Pnpla7 (patatin like phospholipase domain containing 7) - Rat Genome Database

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Gene: Pnpla7 (patatin like phospholipase domain containing 7) Chinchilla lanigera
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Symbol: Pnpla7
Name: patatin like phospholipase domain containing 7
RGD ID: 8901511
Description: ENCODES a protein that exhibits lysophospholipase activity (ortholog); INVOLVED IN phosphatidylcholine catabolic process (ortholog); ASSOCIATED WITH Adams-Oliver Syndrome 5 (ortholog); autosomal dominant intellectual developmental disorder 8 (ortholog); Autosomal Recessive Peripheral Neuropathy with or without Impaired Intellectual Development (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); lipid droplet (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: patatin-like phospholipase domain containing 7; patatin-like phospholipase domain-containing protein 7
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555135,376,699 - 5,434,581 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555135,376,690 - 5,436,095 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pnpla7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555135,376,699 - 5,434,581 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555135,376,690 - 5,436,095 (-)NCBIChiLan1.0ChiLan1.0
PNPLA7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389137,459,952 - 137,550,402 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9137,459,952 - 137,550,402 (-)EnsemblGRCh38hg38GRCh38
GRCh379140,354,404 - 140,444,854 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369139,474,226 - 139,564,807 (-)NCBINCBI36Build 36hg18NCBI36
Build 349137,630,241 - 137,720,673NCBI
Celera9110,879,193 - 110,969,453 (-)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9109,818,540 - 109,909,455 (-)NCBIHuRef
CHM1_19140,501,929 - 140,594,079 (-)NCBICHM1_1
T2T-CHM13v2.09149,710,086 - 149,803,830 (-)NCBIT2T-CHM13v2.0
Pnpla7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39224,865,235 - 24,944,084 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl224,866,045 - 24,944,069 (+)EnsemblGRCm39 Ensembl
GRCm38224,975,990 - 25,054,072 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl224,976,033 - 25,054,057 (+)EnsemblGRCm38mm10GRCm38
MGSCv37224,831,553 - 24,909,592 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36224,798,097 - 24,876,064 (+)NCBIMGSCv36mm8
Celera224,699,962 - 24,781,158 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map216.88NCBI
Pnpla7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8328,180,670 - 28,259,673 (+)NCBIGRCr8
mRatBN7.237,782,572 - 7,861,504 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl37,782,572 - 7,861,497 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx310,887,331 - 10,966,646 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0319,473,561 - 19,552,873 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0317,663,405 - 17,742,723 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.032,182,191 - 2,261,890 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl32,182,957 - 2,261,878 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl34,730,990 - 4,772,154 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.032,164,205 - 2,243,127 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.435,122,212 - 5,201,139 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.135,163,825 - 5,201,138 (+)NCBI
Celera32,611,803 - 2,690,723 (+)NCBICelera
Cytogenetic Map3p13NCBI
PNPLA7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2111,826,805 - 1,928,145 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan191,830,080 - 1,930,479 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09108,531,917 - 108,631,119 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19137,496,924 - 137,593,154 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9137,496,924 - 137,593,154 (-)Ensemblpanpan1.1panPan2
PNPLA7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1948,221,754 - 48,286,352 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl948,221,514 - 48,286,352 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha947,408,962 - 47,473,587 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0949,083,836 - 49,148,496 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl949,083,916 - 49,148,495 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1947,860,228 - 47,924,866 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0948,159,209 - 48,223,845 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0948,205,678 - 48,270,340 (+)NCBIUU_Cfam_GSD_1.0
Pnpla7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947202,769,065 - 202,840,510 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936669535,796 - 605,710 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936669535,104 - 605,993 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PNPLA7
(Sus scrofa - pig)		 No map positions available.
PNPLA7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112655,723 - 734,315 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660584,614,234 - 4,694,034 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pnpla7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624760521,145 - 575,431 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000008656   ⟹   ENSCLAP00000008529
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555135,376,699 - 5,434,581 (-)Ensembl
RefSeq Acc Id: XM_005408619   ⟹   XP_005408676
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555135,376,690 - 5,436,049 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005408620   ⟹   XP_005408677
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555135,376,690 - 5,436,095 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005408621   ⟹   XP_005408678
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555135,376,690 - 5,435,271 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013506659   ⟹   XP_013362113
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555135,376,690 - 5,435,272 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013506660   ⟹   XP_013362114
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555135,376,690 - 5,435,271 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005408677   ⟸   XM_005408620
- Peptide Label: isoform X1
- UniProtKB: A0A8C2V0M9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005408676   ⟸   XM_005408619
- Peptide Label: isoform X1
- UniProtKB: A0A8C2V0M9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005408678   ⟸   XM_005408621
- Peptide Label: isoform X3
- UniProtKB: A0A8C2V0M9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013362113   ⟸   XM_013506659
- Peptide Label: isoform X2
- UniProtKB: A0A8C2V0M9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013362114   ⟸   XM_013506660
- Peptide Label: isoform X4
- UniProtKB: A0A8C2V0M9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000008529   ⟸   ENSCLAT00000008656
Protein Domains
Cyclic nucleotide-binding   PNPLA


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005965 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000008656 ENTREZGENE
  ENSCLAT00000008656.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.10 UniProtKB/TrEMBL
  Cytosolic phospholipase A2 catalytic domain UniProtKB/TrEMBL
InterPro Acyl_Trfase/lysoPLipase UniProtKB/TrEMBL
  cNMP-bd-like UniProtKB/TrEMBL
  cNMP-bd_dom UniProtKB/TrEMBL
  NTE UniProtKB/TrEMBL
  PNPLA_dom UniProtKB/TrEMBL
  RmlC-like_jellyroll UniProtKB/TrEMBL
NCBI Gene Pnpla7 ENTREZGENE
PANTHER NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER UniProtKB/TrEMBL
  PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 7 UniProtKB/TrEMBL
Pfam cNMP_binding UniProtKB/TrEMBL
  Patatin UniProtKB/TrEMBL
PROSITE CNMP_BINDING_3 UniProtKB/TrEMBL
  PNPLA UniProtKB/TrEMBL
SMART cNMP UniProtKB/TrEMBL
Superfamily-SCOP SSF51206 UniProtKB/TrEMBL
  SSF52151 UniProtKB/TrEMBL
UniProt A0A8C2V0M9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Pnpla7  patatin like phospholipase domain containing 7    patatin-like phospholipase domain containing 7  Symbol and/or name change 5135510 APPROVED