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Gene: Ppil6 (peptidylprolyl isomerase like 6) Rattus norvegicus

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Symbol:

Ppil6

Name:

peptidylprolyl isomerase like 6

RGD ID:

1592581

Description:

Predicted to be active in cytoplasm. Orthologous to human PPIL6 (peptidylprolyl isomerase like 6); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC685567; peptidyl-prolyl cis-trans isomerase-like 6; peptidylprolyl isomerase (cyclophilin)-like 6; probable inactive peptidyl-prolyl cis-trans isomerase-like 6; similar to peptidylprolyl isomerase (cyclophilin)-like 6

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PPIL6 (peptidylprolyl isomerase like 6)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Ppil6 (peptidylprolyl isomerase (cyclophilin)-like 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ppil6 (peptidylprolyl isomerase like 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PPIL6 (peptidylprolyl isomerase like 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PPIL6 (peptidylprolyl isomerase like 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ppil6 (peptidylprolyl isomerase like 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PPIL6 (peptidylprolyl isomerase like 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PPIL6 (peptidylprolyl isomerase like 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ppil6 (peptidylprolyl isomerase like 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	C1QL3 (complement C1q like 3)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	PPIL6 (peptidylprolyl isomerase like 6)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ppil6 (peptidylprolyl isomerase (cyclophilin)-like 6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ppil6 (peptidylprolyl isomerase (cyclophilin)-like 6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	T22F3.12	Alliance	DIOPT (OrthoFinder\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	ppil6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	zar1l2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	46,571,937 - 46,600,759 (+)	NCBI		GRCr8
mRatBN7.2	20	44,989,509 - 45,017,833 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	44,988,943 - 45,018,340 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	20	46,215,317 - 46,244,522 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	46,215,379 - 46,243,707 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	47,907,634 - 47,936,073 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	45,452,083 - 45,479,879 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	20	54,935,648 - 54,964,134 (-)	NCBI		Celera
Cytogenetic Map	20	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease type 4 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (ISO)

1,2-dichloroethane (ISO)

17beta-estradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

6-propyl-2-thiouracil (EXP)

all-trans-retinoic acid (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

cyclosporin A (ISO)

dorsomorphin (ISO)

isoprenaline (ISO)

niclosamide (ISO)

paracetamol (EXP,ISO)

perfluorononanoic acid (ISO)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

rotenone (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

cytoplasm (IBA)

Molecular Function

peptidyl-prolyl cis-trans isomerase activity (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:20676357

Genomics

Comparative Map Data

Ppil6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	46,571,937 - 46,600,759 (+)	NCBI		GRCr8
mRatBN7.2	20	44,989,509 - 45,017,833 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	44,988,943 - 45,018,340 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	20	46,215,317 - 46,244,522 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	46,215,379 - 46,243,707 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	47,907,634 - 47,936,073 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	45,452,083 - 45,479,879 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	20	54,935,648 - 54,964,134 (-)	NCBI		Celera
Cytogenetic Map	20	q12	NCBI

PPIL6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	109,390,215 - 109,441,171 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	109,390,215 - 109,441,171 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	109,711,418 - 109,762,374 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	109,820,624 - 109,868,524 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	109,820,623 - 109,868,522	NCBI
Celera	6	110,458,002 - 110,508,958 (-)	NCBI		Celera
Cytogenetic Map	6	q21	NCBI
HuRef	6	107,277,598 - 107,328,460 (-)	NCBI		HuRef
CHM1_1	6	109,974,514 - 110,025,457 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	110,568,252 - 110,619,209 (-)	NCBI		T2T-CHM13v2.0

Ppil6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	41,366,414 - 41,390,286 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	41,366,435 - 41,390,282 (+)	Ensembl		GRCm39 Ensembl
GRCm38	10	41,490,371 - 41,514,295 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	41,490,439 - 41,514,286 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	41,210,245 - 41,234,094 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	41,178,854 - 41,202,705 (+)	NCBI		MGSCv36	mm8
Celera	10	42,376,692 - 42,400,533 (+)	NCBI		Celera
Cytogenetic Map	10	B1- B2	NCBI
cM Map	10	22.43	NCBI

Ppil6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955411	34,452,864 - 34,481,366 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955411	34,449,508 - 34,481,370 (-)	NCBI	ChiLan1.0	ChiLan1.0

PPIL6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	129,401,324 - 129,449,274 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	127,292,657 - 127,340,623 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	107,193,192 - 107,244,193 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	111,242,022 - 111,292,657 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	111,242,022 - 111,292,657 (-)	Ensembl	panpan1.1		panPan2

PPIL6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	66,316,326 - 66,347,991 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	66,316,425 - 66,342,950 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	66,135,976 - 66,167,216 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	67,198,984 - 67,230,466 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	67,196,646 - 67,231,936 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	66,549,196 - 66,580,435 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	66,398,045 - 66,429,274 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	66,669,784 - 66,701,009 (-)	NCBI		UU_Cfam_GSD_1.0

Ppil6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	101,258,089 - 101,290,271 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936564	5,533,417 - 5,565,759 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936564	5,533,417 - 5,565,105 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PPIL6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	75,463,222 - 75,508,244 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	75,465,290 - 75,508,250 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	84,743,267 - 84,786,213 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PPIL6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	64,426,995 - 64,472,167 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666040	36,718,780 - 36,766,355 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ppil6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624916	667,163 - 697,803 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624916	671,373 - 697,867 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	59
Count of miRNA genes:	55
Interacting mature miRNAs:	58
Transcripts:	ENSRNOT00000066634, ENSRNOT00000068693
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4889610	Pancm3	Pancreatic morphology QTL 3	3.75	0.001	pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	20	4189476	49189476	Rat
2303587	Bw93	Body weight QTL 93	13		body mass (VT:0001259)	body weight (CMO:0000012)	20	26689362	56021148	Rat
1598858	Cm61	Cardiac mass QTL 61	3.6		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	20	8216359	53216359	Rat
1331747	Hrtrt16	Heart rate QTL 16	3.163		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	20	26792353	56021148	Rat
1598816	Memor12	Memory QTL 12	2.4		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	20	12243242	49189476	Rat
2303626	Vencon10	Ventilatory control QTL 10		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	20	20745585	56021148	Rat
2303578	Gluco50	Glucose level QTL 50	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	20	26689362	56021148	Rat
1598869	Memor6	Memory QTL 6	3.1		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	20	26689362	56021148	Rat
1598870	Bp289	Blood pressure QTL 289	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	20	8216359	53216359	Rat
2300188	Bmd68	Bone mineral density QTL 68	6.4	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	20	26689362	56021148	Rat

Markers in Region

BE106860

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	45,011,117 - 45,011,282 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	46,237,490 - 46,237,654	NCBI	Rnor6.0
Rnor_5.0	20	47,929,845 - 47,930,009	UniSTS	Rnor5.0
RGSC_v3.4	20	45,473,662 - 45,473,826	UniSTS	RGSC3.4
Celera	20	54,942,524 - 54,942,688	UniSTS
RH 3.4 Map	20	485.5	UniSTS
Cytogenetic Map	20	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	10	49	113	91	90	59	25	59	6	217	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001432371	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001432372	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_197281	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001064326	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_002725882	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017588088	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601826	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099297	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAXUCZ010000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000066634 ⟹ ENSRNOP00000061264

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	44,988,943 - 45,018,340 (+)	Ensembl
Rnor_6.0 Ensembl	20	46,215,379 - 46,236,848 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000068693 ⟹ ENSRNOP00000061000

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	44,989,528 - 45,018,272 (+)	Ensembl
Rnor_6.0 Ensembl	20	46,215,379 - 46,243,707 (+)	Ensembl

RefSeq Acc Id:

XM_001064326 ⟹ XP_001064326

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	46,571,937 - 46,600,759 (+)	NCBI
mRatBN7.2	20	44,989,509 - 45,017,833 (+)	NCBI
Rnor_6.0	20	46,215,318 - 46,244,522 (+)	NCBI
Rnor_5.0	20	47,907,634 - 47,936,073 (+)	NCBI
RGSC_v3.4	20	45,452,083 - 45,479,879 (+)	RGD

Sequence:

show sequence

GCCACGCGGTTGCCGTGACGACTTGCATTATTTGTGTTCCGGGCTTTCCGCTAGCTCTGCCATG
GCCTCTCAGCAGCCGTGCCGGCCGAAGACGAAGCCCCCCGAGTGCCAAACGGAGTTGCCTCCGG
AGCCGCCGCTGAAGCTGAAGGTGGTGGGGCTCTTCAAAAGCTCCAGCTTTCAGATGTCGAAGAC
CATCGCTGAGACTTTGAAAGCCAATTACCCATCCAGATTCGAAGATCCTGTGATAATTCCTCTT
CAAGAATTTGCTTGGGATCGGTATCTGGAGGAGAAAAAGAGGGAACTGAAGGGTGAAACCTGGG
TCTATTCCTCCTATGTGATATGCTTTATCAATGACCAGCTCCTGGGTAACGCACTTGATCTGAA
GAAGTGGGCCCAGAAGGTGTGGGATGTGGTCGATATCCGGCCCAGTGCACTGTACGAGGCGCTT
ACTCTGGACTATGCCACGAAGTTCTTGAAGGACACCAAGCATGATTTTGTGTTCTTGGACATTA
GTATTGATCTTGCTCCAATTGGAAGGCTGATTTTTGAACTATATTGTGATGCGTGCCCCAGAAC
ATGTACAAATTTTCAGGTCTTGTGCACAGGAACATCAGGGTTTTCTGAGAGAGGCATAAAGCTT
CACTACAAAGATTCGATTTTTCATCGAGTAGTCAAGAACGGTTGGGTACAAGGAGGAGATATAG
TAGAAGGACGAGGGGATGACGGAGAGTCTATTTATGGACCAACGTTTGAAGATGAAAACTTTTC
GGTTCCTCATAATAAGCGGGGAGTTCTTGGAATGGTCAACAAAGGGCATCATACCAATGGTTCG
CAATTCTACATCACACTGCAAGCAACTCCCTATCTGGATAAAAAATACGTGGCTTTTGGGCAAC
TCATTGAAGGAACCGAAGTTCTTAGACGTCTCGAATTAGTCCCAACAGAGAACGAAAGACCGTT
GGTCCTTTGCAGTATCACAGACAGTGGGATTCTTTATACATGATTTTCACACCAGTCACCTTCT
CCGTGGTGCTTTGTTGCTGTGCATTTGGTCAGCTGTTCCTATCTTTAATTAAATGGTGCTTGAT
AATATTGGGAGGCAATGGCAGACACAGCAGGCTGTGTCTAACACTTCATCATTGCCCCCTTTCC
TCTCCCCCCCCCCCCATCACACAGGCTACAAAAACAAAATACTCAGTTTCCTGGGCTCCTTTAC
AACGGAGAGCCATTTGAGAGCACCGTGGCTAATGGGTCAGAGGGAAGCCAGCGATCTGGCTCCC
ACTCCTTCTTGAATACAGATAGGCTGGAAGCCAGGGCCACTGCTGGGCTGTCAGCCTCAGCCTT
ACCACCTCCTATTTCTGGTCTTTTTTACTACACAAGGCAGAAAGACCTCTCGGTTCTATTCCCG
GTGGCTCTTTTGTTACTCGTGGCTTTGAACATTATTAACCTAGCAATGTACCAAGTGATTTTTT
AAATCTAAAGCATTTGTAAATGAATTGTCCTGTTTGTTACTAATTGCTGTCATGATAAACTTGG
TAACTCACTAACACAACAGCAGAAACAACTGAGCATGAAGTTACCTTGCTGTGCCTAGCATGCA
GGGAGGACACGTGTATTAGATGTTGTAAATAGAATCTGTGTCTATGAGCCATGCCAACCATATG
AACAGCAAGGGCTTGGGTTGGTCCTTGTGGTAGATCCCAATGGACATTGCCAGAGCTCTGTTTT
ATCAGTTGCCGCTCCCTCTGAAGGTCCCTGTGATGGTTTGCATATGCTTGGTCCAGGGACTGGC
ACTATTAGAAGGTGTGGCCTTGTTGG

hide sequence

RefSeq Acc Id:

XM_017601826 ⟹ XP_017457315

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	46,571,937 - 46,600,759 (+)	NCBI
mRatBN7.2	20	44,989,509 - 45,017,833 (+)	NCBI
Rnor_6.0	20	46,215,317 - 46,244,522 (+)	NCBI

Sequence:

show sequence

AGCCACGCGGTTGCCGTGACGACTTGCATTATTTGTGTTCCGGGCTTTCCGCTAGCTCTGCCAT
GGCCTCTCAGCAGCCGTGCCGGCCGAAGACGAAGCCCCCCGAGTGCCAAACGGAGTTGCCTCCG
GAGCCGCCGCTGAAGCTGAAGGTGGTGGGGCTCTTCAAAAGCTCCAGCTTTCAGATGTCGAAGA
CCATCGCTGAGACTTTGAAAGCCAATTACCCATCCAGATTCGAAGATCCTGTGATAATTCCTCT
TCAAGAATTTGCTTGGGATCGGTATCTGGAGGAGAAAAAGAGGGAACTGAAGGGTGAAACCTGG
GTCTATTCCTCCTATGTGATATGCTTTATCAATGACCAGCTCCTGGGTAACGCACTTGATCTGA
AGAAGTGGGCCCAGAAGGTGTGGGATGTGGTCGATATCCGGCCCAGTGCACTGTACGAGGCGCT
TACTCTGGACTATGCCACGAAGTTCTTGAAGGACACCAAGCATGATTTTGTGTTCTTGGACATT
AGTATTGATCTTGCTCCAATTGGAAGGCTGATTTTTGAACTATATTGTGATGCGTGCCCCAGAA
CATGTACAAATTTTCAGGTCTTGTGCACAGGAACATCAGGGTTTTCTGAGAGAGGCATAAAGCT
TCACTACAAAGATTCGATTTTTCATCGAGTAGTCAAGAACGGTTGGGTACAAGGAGGAGATATA
GTAGAAGGACGAGGGGATGACGGAGAGTCTATTTATGGACCAACGTTTGAAGATGAAAACTTTT
CGGTTCCTCATAATAAGCGGGGAGTTCTTGGAATGGTCAACAAAGGGCATCATACCAATGGTTC
GCAATTCTACATCACACTGCAAGCAACTCCCTATCTGGATAAAAAATACGTGGCTTTTGGGCTT
CATTCTATCCTGTACATGCCTCACCTGCATGACGACATCATCCCACACTCTGGCACATATGTGA
ACATACGTGAAGCAGTGAGTGGGTCTTGCATATCTTGGACCCTATACTCAGCACACAGCAACTC
ATTGAAGGAACCGAAGTTCTTAGACGTCTCGAATTAGTCCCAACAGAGAACGAAAGACCGTTGG
TCCTTTGCAGTATCACAGACAGTGGGATTCTTTATACATGATTTTCACACCAGTCACCTTCTCC
GTGGTGCTTTGTTGCTGTGCATTTGGTCAGCTGTTCCTATCTTTAATTAAATGGTGCTTGATAA
TATTGGGAGGCAATGGCAGACACAGCAGGCTGTGTCTAACACTTCATCATTGCCCCCTTTCCTC
TCCCCCCCCCCCCATCACACAGGCTACAAAAACAAAATACTCAGTTTCCTGGGCTCCTTTACAA
CGGAGAGCCATTTGAGAGCACCGTGGCTAATGGGTCAGAGGGAAGCCAGCGATCTGGCTCCCAC
TCCTTCTTGAATACAGATAGGCTGGAAGCCAGGGCCACTGCTGGGCTGTCAGCCTCAGCCTTAC
CACCTCCTATTTCTGGTCTTTTTTACTACACAAGGCAGAAAGACCTCTCGGTTCTATTCCCGGT
GGCTCTTTTGTTACTCGTGGCTTTGAACATTATTAACCTAGCAATGTACCAAGTGATTTTTTAA
ATCTAAAGCATTTGTAAATGAATTGTCCTGTTTGTTACTAATTGCTGTCATGATAAACTTGGTA
ACTCACTAACACAACAGCAGAAACAACTGAGCATGAAGTTACCTTGCTGTGCCTAGCATGCAGG
GAGGACACGTGTATTAGATGTTGTAAATAGAATCTGTGTCTATGAGCCATGCCAACCATATGAA
CAGCAAGGGCTTGGGTTGGTCCTTGTGGTAGATCCCAATGGACATTGCCAGAGCTCTGTTTTAT
CAGTTGCCGCTCCCTCTGAAGGTCCCTGTGATGGTTTGCATATGCTTGGTCCAGGGACTGGCAC
TATTAGAAGGTGTGGCCTTGTTGG

hide sequence

RefSeq Acc Id:

XM_039099297 ⟹ XP_038955225

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	46,571,937 - 46,596,871 (+)	NCBI
mRatBN7.2	20	44,989,509 - 45,014,031 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001419300	(Get FASTA)	NCBI Sequence Viewer
	NP_001419301	(Get FASTA)	NCBI Sequence Viewer
	XP_001064326	(Get FASTA)	NCBI Sequence Viewer
	XP_017457315	(Get FASTA)	NCBI Sequence Viewer
	XP_038955225	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000061000.2
	ENSRNOP00000061264.3

RefSeq Acc Id:

XP_001064326 ⟸ XM_001064326

- Peptide Label:

isoform X2

- Sequence:

show sequence

MASQQPCRPKTKPPECQTELPPEPPLKLKVVGLFKSSSFQMSKTIAETLKANYPSRFEDPVIIP
LQEFAWDRYLEEKKRELKGETWVYSSYVICFINDQLLGNALDLKKWAQKVWDVVDIRPSALYEA
LTLDYATKFLKDTKHDFVFLDISIDLAPIGRLIFELYCDACPRTCTNFQVLCTGTSGFSERGIK
LHYKDSIFHRVVKNGWVQGGDIVEGRGDDGESIYGPTFEDENFSVPHNKRGVLGMVNKGHHTNG
SQFYITLQATPYLDKKYVAFGQLIEGTEVLRRLELVPTENERPLVLCSITDSGILYT

hide sequence

RefSeq Acc Id:

XP_017457315 ⟸ XM_017601826

- Peptide Label:

isoform X1

- Sequence:

show sequence

MASQQPCRPKTKPPECQTELPPEPPLKLKVVGLFKSSSFQMSKTIAETLKANYPSRFEDPVIIP
LQEFAWDRYLEEKKRELKGETWVYSSYVICFINDQLLGNALDLKKWAQKVWDVVDIRPSALYEA
LTLDYATKFLKDTKHDFVFLDISIDLAPIGRLIFELYCDACPRTCTNFQVLCTGTSGFSERGIK
LHYKDSIFHRVVKNGWVQGGDIVEGRGDDGESIYGPTFEDENFSVPHNKRGVLGMVNKGHHTNG
SQFYITLQATPYLDKKYVAFGLHSILYMPHLHDDIIPHSGTYVNIREAVSGSCISWTLYSAHSN
SLKEPKFLDVSN

hide sequence

Ensembl Acc Id:

ENSRNOP00000061000 ⟸ ENSRNOT00000068693

Ensembl Acc Id:

ENSRNOP00000061264 ⟸ ENSRNOT00000066634

RefSeq Acc Id:	XP_038955225 ⟸ XM_039099297
- Peptide Label:	isoform X3

Protein Domains

PPIase cyclophilin-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A1I9-F1-model_v2	AlphaFold	D4A1I9	1-313	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701666

Promoter ID:

EPDNEW_R12187

Type:

single initiation site

Name:

Ppil6_1

Description:

peptidylprolyl isomerase like 6

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	46,215,360 - 46,215,420	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1592581	AgrOrtholog
BioCyc Gene	G2FUF-3395	BioCyc
Ensembl Genes	ENSRNOG00000043186	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000066634.3	UniProtKB/TrEMBL
	ENSRNOT00000068693.4	UniProtKB/TrEMBL
Gene3D-CATH	2.40.100.10	UniProtKB/TrEMBL
InterPro	Cyclophilin-like_dom	UniProtKB/TrEMBL
	PPIase_cyclophilin	UniProtKB/TrEMBL
KEGG Report	rno:685567	UniProtKB/TrEMBL
NCBI Gene	685567	ENTREZGENE
PANTHER	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE	UniProtKB/TrEMBL
	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED	UniProtKB/TrEMBL
Pfam	Pro_isomerase	UniProtKB/TrEMBL
PhenoGen	Ppil6	PhenoGen
PRINTS	CSAPPISMRASE	UniProtKB/TrEMBL
PROSITE	CSA_PPIASE_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000043186	RatGTEx
Superfamily-SCOP	SSF50891	UniProtKB/TrEMBL
UniProt	D4A1I9	ENTREZGENE, UniProtKB/TrEMBL
	D4A5Z2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-02	Ppil6	peptidylprolyl isomerase like 6	Ppil6	peptidylprolyl isomerase (cyclophilin)-like 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-05-24	Ppil6	peptidylprolyl isomerase (cyclophilin)-like 6	LOC684245	similar to peptidylprolyl isomerase (cyclophilin)-like 6	Data merged from RGD:1592702	1643240	APPROVED
2008-03-05	Ppil6	peptidylprolyl isomerase (cyclophilin)-like 6	LOC685567	similar to peptidylprolyl isomerase (cyclophilin)-like 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-20	LOC685567	similar to peptidylprolyl isomerase (cyclophilin)-like 6			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-20	LOC684245	similar to peptidylprolyl isomerase (cyclophilin)-like 6			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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