Gene: Plcb4 (phospholipase C, beta 4) Rattus norvegicus
Symbol: Plcb4
Name: phospholipase C, beta 4
Description: ENCODES a protein that exhibits mitogen-activated protein kinase binding; INVOLVED IN negative regulation of potassium ion transport; modulation of chemical synaptic transmission (ortholog); PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; protein kinase C (PKC) signaling pathway; Alzheimer's disease pathway; ASSOCIATED WITH Auriculo-Condylar Syndrome (ortholog); Auriculocondylar Syndrome 2 (ortholog); genetic disease (ortholog); FOUND IN cytoplasm; dendrite (ortholog); glutamatergic synapse (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,3-dinitrobenzene; 3,3',4,4',5-pentachlorobiphenyl
Type: protein-coding
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4; Beta4aa; phosphoinositide phospholipase C; phosphoinositide phospholipase C-beta-4; Phospholipase C (BETA4); Phospholipase C beta4; phospholipase C-beta-4; PLC-beta-4; RATBETA4AA
Homo sapiens (human) : PLCB4 (phospholipase C beta 4)  HGNC  Alliance
Mus musculus (house mouse) : Plcb4 (phospholipase C, beta 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plcb4 (phospholipase C beta 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PLCB4 (phospholipase C beta 4)
Canis lupus familiaris (dog) : PLCB4 (phospholipase C beta 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plcb4 (phospholipase C beta 4)
Sus scrofa (pig) : PLCB4 (phospholipase C beta 4)
more info ...
Allele / Splice: Plcb4_v1   Plcb4_v2  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03128,601,163 - 128,971,720 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03135,089,551 - 135,459,248 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43123,706,313 - 124,077,381 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13123,611,885 - 123,982,941 (+)NCBI
Celera3121,694,557 - 122,062,160 (+)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Plcb4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3345
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE