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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620411
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mb
Name: myoglobin
Acc ID: CHEBI:64317
Term: isoprenaline
Definition: A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Chemical ID: MESH:D007545
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mbincreases expressionEXP 6480464CTDIsoproterenol results in increased expression of MB proteinPMID:32627257 PMID:533011
Mbincreases secretionEXP 6480464CTDIsoproterenol results in increased secretion of MB proteinPMID:19628585
Mbmultiple interactionsEXP 6480464CTDsinapinic acid inhibits the reaction [Isoproterenol results in increased expression of MB protein]PMID:32627257
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