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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1-naphthyl isothiocyanate | decreases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of PNPLA7 mRNA | CTD | PMID:30723492 | 17beta-estradiol | decreases expression | ISO | RGD:1353397 | 6480464 | Estradiol results in decreased expression of PNPLA7 mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PNPLA7 mRNA | CTD | PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:733340 | 6480464 | Tetrachlorodibenzodioxin affects the expression of PNPLA7 mRNA | CTD | PMID:21570461 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2, 6-dinitrotoluene affects the expression of PNPLA7 mRNA | CTD | PMID:21346803 | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:23196670 | 4-hydroxyphenyl retinamide | decreases expression | ISO | RGD:733340 | 6480464 | Fenretinide results in decreased expression of PNPLA7 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of PNPLA7 mRNA | CTD | PMID:24780913 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of PNPLA7 mRNA | CTD | PMID:31881176 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of PNPLA7 mRNA | CTD | PMID:28959563 | aflatoxin B1 | affects methylation | ISO | RGD:1353397 | 6480464 | Aflatoxin B1 affects the methylation of PNPLA7 intron | CTD | PMID:30157460 | aflatoxin B1 | decreases expression | ISO | RGD:1353397 | 6480464 | Aflatoxin B1 results in decreased expression of PNPLA7 mRNA | CTD | PMID:32234424 | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of PNPLA7 mRNA | CTD | PMID:33354967 | Aflatoxin B2 alpha | affects methylation | ISO | RGD:1353397 | 6480464 | aflatoxin B2 affects the methylation of PNPLA7 intron | CTD | PMID:30157460 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of PNPLA7 mRNA | CTD | PMID:16483693 | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of PNPLA7 mRNA | CTD | PMID:30779732 | aristolochic acid A | increases expression | ISO | RGD:1353397 | 6480464 | aristolochic acid I results in increased expression of PNPLA7 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | RGD:1353397 | 6480464 | Arsenic affects the methylation of PNPLA7 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | RGD:1353397 | 6480464 | Arsenic affects the methylation of PNPLA7 gene | CTD | PMID:25304211 | atrazine | increases expression | ISO | RGD:1353397 | 6480464 | Atrazine results in increased expression of PNPLA7 mRNA | CTD | PMID:22378314 | Benoxacor | decreases expression | ISO | RGD:733340 | 6480464 | benoxacor results in decreased expression of PNPLA7 mRNA | CTD | PMID:34850242 | benzo[a]pyrene | decreases expression | ISO | RGD:733340 | 6480464 | Benzo(a)pyrene results in decreased expression of PNPLA7 mRNA | CTD | PMID:19770486 | benzo[a]pyrene | decreases expression | ISO | RGD:1353397 | 6480464 | Benzo(a)pyrene results in decreased expression of PNPLA7 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | affects methylation | ISO | RGD:1353397 | 6480464 | Benzo(a)pyrene affects the methylation of PNPLA7 intron | CTD | PMID:30157460 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of PNPLA7 mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | ISO | RGD:1353397 | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of PNPLA7 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | ISO | RGD:733340 | 6480464 | bisphenol A results in decreased expression of PNPLA7 mRNA | CTD | PMID:33221593 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PNPLA7 mRNA | CTD | PMID:30816183, PMID:34947998 | buspirone | increases expression | EXP | | 6480464 | Buspirone results in increased expression of PNPLA7 mRNA | CTD | PMID:24136188 | butanal | decreases expression | ISO | RGD:1353397 | 6480464 | butyraldehyde results in decreased expression of PNPLA7 mRNA | CTD | PMID:26079696 | carbon nanotube | increases expression | ISO | RGD:733340 | 6480464 | Nanotubes, Carbon analog results in increased expression of PNPLA7 mRNA | CTD | PMID:25554681 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of PNPLA7 mRNA | CTD | PMID:24386269 | cyclosporin A | decreases methylation | ISO | RGD:1353397 | 6480464 | Cyclosporine results in decreased methylation of PNPLA7 promoter | CTD | PMID:27989131 | cyproconazole | decreases expression | ISO | RGD:733340 | 6480464 | cyproconazole results in decreased expression of PNPLA7 mRNA | CTD | PMID:22334560 | diazinon | increases methylation | ISO | RGD:1353397 | 6480464 | Diazinon results in increased methylation of PNPLA7 gene | CTD | PMID:22964155 | epoxiconazole | decreases expression | ISO | RGD:733340 | 6480464 | epoxiconazole results in decreased expression of PNPLA7 mRNA | CTD | PMID:22334560 | ethanol | increases expression | ISO | RGD:733340 | 6480464 | Ethanol results in increased expression of PNPLA7 mRNA | CTD | PMID:30319688 | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of PNPLA7 mRNA | CTD | PMID:24136188, PMID:24793618 | fulvestrant | multiple interactions | ISO | RGD:1353397 | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of PNPLA7 gene | CTD | PMID:31601247 | furan | decreases expression | EXP | | 6480464 | furan results in decreased expression of PNPLA7 mRNA | CTD | PMID:25539665 | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of PNPLA7 mRNA | CTD | PMID:24136188 | isoprenaline | increases expression | ISO | RGD:733340 | 6480464 | Isoproterenol results in increased expression of PNPLA7 mRNA | CTD | PMID:20003209 | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of PNPLA7 mRNA | CTD | PMID:24136188 | methamphetamine | increases expression | ISO | RGD:733340 | 6480464 | Methamphetamine results in increased expression of PNPLA7 mRNA | CTD | PMID:26307267 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of PNPLA7 mRNA | CTD | PMID:30467583 | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of PNPLA7 gene | CTD | PMID:33148267 | N-Nitrosopyrrolidine | decreases expression | ISO | RGD:1353397 | 6480464 | N-Nitrosopyrrolidine results in decreased expression of PNPLA7 mRNA | CTD | PMID:32234424 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of PNPLA7 mRNA | CTD | PMID:24136188 | nickel atom | decreases expression | ISO | RGD:1353397 | 6480464 | Nickel results in decreased expression of PNPLA7 mRNA | CTD | PMID:24768652, PMID:25583101 | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of PNPLA7 mRNA | CTD | PMID:24136188 | oxycodone | increases expression | EXP | | 6480464 | Oxycodone results in increased expression of PNPLA7 mRNA | CTD | PMID:23439660 | paracetamol | decreases expression | ISO | RGD:1353397 | 6480464 | Acetaminophen results in decreased expression of PNPLA7 mRNA | CTD | PMID:22230336, PMID:29067470 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of PNPLA7 mRNA | CTD | PMID:33387578 | paraquat | increases expression | ISO | RGD:733340 | 6480464 | Paraquat results in increased expression of PNPLA7 mRNA | CTD | PMID:21463325 | parathion | affects expression | ISO | RGD:733340 | 6480464 | Parathion affects the expression of PNPLA7 mRNA | CTD | PMID:34813904 | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of PNPLA7 gene | CTD | PMID:33148267 | pirinixic acid | multiple interactions | ISO | RGD:733340 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of PNPLA7 mRNA | CTD | PMID:19710929 | pravastatin | decreases expression | EXP | | 6480464 | Pravastatin results in decreased expression of PNPLA7 mRNA | CTD | PMID:27225895 | pravastatin | decreases expression | ISO | RGD:733340 | 6480464 | Pravastatin results in decreased expression of PNPLA7 mRNA | CTD | PMID:27225895 | propiconazole | decreases expression | ISO | RGD:733340 | 6480464 | propiconazole results in decreased expression of PNPLA7 mRNA | CTD | PMID:21278054, PMID:22334560 | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of PNPLA7 mRNA | CTD | PMID:28374803 | sevoflurane | affects expression | EXP | | 6480464 | sevoflurane affects the expression of PNPLA7 mRNA | CTD | PMID:15967596 | silver atom | increases expression | ISO | RGD:733340 | 6480464 | Silver results in increased expression of PNPLA7 mRNA | CTD | PMID:27131904 | silver(0) | increases expression | ISO | RGD:733340 | 6480464 | Silver results in increased expression of PNPLA7 mRNA | CTD | PMID:27131904 | sunitinib | increases expression | ISO | RGD:1353397 | 6480464 | Sunitinib results in increased expression of PNPLA7 mRNA | CTD | PMID:31533062 | testosterone | increases expression | ISO | RGD:733340 | 6480464 | Testosterone deficiency results in increased expression of PNPLA7 mRNA | CTD | PMID:33848595 | tetrachloroethene | increases expression | ISO | RGD:733340 | 6480464 | Tetrachloroethylene results in increased expression of PNPLA7 mRNA | CTD | PMID:28973375 | thapsigargin | increases expression | ISO | RGD:1353397 | 6480464 | Thapsigargin results in increased expression of PNPLA7 mRNA | CTD | PMID:22378314 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of PNPLA7 mRNA | CTD | PMID:34492290 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of PNPLA7 mRNA | CTD | PMID:33387578 | Triptolide | increases expression | EXP | | 6480464 | triptolide results in increased expression of PNPLA7 protein | CTD | PMID:32519852 | triptonide | decreases expression | ISO | RGD:733340 | 6480464 | triptonide results in decreased expression of PNPLA7 mRNA | CTD | PMID:33045310 | tris(2-butoxyethyl) phosphate | affects expression | ISO | RGD:1353397 | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of PNPLA7 mRNA | CTD | PMID:29024780 | tungsten | decreases expression | ISO | RGD:733340 | 6480464 | Tungsten results in decreased expression of PNPLA7 mRNA | CTD | PMID:30912803 | tunicamycin | increases expression | ISO | RGD:1353397 | 6480464 | Tunicamycin results in increased expression of PNPLA7 mRNA | CTD | PMID:22378314 | valdecoxib | increases expression | EXP | | 6480464 | valdecoxib results in increased expression of PNPLA7 mRNA | CTD | PMID:24136188 | zaragozic acid A | increases expression | EXP | | 6480464 | squalestatin 1 results in increased expression of PNPLA7 mRNA | CTD | PMID:27225895 | zaragozic acid A | decreases expression | ISO | RGD:733340 | 6480464 | squalestatin 1 results in decreased expression of PNPLA7 mRNA | CTD | PMID:27225895 | |