Cnksr3 (Cnksr family member 3) - Rat Genome Database

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Gene: Cnksr3 (Cnksr family member 3) Rattus norvegicus
Analyze
Symbol: Cnksr3
Name: Cnksr family member 3
RGD ID: 1307544
Description: Predicted to be involved in negative regulation of ERK1 and ERK2 cascade; negative regulation of peptidyl-serine phosphorylation; and positive regulation of sodium ion transport. Predicted to be located in apical plasma membrane and cytoplasm. Orthologous to human CNKSR3 (CNKSR family member 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CNK homolog protein 3; CNK3; connector enhancer of kinase suppressor of ras 3; connector enhancer of KSR 3; LOC308113; Magi1; maguin-like protein; membrane associated guanylate kinase interacting protein-like 1; membrane-associated guanylate kinase-interacting protein-like 1; parturition-related protein 4; Prp4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8145,904,581 - 45,996,921 (-)NCBIGRCr8
mRatBN7.2143,499,273 - 43,591,630 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl143,499,487 - 43,591,635 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx144,040,536 - 44,133,137 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0150,027,769 - 50,120,372 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0144,116,025 - 44,208,636 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0143,789,797 - 43,884,267 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl143,789,791 - 43,884,267 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0145,119,654 - 45,213,960 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4137,865,904 - 37,958,862 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1137,868,848 - 37,961,807 (-)NCBI
Celera139,135,338 - 39,227,832 (-)NCBICelera
Cytogenetic Map1q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aldrin  (ISO)
all-trans-retinoic acid  (EXP,ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP)
caffeine  (ISO)
carbamazepine  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
DDT  (EXP)
dexamethasone  (ISO)
dibutyl phthalate  (EXP,ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
folic acid  (ISO)
folpet  (ISO)
formaldehyde  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
hydrogen cyanide  (ISO)
hydrogen peroxide  (ISO)
isoprenaline  (ISO)
ketamine  (EXP)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
melphalan  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
pentanal  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
potassium cyanide  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
temozolomide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14596909   PMID:19567370   PMID:22851176  


Genomics

Comparative Map Data
Cnksr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8145,904,581 - 45,996,921 (-)NCBIGRCr8
mRatBN7.2143,499,273 - 43,591,630 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl143,499,487 - 43,591,635 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx144,040,536 - 44,133,137 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0150,027,769 - 50,120,372 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0144,116,025 - 44,208,636 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0143,789,797 - 43,884,267 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl143,789,791 - 43,884,267 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0145,119,654 - 45,213,960 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4137,865,904 - 37,958,862 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1137,868,848 - 37,961,807 (-)NCBI
Celera139,135,338 - 39,227,832 (-)NCBICelera
Cytogenetic Map1q11NCBI
CNKSR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386154,387,515 - 154,510,685 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6154,387,515 - 154,510,685 (-)EnsemblGRCh38hg38GRCh38
GRCh376154,708,649 - 154,831,819 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366154,768,125 - 154,873,445 (-)NCBINCBI36Build 36hg18NCBI36
Build 346154,818,546 - 154,923,906NCBI
Celera6155,460,772 - 155,566,082 (-)NCBICelera
Cytogenetic Map6q25.2NCBI
HuRef6152,289,215 - 152,394,549 (-)NCBIHuRef
CHM1_16154,989,508 - 155,094,800 (-)NCBICHM1_1
T2T-CHM13v2.06155,589,037 - 155,712,112 (-)NCBIT2T-CHM13v2.0
Cnksr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39107,069,061 - 7,162,237 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl107,069,063 - 7,162,237 (-)EnsemblGRCm39 Ensembl
GRCm38107,119,061 - 7,212,237 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl107,119,063 - 7,212,237 (-)EnsemblGRCm38mm10GRCm38
MGSCv37103,134,304 - 3,227,479 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36103,134,304 - 3,227,479 (+)NCBIMGSCv36mm8
Celera107,081,303 - 7,175,417 (-)NCBICelera
Cytogenetic Map10A1NCBI
cM Map101.85NCBI
Cnksr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554397,524,333 - 7,616,447 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554397,524,401 - 7,616,447 (+)NCBIChiLan1.0ChiLan1.0
CNKSR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25174,428,046 - 174,534,938 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16172,319,737 - 172,425,198 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06152,221,458 - 152,326,885 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16156,666,986 - 158,292,640 (-)NCBIpanpan1.1PanPan1.1panPan2
CNKSR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1144,280,132 - 44,361,138 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl144,070,004 - 44,363,107 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha145,116,969 - 45,205,320 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0144,462,865 - 44,552,077 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl144,253,530 - 44,552,166 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1144,330,159 - 44,418,557 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0144,202,964 - 44,291,122 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0144,758,957 - 44,847,009 (-)NCBIUU_Cfam_GSD_1.0
Cnksr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946139,541,292 - 139,628,404 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364896,792,048 - 6,880,445 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364896,792,925 - 6,880,300 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNKSR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl112,297,676 - 12,396,688 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1112,297,740 - 12,396,946 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2114,301,232 - 14,451,489 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CNKSR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11381,945,080 - 82,050,304 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1381,943,423 - 82,050,175 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604054,347,357 - 54,454,077 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cnksr3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247853,805,389 - 3,902,216 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247853,805,829 - 3,905,554 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cnksr3
528 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:112
Count of miRNA genes:89
Interacting mature miRNAs:91
Transcripts:ENSRNOT00000024418
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1439328949393289Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)1985600154856001Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)11183518156835181Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)11543162149361612Rat
5684999Bss102Bone structure and strength QTL 1025.50.00000072tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)11543162149361612Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11620621049268520Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)11933357156983283Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)12076315844095856Rat
724520Bp145Blood pressure QTL 1452.10.0024arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12078482865784828Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12234064749361612Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)12234064749361612Rat
1357400Bw62Body weight QTL624.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)12234064767340647Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)12887978078430678Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)13344984878449848Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)13344984878449848Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13483685879836858Rat
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13523959878430678Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13523959878430678Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat

Markers in Region
BE115327  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2143,574,664 - 43,574,824 (+)MAPPERmRatBN7.2
Rnor_6.0143,866,610 - 43,866,769NCBIRnor6.0
Rnor_5.0145,196,473 - 45,196,632UniSTSRnor5.0
RGSC_v3.4137,941,557 - 37,941,716UniSTSRGSC3.4
Celera139,211,035 - 39,211,194UniSTS
RH 3.4 Map1471.21UniSTS
Cytogenetic Map1p11UniSTS
RH134723  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2143,499,570 - 43,499,788 (+)MAPPERmRatBN7.2
Rnor_6.0143,791,347 - 43,791,564NCBIRnor6.0
Rnor_5.0145,121,204 - 45,121,421UniSTSRnor5.0
RGSC_v3.4137,866,202 - 37,866,419UniSTSRGSC3.4
Celera139,135,636 - 39,135,853UniSTS
Cytogenetic Map1p11UniSTS
AU048431  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2143,530,653 - 43,530,794 (+)MAPPERmRatBN7.2
Rnor_6.0143,822,428 - 43,822,578NCBIRnor6.0
Rnor_5.0145,151,851 - 45,152,001UniSTSRnor5.0
RGSC_v3.4137,897,688 - 37,897,828UniSTSRGSC3.4
Celera139,167,209 - 39,167,349UniSTS
Cytogenetic Map1p11UniSTS
ha1770  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera139,157,006 - 39,158,178UniSTS
Celera695,187,459 - 95,187,776UniSTS
Cytogenetic Map1p11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 12 8 2 13 2 16 25 31 7
Low 3 31 49 39 6 39 8 11 58 10 10 4 8
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000024418   ⟹   ENSRNOP00000024418
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,789,791 - 43,884,267 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000082931   ⟹   ENSRNOP00000070619
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl143,499,487 - 43,591,635 (-)Ensembl
Rnor_6.0 Ensembl143,792,199 - 43,831,932 (-)Ensembl
RefSeq Acc Id: NM_001012061   ⟹   NP_001012061
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8145,904,581 - 45,996,921 (-)NCBI
mRatBN7.2143,499,273 - 43,591,630 (-)NCBI
Rnor_6.0143,791,049 - 43,884,267 (-)NCBI
Rnor_5.0145,119,654 - 45,213,960 (-)NCBI
RGSC_v3.4137,865,904 - 37,958,862 (-)RGD
Celera139,135,338 - 39,227,832 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001012061 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAQ92305 (Get FASTA)   NCBI Sequence Viewer  
  AAR01114 (Get FASTA)   NCBI Sequence Viewer  
  EDL92829 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000070619
  ENSRNOP00000070619.2
GenBank Protein Q5SGD7 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001012061   ⟸   NM_001012061
- UniProtKB: Q6VPP2 (UniProtKB/Swiss-Prot),   Q5SGD7 (UniProtKB/Swiss-Prot),   A6KIP9 (UniProtKB/TrEMBL),   A0A0G2JYE3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000070619   ⟸   ENSRNOT00000082931
RefSeq Acc Id: ENSRNOP00000024418   ⟸   ENSRNOT00000024418
Protein Domains
CRIC   DUF1170   PDZ   SAM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5SGD7-F1-model_v2 AlphaFold Q5SGD7 1-555 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689596
Promoter ID:EPDNEW_R121
Type:multiple initiation site
Name:Cnksr3_1
Description:Cnksr family member 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0143,884,272 - 43,884,332EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307544 AgrOrtholog
BioCyc Gene G2FUF-61676 BioCyc
Ensembl Genes ENSRNOG00000018052 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000082931 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000082931.2 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.150.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.42.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CNKSR2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CRIC_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:308113 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 308113 ENTREZGENE
PANTHER CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CRIC_ras_sig UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DUF1170 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cnksr3 PhenoGen
PROSITE CRIC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018052 RatGTEx
SMART PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47769 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50156 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JYE3 ENTREZGENE, UniProtKB/TrEMBL
  A6KIP9 ENTREZGENE, UniProtKB/TrEMBL
  CNKR3_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6VPP2 ENTREZGENE
UniProt Secondary Q6VPP2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Cnksr3  Cnksr family member 3  Magi1  membrane associated guanylate kinase interacting protein-like 1  Symbol and Name updated 1299863 APPROVED
2005-12-06 Magi1  membrane associated guanylate kinase interacting protein-like 1  Magi1_predicted  membrane associated guanylate kinase interacting protein-like 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Magi1_predicted  membrane associated guanylate kinase interacting protein-like 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED