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Gene: Tuba8 (tubulin, alpha 8) Rattus norvegicus
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Symbol: Tuba8
Name: tubulin, alpha 8
Description: Predicted to have GTP binding activity. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to localize to the cytoplasm and microtubule. Human ortholog(s) of this gene implicated in Fanconi syndrome and complex cortical dysplasia with other brain malformations. Orthologous to human EHHADH (enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase) and TUBA8 (tubulin alpha 8); PARTICIPATES IN phagocytosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: alpha-tubulin 8; LOC500377; similar to Tubulin alpha-8 chain (Alpha-tubulin 8); tubulin alpha-8 chain
Orthologs:
Homo sapiens (human) : TUBA8 (tubulin alpha 8)  HGNC  Alliance
Mus musculus (house mouse) : Tuba8 (tubulin, alpha 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tuba8 (tubulin alpha 8)
Pan paniscus (bonobo/pygmy chimpanzee) : TUBA8 (tubulin alpha 8)
Canis lupus familiaris (dog) : TUBA8 (tubulin alpha 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tuba8 (tubulin alpha 8)
Sus scrofa (pig) : TUBA8 (tubulin alpha 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04153,774,511 - 153,791,223 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04220,863,728 - 220,880,838 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera4143,280,073 - 143,296,818 (+)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tuba8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1566041
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.