Gene: Man1a1 (mannosidase, alpha, class 1A, member 1) Rattus norvegicus
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Symbol: Man1a1
Name: mannosidase, alpha, class 1A, member 1
Description: ENCODES a protein that exhibits calcium ion binding (inferred); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; N-linked glycan biosynthetic pathway; ASSOCIATED WITH intellectual disability (ortholog); Language Development Disorders (ortholog); microcephaly (ortholog); FOUND IN cytosol (ortholog); endoplasmic reticulum-Golgi intermediate compartment (ortholog); Golgi apparatus (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,4-dinitrotoluene
AGR Description: Predicted to have mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; predicted to be involved in N-glycan processing; predicted to localize to the cytoplasm and intracellular organelle; orthologous to human MAN1A1 (mannosidase alpha class 1A member 1).
Merged Description: Predicted to have mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; predicted to be involved in N-glycan processing; predicted to localize to the cytoplasm and intracellular organelle; orthologous to human MAN1A1 (mannosidase alpha class 1A member 1); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; N-linked glycan biosynthetic pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Aa2-166; LOC294567; Man1a; mannosidase 1, alpha; mannosyl-oligosaccharide 1,2-alpha-mannosidase IA; mannosyl-oligosaccharide alpha-1,2-mannosidase
Orthologs:
Homo sapiens (human) : MAN1A1 (mannosidase alpha class 1A member 1)  HGNC  Alliance
Mus musculus (house mouse) : Man1a (mannosidase 1, alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Man1a1 (mannosidase alpha class 1A member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MAN1A1 (mannosidase alpha class 1A member 1)
Canis lupus familiaris (dog) : MAN1A1 (mannosidase alpha class 1A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Man1a1 (mannosidase alpha class 1A member 1)
Sus scrofa (pig) : MAN1A1 (mannosidase alpha class 1A member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02035,257,688 - 35,450,132 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02037,014,560 - 37,204,461 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42032,582,507 - 32,766,761 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12032,597,679 - 32,672,777 (-)NCBI
Celera2034,596,324 - 34,772,507 (-)NCBICelera
Cytogenetic Map20q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Man1a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310891
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.