Pirb (paired Ig-like receptor B) - Rat Genome Database

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Gene: Pirb (paired Ig-like receptor B) Rattus norvegicus
Analyze
Symbol: Pirb
Name: paired Ig-like receptor B
RGD ID: 1589827
Description: Predicted to enable amyloid-beta binding activity; inhibitory MHC class I receptor activity; and protein homodimerization activity. Predicted to be involved in several processes, including negative regulation of osteoclast differentiation; regulation of protein metabolic process; and regulation of synaptic plasticity. Predicted to act upstream of or within B cell homeostasis; B cell mediated immunity; and myeloid dendritic cell differentiation. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to several human genes including LILRB3 (leukocyte immunoglobulin like receptor B3); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: leukocyte immunoglobulin-like receptor subfamily B member 3-like; Leukocyte immunoglobulin-like receptor subfamily B member 3A; Leukocyte immunoglobulin-like receptor subfamily B member 3B; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3A; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3B; Lilrb3a; Lilrb3b; Lilrb3l; LOC690955; Pir-A1; similar to paired-Ig-like receptor B
RGD Orthologs
Human
Mouse
Bonobo
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8174,414,556 - 74,433,015 (+)NCBIGRCr8
mRatBN7.2165,499,195 - 65,506,666 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl165,499,195 - 65,506,666 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0164,005,797 - 64,013,268 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl164,074,231 - 64,081,438 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl163,759,638 - 64,013,289 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0162,998,083 - 63,005,523 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0163,066,408 - 63,073,848 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4163,812,260 - 63,819,599 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera163,224,301 - 63,231,772 (+)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Human LilrB2 is a ß-amyloid receptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's model. Kim T, etal., Science. 2013 Sep 20;341(6152):1399-404. doi: 10.1126/science.1242077.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12021780   PMID:12947022   PMID:15057822   PMID:16735691   PMID:18802077  


Genomics

Comparative Map Data
Pirb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8174,414,556 - 74,433,015 (+)NCBIGRCr8
mRatBN7.2165,499,195 - 65,506,666 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl165,499,195 - 65,506,666 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0164,005,797 - 64,013,268 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl164,074,231 - 64,081,438 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl163,759,638 - 64,013,289 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0162,998,083 - 63,005,523 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0163,066,408 - 63,073,848 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4163,812,260 - 63,819,599 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera163,224,301 - 63,231,772 (+)NCBICelera
Cytogenetic Map1q12NCBI
LILRB3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381954,216,278 - 54,223,007 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1954,216,278 - 54,223,506 (-)EnsemblGRCh38hg38GRCh38
GRCh371954,720,147 - 54,746,631 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361959,411,959 - 59,418,771 (-)NCBINCBI36Build 36hg18NCBI36
Build 341959,412,548 - 59,438,461NCBI
Celera1951,761,822 - 51,864,872 (-)NCBICelera
Cytogenetic Map19q13.42NCBI
HuRef1951,035,967 - 51,040,525 (-)NCBIHuRef
CHM1_11954,721,297 - 54,728,106 (-)NCBICHM1_1
T2T-CHM13v2.01957,296,666 - 57,303,395 (-)NCBIT2T-CHM13v2.0
Pirb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3973,715,504 - 3,723,381 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl73,714,408 - 3,723,390 (-)EnsemblGRCm39 Ensembl
GRCm3873,712,505 - 3,720,382 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl73,711,409 - 3,720,391 (-)EnsemblGRCm38mm10GRCm38
MGSCv3773,664,107 - 3,671,984 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3673,315,619 - 3,323,469 (-)NCBIMGSCv36mm8
Celera73,626,073 - 3,649,918 (-)NCBICelera
Cytogenetic Map7A1NCBI
cM Map72.14NCBI
LOC100991256
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22060,219,542 - 60,227,293 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11962,142,235 - 62,148,611 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01951,148,567 - 51,154,764 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11959,989,855 - 60,015,767 (-)NCBIpanpan1.1PanPan1.1panPan2
LOC611446
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11102,955,916 - 102,978,669 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1103,033,688 - 103,040,386 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01103,617,135 - 103,623,833 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11103,259,746 - 103,266,445 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01103,015,519 - 103,022,218 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01103,730,424 - 103,737,122 (+)NCBIUU_Cfam_GSD_1.0

Variants

.
Variants in Pirb
483 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
724520Bp145Blood pressure QTL 1452.10.0024arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12078482865784828Rat
1357400Bw62Body weight QTL624.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)12234064767340647Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)12887978078430678Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)13344984878449848Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)13344984878449848Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13483685879836858Rat
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13523959878430678Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13523959878430678Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14580314078430678Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14936146582174945Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)15389511782174945Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15389511782174945Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat

Markers in Region
RH132676  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2165,506,461 - 65,506,654 (+)MAPPERmRatBN7.2
Rnor_6.0164,081,364 - 64,081,556NCBIRnor6.0
Rnor_6.0164,013,064 - 64,013,256NCBIRnor6.0
Rnor_5.0163,073,644 - 63,073,836UniSTSRnor5.0
Rnor_5.0163,005,319 - 63,005,511UniSTSRnor5.0
RGSC_v3.4163,819,393 - 63,819,585UniSTSRGSC3.4
Celera163,231,568 - 63,231,760UniSTS
RH 3.4 Map5804.4UniSTS
Cytogenetic Map1q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 1 11 5 9
Below cutoff 2 17 43 29 8 29 5 8 7 14 18 2 5

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001313924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_001076302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003748713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006228061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006228062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006228063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006228064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006228067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006228068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006228069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006228070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010057604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010057608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010057612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC103574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF111715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO555744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM040423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ189462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ189463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ208975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000077327   ⟹   ENSRNOP00000071172
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl165,499,195 - 65,506,666 (+)Ensembl
Rnor_6.0 Ensembl164,074,231 - 64,081,438 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000087669   ⟹   ENSRNOP00000075744
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl165,499,329 - 65,506,666 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000087957   ⟹   ENSRNOP00000073630
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl165,499,195 - 65,506,666 (+)Ensembl
RefSeq Acc Id: NM_001313924   ⟹   NP_001300853
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8174,414,556 - 74,422,027 (+)NCBI
mRatBN7.2165,499,195 - 65,506,666 (+)NCBI
RefSeq Acc Id: XM_001076302   ⟹   XP_001076302
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8174,414,586 - 74,433,015 (+)NCBI
mRatBN7.2165,499,231 - 65,506,666 (+)NCBI
Rnor_6.0164,074,104 - 64,081,568 (+)NCBI
Rnor_5.0163,066,408 - 63,073,848 (+)NCBI
RGSC_v3.4163,812,260 - 63,819,599 (+)RGD
Sequence:
RefSeq Acc Id: XM_006228067   ⟹   XP_006228129
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8174,414,586 - 74,433,015 (+)NCBI
mRatBN7.2165,499,232 - 65,506,666 (+)NCBI
Rnor_6.0164,074,104 - 64,081,568 (+)NCBI
Rnor_5.0163,066,408 - 63,073,848 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006228068   ⟹   XP_006228130
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8174,414,580 - 74,433,015 (+)NCBI
mRatBN7.2165,499,215 - 65,506,666 (+)NCBI
Rnor_6.0164,074,103 - 64,081,568 (+)NCBI
Rnor_5.0163,066,408 - 63,073,848 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006228069   ⟹   XP_006228131
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8174,414,593 - 74,433,015 (+)NCBI
mRatBN7.2165,499,233 - 65,506,666 (+)NCBI
Rnor_6.0164,074,103 - 64,081,568 (+)NCBI
Rnor_5.0163,066,408 - 63,073,848 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006228070   ⟹   XP_006228132
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8174,414,594 - 74,433,015 (+)NCBI
mRatBN7.2165,499,234 - 65,506,666 (+)NCBI
Rnor_6.0164,074,102 - 64,081,568 (+)NCBI
Rnor_5.0163,066,408 - 63,073,848 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063273797   ⟹   XP_063129867
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8174,414,579 - 74,433,015 (+)NCBI
RefSeq Acc Id: XM_063273801   ⟹   XP_063129871
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8174,414,595 - 74,433,015 (+)NCBI
RefSeq Acc Id: XR_010057604
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8174,414,586 - 74,433,015 (+)NCBI
RefSeq Acc Id: XR_010057608
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8174,414,586 - 74,433,015 (+)NCBI
RefSeq Acc Id: XR_010057612
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8174,414,586 - 74,433,015 (+)NCBI
RefSeq Acc Id: XP_001076302   ⟸   XM_001076302
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006228130   ⟸   XM_006228068
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006228129   ⟸   XM_006228067
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006228132   ⟸   XM_006228070
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006228131   ⟸   XM_006228069
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSRNOP00000071172   ⟸   ENSRNOT00000077327
RefSeq Acc Id: ENSRNOP00000073630   ⟸   ENSRNOT00000087957
RefSeq Acc Id: ENSRNOP00000075744   ⟸   ENSRNOT00000087669
RefSeq Acc Id: NP_001300853   ⟸   NM_001313924
- Peptide Label: precursor
- UniProtKB: C0HJX3 (UniProtKB/Swiss-Prot),   C0HJX2 (UniProtKB/Swiss-Prot),   A0A0G2K607 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_063129867   ⟸   XM_063273797
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063129871   ⟸   XM_063273801
- Peptide Label: isoform X7
Protein Domains
Ig-like   Ig-like C2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-C0HJX2-F1-model_v2 AlphaFold C0HJX2 1-744 view protein structure
AF-C0HJX3-F1-model_v2 AlphaFold C0HJX3 1-744 view protein structure
AF-A0A0G2KBC9-F1-model_v2 AlphaFold A0A0G2KBC9 1-761 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1589827 AgrOrtholog
Ensembl Genes ENSRNOG00000053260 Ensembl
  ENSRNOG00000058422 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00060029830 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000077327 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000077327.2 UniProtKB/Swiss-Prot
  ENSRNOT00000087669.2 UniProtKB/TrEMBL
  ENSRNOT00000087957.2 UniProtKB/TrEMBL
  ENSRNOT00060051858 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:683463 UniProtKB/Swiss-Prot
NCBI Gene Pirb ENTREZGENE
PANTHER LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY B MEMBER 3-RELATED UniProtKB/TrEMBL
  LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY B MEMBER 4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC CLASS I NK CELL RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ig_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00047 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pirb PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000053260 RatGTEx
  ENSRNOG00000058422 RatGTEx
  ENSRNOG00060029830 RatGTEx
SMART IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K607 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2KBC9 ENTREZGENE
  A0A8L2RBI0_RAT UniProtKB/TrEMBL
  C0HJX2 ENTREZGENE
  C0HJX3 ENTREZGENE
  D3ZVL0_RAT UniProtKB/TrEMBL
  LRB3A_RAT UniProtKB/Swiss-Prot
  LRB3B_RAT UniProtKB/Swiss-Prot
  LRB3L_RAT UniProtKB/Swiss-Prot
UniProt Secondary A2JHX5 UniProtKB/Swiss-Prot
  A2JHX6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-03-07 Pirb  paired Ig-like receptor B  Lilrb3a  leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3A  Data merged from RGD:1586827 737654 PROVISIONAL
2016-01-26 Pirb  paired Ig-like receptor B  Lilrb3b  leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3B  Name and Symbol changed 629549 APPROVED
2015-09-23 Lilrb3a  leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3A  LOC683463  similar to paired-Ig-like receptor B  Name and Symbol changed 629549 APPROVED
2015-09-23 Lilrb3b  leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3B  LOC690955  similar to paired-Ig-like receptor B  Name and Symbol changed 629549 APPROVED
2006-11-20 LOC690955  similar to paired-Ig-like receptor B      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC683463  similar to paired-Ig-like receptor B      Symbol and Name status set to provisional 70820 PROVISIONAL