Jarid2 (jumonji and AT-rich interaction domain containing 2) - Rat Genome Database

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Gene: Jarid2 (jumonji and AT-rich interaction domain containing 2) Rattus norvegicus
Analyze
Symbol: Jarid2
Name: jumonji and AT-rich interaction domain containing 2
RGD ID: 1591663
Description: Predicted to enable several functions, including chromatin binding activity; ubiquitin binding activity; and ubiquitin-modified histone reader activity. Predicted to contribute to histone H3K27 methyltransferase activity. Involved in negative regulation of cardiac muscle cell proliferation and negative regulation of cardiac muscle hypertrophy. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be part of ESC/E(Z) complex and chromatin. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human JARID2 (jumonji and AT-rich interaction domain containing 2); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: jumonji, AT rich interactive domain 2; LOC681740; similar to jumonji protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81719,983,217 - 20,163,598 (-)NCBIGRCr8
mRatBN7.21719,777,487 - 19,957,696 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1719,777,266 - 19,955,690 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01720,183,440 - 20,365,219 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1720,184,245 - 20,364,714 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01722,193,534 - 22,368,495 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1719,477,856 - 19,658,598 (-)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (ISO)
8-Br-cAMP  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butan-1-ol  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
camptothecin  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cisplatin  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
geraniol  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
isoprenaline  (ISO)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
oxaliplatin  (EXP)
panobinostat  (ISO)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
quartz  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
testosterone  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
triphenyl phosphate  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Induction by left ventricular overload and left ventricular failure of the human Jumonji gene (JARID2) encoding a protein that regulates transcription and reexpression of a protective fetal program. Bovill E, etal., J Thorac Cardiovasc Surg. 2008 Sep;136(3):709-16. doi: 10.1016/j.jtcvs.2008.02.020. Epub 2008 Jun 9.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. SET for life: biochemical activities and biological functions of SET domain-containing proteins. Herz HM, etal., Trends Biochem Sci. 2013 Dec;38(12):621-39. doi: 10.1016/j.tibs.2013.09.004. Epub 2013 Oct 20.
4. miRNA-204 drives cardiomyocyte proliferation via targeting Jarid2. Liang D, etal., Int J Cardiol. 2015 Dec 15;201:38-48. doi: 10.1016/j.ijcard.2015.06.163. Epub 2015 Jul 2.
5. Immune function genes CD99L2, JARID2 and TPO show association with autism spectrum disorder. Ramos PS, etal., Mol Autism. 2012 Jun 9;3(1):4. doi: 10.1186/2040-2392-3-4.
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Loss of MicroRNA-155 protects the heart from pathological cardiac hypertrophy. Seok HY, etal., Circ Res. 2014 May 9;114(10):1585-95. doi: 10.1161/CIRCRESAHA.114.303784. Epub 2014 Mar 21.
10. Occupying chromatin: Polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put. Simon JA and Kingston RE, Mol Cell. 2013 Mar 7;49(5):808-24. doi: 10.1016/j.molcel.2013.02.013.
Additional References at PubMed
PMID:9376320   PMID:11301191   PMID:12890668   PMID:15870077   PMID:19010785   PMID:20064375   PMID:20064376   PMID:20075857   PMID:20439489   PMID:26523946   PMID:30253332   PMID:31451685  


Genomics

Comparative Map Data
Jarid2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81719,983,217 - 20,163,598 (-)NCBIGRCr8
mRatBN7.21719,777,487 - 19,957,696 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1719,777,266 - 19,955,690 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01720,183,440 - 20,365,219 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1720,184,245 - 20,364,714 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01722,193,534 - 22,368,495 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1719,477,856 - 19,658,598 (-)NCBICelera
Cytogenetic Map17p14NCBI
JARID2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38615,246,069 - 15,522,042 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl615,246,069 - 15,522,042 (+)EnsemblGRCh38hg38GRCh38
GRCh37615,246,300 - 15,522,273 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36615,354,506 - 15,630,232 (+)NCBINCBI36Build 36hg18NCBI36
Build 34615,354,505 - 15,630,232NCBI
Celera616,484,424 - 16,760,206 (+)NCBICelera
Cytogenetic Map6p22.3NCBI
HuRef615,193,519 - 15,469,507 (+)NCBIHuRef
CHM1_1615,248,791 - 15,524,763 (+)NCBICHM1_1
T2T-CHM13v2.0615,119,264 - 15,395,212 (+)NCBIT2T-CHM13v2.0
Jarid2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391344,881,817 - 45,075,119 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1344,882,950 - 45,075,119 (+)EnsemblGRCm39 Ensembl
GRCm381344,730,774 - 44,921,643 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1344,729,474 - 44,921,643 (+)EnsemblGRCm38mm10GRCm38
MGSCv371344,826,272 - 45,016,350 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361344,741,875 - 44,931,953 (+)NCBIMGSCv36mm8
Celera1345,807,063 - 45,996,635 (+)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1321.66NCBI
Jarid2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955590384,817 - 626,684 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955590383,810 - 512,854 (-)NCBIChiLan1.0ChiLan1.0
JARID2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2529,909,788 - 30,187,083 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1625,898,789 - 26,175,921 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0615,100,415 - 15,376,505 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1615,466,681 - 15,740,928 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl615,466,050 - 15,739,170 (+)Ensemblpanpan1.1panPan2
JARID2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13514,476,656 - 14,737,535 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3514,445,914 - 14,736,158 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3514,425,042 - 14,685,518 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03514,573,294 - 14,834,551 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3514,540,390 - 14,833,877 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13514,399,422 - 14,659,727 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03514,450,826 - 14,711,538 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03515,776,504 - 16,037,565 (+)NCBIUU_Cfam_GSD_1.0
Jarid2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049469,944,101 - 10,164,788 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365521,566,788 - 1,785,490 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365521,566,382 - 1,786,837 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JARID2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl711,359,230 - 11,601,401 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1711,358,243 - 11,601,715 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2711,977,677 - 12,191,165 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JARID2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11756,651,752 - 56,928,650 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1756,651,596 - 56,928,126 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604415,284,556 - 15,562,330 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Jarid2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475610,933,717 - 11,199,077 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475610,932,148 - 11,079,609 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Jarid2
470 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:54
Count of miRNA genes:28
Interacting mature miRNAs:31
Transcripts:ENSRNOT00000070962, ENSRNOT00000071374
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
631499Stl1Serum triglyceride level QTL 13.6blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)17327139827389946Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17435448727028127Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
1582224Epfw4Epididymal fat weight QTL 43.50.0058epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)17920136523653323Rat
1582225Bw67Body weight QTL 676.20.0001body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582226Bw64Body weight QTL 644.20.0017body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1582208Kidm32Kidney mass QTL 323.90.0018kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17920136523653323Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1549900Iddm20Insulin dependent diabetes mellitus QTL 203.7pancreas integrity trait (VT:0010560)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)171398677321975515Rat
1331720Rf43Renal function QTL 432.881kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)171533061323017269Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17429913035837242Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)17429913021293263Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17131990913Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
1582258Bw76Body weight QTL 764.60.0005body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat
1582199Insul5Insulin level QTL 53.40.0119blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)17920136523653323Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17435448727028127Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)17211514921881669Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
1582241Bw70Body weight QTL 704.60.0003body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582245Bw73Body weight QTL 734.60.0004body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122871563Rat

Markers in Region
D13Mit179  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21719,924,168 - 19,924,242 (+)MAPPERmRatBN7.2
Rnor_6.01720,332,077 - 20,332,150NCBIRnor6.0
Rnor_5.01722,336,422 - 22,336,495UniSTSRnor5.0
RGSC_v3.41725,742,449 - 25,742,522UniSTSRGSC3.4
Celera1719,625,945 - 19,626,018UniSTS
RH129878  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21719,776,508 - 19,776,658 (+)MAPPERmRatBN7.2
Rnor_6.01720,182,180 - 20,182,329NCBIRnor6.0
Rnor_5.01722,192,935 - 22,193,084UniSTSRnor5.0
Celera1719,476,874 - 19,477,023UniSTS
RH 3.4 Map17248.3UniSTS
RH140095  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21719,926,075 - 19,926,293 (+)MAPPERmRatBN7.2
Rnor_6.01720,333,688 - 20,333,905NCBIRnor6.0
Rnor_5.01722,337,783 - 22,338,000UniSTSRnor5.0
RGSC_v3.41725,744,389 - 25,744,606UniSTSRGSC3.4
Celera1719,627,851 - 19,628,068UniSTS
RH 3.4 Map17246.9UniSTS
Jarid2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21719,797,274 - 19,797,498 (+)MAPPERmRatBN7.2
Rnor_6.01720,202,407 - 20,202,630NCBIRnor6.0
Rnor_5.01722,213,019 - 22,213,242UniSTSRnor5.0
Celera1719,497,646 - 19,497,869UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 28 40 24 19 24 2 2 74 35 41 11 2
Low 15 17 17 17 6 9 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001427247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006222365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006253776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008771567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008773944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017587710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017587711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017587712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017587713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017587714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000070962   ⟹   ENSRNOP00000067055
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1719,777,266 - 19,955,690 (-)Ensembl
Rnor_6.0 Ensembl1720,184,245 - 20,364,714 (-)Ensembl
RefSeq Acc Id: NM_001427247   ⟹   NP_001414176
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81719,983,217 - 20,161,970 (-)NCBI
RefSeq Acc Id: XM_017600707   ⟹   XP_017456196
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81719,983,217 - 20,064,939 (-)NCBI
mRatBN7.21719,777,487 - 19,852,919 (-)NCBI
Rnor_6.01720,183,440 - 20,261,913 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600708   ⟹   XP_017456197
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81719,983,217 - 20,162,568 (-)NCBI
mRatBN7.21719,777,487 - 19,956,496 (-)NCBI
Rnor_6.01720,183,440 - 20,364,717 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600709   ⟹   XP_017456198
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81719,983,217 - 20,163,119 (-)NCBI
mRatBN7.21719,777,487 - 19,957,039 (-)NCBI
Rnor_6.01720,183,440 - 20,365,219 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600710   ⟹   XP_017456199
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81719,983,217 - 20,162,568 (-)NCBI
mRatBN7.21719,777,487 - 19,956,496 (-)NCBI
Rnor_6.01720,183,440 - 20,364,717 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600711   ⟹   XP_017456200
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81719,983,217 - 20,159,450 (-)NCBI
mRatBN7.21719,777,487 - 19,953,367 (-)NCBI
Rnor_6.01720,183,440 - 20,278,256 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039096472   ⟹   XP_038952400
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81719,983,217 - 20,159,635 (-)NCBI
mRatBN7.21719,777,487 - 19,953,574 (-)NCBI
RefSeq Acc Id: XM_039096474   ⟹   XP_038952402
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81719,983,217 - 20,163,598 (-)NCBI
mRatBN7.21719,777,487 - 19,957,696 (-)NCBI
RefSeq Acc Id: XM_063276746   ⟹   XP_063132816
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81719,983,217 - 20,159,450 (-)NCBI
RefSeq Acc Id: XM_063276747   ⟹   XP_063132817
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81719,983,217 - 20,159,870 (-)NCBI
RefSeq Acc Id: XP_017456198   ⟸   XM_017600709
- Peptide Label: isoform X3
- UniProtKB: M0RBV7 (UniProtKB/TrEMBL),   A6J730 (UniProtKB/TrEMBL),   A6J731 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456199   ⟸   XM_017600710
- Peptide Label: isoform X3
- UniProtKB: M0RBV7 (UniProtKB/TrEMBL),   A6J730 (UniProtKB/TrEMBL),   A6J731 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456197   ⟸   XM_017600708
- Peptide Label: isoform X3
- UniProtKB: M0RBV7 (UniProtKB/TrEMBL),   A6J730 (UniProtKB/TrEMBL),   A6J731 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456200   ⟸   XM_017600711
- Peptide Label: isoform X4
- UniProtKB: A6J732 (UniProtKB/TrEMBL),   A6J731 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456196   ⟸   XM_017600707
- Peptide Label: isoform X1
- UniProtKB: A6J731 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000067055   ⟸   ENSRNOT00000070962
RefSeq Acc Id: XP_038952402   ⟸   XM_039096474
- Peptide Label: isoform X3
- UniProtKB: M0RBV7 (UniProtKB/TrEMBL),   A6J730 (UniProtKB/TrEMBL),   A6J731 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952400   ⟸   XM_039096472
- Peptide Label: isoform X2
- UniProtKB: A6J731 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001414176   ⟸   NM_001427247
- UniProtKB: A6J730 (UniProtKB/TrEMBL),   M0RBV7 (UniProtKB/TrEMBL),   A6J731 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132817   ⟸   XM_063276747
- Peptide Label: isoform X4
- UniProtKB: A6J731 (UniProtKB/TrEMBL),   A6J732 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132816   ⟸   XM_063276746
- Peptide Label: isoform X4
- UniProtKB: A6J731 (UniProtKB/TrEMBL),   A6J732 (UniProtKB/TrEMBL)
Protein Domains
ARID   JmjC   JmjN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0RBV7-F1-model_v2 AlphaFold M0RBV7 1-1234 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1591663 AgrOrtholog
BioCyc Gene G2FUF-9847 BioCyc
Ensembl Genes ENSRNOG00000045918 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000070962.4 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.60 UniProtKB/TrEMBL
  Cupin UniProtKB/TrEMBL
InterPro ARID/BRIGHT_DNA-bd UniProtKB/TrEMBL
  ARID_dom_sf UniProtKB/TrEMBL
  JmjC_dom UniProtKB/TrEMBL
  TF_JmjN UniProtKB/TrEMBL
  Znf_C5HC2 UniProtKB/TrEMBL
NCBI Gene 681740 ENTREZGENE
PANTHER LYSINE-SPECIFIC DEMETHYLASE UniProtKB/TrEMBL
  PROTEIN JUMONJI UniProtKB/TrEMBL
Pfam ARID UniProtKB/TrEMBL
  JmjC UniProtKB/TrEMBL
  JmjN UniProtKB/TrEMBL
  zf-C5HC2 UniProtKB/TrEMBL
PhenoGen Jarid2 PhenoGen
PROSITE ARID UniProtKB/TrEMBL
  JMJC UniProtKB/TrEMBL
  JMJN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000045918 RatGTEx
SMART ARID UniProtKB/TrEMBL
  BRIGHT UniProtKB/TrEMBL
  JmjC UniProtKB/TrEMBL
  JmjN UniProtKB/TrEMBL
Superfamily-SCOP ARID UniProtKB/TrEMBL
  Clavaminate synthase-like UniProtKB/TrEMBL
UniProt A6J730 ENTREZGENE, UniProtKB/TrEMBL
  A6J731 ENTREZGENE, UniProtKB/TrEMBL
  A6J732 ENTREZGENE, UniProtKB/TrEMBL
  M0RBV7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Jarid2  jumonji and AT-rich interaction domain containing 2  Jarid2  jumonji, AT rich interactive domain 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-09 Jarid2  jumonji, AT rich interactive domain 2  LOC681740  similar to jumonji protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC681740  similar to jumonji protein      Symbol and Name status set to provisional 70820 PROVISIONAL