Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | HECA (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of HECA mRNA | CTD | PMID:22079256 | (1->4)-beta-D-glucan | multiple interactions | ISO | Heca (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of HECA mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | decreases expression | ISO | Heca (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of HECA mRNA | CTD | PMID:22206623 | 17beta-estradiol | decreases expression | ISO | HECA (Homo sapiens) | 6480464 | Estradiol results in decreased expression of HECA mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Heca (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of HECA mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of HECA mRNA | CTD | PMID:34747641 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of HECA mRNA | CTD | PMID:24780913 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of HECA mRNA | CTD | PMID:31881176 | aflatoxin B1 | increases expression | ISO | HECA (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of HECA mRNA | CTD | PMID:21641981 | all-trans-retinoic acid | increases expression | ISO | HECA (Homo sapiens) | 6480464 | Tretinoin results in increased expression of HECA mRNA | CTD | PMID:23724009 | aristolochic acid A | decreases expression | ISO | HECA (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of HECA mRNA | CTD | PMID:33212167 | arsenous acid | increases expression | ISO | HECA (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of HECA mRNA | CTD | PMID:20458559 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of HECA mRNA | CTD | PMID:21839799 | benzo[a]pyrene | affects methylation | ISO | HECA (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of HECA promoter | CTD | PMID:27901495 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of HECA mRNA | CTD | PMID:25181051 | cadmium dichloride | increases expression | ISO | Heca (Mus musculus) | 6480464 | Cadmium Chloride results in increased expression of HECA mRNA | CTD | PMID:20883709 | cadmium dichloride | increases methylation | EXP | | 6480464 | Cadmium Chloride results in increased methylation of HECA promoter | CTD | PMID:22457795 | caffeine | increases expression | EXP | | 6480464 | Caffeine results in increased expression of HECA mRNA | CTD | PMID:20864626 | carbon nanotube | decreases expression | ISO | Heca (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | copper(II) sulfate | increases expression | ISO | HECA (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of HECA mRNA | CTD | PMID:19549813 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of HECA mRNA | CTD | PMID:26577399 | cyclosporin A | increases expression | ISO | HECA (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of HECA mRNA | CTD | PMID:20106945 | diarsenic trioxide | increases expression | ISO | HECA (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of HECA mRNA | CTD | PMID:20458559 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of HECA mRNA | CTD | PMID:21266533 | dibutyl phthalate | increases expression | ISO | Heca (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of HECA mRNA | CTD | PMID:21266533 | disodium selenite | increases expression | ISO | HECA (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of HECA mRNA | CTD | PMID:18175754 | ethanol | affects expression | ISO | Heca (Mus musculus) | 6480464 | Ethanol affects the expression of HECA mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | increases expression | ISO | HECA (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of HECA mRNA | CTD | PMID:23649840 | formaldehyde | increases expression | ISO | HECA (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of HECA mRNA | CTD | PMID:23649840 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of HECA mRNA | CTD | PMID:22061828 | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of HECA mRNA | CTD | PMID:24136188 | isoprenaline | increases expression | ISO | Heca (Mus musculus) | 6480464 | Isoproterenol results in increased expression of HECA mRNA | CTD | PMID:20003209 | menadione | affects expression | ISO | HECA (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of HECA mRNA | CTD | PMID:20044591 | methoxyacetic acid | increases expression | EXP | | 6480464 | methoxyacetic acid results in increased expression of HECA mRNA | CTD | PMID:20864626 | methyl methanesulfonate | increases expression | ISO | HECA (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of HECA mRNA | CTD | PMID:23649840 | methylmercury chloride | increases expression | EXP | | 6480464 | methylmercuric chloride results in increased expression of HECA mRNA | CTD | PMID:20864626 | Monobutylphthalate | increases expression | EXP | | 6480464 | monobutyl phthalate results in increased expression of HECA mRNA | CTD | PMID:20864626 | ozone | multiple interactions | ISO | HECA (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of HECA mRNA | CTD | PMID:35430440 | paracetamol | increases expression | ISO | HECA (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of HECA mRNA | CTD | PMID:29067470 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | HECA (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of HECA mRNA | CTD | PMID:27153767 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Heca (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of HECA mRNA | CTD | PMID:36331819 | phenobarbital | affects expression | ISO | HECA (Homo sapiens) | 6480464 | Phenobarbital affects the expression of HECA mRNA | CTD | PMID:19159669 | phenobarbital | affects expression | ISO | Heca (Mus musculus) | 6480464 | Phenobarbital affects the expression of HECA mRNA | CTD | PMID:23091169 | pirinixic acid | multiple interactions | ISO | HECA (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of HECA mRNA | CTD | PMID:19710929 | pirinixic acid | decreases expression | ISO | Heca (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of HECA mRNA | CTD | PMID:20813756 | potassium chromate | multiple interactions | ISO | HECA (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of HECA mRNA | CTD | PMID:22079256 | potassium chromate | increases expression | ISO | HECA (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of HECA mRNA | CTD | PMID:22079256 | propiconazole | decreases expression | ISO | Heca (Mus musculus) | 6480464 | propiconazole results in decreased expression of HECA mRNA | CTD | PMID:21278054 | silicon dioxide | decreases expression | ISO | HECA (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of HECA mRNA | CTD | PMID:25895662 | silver atom | decreases expression | ISO | Heca (Mus musculus) | 6480464 | Silver results in decreased expression of HECA mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | ISO | Heca (Mus musculus) | 6480464 | Silver results in decreased expression of HECA mRNA | CTD | PMID:27131904 | sodium arsenite | increases expression | ISO | Heca (Mus musculus) | 6480464 | sodium arsenite results in increased expression of HECA mRNA | CTD | PMID:20883709 | sunitinib | increases expression | ISO | HECA (Homo sapiens) | 6480464 | Sunitinib results in increased expression of HECA mRNA | CTD | PMID:31533062 | testosterone | decreases expression | ISO | HECA (Homo sapiens) | 6480464 | Testosterone results in decreased expression of HECA mRNA | CTD | PMID:33359661 | tetrachloroethene | increases expression | ISO | Heca (Mus musculus) | 6480464 | Tetrachloroethylene results in increased expression of HECA mRNA | CTD | PMID:28973375 | tetrachloromethane | increases expression | ISO | Heca (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of HECA mRNA | CTD | PMID:27339419 | trichostatin A | increases expression | ISO | HECA (Homo sapiens) | 6480464 | trichostatin A results in increased expression of HECA mRNA | CTD | PMID:24935251 | troglitazone | decreases expression | ISO | Heca (Mus musculus) | 6480464 | troglitazone results in decreased expression of HECA mRNA | CTD | PMID:28973697 | urethane | increases expression | ISO | HECA (Homo sapiens) | 6480464 | Urethane results in increased expression of HECA mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | HECA (Homo sapiens) | 6480464 | Valproic Acid affects the expression of HECA mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | HECA (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of HECA mRNA | CTD | PMID:19101580 more ... | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of HECA mRNA | CTD | PMID:19015723 | |