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Gene: Prodh1 (proline dehydrogenase 1) Rattus norvegicus
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Symbol: Prodh1
Name: proline dehydrogenase 1
Description: Exhibits amino acid binding activity and proline dehydrogenase activity. Predicted to be involved in positive regulation of cell death and proline catabolic process to glutamate. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and schizophrenia 4. Orthologous to human PRODH (proline dehydrogenase 1); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; guanidinoacetate methyltransferase deficiency pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC680409; Prodh; Prodh_mapped; proline dehydrogenase; proline dehydrogenase (mapped); proline dehydrogenase (oxidase) 1; proline dehydrogenase (proline oxidase); proline dehydrogenase 1, mitochondrial; proline dehydrogenase, mitochondrial; similar to Proline oxidase, mitochondrial precursor (Proline dehydrogenase)
Orthologs:
Homo sapiens (human) : PRODH (proline dehydrogenase 1)  HGNC  Alliance
Mus musculus (house mouse) : Prodh (proline dehydrogenase)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : PRODH (proline dehydrogenase 1)
Canis lupus familiaris (dog) : LOC477562 (proline dehydrogenase 1, mitochondrial)
Sus scrofa (pig) : LOC110256626 (proline dehydrogenase 1, mitochondrial)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01187,058,478 - 87,075,785 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01190,150,469 - 90,167,638 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41184,905,060 - 84,922,229 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1181,685,816 - 81,702,985 (+)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Prodh1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1590932
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.