Tuba8 (tubulin, alpha 8) - Rat Genome Database

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Gene: Tuba8 (tubulin, alpha 8) Rattus norvegicus
Analyze
Symbol: Tuba8
Name: tubulin, alpha 8
RGD ID: 1566041
Description: Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization; mitotic cell cycle; and spermatid development. Predicted to be located in microtubule cytoskeleton. Predicted to be active in acrosomal vesicle and microtubule. Human ortholog(s) of this gene implicated in thrombocytopenia. Orthologous to human TUBA8 (tubulin alpha 8); PARTICIPATES IN phagocytosis pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: alpha-tubulin 8; LOC500377; similar to Tubulin alpha-8 chain (Alpha-tubulin 8); tubulin alpha-8 chain
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24154,440,045 - 154,456,918 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4154,440,074 - 154,456,917 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4160,705,807 - 160,723,049 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.04156,489,290 - 156,506,534 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.04155,112,778 - 155,130,023 (+)NCBIRnor_WKY
Rnor_6.04153,774,511 - 153,791,223 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4153,774,486 - 153,791,328 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04220,863,728 - 220,880,838 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera4143,280,073 - 143,296,818 (+)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-tribromophenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
all-trans-retinoic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
Benzo[k]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
Cuprizon  (EXP)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
graphite  (EXP)
indometacin  (ISO)
isoprenaline  (ISO)
L-methionine  (ISO)
lead nitrate  (EXP)
lipopolysaccharide  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
PCB138  (ISO)
pentachlorophenol  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
quercetin  (EXP)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
sodium fluoride  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (EXP,ISO)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. A revised nomenclature for the human and rodent alpha-tubulin gene family. Khodiyar VK, etal., Genomics. 2007 May 31;.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:29476059  


Genomics

Comparative Map Data
Tuba8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24154,440,045 - 154,456,918 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4154,440,074 - 154,456,917 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4160,705,807 - 160,723,049 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.04156,489,290 - 156,506,534 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.04155,112,778 - 155,130,023 (+)NCBIRnor_WKY
Rnor_6.04153,774,511 - 153,791,223 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4153,774,486 - 153,791,328 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04220,863,728 - 220,880,838 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera4143,280,073 - 143,296,818 (+)NCBICelera
Cytogenetic Map4q42NCBI
TUBA8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382218,110,809 - 18,131,732 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2218,110,100 - 18,146,683 (+)EnsemblGRCh38hg38GRCh38
GRCh372218,593,575 - 18,614,499 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362216,973,559 - 16,994,498 (+)NCBINCBI36Build 36hg18NCBI36
Build 342216,968,112 - 16,989,052NCBI
Celera222,212,521 - 2,233,563 (+)NCBICelera
Cytogenetic Map22q11.21NCBI
HuRef222,405,998 - 2,426,924 (+)NCBIHuRef
CHM1_12218,593,173 - 18,614,215 (+)NCBICHM1_1
T2T-CHM13v2.02218,782,719 - 18,803,642 (+)NCBIT2T-CHM13v2.0
Tuba8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396121,187,666 - 121,209,304 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6121,187,655 - 121,203,813 (+)EnsemblGRCm39 Ensembl
GRCm386121,210,734 - 121,226,098 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6121,210,696 - 121,226,854 (+)EnsemblGRCm38mm10GRCm38
MGSCv376121,160,788 - 121,176,115 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366121,176,389 - 121,191,716 (+)NCBIMGSCv36mm8
Celera6123,044,550 - 123,060,095 (+)NCBICelera
Cytogenetic Map6F1NCBI
Tuba8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554546,129,612 - 6,148,645 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554546,129,821 - 6,148,645 (+)NCBIChiLan1.0ChiLan1.0
TUBA8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12216,969,150 - 17,012,868 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2216,936,405 - 16,989,730 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0221,541,154 - 1,561,852 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
TUBA8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12745,706,576 - 45,725,679 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2745,675,472 - 45,725,681 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha27958,092 - 977,176 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02746,073,905 - 46,093,210 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2746,045,486 - 46,094,019 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12746,001,476 - 46,020,589 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02745,975,073 - 45,993,987 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.027313,717 - 332,829 (-)NCBIUU_Cfam_GSD_1.0
Tuba8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945109,855,015 - 109,884,560 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049368071,061,529 - 1,084,228 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049368071,061,542 - 1,079,438 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TUBA8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl570,153,922 - 70,179,970 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1570,154,251 - 70,174,001 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2572,507,682 - 72,527,225 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Tuba8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247359,211,152 - 9,230,303 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247359,211,458 - 9,229,909 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tuba8
118 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:26
Count of miRNA genes:26
Interacting mature miRNAs:26
Transcripts:ENSRNOT00000074096
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4109827074154827074Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4109827074154827074Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4109866907167139601Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4110275411168266883Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110870972155870972Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110870972155870972Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4114627026159627026Rat
724535Cm18Cardiac mass QTL 182.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)4118856416163856416Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4119428175157578333Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4123143783168143783Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4124778595169778595Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4125590636170590636Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4126395976167139601Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
1549827Scl46Serum cholesterol level QTL 463.5blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)4132396220177396220Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4132642577167139601Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (CMO:0000132)4135204660180204660Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)4135699135180699135Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4137755016181392681Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4145568712182687754Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4146565735175236377Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4147278504167139601Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4148090542168069246Rat
61446Coreg2Compensatory renal growth QTL 23.5kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)4148423102157580971Rat
1581574Eae20Experimental allergic encephalomyelitis QTL 207.8nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)4153031106158841762Rat

Markers in Region
RH144572  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24154,452,488 - 154,452,695 (+)MAPPERmRatBN7.2
Rnor_6.04153,786,794 - 153,787,000NCBIRnor6.0
Rnor_5.04220,876,409 - 220,876,615UniSTSRnor5.0
Celera4143,292,416 - 143,292,622UniSTS
RH 3.4 Map4995.9UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 19 9 6 3 6 8 11 23 7 8
Low 6 30 18 16 18 23 17 10 11
Below cutoff 2 18 13 12 12 24 16 22

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000074096   ⟹   ENSRNOP00000065108
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4154,440,074 - 154,456,917 (+)Ensembl
Rnor_6.0 Ensembl4153,774,486 - 153,791,328 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094482   ⟹   ENSRNOP00000079773
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4154,446,523 - 154,456,917 (+)Ensembl
RefSeq Acc Id: NM_001024339   ⟹   NP_001019510
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24154,440,130 - 154,456,918 (+)NCBI
Rnor_6.04153,774,511 - 153,791,223 (+)NCBI
Rnor_5.04220,863,728 - 220,880,838 (+)NCBI
Celera4143,280,073 - 143,296,818 (+)RGD
Sequence:
RefSeq Acc Id: XM_017592844   ⟹   XP_017448333
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24154,440,045 - 154,456,918 (+)NCBI
Rnor_6.04153,774,627 - 153,791,223 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039108236   ⟹   XP_038964164
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24154,446,940 - 154,456,918 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001019510 (Get FASTA)   NCBI Sequence Viewer  
  XP_017448333 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964164 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79185 (Get FASTA)   NCBI Sequence Viewer  
  EDM02020 (Get FASTA)   NCBI Sequence Viewer  
  Q6AY56 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001019510   ⟸   NM_001024339
- UniProtKB: Q6AY56 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017448333   ⟸   XM_017592844
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000065108   ⟸   ENSRNOT00000074096
RefSeq Acc Id: XP_038964164   ⟸   XM_039108236
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZN97 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000079773   ⟸   ENSRNOT00000094482
Protein Domains
Tubulin   Tubulin_C

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AY56-F1-model_v2 AlphaFold Q6AY56 1-449 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693362
Promoter ID:EPDNEW_R3886
Type:initiation region
Name:Tuba8_1
Description:tubulin, alpha 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04153,774,500 - 153,774,560EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1566041 AgrOrtholog
BioCyc Gene G2FUF-43185 BioCyc
Ensembl Genes ENSRNOG00000048169 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000065108 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000079773 ENTREZGENE
  ENSRNOP00000079773.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000074096 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000094482 ENTREZGENE
  ENSRNOT00000094482.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.600 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.1330.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.1440 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7131106 IMAGE-MGC_LOAD
InterPro Alpha_tubulin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tub_FtsZ_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tubulin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tubulin/FtsZ-like_C UniProtKB/TrEMBL
  Tubulin/FtsZ_2-layer-sand-dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tubulin/FtsZ_C_sf UniProtKB/Swiss-Prot
  Tubulin/FtsZ_GTPase_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tubulin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tubulin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tubulin_FtsZ_GTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:500377 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94229 IMAGE-MGC_LOAD
NCBI Gene 500377 ENTREZGENE
PANTHER PTHR11588 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Tubulin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tubulin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tuba8 PhenoGen
PRINTS ALPHATUBULIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TUBULIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TUBULIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Tubulin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tubulin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52490 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55307 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZN97 ENTREZGENE, UniProtKB/TrEMBL
  Q6AY56 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-01-09 Tuba8  tubulin, alpha 8  LOC682022  similar to Tubulin alpha-8 chain (Alpha-tubulin 8)  Data Merged 1643240 APPROVED
2007-05-17 Tuba8  tubulin, alpha 8  LOC500377  similar to Tubulin alpha-8 chain (Alpha-tubulin 8)  Symbol and Name updated 1624988 APPROVED
2006-11-19 LOC682022  similar to Tubulin alpha-8 chain (Alpha-tubulin 8)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-02-09 LOC500377  similar to Tubulin alpha-8 chain (Alpha-tubulin 8)      Symbol and Name status set to provisional 70820 PROVISIONAL