Pnpla7 (patatin-like phospholipase domain containing 7) - Rat Genome Database

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Gene: Pnpla7 (patatin-like phospholipase domain containing 7) Rattus norvegicus
Analyze
Symbol: Pnpla7
Name: patatin-like phospholipase domain containing 7
RGD ID: 708466
Description: Predicted to enable lysophospholipase activity. Predicted to be involved in phosphatidylcholine catabolic process. Predicted to be located in endoplasmic reticulum membrane and lipid droplet. Predicted to be active in endoplasmic reticulum. Orthologous to human PNPLA7 (patatin like phospholipase domain containing 7); PARTICIPATES IN glycerophospholipid metabolic pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: liver NTE-related protein 1; LOC100911867; MGC108975; neuropathy target esterase like 1; Nte-related; NTE-related esterase; Ntel; Ntel1; patatin-like phospholipase domain-containing protein 7; patatin-like phospholipase domain-containing protein 7-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8328,180,670 - 28,259,673 (+)NCBIGRCr8
mRatBN7.237,782,572 - 7,861,504 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl37,782,572 - 7,861,497 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx310,887,331 - 10,966,646 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0319,473,561 - 19,552,873 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0317,663,405 - 17,742,723 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.032,182,191 - 2,261,890 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl32,182,957 - 2,261,878 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl34,730,990 - 4,772,154 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.032,164,205 - 2,243,127 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.435,122,212 - 5,201,139 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.135,163,825 - 5,201,138 (+)NCBI
Celera32,611,803 - 2,690,723 (+)NCBICelera
Cytogenetic Map3p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 11 of 11 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pnpla7RatAdams-Oliver Syndrome 5  ISOPNPLA7 (Homo sapiens)8554872ClinVar Annotator: match by term: Adams-Oliver syndrome 5ClinVarPMID:16025100 more ...
Pnpla7Ratautosomal dominant intellectual developmental disorder 8  ISOPNPLA7 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorder with or without hyperkinetic movements and seizures and autosomal dominantClinVarPMID:16826528 more ...
Pnpla7RatAutosomal Recessive Peripheral Neuropathy with or without Impaired Intellectual Development  ISOPNPLA7 (Homo sapiens)8554872ClinVar Annotator: match by term: Peripheral neuropathy more ...ClinVarPMID:25741868
Pnpla7Ratdevelopmental and epileptic encephalopathy 14  ISOPNPLA7 (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 14ClinVarPMID:16025100 more ...
Pnpla7Ratepilepsy  ISOPNPLA7 (Homo sapiens)8554872ClinVar Annotator: match by term: EpilepsyClinVar 
Pnpla7RatJoubert syndrome 1  ISOPNPLA7 (Homo sapiens)8554872ClinVar Annotator: match by term: Familial aplasia of the vermisClinVarPMID:16025100 more ...
Pnpla7RatKleefstra syndrome 1  ISOPNPLA7 (Homo sapiens)8554872ClinVar Annotator: match by term: Kleefstra syndrome 1ClinVarPMID:16826528 more ...
Pnpla7Ratmulibrey nanism  ISOPNPLA7 (Homo sapiens)8554872ClinVar Annotator: match by term: Mulibrey nanism syndromeClinVar 
Pnpla7Ratprimary coenzyme Q10 deficiency 7  ISOPNPLA7 (Homo sapiens)8554872ClinVar Annotator: match by term: Neonatal encephalomyopathy-cardiomyopathy-respiratory distress syndromeClinVarPMID:28492532
Pnpla7Ratprimary ovarian insufficiency  ISOPNPLA7 (Homo sapiens)8554872ClinVar Annotator: match by term: Premature ovarian failureClinVarPMID:31042289
Pnpla7RatRafiq syndrome  ISOPNPLA7 (Homo sapiens)8554872ClinVar Annotator: match by term: Rafiq syndromeClinVarPMID:24566669 more ...
1 to 11 of 11 rows

1 to 20 of 94 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pnpla7Rat(1->4)-beta-D-glucan multiple interactionsISOPnpla7 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PNPLA7 mRNACTDPMID:36331819
Pnpla7Rat1-naphthyl isothiocyanate decreases expressionEXP 64804641-Naphthylisothiocyanate results in decreased expression of PNPLA7 mRNACTDPMID:30723492
Pnpla7Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of PNPLA7 mRNACTDPMID:32145629
Pnpla7Rat17beta-estradiol decreases expressionISOPNPLA7 (Homo sapiens)6480464Estradiol results in decreased expression of PNPLA7 mRNACTDPMID:31614463
Pnpla7Rat17beta-estradiol increases expressionISOPnpla7 (Mus musculus)6480464Estradiol results in increased expression of PNPLA7 mRNACTDPMID:39298647
Pnpla7Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of PNPLA7 mRNACTDPMID:21215274
Pnpla7Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOPnpla7 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of PNPLA7 mRNACTDPMID:21570461
Pnpla7Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of PNPLA7 mRNACTDPMID:21346803
Pnpla7Rat3,3',4,4',5-pentachlorobiphenyl decreases expressionEXP 64804643 more ...CTDPMID:23196670
Pnpla7Rat4,4'-sulfonyldiphenol affects expressionISOPnpla7 (Mus musculus)6480464bisphenol S affects the expression of PNPLA7 mRNACTDPMID:39298647
Pnpla7Rat4-hydroxyphenyl retinamide decreases expressionISOPnpla7 (Mus musculus)6480464Fenretinide results in decreased expression of PNPLA7 mRNACTDPMID:28973697
Pnpla7Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of PNPLA7 mRNACTDPMID:24780913 and PMID:30047161
Pnpla7Ratacetamide decreases expressionEXP 6480464acetamide results in decreased expression of PNPLA7 mRNACTDPMID:31881176
Pnpla7Ratacrylamide increases expressionEXP 6480464Acrylamide results in increased expression of PNPLA7 mRNACTDPMID:28959563
Pnpla7Rataflatoxin B1 affects methylationISOPNPLA7 (Homo sapiens)6480464Aflatoxin B1 affects the methylation of PNPLA7 intronCTDPMID:30157460
Pnpla7Rataflatoxin B1 decreases expressionISOPNPLA7 (Homo sapiens)6480464Aflatoxin B1 results in decreased expression of PNPLA7 mRNACTDPMID:32234424
Pnpla7Rataflatoxin B1 decreases expressionEXP 6480464Aflatoxin B1 results in decreased expression of PNPLA7 mRNACTDPMID:33354967
Pnpla7RatAflatoxin B2 alpha affects methylationISOPNPLA7 (Homo sapiens)6480464aflatoxin B2 affects the methylation of PNPLA7 intronCTDPMID:30157460
Pnpla7Ratamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of PNPLA7 mRNACTDPMID:30047161
Pnpla7Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of PNPLA7 mRNACTDPMID:16483693

1 to 20 of 94 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pnpla7Ratlipid catabolic process involved_inIEAUniRule:UR0004002421600115GO_REF:0000104UniProtGO_REF:0000104
Pnpla7Ratlipid catabolic process involved_inIEAUniProtKB-KW:KW-04421600115GO_REF:0000043UniProtGO_REF:0000043
Pnpla7Ratlipid metabolic process involved_inIEAUniProtKB-KW:KW-04431600115GO_REF:0000043UniProtGO_REF:0000043
Pnpla7Ratlipid metabolic process involved_inIEAInterPro:IPR0026411600115GO_REF:0000002InterProGO_REF:0000002
Pnpla7Ratphosphatidylcholine catabolic process involved_inISOPnpla7 (Mus musculus)1624291 PMID:28887301RGDPMID:28887301
Pnpla7Ratphosphatidylcholine catabolic process involved_inIEAUniProtKB:A2AJ88 and ensembl:ENSMUSP000000440781600115GO_REF:0000107EnsemblGO_REF:0000107
Pnpla7Ratphosphatidylcholine catabolic process involved_inISSUniProtKB:A2AJ881600115GO_REF:0000024UniProtGO_REF:0000024

Cellular Component
1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pnpla7Ratendoplasmic reticulum located_inIEAUniProtKB:A2AJ88 and ensembl:ENSMUSP000000440781600115GO_REF:0000107EnsemblGO_REF:0000107
Pnpla7Ratendoplasmic reticulum is_active_inIBAFB:FBgn0003656 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Pnpla7Ratendoplasmic reticulum located_inIEAUniProtKB-KW:KW-02561600115GO_REF:0000043UniProtGO_REF:0000043
Pnpla7Ratendoplasmic reticulum located_inISOPnpla7 (Mus musculus)1624291 PMID:18086666RGDPMID:18086666
Pnpla7Ratendoplasmic reticulum membrane located_inISOPnpla7 (Mus musculus)1624291 PMID:28887301RGDPMID:28887301
Pnpla7Ratendoplasmic reticulum membrane located_inIEAUniProtKB:A2AJ88 and ensembl:ENSMUSP000000440781600115GO_REF:0000107EnsemblGO_REF:0000107
Pnpla7Ratendoplasmic reticulum membrane located_inISSUniProtKB:A2AJ881600115GO_REF:0000024UniProtGO_REF:0000024
Pnpla7Ratendoplasmic reticulum membrane located_inIEAUniProtKB-SubCell:SL-00971600115GO_REF:0000044UniProtGO_REF:0000044
Pnpla7Ratlipid droplet located_inIEAUniProtKB:A2AJ88 and ensembl:ENSMUSP000000440781600115GO_REF:0000107EnsemblGO_REF:0000107
Pnpla7Ratlipid droplet located_inIEAUniProtKB-KW:KW-05511600115GO_REF:0000043UniProtGO_REF:0000043
Pnpla7Ratlipid droplet located_inISOPnpla7 (Mus musculus)1624291 PMID:18086666 and PMID:28887301RGDPMID:18086666 and PMID:28887301
Pnpla7Ratlipid droplet located_inIEAUniProtKB-SubCell:SL-01541600115GO_REF:0000044UniProtGO_REF:0000044
Pnpla7Ratlipid droplet located_inISSUniProtKB:A2AJ881600115GO_REF:0000024UniProtGO_REF:0000024
Pnpla7Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
1 to 14 of 14 rows

Molecular Function
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pnpla7Rathydrolase activity enablesIEAUniRule:UR0004002421600115GO_REF:0000104UniProtGO_REF:0000104
Pnpla7Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Pnpla7Ratlysophospholipase activity enablesIEAARBA:ARBA000357481600115GO_REF:0000117UniProtGO_REF:0000117
Pnpla7Ratlysophospholipase activity enablesIEARHEA:151771600115GO_REF:0000116RHEAGO_REF:0000116
Pnpla7Ratlysophospholipase activity enablesIBAFB:FBgn0003656 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Pnpla7Ratlysophospholipase activity enablesISOPnpla7 (Mus musculus)1624291 PMID:18086666 and PMID:28887301RGDPMID:18086666 and PMID:28887301
Pnpla7Ratlysophospholipase activity enablesIEAUniProtKB:A2AJ88 and ensembl:ENSMUSP000000440781600115GO_REF:0000107EnsemblGO_REF:0000107
Pnpla7Ratlysophospholipase activity enablesIEAEC:3.1.1.51600115GO_REF:0000003UniProtGO_REF:0000003
Pnpla7Ratlysophospholipase activity enablesISSUniProtKB:A2AJ881600115GO_REF:0000024UniProtGO_REF:0000024
1 to 9 of 9 rows

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pnpla7Ratglycerophospholipid metabolic pathway  IEA 6907045 KEGGrno:00564

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Rat NTE-related esterase is a membrane-associated protein, hydrolyzes phenyl valerate, and interacts with diisopropylfluorophosphate through a serine catalytic machinery. Xie M, etal., Arch Biochem Biophys 2003 Aug 15;416(2):137-46.
PMID:12477932   PMID:12640454   PMID:18086666   PMID:22326266   PMID:28887301  



Pnpla7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8328,180,670 - 28,259,673 (+)NCBIGRCr8
mRatBN7.237,782,572 - 7,861,504 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl37,782,572 - 7,861,497 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx310,887,331 - 10,966,646 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0319,473,561 - 19,552,873 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0317,663,405 - 17,742,723 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.032,182,191 - 2,261,890 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl32,182,957 - 2,261,878 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl34,730,990 - 4,772,154 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.032,164,205 - 2,243,127 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.435,122,212 - 5,201,139 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.135,163,825 - 5,201,138 (+)NCBI
Celera32,611,803 - 2,690,723 (+)NCBICelera
Cytogenetic Map3p13NCBI
PNPLA7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389137,459,952 - 137,550,402 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9137,459,952 - 137,550,402 (-)EnsemblGRCh38hg38GRCh38
GRCh379140,354,404 - 140,444,854 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369139,474,226 - 139,564,807 (-)NCBINCBI36Build 36hg18NCBI36
Build 349137,630,241 - 137,720,673NCBI
Celera9110,879,193 - 110,969,453 (-)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9109,818,540 - 109,909,455 (-)NCBIHuRef
CHM1_19140,501,929 - 140,594,079 (-)NCBICHM1_1
T2T-CHM13v2.09149,710,086 - 149,803,830 (-)NCBIT2T-CHM13v2.0
Pnpla7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39224,865,235 - 24,944,084 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl224,866,045 - 24,944,069 (+)EnsemblGRCm39 Ensembl
GRCm38224,975,990 - 25,054,072 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl224,976,033 - 25,054,057 (+)EnsemblGRCm38mm10GRCm38
MGSCv37224,831,553 - 24,909,592 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36224,798,097 - 24,876,064 (+)NCBIMGSCv36mm8
Celera224,699,962 - 24,781,158 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map216.88NCBI
Pnpla7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555135,376,699 - 5,434,581 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555135,376,690 - 5,436,095 (-)NCBIChiLan1.0ChiLan1.0
PNPLA7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2111,826,805 - 1,928,145 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan191,830,080 - 1,930,479 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09108,531,917 - 108,631,119 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19137,496,924 - 137,593,154 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9137,496,924 - 137,593,154 (-)Ensemblpanpan1.1panPan2
PNPLA7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1948,221,754 - 48,286,352 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl948,221,514 - 48,286,352 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha947,408,962 - 47,473,587 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0949,083,836 - 49,148,496 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl949,083,916 - 49,148,495 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1947,860,228 - 47,924,866 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0948,159,209 - 48,223,845 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0948,205,678 - 48,270,340 (+)NCBIUU_Cfam_GSD_1.0
Pnpla7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947202,769,065 - 202,840,510 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936669535,796 - 605,710 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936669535,104 - 605,993 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PNPLA7
(Sus scrofa - pig)		 No map positions available.
PNPLA7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112655,723 - 734,315 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660584,614,234 - 4,694,034 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pnpla7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624760521,145 - 575,431 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Pnpla7
272 total Variants


Assembly: RGSC_v3.4
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
3 5199066 5199067 T G snv SR/JrHsd (MCW) View more Information

Predicted Target Of
Summary Value
Count of predictions:104
Count of miRNA genes:83
Interacting mature miRNAs:92
Transcripts:ENSRNOT00000011633
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 11 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
2292615Ept17Estrogen-induced pituitary tumorigenesis QTL 176.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3653764510778823Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
1358185Ept6Estrogen-induced pituitary tumorigenesis QTL 66.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3653764510778823Rat

1 to 10 of 11 rows
D3Rat87  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8328,210,891 - 28,211,108 (+)Marker Load Pipeline
mRatBN7.237,812,714 - 7,812,933 (+)MAPPERmRatBN7.2
Rnor_6.032,213,097 - 2,213,313NCBIRnor6.0
Rnor_5.032,194,345 - 2,194,561UniSTSRnor5.0
RGSC_v3.435,152,357 - 5,152,573UniSTSRGSC3.4
RGSC_v3.435,152,356 - 5,152,573RGDRGSC3.4
RGSC_v3.135,152,356 - 5,152,573RGD
SHRSP x BN Map32.2599UniSTS
SHRSP x BN Map32.2599RGD
FHH x ACI Map30.0RGD
Cytogenetic Map3p13UniSTS
RH128428  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.237,780,818 - 7,781,002 (+)MAPPERmRatBN7.2
mRatBN7.2885,195,269 - 85,195,453 (+)MAPPERmRatBN7.2
Rnor_6.0891,820,974 - 91,821,157NCBIRnor6.0
Rnor_6.032,181,205 - 2,181,388NCBIRnor6.0
Rnor_5.0891,338,627 - 91,338,810UniSTSRnor5.0
Rnor_5.032,162,453 - 2,162,636UniSTSRnor5.0
RGSC_v3.435,120,460 - 5,120,643UniSTSRGSC3.4
RGSC_v3.4889,362,373 - 89,362,556UniSTSRGSC3.4
Celera884,840,039 - 84,840,222UniSTS
Celera32,610,050 - 2,610,233UniSTS
Cytogenetic Map8q31UniSTS
Cytogenetic Map3p13UniSTS
RH132502  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.237,861,242 - 7,861,452 (+)MAPPERmRatBN7.2
Rnor_6.032,261,624 - 2,261,833NCBIRnor6.0
Rnor_5.032,242,872 - 2,243,081UniSTSRnor5.0
RGSC_v3.435,200,884 - 5,201,093UniSTSRGSC3.4
Celera32,690,468 - 2,690,677UniSTS
RH 3.4 Map1845.3UniSTS
Cytogenetic Map3p13UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000011633   ⟹   ENSRNOP00000011633
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl37,782,572 - 7,861,497 (+)Ensembl
Rnor_6.0 Ensembl32,182,957 - 2,261,878 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000079208
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl37,785,526 - 7,861,497 (+)Ensembl
Rnor_6.0 Ensembl34,730,990 - 4,772,154 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000083718
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl37,782,572 - 7,861,497 (+)Ensembl
Rnor_6.0 Ensembl34,730,990 - 4,772,154 (+)Ensembl
RefSeq Acc Id: NM_144738   ⟹   NP_653339
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,180,751 - 28,259,673 (+)NCBI
mRatBN7.237,782,572 - 7,861,498 (+)NCBI
Rnor_6.032,182,957 - 2,261,879 (+)NCBI
Rnor_5.032,164,205 - 2,243,127 (+)NCBI
RGSC_v3.435,122,212 - 5,201,139 (+)RGD
Celera32,611,803 - 2,690,723 (+)RGD
Sequence:
RefSeq Acc Id: XM_039104252   ⟹   XP_038960180
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,180,670 - 28,250,842 (+)NCBI
mRatBN7.237,782,578 - 7,852,667 (+)NCBI
RefSeq Acc Id: XM_039104253   ⟹   XP_038960181
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,180,670 - 28,247,575 (+)NCBI
mRatBN7.237,782,605 - 7,849,404 (+)NCBI
RefSeq Acc Id: XM_039104254   ⟹   XP_038960182
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,180,670 - 28,243,870 (+)NCBI
mRatBN7.237,782,605 - 7,845,697 (+)NCBI
RefSeq Acc Id: XM_039104255   ⟹   XP_038960183
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,216,430 - 28,259,673 (+)NCBI
mRatBN7.237,818,255 - 7,861,504 (+)NCBI
RefSeq Acc Id: XM_039104256   ⟹   XP_038960184
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,220,777 - 28,259,673 (+)NCBI
mRatBN7.237,823,210 - 7,861,504 (+)NCBI
RefSeq Acc Id: XR_005501774
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,180,670 - 28,235,276 (+)NCBI
mRatBN7.237,782,605 - 7,837,102 (+)NCBI
RefSeq Acc Id: NP_653339   ⟸   NM_144738
- UniProtKB: Q8K3H9 (UniProtKB/Swiss-Prot),   Q5XIX2 (UniProtKB/Swiss-Prot),   Q5BK26 (UniProtKB/Swiss-Prot),   G3V745 (UniProtKB/TrEMBL),   A6JT00 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011633   ⟸   ENSRNOT00000011633
RefSeq Acc Id: XP_038960180   ⟸   XM_039104252
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038960181   ⟸   XM_039104253
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038960182   ⟸   XM_039104254
- Peptide Label: isoform X3
Cyclic nucleotide-binding   PNPLA

Name Modeler Protein Id AA Range Protein Structure
AF-Q5BK26-F1-model_v2 AlphaFold Q5BK26 1-1349 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 40 of 40 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-50490 BioCyc
Ensembl Genes ENSRNOG00000008190 Ensembl, ENTREZGENE
  ENSRNOG00000058862 Ensembl
Ensembl Transcript ENSRNOT00000011633 ENTREZGENE
  ENSRNOT00000141487 ENTREZGENE
Gene3D-CATH 2.60.120.10 UniProtKB/Swiss-Prot
  Cytosolic phospholipase A2 catalytic domain UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7132749 IMAGE-MGC_LOAD
  IMAGE:7321805 IMAGE-MGC_LOAD
InterPro Acyl_Trfase/lysoPLipase UniProtKB/Swiss-Prot
  cNMP-bd-like UniProtKB/Swiss-Prot
  cNMP-bd_dom UniProtKB/Swiss-Prot
  NTE UniProtKB/Swiss-Prot
  PNPLA_dom UniProtKB/Swiss-Prot
  RmlC-like_jellyroll UniProtKB/Swiss-Prot
KEGG Report rno:246246 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108975 IMAGE-MGC_LOAD
  MGC:93152 IMAGE-MGC_LOAD
NCBI Gene 246246 ENTREZGENE
PANTHER NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER UniProtKB/Swiss-Prot
  PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 7 UniProtKB/Swiss-Prot
Pfam cNMP_binding UniProtKB/Swiss-Prot
  Patatin UniProtKB/Swiss-Prot
PhenoGen Pnpla7 PhenoGen
PROSITE CNMP_BINDING_3 UniProtKB/Swiss-Prot
  PNPLA UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008190 RatGTEx
  ENSRNOG00000058862 RatGTEx
SMART cNMP UniProtKB/Swiss-Prot
Superfamily-SCOP SSF51206 UniProtKB/Swiss-Prot
  SSF52151 UniProtKB/Swiss-Prot
UniProt A0A8I6AQ73_RAT UniProtKB/TrEMBL
  A0A8I6AUA6_RAT UniProtKB/TrEMBL
  A6JT00 ENTREZGENE, UniProtKB/TrEMBL
  G3V745 ENTREZGENE, UniProtKB/TrEMBL
  PLPL7_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q5XIX2 ENTREZGENE
  Q8K3H9 ENTREZGENE
UniProt Secondary Q5XIX2 UniProtKB/Swiss-Prot
  Q8K3H9 UniProtKB/Swiss-Prot
1 to 40 of 40 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Pnpla7  patatin-like phospholipase domain containing 7  LOC100911867  patatin-like phospholipase domain-containing protein 7-like  Data merged from RGD:6490002 737654 PROVISIONAL
2012-07-05 LOC100911867  patatin-like phospholipase domain-containing protein 7-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-02-25 Pnpla7  patatin-like phospholipase domain containing 7  Ntel1  neuropathy target esterase like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Ntel1  neuropathy target esterase like 1  Ntel  NTE-related protein  Symbol and Name updated 1299863 APPROVED
2005-09-30 Ntel        Symbol and Name status set to provisional 70820 PROVISIONAL