Myrip (myosin VIIA and Rab interacting protein) - Rat Genome Database

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Gene: Myrip (myosin VIIA and Rab interacting protein) Rattus norvegicus
Analyze
Symbol: Myrip
Name: myosin VIIA and Rab interacting protein
RGD ID: 727731
Description: Enables protein kinase A binding activity. Involved in positive regulation of insulin secretion. Located in apical plasma membrane; perinuclear region of cytoplasm; and secretory granule. Orthologous to human MYRIP (myosin VIIA and Rab interacting protein); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: exophilin-8; myosin-VIIa- and Rab-interacting protein; rab effector MyRIP; slaC2-c; Slac2c; slp homolog lacking C2 domains c; synaptotagmin-like protein lacking C2 domains C
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28120,017,843 - 120,184,821 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl8120,017,524 - 120,183,833 (+)Ensembl
Rnor_6.08128,972,307 - 129,139,257 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8128,972,311 - 129,139,251 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08128,171,783 - 128,337,841 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48125,317,671 - 125,478,667 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18125,337,407 - 125,492,971 (+)NCBI
Celera8119,163,194 - 119,324,938 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function
actin binding  (IBA,IEA,ISO)
metal ion binding  (IEA)
myosin binding  (IBA,IEA,ISO)
protein binding  (IPI,ISO)
protein kinase A binding  (IDA,IEA,ISO)
small GTPase binding  (IEA,ISO)

References

Additional References at PubMed
PMID:12221080  


Genomics

Comparative Map Data
Myrip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28120,017,843 - 120,184,821 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl8120,017,524 - 120,183,833 (+)Ensembl
Rnor_6.08128,972,307 - 129,139,257 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8128,972,311 - 129,139,251 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08128,171,783 - 128,337,841 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48125,317,671 - 125,478,667 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18125,337,407 - 125,492,971 (+)NCBI
Celera8119,163,194 - 119,324,938 (+)NCBICelera
Cytogenetic Map8q32NCBI
MYRIP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38339,808,914 - 40,260,321 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl339,808,914 - 40,260,321 (+)EnsemblGRCh38hg38GRCh38
GRCh37339,850,405 - 40,301,812 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36339,826,307 - 40,276,816 (+)NCBINCBI36hg18NCBI36
Build 34339,826,306 - 40,276,808NCBI
Celera339,793,218 - 40,244,467 (+)NCBI
Cytogenetic Map3p22.1NCBI
HuRef339,894,694 - 40,345,886 (+)NCBIHuRef
CHM1_1339,802,159 - 40,251,713 (+)NCBICHM1_1
Myrip
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399120,132,996 - 120,305,167 (+)NCBIGRCm39mm39
GRCm39 Ensembl9120,130,579 - 120,303,907 (+)Ensembl
GRCm389120,303,520 - 120,476,101 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9120,301,513 - 120,474,841 (+)EnsemblGRCm38mm10GRCm38
MGSCv379120,213,191 - 120,383,952 (+)NCBIGRCm37mm9NCBIm37
MGSCv369120,152,771 - 120,323,532 (+)NCBImm8
Celera9120,765,412 - 120,944,453 (+)NCBICelera
Cytogenetic Map9F4NCBI
Myrip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542029,540,027 - 29,696,504 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542029,542,479 - 29,697,646 (-)NCBIChiLan1.0ChiLan1.0
MYRIP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1339,991,586 - 40,435,763 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl340,079,777 - 40,433,613 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0339,715,890 - 40,163,826 (+)NCBIMhudiblu_PPA_v0panPan3
MYRIP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1239,448,564 - 9,765,328 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl239,448,559 - 9,763,182 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha239,425,279 - 9,798,884 (+)NCBI
ROS_Cfam_1.0239,674,928 - 10,051,701 (+)NCBI
ROS_Cfam_1.0 Ensembl239,674,852 - 10,051,368 (+)Ensembl
UMICH_Zoey_3.1239,487,819 - 9,861,978 (+)NCBI
UNSW_CanFamBas_1.0239,629,847 - 9,999,590 (+)NCBI
UU_Cfam_GSD_1.0239,625,718 - 9,987,209 (+)NCBI
LOC101956703
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118195,783,381 - 196,114,170 (+)NCBI
SpeTri2.0NW_00493647328,921,837 - 29,252,737 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYRIP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1324,347,660 - 24,556,735 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11324,347,574 - 24,556,743 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21326,806,466 - 26,855,152 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103227432
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1221,369,820 - 1,765,121 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl221,370,001 - 1,765,311 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041165,438,597 - 165,844,373 (-)NCBIVero_WHO_p1.0
Myrip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473078,388,192 - 78,582,051 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
BF416406  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28120,167,549 - 120,167,780 (+)MAPPERmRatBN7.2
Rnor_6.08129,121,990 - 129,122,220NCBIRnor6.0
Rnor_5.08128,320,277 - 128,320,507UniSTSRnor5.0
RGSC_v3.48125,462,150 - 125,462,380UniSTSRGSC3.4
Celera8119,309,656 - 119,309,886UniSTS
RH 3.4 Map81284.4UniSTS
Cytogenetic Map8q32UniSTS
BF416438  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28120,162,186 - 120,162,279 (+)MAPPERmRatBN7.2
Rnor_6.08129,116,917 - 129,117,009NCBIRnor6.0
Rnor_5.08128,315,204 - 128,315,296UniSTSRnor5.0
RGSC_v3.48125,456,680 - 125,456,772UniSTSRGSC3.4
Celera8119,304,878 - 119,304,970UniSTS
RH 3.4 Map81284.4UniSTS
Cytogenetic Map8q32UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8100149864120994388Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:107
Count of miRNA genes:95
Interacting mature miRNAs:99
Transcripts:ENSRNOT00000025460
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 1 2 40 9 11
Low 2 40 30 20 6 20 8 11 30 35 32 8
Below cutoff 2 25 21 13 21 4

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_182844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AY331984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000025460   ⟹   ENSRNOP00000025460
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8120,017,524 - 120,183,833 (+)Ensembl
Rnor_6.0 Ensembl8128,972,311 - 129,139,251 (+)Ensembl
RefSeq Acc Id: NM_182844   ⟹   NP_878264
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28120,049,401 - 120,182,847 (+)NCBI
Rnor_6.08129,003,687 - 129,137,284 (+)NCBI
Rnor_5.08128,171,783 - 128,337,841 (+)NCBI
RGSC_v3.48125,317,671 - 125,478,667 (+)RGD
Celera8119,163,194 - 119,324,938 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244110   ⟹   XP_006244172
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28120,017,845 - 120,184,821 (+)NCBI
Rnor_6.08128,972,307 - 129,139,257 (+)NCBI
Rnor_5.08128,171,783 - 128,337,841 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008766686   ⟹   XP_008764908
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28120,127,814 - 120,184,821 (+)NCBI
Rnor_6.08129,082,621 - 129,139,257 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008766687   ⟹   XP_008764909
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28120,126,947 - 120,184,821 (+)NCBI
Rnor_6.08129,081,773 - 129,139,257 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039081681   ⟹   XP_038937609
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28120,017,845 - 120,184,821 (+)NCBI
RefSeq Acc Id: XM_039081682   ⟹   XP_038937610
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28120,017,843 - 120,184,821 (+)NCBI
RefSeq Acc Id: XM_039081683   ⟹   XP_038937611
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28120,018,178 - 120,184,821 (+)NCBI
RefSeq Acc Id: XM_039081684   ⟹   XP_038937612
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28120,018,178 - 120,184,821 (+)NCBI
RefSeq Acc Id: XM_039081685   ⟹   XP_038937613
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28120,018,031 - 120,184,821 (+)NCBI
RefSeq Acc Id: XM_039081686   ⟹   XP_038937614
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28120,073,710 - 120,184,821 (+)NCBI
RefSeq Acc Id: XM_039081687   ⟹   XP_038937615
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28120,017,845 - 120,184,821 (+)NCBI
RefSeq Acc Id: XM_039081688   ⟹   XP_038937616
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28120,017,845 - 120,184,821 (+)NCBI
RefSeq Acc Id: XM_039081689   ⟹   XP_038937617
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28120,127,814 - 120,184,821 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_878264   ⟸   NM_182844
- UniProtKB: Q7TNY7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006244172   ⟸   XM_006244110
- Peptide Label: isoform X2
- UniProtKB: D3ZTL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008764909   ⟸   XM_008766687
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_008764908   ⟸   XM_008766686
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: ENSRNOP00000025460   ⟸   ENSRNOT00000025460
RefSeq Acc Id: XP_038937610   ⟸   XM_039081682
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038937609   ⟸   XM_039081681
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038937615   ⟸   XM_039081687
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038937616   ⟸   XM_039081688
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038937613   ⟸   XM_039081685
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038937611   ⟸   XM_039081683
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038937612   ⟸   XM_039081684
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038937614   ⟸   XM_039081686
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038937617   ⟸   XM_039081689
- Peptide Label: isoform X6
Protein Domains
RabBD

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
8 128288802 128288803 T A snv WAG/Rij (KNAW), MR/N (KNAW)
8 128296541 128296542 G A snv COP/CrCrl (MCW & UW), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), SBH/Ygl (MCW), SBN/Ygl (MCW), SR/JrHsd (MCW), SS/JrHsdMcwi (MCW), WN/N (KNAW), LH/MavRrrc (KNAW), LL/MavRrrc (KNAW), LN/MavRrrc (KNAW), MHS/Gib (KNAW), SR/JrHsd (KNAW), SS/Jr (KNAW), SS/JrHsdMcwi (KNAW), ACI/N (KNAW), ACI/EurMcwi (KNAW), BBDP/WorN (KNAW), DA/BklArbNsi (KNAW), F344/NRrrc (SOLiD) (KNAW), F344/NCrl (KNAW), ZF (KyushuU), FHH/EurMcwi (KNAW), FHL/EurMcwi (KNAW), LEW/Crl (KNAW), LEW/NCrl (KNAW), MNS/Gib (KNAW), SBH/Ygl (KNAW), SBN/Ygl (KNAW), F344/NRrrc (Illumina) (KNAW), SDLEF7/Barth (UDEL), LE/OrlBarth (UDEL), Crl:SD (UDEL), IS/Kyo (KyushuU), BUF/MNa (KyushuU), NIG-III/Hok (KyushuU), F344/DuCrlCrlj (KyushuU), HTX/Kyo (KyushuU), F344/NSlc (KyushuU), RCS/Kyo (KyushuU), IS-Tlk/Kyo (KyushuU), F344/Stm (KyushuU), HWY/Slc (KyushuU), F344/Jcl (KyushuU), BDIX/NemOda (KyushuU), BDIX.Cg-Tal/NemOda (KyushuU), KFRS3B/Kyo (KyushuU), ACI/EurMcwi (MCW), ZFDM (KyushuU), F344/NHsd (KNAW)


Assembly: mRatBN7.2

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
8 120135770 120135771 T A snv MR/N (2020), WAG/RijCrl (2020)
8 120143511 120143512 G A snv DA/OlaHsd (2019), F344/DuCrl (2019), F344/NCrl (2019), F344/N (2020), F344/Stm (2019), FHH/EurMcwi (2019), WN/N (2020), LEW/Crl (2019), LEXF11/Stm (2020), LEXF2B/Stm (2019), LH/MavRrrcAek (2020), LL/MavRrrcAek (2020), LN/MavRrrcAek (2020), MWF/Hsd (2019), PVG/Seac (2019), SR/JrHsd (2020), SS/JrHsdMcwi (2019), ACI/N (2020), ACI/EurMcwi (2019), FXLE18/Stm (2020)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:727731 AgrOrtholog
BioCyc Gene G2FUF-28743 BioCyc
Ensembl Genes ENSRNOG00000018797 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000025460 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000025460 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FYVE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myrip/Melanophilin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rab_BD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:360034 UniProtKB/Swiss-Prot
NCBI Gene 360034 ENTREZGENE
Pfam FYVE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rab_eff_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Myrip PhenoGen
PROSITE RABBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57903 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3ZTL2 ENTREZGENE, UniProtKB/TrEMBL
  MYRIP_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Myrip  myosin VIIA and Rab interacting protein      Symbol and Name status set to approved 1299863 APPROVED