression of EIF1A mRNA CTD PMID:20003209 PMID:21335049 NCBI chr18:39,325,695...39,338,043
Ensembl chr18:39,325,202...39,338,696
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression ISO Isoproterenol results in increased expression of EIF2AK3 mRNA CTD PMID:21335049 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 decreases expression ISO Isoproterenol results in decreased expression of EIF4A2 mRNA CTD PMID:21335049 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E decreases expression ISO Isoproterenol results in decreased expression of EIF4E mRNA CTD PMID:20003209 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 increases expression ISO Isoproterenol results in increased expression of ELL2 mRNA CTD PMID:20003209 NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781
JBrowse link
G Eln elastin multiple interactions
increases expression
EXP [Isoproterenol co-treated with Hydralazine] results in increased expression of ELN protein
Isoproterenol results in increased expression of ELN protein
CTD PMID:3446201 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 increases expression ISO Isoproterenol results in increased expression of ELOVL1 mRNA CTD PMID:20003209 NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958
JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of ELP1 mRNA CTD PMID:30303030 NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762
JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression ISO Isoproterenol results in increased expression of ENC1 mRNA CTD PMID:20003209 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
JBrowse link
G Eno1 enolase 1 decreases expression ISO Isoproterenol results in decreased expression of ENO1 mRNA CTD PMID:20003209 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 decreases expression EXP Isoproterenol results in decreased expression of ENPP1 protein CTD PMID:21414308 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 increases expression ISO Isoproterenol results in increased expression of ENTPD1 mRNA CTD PMID:20003209 NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317
JBrowse link
G Eps8 EGFR pathway substrate 8, signaling adaptor increases expression ISO Isoproterenol results in increased expression of EPS8 mRNA CTD PMID:20003209 NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873
JBrowse link
G Ereg epiregulin increases expression ISO Isoproterenol results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
JBrowse link
G Erp29 endoplasmic reticulum protein 29 increases expression ISO Isoproterenol results in increased expression of ERP29 mRNA CTD PMID:21335049 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 increases expression ISO Isoproterenol results in increased expression of ERRFI1 mRNA CTD PMID:20003209 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Etf1 eukaryotic translation termination factor 1 increases expression ISO Isoproterenol results in increased expression of ETF1 mRNA CTD PMID:20003209 NCBI chr18:26,502,413...26,530,753
Ensembl chr18:26,504,080...26,530,810
JBrowse link
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit increases expression ISO Isoproterenol results in increased expression of EZH1 mRNA CTD PMID:20003209 NCBI chr10:86,126,023...86,162,001
Ensembl chr10:86,126,015...86,161,921
JBrowse link
G F13a1 coagulation factor XIII A1 chain increases expression ISO Isoproterenol results in increased expression of F13A1 mRNA CTD PMID:20003209 NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700
JBrowse link
G Fabp3 fatty acid binding protein 3 increases expression
decreases expression
ISO
EXP
Isoproterenol results in increased expression of FABP3 protein
Isoproterenol results in decreased expression of FABP3 protein
CTD PMID:19549929 PMID:19826179 PMID:19854236 PMID:22878004 NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718
JBrowse link
G Fabp5 fatty acid binding protein 5 increases expression ISO Isoproterenol results in increased expression of FABP5 mRNA CTD PMID:21335049 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
JBrowse link
G Fam110d family with sequence similarity 110, member D increases expression ISO Isoproterenol results in increased expression of FAM110D mRNA CTD PMID:20003209 NCBI chr 5:146,471,048...146,474,019
Ensembl chr 5:146,471,049...146,474,056
JBrowse link
G Fam117b family with sequence similarity 117, member B increases expression ISO Isoproterenol results in increased expression of FAM117B mRNA CTD PMID:20003209 NCBI chr 9:61,340,284...61,418,531
Ensembl chr 9:61,340,249...61,408,483
JBrowse link
G Farp1 FERM, ARH/RhoGEF and pleckstrin domain protein 1 increases expression ISO Isoproterenol results in increased expression of FARP1 mRNA CTD PMID:21335049 NCBI chr15:98,124,304...98,363,299
Ensembl chr15:98,182,329...98,363,299
JBrowse link
G Fas Fas cell surface death receptor increases expression
multiple interactions
ISO
EXP
Isoproterenol results in increased expression of FAS mRNA
Isoproterenol results in increased expression of FAS mRNA; Isoproterenol results in increased expression of FAS protein
Apigenin inhibits the reaction [Isoproterenol results in increased expression of FAS protein]; caryophyllene inhibits the reaction [Isoproterenol results in increased expression of FAS mRNA]; Thymol inhibits the reaction [Isoproterenol results in increased expression of FAS mRNA]; Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of FAS mRNA]
CTD PMID:11218852 PMID:20003209 PMID:24286936 PMID:25794854 PMID:26996544 More... NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand increases expression EXP Isoproterenol results in increased expression of FASLG protein CTD PMID:19001025 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fblim1 filamin binding LIM protein 1 decreases expression ISO Isoproterenol results in decreased expression of FBLIM1 mRNA CTD PMID:20003209 NCBI chr 5:153,883,945...153,915,524
Ensembl chr 5:153,883,960...153,913,757
JBrowse link
G Fbln2 fibulin 2 increases expression ISO Isoproterenol results in increased expression of FBLN2 mRNA CTD PMID:20003209 NCBI chr 4:123,704,289...123,763,857
Ensembl chr 4:123,704,373...123,763,948
JBrowse link
G Fbxl20 F-box and leucine-rich repeat protein 20 increases expression ISO Isoproterenol results in increased expression of FBXL20 mRNA CTD PMID:20003209 NCBI chr10:83,080,568...83,143,680
Ensembl chr10:83,086,551...83,144,162
JBrowse link
G Fbxo31 F-box protein 31 increases expression ISO Isoproterenol results in increased expression of FBXO31 mRNA CTD PMID:20003209 NCBI chr19:49,624,813...49,656,052
Ensembl chr19:49,627,686...49,656,010
JBrowse link
G Fbxo32 F-box protein 32 increases expression ISO Isoproterenol results in increased expression of FBXO32 mRNA CTD PMID:20003209 NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436
JBrowse link
G Fbxo9 f-box protein 9 decreases expression ISO Isoproterenol results in decreased expression of FBXO9 mRNA CTD PMID:21335049 NCBI chr 8:78,958,482...78,984,015
Ensembl chr 8:78,958,483...78,983,949
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 decreases expression ISO Isoproterenol results in decreased expression of FBXW7 mRNA CTD PMID:20003209 NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Fcgr2a Fc gamma receptor 2A increases expression ISO Isoproterenol results in increased expression of FCGR3 mRNA CTD PMID:20003209 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
G Fcgr2b Fc gamma receptor 2B increases expression EXP
ISO
Isoproterenol results in increased expression of FCGR2B mRNA CTD PMID:20003209 PMID:20211217 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778
JBrowse link
G Fcgr3a Fc gamma receptor 3A increases expression ISO Isoproterenol results in increased expression of FCGR4 mRNA CTD PMID:20003209 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921
JBrowse link
G Fen1 flap structure-specific endonuclease 1 increases expression ISO Isoproterenol results in increased expression of FEN1 mRNA CTD PMID:21335049 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003
JBrowse link
G Fetub fetuin B increases expression ISO Isoproterenol results in increased expression of FETUB mRNA CTD PMID:20003209 NCBI chr11:78,082,158...78,093,022
Ensembl chr11:78,082,156...78,095,135
JBrowse link
G Fgf16 fibroblast growth factor 16 decreases expression ISO Isoproterenol results in decreased expression of FGF16 mRNA CTD PMID:20003209 NCBI chr  X:70,816,658...70,828,028
Ensembl chr  X:70,817,433...70,878,717
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 increases expression ISO Isoproterenol results in increased expression of FGFR3 mRNA CTD PMID:20003209 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
G Fhl1 four and a half LIM domains 1 decreases expression
increases expression
ISO
EXP
Isoproterenol results in decreased expression of FHL1 mRNA
Isoproterenol results in increased expression of FHL1 mRNA
CTD PMID:20211217 PMID:23558518 PMID:24286936 NCBI chr  X:134,555,399...134,614,930
Ensembl chr  X:134,555,479...134,614,928
JBrowse link
G Fis1 fission, mitochondrial 1 increases expression EXP Isoproterenol results in increased expression of FIS1 protein CTD PMID:27491814 NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B multiple interactions
decreases expression
EXP 1-(methanesulfonamido-1-naphthyloxy)-2-(N-(4-methane sulfonamidophenethyl)-N-acetamido)ethane inhibits the reaction [Isoproterenol results in decreased expression of FKBP1B mRNA]; 1-(methanesulfonamido-1-naphthyloxy)-2-(N-(4-methane sulfonamidophenethyl)-N-acetamido)ethane inhibits the reaction [Isoproterenol results in decreased expression of FKBP1B protein]; dofetilide inhibits the reaction [Isoproterenol results in decreased expression of FKBP1B mRNA]; dofetilide inhibits the reaction [Isoproterenol results in decreased expression of FKBP1B protein]
Isoproterenol results in decreased expression of FKBP1B mRNA; Isoproterenol results in decreased expression of FKBP1B protein
CTD PMID:20723002 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 decreases expression ISO Isoproterenol results in decreased expression of FKBP4 mRNA CTD PMID:20003209 NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 increases expression ISO Isoproterenol results in increased expression of FKBP5 mRNA CTD PMID:20003209 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 increases expression ISO Isoproterenol results in increased expression of FLT1 mRNA CTD PMID:20003209 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 increases expression ISO Isoproterenol results in increased expression of FMO1 mRNA CTD PMID:20003209 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 increases expression ISO Isoproterenol results in increased expression of FMO2 mRNA CTD PMID:20003209 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
JBrowse link
G Fn1 fibronectin 1 decreases expression
increases expression
multiple interactions
ISO
EXP
Isoproterenol results in decreased expression of FN1 protein
Isoproterenol results in increased expression of FN1 mRNA
Glyburide promotes the reaction [Isoproterenol results in increased expression of FN1 protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of FN1 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of FN1 protein]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of FN1 protein]; Rutin inhibits the reaction [Isoproterenol results in increased expression of FN1 protein]
CTD PMID:11821714 PMID:20003209 PMID:24117263 PMID:35305975 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO
EXP
[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]; [Phenylephrine co-treated with Isoproterenol] results in increased expression of FOS mRNA; Doxycycline inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]; U 0126 inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]
CREM protein inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]; Isoproterenol promotes the reaction [JUN protein binds to FOS protein]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of FOS]
Isoproterenol results in increased expression of FOS; Isoproterenol results in increased expression of FOS mRNA
Isoproterenol results in increased expression of FOS mRNA; Isoproterenol results in increased expression of FOS protein
CTD PMID:7544033 PMID:7905536 PMID:10710348 PMID:12791704 PMID:14764439 More... NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression EXP Isoproterenol results in increased expression of FOSB CTD PMID:7905536 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression
multiple interactions
EXP
ISO
Isoproterenol results in increased expression of FOSL1 mRNA
Isoproterenol results in increased expression of FOSL1 mRNA; Isoproterenol results in increased expression of FOSL1 protein
[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of FOSL1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of FOSL1 mRNA]; U 0126 inhibits the reaction [Isoproterenol results in increased expression of FOSL1 mRNA]
CTD PMID:20211217 PMID:21177286 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression
multiple interactions
ISO Isoproterenol results in increased expression of FOSL2 mRNA; Isoproterenol results in increased expression of FOSL2 protein
[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of FOSL2 mRNA]; U 0126 inhibits the reaction [Isoproterenol results in increased expression of FOSL2 mRNA]
CTD PMID:21177286 NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
JBrowse link
G Foxo1 forkhead box O1 increases phosphorylation ISO Isoproterenol results in increased phosphorylation of FOXO1 protein CTD PMID:15618457 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Foxo3 forkhead box O3 increases expression ISO Isoproterenol results in increased expression of FOXO3 mRNA CTD PMID:20003209 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Fry FRY microtubule binding protein increases expression ISO Isoproterenol results in increased expression of FRY mRNA CTD PMID:20003209 NCBI chr12:4,493,890...4,887,118
Ensembl chr12:4,493,891...4,799,116
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions
increases expression
EXP CPU0213 inhibits the reaction [Isoproterenol results in increased expression of FSHB protein] CTD PMID:20307649 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO Isoproterenol results in increased expression of FTL1 mRNA CTD PMID:20003209 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
JBrowse link
G Fus Fus RNA binding protein decreases expression ISO Isoproterenol results in decreased expression of FUS mRNA CTD PMID:20003209 NCBI chr 1:182,576,479...182,590,417
Ensembl chr 1:182,576,545...182,590,414
JBrowse link
G G3bp2 G3BP stress granule assembly factor 2 multiple interactions
increases expression
EXP G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of MYH7 protein]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPA mRNA]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPA protein]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPB mRNA]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPB protein]; Isoproterenol promotes the reaction [G3BP2 protein binds to NFKBIA protein]
Isoproterenol results in increased expression of G3BP2 mRNA; Isoproterenol results in increased expression of G3BP2 protein
CTD PMID:28816235 NCBI chr14:15,932,403...16,020,555
Ensembl chr14:15,987,417...16,020,548
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
increases activity
EXP Atenolol inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]; Cycloheximide inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]; Dactinomycin inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]; Gallopamil inhibits the reaction [Isoproterenol results in increased activity of G6PD protein] CTD PMID:1978808 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 increases expression ISO Isoproterenol results in increased expression of GABARAPL1 mRNA CTD PMID:20003209 NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression ISO Isoproterenol results in increased expression of GADD45G mRNA CTD PMID:21823215 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions
decreases activity
increases expression
increases activity
EXP [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of GAL protein]; [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in decreased activity of GAL protein]; [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in increased activity of GAL protein]; Betaine inhibits the reaction [Isoproterenol results in decreased activity of GAL protein]; Betaine inhibits the reaction [Isoproterenol results in increased activity of GAL protein]; naringin inhibits the reaction [Isoproterenol results in increased activity of GAL protein]; S-allylcysteine inhibits the reaction [Isoproterenol results in increased expression of GAL mRNA] CTD PMID:2015110 PMID:11829124 PMID:14499179 PMID:17045618 PMID:17182065 More... NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
JBrowse link
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 increases expression ISO Isoproterenol results in increased expression of GALNT15 mRNA CTD PMID:20003209 NCBI chr16:7,227,232...7,267,002
Ensembl chr16:7,227,271...7,267,014
JBrowse link
G Gas5 growth arrest specific 5 increases expression
decreases expression
ISO
EXP
Isoproterenol results in increased expression of GAS5 mRNA
Isoproterenol results in decreased expression of GAS5 mRNA
CTD PMID:20003209 PMID:28526319 NCBI chr13:73,303,611...73,306,932 JBrowse link
G Gas6 growth arrest specific 6 multiple interactions
decreases expression
EXP natakalim inhibits the reaction [Isoproterenol results in decreased expression of GAS6 protein] CTD PMID:27890915 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Gata4 GATA binding protein 4 multiple interactions ISO
EXP
[Phenylephrine co-treated with Isoproterenol] results in increased expression of GATA4 mRNA
Isoproterenol promotes the reaction [NFATC1 protein binds to GATA4 protein]
CTD PMID:10710348 PMID:11435416 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
JBrowse link
G Gbp6 guanylate binding protein family member 6 increases expression ISO Isoproterenol results in increased expression of GBP6 mRNA CTD PMID:20003209 NCBI chr14:4,730,286...4,756,508
Ensembl chr14:4,730,453...4,839,062
Ensembl chr14:4,730,453...4,839,062
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO Isoproterenol results in decreased expression of GCLC mRNA CTD PMID:21335049 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression
decreases expression
multiple interactions
ISO
EXP
Isoproterenol results in increased expression of GCLM mRNA
Isoproterenol results in decreased expression of GCLM mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of GCLM mRNA
CTD PMID:20003209 PMID:21335049 PMID:30303030 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 increases expression ISO Isoproterenol results in increased expression of GCNT2 mRNA CTD PMID:20003209 NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611
JBrowse link
G Gda guanine deaminase increases expression ISO Isoproterenol results in increased expression of GDA mRNA CTD PMID:20003209 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of GEM mRNA] CTD PMID:18089841 NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
JBrowse link
G Gfpt2 glutamine-fructose-6-phosphate transaminase 2 increases expression ISO Isoproterenol results in increased expression of GFPT2 mRNA CTD PMID:20003209 NCBI chr10:34,115,005...34,161,329
Ensembl chr10:34,115,052...34,161,329
JBrowse link
G Ggt5 gamma-glutamyltransferase 5 increases expression ISO Isoproterenol results in increased expression of GGT5 mRNA CTD PMID:20003209 NCBI chr20:13,043,255...13,071,523
Ensembl chr20:13,043,257...13,071,450
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide increases expression EXP Isoproterenol results in increased expression of GHRL protein CTD PMID:20572026 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
JBrowse link
G Ghsr growth hormone secretagogue receptor increases expression EXP Isoproterenol results in increased expression of GHSR mRNA; Isoproterenol results in increased expression of GHSR protein CTD PMID:20572026 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865
JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 increases expression ISO Isoproterenol results in increased expression of GIGYF2 mRNA CTD PMID:20003209 NCBI chr 9:88,001,212...88,127,040
Ensembl chr 9:88,001,301...88,125,715
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
increases expression
decreases expression
EXP
ISO
[Isoproterenol co-treated with Metoprolol] results in increased expression of GJA1 protein
Doxycycline inhibits the reaction [Isoproterenol results in decreased expression of GJA1 mRNA]
Isoproterenol results in increased expression of GJA1 mRNA; Isoproterenol results in increased expression of GJA1 protein
CTD PMID:16352648 PMID:18089841 PMID:20003209 PMID:20215810 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gk glycerol kinase increases activity EXP Isoproterenol results in increased activity of GK protein CTD PMID:12736183 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631
JBrowse link
G Glb1 galactosidase, beta 1 multiple interactions
affects activity
increases activity
EXP caffeic acid inhibits the reaction [Isoproterenol affects the activity of GLB1 protein]; Phytic Acid inhibits the reaction [Isoproterenol results in increased activity of GLB1 protein] CTD PMID:20391626 PMID:25560919 NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127
JBrowse link
G Glg1 golgi glycoprotein 1 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of GLG1 mRNA CTD PMID:30303030 NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178
JBrowse link
G Glul glutamate-ammonia ligase increases expression ISO Isoproterenol results in increased expression of GLUL mRNA CTD PMID:20003209 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
JBrowse link
G Gna15 G protein subunit alpha 15 multiple interactions
increases response to substance
ISO [GNA15 protein results in increased susceptibility to Isoproterenol] which results in increased activity of ADRB2 protein CTD PMID:9875846 NCBI chr 7:8,184,632...8,205,508
Ensembl chr 7:8,184,861...8,205,508
JBrowse link
G Gnal G protein subunit alpha L increases response to substance
multiple interactions
ISO GNAL protein results in increased susceptibility to Isoproterenol
Egtazic Acid inhibits the reaction [GNAL protein results in increased susceptibility to Isoproterenol]
CTD PMID:15598656 NCBI chr18:60,622,311...60,762,599
Ensembl chr18:60,622,311...60,762,599
JBrowse link
G Gnas GNAS complex locus multiple interactions
increases response to substance
EXP
ISO
GNAS protein affects the susceptibility to [Potassium Chloride co-treated with Isoproterenol]; Isoproterenol affects the expression of and affects the localization of GNAS protein
GNAS protein results in increased susceptibility to Isoproterenol
Egtazic Acid inhibits the reaction [GNAS protein results in increased susceptibility to Isoproterenol]
CTD PMID:10696522 PMID:12376418 PMID:15598656 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262
JBrowse link
G Gng2 G protein subunit gamma 2 increases expression ISO Isoproterenol results in increased expression of GNG2 mRNA CTD PMID:20003209 NCBI chr15:4,316,038...4,416,918
Ensembl chr15:4,316,059...4,417,183
JBrowse link
G Gng3 G protein subunit gamma 3 multiple interactions EXP [Isoproterenol co-treated with Atorvastatin] affects the localization of GNG3 protein CTD PMID:19136528 NCBI chr 1:205,731,837...205,733,603
Ensembl chr 1:205,731,837...205,733,603
JBrowse link
G Gns glucosamine (N-acetyl)-6-sulfatase increases expression ISO Isoproterenol results in increased expression of GNS mRNA CTD PMID:20003209 NCBI chr 7:56,889,148...56,923,173
Ensembl chr 7:56,889,232...56,923,151
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions EXP Carvedilol inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of GOT1 protein]; imetit inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of GOT1 protein]; Isoproterenol results in increased expression of and results in increased secretion of GOT1 protein CTD PMID:25496245 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 decreases expression EXP Isoproterenol results in decreased expression of GOT2 protein CTD PMID:19826179 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression ISO Isoproterenol results in decreased expression of GPAM mRNA CTD PMID:21335049 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Gpcpd1 glycerophosphocholine phosphodiesterase 1 decreases expression ISO Isoproterenol results in decreased expression of GPCPD1 mRNA CTD PMID:20003209 NCBI chr 3:119,787,681...119,832,550
Ensembl chr 3:119,787,682...119,832,517
JBrowse link
G Gpihbp1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 increases expression ISO Isoproterenol results in increased expression of GPIHBP1 mRNA CTD PMID:20003209 NCBI chr 7:107,285,584...107,288,702
Ensembl chr 7:107,285,654...107,288,702
JBrowse link
G Gpnmb glycoprotein nmb increases expression ISO Isoproterenol results in increased expression of GPNMB mRNA CTD PMID:20003209 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
JBrowse link
G Gpr160 G protein-coupled receptor 160 increases expression ISO Isoproterenol results in increased expression of GPR160 mRNA CTD PMID:20003209 NCBI chr 2:112,483,364...112,563,072
Ensembl chr 2:112,484,935...112,563,148
JBrowse link
G Gpr182 G protein-coupled receptor 182 increases expression ISO Isoproterenol results in increased expression of GPR182 mRNA CTD PMID:20003209 NCBI chr 7:63,585,997...63,589,088
Ensembl chr 7:63,578,750...63,589,210
JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity
multiple interactions
EXP Isoproterenol results in increased activity of GPT protein
Carvedilol inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of GPT protein]; imetit inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of GPT protein]; Isoproterenol results in increased expression of and results in increased secretion of GPT protein; oleuropein inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of GPT protein]
CTD PMID:25496245 PMID:26056852 PMID:35130744 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
decreases activity
EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of GPX1 mRNA; benidipine inhibits the reaction [Isoproterenol results in decreased activity of GPX1 protein] CTD PMID:25269373 PMID:30303030 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO Isoproterenol results in increased expression of GPX3 mRNA CTD PMID:20003209 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 increases expression ISO Isoproterenol results in increased expression of GRINA mRNA CTD PMID:20003209 NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 increases expression
multiple interactions
EXP
ISO
Isoproterenol results in increased expression of GRK2 mRNA
AGT affects the reaction [Isoproterenol results in decreased expression of GRK2 mRNA]
Isoproterenol results in increased expression of GRK2 protein
Isoproterenol results in increased expression of GRK2 mRNA; Isoproterenol results in increased expression of GRK2 protein
CTD PMID:9788834 PMID:16731636 NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582
JBrowse link
G Grk5 G protein-coupled receptor kinase 5 increases expression ISO Isoproterenol results in increased expression of GRK5 mRNA CTD PMID:20003209 NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
decreases phosphorylation
increases phosphorylation
EXP
ISO
2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in decreased phosphorylation of GSK3B protein]; 2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein]; 2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one promotes the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein]; Enalapril inhibits the reaction [Isoproterenol results in decreased phosphorylation of GSK3B protein]; plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein]; Valsartan inhibits the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein] CTD PMID:15951400 PMID:16716347 PMID:18806606 PMID:31009642 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases expression
increases activity
decreases activity
EXP abana inhibits the reaction [Isoproterenol results in decreased expression of GSR]; allyl sulfide inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; benidipine inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; Catechin inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; Desmodium gangeticum extract inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; dicarbine inhibits the reaction [Isoproterenol results in increased activity of GSR protein]; Gallic Acid inhibits the reaction [Isoproterenol results in decreased expression of GSR protein]; mangiferin inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; S-allylcysteine inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; Tretinoin inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]
Isoproterenol results in decreased expression of GSR; Isoproterenol results in decreased expression of GSR protein
CTD PMID:1840475 PMID:12557918 PMID:15261977 PMID:15740881 PMID:16697266 More... NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases activity
multiple interactions
EXP Isoproterenol results in decreased activity of GSTA1 protein
benidipine inhibits the reaction [Isoproterenol results in decreased activity of GSTA1 protein]
CTD PMID:25269373 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsto1 glutathione S-transferase omega 1 decreases expression ISO Isoproterenol results in decreased expression of GSTO1 mRNA CTD PMID:21335049 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G Gtf2a1 general transcription factor 2A subunit 1 increases expression ISO Isoproterenol results in increased expression of GTF2A1 mRNA CTD PMID:20003209 NCBI chr 6:110,488,891...110,521,502
Ensembl chr 6:110,488,931...110,521,511
JBrowse link
G Gusb glucuronidase, beta multiple interactions
increases expression
decreases activity
increases activity
EXP [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; Betaine inhibits the reaction [Isoproterenol results in decreased activity of GUSB protein]; Betaine inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; caffeic acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; Curcumin inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; epigallocatechin gallate inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; mangiferin inhibits the reaction [Isoproterenol results in decreased activity of GUSB protein]; naringin inhibits the reaction [Isoproterenol results in decreased activity of GUSB protein]; naringin inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; Phytic Acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; S-allylcysteine inhibits the reaction [Isoproterenol results in increased expression of GUSB mRNA] CTD PMID:2015110 PMID:8534267 PMID:11829124 PMID:14499179 PMID:17045618 More... NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905
JBrowse link
G H19 H19 imprinted maternally expressed transcript increases expression
increases expression
ISO
EXP
Isoproterenol results in increased expression of H19 mRNA
isoprenaline increases expression of H19 RNA in cardiac muscle cells
CTD
RGD
PMID:20003209 PMID:27318893 RGD:156430318 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134
JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO Isoproterenol results in increased expression of H1F2 mRNA CTD PMID:20003209 NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635
JBrowse link
G H1f4 H1.4 linker histone, cluster member increases expression ISO Isoproterenol results in increased expression of H1F4 mRNA CTD PMID:20003209 NCBI chr17:41,486,574...41,487,355
Ensembl chr17:41,486,560...41,487,403
JBrowse link
G H2ax H2A.X variant histone increases expression ISO Isoproterenol results in increased expression of H2AX mRNA CTD PMID:21335049 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of HADHA mRNA CTD PMID:30303030 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
JBrowse link
G Haghl hydroxyacylglutathione hydrolase-like decreases expression ISO Isoproterenol results in decreased expression of HAGHL mRNA CTD PMID:20003209 NCBI chr10:14,804,957...14,809,495
Ensembl chr10:14,804,997...14,807,665
JBrowse link
G Hamp hepcidin antimicrobial peptide increases expression EXP
ISO
Isoproterenol results in increased expression of HAMP mRNA CTD PMID:20211217 PMID:21335049 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hap1 huntingtin-associated protein 1 increases expression ISO Isoproterenol results in increased expression of HAP1 mRNA CTD PMID:21335049 NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126
JBrowse link
G Harbi1 harbinger transposase derived 1 increases expression ISO Isoproterenol results in increased expression of HARBI1 mRNA CTD PMID:20003209 NCBI chr 3:77,681,431...77,689,749
Ensembl chr 3:77,681,431...77,689,724
JBrowse link
G Hdac2 histone deacetylase 2 increases phosphorylation
multiple interactions
ISO
EXP
Isoproterenol results in increased phosphorylation of HDAC2 protein
plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of HDAC2 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased phosphorylation of HDAC2 protein]
CTD PMID:31009642 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Heatr5b HEAT repeat containing 5B increases expression ISO Isoproterenol results in increased expression of HEATR5B mRNA CTD PMID:20003209 NCBI chr 6:16,243,424...16,323,444
Ensembl chr 6:16,243,461...16,323,435
JBrowse link
G Heca hdc homolog, cell cycle regulator increases expression ISO Isoproterenol results in increased expression of HECA mRNA CTD PMID:20003209 NCBI chr 1:12,525,445...12,575,358
Ensembl chr 1:12,525,135...12,576,427
JBrowse link
G Heph hephaestin increases expression ISO Isoproterenol results in increased expression of HEPH mRNA CTD PMID:20003209 NCBI chr  X:61,151,131...61,402,980
Ensembl chr  X:61,296,345...61,402,980
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Isoproterenol results in increased expression of HERPUD1 mRNA CTD PMID:20003209 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Herpud2 HERPUD family member 2 increases expression ISO Isoproterenol results in increased expression of HERPUD2 mRNA CTD PMID:20003209 NCBI chr 8:23,573,374...23,618,380
Ensembl chr 8:23,573,379...23,617,874
JBrowse link
G Hes1 hes family bHLH transcription factor 1 decreases expression ISO Isoproterenol results in decreased expression of HES1 mRNA CTD PMID:20003209 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hexa hexosaminidase subunit alpha increases expression ISO Isoproterenol results in increased expression of HEXA mRNA CTD PMID:20003209 NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013
JBrowse link
G Hfe homeostatic iron regulator increases expression ISO Isoproterenol results in increased expression of HFE mRNA CTD PMID:20003209 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression ISO Isoproterenol results in decreased expression of HIF1A mRNA CTD PMID:20003209 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor decreases expression ISO Isoproterenol results in decreased expression of HIF1AN mRNA CTD PMID:24286936 NCBI chr 1:243,419,175...243,440,464
Ensembl chr 1:243,419,194...243,434,327
JBrowse link
G Hif3a hypoxia inducible factor 3 subunit alpha increases expression ISO
EXP
Isoproterenol results in increased expression of HIF3A mRNA CTD PMID:24286936 NCBI chr 1:77,718,110...77,750,448
Ensembl chr 1:77,722,471...77,749,758
JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 increases expression ISO Isoproterenol results in increased expression of HIPK1 mRNA CTD PMID:20003209 NCBI chr 2:191,248,817...191,299,787
Ensembl chr 2:191,248,817...191,298,902
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 decreases expression ISO Isoproterenol results in decreased expression of HIPK2 mRNA CTD PMID:20003209 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
JBrowse link
G Hipk3 homeodomain interacting protein kinase 3 increases expression ISO Isoproterenol results in increased expression of HIPK3 mRNA CTD PMID:20003209 NCBI chr 3:90,796,980...90,866,701
Ensembl chr 3:90,800,296...90,867,759
JBrowse link
G Hk2 hexokinase 2 decreases expression ISO Isoproterenol results in decreased expression of HK2 mRNA CTD PMID:20003209 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Hlf HLF transcription factor, PAR bZIP family member decreases expression ISO Isoproterenol results in decreased expression of HLF mRNA CTD PMID:20003209 NCBI chr10:75,154,244...75,211,884
Ensembl chr10:75,154,507...75,211,935
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases activity
EXP 7-hydroxycoumarin inhibits the reaction [Isoproterenol results in increased activity of HMGCR protein]; [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased activity of HMGCR protein]; alliin inhibits the reaction [Isoproterenol results in increased activity of HMGCR protein]; naringin inhibits the reaction [Isoproterenol results in increased activity of HMGCR protein] CTD PMID:16640830 PMID:16906524 PMID:19595682 PMID:26995004 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Isoproterenol results in increased expression of HMGCS1 mRNA CTD PMID:21335049 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
decreases expression
ISO
EXP
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of HMOX1 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of HMOX1 protein]
Isoproterenol results in increased expression of HMOX1 mRNA
[erdosteine co-treated with Isoproterenol] results in increased expression of HMOX1 protein; anethole promotes the reaction [Isoproterenol results in increased expression of HMOX1 mRNA]; anethole promotes the reaction [Isoproterenol results in increased expression of HMOX1 protein]; Doxorubicin inhibits the reaction [Isoproterenol results in increased expression of HMOX1 mRNA]; protocatechuic acid inhibits the reaction [Isoproterenol results in decreased expression of HMOX1 mRNA]; punicalagin inhibits the reaction [Isoproterenol results in decreased expression of HMOX1 protein]
Isoproterenol results in increased expression of HMOX1 mRNA; Isoproterenol results in increased expression of HMOX1 protein
Isoproterenol results in decreased expression of HMOX1 mRNA; Isoproterenol results in decreased expression of HMOX1 protein
CTD PMID:15179140 PMID:19483313 PMID:20003209 PMID:21823215 PMID:22908232 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnrnph3 heterogeneous nuclear ribonucleoprotein H3 decreases expression ISO Isoproterenol results in decreased expression of HNRNPH3 mRNA CTD PMID:20003209 NCBI chr20:25,616,400...25,625,814
Ensembl chr20:25,614,733...25,625,750
JBrowse link
G Hnrnpr heterogeneous nuclear ribonucleoprotein R decreases expression ISO Isoproterenol results in decreased expression of HNRNPR mRNA CTD PMID:20003209 NCBI chr 5:148,542,999...148,574,888
Ensembl chr 5:148,543,044...148,574,867
JBrowse link
G Homer1 homer scaffold protein 1 increases expression EXP Isoproterenol results in increased expression of HOMER1 mRNA alternative form CTD PMID:16786172 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785
JBrowse link
G Hopx HOP homeobox decreases expression ISO Isoproterenol results in decreased expression of HOPX mRNA CTD PMID:20003209 NCBI chr14:31,055,912...31,082,909
Ensembl chr14:31,075,148...31,082,909
JBrowse link
G Hpca hippocalcin affects localization EXP Isoproterenol affects the localization of HPCA protein CTD PMID:21078978 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841
JBrowse link
G Hpse heparanase increases expression EXP Isoproterenol results in increased expression of HPSE protein CTD PMID:16327176 NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010
JBrowse link
G Hras HRas proto-oncogene, GTPase increases activity EXP Isoproterenol results in increased activity of HRAS protein CTD PMID:8484791 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 decreases expression ISO Isoproterenol results in decreased expression of HS2ST1 mRNA CTD PMID:20003209 NCBI chr 2:233,508,018...233,641,769
Ensembl chr 2:233,508,021...233,641,769
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO Isoproterenol results in decreased expression of HSD3B1 mRNA; Isoproterenol results in decreased expression of HSD3B2 mRNA CTD PMID:21335049 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO Isoproterenol results in increased expression of HSP90AA1 mRNA CTD PMID:21335049 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 decreases expression ISO Isoproterenol results in decreased expression of HSP90B1 mRNA CTD PMID:20003209 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like increases expression
decreases expression
ISO
EXP
Isoproterenol results in increased expression of HSPA1L mRNA
Isoproterenol results in decreased expression of HSPA1L mRNA
CTD PMID:20003209 PMID:24286936 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression EXP
ISO
Isoproterenol results in increased expression of HSPA2 mRNA CTD PMID:20211217 PMID:24286936 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
decreases expression
multiple interactions
ISO
EXP
Isoproterenol results in increased expression of HSPA5 mRNA
Isoproterenol results in decreased expression of HSPA5 mRNA
[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of HSPA5 protein; Acrolein promotes the reaction [Isoproterenol results in increased expression of HSPA5 mRNA]; Plant Extracts inhibits the reaction [[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of HSPA5 protein]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of HSPA5 mRNA]]
CTD PMID:21335049 PMID:24286936 PMID:29414845 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO Isoproterenol results in decreased expression of HSPA8 mRNA CTD PMID:20003209 PMID:24286936 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions
increases expression
EXP Curcumin promotes the reaction [Isoproterenol results in increased expression of HSPB1 protein]
Isoproterenol results in increased expression of HSP27 protein; Isoproterenol results in increased expression of HSPB1 protein
CTD PMID:10559386 PMID:20125031 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hspb7 heat shock protein family B (small) member 7 increases expression EXP Isoproterenol results in increased expression of HSPB7 mRNA CTD PMID:24286936 NCBI chr 5:153,727,782...153,731,268
Ensembl chr 5:153,727,588...153,731,266
JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 decreases expression ISO Isoproterenol results in decreased expression of HSPG2 mRNA CTD PMID:20003209 NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO Isoproterenol results in increased expression of HSPH1 mRNA CTD PMID:21335049 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Htra2 HtrA serine peptidase 2 decreases expression ISO Isoproterenol results in decreased expression of HTRA2 mRNA CTD PMID:21335049 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Htra3 HtrA serine peptidase 3 increases expression ISO Isoproterenol results in increased expression of HTRA3 mRNA CTD PMID:20003209 NCBI chr14:75,068,917...75,097,315
Ensembl chr14:75,068,917...75,097,315
JBrowse link
G Hyou1 hypoxia up-regulated 1 decreases expression ISO Isoproterenol results in decreased expression of HYOU1 mRNA CTD PMID:20003209 NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Isoproterenol results in increased expression of ICAM1 mRNA CTD PMID:20003209 PMID:21335049 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id1 inhibitor of DNA binding 1 decreases expression
increases expression
ISO
EXP
Isoproterenol results in decreased expression of ID1 mRNA
isoprenaline increases expression of mRNA in neonatal rat cardiomyocytes
CTD
RGD
PMID:21335049 PMID:26873969 RGD:11526363 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Ier3 immediate early response 3 multiple interactions
affects response to substance
ISO IER3 protein affects the reaction [Isoproterenol results in increased abundance of Cyclic AMP]; Pertussis Toxin affects the reaction [IER3 protein affects the reaction [Isoproterenol results in increased abundance of Cyclic AMP]]; Pertussis Toxin affects the reaction [IER3 protein affects the susceptibility to Isoproterenol] CTD PMID:20713914 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Ifna1 interferon, alpha 1 decreases expression EXP Isoproterenol results in decreased expression of IFNA1 mRNA CTD PMID:24286936 NCBI chr 5:103,097,356...103,097,925
Ensembl chr 5:103,097,356...103,097,925
JBrowse link
G Ifng interferon gamma decreases secretion ISO Isoproterenol results in decreased secretion of IFNG protein CTD PMID:15342205 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ifngr2 interferon gamma receptor 2 decreases expression ISO Isoproterenol results in decreased expression of IFNGR2 mRNA CTD PMID:20003209 NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression ISO Isoproterenol results in increased expression of IFRD1 mRNA CTD PMID:20003209 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
JBrowse link
G Ift74 intraflagellar transport 74 increases expression ISO Isoproterenol results in increased expression of IFT74 mRNA CTD PMID:20003209 NCBI chr 5:109,460,372...109,563,839
Ensembl chr 5:109,474,255...109,563,833
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression
multiple interactions
increases expression
ISO
EXP
Isoproterenol results in decreased expression of IGF1 mRNA
candesartan cilexetil inhibits the reaction [Isoproterenol results in increased expression of IGF1 mRNA]; candesartan cilexetil inhibits the reaction [Isoproterenol results in increased expression of IGF1 protein]
Isoproterenol results in increased expression of IGF1 mRNA; Isoproterenol results in increased expression of IGF1 protein
CTD PMID:10547078 PMID:20003209 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression ISO Isoproterenol results in increased expression of IGF1R mRNA CTD PMID:20003209 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Igf2bp2 insulin-like growth factor 2 mRNA binding protein 2 increases expression ISO Isoproterenol results in increased expression of IGF2BP2 mRNA CTD PMID:20003209 NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression
multiple interactions
EXP Isoproterenol results in decreased expression of IGFBP3
SI 27 inhibits the reaction [Isoproterenol results in decreased expression of IGFBP3]
CTD PMID:12883319 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
JBrowse link
G Il10 interleukin 10 multiple interactions
decreases expression
ISO
EXP
Isoproterenol promotes the reaction [Lipopolysaccharides results in increased expression of IL10 protein]
Isoproterenol results in decreased expression of IL10 protein
Quercetin inhibits the reaction [Isoproterenol results in decreased expression of IL10 protein]
CTD PMID:9038718 PMID:27527349 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il12a interleukin 12A decreases expression EXP Isoproterenol results in decreased expression of IL12A protein CTD PMID:24286936 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B increases expression ISO Isoproterenol results in increased expression of IL12B protein CTD PMID:24286936 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il17a interleukin 17A increases expression
multiple interactions
EXP Isoproterenol results in increased expression of IL17A protein
Glyburide promotes the reaction [Isoproterenol results in increased expression of IL17A protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of IL17A protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of IL17A protein]
CTD PMID:19909738 PMID:35305975 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il17rd interleukin 17 receptor D increases expression ISO Isoproterenol results in increased expression of IL17RD mRNA CTD PMID:20003209 NCBI chr16:2,228,438...2,295,122
Ensembl chr16:2,228,287...2,292,556
JBrowse link
G Il18 interleukin 18 multiple interactions
decreases expression
increases expression
ISO
EXP
ADRB2 protein affects the reaction [Isoproterenol results in increased expression of IL18 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Isoproterenol results in increased secretion of IL18 protein]; ICI 118551 inhibits the reaction [Isoproterenol results in increased expression of IL18 mRNA]; ICI 118551 inhibits the reaction [Isoproterenol results in increased expression of IL18 protein]; Isoproterenol results in increased expression of and results in increased secretion of IL18 protein; Isoproterenol results in increased expression of and results in increased stability of IL18 mRNA; Pertussis Toxin inhibits the reaction [Isoproterenol results in increased secretion of IL18 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of IL18 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of IL18 mRNA]; wortmannin inhibits the reaction [Isoproterenol results in increased secretion of IL18 protein]
Isoproterenol results in decreased expression of IL18 mRNA
CTD PMID:15178407 PMID:21335049 PMID:24286936 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha decreases expression
increases expression
ISO
EXP
Isoproterenol results in decreased expression of IL1A mRNA
Isoproterenol results in increased expression of IL1A mRNA
CTD PMID:24286936 PMID:32816093 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
decreases expression
ISO
EXP
SB 206553 inhibits the reaction [Isoproterenol results in increased expression of IL1B]; ZD 7155 inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]
5-Methoxypsoralen inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; anethole inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]; Glyburide promotes the reaction [Isoproterenol results in increased expression of IL1B protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; punicalagin inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of IL1B protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]]
Isoproterenol results in increased expression of IL1B; Isoproterenol results in increased expression of IL1B mRNA; Isoproterenol results in increased expression of IL1B protein
Isoproterenol results in decreased expression of IL1B mRNA; Isoproterenol results in decreased expression of IL1B protein
CTD PMID:9387890 PMID:12215284 PMID:15302781 PMID:18487443 PMID:19023134 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist affects response to substance ISO IL1RN protein affects the susceptibility to Isoproterenol CTD PMID:10487780 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il2 interleukin 2 increases expression
multiple interactions
EXP Isoproterenol results in increased expression of IL2 mRNA; Isoproterenol results in increased expression of IL2 protein
Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL2 mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL2 protein]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL2 mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL2 protein]]
CTD PMID:25045214 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il24 interleukin 24 increases expression ISO Isoproterenol results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
JBrowse link
G Il4 interleukin 4 decreases expression
increases expression
ISO
EXP
Isoproterenol results in decreased expression of IL4 mRNA
Isoproterenol results in increased expression of IL4 protein
Isoproterenol results in increased expression of IL4 mRNA
CTD PMID:24286936 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il4r interleukin 4 receptor increases expression ISO Isoproterenol results in increased expression of IL4RA mRNA CTD PMID:20003209 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Il5ra interleukin 5 receptor subunit alpha affects response to substance ISO IL5RA protein affects the susceptibility to Isoproterenol CTD PMID:10487780 NCBI chr 4:139,630,652...139,664,593
Ensembl chr 4:139,632,066...139,668,544
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases secretion
increases expression
increases secretion
decreases expression
ISO
EXP
ANXA1 affects the reaction [Isoproterenol results in decreased secretion of IL6 protein]; biochanin A inhibits the reaction [Isoproterenol results in increased expression of IL6 mRNA]; Genistein promotes the reaction [Isoproterenol results in increased secretion of IL6 protein]; Isoproterenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; oxophenylarsine inhibits the reaction [Isoproterenol results in increased secretion of IL6 protein]; SB 206553 inhibits the reaction [Isoproterenol results in increased expression of IL6]; ZD 7155 inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]
Isoproterenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]
Isoproterenol results in increased expression of IL6; Isoproterenol results in increased expression of IL6 mRNA; Isoproterenol results in increased expression of IL6 protein
5-Methoxypsoralen inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; anethole inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; Apigenin inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL6 mRNA]; Enalapril inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; erdosteine inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; ferruginol inhibits the reaction [Isoproterenol results in increased secretion of IL6 protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; Hesperidin inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; ICI 118551 inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; ICI 118551 inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; Isoproterenol inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Isoproterenol results in increased expression of and results in increased secretion of IL6 protein; Metformin inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of IL6 protein]; Metformin inhibits the reaction [Isoproterenol results in increased expression of IL6 mRNA]; punicalagin inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; xanthone inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]
Isoproterenol results in decreased expression of IL6 mRNA
CTD PMID:9038718 PMID:9688336 PMID:10525314 PMID:11406463 PMID:15302781 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il7 interleukin 7 increases expression ISO
EXP
Isoproterenol results in increased expression of IL7 protein CTD PMID:24286936 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
JBrowse link
G Immt inner membrane mitochondrial protein decreases expression ISO Isoproterenol results in decreased expression of IMMT mRNA CTD PMID:20003209 NCBI chr 4:103,880,482...103,919,116
Ensembl chr 4:103,880,459...103,919,109
JBrowse link
G Inhbb inhibin subunit beta B increases expression ISO Isoproterenol results in increased expression of INHBB mRNA CTD PMID:20003209 NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832
JBrowse link
G Ins2 insulin 2 multiple interactions
affects expression
increases expression
EXP INS protein inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]; OPC 3911 inhibits the reaction [INS protein inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]]
Isoproterenol affects the expression of INS protein
Isoproterenol results in increased expression of INS protein
CTD PMID:1129332 PMID:1170870 PMID:19167487 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Ints3 integrator complex subunit 3 increases expression ISO Isoproterenol results in increased expression of INTS3 mRNA CTD PMID:20003209 NCBI chr 2:175,859,421...175,911,683
Ensembl chr 2:175,859,440...175,911,709
JBrowse link
G Ipo13 importin 13 decreases expression ISO Isoproterenol results in decreased expression of IPO13 mRNA CTD PMID:20003209 NCBI chr 5:131,433,770...131,454,044
Ensembl chr 5:131,433,776...131,454,043
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 increases expression ISO Isoproterenol results in increased expression of IRAK3 mRNA CTD PMID:20003209 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121
JBrowse link
G Irs1 insulin receptor substrate 1 increases expression ISO Isoproterenol results in increased expression of IRS1 mRNA CTD PMID:20003209 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Irx4 iroquois homeobox 4 decreases expression ISO Isoproterenol results in decreased expression of IRX4 mRNA CTD PMID:20003209 NCBI chr 1:30,030,561...30,039,549
Ensembl chr 1:30,030,561...30,039,549
JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO Isoproterenol promotes the reaction [Theophylline inhibits the reaction [Platelet Activating Factor results in increased expression of ITGAM protein]] CTD PMID:9762784 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions
decreases expression
ISO
EXP
DMD gene mutant form promotes the reaction [ITGB1 gene affects the susceptibility to Isoproterenol]
Isoproterenol results in decreased expression of ITGB1
CTD PMID:18340010 PMID:18808529 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgbl1 integrin subunit beta like 1 increases expression ISO Isoproterenol results in increased expression of ITGBL1 mRNA CTD PMID:20003209 NCBI chr15:100,780,184...101,041,734
Ensembl chr15:100,780,184...101,041,733
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 increases expression ISO Isoproterenol results in increased expression of ITIH3 mRNA CTD PMID:20003209 NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924
JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 increases expression ISO Isoproterenol results in increased expression of ITIH4 mRNA CTD PMID:20003209 NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708
JBrowse link
G Itk IL2-inducible T-cell kinase decreases expression ISO Isoproterenol results in decreased expression of ITK mRNA CTD PMID:20003209 NCBI chr10:30,753,344...30,814,685
Ensembl chr10:30,753,344...30,814,685
JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B decreases expression ISO Isoproterenol results in decreased expression of ITPKB mRNA CTD PMID:20003209 NCBI chr13:92,069,160...92,164,281
Ensembl chr13:92,069,216...92,162,004
JBrowse link
G Jade2 jade family PHD finger 2 increases expression ISO Isoproterenol results in increased expression of JADE2 mRNA CTD PMID:20003209 NCBI chr10:36,075,239...36,124,210
Ensembl chr10:36,078,917...36,116,984
JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 decreases expression ISO Isoproterenol results in decreased expression of JARID2 mRNA CTD PMID:20003209 NCBI chr17:19,777,487...19,957,696
Ensembl chr17:19,777,266...19,955,690
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
decreases expression
ISO
EXP
[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of JUN mRNA]; [Phenylephrine co-treated with Isoproterenol] results in increased expression of JUN mRNA; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of JUN mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of JUN mRNA]
[Isoproterenol co-treated with POSTN protein] results in decreased expression of JUN mRNA; Isoproterenol promotes the reaction [JUN protein binds to FOS protein]
Isoproterenol results in increased expression of JUN mRNA; Isoproterenol results in increased expression of JUN protein
Isoproterenol results in decreased expression of JUN mRNA
CTD PMID:10710348 PMID:14764439 PMID:21177286 PMID:30303030 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
EXP
ISO
Isoproterenol results in increased expression of JUNB
Isoproterenol results in increased expression of JUNB mRNA; Isoproterenol results in increased expression of JUNB protein
[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of JUNB mRNA]; JUNB protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; JUNB protein promotes the reaction [Isoproterenol results in decreased expression of SOX6 mRNA]; JUNB protein promotes the reaction [Isoproterenol results in decreased expression of SOX6 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of JUNB mRNA]; U 0126 inhibits the reaction [Isoproterenol results in increased expression of JUNB mRNA]
CTD PMID:7905536 PMID:21177286 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Kank3 KN motif and ankyrin repeat domains 3 increases expression ISO Isoproterenol results in increased expression of KANK3 mRNA CTD PMID:20003209 NCBI chr 7:14,594,358...14,607,675
Ensembl chr 7:14,594,422...14,607,675
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 increases expression ISO Isoproterenol results in increased expression of KCNA5 mRNA CTD PMID:20003209 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697
JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 decreases expression ISO Isoproterenol results in decreased expression of KCNB1 mRNA CTD PMID:20003209 NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194
JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 decreases expression ISO Isoproterenol results in decreased expression of KCND2 mRNA CTD PMID:20003209 NCBI chr 4:49,775,812...50,277,746
Ensembl chr 4:49,776,246...50,277,728
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 multiple interactions
decreases expression
ISO Isoproterenol results in increased activity of [KCNQ1 protein binds to KCNE1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased activity of [KCNQ1 protein binds to KCNE1 protein]]
Isoproterenol results in decreased expression of KCNE1 mRNA
CTD PMID:16909339 PMID:20003209 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
JBrowse link
G Kcnh6 potassium voltage-gated channel subfamily H member 6 increases expression ISO Isoproterenol results in increased expression of KCNH6 mRNA CTD PMID:20003209 NCBI chr10:90,949,240...90,970,746
Ensembl chr10:90,949,846...90,970,701
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 multiple interactions ISO
EXP
Isoproterenol results in increased activity of [KCNQ1 protein binds to KCNE1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased activity of [KCNQ1 protein binds to KCNE1 protein]]
[Isoproterenol co-treated with POSTN protein] results in decreased expression of KCNQ1 mRNA
CTD PMID:16909339 PMID:30303030 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Kcnt2 potassium sodium-activated channel subfamily T member 2 increases expression ISO Isoproterenol results in increased expression of KCNT2 mRNA CTD PMID:20003209 NCBI chr13:51,664,129...52,059,209
Ensembl chr13:51,664,686...52,056,987
JBrowse link
G Kdm6b lysine demethylase 6B decreases expression ISO Isoproterenol results in decreased expression of KDM6B mRNA CTD PMID:20003209 NCBI chr10:54,120,716...54,142,212
Ensembl chr10:54,121,848...54,130,794
JBrowse link
G Kdr kinase insert domain receptor decreases expression ISO Isoproterenol results in decreased expression of KDR mRNA CTD PMID:20003209 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression
multiple interactions
increases expression
EXP Isoproterenol results in decreased expression of KEAP1 mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of KEAP1 mRNA; anethole inhibits the reaction [Isoproterenol results in increased expression of KEAP1 mRNA]; anethole inhibits the reaction [Isoproterenol results in increased expression of KEAP1 protein]
Isoproterenol results in increased expression of KEAP1 mRNA; Isoproterenol results in increased expression of KEAP1 protein
CTD PMID:30303030 PMID:35430261 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Kif1b kinesin family member 1B decreases expression ISO Isoproterenol results in decreased expression of KIF1B mRNA CTD PMID:20003209 NCBI chr 5:159,607,697...159,742,778
Ensembl chr 5:159,561,271...159,742,778
JBrowse link
G Klf15 KLF transcription factor 15 increases expression ISO Isoproterenol results in increased expression of KLF15 mRNA CTD PMID:20003209 NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374
JBrowse link
G Klf3 KLF transcription factor 3 increases expression ISO Isoproterenol results in increased expression of KLF3 mRNA CTD PMID:20003209 NCBI chr14:43,474,767...43,505,801
Ensembl chr14:43,474,767...43,497,209
JBrowse link
G Klhdc8a kelch domain containing 8A decreases expression ISO Isoproterenol results in decreased expression of KLHDC8A mRNA CTD PMID:20003209 NCBI chr13:43,735,702...43,744,277
Ensembl chr13:43,736,192...43,744,277
JBrowse link
G Klhl2 kelch-like family member 2 increases expression ISO Isoproterenol results in increased expression of KLHL2 mRNA CTD PMID:20003209 NCBI chr16:24,860,744...24,973,348
Ensembl chr16:24,860,667...24,973,341
JBrowse link
G Klhl24 kelch-like family member 24 increases expression ISO Isoproterenol results in increased expression of KLHL24 mRNA CTD PMID:20003209 NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636
JBrowse link
G Klhl40 kelch-like family member 40 increases expression EXP Isoproterenol results in increased expression of KLHL40 mRNA CTD PMID:20211217 NCBI chr 8:121,441,285...121,446,801
Ensembl chr 8:121,441,287...121,446,800
JBrowse link
G Klhl41 kelch-like family member 41 increases expression EXP Isoproterenol results in increased expression of KLHL41 mRNA CTD PMID:20211217 NCBI chr 3:54,434,291...54,447,415
Ensembl chr 3:54,434,234...54,449,222
JBrowse link
G Klhl7 kelch-like family member 7 increases expression ISO Isoproterenol results in increased expression of KLHL7 mRNA CTD PMID:20003209 NCBI chr 4:11,006,366...11,055,399
Ensembl chr 4:11,006,375...11,055,541
JBrowse link
G Kmt5a lysine methyltransferase 5A decreases expression ISO Isoproterenol results in decreased expression of KMT5A mRNA CTD PMID:20003209 NCBI chr12:32,139,353...32,167,777
Ensembl chr12:32,139,178...32,162,711
JBrowse link
G Kpna3 karyopherin subunit alpha 3 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of KPNA3 mRNA CTD PMID:30303030 NCBI chr15:35,536,310...35,610,066
Ensembl chr15:35,536,316...35,610,419
JBrowse link
G Kpna6 karyopherin subunit alpha 6 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of KPNA6 mRNA CTD PMID:30303030 NCBI chr 5:141,988,111...142,021,483
Ensembl chr 5:141,991,568...142,021,120
JBrowse link
G Kras KRAS proto-oncogene, GTPase increases expression ISO Isoproterenol results in increased expression of KRAS mRNA CTD PMID:21335049 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Krt18 keratin 18 increases expression ISO Isoproterenol results in increased expression of KRT18 mRNA CTD PMID:21335049 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
JBrowse link
G Krt222 keratin 222 decreases expression ISO Isoproterenol results in decreased expression of KRT222 mRNA CTD PMID:20003209 NCBI chr10:84,184,137...84,196,122
Ensembl chr10:84,186,173...84,196,015
JBrowse link
G Ky kyphoscoliosis peptidase decreases expression ISO Isoproterenol results in decreased expression of KY mRNA CTD PMID:20003209 NCBI chr 8:103,086,959...103,126,305
Ensembl chr 8:103,086,630...103,126,024
JBrowse link
G Lama2 laminin subunit alpha 2 decreases expression EXP Isoproterenol results in decreased expression of LAMA2 CTD PMID:18808529 NCBI chr 1:17,672,675...18,320,641
Ensembl chr 1:17,672,536...18,320,530
JBrowse link
G Lamb1 laminin subunit beta 1 decreases expression ISO Isoproterenol results in decreased expression of LAMB1 mRNA CTD PMID:20003209 NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
JBrowse link
G Lbh LBH regulator of WNT signaling pathway decreases expression ISO Isoproterenol results in decreased expression of LBH mRNA CTD PMID:20003209 NCBI chr 6:22,569,238...22,593,056
Ensembl chr 6:22,568,834...22,593,079
JBrowse link
G Lbp lipopolysaccharide binding protein increases expression ISO Isoproterenol results in increased expression of LBP mRNA CTD PMID:20003209 PMID:21335049 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
JBrowse link
G Lcat lecithin cholesterol acyltransferase multiple interactions
decreases activity
EXP [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein]; alliin inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein]; Desmodium gangeticum extract inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein]; epigallocatechin gallate inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein]; naringin inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein] CTD PMID:15740881 PMID:16640830 PMID:16906524 PMID:19595682 PMID:20024955 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lcn2 lipocalin 2 multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of LCN2 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions
increases secretion
increases expression
EXP [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased expression of LDHA protein]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of LDHA protein]; benidipine inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of LDHA protein]; caffeic acid inhibits the reaction [Isoproterenol results in increased expression of LDHA protein]; Gallic Acid inhibits the reaction [Isoproterenol results in increased secretion of LDHA protein]; Isoproterenol results in increased expression of and results in increased secretion of LDHA protein; naringin inhibits the reaction [Isoproterenol results in increased expression of LDHA protein]; oleuropein inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of LDHA protein] CTD PMID:17188415 PMID:19146839 PMID:21322096 PMID:21472895 PMID:21671307 More... NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Ldhb lactate dehydrogenase B multiple interactions
increases secretion
increases expression
EXP [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased expression of LDHB protein]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of LDHB protein]; caffeic acid inhibits the reaction [Isoproterenol results in increased expression of LDHB protein]; Gallic Acid inhibits the reaction [Isoproterenol results in increased secretion of LDHB protein]; naringin inhibits the reaction [Isoproterenol results in increased expression of LDHB protein] CTD PMID:17188415 PMID:19146839 PMID:21322096 PMID:21472895 PMID:21671307 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403
JBrowse link
G Lep leptin decreases secretion
multiple interactions
increases expression
increases secretion
ISO
EXP
Isoproterenol results in decreased secretion of LEP protein
Propranolol inhibits the reaction [Isoproterenol results in decreased secretion of LEP protein]
CPU0213 inhibits the reaction [Isoproterenol results in increased expression of LEP protein]
Isoproterenol results in increased secretion of LEP protein
CTD PMID:11022189 PMID:20307649 PMID:25111128 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lepr leptin receptor multiple interactions
increases expression
EXP CPU0213 inhibits the reaction [Isoproterenol results in increased expression of LEPR mRNA]; CPU0213 inhibits the reaction [Isoproterenol results in increased expression of LEPR protein]
Isoproterenol results in increased expression of LEPR mRNA; Isoproterenol results in increased expression of LEPR protein
CTD PMID:20307649 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Lgals3 galectin 3 increases expression ISO Isoproterenol results in increased expression of LGALS3 mRNA CTD PMID:20003209 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Lgi1 leucine-rich, glioma inactivated 1 decreases expression ISO Isoproterenol results in decreased expression of LGI1 mRNA CTD PMID:20003209 NCBI chr 1:236,043,269...236,084,617
Ensembl chr 1:236,042,954...236,084,616
JBrowse link
G Lgr6 leucine-rich repeat-containing G protein-coupled receptor 6 decreases expression ISO Isoproterenol results in decreased expression of LGR6 mRNA CTD PMID:20003209 NCBI chr13:46,424,382...46,544,074
Ensembl chr13:46,424,383...46,543,945
JBrowse link
G Limd1 LIM domain containing 1 increases expression ISO Isoproterenol results in increased expression of LIMD1 mRNA CTD PMID:20003209 NCBI chr 8:123,121,363...123,168,476
Ensembl chr 8:123,122,460...123,167,714
JBrowse link
G Lin7a lin-7 homolog A, crumbs cell polarity complex component increases expression ISO Isoproterenol results in increased expression of LIN7A mRNA CTD PMID:20003209 NCBI chr 7:42,586,704...42,742,609
Ensembl chr 7:42,586,719...42,730,550
JBrowse link
G Lipe lipase E, hormone sensitive type increases phosphorylation
multiple interactions
increases activity
affects localization
ISO
EXP
Isoproterenol results in increased phosphorylation of LIPE protein
Sirolimus promotes the reaction [Isoproterenol results in increased phosphorylation of LIPE protein]
Isoproterenol results in increased activity of LIPE protein
Papaverine inhibits the reaction [Isoproterenol affects the localization of LIPE protein]; Papaverine inhibits the reaction [Isoproterenol results in increased activity of LIPE protein]
CTD PMID:10894095 PMID:11160373 PMID:21042876 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor increases expression ISO Isoproterenol results in increased expression of LITAF mRNA CTD PMID:20003209 PMID:21335049 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763
JBrowse link
G Lman1 lectin, mannose-binding, 1 increases expression ISO Isoproterenol results in increased expression of LMAN1 mRNA CTD PMID:21823215 NCBI chr18:59,508,996...59,530,873
Ensembl chr18:59,508,996...59,530,851
JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 increases expression EXP Isoproterenol results in increased expression of LMCD1 mRNA CTD PMID:20211217 PMID:23558518 NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046
JBrowse link
G Lmod3 leiomodin 3 decreases expression ISO Isoproterenol results in decreased expression of LMOD3 mRNA CTD PMID:20003209 NCBI chr 4:129,843,964...129,858,684
Ensembl chr 4:129,843,970...129,858,244
JBrowse link
G Lonrf3 LON peptidase N-terminal domain and ring finger 3 increases expression ISO Isoproterenol results in increased expression of LONRF3 mRNA CTD PMID:20003209 NCBI chr  X:115,565,214...115,603,886
Ensembl chr  X:115,565,267...115,598,809
JBrowse link
G Lox lysyl oxidase increases expression ISO Isoproterenol results in increased expression of LOX mRNA CTD PMID:20003209 NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Lpl lipoprotein lipase multiple interactions
decreases activity
increases expression
decreases expression
EXP
ISO
cirazoline promotes the reaction [Isoproterenol results in increased expression of LPL mRNA]; naringin inhibits the reaction [Isoproterenol results in decreased activity of LPL protein]
Isoproterenol results in decreased expression of LPL mRNA
CTD PMID:9032464 PMID:16906524 PMID:21335049 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Lrat lecithin retinol acyltransferase decreases expression ISO Isoproterenol results in decreased expression of LRAT mRNA CTD PMID:20003209 NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 increases expression ISO Isoproterenol results in increased expression of LRG1 mRNA CTD PMID:20003209 NCBI chr 9:947,516...949,773
Ensembl chr 9:947,516...949,813
JBrowse link
G Lrpprc leucine-rich pentatricopeptide repeat containing multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of LRPPRC mRNA CTD PMID:30303030 NCBI chr 6:9,859,816...9,942,294
Ensembl chr 6:9,859,867...9,942,293
JBrowse link
G Lrrc52 leucine rich repeat containing 52 increases expression ISO Isoproterenol results in increased expression of LRRC52 mRNA CTD PMID:20003209 NCBI chr13:79,597,244...79,620,640
Ensembl chr13:79,597,245...79,620,640
JBrowse link
G Lrrc58 leucine rich repeat containing 58 increases expression ISO Isoproterenol results in increased expression of LRRC58 mRNA CTD PMID:20003209 NCBI chr11:62,850,507...62,862,829
Ensembl chr11:62,847,562...62,862,829
JBrowse link
G Lrrc8c leucine rich repeat containing 8 VRAC subunit C increases expression ISO Isoproterenol results in increased expression of LRRC8C mRNA CTD PMID:20003209 NCBI chr14:4,223,901...4,315,590
Ensembl chr14:4,227,832...4,315,249
JBrowse link
G Lsm14a LSM14A mRNA processing body assembly factor increases expression ISO Isoproterenol results in increased expression of LSM14A mRNA CTD PMID:20003209 NCBI chr 1:86,964,800...87,009,325
Ensembl chr 1:86,964,828...87,009,276
JBrowse link
G Lsm3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression ISO Isoproterenol results in decreased expression of LSM3 mRNA CTD PMID:20003209 NCBI chr 4:124,021,023...124,027,269
Ensembl chr 4:124,021,023...124,027,269
JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 increases expression
increases expression
ISO Isoproterenol results in increased expression of LTBP2 mRNA
Isoproterenol increases expression of Ltbp2 mRNA in the heart
CTD
RGD
PMID:20003209 PMID:29950403 RGD:156451654 NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208
JBrowse link
G Ly6a lymphocyte antigen 6 family member A increases expression ISO Isoproterenol results in increased expression of LY6A mRNA CTD PMID:20003209 NCBI chr 7:107,177,191...107,189,436
Ensembl chr 7:107,183,469...107,189,981
JBrowse link
G Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 increases expression ISO Isoproterenol results in increased expression of LYVE1 mRNA CTD PMID:20003209 NCBI chr 1:164,962,872...164,976,309
Ensembl chr 1:164,962,872...164,976,309
JBrowse link
G Maf MAF bZIP transcription factor increases expression EXP Isoproterenol results in increased expression of MAF mRNA CTD PMID:30303030 NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Isoproterenol results in increased expression of MAFF mRNA CTD PMID:20003209 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Man1a1 mannosidase, alpha, class 1A, member 1 increases expression ISO Isoproterenol results in increased expression of MAN1A mRNA CTD PMID:20003209 NCBI chr20:33,202,509...33,385,747
Ensembl chr20:33,202,517...33,385,824
JBrowse link
G Man2a1 mannosidase, alpha, class 2A, member 1 increases expression ISO Isoproterenol results in increased expression of MAN2A1 mRNA CTD PMID:20003209 NCBI chr 9:104,252,001...104,408,349
Ensembl chr 9:104,252,001...104,408,349
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions EXP
ISO
MAP2K1 protein affects the reaction [Isoproterenol results in increased expression of NPPA mRNA]; MAP2K1 protein affects the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; MAP2K1 protein affects the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK3 protein]
MAP2K1 protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; MAP2K1 protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; MAP2K1 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; MAP2K1 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]
CTD PMID:10888249 PMID:21177286 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of MAP2K4 mRNA CTD PMID:30303030 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Map3k2 mitogen activated protein kinase kinase kinase 2 multiple interactions
decreases expression
EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of MAP3K2 mRNA
Isoproterenol results in decreased expression of MAP3K2 mRNA
CTD PMID:30303030 NCBI chr18:23,807,218...23,879,722
Ensembl chr18:23,807,218...23,871,433
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 decreases expression ISO Isoproterenol results in decreased expression of MAP3K5 mRNA CTD PMID:21335049 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Map3k6 mitogen-activated protein kinase kinase kinase 6 multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of MAP3K6 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 5:145,440,126...145,452,213
Ensembl chr 5:145,440,346...145,452,212
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of MAP3K8 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216
JBrowse link
G Map7 microtubule-associated protein 7 increases expression ISO Isoproterenol results in increased expression of MAP7 mRNA CTD PMID:20003209 NCBI chr 1:14,910,433...15,037,574
Ensembl chr 1:14,910,551...15,037,574
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases activity
multiple interactions
increases phosphorylation
ISO
EXP
Isoproterenol results in increased activity of MAPK1 protein
[Isoproterenol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein; ARRB2 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; Isoproterenol inhibits the reaction [Estradiol results in decreased phosphorylation of MAPK1 protein]
erdosteine inhibits the reaction [Isoproterenol results in increased expression of and results in increased phosphorylation of MAPK1 protein]; Isoproterenol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Isoproterenol results in increased expression of and results in increased phosphorylation of MAPK1 protein; Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK1 protein; MAP2K1 protein affects the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of MAPK1 protein]; SL 327 inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]
DUSP1 protein inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; MAP2K1 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]
CTD PMID:10888249 PMID:11093795 PMID:15292328 PMID:16980553 PMID:17623046 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions
increases phosphorylation
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK14 protein] CTD PMID:18089841 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases activity
increases phosphorylation
increases expression
ISO
EXP
[Isoproterenol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein; ARRB2 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]; Isoproterenol inhibits the reaction [Estradiol results in decreased phosphorylation of MAPK3 protein]
Isoproterenol results in increased activity of MAPK3 protein
erdosteine inhibits the reaction [Isoproterenol results in increased expression of and results in increased phosphorylation of MAPK3 protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of MAPK3 mRNA]; geraniol inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]; Isoproterenol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; Isoproterenol results in increased expression of and results in increased phosphorylation of MAPK3 protein; Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK3 protein; MAP2K1 protein affects the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of MAPK3 protein]; SL 327 inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]
DUSP1 protein inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]; MAP2K1 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]
CTD PMID:10888249 PMID:11093795 PMID:15292328 PMID:16980553 PMID:17623046 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
increases activity
increases expression
ISO
EXP
candesartan inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein]
2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of MAPK8 mRNA]; geraniol inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein]
Isoproterenol results in increased activity of MAPK8 protein
CTD PMID:10591028 PMID:15951400 PMID:20562518 PMID:35608392 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 increases expression ISO Isoproterenol results in increased expression of MARCHF7 mRNA CTD PMID:20003209 NCBI chr 3:44,680,229...44,720,172
Ensembl chr 3:44,681,632...44,720,168
JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor decreases expression EXP Isoproterenol results in decreased expression of MAS1 protein CTD PMID:20409916 NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709
JBrowse link
G Mb myoglobin increases expression
increases secretion
multiple interactions
EXP Isoproterenol results in increased expression of MB protein
Isoproterenol results in increased secretion of MB protein
sinapinic acid inhibits the reaction [Isoproterenol results in increased expression of MB protein]
CTD PMID:533011 PMID:19628585 PMID:32627257 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383
JBrowse link
G Mbd1 methyl-CpG binding domain protein 1 increases expression ISO Isoproterenol results in increased expression of MBD1 mRNA CTD PMID:20003209 NCBI chr18:67,869,870...67,884,501
Ensembl chr18:67,869,992...67,886,554
JBrowse link
G Mbd5 methyl-CpG binding domain protein 5 increases expression ISO Isoproterenol results in increased expression of MBD5 mRNA CTD PMID:20003209 NCBI chr 3:33,588,854...33,738,730
Ensembl chr 3:33,333,554...33,730,156
JBrowse link
G Mccc2 methylcrotonyl-CoA carboxylase subunit 2 decreases expression ISO Isoproterenol results in decreased expression of MCCC2 mRNA CTD PMID:20003209 NCBI chr 2:31,304,927...31,375,978
Ensembl chr 2:31,304,932...31,375,972
JBrowse link
G Mcf2l MCF.2 cell line derived transforming sequence-like increases expression ISO Isoproterenol results in increased expression of MCF2L mRNA CTD PMID:20003209 NCBI chr16:76,507,133...76,652,893
Ensembl chr16:76,507,133...76,652,733
JBrowse link
G Mdga1 MAM domain containing glycosylphosphatidylinositol anchor 1 decreases expression ISO Isoproterenol results in decreased expression of MDGA1 mRNA CTD PMID:20003209 NCBI chr20:7,900,327...7,964,309
Ensembl chr20:7,904,358...7,963,471
JBrowse link
G Mef2c myocyte enhancer factor 2C decreases expression
increases expression
ISO
EXP
Isoproterenol results in decreased expression of MEF2C mRNA
Isoproterenol results in increased expression of MEF2C mRNA
CTD PMID:20003209 PMID:30303030 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Meig1 meiosis/spermiogenesis associated 1 decreases expression ISO Isoproterenol results in decreased expression of MEIG1 mRNA CTD PMID:20003209 NCBI chr17:74,810,791...74,828,433
Ensembl chr17:74,814,632...74,828,433
JBrowse link
G Metrn meteorin, glial cell differentiation regulator decreases expression ISO Isoproterenol results in decreased expression of METRN mRNA CTD PMID:20003209 NCBI chr10:14,816,684...14,818,702
Ensembl chr10:14,816,572...14,818,701
JBrowse link
G Mfap5 microfibril associated protein 5 increases expression ISO Isoproterenol results in increased expression of MFAP5 mRNA CTD PMID:20003209 NCBI chr 4:155,727,925...155,750,458
Ensembl chr 4:155,727,925...155,750,458
JBrowse link
G Mfn1 mitofusin 1 decreases expression EXP Isoproterenol results in decreased expression of MFN1 protein CTD PMID:27491814 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
JBrowse link
G Mfn2 mitofusin 2 decreases expression EXP Isoproterenol results in decreased expression of MFN2 protein CTD PMID:26692091 PMID:27491814 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mgll monoglyceride lipase decreases expression ISO Isoproterenol results in decreased expression of MGLL mRNA CTD PMID:20003209 NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179
JBrowse link
G Mgp matrix Gla protein increases expression ISO Isoproterenol results in increased expression of MGP mRNA CTD PMID:20003209 NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO Isoproterenol results in increased expression of MGST1 mRNA CTD PMID:20003209 PMID:21335049 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Miat myocardial infarction associated transcript increases expression
multiple interactions
EXP Isoproterenol results in increased expression of MIAT
Lutein inhibits the reaction [Isoproterenol results in increased expression of MIAT]
CTD PMID:34435724 NCBI chr12:44,414,620...44,429,852 JBrowse link
G Mib1 MIB E3 ubiquitin protein ligase 1 increases expression ISO Isoproterenol results in increased expression of MIB1 mRNA CTD PMID:20003209 NCBI chr18:1,802,519...1,926,988
Ensembl chr18:1,802,519...1,920,689
JBrowse link
G Mir122 microRNA 122 multiple interactions
increases expression
EXP xanthone inhibits the reaction [Isoproterenol results in increased expression of MIR122 mRNA] CTD PMID:36414029 NCBI chr18:58,758,703...58,758,787 JBrowse link
G Mir133a1 microRNA 133a-1 decreases expression ISO Isoproterenol results in decreased expression of MIR133A1 CTD PMID:19893015 NCBI chr18:1,885,082...1,885,168 JBrowse link
G Mir142 microRNA 142 increases expression EXP Isoproterenol results in increased expression of MIR142 mRNA CTD PMID:29355689 NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967
JBrowse link
G Mir145 microRNA 145 increases expression ISO isoprenaline increases expression of miRNA145 RNA in left ventricular myocardial tissues RGD PMID:35139769 RGD:155260312 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
JBrowse link
G Mir155 microRNA 155 increases expression EXP Isoproterenol results in increased expression of MIR155 mRNA CTD PMID:29355689 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir19a microRNA 19a increases expression EXP Isoproterenol results in increased expression of MIR19A mRNA CTD PMID:29355689 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993
JBrowse link
G Mir200a microRNA 200a multiple interactions
decreases expression
EXP Lutein inhibits the reaction [Isoproterenol results in decreased expression of MIR200A mRNA] CTD PMID:34435724 NCBI chr 5:166,648,494...166,648,582 JBrowse link
G Mir208a microRNA 208a increases expression
decreases expression
EXP Isoproterenol results in increased expression of MIR208A
Isoproterenol results in decreased expression of MIR208A mRNA
CTD PMID:26454886 PMID:29355689 NCBI chr15:28,425,570...28,425,652 JBrowse link
G Mir208b microRNA 208b increases expression EXP Isoproterenol results in increased expression of MIR208B mRNA CTD PMID:29355689 NCBI chr15:28,451,638...28,451,749
Ensembl chr15:28,451,638...28,451,749
JBrowse link
G Mir21 microRNA 21 increases expression EXP Isoproterenol results in increased expression of MIR21 mRNA CTD PMID:28526319 PMID:29355689 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir214 microRNA 214 multiple interactions
increases expression
EXP MIR214 mRNA promotes the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased expression of COL3A1 mRNA]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]
Isoproterenol results in increased expression of MIR214 mRNA
CTD PMID:26692091 NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481
JBrowse link
G Mir30e microRNA 30e decreases expression EXP Isoproterenol decreases expression of Mir30e mRNA in the heart RGD PMID:28777253 RGD:401827856 NCBI chr 5:134,352,232...134,352,323
Ensembl chr 5:134,352,232...134,352,323
JBrowse link
G Mix23 mitochondrial matrix import factor 23 decreases expression ISO Isoproterenol results in decreased expression of MIX23 mRNA CTD PMID:20003209 NCBI chr11:64,660,711...64,681,000
Ensembl chr11:64,660,711...64,681,000
JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 increases expression ISO Isoproterenol results in increased expression of MKNK2 mRNA CTD PMID:20003209 NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827
JBrowse link
G Mlf1 myeloid leukemia factor 1 decreases expression ISO Isoproterenol results in decreased expression of MLF1 mRNA CTD PMID:20003209 NCBI chr 2:151,648,492...151,681,654
Ensembl chr 2:151,648,511...151,681,652
JBrowse link
G Mlh1 mutL homolog 1 increases expression ISO Isoproterenol results in increased expression of MLH1 mRNA CTD PMID:21335049 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Mmd monocyte to macrophage differentiation-associated decreases expression ISO Isoproterenol results in decreased expression of MMD mRNA CTD PMID:20003209 NCBI chr10:75,073,278...75,101,528
Ensembl chr10:75,073,365...75,101,528
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression
multiple interactions
EXP Isoproterenol results in increased expression of MMP1
SI 27 inhibits the reaction [Isoproterenol results in increased expression of MMP1]
CTD PMID:12883319 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp11 matrix metallopeptidase 11 increases expression ISO Isoproterenol results in increased expression of MMP11 mRNA CTD PMID:20003209 NCBI chr20:12,730,846...12,739,629
Ensembl chr20:12,730,836...12,739,628
JBrowse link
G Mmp14 matrix metallopeptidase 14 increases expression ISO Isoproterenol results in increased expression of MMP14 mRNA CTD PMID:21335049 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Mmp15 matrix metallopeptidase 15 decreases expression ISO Isoproterenol results in decreased expression of MMP15 mRNA CTD PMID:20003209 NCBI chr19:9,663,449...9,684,943
Ensembl chr19:9,663,449...9,684,943
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
increases activity
ISO
EXP
Doxycycline inhibits the reaction [Isoproterenol results in increased activity of MMP2]; Isoproterenol results in increased expression of and results in increased activity of MMP2 protein
Isoproterenol results in increased expression of MMP2 mRNA; Isoproterenol results in increased expression of MMP2 protein
geraniol inhibits the reaction [Isoproterenol results in increased expression of MMP2 mRNA]
CTD PMID:16327176 PMID:18089841 PMID:24929186 PMID:35608392 PMID:37016276 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions
increases expression
ISO
EXP
Doxycycline inhibits the reaction [Isoproterenol results in increased expression of MMP3 mRNA]
SI 27 inhibits the reaction [Isoproterenol results in increased expression of MMP3]
CTD PMID:12883319 PMID:18089841 PMID:20003209 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases activity
increases expression
ISO
EXP
Propranolol inhibits the reaction [Isoproterenol results in increased expression of MMP9 mRNA]
Doxycycline inhibits the reaction [Isoproterenol results in increased activity of MMP9]
CPU0213 inhibits the reaction [Isoproterenol results in increased expression of MMP9 mRNA]; geraniol inhibits the reaction [Isoproterenol results in increased expression of MMP9 mRNA]; pimagedine inhibits the reaction [Isoproterenol results in increased expression of MMP9 mRNA]
CTD PMID:16574429 PMID:18089841 PMID:18594475 PMID:24929186 PMID:35608392 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mmrn1 multimerin 1 increases expression ISO Isoproterenol results in increased expression of MMRN1 mRNA CTD PMID:20003209 NCBI chr 4:89,875,408...89,950,814
Ensembl chr 4:89,903,174...89,950,474
JBrowse link
G Mospd2 motile sperm domain containing 2 increases expression ISO Isoproterenol results in increased expression of MOSPD2 mRNA CTD PMID:20003209 NCBI chr  X:29,420,485...29,472,099
Ensembl chr  X:29,420,586...29,462,398
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
increases expression
EXP caffeic acid phenethyl ester inhibits the reaction [Isoproterenol results in increased activity of MPO protein]; Glyburide promotes the reaction [Isoproterenol results in increased activity of MPO protein]; pyrvinium inhibits the reaction [Isoproterenol results in increased activity of MPO protein]; sodium thiosulfate inhibits the reaction [Isoproterenol results in increased activity of MPO protein]
Isoproterenol results in increased expression of MPO protein
CTD PMID:20693123 PMID:32865837 PMID:35014750 PMID:35305975 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mpp7 MAGUK p55 scaffold protein 7 increases expression ISO Isoproterenol results in increased expression of MPP7 mRNA CTD PMID:20003209 NCBI chr17:55,439,939...55,706,810
Ensembl chr17:55,442,696...55,706,748
JBrowse link
G Mrc1 mannose receptor, C type 1 increases expression ISO Isoproterenol results in increased expression of MRC1 mRNA CTD PMID:20003209 NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857
JBrowse link
G Mrpl41 mitochondrial ribosomal protein L41 decreases expression ISO Isoproterenol results in decreased expression of MRPL41 mRNA CTD PMID:20003209 NCBI chr 3:7,780,658...7,781,576
Ensembl chr 3:7,779,143...7,782,818
JBrowse link
G Mrpl45 mitochondrial ribosomal protein L45 decreases expression ISO Isoproterenol results in decreased expression of MRPL45 mRNA CTD PMID:20003209 NCBI chr10:82,308,650...82,320,474
Ensembl chr10:82,308,427...82,320,474
JBrowse link
G Msr1 macrophage scavenger receptor 1 increases expression ISO Isoproterenol results in increased expression of MSR1 mRNA CTD PMID:20003209 NCBI chr16:52,717,775...52,803,602
Ensembl chr16:52,717,732...52,799,676
JBrowse link
G Mt1 metallothionein 1 increases expression ISO Isoproterenol results in increased expression of MT1 mRNA CTD PMID:20003209 PMID:21335049 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
JBrowse link
G Mt2A metallothionein 2A multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of MT2 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mtch2 mitochondrial carrier 2 increases expression ISO Isoproterenol results in increased expression of MTCH2 mRNA CTD PMID:20003209 NCBI chr 3:76,830,549...76,850,189
Ensembl chr 3:76,830,413...76,850,189
JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation
multiple interactions
EXP Isoproterenol results in increased phosphorylation of MTOR protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Isoproterenol results in increased phosphorylation of MTOR protein]; Sirolimus inhibits the reaction [Isoproterenol results in increased phosphorylation of MTOR protein]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased phosphorylation of MTOR protein]]
CTD PMID:17623046 PMID:25045214 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 decreases expression ISO Isoproterenol results in decreased expression of MTSS1 mRNA CTD PMID:20003209 NCBI chr 7:90,488,751...90,628,007
Ensembl chr 7:90,488,754...90,627,968
JBrowse link
G Mustn1 musculoskeletal, embryonic nuclear protein 1 increases expression ISO Isoproterenol results in increased expression of MUSTN1 mRNA CTD PMID:20003209 NCBI chr16:6,072,908...6,075,161
Ensembl chr16:6,072,833...6,075,161
JBrowse link
G Mybpc3 myosin binding protein C3 multiple interactions
affects response to substance
ISO MYBPC3 gene mutant form results in increased susceptibility to [Isoproterenol co-treated with Phenylephrine]
MYBPC3 mutant form results in increased susceptibility to [Isoproterenol co-treated with Phenylephrine]
MYBPC3 protein affects the susceptibility to Isoproterenol
CTD PMID:22076249 PMID:23896226 NCBI chr 3:77,095,165...77,113,406
Ensembl chr 3:77,095,252...77,113,405
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression EXP
ISO
Isoproterenol results in increased expression of MYC mRNA CTD PMID:20003209 PMID:20211217 PMID:21823215 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor decreases expression ISO Isoproterenol results in decreased expression of MYCN mRNA CTD PMID:20003209 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor increases expression
multiple interactions
EXP Isoproterenol results in increased expression of MYD88 mRNA; Isoproterenol results in increased expression of MYD88 protein
anethole inhibits the reaction [Isoproterenol results in increased expression of MYD88 mRNA]; anethole inhibits the reaction [Isoproterenol results in increased expression of MYD88 protein]; Metformin inhibits the reaction [Isoproterenol results in increased expression of MYD88 mRNA]
CTD PMID:24842192 PMID:35430261 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Myh6 myosin heavy chain 6 increases expression
multiple interactions
ISO Isoproterenol results in increased expression of MYH6 protein
plantamajoside inhibits the reaction [Isoproterenol results in increased expression of MYH6 protein]; PPARA protein promotes the reaction [celastrol methyl ester inhibits the reaction [Isoproterenol results in decreased expression of MYH6 mRNA]]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of MYH6 protein]
CTD PMID:31009642 PMID:37269933 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720
JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions
increases expression
ISO
EXP
[Phenylephrine co-treated with Isoproterenol] results in increased expression of MYH7 mRNA; bellidifolin inhibits the reaction [Isoproterenol results in increased expression of MYH7 protein]; Doxycycline inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]
Isoproterenol results in increased expression of MYH7 mRNA; Isoproterenol results in increased expression of MYH7 protein
bellidifolin inhibits the reaction [Isoproterenol results in increased expression of MYH7 protein]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of MYH7 protein]; Isoproterenol inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of MYH7 protein]; RELA mRNA promotes the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]]
CTD PMID:10710348 PMID:18089841 PMID:18851973 PMID:25045214 PMID:28816235 More... NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217
JBrowse link
G Myh7b myosin heavy chain 7B decreases expression ISO Isoproterenol results in decreased expression of MYH7B mRNA CTD PMID:20003209 NCBI chr 3:144,076,911...144,122,714
Ensembl chr 3:144,098,190...144,122,084
JBrowse link
G Myl1 myosin, light chain 1 increases expression EXP Isoproterenol results in increased expression of MYL1 protein CTD PMID:19854236 NCBI chr 9:68,437,514...68,458,256
Ensembl chr 9:68,437,517...68,458,261
JBrowse link
G Myl3 myosin light chain 3 increases expression EXP Isoproterenol results in increased expression of MYL3 protein CTD PMID:24286936 NCBI chr 8:110,738,669...110,744,814
Ensembl chr 8:110,738,661...110,744,816
JBrowse link
G Mylip myosin regulatory light chain interacting protein increases expression ISO Isoproterenol results in increased expression of MYLIP mRNA CTD PMID:20003209 NCBI chr17:19,286,649...19,308,295
Ensembl chr17:19,286,650...19,308,295
JBrowse link
G Myo5a myosin VA increases expression ISO Isoproterenol results in increased expression of MYO5A mRNA CTD PMID:20003209 NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918
JBrowse link
G Myot myotilin increases expression ISO Isoproterenol results in increased expression of MYOT mRNA CTD PMID:20003209 NCBI chr18:36,705,244...36,724,849
Ensembl chr18:36,705,314...36,724,841
JBrowse link
G Myrip myosin VIIA and Rab interacting protein increases expression ISO Isoproterenol results in increased expression of MYRIP mRNA CTD PMID:20003209 NCBI chr 8:120,017,749...120,184,821
Ensembl chr 8:120,017,524...120,183,833
JBrowse link
G N4bp2l1 NEDD4 binding protein 2-like 1 increases expression ISO Isoproterenol results in increased expression of N4BP2L1 mRNA CTD PMID:20003209 NCBI chr12:102,572...128,352
Ensembl chr12:102,573...127,257
JBrowse link
G Nab1 Ngfi-A binding protein 1 multiple interactions ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of NAB1 mRNA CTD PMID:10710348 NCBI chr 9:49,053,579...49,093,078
Ensembl chr 9:49,053,758...49,092,098
JBrowse link
G Nab2 Ngfi-A binding protein 2 multiple interactions ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of NAB2 mRNA; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NAB2 mRNA] CTD PMID:10710348 NCBI chr 7:63,497,589...63,504,105
Ensembl chr 7:63,497,589...63,503,989
JBrowse link
G Nabp1 nucleic acid binding protein 1 decreases expression ISO Isoproterenol results in decreased expression of NABP1 mRNA CTD PMID:20003209 NCBI chr 9:50,098,552...50,133,982
Ensembl chr 9:50,126,726...50,134,107
JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase multiple interactions
increases activity
EXP Phytic Acid inhibits the reaction [Isoproterenol results in increased activity of NAGLU protein] CTD PMID:25560919 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972
JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 increases expression ISO Isoproterenol results in increased expression of NARS1 mRNA CTD PMID:21335049 NCBI chr18:57,989,308...58,005,584
Ensembl chr18:57,989,308...58,005,622
JBrowse link
G Nbn nibrin decreases expression
increases expression
ISO Isoproterenol results in decreased expression of NBN mRNA
Isoproterenol results in increased expression of NBN mRNA
CTD PMID:21335049 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions
increases expression
EXP CPU0213 inhibits the reaction [Isoproterenol results in increased expression of NCF1 mRNA] CTD PMID:18594475 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 multiple interactions
increases expression
EXP 1-(methanesulfonamido-1-naphthyloxy)-2-(N-(4-methane sulfonamidophenethyl)-N-acetamido)ethane inhibits the reaction [Isoproterenol results in increased expression of NCF2 mRNA]; 1-(methanesulfonamido-1-naphthyloxy)-2-(N-(4-methane sulfonamidophenethyl)-N-acetamido)ethane inhibits the reaction [Isoproterenol results in increased expression of NCF2 protein]; dofetilide inhibits the reaction [Isoproterenol results in increased expression of NCF2 mRNA]; dofetilide inhibits the reaction [Isoproterenol results in increased expression of NCF2 protein]
Isoproterenol results in increased expression of NCF2 mRNA; Isoproterenol results in increased expression of NCF2 protein
CTD PMID:20723002 NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277
JBrowse link
G Ncstn nicastrin increases expression
multiple interactions
EXP Isoproterenol results in increased expression of NCSTN mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of NCSTN mRNA
CTD PMID:30303030 NCBI chr13:84,530,442...84,546,454
Ensembl chr13:84,530,440...84,546,454
JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression ISO Isoproterenol results in increased expression of NDRG1 mRNA CTD PMID:20003209 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Ndufa10l1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10-like 1 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFA10L1 mRNA CTD PMID:30303030 NCBI chr 6:59,879,819...59,881,252
Ensembl chr 6:59,879,312...59,881,241
JBrowse link
G Ndufa11 NADH:ubiquinone oxidoreductase subunit A11 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFA11 mRNA CTD PMID:30303030 NCBI chr 9:1,550,487...1,554,546
Ensembl chr 9:1,550,468...1,555,601
JBrowse link
G Ndufa2 NADH:ubiquinone oxidoreductase subunit A2 decreases expression EXP Isoproterenol results in decreased expression of NDUFA2 mRNA CTD PMID:30303030 NCBI chr18:28,355,774...28,357,863
Ensembl chr18:28,355,774...28,358,076
JBrowse link
G Ndufb2 NADH:ubiquinone oxidoreductase subunit B2 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFB2 mRNA CTD PMID:30303030 NCBI chr 4:68,367,526...68,374,609
Ensembl chr15:46,536,062...46,536,851
Ensembl chr 4:46,536,062...46,536,851
JBrowse link
G Ndufb5 NADH:ubiquinone oxidoreductase subunit B5 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFB5 mRNA CTD PMID:30303030 NCBI chr 2:115,519,248...115,533,589
Ensembl chr 2:115,519,154...115,533,589
JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFB8 mRNA CTD PMID:30303030 NCBI chr 1:243,408,656...243,413,715
Ensembl chr 1:243,408,619...243,413,817
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFS1 mRNA CTD PMID:30303030 NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893
JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFS3 mRNA CTD PMID:30303030 NCBI chr 3:76,876,646...76,883,824
Ensembl chr 3:76,876,646...76,883,824
JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFS4 mRNA CTD PMID:30303030 NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846
JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFS8 mRNA CTD PMID:30303030 NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511
JBrowse link
G Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFV1 mRNA CTD PMID:30303030 NCBI chr 1:201,300,365...201,305,461
Ensembl chr 1:201,299,985...201,305,466
JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFV2 mRNA CTD PMID:30303030 NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:105,690,455...105,710,713
JBrowse link
G Neb nebulin increases expression ISO Isoproterenol results in increased expression of NEB mRNA CTD PMID:20003209 NCBI chr 3:36,613,677...36,811,618
Ensembl chr 3:36,613,716...36,811,574
JBrowse link
G Nes nestin decreases expression ISO Isoproterenol results in decreased expression of NES mRNA CTD PMID:20003209 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 affects localization
multiple interactions
EXP Isoproterenol affects the localization of NFATC1 protein
Cyclosporine inhibits the reaction [Isoproterenol affects the localization of NFATC1 protein]; Isoproterenol promotes the reaction [NFATC1 protein binds to GATA4 protein]
CTD PMID:11435416 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases expression
multiple interactions
increases expression
EXP Isoproterenol results in decreased expression of NFE2L2 mRNA; Isoproterenol results in decreased expression of NFE2L2 protein
[erdosteine co-treated with Isoproterenol] results in increased expression of NFE2L2 protein; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NFE2L2 mRNA; anethole promotes the reaction [Isoproterenol results in increased expression of NFE2L2 mRNA]; anethole promotes the reaction [Isoproterenol results in increased expression of NFE2L2 protein]; Lutein inhibits the reaction [Isoproterenol results in decreased expression of NFE2L2 protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in decreased expression of NFE2L2 mRNA]; punicalagin inhibits the reaction [Isoproterenol results in decreased expression of NFE2L2 protein]; Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in decreased expression of NFE2L2 mRNA]
Isoproterenol results in increased expression of NFE2L2 mRNA; Isoproterenol results in increased expression of NFE2L2 protein
CTD PMID:28266775 PMID:30303030 PMID:32007421 PMID:33210414 PMID:34435724 More... NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfic nuclear factor I/C decreases expression ISO Isoproterenol results in decreased expression of NFIC mRNA CTD PMID:20003209 NCBI chr 7:8,278,210...8,309,936
Ensembl chr 7:8,253,361...8,309,936
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated increases expression ISO Isoproterenol results in increased expression of NFIL3 mRNA CTD PMID:20003209 NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases activity
increases expression
ISO
EXP
Isoproterenol results in increased activity of [NFKB1 protein binds to RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased activity of [NFKB1 protein binds to RELA protein]]
Isoproterenol results in increased activity of NFKB1 protein
[Isoproterenol co-treated with POSTN protein] results in decreased expression of NFKB1 mRNA
Isoproterenol results in increased expression of NFKB1 mRNA
CTD PMID:15178407 PMID:18487443 PMID:30303030 PMID:35014750 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression
multiple interactions
decreases expression
increases degradation
ISO
EXP
Isoproterenol results in increased expression of NFKBIA mRNA
Isoproterenol results in increased phosphorylation of and results in increased degradation of NFKBIA protein
Isoproterenol results in decreased expression of NFKBIA protein
Isoproterenol results in decreased expression of NFKBIA mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of NFKBIA mRNA; Isoproterenol promotes the reaction [G3BP2 protein binds to NFKBIA protein]; Sirolimus inhibits the reaction [Isoproterenol results in increased degradation of NFKBIA protein]
CTD PMID:15178407 PMID:18487443 PMID:20003209 PMID:21335049 PMID:25045214 More... NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbiz NFKB inhibitor zeta increases expression ISO Isoproterenol results in increased expression of NFKBIZ mRNA CTD PMID:20003209 NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723
JBrowse link
G Ngf nerve growth factor increases expression
multiple interactions
EXP Isoproterenol results in increased expression of NGF mRNA
[Isoproterenol results in increased abundance of Cyclic AMP] which results in increased expression of NGF mRNA; Propranolol inhibits the reaction [Isoproterenol results in increased expression of NGF mRNA]
CTD PMID:2174743 PMID:2853697 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nherf4 NHERF family PDZ scaffold protein 4 decreases expression ISO Isoproterenol results in decreased expression of NHERF4 mRNA CTD PMID:20003209 NCBI chr 8:44,584,390...44,588,838
Ensembl chr 8:44,584,390...44,588,860
JBrowse link
G Ninj1 ninjurin 1 increases expression ISO Isoproterenol results in increased expression of NINJ1 mRNA CTD PMID:20003209 NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704
JBrowse link
G Nkiras2 NFKB inhibitor interacting Ras-like 2 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of NKIRAS2 mRNA CTD PMID:30303030 NCBI chr10:85,554,704...85,562,072
Ensembl chr10:85,557,944...85,562,072
JBrowse link
G Nkx2-5 NK2 homeobox 5 multiple interactions ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of NKX2-5 mRNA CTD PMID:10710348 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934
JBrowse link
G Nme6 NME/NM23 nucleoside diphosphate kinase 6 increases expression ISO Isoproterenol results in increased expression of NME6 mRNA CTD PMID:21335049 NCBI chr 8:109,832,085...109,839,301
Ensembl chr 8:109,832,589...109,839,301
JBrowse link
G Nmrk2 nicotinamide riboside kinase 2 decreases expression ISO Isoproterenol results in decreased expression of NMRK2 mRNA CTD PMID:20003209 NCBI chr 7:8,514,855...8,517,916
Ensembl chr 7:8,514,927...8,517,922
JBrowse link
G Noct nocturnin increases expression ISO Isoproterenol results in increased expression of NOCT mRNA CTD PMID:20003209 NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400
JBrowse link
G Nol3 nucleolar protein 3 decreases phosphorylation EXP Isoproterenol results in decreased phosphorylation of NOL3 protein CTD PMID:19001025 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Nos1 nitric oxide synthase 1 increases expression
decreases expression
multiple interactions
EXP Isoproterenol results in increased expression of NOS1 protein
Isoproterenol results in decreased expression of NOS1 protein
thymoquinone inhibits the reaction [Isoproterenol results in decreased expression of NOS1 protein]
CTD PMID:16702995 PMID:35940283 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression
multiple interactions
increases expression
ISO
EXP
Isoproterenol results in decreased expression of NOS2 mRNA
[Isoproterenol results in increased expression of NOS2] which results in increased chemical synthesis of Nitric Oxide; Apigenin inhibits the reaction [Isoproterenol results in increased expression of NOS2 protein]; Ascorbic Acid inhibits the reaction [Isoproterenol results in increased expression of NOS2 protein]; caryophyllene inhibits the reaction [Isoproterenol results in increased expression of NOS2 protein]; N-(1-methylethyl)-1,1,2-trimethylpropylamine inhibits the reaction [Isoproterenol results in increased expression of NOS2 mRNA]; natakalim inhibits the reaction [[Isoproterenol results in increased expression of NOS2] which results in increased chemical synthesis of Nitric Oxide]; natakalim inhibits the reaction [Isoproterenol results in increased expression of NOS2 mRNA]; natakalim inhibits the reaction [Isoproterenol results in increased expression of NOS2]; pimagedine inhibits the reaction [Isoproterenol results in increased expression of NOS2 mRNA]; punicalagin inhibits the reaction [Isoproterenol results in increased expression of NOS2 protein]; Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of NOS2 mRNA]; Tretinoin inhibits the reaction [Isoproterenol results in increased expression of NOS2 mRNA]
Isoproterenol results in increased expression of NOS2; Isoproterenol results in increased expression of NOS2 mRNA; Isoproterenol results in increased expression of NOS2 protein
CTD PMID:18594475 PMID:18816294 PMID:19168511 PMID:19466570 PMID:24286936 More... NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
affects response to substance
decreases expression
increases expression
decreases phosphorylation
EXP
ISO
3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [Isoproterenol affects the expression of NOS3 mRNA]; 3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [Isoproterenol affects the expression of NOS3 protein]; 5-Methoxypsoralen inhibits the reaction [Isoproterenol results in decreased phosphorylation of NOS3 protein]; [Isoproterenol co-treated with Caffeine] results in decreased expression of NOS3 mRNA; caryophyllene inhibits the reaction [Isoproterenol results in decreased expression of NOS3 protein]; N-(1-methylethyl)-1,1,2-trimethylpropylamine inhibits the reaction [Isoproterenol results in decreased expression of NOS3 mRNA]; natakalim inhibits the reaction [Isoproterenol results in decreased expression of NOS3 mRNA]; thymoquinone inhibits the reaction [Isoproterenol results in increased expression of NOS3 protein]
NOS3 inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]
NOS3 protein affects the susceptibility to Isoproterenol
Isoproterenol results in decreased expression of NOS3 mRNA; Isoproterenol results in decreased expression of NOS3 protein
Isoproterenol results in increased expression of NOS3 mRNA; Isoproterenol results in increased expression of NOS3 protein
CTD PMID:12224825 PMID:16702995 PMID:17403420 PMID:17996136 PMID:18816294 More... NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Notch1 notch receptor 1 decreases expression
multiple interactions
EXP Isoproterenol results in decreased expression of NOTCH1 mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of NOTCH1 mRNA
CTD PMID:30303030 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Notch4 notch receptor 4 increases expression ISO Isoproterenol results in increased expression of NOTCH4 mRNA CTD PMID:20003209 NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465
JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions
increases expression
ISO
EXP
bellidifolin inhibits the reaction [Isoproterenol results in increased expression of NOX4 mRNA]; bellidifolin inhibits the reaction [Isoproterenol results in increased expression of NOX4 protein]; Doxycycline inhibits the reaction [Isoproterenol results in increased expression of NOX4 mRNA]
Isoproterenol results in increased expression of NOX4 mRNA; Isoproterenol results in increased expression of NOX4 protein
CTD PMID:18089841 PMID:20003209 PMID:37528096 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Npm1 nucleophosmin 1 decreases expression ISO Isoproterenol results in decreased expression of NPM1 mRNA CTD PMID:21335049 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Npm3 nucleophosmin/nucleoplasmin, 3 decreases expression ISO Isoproterenol results in decreased expression of NPM3 mRNA CTD PMID:20003209 NCBI chr 1:244,595,638...244,597,623
Ensembl chr 1:244,595,644...244,597,591
JBrowse link
G Nppa natriuretic peptide A multiple interactions
decreases expression
increases expression
decreases secretion
increases expression
ISO
EXP
[Phenylephrine co-treated with Isoproterenol] results in increased expression of NPPA mRNA; bellidifolin inhibits the reaction [Isoproterenol results in increased expression of NPPA protein]; celastrol methyl ester inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NPPA mRNA]; NOS3 inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of NPPA protein]; PPARA protein promotes the reaction [celastrol methyl ester inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]]; swietenine inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of NPPA protein]
ADRB1 protein promotes the reaction [Isoproterenol results in decreased expression of NPPA protein]; Atorvastatin inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; bellidifolin inhibits the reaction [Isoproterenol results in increased expression of NPPA protein]; CREM protein inhibits the reaction [Isoproterenol results in increased expression of NPPA protein]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPA mRNA]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPA protein]; Isoproterenol inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; manidipine inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; MAP2K1 protein affects the reaction [Isoproterenol results in increased expression of NPPA mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPA protein]; RELA mRNA promotes the reaction [Isoproterenol results in increased expression of NPPA mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; Spironolactone inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; swietenine inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; thymoquinone inhibits the reaction [Isoproterenol results in decreased secretion of NPPA protein]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]
Isoproterenol results in increased expression of NPPA mRNA; Isoproterenol results in increased expression of NPPA protein
isoprenaline increases expression of mRNA in neonatal rat cardiomyocytes
CTD
RGD
PMID:8077211 PMID:9043801 PMID:9559417 PMID:10710348 PMID:10888249 More... RGD:11526363 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nppb natriuretic peptide B multiple interactions
increases expression
decreases secretion
increases expression
EXP
ISO
2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]; bellidifolin inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]; Enalapril inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPB mRNA]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPB protein]; Glyburide inhibits the reaction [natakalim inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]]; Glyburide inhibits the reaction [natakalim inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]]; N-(1-methylethyl)-1,1,2-trimethylpropylamine inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; N-(1-methylethyl)-1,1,2-trimethylpropylamine inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]; natakalim inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; natakalim inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]; RELA mRNA promotes the reaction [Isoproterenol results in increased expression of NPPB mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; swietenine inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; thymoquinone inhibits the reaction [Isoproterenol results in decreased secretion of NPPB protein modified form]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]]
Isoproterenol results in increased expression of NPPB mRNA; Isoproterenol results in increased expression of NPPB protein
bellidifolin inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]; celastrol methyl ester inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]; PPARA protein promotes the reaction [celastrol methyl ester inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]]; swietenine inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]
isoprenaline increases expression of mRNA in neonatal rat cardiomyocytes
CTD
RGD
PMID:9043801 PMID:11804996 PMID:18806606 PMID:25045214 PMID:27890915 More... RGD:11526363 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
multiple interactions
EXP Isoproterenol results in decreased expression of NQO1 mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of NQO1 mRNA
CTD PMID:30303030 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 decreases expression ISO Isoproterenol results in decreased expression of NQO2 mRNA CTD PMID:21335049 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression
increases expression
EXP Isoproterenol results in decreased expression of NR1H4 mRNA
Isoproterenol results in increased expression of NR1H4 mRNA
CTD PMID:24286936 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 decreases expression ISO Isoproterenol results in decreased expression of NR4A1 mRNA CTD PMID:20003209 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression ISO Isoproterenol results in increased expression of NR4A3 mRNA CTD PMID:34601065 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
JBrowse link
G Nsmaf neutral sphingomyelinase activation associated factor multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of NSMAF mRNA CTD PMID:30303030 NCBI chr 5:19,517,795...19,578,773
Ensembl chr 5:19,518,348...19,577,627
JBrowse link
G Ntf3 neurotrophin 3 decreases expression ISO Isoproterenol results in decreased expression of NTF3 mRNA CTD PMID:20003209 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596
JBrowse link
G Nucb2 nucleobindin 2 increases expression ISO Isoproterenol results in increased expression of NUCB2 mRNA CTD PMID:21823215 NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353
JBrowse link
G Nxt2 nuclear transport factor 2-like export factor 2 increases expression ISO Isoproterenol results in increased expression of NXT2 mRNA CTD PMID:20003209 NCBI chr  X:105,855,616...105,862,902
Ensembl chr  X:105,855,608...105,862,899
JBrowse link
G Oaz2 ornithine decarboxylase antizyme 2 decreases expression ISO Isoproterenol results in decreased expression of OAZ2 mRNA CTD PMID:20003209 NCBI chr 8:66,199,694...66,213,513
Ensembl chr 8:66,199,706...66,231,453
JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions
increases activity
ISO Propranolol inhibits the reaction [Isoproterenol results in increased activity of ODC1 protein] CTD PMID:6284819 PMID:10354516 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Oga O-GlcNAcase increases expression ISO Isoproterenol results in increased expression of OGA mRNA CTD PMID:20003209 NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359
JBrowse link
G Ogdh oxoglutarate dehydrogenase decreases expression
multiple interactions
decreases activity
EXP Isoproterenol results in decreased expression of OGDH mRNA
naringin inhibits the reaction [Isoproterenol results in decreased activity of OGDH protein]; S-allylcysteine inhibits the reaction [Isoproterenol results in decreased expression of OGDH mRNA]; sinapinic acid inhibits the reaction [Isoproterenol results in decreased activity of OGDH protein]; Thymol inhibits the reaction [Isoproterenol results in decreased activity of OGDH protein]
CTD PMID:9753871 PMID:17182065 PMID:17994577 PMID:26721194 PMID:32627257 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
JBrowse link
G Omd osteomodulin increases expression ISO Isoproterenol results in increased expression of OMD mRNA CTD PMID:20003209 NCBI chr17:15,060,217...15,068,441
Ensembl chr17:15,060,217...15,068,441
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase decreases expression EXP Isoproterenol results in decreased expression of OPA1 protein CTD PMID:27491814 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Osmr oncostatin M receptor multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of OSMR mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 2:55,907,119...55,961,373
Ensembl chr 2:55,907,132...55,961,262
JBrowse link
G Otub1 OTU deubiquitinase, ubiquitin aldehyde binding 1 decreases expression ISO Isoproterenol results in decreased expression of OTUB1 mRNA CTD PMID:20003209 NCBI chr 1:204,387,215...204,395,495
Ensembl chr 1:204,387,215...204,395,483
JBrowse link
G P3h2 prolyl 3-hydroxylase 2 increases expression ISO Isoproterenol results in increased expression of P3H2 mRNA CTD PMID:20003209 NCBI chr11:74,634,267...74,775,422
Ensembl chr11:74,634,267...74,775,421
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta increases expression ISO Isoproterenol results in increased expression of P4HB mRNA CTD PMID:21823215 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
JBrowse link
G Pacrg parkin coregulated increases expression ISO Isoproterenol results in increased expression of PACRG mRNA CTD PMID:20003209 NCBI chr 1:49,882,671...50,305,564
Ensembl chr 1:49,882,630...50,305,430
JBrowse link
G Palld palladin, cytoskeletal associated protein decreases expression ISO Isoproterenol results in decreased expression of PALLD mRNA CTD PMID:20003209 NCBI chr16:28,228,006...28,621,349
Ensembl chr16:27,981,354...28,621,337
JBrowse link
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 increases expression ISO Isoproterenol results in increased expression of PAPSS2 mRNA CTD PMID:20003209 NCBI chr 1:230,454,314...230,539,332
Ensembl chr 1:230,454,426...230,539,331
JBrowse link
G Paqr9 progestin and adipoQ receptor family member 9 decreases expression ISO Isoproterenol results in decreased expression of PAQR9 mRNA CTD PMID:20003209 NCBI chr 8:96,114,249...96,116,546 JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases expression
increases cleavage
multiple interactions
increases expression
ISO
EXP
Isoproterenol results in decreased expression of PARP1 protein
Isoproterenol results in increased cleavage of PARP1 protein
BMP10 protein inhibits the reaction [Isoproterenol results in increased cleavage of PARP1 protein]
Isoproterenol results in increased expression of PARP1 protein
erdosteine affects the reaction [Isoproterenol results in increased expression of PARP1 protein]
CTD PMID:29438734 PMID:31712309 PMID:33210414 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions
increases expression
ISO
EXP
[Isoproterenol co-treated with rosiglitazone] results in increased expression of PCK1 mRNA; Dexamethasone inhibits the reaction [Isoproterenol results in increased expression of PCK1 mRNA] CTD PMID:9518257 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pcmtd2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 increases expression ISO Isoproterenol results in increased expression of PCMTD2 mRNA CTD PMID:20003209 NCBI chr 3:168,960,312...168,979,504
Ensembl chr 3:168,960,305...168,979,497
JBrowse link
G Pde3b phosphodiesterase 3B multiple interactions EXP [PDE3B protein co-treated with AKT1 protein] inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein] CTD PMID:19167487 NCBI chr 1:168,606,762...168,770,078
Ensembl chr 1:168,607,022...168,769,334
JBrowse link
G Pde4a phosphodiesterase 4A decreases expression ISO Isoproterenol results in decreased expression of PDE4A mRNA CTD PMID:20003209 NCBI chr 8:19,690,816...19,753,538
Ensembl chr 8:19,703,290...19,751,961
JBrowse link
G Pde7a phosphodiesterase 7A increases expression ISO Isoproterenol results in increased expression of PDE7A mRNA CTD PMID:20003209 NCBI chr 2:101,714,767...101,806,853
Ensembl chr 2:101,718,444...101,806,681
JBrowse link
G Pdgfd platelet derived growth factor D increases expression ISO Isoproterenol results in increased expression of PDGFD mRNA CTD PMID:20003209 NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 increases expression ISO Isoproterenol results in increased expression of PDIA4 mRNA CTD PMID:21335049 PMID:21823215 NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 increases expression ISO Isoproterenol results in increased expression of PDIA6 mRNA CTD PMID:21823215 NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 increases expression ISO Isoproterenol results in increased expression of PDK1 mRNA CTD PMID:20003209 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
JBrowse link
G Pdxdc1 pyridoxal-dependent decarboxylase domain containing 1 decreases expression ISO Isoproterenol results in decreased expression of PDXDC1 mRNA CTD PMID:20003209 NCBI chr10:2,025,056...2,113,712
Ensembl chr10:2,025,360...2,113,520
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 multiple interactions
decreases expression
ISO
EXP
PEBP1 protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP]
[Isoproterenol co-treated with POSTN protein] results in decreased expression of PEBP1 mRNA
Isoproterenol results in decreased expression of PEBP1 mRNA
CTD PMID:26670611 PMID:30303030 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of PECR mRNA CTD PMID:30303030 NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511
JBrowse link
G Peg3 paternally expressed 3 increases expression ISO Isoproterenol results in increased expression of PEG3 mRNA CTD PMID:20003209 NCBI chr 1:67,097,874...67,124,692
Ensembl chr 1:67,097,904...67,124,671
JBrowse link
G Penk proenkephalin multiple interactions
increases expression
EXP Metoprolol inhibits the reaction [Isoproterenol results in increased expression of PENK mRNA]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of PENK mRNA]; Serotonin inhibits the reaction [Isoproterenol results in increased expression of PENK mRNA] CTD PMID:1363325 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
JBrowse link
G Per3 period circadian regulator 3 decreases expression ISO Isoproterenol results in decreased expression of PER3 mRNA CTD PMID:20003209 NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607
JBrowse link
G Pex12 peroxisomal biogenesis factor 12 increases expression ISO Isoproterenol results in increased expression of PEX12 mRNA CTD PMID:20003209 NCBI chr10:68,095,776...68,103,812
Ensembl chr10:68,095,776...68,099,428
JBrowse link
G Pex2 peroxisomal biogenesis factor 2 increases expression ISO Isoproterenol results in increased expression of PEX2 mRNA CTD PMID:21335049 NCBI chr 2:96,050,380...96,072,928
Ensembl chr 2:96,045,958...96,073,404
JBrowse link
G Pgm2l1 phosphoglucomutase 2-like 1 increases expression ISO Isoproterenol results in increased expression of PGM2L1 mRNA CTD PMID:20003209 NCBI chr 1:154,571,410...154,620,901
Ensembl chr 1:154,571,766...154,620,902
JBrowse link
G Phf3 PHD finger protein 3 increases expression ISO Isoproterenol results in increased expression of PHF3 mRNA CTD PMID:20003209 NCBI chr 9:33,063,855...33,136,013
Ensembl chr 9:33,063,857...33,135,994
JBrowse link
G Phka1 phosphorylase kinase regulatory subunit alpha 1 increases expression ISO Isoproterenol results in increased expression of PHKA1 mRNA CTD PMID:20003209 NCBI chr  X:67,601,302...67,738,504
Ensembl chr  X:67,601,302...67,738,455
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 decreases expression ISO Isoproterenol results in decreased expression of PHLDA1 mRNA CTD PMID:20003209 NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861
JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 decreases expression ISO Isoproterenol results in decreased expression of PHLDA3 mRNA CTD PMID:21335049 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335
JBrowse link
G Phyhd1 phytanoyl-CoA dioxygenase domain containing 1 increases expression ISO Isoproterenol results in increased expression of PHYHD1 mRNA CTD PMID:20003209 NCBI chr 3:13,535,670...13,553,797
Ensembl chr 3:13,540,056...13,553,797
JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein increases expression ISO Isoproterenol results in increased expression of PICALM mRNA CTD PMID:20003209 NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557
JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A increases expression ISO Isoproterenol results in increased expression of PIGA mRNA CTD PMID:21823215 NCBI chr  X:30,043,033...30,055,861
Ensembl chr  X:30,042,343...30,055,804
JBrowse link
G Pigb phosphatidylinositol glycan anchor biosynthesis, class B decreases expression ISO Isoproterenol results in decreased expression of PIGB mRNA CTD PMID:21823215 NCBI chr 8:73,751,756...73,775,679
Ensembl chr 8:73,751,798...73,775,679
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma multiple interactions
increases activity
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Isoproterenol results in increased activity of PIK3CG protein]; wortmannin inhibits the reaction [Isoproterenol results in increased activity of PIK3CG protein] CTD PMID:15178407 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression ISO Isoproterenol results in increased expression of PIK3R1 mRNA CTD PMID:20003209 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pim3 Pim-3 proto-oncogene, serine/threonine kinase increases expression ISO Isoproterenol results in increased expression of PIM3 mRNA CTD PMID:20003209 NCBI chr 7:119,953,377...119,956,587
Ensembl chr 7:119,953,175...119,956,587
JBrowse link
G Pir pirin increases expression ISO Isoproterenol results in increased expression of PIR mRNA CTD PMID:20003209 NCBI chr  X:30,108,536...30,219,269
Ensembl chr  X:30,108,538...30,219,218
JBrowse link
G Pirb paired Ig-like receptor B increases expression ISO Isoproterenol results in increased expression of LILRB3 mRNA CTD PMID:20003209 NCBI chr 1:65,499,195...65,506,666
Ensembl chr 1:65,499,195...65,506,666
JBrowse link
G Pitpnc1 phosphatidylinositol transfer protein, cytoplasmic 1 decreases expression ISO Isoproterenol results in decreased expression of PITPNC1 mRNA CTD PMID:20003209 NCBI chr10:92,163,558...92,428,971
Ensembl chr10:92,167,196...92,429,297
JBrowse link
G Pla2g4a phospholipase A2 group 4A increases expression EXP Isoproterenol results in increased expression of PLA2G4A mRNA CTD PMID:20211217 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Pla2g7 phospholipase A2 group VII multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of PLA2G7 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476
JBrowse link
G Plagl1 PLAG1 like zinc finger 1 increases expression ISO Isoproterenol results in increased expression of PLAGL1 mRNA CTD PMID:20003209 NCBI chr 1:7,477,295...7,517,229
Ensembl chr 1:7,477,177...7,517,228
JBrowse link
G Plat plasminogen activator, tissue type multiple interactions
increases expression
increases secretion
EXP Cycloheximide promotes the reaction [Isoproterenol results in increased expression of PLAT mRNA]
Isoproterenol results in increased secretion of PLAT protein
CTD PMID:2477232 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Plau plasminogen activator, urokinase increases expression EXP Isoproterenol results in increased expression of PLAU mRNA CTD PMID:20211217 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Plcb4 phospholipase C, beta 4 increases expression ISO Isoproterenol results in increased expression of PLCB4 mRNA CTD PMID:20003209 NCBI chr 3:122,952,965...123,322,522
Ensembl chr 3:122,953,196...123,322,392
JBrowse link
G Pld1 phospholipase D1 increases expression ISO Isoproterenol results in increased expression of PLD1 mRNA CTD PMID:20003209 NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692
JBrowse link
G Pln phospholamban multiple interactions
increases phosphorylation
decreases phosphorylation
EXP astragaloside A inhibits the reaction [Isoproterenol results in decreased phosphorylation of PLN protein]; candesartan inhibits the reaction [Isoproterenol results in decreased phosphorylation of PLN protein]; Isoproterenol results in decreased expression of and results in decreased phosphorylation of PLN protein; Propranolol inhibits the reaction [Isoproterenol results in decreased expression of and results in decreased phosphorylation of PLN protein]
Isoproterenol results in increased phosphorylation of PLN protein
CTD PMID:10997724 PMID:16723803 PMID:17509559 PMID:21268078 NCBI chr20:32,629,537...32,639,559 JBrowse link
G Plxnd1 plexin D1 decreases expression ISO Isoproterenol results in decreased expression of PLXND1 mRNA CTD PMID:20003209 NCBI chr 4:149,002,786...149,043,097
Ensembl chr 4:149,002,784...149,043,244
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Isoproterenol results in increased expression of PMAIP1 mRNA CTD PMID:24286936 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Pnlip pancreatic lipase multiple interactions
increases activity
EXP oleuropein inhibits the reaction [Isoproterenol results in increased activity of PNLIP protein] CTD PMID:26056852 NCBI chr 1:257,774,012...257,811,656
Ensembl chr 1:257,798,581...257,811,654
JBrowse link
G Pnp purine nucleoside phosphorylase increases expression ISO Isoproterenol results in increased expression of PNP mRNA CTD PMID:20003209 PMID:21335049 NCBI chr15:24,170,607...24,178,269
Ensembl chr15:24,170,602...24,203,986
JBrowse link
G Pnpla7 patatin-like phospholipase domain containing 7 increases expression ISO Isoproterenol results in increased expression of PNPLA7 mRNA CTD PMID:20003209 NCBI chr 3:7,782,572...7,861,504
Ensembl chr 3:7,782,572...7,861,497
JBrowse link
G Pomc proopiomelanocortin increases secretion EXP Isoproterenol results in increased secretion of POMC protein alternative form CTD PMID:10898105 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Popdc3 popeye domain containing 3 increases expression ISO Isoproterenol results in increased expression of POPDC3 mRNA CTD PMID:20003209 NCBI chr20:48,772,397...48,800,677
Ensembl chr20:48,772,462...48,800,593
JBrowse link
G Postn periostin increases expression
multiple interactions
ISO
EXP
Isoproterenol results in increased expression of POSTN mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADL mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADM mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADS mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADVL mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ACSL1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of AKT1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP5F1A mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP5F1D mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP5MC1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP5PO mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP6AP2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of AZI2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of BAG4 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of BIRC2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of CASP7 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of CDC37 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of CHUK mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of COPS3 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of CPT1A mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of CPT2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of CUL1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of DMAC2L mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ELP1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of GCLM mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of GLG1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of GPX1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of HADHA mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of JUN mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of KCNQ1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of KEAP1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of KPNA3 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of KPNA6 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of LRPPRC mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of MAP2K4 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of MAP3K2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NCSTN mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFA10L1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFA11 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFB2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFB5 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFB8 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFS1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFS3 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFS4 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFS8 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFV1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFV2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NFE2L2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NFKB1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NFKBIA mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NKIRAS2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NOTCH1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NQO1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NSMAF mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PEBP1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PECR mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PRKACA mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMA7 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMB1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMB5 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMB8 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMC5 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMC6 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD11 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD13 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD5 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of SLC25A20 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of SOD2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of STAT1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of STAT3 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of TBK1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of TXNRD2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of UBA1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of USP2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of XDH mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of YWHAG mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ZFAND5 mRNA; [Isoproterenol co-treated with POSTN protein] results in increased expression of ATP5ME mRNA; [Isoproterenol co-treated with POSTN protein] results in increased expression of ATP5PD mRNA; [Isoproterenol co-treated with POSTN protein] results in increased expression of BCL2 mRNA; [Isoproterenol co-treated with POSTN protein] results in increased expression of DAP mRNA; [Isoproterenol co-treated with POSTN protein] results in increased expression of TNF mRNA
CTD PMID:20003209 PMID:30303030 NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression
multiple interactions
ISO
EXP
Isoproterenol results in decreased expression of PPARA mRNA
osthol inhibits the reaction [Isoproterenol results in decreased expression of PPARA mRNA]; PPARA protein promotes the reaction [celastrol methyl ester inhibits the reaction [Isoproterenol results in decreased expression of MYH6 mRNA]]; PPARA protein promotes the reaction [celastrol methyl ester inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]]; PPARA protein promotes the reaction [celastrol methyl ester inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]]
Isoproterenol results in decreased expression of PPARA mRNA; Isoproterenol results in decreased expression of PPARA protein
Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARA mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARA protein]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARA mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARA protein]]
CTD PMID:21854795 PMID:24286936 PMID:25045214 PMID:37269933 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression
multiple interactions
ISO
EXP
Isoproterenol results in decreased expression of PPARG mRNA
osthol inhibits the reaction [Isoproterenol results in decreased expression of PPARG mRNA]
Isoproterenol results in decreased expression of PPARG mRNA; Isoproterenol results in decreased expression of PPARG protein
2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein]; [Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein; Enalapril inhibits the reaction [Isoproterenol results in decreased expression of PPARG protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein]; Hesperidin inhibits the reaction [Isoproterenol results in decreased expression of PPARG protein]
CTD PMID:21854795 PMID:24286936 PMID:24954035 PMID:30623541 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression
decreases expression
multiple interactions
EXP
ISO
Isoproterenol results in increased expression of PPARGC1A mRNA
Isoproterenol results in decreased expression of PPARGC1A mRNA; Isoproterenol results in decreased expression of PPARGC1A protein
Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARGC1A mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARGC1A protein]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARGC1A mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARGC1A protein]]
CTD PMID:19808358 PMID:25045214 PMID:34601065 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ppargc1b PPARG coactivator 1 beta decreases expression ISO Isoproterenol results in decreased expression of PPARGC1B mRNA CTD PMID:20003209 NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194
JBrowse link
G Ppfibp1 PPFIA binding protein 1 increases expression ISO Isoproterenol results in increased expression of PPFIBP1 mRNA CTD PMID:20003209 NCBI chr 4:179,807,579...179,951,428
Ensembl chr 4:179,808,794...179,951,428
JBrowse link
G Ppfibp2 PPFIA binding protein 2 increases expression ISO Isoproterenol results in increased expression of PPFIBP2 mRNA CTD PMID:20003209 NCBI chr 1:161,504,774...161,687,339
Ensembl chr 1:161,504,890...161,655,212
JBrowse link
G Ppif peptidylprolyl isomerase F decreases expression ISO Isoproterenol results in decreased expression of PPIF mRNA CTD PMID:20003209 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913
JBrowse link
G Ppil6 peptidylprolyl isomerase like 6 increases expression ISO Isoproterenol results in increased expression of PPIL6 mRNA CTD PMID:20003209 NCBI chr20:44,989,509...45,017,833
Ensembl chr20:44,988,943...45,018,340
JBrowse link
G Ppip5k2 diphosphoinositol pentakisphosphate kinase 2 increases expression ISO Isoproterenol results in increased expression of PPIP5K2 mRNA CTD PMID:20003209 NCBI chr 9:98,315,220...98,394,537
Ensembl chr 9:98,315,252...98,390,814
JBrowse link
G Ppm1e protein phosphatase, Mg2+/Mn2+ dependent, 1E increases expression ISO Isoproterenol results in increased expression of PPM1E mRNA CTD PMID:20003209 NCBI chr10:72,051,643...72,187,439
Ensembl chr10:72,055,208...72,187,282
JBrowse link
G Ppm1j protein phosphatase, Mg2+/Mn2+ dependent, 1J decreases expression ISO Isoproterenol results in decreased expression of PPM1J mRNA CTD PMID:20003209 NCBI chr 2:192,278,597...192,283,883
Ensembl chr 2:192,278,517...192,283,882
JBrowse link
G Ppp1r14c protein phosphatase 1, regulatory (inhibitor) subunit 14c decreases expression ISO Isoproterenol results in decreased expression of PPP1R14C mRNA CTD PMID:20003209 NCBI chr 1:39,773,403...39,886,970
Ensembl chr 1:39,773,403...39,886,956
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO Isoproterenol results in increased expression of PPP1R15A mRNA CTD PMID:20003209 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha affects response to substance ISO PPP2CA protein affects the susceptibility to Isoproterenol CTD PMID:15247211 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions
decreases expression
EXP geraniol inhibits the reaction [Isoproterenol results in decreased expression of PRDX1 mRNA]; geraniol inhibits the reaction [Isoproterenol results in decreased expression of PRDX1 protein]
Isoproterenol results in decreased expression of PRDX1 mRNA; Isoproterenol results in decreased expression of PRDX1 protein
CTD PMID:35608392 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Prg4 proteoglycan 4 increases expression ISO Isoproterenol results in increased expression of PRG4 mRNA CTD PMID:20003209 NCBI chr13:62,487,257...62,504,657
Ensembl chr13:62,487,257...62,504,119
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions
increases phosphorylation
ISO
EXP
Isoproterenol results in increased phosphorylation of and results in increased activity of PRKAA1 protein; orlistat inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of PRKAA1 protein]; triacsin C inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of PRKAA1 protein]
[PDE3B protein co-treated with AKT1 protein] inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]; INS protein inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]; OPC 3911 inhibits the reaction [INS protein inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]]; orlistat inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]
CTD PMID:18390901 PMID:19167487 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 decreases expression
multiple interactions
EXP Isoproterenol results in decreased expression of PRKAA2 mRNA
xanthone inhibits the reaction [Isoproterenol results in decreased expression of PRKAA2 mRNA]
CTD PMID:36414029 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of PRKACA mRNA CTD PMID:30303030 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta decreases expression
multiple interactions
EXP Isoproterenol results in decreased expression of PRKAR2B protein
natakalim inhibits the reaction [Isoproterenol results in decreased expression of PRKAR2B protein]
CTD PMID:27890915 NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933
JBrowse link
G Prkca protein kinase C, alpha increases expression EXP Isoproterenol results in increased expression of PRKCA mRNA; Isoproterenol results in increased expression of PRKCA protein CTD PMID:12775975 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcb protein kinase C, beta decreases expression ISO Isoproterenol results in decreased expression of PRKCB mRNA CTD PMID:21335049 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Prkcd protein kinase C, delta multiple interactions
increases expression
increases phosphorylation
EXP 2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKCD protein]
Isoproterenol results in increased expression of PRKCD mRNA; Isoproterenol results in increased expression of PRKCD protein
CTD PMID:12775975 PMID:16716347 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions
increases phosphorylation
increases expression
EXP 1-(methanesulfonamido-1-naphthyloxy)-2-(N-(4-methane sulfonamidophenethyl)-N-acetamido)ethane inhibits the reaction [Isoproterenol results in increased expression of PRKCE mRNA]; 1-(methanesulfonamido-1-naphthyloxy)-2-(N-(4-methane sulfonamidophenethyl)-N-acetamido)ethane inhibits the reaction [Isoproterenol results in increased expression of PRKCE protein]; 2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKCE protein]; CPU0213 inhibits the reaction [Isoproterenol results in increased expression of PRKCE mRNA]; CPU0213 inhibits the reaction [Isoproterenol results in increased expression of PRKCE protein modified form]; CPU0213 inhibits the reaction [Isoproterenol results in increased expression of PRKCE protein]; dofetilide inhibits the reaction [Isoproterenol results in increased expression of PRKCE mRNA]; dofetilide inhibits the reaction [Isoproterenol results in increased expression of PRKCE protein]
Isoproterenol results in increased expression of PRKCE mRNA; Isoproterenol results in increased expression of PRKCE protein; Isoproterenol results in increased expression of PRKCE protein modified form
CTD PMID:12775975 PMID:16716347 PMID:20307649 PMID:20723002 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Prl prolactin increases expression EXP Isoproterenol results in increased expression of PRL CTD PMID:1208595 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Prmt1 protein arginine methyltransferase 1 decreases expression ISO Isoproterenol results in decreased expression of PRMT1 mRNA CTD PMID:20003209 NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345
JBrowse link
G Prnd prion like protein doppel decreases expression ISO Isoproterenol results in decreased expression of PRND mRNA CTD PMID:20003209 NCBI chr 3:119,213,462...119,218,742
Ensembl chr 3:119,213,429...119,218,745
JBrowse link
G Prodh proline dehydrogenase decreases expression ISO Isoproterenol results in decreased expression of PRODH mRNA CTD PMID:21335049 NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305
JBrowse link
G Prox1 prospero homeobox 1 decreases expression ISO Isoproterenol results in decreased expression of PROX1 mRNA CTD PMID:20003209 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183
JBrowse link
G Psen1 presenilin 1 increases expression ISO Isoproterenol results in increased expression of PSEN1 mRNA CTD PMID:21335049 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Psip1 PC4 and SRSF1 interacting protein 1 increases expression ISO Isoproterenol results in increased expression of PSIP1 mRNA CTD PMID:20003209 NCBI chr 5:97,847,010...97,879,280
Ensembl chr 5:97,847,015...97,879,257
JBrowse link
G Psma7 proteasome 20S subunit alpha 7 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMA7 mRNA CTD PMID:30303030 NCBI chr 3:167,137,279...167,143,626
Ensembl chr 3:167,137,263...167,143,672
JBrowse link
G Psmb1 proteasome 20S subunit beta 1 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMB1 mRNA CTD PMID:30303030 NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560
JBrowse link
G Psmb5 proteasome 20S subunit beta 5 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMB5 mRNA CTD PMID:30303030 NCBI chr15:28,072,772...28,077,367
Ensembl chr15:28,072,781...28,077,440
JBrowse link
G Psmb8 proteasome 20S subunit beta 8 multiple interactions
decreases expression
EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMB8 mRNA
Isoproterenol results in decreased expression of PSMB8 mRNA
CTD PMID:30303030 NCBI chr20:4,652,159...4,655,122
Ensembl chr20:4,652,159...4,655,283
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMC5 mRNA CTD PMID:30303030 NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135
JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMC6 mRNA CTD PMID:30303030 NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055
JBrowse link
G Psmd1 proteasome 26S subunit, non-ATPase 1 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD1 mRNA CTD PMID:30303030 NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211
JBrowse link
G Psmd11 proteasome 26S subunit, non-ATPase 11 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD11 mRNA CTD PMID:30303030 NCBI chr10:65,433,853...65,479,774
Ensembl chr10:65,433,853...65,479,766
JBrowse link
G Psmd13 proteasome 26S subunit, non-ATPase 13 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD13 mRNA CTD PMID:30303030 NCBI chr 1:195,964,617...195,976,895
Ensembl chr 1:195,964,138...195,976,905
JBrowse link
G Psmd2 proteasome 26S subunit ubiquitin receptor, non-ATPase 2 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD2 mRNA CTD PMID:30303030 NCBI chr11:80,248,364...80,258,991
Ensembl chr11:80,248,364...80,259,043
JBrowse link
G Psmd5 proteasome 26S subunit, non-ATPase 5 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD5 mRNA CTD PMID:30303030 NCBI chr 3:18,133,715...18,151,000
Ensembl chr 3:18,133,717...18,151,029
JBrowse link
G Psmd9 proteasome 26S subunit, non-ATPase 9 increases expression EXP Isoproterenol results in increased expression of PSMD9 mRNA CTD PMID:30303030 NCBI chr12:33,337,182...33,357,468 JBrowse link
G Pten phosphatase and tensin homolog increases expression ISO
EXP
Isoproterenol results in increased expression of PTEN mRNA
Isoproterenol results in increased expression of PTEN mRNA; Isoproterenol results in increased expression of PTEN protein
CTD PMID:16188065 PMID:20003209 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptgds prostaglandin D2 synthase increases expression ISO Isoproterenol results in increased expression of PTGDS mRNA CTD PMID:20003209 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 increases expression ISO Isoproterenol results in increased expression of PTGS1 mRNA CTD PMID:20003209 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
decreases expression
EXP
ISO
Apigenin inhibits the reaction [Isoproterenol results in increased expression of PTGS2 protein]; BAY 58-2667 inhibits the reaction [Isoproterenol results in increased expression of PTGS2 mRNA]; Doxorubicin inhibits the reaction [Isoproterenol results in increased expression of PTGS2 protein]; mangostin inhibits the reaction [Isoproterenol results in increased expression of PTGS2 protein]
Isoproterenol results in increased expression of PTGS2 mRNA; Isoproterenol results in increased expression of PTGS2 protein
Isoproterenol results in decreased expression of PTGS2 mRNA
CTD PMID:18424012 PMID:19466570 PMID:19667237 PMID:22908232 PMID:30152906 More... NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pth1r parathyroid hormone 1 receptor increases expression ISO Isoproterenol results in increased expression of PTH1R mRNA CTD PMID:20003209 NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 increases expression ISO Isoproterenol results in increased expression of PTP4A1 mRNA CTD PMID:20003209 NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 increases expression ISO Isoproterenol results in increased expression of PTPN11 mRNA CTD PMID:20003209 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
JBrowse link
G Ptpn12 protein tyrosine phosphatase, non-receptor type 12 increases expression ISO Isoproterenol results in increased expression of PTPN12 mRNA CTD PMID:20003209 NCBI chr 4:14,020,997...14,092,931
Ensembl chr 4:14,021,052...14,092,927
JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 multiple interactions
increases expression
EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Isoproterenol results in increased expression of PTPN5 protein]; Anisomycin inhibits the reaction [Isoproterenol results in increased expression of PTPN5 protein]; Atenolol inhibits the reaction [Isoproterenol results in increased expression of PTPN5 protein]; Cycloheximide inhibits the reaction [Isoproterenol results in increased expression of PTPN5 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of PTPN5 protein]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of PTPN5 protein]; SL 327 inhibits the reaction [Isoproterenol results in increased expression of PTPN5 protein] CTD PMID:17623046 NCBI chr 1:97,620,638...97,681,186
Ensembl chr 1:97,620,642...97,679,882
JBrowse link
G Ptprd protein tyrosine phosphatase, receptor type, D decreases expression ISO Isoproterenol results in decreased expression of PTPRD mRNA CTD PMID:21335049 NCBI chr 5:90,046,993...90,698,977
NCBI chr 5:91,122,354...91,641,754
Ensembl chr 5:90,048,966...92,369,396
JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F increases expression ISO Isoproterenol results in increased expression of PTPRF mRNA CTD PMID:20003209 NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
JBrowse link
G Ptx3 pentraxin 3 increases expression ISO Isoproterenol results in increased expression of PTX3 mRNA CTD PMID:20003209 PMID:21823215 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
JBrowse link
G Pvr PVR cell adhesion molecule increases expression EXP Isoproterenol results in increased expression of PVR mRNA CTD PMID:20211217 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715
JBrowse link
G Pygl glycogen phosphorylase L increases activity EXP Isoproterenol results in increased activity of PYGL protein CTD PMID:6430282 NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
JBrowse link
G Qdpr quinoid dihydropteridine reductase decreases expression ISO Isoproterenol results in decreased expression of QDPR mRNA CTD PMID:21335049 NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854
JBrowse link
G R3hdm1 R3H domain containing 1 increases expression ISO Isoproterenol results in increased expression of R3HDM1 mRNA CTD PMID:20003209 NCBI chr13:39,595,848...39,733,876
Ensembl chr13:39,595,848...39,733,876
JBrowse link
G Rab1a RAB1A, member RAS oncogene family increases expression ISO Isoproterenol results in increased expression of RAB1A mRNA CTD PMID:21335049 NCBI chr14:94,422,219...94,448,799
Ensembl chr14:94,415,275...94,448,248
JBrowse link
G Rab27a RAB27A, member RAS oncogene family increases expression ISO Isoproterenol results in increased expression of RAB27A mRNA CTD PMID:20003209 NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829
JBrowse link
G Rab33b RAB33B, member RAS oncogene family increases expression ISO Isoproterenol results in increased expression of RAB33B mRNA CTD PMID:21335049 NCBI chr 2:135,528,116...135,538,719
Ensembl chr 2:135,528,116...135,538,719
JBrowse link
G Rab4a RAB4A, member RAS oncogene family increases expression ISO Isoproterenol results in increased expression of RAB4A mRNA CTD PMID:20003209 NCBI chr19:51,795,613...51,822,706
Ensembl chr19:51,795,613...51,822,703
JBrowse link
G Rad52 RAD52 homolog, DNA repair protein increases expression ISO Isoproterenol results in increased expression of RAD52 mRNA CTD PMID:20003209 NCBI chr 4:153,106,062...153,128,598
Ensembl chr 4:153,106,062...153,128,207
JBrowse link
G Ramp1 receptor activity modifying protein 1 decreases expression
increases expression
ISO
EXP
Isoproterenol results in decreased expression of RAMP1 mRNA
Isoproterenol results in increased expression of RAMP1 mRNA; Isoproterenol results in increased expression of RAMP1 protein
CTD PMID:16987513 PMID:17250927 PMID:17306419 PMID:20003209 NCBI chr 9:91,765,481...91,816,152
Ensembl chr 9:91,781,285...91,816,151
JBrowse link
G Ramp2 receptor activity modifying protein 2 multiple interactions
increases expression
EXP [Phenylephrine co-treated with Isoproterenol] results in increased expression of RAMP2 mRNA
Isoproterenol results in increased expression of RAMP2 mRNA; Isoproterenol results in increased expression of RAMP2 protein
CTD PMID:12732346 PMID:16987513 PMID:17250927 PMID:17306419 NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829
JBrowse link
G Ramp3 receptor activity modifying protein 3 increases expression EXP Isoproterenol results in increased expression of RAMP3 mRNA; Isoproterenol results in increased expression of RAMP3 protein CTD PMID:16987513 PMID:17306419 NCBI chr14:81,527,404...81,544,905
Ensembl chr14:81,527,385...81,544,902
JBrowse link
G Ranbp9 RAN binding protein 9 increases expression ISO Isoproterenol results in increased expression of RANBP9 mRNA CTD PMID:20003209 NCBI chr17:21,220,807...21,303,009
Ensembl chr17:21,220,618...21,303,004
JBrowse link
G Rangap1 RAN GTPase activating protein 1 increases expression ISO Isoproterenol results in increased expression of RANGAP1 mRNA CTD PMID:21335049 NCBI chr 7:113,224,695...113,250,441
Ensembl chr 7:113,224,703...113,250,438
JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 increases expression
multiple interactions
increases response to substance
ISO Isoproterenol results in increased expression of RAPGEF3 mRNA
RAPGEF3 mutant form inhibits the reaction [Isoproterenol inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]]
RAPGEF3 results in increased susceptibility to Isoproterenol
CTD PMID:17557924 PMID:21745194 NCBI chr 7:128,875,772...128,898,203
Ensembl chr 7:128,875,773...128,898,521
JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 increases expression ISO Isoproterenol results in increased expression of RAPGEF4 mRNA CTD PMID:17557924 NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316
JBrowse link
G Raph1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 increases expression ISO Isoproterenol results in increased expression of RAPH1 mRNA CTD PMID:20003209 NCBI chr 9:61,907,476...61,990,170
Ensembl chr 9:61,907,758...61,961,209
JBrowse link
G Rasa1 RAS p21 protein activator 1 affects localization
multiple interactions
EXP Isoproterenol affects the localization of RASA1 protein
Isoproterenol results in increased expression of and results in increased phosphorylation of RASA1 protein
CTD PMID:1382416 NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854
JBrowse link
G Rasd1 ras related dexamethasone induced 1 increases expression ISO Isoproterenol results in increased expression of RASD1 mRNA CTD PMID:20003209 NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186
JBrowse link
G Rasgef1b RasGEF domain family, member 1B increases expression ISO Isoproterenol results in increased expression of RASGEF1B mRNA CTD PMID:20003209 NCBI chr14:9,859,512...10,380,044
Ensembl chr14:9,860,247...10,379,741
JBrowse link
G Rasl10a RAS-like, family 10, member A increases expression ISO Isoproterenol results in increased expression of RASL10A mRNA CTD PMID:20003209 NCBI chr14:79,955,093...79,956,471
Ensembl chr14:79,954,398...79,956,468
JBrowse link
G Rassf1 Ras association domain family member 1 decreases expression EXP Isoproterenol results in decreased expression of RASSF1 mRNA; Isoproterenol results in decreased expression of RASSF1 protein CTD PMID:24945829 NCBI chr 8:108,225,023...108,236,164
Ensembl chr 8:108,225,023...108,236,164
JBrowse link
G Rassf4 Ras association domain family member 4 increases expression ISO Isoproterenol results in increased expression of RASSF4 mRNA CTD PMID:20003209 NCBI chr 4:149,897,525...149,932,658
Ensembl chr 4:149,897,543...149,932,411
JBrowse link
G Rbbp4 RB binding protein 4, chromatin remodeling factor decreases expression ISO Isoproterenol results in decreased expression of RBBP4 mRNA CTD PMID:20003209 NCBI chr 5:141,655,863...141,675,157
Ensembl chr 5:141,638,421...141,675,284
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 increases expression ISO Isoproterenol results in increased expression of RBL2 mRNA CTD PMID:20003209 NCBI chr19:15,876,852...15,923,632
Ensembl chr19:15,876,853...15,923,572
JBrowse link
G Rbm33 RNA binding motif protein 33 increases expression ISO Isoproterenol results in increased expression of RBM33 mRNA CTD PMID:20003209 NCBI chr 4:6,980,807...7,088,334
Ensembl chr 4:6,983,970...7,089,918
JBrowse link
G Rbmx RNA binding motif protein, X-linked decreases expression ISO Isoproterenol results in decreased expression of RBMX mRNA CTD PMID:20003209 NCBI chr  X:135,305,237...135,314,806
Ensembl chr  X:135,305,325...135,314,743
JBrowse link
G Rbp7 retinol binding protein 7 increases expression ISO Isoproterenol results in increased expression of RBP7 mRNA CTD PMID:20003209 NCBI chr 5:159,889,723...159,894,338
Ensembl chr 5:159,889,723...159,894,339
JBrowse link
G Reep1 receptor accessory protein 1 decreases expression ISO Isoproterenol results in decreased expression of REEP1 mRNA CTD PMID:20003209 NCBI chr 4:103,746,004...103,862,347
Ensembl chr 4:103,745,633...103,862,338
JBrowse link
G Reg3b regenerating family member 3 beta decreases expression
increases expression
EXP Isoproterenol results in decreased expression of REG3B mRNA
Isoproterenol results in increased expression of REG3B mRNA
CTD PMID:20211217 PMID:24286936 NCBI chr 4:110,861,775...110,865,015
Ensembl chr 4:110,861,775...110,865,015
JBrowse link
G Reg3g regenerating family member 3 gamma decreases expression ISO Isoproterenol results in decreased expression of REG3G mRNA CTD PMID:24286936 NCBI chr 4:110,922,805...110,927,803
Ensembl chr 4:110,924,168...110,926,723
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases activity
increases localization
increases expression
affects localization
ISO
EXP
Isoproterenol results in increased activity of [NFKB1 protein binds to RELA protein]; osthol inhibits the reaction [Isoproterenol results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased activity of [NFKB1 protein binds to RELA protein]]
anethole inhibits the reaction [Isoproterenol results in increased expression of RELA protein]; Enalapril inhibits the reaction [Isoproterenol results in increased expression of RELA protein]; Hesperidin inhibits the reaction [Isoproterenol results in increased expression of RELA protein]; Isoproterenol affects the reaction [Lipopolysaccharides affects the localization of RELA protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased expression of RELA protein]; punicalagin inhibits the reaction [Isoproterenol results in increased expression of RELA protein]; RELA mRNA promotes the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; RELA mRNA promotes the reaction [Isoproterenol results in increased expression of NPPA mRNA]; RELA mRNA promotes the reaction [Isoproterenol results in increased expression of NPPB mRNA]; Sirolimus inhibits the reaction [Isoproterenol affects the localization of RELA protein]
Isoproterenol results in increased activity of RELA protein
Isoproterenol results in increased localization of RELA protein
Isoproterenol results in increased expression of RELA mRNA; Isoproterenol results in increased expression of RELA protein
CTD PMID:15178407 PMID:15710352 PMID:18487443 PMID:21854795 PMID:25045214 More... NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Ren renin increases activity
increases expression
increases secretion
multiple interactions
ISO
EXP
Isoproterenol results in increased activity of REN protein
Isoproterenol results in increased expression of REN protein
Isoproterenol results in increased expression of REN mRNA
Isoproterenol results in increased secretion of REN protein
Propranolol inhibits the reaction [Isoproterenol results in increased expression of REN protein]
[aliskiren co-treated with Carvedilol] inhibits the reaction [Isoproterenol results in increased activity of REN protein]; aliskiren inhibits the reaction [Isoproterenol results in increased activity of REN protein]; Carvedilol inhibits the reaction [Isoproterenol results in increased activity of REN protein]; Losartan promotes the reaction [Isoproterenol results in increased expression of REN protein]; Quinapril promotes the reaction [Isoproterenol results in increased expression of REN protein]; Ramipril inhibits the reaction [Isoproterenol results in increased expression of REN protein]
[Sodium, Dietary deficiency results in increased susceptibility to Isoproterenol] which results in increased secretion of REN protein; Isoproterenol promotes the reaction [CD38 gene mutant form results in increased activity of REN protein]
CTD PMID:1653766 PMID:3515047 PMID:3910304 PMID:6314140 PMID:9539862 More... NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Rfc5 replication factor C subunit 5 decreases expression ISO Isoproterenol results in decreased expression of RFC5 mRNA CTD PMID:21335049 NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312
JBrowse link
G Rhoj ras homolog family member J increases expression ISO Isoproterenol results in increased expression of RHOJ mRNA CTD PMID:20003209 NCBI chr 6:94,035,307...94,117,642
Ensembl chr 6:94,035,483...94,118,275
JBrowse link
G Rhou ras homolog family member U increases expression ISO Isoproterenol results in increased expression of RHOU mRNA CTD PMID:20003209 NCBI chr19:51,641,476...51,651,249
Ensembl chr19:51,641,227...51,650,552
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 multiple interactions
increases expression
EXP thymoquinone inhibits the reaction [Isoproterenol results in increased expression of RIPK1 protein] CTD PMID:35940283 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 multiple interactions
increases expression
EXP thymoquinone inhibits the reaction [Isoproterenol results in increased expression of RIPK3 protein] CTD PMID:35940283 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
JBrowse link
G Rln3 relaxin 3 increases expression EXP Isoproterenol results in increased expression of RLN3 mRNA; Isoproterenol results in increased expression of RLN3 protein CTD PMID:16112403 NCBI chr19:24,107,401...24,109,432
Ensembl chr19:24,107,401...24,109,886
JBrowse link
G Rnase4 ribonuclease A family member 4 increases expression ISO Isoproterenol results in increased expression of RNASE4 mRNA CTD PMID:20003209 NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117
JBrowse link
G Rnd1 Rho family GTPase 1 increases expression EXP Isoproterenol results in increased expression of RND1 mRNA CTD PMID:20211217 PMID:23558518 NCBI chr 7:129,821,311...129,828,385
Ensembl chr 7:129,821,311...129,828,399
JBrowse link
G Rnf103 ring finger protein 103 increases expression ISO Isoproterenol results in increased expression of RNF103 mRNA CTD PMID:20003209 NCBI chr 4:103,526,456...103,542,529
Ensembl chr 4:103,526,502...103,555,919
JBrowse link
G Rnf128 ring finger protein 128 increases expression ISO Isoproterenol results in increased expression of RNF128 mRNA CTD PMID:20003209 NCBI chr  X:103,183,643...103,298,431
Ensembl chr  X:103,183,831...103,298,423
JBrowse link
G Rnf144b ring finger protein 144B increases expression ISO Isoproterenol results in increased expression of RNF144B mRNA CTD PMID:20003209 NCBI chr17:17,431,271...17,580,687
Ensembl chr17:17,432,786...17,562,760
JBrowse link
G Rnf207 ring finger protein 207 decreases expression ISO Isoproterenol results in decreased expression of RNF207 mRNA CTD PMID:20003209 NCBI chr 5:162,815,351...162,828,325
Ensembl chr 5:162,815,357...162,828,375
JBrowse link
G Ro60 Ro60, Y RNA binding protein increases expression ISO Isoproterenol results in increased expression of RO60 mRNA CTD PMID:20003209 NCBI chr13:55,499,514...55,520,504
Ensembl chr13:55,499,534...55,520,504
JBrowse link
G Rpl27a ribosomal protein L27A decreases expression ISO Isoproterenol results in decreased expression of RPL27A mRNA CTD PMID:20003209 NCBI chr 1:163,539,732...163,542,771 JBrowse link
G Rpl37a ribosomal protein L37A decreases expression ISO Isoproterenol results in decreased expression of RPL37A mRNA CTD PMID:21335049 NCBI chr 9:74,298,843...74,300,926 JBrowse link
G Rpn1 ribophorin I increases expression ISO Isoproterenol results in increased expression of RPN1 mRNA CTD PMID:21823215 NCBI chr 4:120,543,667...120,565,069
Ensembl chr 4:120,543,667...120,565,069
JBrowse link
G Rps26 ribosomal protein S26 decreases expression ISO Isoproterenol results in decreased expression of RPS26 mRNA CTD PMID:21335049 NCBI chr 7:1,057,332...1,058,882 JBrowse link
G Rps27a ribosomal protein S27a decreases expression ISO Isoproterenol results in decreased expression of RPS27A mRNA CTD PMID:21335049 NCBI chr14:103,285,734...103,288,011
Ensembl chr14:103,285,734...103,288,011
Ensembl chr 5:103,285,734...103,288,011
JBrowse link
G Rps3a ribosomal protein S3a decreases expression ISO Isoproterenol results in decreased expression of RPS3A mRNA CTD PMID:21335049 NCBI chr 2:171,524,685...171,529,054
Ensembl chr 2:171,524,500...171,529,055
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 increases phosphorylation
affects expression
ISO
EXP
Isoproterenol results in increased phosphorylation of RPS6KB1 protein
Isoproterenol affects the expression of RPS6KB1 mRNA
CTD PMID:18812163 PMID:28099878 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator decreases expression ISO Isoproterenol results in decreased expression of RRAD mRNA CTD PMID:20003209 NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417
JBrowse link
G Rsf1 remodeling and spacing factor 1 increases expression ISO Isoproterenol results in increased expression of RSF1 mRNA CTD PMID:20003209 NCBI chr 1:151,892,055...152,015,089
Ensembl chr 1:151,892,434...152,009,051
JBrowse link
G RT1-Ba RT1 class II, locus Ba decreases expression ISO Isoproterenol results in decreased expression of H2-AA mRNA CTD PMID:20003209 NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744
JBrowse link
G RT1-Bb RT1 class II, locus Bb decreases expression ISO Isoproterenol results in decreased expression of H2-AB1 mRNA CTD PMID:20003209 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 decreases expression ISO Isoproterenol results in decreased expression of H2-EB1 mRNA CTD PMID:20003209 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G RT1-DMa RT1 class II, locus DMa decreases expression ISO Isoproterenol results in decreased expression of H2-DMA mRNA CTD PMID:20003209 NCBI chr20:4,707,028...4,710,432
Ensembl chr20:4,707,028...4,710,432
JBrowse link
G Ryr2 ryanodine receptor 2 multiple interactions
increases phosphorylation
EXP
ISO
candesartan inhibits the reaction [Isoproterenol results in increased phosphorylation of RYR2 protein]
carvedilol inhibits the reaction [Isoproterenol results in increased phosphorylation of RYR2 protein]
CTD PMID:16723803 PMID:21743453 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142
JBrowse link
G S100a11 S100 calcium binding protein A11 increases expression EXP Isoproterenol results in increased expression of S100A11 protein CTD PMID:10886724 NCBI chr 2:179,191,688...179,197,098
Ensembl chr 2:179,191,715...179,197,044
JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression EXP Isoproterenol results in increased expression of S100A4 protein CTD PMID:10886724 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
JBrowse link
G S100a8 S100 calcium binding protein A8 multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of S100A8 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
JBrowse link
G S100a9 S100 calcium binding protein A9 multiple interactions
increases expression
ISO
EXP
Doxycycline inhibits the reaction [Isoproterenol results in increased expression of S100A9 mRNA]
Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of S100A9 protein]; pifithrin inhibits the reaction [Isoproterenol results in increased expression of S100A9 protein]; S100A9 protein affects the reaction [Isoproterenol results in increased expression of and results in increased phosphorylation of TP53 protein]; S100A9 protein affects the reaction [Isoproterenol results in increased expression of C3 protein]; S100A9 protein affects the reaction [Isoproterenol results in increased expression of C5 protein]; S100A9 protein affects the reaction [Isoproterenol results in increased expression of CASP3 protein]
CTD PMID:18089841 PMID:20003209 PMID:32924446 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of S1PR1 mRNA]; Doxycycline inhibits the reaction [Isoproterenol results in increased expression of S1PR1 protein]
Isoproterenol results in increased expression of S1PR1 mRNA; Isoproterenol results in increased expression of S1PR1 protein
CTD PMID:18089841 PMID:20003209 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
JBrowse link
G Saa4 serum amyloid A4 increases expression ISO Isoproterenol results in increased expression of SAA4 mRNA CTD PMID:21335049 NCBI chr 1:97,247,580...97,251,882 JBrowse link
G Sbno2 strawberry notch homolog 2 increases expression ISO Isoproterenol results in increased expression of SBNO2 mRNA CTD PMID:20003209 NCBI chr 7:9,605,572...9,649,529
Ensembl chr 7:9,605,627...9,649,527
JBrowse link
G Scara5 scavenger receptor class A, member 5 increases expression ISO Isoproterenol results in increased expression of SCARA5 mRNA CTD PMID:20003209 NCBI chr15:39,880,017...39,985,007
Ensembl chr15:39,880,035...39,983,373
JBrowse link
G Scarb2 scavenger receptor class B, member 2 increases expression ISO Isoproterenol results in increased expression of SCARB2 mRNA CTD PMID:20003209 NCBI chr14:15,558,271...15,609,813
Ensembl chr14:15,558,236...15,609,813
JBrowse link
G Scgb3a1 secretoglobin, family 3A, member 1 increases expression ISO Isoproterenol results in increased expression of SCGB3A1 mRNA CTD PMID:20003209 NCBI chr10:33,968,059...33,969,366
Ensembl chr10:33,968,059...33,969,476
JBrowse link
G Scn3a sodium voltage-gated channel alpha subunit 3 increases expression ISO Isoproterenol results in increased expression of SCN3A mRNA CTD PMID:20003209 NCBI chr 3:50,146,411...50,258,119
Ensembl chr 3:50,148,139...50,258,119
JBrowse link
G Scn4b sodium voltage-gated channel beta subunit 4 decreases expression ISO Isoproterenol results in decreased expression of SCN4B mRNA CTD PMID:20003209 NCBI chr 8:45,446,580...45,462,294
Ensembl chr 8:45,446,215...45,462,292
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 increases expression EXP Isoproterenol results in increased expression of SCN5A mRNA CTD PMID:17526999 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
JBrowse link
G Scn7a sodium voltage-gated channel alpha subunit 7 increases expression ISO Isoproterenol results in increased expression of SCN7A mRNA CTD PMID:20003209 NCBI chr 3:51,335,841...51,438,308
Ensembl chr 3:51,335,841...51,438,256
JBrowse link
G Scpep1 serine carboxypeptidase 1 increases expression ISO Isoproterenol results in increased expression of SCPEP1 mRNA CTD PMID:20003209 NCBI chr10:73,703,275...73,732,892
Ensembl chr10:73,703,278...73,732,850
JBrowse link
G Scube2 signal peptide, CUB domain and EGF like domain containing 2 decreases expression ISO Isoproterenol results in decreased expression of SCUBE2 mRNA CTD PMID:20003209 NCBI chr 1:163,831,876...163,899,925
Ensembl chr 1:163,832,015...163,899,393
JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 increases expression ISO Isoproterenol results in increased expression of SDF2L1 mRNA CTD PMID:21823215 NCBI chr11:83,872,659...83,874,902
Ensembl chr11:83,872,659...83,874,902
JBrowse link
G Sele selectin E multiple interactions ISO Isoproterenol inhibits the reaction [TNF protein results in increased secretion of SELE mRNA] CTD PMID:8780174 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Selenop selenoprotein P increases expression ISO Isoproterenol results in increased expression of SELENOP mRNA CTD PMID:21335049 NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852
JBrowse link
G Sell selectin L multiple interactions ISO Isoproterenol promotes the reaction [Theophylline inhibits the reaction [Platelet Activating Factor results in increased secretion of SELL protein]] CTD PMID:9762784 NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456
JBrowse link
G Sema3g semaphorin 3G increases expression ISO Isoproterenol results in increased expression of SEMA3G mRNA CTD PMID:20003209 NCBI chr16:6,413,589...6,425,221
Ensembl chr16:6,413,589...6,425,221
JBrowse link
G Sema5a semaphorin 5A increases expression ISO Isoproterenol results in increased expression of SEMA5A mRNA CTD PMID:20003209 NCBI chr 2:83,309,843...83,741,084
Ensembl chr 2:83,309,843...83,741,084
JBrowse link
G Serinc3 serine incorporator 3 increases expression ISO Isoproterenol results in increased expression of SERINC3 mRNA CTD PMID:20003209 NCBI chr 3:152,301,882...152,321,327
Ensembl chr 3:152,301,772...152,321,808
JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of SERPINA3N mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433
JBrowse link
G Serpina7 serpin family A member 7 increases expression ISO Isoproterenol results in increased expression of SERPINA7 mRNA CTD PMID:21335049 NCBI chr  X:102,663,242...102,722,319
Ensembl chr  X:102,663,405...102,669,040
JBrowse link
G Serpine1 serpin family E member 1 increases expression
decreases expression
EXP Isoproterenol results in increased expression of SERPINE1 mRNA
Isoproterenol results in decreased expression of SERPINE1 protein
CTD PMID:20211217 PMID:23558518 PMID:24286936 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serping1 serpin family G member 1 increases expression ISO Isoproterenol results in increased expression of SERPING1 mRNA CTD PMID:20003209 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034
JBrowse link
G Sesn1 sestrin 1 increases expression ISO Isoproterenol results in increased expression of SESN1 mRNA CTD PMID:20003209 NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697
JBrowse link
G Set Set nuclear proto-oncogene decreases expression ISO Isoproterenol results in decreased expression of SET mRNA CTD PMID:20003209 NCBI chr 3:13,334,564...13,345,598
Ensembl chr 3:13,335,041...13,363,567
JBrowse link
G Setdb2 SET domain bifurcated histone lysine methyltransferase 2 increases expression ISO Isoproterenol results in increased expression of SETDB2 mRNA CTD PMID:20003209 NCBI chr15:33,553,657...33,606,586
Ensembl chr15:33,453,952...33,606,470
JBrowse link
G Sfn stratifin decreases expression ISO Isoproterenol results in decreased expression of SFN mRNA CTD PMID:24286936 NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314
JBrowse link
G Sgcg sarcoglycan, gamma decreases expression EXP Isoproterenol results in decreased expression of SGCG CTD PMID:18808529 NCBI chr15:35,388,836...35,435,072
Ensembl chr15:35,386,534...35,435,148
JBrowse link
G Sgms1 sphingomyelin synthase 1 increases expression ISO Isoproterenol results in increased expression of SGMS1 mRNA CTD PMID:20003209 NCBI chr 1:229,996,673...230,259,591
Ensembl chr 1:229,998,119...230,259,603
JBrowse link
G Sh3d19 SH3 domain containing 19 increases expression ISO Isoproterenol results in increased expression of SH3D19 mRNA CTD PMID:20003209 NCBI chr 2:171,356,244...171,516,042
Ensembl chr 2:171,356,251...171,515,561
JBrowse link
G Sh3kbp1 SH3 domain-containing kinase-binding protein 1 decreases expression ISO Isoproterenol results in decreased expression of SH3KBP1 mRNA CTD PMID:20003209 NCBI chr  X:34,877,862...35,223,013
Ensembl chr  X:34,877,866...35,222,747
JBrowse link
G Shroom2 shroom family member 2 increases expression ISO Isoproterenol results in increased expression of SHROOM2 mRNA CTD PMID:20003209 NCBI chr  X:21,812,469...21,983,724
Ensembl chr  X:21,812,469...21,984,153
JBrowse link
G Sik1 salt-inducible kinase 1 increases expression ISO Isoproterenol results in increased expression of SIK1 mRNA CTD PMID:34601065 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
JBrowse link
G Sirt6 sirtuin 6 decreases expression
multiple interactions
EXP Isoproterenol results in decreased expression of SIRT6 mRNA
xanthone inhibits the reaction [Isoproterenol results in decreased expression of SIRT6 mRNA]
CTD PMID:36414029 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914
JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor decreases expression ISO Isoproterenol results in decreased expression of SIVA1 mRNA CTD PMID:20003209 NCBI chr 6:131,705,323...131,709,697
Ensembl chr 6:131,705,323...131,709,690
JBrowse link
G Six4 SIX homeobox 4 increases expression ISO Isoproterenol results in increased expression of SIX4 mRNA CTD PMID:20003209 NCBI chr 6:91,802,328...91,816,002
Ensembl chr 6:91,802,329...91,815,992
JBrowse link
G Slc10a6 solute carrier family 10 member 6 increases expression ISO Isoproterenol results in increased expression of SLC10A6 mRNA CTD PMID:20003209 NCBI chr14:6,080,716...6,102,902
Ensembl chr14:6,080,717...6,103,037
JBrowse link
G Slc25a10 solute carrier family 25 member 10 decreases expression ISO Isoproterenol results in decreased expression of SLC25A10 mRNA CTD PMID:20003209 NCBI chr10:105,765,598...105,775,159
Ensembl chr10:105,765,372...105,773,556
JBrowse link
G Slc25a20 solute carrier family 25 member 20 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of SLC25A20 mRNA CTD PMID:30303030 NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
JBrowse link
G Slc25a30 solute carrier family 25, member 30 increases expression ISO Isoproterenol results in increased expression of SLC25A30 mRNA CTD PMID:20003209 NCBI chr15:51,076,998...51,099,613
Ensembl chr15:51,077,002...51,099,613
JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression ISO Isoproterenol results in increased expression of SLC2A1 mRNA CTD PMID:20003209 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slc2a4 solute carrier family 2 member 4 decreases expression EXP Isoproterenol results in decreased expression of SLC2A4 protein CTD PMID:19826179 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc36a2 solute carrier family 36 member 2 decreases expression ISO Isoproterenol results in decreased expression of SLC36A2 mRNA CTD PMID:20003209 NCBI chr10:39,278,002...39,306,082
Ensembl chr10:39,278,046...39,306,082
JBrowse link
G Slc40a1 solute carrier family 40 member 1 increases expression ISO Isoproterenol results in increased expression of SLC40A1 mRNA CTD PMID:20003209 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
G Slc43a3 solute carrier family 43, member 3 increases expression ISO Isoproterenol results in increased expression of SLC43A3 mRNA CTD PMID:20003209 NCBI chr 3:70,008,160...70,030,324
Ensembl chr 3:70,009,313...70,029,749
JBrowse link
G Slc45a3 solute carrier family 45, member 3 increases expression ISO Isoproterenol results in increased expression of SLC45A3 mRNA CTD PMID:20003209 NCBI chr13:43,407,293...43,427,588
Ensembl chr13:43,407,293...43,427,588
JBrowse link
G Slc6a1 solute carrier family 6 member 1 increases expression
multiple interactions
ISO Isoproterenol results in increased expression of SLC6A1 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Isoproterenol results in increased expression of SLC6A1 protein]
CTD PMID:30170018 NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Isoproterenol results in increased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Slc8a1 solute carrier family 8 member A1 multiple interactions
increases expression
ISO
EXP
EGR1 protein affects the reaction [[Isoproterenol co-treated with Phenylephrine] results in increased expression of SLC8A1 mRNA]; EGR1 protein affects the reaction [[Isoproterenol co-treated with Phenylephrine] results in increased expression of SLC8A1 protein]; Propranolol inhibits the reaction [[Isoproterenol co-treated with Phenylephrine] results in increased expression of SLC8A1 protein]
Isoproterenol results in increased expression of SLC8A1 mRNA
CTD PMID:11179087 PMID:15621046 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628
JBrowse link
G Slco3a1 solute carrier organic anion transporter family, member 3a1 increases expression ISO Isoproterenol results in increased expression of SLCO3A1 mRNA CTD PMID:20003209 NCBI chr 1:128,106,232...128,388,043
Ensembl chr 1:128,106,228...128,387,925
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Isoproterenol results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
JBrowse link
G Smad1 SMAD family member 1 decreases expression ISO Isoproterenol results in decreased expression of SMAD1 mRNA CTD PMID:21335049 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651
JBrowse link
G Smad2 SMAD family member 2 increases expression EXP Isoproterenol results in increased expression of SMAD2 mRNA CTD PMID:35014750 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Smad3 SMAD family member 3 increases expression EXP Isoproterenol results in increased expression of SMAD3 mRNA CTD PMID:35014750 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smap1 small ArfGAP 1 increases expression ISO Isoproterenol results in increased expression of SMAP1 mRNA CTD PMID:20003209 NCBI chr 9:26,250,178...26,342,151
Ensembl chr 9:26,249,978...26,342,170
JBrowse link
G Smarca1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 increases expression ISO Isoproterenol results in increased expression of SMARCA1 mRNA CTD PMID:20003209 NCBI chr  X:126,980,201...127,066,385
Ensembl chr  X:126,994,947...127,066,347
JBrowse link
G Smc5 structural maintenance of chromosomes 5 increases expression ISO Isoproterenol results in increased expression of SMC5 mRNA CTD PMID:20003209 NCBI chr 1:220,769,366...220,839,138
Ensembl chr 1:220,769,366...220,839,096
JBrowse link
G Smoc2 SPARC related modular calcium binding 2 decreases expression ISO Isoproterenol results in decreased expression of SMOC2 mRNA CTD PMID:20003209 NCBI chr 1:55,262,472...55,391,804
Ensembl chr 1:55,262,530...55,391,693
JBrowse link
G Smtn smoothelin decreases expression ISO Isoproterenol results in decreased expression of SMTN mRNA CTD PMID:20003209 NCBI chr14:78,398,595...78,420,908
Ensembl chr14:78,397,778...78,420,886
JBrowse link
G Smurf2 SMAD specific E3 ubiquitin protein ligase 2 increases expression ISO Isoproterenol results in increased expression of SMURF2 mRNA CTD PMID:20003209 NCBI chr10:91,761,798...91,862,485
Ensembl chr10:91,761,807...91,862,488
JBrowse link
G Smyd1 SET and MYND domain containing 1 multiple interactions
decreases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in decreased expression of SMYD1 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 4:103,195,330...103,252,989
Ensembl chr 4:103,200,322...103,311,766
JBrowse link
G Snapin SNAP-associated protein decreases expression ISO Isoproterenol results in decreased expression of SNAPIN mRNA CTD PMID:20003209 NCBI chr 2:175,971,575...175,974,164
Ensembl chr 2:175,971,257...175,974,231
JBrowse link
G Snrpb small nuclear ribonucleoprotein polypeptides B and B1 decreases expression ISO Isoproterenol results in decreased expression of SNRPB mRNA CTD PMID:21335049 NCBI chr 3:117,369,816...117,379,344
Ensembl chr 3:117,370,100...117,379,339
JBrowse link
G Snrpf small nuclear ribonucleoprotein polypeptide F decreases expression ISO Isoproterenol results in decreased expression of SNRPF mRNA CTD PMID:20003209 NCBI chr 7:28,130,427...28,137,129
Ensembl chr 7:28,130,427...28,137,129
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of SOCS3 mRNA] CTD PMID:18089841 PMID:20003209 PMID:21335049 PMID:21823215 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Sod1 superoxide dismutase 1 increases expression
affects binding
multiple interactions
decreases activity
EXP
ISO
Isoproterenol results in increased expression of SOD1 protein
Isoproterenol binds to SOD1 protein; Isoproterenol binds to SOD1 protein mutant form
benidipine inhibits the reaction [Isoproterenol results in decreased activity of SOD1 protein]; Carvedilol inhibits the reaction [Isoproterenol results in decreased expression of and results in decreased activity of SOD1 protein]; imetit inhibits the reaction [Isoproterenol results in decreased expression of and results in decreased activity of SOD1 protein]; Isoproterenol results in decreased expression of and results in decreased activity of SOD1 protein
CTD PMID:16702995 PMID:23612299 PMID:25269373 PMID:25496245 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO
EXP
[ADCY5 protein results in increased susceptibility to Isoproterenol] which results in decreased expression of SOD2 protein; SOD2 protein inhibits the reaction [ADCY5 protein results in increased susceptibility to Isoproterenol]
[Isoproterenol co-treated with POSTN protein] results in decreased expression of SOD2 mRNA
CTD PMID:23536361 PMID:30303030 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 increases expression ISO Isoproterenol results in increased expression of SORBS1 mRNA CTD PMID:20003209 NCBI chr 1:239,107,882...239,330,276
Ensembl chr 1:239,108,777...239,330,169
JBrowse link
G Sorbs3 sorbin and SH3 domain containing 3 increases expression ISO Isoproterenol results in increased expression of SORBS3 mRNA CTD PMID:20003209 NCBI chr15:45,252,921...45,284,758
Ensembl chr15:45,253,379...45,284,758
JBrowse link
G Sorcs2 sortilin-related VPS10 domain containing receptor 2 decreases expression ISO Isoproterenol results in decreased expression of SORCS2 mRNA CTD PMID:20003209 NCBI chr14:74,371,089...74,735,943
Ensembl chr14:74,371,415...74,735,943
JBrowse link
G Sord sorbitol dehydrogenase decreases expression ISO Isoproterenol results in decreased expression of SORD mRNA CTD PMID:21335049 NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133
JBrowse link
G Sox17 SRY-box transcription factor 17 increases expression ISO Isoproterenol results in increased expression of SOX17 mRNA CTD PMID:20003209 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228
JBrowse link
G Sox6 SRY-box transcription factor 6 decreases expression
multiple interactions
ISO Isoproterenol results in decreased expression of SOX6 mRNA; Isoproterenol results in decreased expression of SOX6 protein
JUNB protein promotes the reaction [Isoproterenol results in decreased expression of SOX6 mRNA]; JUNB protein promotes the reaction [Isoproterenol results in decreased expression of SOX6 protein]
CTD PMID:21177286 NCBI chr 1:169,723,306...170,334,846
Ensembl chr 1:169,729,194...170,277,386
JBrowse link
G Sox9 SRY-box transcription factor 9 multiple interactions
increases expression
ISO bellidifolin inhibits the reaction [Isoproterenol results in increased expression of SOX9 protein] CTD PMID:35586685 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of SP1 mRNA; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of SP1 mRNA] CTD PMID:10710348 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
JBrowse link
G Spag9 sperm associated antigen 9 increases expression ISO Isoproterenol results in increased expression of SPAG9 mRNA CTD PMID:20003209 NCBI chr10:78,943,439...79,077,797
Ensembl chr10:78,943,479...79,077,797
JBrowse link
G Sphk1 sphingosine kinase 1 increases expression ISO Isoproterenol results in increased expression of SPHK1 mRNA CTD PMID:20003209 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240
JBrowse link
G Sphk2 sphingosine kinase 2 decreases expression ISO Isoproterenol results in decreased expression of SPHK2 mRNA CTD PMID:20003209 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391
JBrowse link
G Spns2 SPNS lysolipid transporter 2, sphingosine-1-phosphate increases expression ISO Isoproterenol results in increased expression of SPNS2 mRNA CTD PMID:20003209 NCBI chr10:57,067,348...57,105,969
Ensembl chr10:57,066,897...57,105,957
JBrowse link
G Spock2 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2 increases expression ISO Isoproterenol results in increased expression of SPOCK2 mRNA CTD PMID:20003209 NCBI chr20:28,037,334...28,064,272
Ensembl chr20:28,033,475...28,064,272
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression
decreases expression
ISO
EXP
Isoproterenol results in increased expression of SPP1 mRNA
Isoproterenol results in decreased expression of SPP1 mRNA
CTD PMID:20003209 PMID:20211217 PMID:21335049 PMID:23558518 PMID:24286936 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Spsb1 splA/ryanodine receptor domain and SOCS box containing 1 increases expression ISO Isoproterenol results in increased expression of SPSB1 mRNA CTD PMID:20003209 NCBI chr 5:160,358,292...160,418,541
Ensembl chr 5:160,358,308...160,418,468
JBrowse link
G Spta1 spectrin, alpha, erythrocytic 1 decreases expression ISO Isoproterenol results in decreased expression of SPTA1 mRNA CTD PMID:20003209 NCBI chr13:86,203,504...86,279,371
Ensembl chr13:86,203,504...86,279,371
JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 increases expression ISO Isoproterenol results in increased expression of SPTLC2 mRNA CTD PMID:20003209 NCBI chr 6:106,948,682...107,031,532
Ensembl chr 6:106,950,949...107,031,542
JBrowse link
G Sqle squalene epoxidase increases expression ISO Isoproterenol results in increased expression of SQLE mRNA CTD PMID:21335049 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO Isoproterenol results in increased expression of SQSTM1 mRNA CTD PMID:20003209 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Srm spermidine synthase increases expression ISO Isoproterenol results in increased expression of SRM mRNA CTD PMID:21335049 NCBI chr 5:159,025,875...159,029,076
Ensembl chr 5:159,025,873...159,029,405
JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 decreases expression ISO Isoproterenol results in decreased expression of SRSF2 mRNA CTD PMID:20003209 NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338
JBrowse link
G St7l suppression of tumorigenicity 7-like increases expression ISO Isoproterenol results in increased expression of ST7L mRNA CTD PMID:20003209 NCBI chr 2:192,364,594...192,434,414
Ensembl chr 2:192,364,594...192,487,190
JBrowse link
G St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 increases expression ISO Isoproterenol results in increased expression of ST8SIA6 mRNA CTD PMID:20003209 NCBI chr17:76,740,755...76,884,178
Ensembl chr17:76,745,224...76,884,299
JBrowse link
G Stard5 StAR-related lipid transfer domain containing 5 increases expression ISO Isoproterenol results in increased expression of STARD5 mRNA CTD PMID:20003209 NCBI chr 1:137,606,151...137,616,017
Ensembl chr 1:137,606,177...137,616,469
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of STAT1 mRNA CTD PMID:30303030 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Stat3 signal transducer and activator of transcription 3 affects localization
multiple interactions
increases expression
increases phosphorylation
EXP
ISO
Isoproterenol affects the localization of STAT3 protein
[Isoproterenol co-treated with POSTN protein] results in decreased expression of STAT3 mRNA; Betaine promotes the reaction [Isoproterenol results in increased phosphorylation of STAT3 protein]; Cyclosporine inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein]; Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein; Verapamil inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein]
Isoproterenol results in increased expression of STAT3; Isoproterenol results in increased expression of STAT3 protein
Isoproterenol results in increased expression of STAT3 mRNA
STAT3 protein affects the reaction [BMP10 protein results in decreased susceptibility to Isoproterenol]
STAT3 protein affects the reaction [BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]]
CTD PMID:19299911 PMID:21335049 PMID:25080425 PMID:29355689 PMID:30303030 More... NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stat5a signal transducer and activator of transcription 5A decreases expression ISO Isoproterenol results in decreased expression of STAT5A mRNA CTD PMID:20003209 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
JBrowse link
G Stc1 stanniocalcin 1 increases expression ISO Isoproterenol results in increased expression of STC1 mRNA CTD PMID:20003209 NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264
JBrowse link
G Ston1 stonin 1 increases expression ISO Isoproterenol results in increased expression of STON1 mRNA CTD PMID:20003209 NCBI chr 6:5,843,186...5,892,557
Ensembl chr 6:5,843,185...5,892,449
JBrowse link
G Stt3a STT3 oligosaccharyltransferase complex catalytic subunit A increases expression ISO Isoproterenol results in increased expression of STT3A mRNA CTD PMID:21823215 NCBI chr 8:36,443,623...36,483,111
Ensembl chr 8:36,446,788...36,483,293
JBrowse link
G Stx3 syntaxin 3 increases expression ISO Isoproterenol results in increased expression of STX3 mRNA CTD PMID:20003209 NCBI chr 1:208,617,018...208,686,240
Ensembl chr 1:208,639,115...208,685,805
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 decreases expression ISO Isoproterenol results in decreased expression of SULT1B1 mRNA CTD PMID:21335049 NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483
JBrowse link
G Syk spleen associated tyrosine kinase increases expression ISO Isoproterenol results in increased expression of SYK mRNA CTD PMID:20003209 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
JBrowse link
G Syn2 synapsin II increases expression ISO Isoproterenol results in increased expression of SYN2 mRNA CTD PMID:20003209 NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192
JBrowse link
G Syt12 synaptotagmin 12 increases expression ISO Isoproterenol results in increased expression of SYT12 mRNA CTD PMID:20003209 NCBI chr 1:201,729,307...201,760,192
Ensembl chr 1:201,730,371...201,759,609
JBrowse link
G Tac1 tachykinin, precursor 1 affects response to substance EXP TAC1 protein affects the susceptibility to Isoproterenol CTD PMID:11270094 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Tacc2 transforming, acidic coiled-coil containing protein 2 increases expression ISO Isoproterenol results in increased expression of TACC2 mRNA CTD PMID:20003209 NCBI chr 1:185,139,223...185,327,881
Ensembl chr 1:185,116,111...185,327,881
JBrowse link
G Tax1bp1 Tax1 binding protein 1 increases expression ISO Isoproterenol results in increased expression of TAX1BP1 mRNA CTD PMID:20003209 NCBI chr 4:81,821,991...81,877,906
Ensembl chr 4:81,821,989...81,879,100
JBrowse link
G Tbc1d15 TBC1 domain family, member 15 increases expression ISO Isoproterenol results in increased expression of TBC1D15 mRNA CTD PMID:20003209 NCBI chr 7:50,804,553...50,860,272
Ensembl chr 7:50,804,012...50,860,175
JBrowse link
G Tbk1 TANK-binding kinase 1 increases expression
multiple interactions
ISO
EXP
Isoproterenol results in increased expression of TBK1 mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of TBK1 mRNA
CTD PMID:20003209 PMID:30303030 NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892
JBrowse link
G Tbl1xr1 TBL1X/Y related 1 increases expression ISO Isoproterenol results in increased expression of TBL1XR1 mRNA CTD PMID:20003209 NCBI chr 2:104,788,950...104,929,055
Ensembl chr 2:104,801,721...104,929,055
JBrowse link
G Tcf23 transcription factor 23 increases expression ISO Isoproterenol results in increased expression of TCF23 mRNA CTD PMID:20003209 NCBI chr 6:25,397,889...25,406,639
Ensembl chr 6:25,397,937...25,405,880
JBrowse link
G Tcf3 transcription factor 3 decreases expression ISO Isoproterenol results in decreased expression of TCF3 mRNA CTD PMID:20003209 NCBI chr 7:9,280,571...9,302,315
Ensembl chr 7:9,280,571...9,302,314
JBrowse link
G Tcn2 transcobalamin 2 increases expression ISO Isoproterenol results in increased expression of TCN2 mRNA CTD PMID:20003209 NCBI chr14:78,813,343...78,828,549
Ensembl chr14:78,813,343...78,828,489
JBrowse link
G Tdg thymine-DNA glycosylase increases expression ISO Isoproterenol results in increased expression of TDG mRNA CTD PMID:21335049 NCBI chr 7:21,077,853...21,097,617
Ensembl chr 7:21,077,853...21,097,567
JBrowse link
G Tecrl trans-2,3-enoyl-CoA reductase-like increases expression ISO Isoproterenol results in increased expression of TECRL mRNA CTD PMID:20003209 NCBI chr14:24,732,241...24,805,272
Ensembl chr14:24,732,241...24,805,272
JBrowse link
G Tfdp2 transcription factor Dp-2 increases expression ISO Isoproterenol results in increased expression of TFDP2 mRNA CTD PMID:20003209 NCBI chr 8:96,760,459...96,901,466
Ensembl chr 8:96,760,504...96,896,682
JBrowse link
G Tfrc transferrin receptor decreases expression ISO Isoproterenol results in decreased expression of TFRC protein
Isoproterenol results in decreased expression of TFRC mRNA
CTD PMID:2989362 PMID:20003209 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression
multiple interactions
increases expression
increases expression
ISO
EXP
Isoproterenol results in decreased expression of TGFB1 mRNA
BAY 58-2667 inhibits the reaction [Isoproterenol results in increased expression of TGFB1 mRNA]; Glyburide promotes the reaction [Isoproterenol results in increased expression of TGFB1 protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased expression of TGFB1 protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of TGFB1 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of TGFB1 protein]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of TGFB1 mRNA]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of TGFB1 protein]; Rutin inhibits the reaction [Isoproterenol results in increased expression of TGFB1 mRNA]; Rutin inhibits the reaction [Isoproterenol results in increased expression of TGFB1 protein]
Isoproterenol results in increased expression of TGFB1 mRNA; Isoproterenol results in increased expression of TGFB1 protein
celastrol methyl ester inhibits the reaction [Isoproterenol results in increased expression of TGFB1 mRNA]; osthol inhibits the reaction [Isoproterenol results in increased expression of TGFB1 mRNA]; osthol inhibits the reaction [Isoproterenol results in increased expression of TGFB1 protein]
isoprenaline increases expression of Tgfb1 protein in blood serum
CTD
RGD
PMID:11821714 PMID:19667237 PMID:21854795 PMID:24117263 PMID:35014750 More... RGD:156430318 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression EXP Isoproterenol results in increased expression of TGFB2 mRNA CTD PMID:20211217 PMID:23558518 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of TGFBR2 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Tgm2 transglutaminase 2 increases expression ISO Isoproterenol results in increased expression of TGM2 mRNA CTD PMID:20003209 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
JBrowse link
G Thbs2 thrombospondin 2 increases expression ISO Isoproterenol results in increased expression of THBS2 mRNA CTD PMID:20003209 NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789
JBrowse link
G Thoc3 THO complex subunit 3 decreases expression ISO Isoproterenol results in decreased expression of THOC3 mRNA CTD PMID:20003209 NCBI chr17:10,143,184...10,152,375
Ensembl chr17:10,143,139...10,152,370
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions
increases expression
EXP [Isoproterenol co-treated with Amiodarone] results in increased expression of THRA mRNA alternative form
Isoproterenol results in increased expression of THRA mRNA alternative form
CTD PMID:7598731 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions
increases expression
EXP [Isoproterenol co-treated with Amiodarone] results in increased expression of THRB mRNA alternative form; Amiodarone inhibits the reaction [Isoproterenol results in increased expression of THRB mRNA alternative form] CTD PMID:7598731 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Thy1 Thy-1 cell surface antigen decreases expression
multiple interactions
ISO Isoproterenol results in decreased expression of THY1
Propranolol inhibits the reaction [Isoproterenol results in decreased expression of THY1]
CTD PMID:7558147 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 increases expression EXP Isoproterenol results in increased expression of TIAM1 mRNA CTD PMID:20211217 NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
decreases expression
ISO
EXP
Isoproterenol results in increased expression of TIMP1 mRNA
Isoproterenol results in decreased expression of TIMP1 mRNA
Isoproterenol results in increased expression of TIMP1 mRNA; Isoproterenol results in increased expression of TIMP1 protein
CTD PMID:20003209 PMID:20211217 PMID:23558518 PMID:24286936 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 increases expression
multiple interactions
decreases expression
ISO
EXP
Isoproterenol results in increased expression of TIMP3 protein
natakalim inhibits the reaction [Isoproterenol results in decreased expression of TIMP3 protein]
CTD PMID:24286936 PMID:27890915 NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839
JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 increases expression
decreases expression
ISO Isoproterenol results in increased expression of TIMP4 mRNA
Isoproterenol results in decreased expression of TIMP4 protein
CTD PMID:20003209 PMID:24286936 NCBI chr 4:148,306,021...148,312,558
Ensembl chr 4:148,304,490...148,312,558
JBrowse link
G Tinagl1 tubulointerstitial nephritis antigen-like 1 increases expression ISO Isoproterenol results in increased expression of TINAGL1 mRNA CTD PMID:20003209 NCBI chr 5:142,513,710...142,523,730
Ensembl chr 5:142,513,714...142,523,720
JBrowse link
G Tk1 thymidine kinase 1 decreases expression ISO Isoproterenol results in decreased expression of TK1 mRNA CTD PMID:21335049 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
JBrowse link
G Tle1 TLE family member 1, transcriptional corepressor increases expression ISO Isoproterenol results in increased expression of TLE1 mRNA CTD PMID:20003209 NCBI chr 5:85,851,827...85,934,806
Ensembl chr 5:85,851,827...85,934,774
JBrowse link
G Tlr4 toll-like receptor 4 increases expression
multiple interactions
ISO
EXP
Isoproterenol results in increased expression of TLR4 mRNA
Isoproterenol results in increased expression of TLR4 mRNA; Isoproterenol results in increased expression of TLR4 protein
anethole inhibits the reaction [Isoproterenol results in increased expression of TLR4 mRNA]; anethole inhibits the reaction [Isoproterenol results in increased expression of TLR4 protein]; Metformin inhibits the reaction [Isoproterenol results in increased expression of TLR4 mRNA]
CTD PMID:20003209 PMID:24842192 PMID:35430261 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 increases expression ISO Isoproterenol results in increased expression of TMBIM1 mRNA CTD PMID:20003209 NCBI chr 9:75,871,835...75,889,366
Ensembl chr 9:75,871,835...75,889,069
JBrowse link
G Tmcc3 transmembrane and coiled-coil domain family 3 increases expression ISO Isoproterenol results in increased expression of TMCC3 mRNA CTD PMID:20003209 NCBI chr 7:28,893,972...29,171,935
Ensembl chr 7:28,893,967...29,171,926
JBrowse link
G Tmem140 transmembrane protein 140 increases expression ISO Isoproterenol results in increased expression of TMEM140 mRNA CTD PMID:20003209 NCBI chr 4:63,536,477...63,547,478
Ensembl chr 4:63,536,168...63,548,455
JBrowse link
G Tmem141 transmembrane protein 141 decreases expression ISO Isoproterenol results in decreased expression of TMEM141 mRNA CTD PMID:20003209 NCBI chr 3:8,439,533...8,441,491
Ensembl chr 3:8,439,533...8,441,491
JBrowse link
G Tmem144 transmembrane protein 144 increases expression ISO Isoproterenol results in increased expression of TMEM144 mRNA CTD PMID:20003209 NCBI chr 2:164,960,649...164,993,562
Ensembl chr 2:164,961,247...164,992,368
JBrowse link
G Tmem164 transmembrane protein 164 increases expression ISO Isoproterenol results in increased expression of TMEM164 mRNA CTD PMID:20003209 NCBI chr  X:106,288,019...106,448,642
Ensembl chr  X:106,289,371...106,448,640
JBrowse link
G Tmem176a transmembrane protein 176A increases expression ISO Isoproterenol results in increased expression of TMEM176A mRNA CTD PMID:20003209 NCBI chr 4:77,774,940...77,778,620
Ensembl chr 4:77,774,843...77,778,620
JBrowse link
G Tmem38b transmembrane protein 38B increases expression ISO Isoproterenol results in increased expression of TMEM38B mRNA CTD PMID:20003209 NCBI chr 5:68,460,304...68,496,026
Ensembl chr 5:68,460,304...68,496,025
JBrowse link
G Tmod4 tropomodulin 4 decreases expression ISO Isoproterenol results in decreased expression of TMOD4 mRNA CTD PMID:20003209 NCBI chr 2:182,695,709...182,700,540
Ensembl chr 2:182,695,709...182,700,540
JBrowse link
G Tmsb4x thymosin beta 4, X-linked decreases expression ISO Isoproterenol results in decreased expression of TMSB4X mRNA CTD PMID:21335049 NCBI chr  X:27,144,666...27,146,667
Ensembl chr  X:27,128,610...27,146,667
JBrowse link
G Tmtc1 transmembrane O-mannosyltransferase targeting cadherins 1 increases expression ISO Isoproterenol results in increased expression of TMTC1 mRNA CTD PMID:20003209 NCBI chr 4:181,142,937...181,357,979
Ensembl chr 4:181,146,251...181,359,289
JBrowse link
G Tmx1 thioredoxin-related transmembrane protein 1 decreases expression ISO Isoproterenol results in decreased expression of TMX1 mRNA CTD PMID:20003209 NCBI chr 6:88,960,691...88,971,744
Ensembl chr 6:88,960,695...88,971,301
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
decreases expression
increases secretion
ISO
EXP
Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Isoproterenol inhibits the reaction [TNF protein results in increased secretion of SELE mRNA]
bellidifolin inhibits the reaction [Isoproterenol results in increased expression of TNF mRNA]; Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; SB 206553 inhibits the reaction [Isoproterenol results in increased expression of TNF]; ZD 7155 inhibits the reaction [Isoproterenol results in increased expression of TNF protein]
5-Methoxypsoralen inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; [Isoproterenol co-treated with POSTN protein] results in increased expression of TNF mRNA; anethole inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; Apigenin inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; bellidifolin inhibits the reaction [Isoproterenol results in increased expression of TNF mRNA]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of TNF mRNA]; Enalapril inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; erdosteine inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; ferruginol inhibits the reaction [Isoproterenol results in increased secretion of TNF protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; Glyburide promotes the reaction [Isoproterenol results in increased expression of TNF protein]; Hesperidin inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; ICI 118551 inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; ICI 118551 inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; Isoproterenol inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; Isoproterenol inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]; Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Isoproterenol results in increased expression of and results in increased secretion of TNF protein; mangiferin inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; mangostin inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; Metformin inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of TNF protein]; Metformin inhibits the reaction [Isoproterenol results in increased expression of TNF mRNA]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; punicalagin inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of TNF protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of TNF mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADL mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADM mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT1B mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT2 mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARA mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARA protein]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARGC1A mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARGC1A protein]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL2 mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL2 protein]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of TNF mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of TNF protein]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased phosphorylation of MTOR protein]]; Tretinoin inhibits the reaction [Isoproterenol results in increased expression of TNF protein]
Isoproterenol results in increased expression of TNF; Isoproterenol results in increased expression of TNF mRNA
Isoproterenol results in decreased expression of TNF mRNA
Isoproterenol results in increased expression of TNF mRNA; Isoproterenol results in increased expression of TNF protein
CTD PMID:8096834 PMID:8780174 PMID:9038718 PMID:9688336 PMID:10525314 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 decreases expression ISO Isoproterenol results in decreased expression of TNFAIP6 mRNA CTD PMID:32816093 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A increases expression ISO Isoproterenol results in increased expression of TNFRSF12A mRNA CTD PMID:21335049 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A decreases expression
increases expression
ISO
EXP
Isoproterenol results in decreased expression of TNFRSF1A mRNA
Isoproterenol results in increased expression of TNFRSF1A mRNA
CTD PMID:24286936 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases expression EXP Isoproterenol results in increased expression of TNFSF10 mRNA CTD PMID:24286936 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tnik TRAF2 and NCK interacting kinase increases expression ISO Isoproterenol results in increased expression of TNIK mRNA CTD PMID:20003209 NCBI chr 2:111,184,352...111,587,993
Ensembl chr 2:111,184,387...111,580,750
JBrowse link
G Tnks tankyrase increases expression ISO Isoproterenol results in increased expression of TNKS mRNA CTD PMID:20003209 NCBI chr16:57,223,174...57,370,740
Ensembl chr16:57,225,094...57,366,260
JBrowse link
G Tnni3 troponin I3, cardiac type increases expression
increases secretion
multiple interactions
ISO
EXP
Isoproterenol results in increased expression of TNNI3 protein
Isoproterenol results in increased secretion of TNNI3 protein
5-Methoxypsoralen inhibits the reaction [Isoproterenol results in increased expression of TNNI3 protein]; anethole inhibits the reaction [Isoproterenol results in increased expression of TNNI3 protein]; ferruginol inhibits the reaction [Isoproterenol results in increased expression of TNNI3 protein]; Glyburide promotes the reaction [Isoproterenol results in increased expression of TNNI3 protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of TNNI3 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of TNNI3 protein]; Quercetin inhibits the reaction [Isoproterenol results in increased secretion of TNNI3 protein]; Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of TNNI3 protein]; thymoquinone inhibits the reaction [Isoproterenol results in increased secretion of TNNI3 protein]; Tretinoin inhibits the reaction [Isoproterenol results in increased expression of TNNI3 protein]; xanthone inhibits the reaction [Isoproterenol results in increased expression of TNNI3 protein]
CTD PMID:17654401 PMID:19549929 PMID:19854236 PMID:22878004 PMID:24286936 More... NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580
JBrowse link
G Tnnt1 troponin T1, slow skeletal type multiple interactions EXP Isoproterenol results in increased expression of and results in increased secretion of TNNT1 protein; oleuropein inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of TNNT1 protein] CTD PMID:26056852 NCBI chr 1:69,306,362...69,316,721
Ensembl chr 1:69,306,362...69,316,721
JBrowse link
G Tnnt2 troponin T2, cardiac type affects expression
increases expression
increases secretion
multiple interactions
decreases expression
EXP Isoproterenol affects the expression of TNNT2 protein
Isoproterenol results in increased expression of TNNT2 protein
Isoproterenol results in increased secretion of TNNT2 protein
5-Methoxypsoralen inhibits the reaction [Isoproterenol results in increased expression of TNNT2 protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of TNNT2 protein]; ferruginol inhibits the reaction [Isoproterenol results in increased expression of TNNT2 protein]; Gallic Acid inhibits the reaction [Isoproterenol results in increased secretion of TNNT2 protein]; Lutein inhibits the reaction [Isoproterenol results in decreased expression of TNNT2 protein]; naringin inhibits the reaction [Isoproterenol results in increased expression of TNNT2 protein]; Quercetin inhibits the reaction [Isoproterenol results in increased secretion of TNNT2 protein]; Vincristine inhibits the reaction [Isoproterenol results in increased secretion of TNNT2 protein]
CTD PMID:17188415 PMID:17654401 PMID:17848144 PMID:19146839 PMID:19812120 More... NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388
JBrowse link
G Tnpo1 transportin 1 increases expression ISO Isoproterenol results in increased expression of TNPO1 mRNA CTD PMID:20003209 NCBI chr 2:30,207,529...30,300,162
Ensembl chr 2:30,211,510...30,300,375
JBrowse link
G Tp53 tumor protein p53 increases expression
decreases expression
multiple interactions
EXP
ISO
Isoproterenol results in increased expression of TP53 protein
Isoproterenol results in increased expression of TP53 mRNA
Isoproterenol results in decreased expression of TP53 mRNA
Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of and results in increased phosphorylation of TP53 protein]; Isoproterenol results in increased expression of and results in increased phosphorylation of TP53 protein; pifithrin inhibits the reaction [Isoproterenol results in increased expression of and results in increased phosphorylation of TP53 protein]; S100A9 protein affects the reaction [Isoproterenol results in increased expression of and results in increased phosphorylation of TP53 protein]
CTD PMID:19466570 PMID:24286936 PMID:32924446 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of TRP53INP1 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968
JBrowse link
G Tpm1 tropomyosin 1 decreases expression ISO Isoproterenol results in decreased expression of TPM1 mRNA CTD PMID:20003209 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
JBrowse link
G Tpo thyroid peroxidase decreases activity EXP Isoproterenol results in decreased activity of TPO protein CTD PMID:26884060 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199
JBrowse link
G Trak1 trafficking kinesin protein 1 decreases expression ISO Isoproterenol results in decreased expression of TRAK1 mRNA CTD PMID:20003209 NCBI chr 8:120,984,445...121,139,357
Ensembl chr 8:120,984,431...121,139,367
JBrowse link
G Trim7 tripartite motif-containing 7 decreases expression ISO Isoproterenol results in decreased expression of TRIM7 mRNA CTD PMID:20003209 NCBI chr10:33,205,491...33,221,482
Ensembl chr10:33,205,491...33,221,468
JBrowse link
G Trmt5 tRNA methyltransferase 5 increases expression ISO Isoproterenol results in increased expression of TRMT5 mRNA CTD PMID:20003209 NCBI chr 6:91,963,558...91,987,660
Ensembl chr 6:91,943,724...91,987,555
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 increases expression ISO Isoproterenol results in increased expression of TSC22D3 mRNA CTD PMID:20003209 NCBI chr  X:104,217,898...104,277,886
Ensembl chr  X:104,217,925...104,276,861
JBrowse link
G Tsc22d4 TSC22 domain family, member 4 decreases expression ISO Isoproterenol results in decreased expression of TSC22D4 mRNA CTD PMID:20003209 NCBI chr12:18,939,150...18,952,008
Ensembl chr12:18,914,398...18,952,008
JBrowse link
G Tsfm Ts translation elongation factor, mitochondrial decreases expression ISO Isoproterenol results in decreased expression of TSFM mRNA CTD PMID:20003209 NCBI chr 7:62,828,997...62,864,784
Ensembl chr 7:62,845,488...62,864,769
JBrowse link
G Tspyl4 TSPY-like 4 increases expression ISO Isoproterenol results in increased expression of TSPYL4 mRNA CTD PMID:20003209 NCBI chr20:38,098,756...38,100,752
Ensembl chr20:38,098,677...38,103,053
JBrowse link
G Ttll7 tubulin tyrosine ligase like 7 increases expression ISO Isoproterenol results in increased expression of TTLL7 mRNA CTD PMID:20003209 NCBI chr 2:235,765,786...235,889,047
Ensembl chr 2:235,765,835...235,885,047
JBrowse link
G Ttr transthyretin increases expression ISO Isoproterenol results in increased expression of TTR mRNA CTD PMID:20003209 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
JBrowse link
G Tuba1b tubulin, alpha 1B decreases expression ISO Isoproterenol results in decreased expression of TUBA1B mRNA CTD PMID:20003209 NCBI chr 7:130,090,663...130,093,644
Ensembl chr 7:130,081,032...130,196,186
JBrowse link
G Tuba4a tubulin, alpha 4A decreases expression ISO Isoproterenol results in decreased expression of TUBA4A mRNA CTD PMID:20003209 NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918
JBrowse link
G Tuba8 tubulin, alpha 8 decreases expression ISO Isoproterenol results in decreased expression of TUBA8 mRNA CTD PMID:20003209 NCBI chr 4:154,440,045...154,456,918
Ensembl chr 4:154,440,074...154,456,917
JBrowse link
G Tubb2a tubulin, beta 2A class IIa decreases expression ISO Isoproterenol results in decreased expression of TUBB2A mRNA CTD PMID:20003209 NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression ISO Isoproterenol results in decreased expression of TUBB5 mRNA CTD PMID:20003209 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Tubb6 tubulin, beta 6 class V increases expression EXP Isoproterenol results in increased expression of TUBB6 mRNA CTD PMID:20211217 NCBI chr18:60,943,394...60,953,031
Ensembl chr18:60,943,375...60,954,418
JBrowse link
G Txn1 thioredoxin 1 decreases expression
multiple interactions
ISO
EXP
Isoproterenol results in decreased expression of TXN1 mRNA
Lutein inhibits the reaction [Isoproterenol results in decreased expression of TXN protein]
CTD PMID:21335049 PMID:34435724 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Txndc5 thioredoxin domain containing 5 decreases expression ISO Isoproterenol results in decreased expression of TXNDC5 mRNA CTD PMID:20003209 NCBI chr17:26,289,880...26,318,025
Ensembl chr17:26,289,880...26,318,025
JBrowse link
G Txnip thioredoxin interacting protein increases expression
multiple interactions
EXP Isoproterenol results in increased expression of TXNIP protein
Lutein inhibits the reaction [Isoproterenol results in increased expression of TXNIP protein]
CTD PMID:34435724 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Txnrd2 thioredoxin reductase 2 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of TXNRD2 mRNA CTD PMID:30303030 NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
JBrowse link
G Tyw1 tRNA-yW synthesizing protein 1 homolog increases expression ISO Isoproterenol results in increased expression of TYW1 mRNA CTD PMID:20003209 NCBI chr12:26,332,020...26,418,286
Ensembl chr12:26,330,351...26,418,208
JBrowse link
G U2af1 U2 small nuclear RNA auxiliary factor 1 decreases expression ISO Isoproterenol results in decreased expression of U2AF1 mRNA CTD PMID:20003209 NCBI chr20:9,742,904...9,753,840
Ensembl chr20:9,742,905...9,753,832
JBrowse link
G Uap1 UDP-N-acetylglucosamine pyrophosphorylase 1 increases expression ISO Isoproterenol results in increased expression of UAP1 mRNA CTD PMID:20003209 NCBI chr13:82,342,946...82,377,558
Ensembl chr13:82,342,946...82,377,469
JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of UBA1 mRNA CTD PMID:30303030 NCBI chr  X:1,508,700...1,530,677
Ensembl chr  X:1,508,666...1,530,636
JBrowse link
G Ubb ubiquitin B increases expression ISO Isoproterenol results in increased expression of UBB mRNA CTD PMID:21335049 NCBI chr10:47,247,630...47,249,335
Ensembl chr10:47,245,637...47,249,333
JBrowse link
G Ubc ubiquitin C decreases expression ISO Isoproterenol results in decreased expression of UBC mRNA CTD PMID:20003209 NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925
JBrowse link
G Ube2d1 ubiquitin-conjugating enzyme E2D 1 increases expression EXP Isoproterenol results in increased expression of UBE2D1 mRNA CTD PMID:30303030 NCBI chr20:17,309,315...17,343,770
Ensembl chr20:17,309,315...17,342,295
JBrowse link
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 increases expression ISO Isoproterenol results in increased expression of UBR2 mRNA CTD PMID:20003209 NCBI chr 9:13,982,427...14,062,315
Ensembl chr 9:13,982,329...14,062,139
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 increases expression ISO Isoproterenol results in increased expression of UCHL1 mRNA CTD PMID:20003209 NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590
JBrowse link
G Uck2 uridine-cytidine kinase 2 increases expression EXP Isoproterenol results in increased expression of UCK2 mRNA CTD PMID:20211217 NCBI chr13:79,380,807...79,438,121
Ensembl chr13:79,383,846...79,438,352
JBrowse link
G Ucp1 uncoupling protein 1 increases expression EXP Isoproterenol results in increased expression of UCP1 protein CTD PMID:17250927 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
JBrowse link
G Ucp2 uncoupling protein 2 increases expression
multiple interactions
ISO
EXP
Isoproterenol results in increased expression of UCP2 mRNA
Isoproterenol results in increased expression of UCP2 mRNA; Isoproterenol results in increased expression of UCP2 protein
Edaravone inhibits the reaction [Isoproterenol results in increased expression of UCP2 mRNA]; Edaravone inhibits the reaction [Isoproterenol results in increased expression of UCP2 protein]
CTD PMID:16580698 PMID:20003209 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Ucp3 uncoupling protein 3 increases expression
decreases expression
ISO
EXP
Isoproterenol results in increased expression of UCP3 mRNA
Isoproterenol results in decreased expression of UCP3 mRNA
CTD PMID:24286936 NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase increases expression ISO Isoproterenol results in increased expression of UGDH mRNA CTD PMID:21335049 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases expression ISO Isoproterenol results in increased expression of UGT1A2 mRNA CTD PMID:20003209 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ung uracil-DNA glycosylase increases expression ISO Isoproterenol results in increased expression of UNG mRNA CTD PMID:21335049 NCBI chr12:42,485,276...42,494,217
Ensembl chr12:42,485,276...42,494,206
JBrowse link
G Uqcc1 ubiquinol-cytochrome c reductase complex assembly factor 1 decreases expression ISO Isoproterenol results in decreased expression of UQCC1 mRNA CTD PMID:20003209 NCBI chr 3:144,353,276...144,445,810
Ensembl chr 3:144,353,287...144,445,711
JBrowse link
G Usp2 ubiquitin specific peptidase 2 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of USP2 mRNA CTD PMID:30303030 NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
JBrowse link
G Uvrag UV radiation resistance associated increases expression ISO Isoproterenol results in increased expression of UVRAG mRNA CTD PMID:20003209 NCBI chr 1:153,185,356...153,442,200
Ensembl chr 1:153,185,395...153,442,136
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein decreases expression
multiple interactions
EXP Isoproterenol results in decreased expression of VASP protein
natakalim inhibits the reaction [Isoproterenol results in decreased expression of VASP protein]
CTD PMID:27890915 NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 decreases expression ISO Isoproterenol results in decreased expression of VCAM1 mRNA CTD PMID:21335049 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vcan versican increases expression EXP Isoproterenol results in increased expression of VCAN mRNA CTD PMID:20211217 NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression
decreases expression
ISO
EXP
Isoproterenol results in increased expression of VEGFA mRNA
Isoproterenol results in decreased expression of VEGFA mRNA
Isoproterenol results in decreased expression of VEGF protein
Isoproterenol results in decreased expression of VEGF protein; Isoproterenol results in decreased expression of VEGFA mRNA
CTD PMID:10788502 PMID:21335049 PMID:24286936 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vgll3 vestigial-like family member 3 increases expression ISO Isoproterenol results in increased expression of VGLL3 mRNA CTD PMID:20003209 NCBI chr11:3,642,993...3,692,590
Ensembl chr11:3,643,069...3,689,140
JBrowse link
G Vim vimentin decreases expression ISO Isoproterenol results in decreased expression of VIM mRNA CTD PMID:21335049 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Vwf von Willebrand factor increases expression ISO Isoproterenol results in increased expression of VWF mRNA CTD PMID:20003209 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
JBrowse link
G Wdr3 WD repeat domain 3 increases expression ISO Isoproterenol results in increased expression of WDR3 mRNA CTD PMID:20003209 NCBI chr 2:187,505,816...187,528,432
Ensembl chr 2:187,505,816...187,528,432
JBrowse link
G Wfdc1 WAP four-disulfide core domain 1 decreases expression ISO Isoproterenol results in decreased expression of WFDC1 mRNA CTD PMID:20003209 NCBI chr19:47,720,191...47,739,121
Ensembl chr19:47,720,423...47,739,108
JBrowse link
G Xdh xanthine dehydrogenase increases expression
multiple interactions
ISO
EXP
Isoproterenol results in increased expression of XDH mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of XDH mRNA
CTD PMID:20003209 PMID:30303030 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor increases expression ISO Isoproterenol results in increased expression of XPA mRNA CTD PMID:20003209 NCBI chr 5:60,431,673...60,475,726
Ensembl chr 5:60,431,673...60,475,726
JBrowse link
G Ypel2 yippee-like 2 increases expression ISO Isoproterenol results in increased expression of YPEL2 mRNA CTD PMID:20003209 NCBI chr10:71,746,308...71,803,843
Ensembl chr10:71,746,311...71,803,911
JBrowse link
G Ypel3 yippee-like 3 increases expression ISO Isoproterenol results in increased expression of YPEL3 mRNA CTD PMID:20003209 NCBI chr 1:181,384,385...181,387,706
Ensembl chr 1:181,384,357...181,387,705
JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of YWHAG mRNA CTD PMID:30303030 NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827
JBrowse link
G Yy1 YY1 transcription factor increases expression ISO Isoproterenol results in increased expression of YY1 mRNA CTD PMID:20003209 NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747
JBrowse link
G Zbtb11 zinc finger and BTB domain containing 11 increases expression ISO Isoproterenol results in increased expression of ZBTB11 mRNA CTD PMID:20003209 NCBI chr11:44,598,694...44,652,559
Ensembl chr11:44,616,289...44,651,050
JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 increases expression ISO Isoproterenol results in increased expression of ZBTB16 mRNA CTD PMID:20003209 NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
JBrowse link
G Zbtb44 zinc finger and BTB domain containing 44 increases expression ISO Isoproterenol results in increased expression of ZBTB44 mRNA CTD PMID:20003209 NCBI chr 8:29,466,055...29,524,027
Ensembl chr 8:29,466,352...29,518,163
JBrowse link
G Zfand5 zinc finger AN1-type containing 5 multiple interactions EXP [Isoproterenol co-treated with POSTN protein] results in decreased expression of ZFAND5 mRNA CTD PMID:30303030 NCBI chr 1:218,765,735...218,780,391
Ensembl chr 1:218,766,614...218,775,843
JBrowse link
G Zfp207 zinc finger protein 207 increases expression ISO Isoproterenol results in increased expression of ZFP207 mRNA CTD PMID:21335049 NCBI chr10:65,385,807...65,398,086
Ensembl chr10:65,385,740...65,397,386
JBrowse link
G Zfp236 zinc finger protein 236 increases expression ISO Isoproterenol results in increased expression of ZFP236 mRNA CTD PMID:20003209 NCBI chr18:75,976,478...76,072,428
Ensembl chr18:75,978,231...76,073,737
JBrowse link
G Zfp346 zinc finger protein 346 increases expression ISO Isoproterenol results in increased expression of ZFP346 mRNA CTD PMID:20003209 NCBI chr17:9,493,787...9,523,681
Ensembl chr17:9,493,803...9,523,635
JBrowse link
G Zfp428 zinc finger protein 428 decreases expression ISO Isoproterenol results in decreased expression of ZFP428 mRNA CTD PMID:20003209 NCBI chr 1:80,099,520...80,108,875
Ensembl chr 1:80,099,441...80,108,870
JBrowse link
G Zfp451 zinc finger protein 451 increases expression ISO Isoproterenol results in increased expression of ZFP451 mRNA CTD PMID:20003209 NCBI chr 9:35,985,441...36,040,991
Ensembl chr 9:35,985,443...36,040,652
JBrowse link
G Zmym5 zinc finger MYM-type containing 5 increases expression ISO Isoproterenol results in increased expression of ZMYM5 mRNA CTD PMID:20003209 NCBI chr15:30,920,479...30,941,249
Ensembl chr15:30,923,241...30,941,240
JBrowse link
G Zranb3 zinc finger RANBP2-type containing 3 increases expression ISO Isoproterenol results in increased expression of ZRANB3 mRNA CTD PMID:20003209 NCBI chr13:39,440,653...39,595,782
Ensembl chr13:39,440,889...39,595,670
JBrowse link
G Zw10 zw10 kinetochore protein increases expression ISO Isoproterenol results in increased expression of ZW10 mRNA CTD PMID:21335049 NCBI chr 8:49,396,541...49,424,743
Ensembl chr 8:49,396,545...49,421,805
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      application 19627
        pharmaceutical 19468
          drug 19468
            bronchodilator agent 3811
              isoprenaline 1159
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    main group molecular entity 19756
                      s-block molecular entity 19595
                        hydrogen molecular entity 19582
                          hydrides 19095
                            inorganic hydride 18093
                              pnictogen hydride 18082
                                nitrogen hydride 17989
                                  azane 17798
                                    ammonia 17797
                                      organic amino compound 17797
                                        secondary amino compound 6829
                                          isoprenaline 1159
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