Snapin (SNAP-associated protein) - Rat Genome Database

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Gene: Snapin (SNAP-associated protein) Rattus norvegicus
Analyze
Symbol: Snapin
Name: SNAP-associated protein
RGD ID: 1560377
Description: Predicted to enable SNARE binding activity. Predicted to be involved in several processes, including anterograde synaptic vesicle transport; endosome to lysosome transport; and synaptic vesicle exocytosis. Predicted to act upstream of or within several processes, including lysosomal lumen acidification; terminal button organization; and vesicle organization. Located in secretory granule. Is active in glutamatergic synapse and synaptic vesicle. Orthologous to human SNAPIN (SNAP associated protein); INTERACTS WITH acetamide; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: biogenesis of lysosome-related organelles complex 1 subunit 7; BLOC-1 subunit 7; MGC112927; Snapap; SNARE associated protein snapin; SNARE-associated protein Snapin; synaptosomal-associated protein 25-binding protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82178,269,157 - 178,271,746 (-)NCBIGRCr8
mRatBN7.22175,971,575 - 175,974,164 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2175,971,257 - 175,974,231 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2183,111,652 - 183,114,246 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02181,133,916 - 181,136,510 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02175,734,232 - 175,736,824 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02189,878,159 - 189,880,743 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2189,878,168 - 189,880,743 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02209,309,032 - 209,311,616 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42182,762,310 - 182,764,481 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2169,907,172 - 169,909,756 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SnapinRatCOVID-19  ISOSNAPIN (Homo sapiens)9068941mRNA:increased expression:peripheral blood mononuclear cell (human)RGDPMID:32228226 and REF_RGD_ID:28912744
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SnapinRatgastrointestinal stromal tumor  ISOSNAPIN (Homo sapiens)8554872ClinVar Annotator: match by term: Gastrointestinal stromal tumorClinVarPMID:28492532
SnapinRatimmunodeficiency 42  ISOSNAPIN (Homo sapiens)8554872ClinVar Annotator: match by term: Autosomal recessive mendelian susceptibility to mycobacterial diseases due to complete RORgamma receptor deficiencyClinVarPMID:28492532
SnapinRatMHC class II deficiency  ISOSNAPIN (Homo sapiens)8554872ClinVar Annotator: match by term: MHC class II deficiencyClinVarPMID:28492532
SnapinRatparathyroid carcinoma  ISOSNAPIN (Homo sapiens)8554872ClinVar Annotator: match by term: Parathyroid carcinomaClinVarPMID:28492532
SnapinRatsevere congenital neutropenia 3  ISOSNAPIN (Homo sapiens)8554872ClinVar Annotator: match by term: Kostmann syndromeClinVarPMID:28492532
SnapinRatsevere congenital neutropenia 5  ISOSNAPIN (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital neutropenia-myelofibrosis-nephromegaly syndromeClinVarPMID:28492532

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SnapinRat(-)-epigallocatechin 3-gallate multiple interactionsISOSNAPIN (Homo sapiens)6480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SNAPIN mRNACTDPMID:22079256
SnapinRat(1->4)-beta-D-glucan multiple interactionsISOSnapin (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SNAPIN mRNACTDPMID:36331819
SnapinRat1,2-dimethylhydrazine multiple interactionsISOSnapin (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SNAPIN mRNACTDPMID:22206623
SnapinRat17beta-estradiol decreases expressionISOSNAPIN (Homo sapiens)6480464Estradiol results in decreased expression of SNAPIN mRNACTDPMID:23019147
SnapinRat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOSnapin (Mus musculus)6480464[2 more ...CTDPMID:25510870
SnapinRat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISOSnapin (Mus musculus)6480464[2 more ...CTDPMID:25510870
SnapinRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOSnapin (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of SNAPIN mRNACTDPMID:21570461
SnapinRat2-hydroxypropanoic acid decreases expressionISOSNAPIN (Homo sapiens)6480464Lactic Acid results in decreased expression of SNAPIN mRNACTDPMID:30851411
SnapinRat3-methylcholanthrene multiple interactionsISOSNAPIN (Homo sapiens)6480464Methylcholanthrene promotes the reaction [AHR protein binds to SNAPIN promoter]CTDPMID:20348232
SnapinRat4,4'-sulfonyldiphenol decreases expressionISOSnapin (Mus musculus)6480464bisphenol S results in decreased expression of SNAPIN mRNACTDPMID:37611474
SnapinRatacetamide decreases expressionEXP 6480464acetamide results in decreased expression of SNAPIN mRNACTDPMID:31881176
SnapinRatacrylamide decreases expressionISOSnapin (Mus musculus)6480464Acrylamide results in decreased expression of SNAPIN mRNACTDPMID:29261810
SnapinRataristolochic acid A decreases expressionISOSNAPIN (Homo sapiens)6480464aristolochic acid I results in decreased expression of SNAPIN mRNACTDPMID:33212167
SnapinRatAroclor 1254 decreases expressionISOSnapin (Mus musculus)6480464Chlorodiphenyl (54% Chlorine) results in decreased expression of SNAPIN mRNACTDPMID:23650126
SnapinRatbis(2-ethylhexyl) phthalate increases expressionISOSnapin (Mus musculus)6480464Diethylhexyl Phthalate results in increased expression of SNAPIN mRNACTDPMID:33754040
SnapinRatbisphenol A affects expressionEXP 6480464bisphenol A affects the expression of SNAPIN mRNACTDPMID:25181051
SnapinRatbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of SNAPIN mRNACTDPMID:34947998
SnapinRatcadmium dichloride decreases expressionEXP 6480464Cadmium Chloride results in decreased expression of SNAPIN mRNACTDPMID:33453195
SnapinRatcadmium dichloride decreases expressionISOSNAPIN (Homo sapiens)6480464Cadmium Chloride results in decreased expression of SNAPIN mRNACTDPMID:38568856
SnapinRatcaffeine affects phosphorylationISOSNAPIN (Homo sapiens)6480464Caffeine affects the phosphorylation of SNAPIN proteinCTDPMID:35688186

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Biological Process
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SnapinRatanterograde axonal transport involved_inISSUniProtKB:Q9Z2661600115GO_REF:0000024UniProtGO_REF:0000024
SnapinRatanterograde axonal transport involved_inISOSnapin (Mus musculus)1624291 PMID:21998198RGDPMID:21998198
SnapinRatanterograde synaptic vesicle transport involved_inISSUniProtKB:Q9Z2661600115GO_REF:0000024UniProtGO_REF:0000024
SnapinRatanterograde synaptic vesicle transport involved_inISOSnapin (Mus musculus)1624291 PMID:21998198RGDPMID:21998198
SnapinRatautophagosome maturation acts_upstream_of_or_withinISOSnapin (Mus musculus)1624291MGI:3608768 PMID:20920792 and PMID:22797916RGDPMID:20920792 and PMID:22797916
SnapinRatchemical synaptic transmission acts_upstream_of_or_withinISOSnapin (Mus musculus)1624291MGI:3608768 PMID:19217378RGDPMID:19217378
SnapinRatendosome to lysosome transport acts_upstream_of_or_withinISOSNAPIN (Homo sapiens)1624291UniProtKB:Q6ZNE5 and PMID:22797916RGDPMID:22797916
SnapinRatendosome to lysosome transport acts_upstream_of_or_withinIEAUniProtKB:O95295 and ensembl:ENSP000003576741600115GO_REF:0000107EnsemblGO_REF:0000107
SnapinRatendosome to lysosome transport involved_inIBAPANTHER:PTN001582645 and UniProtKB:O952951600115GO_REF:0000033GO_CentralGO_REF:0000033
SnapinRatestablishment of vesicle localization acts_upstream_of_or_withinISOSnapin (Mus musculus)1624291MGI:3608768 PMID:20920792RGDPMID:20920792
SnapinRatexocytosis involved_inIEAUniProtKB-KW:KW-02681600115GO_REF:0000043UniProtGO_REF:0000043
SnapinRatintracellular protein transport involved_inIEAInterPro:IPR0172461600115GO_REF:0000002InterProGO_REF:0000002
SnapinRatlate endosome to lysosome transport acts_upstream_of_or_withinISOSnapin (Mus musculus)1624291MGI:3608768 PMID:20920792RGDPMID:20920792
SnapinRatlysosomal lumen acidification acts_upstream_of_or_withinISOSnapin (Mus musculus)1624291MGI:3608768 PMID:20920792RGDPMID:20920792
SnapinRatlysosome localization involved_inISSUniProtKB:O952951600115GO_REF:0000024UniProtGO_REF:0000024
SnapinRatlysosome localization involved_inIBAPANTHER:PTN001582645 and UniProtKB:O952951600115GO_REF:0000033GO_CentralGO_REF:0000033
SnapinRatlysosome localization involved_inISOSNAPIN (Homo sapiens)1624291 PMID:25898167RGDPMID:25898167
SnapinRatlysosome localization involved_inIEAUniProtKB:O95295 and ensembl:ENSP000003576741600115GO_REF:0000107EnsemblGO_REF:0000107
SnapinRatlysosome organization involved_inIBAMGI:1333745 and PANTHER:PTN0015826451600115GO_REF:0000033GO_CentralGO_REF:0000033
SnapinRatlysosome organization acts_upstream_of_or_withinISOSnapin (Mus musculus)1624291MGI:3608768 PMID:20920792RGDPMID:20920792
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Cellular Component
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SnapinRatacrosomal vesicle located_inISOSnapin (Mus musculus)1624291 PMID:31146259RGDPMID:31146259
SnapinRataxon cytoplasm located_inIEAGO:00080901600115GO_REF:0000108GOCGO_REF:0000108
SnapinRataxon cytoplasm located_inIEAGO:00080891600115GO_REF:0000108GOCGO_REF:0000108
SnapinRatBLOC-1 complex part_ofISSUniProtKB:O952951600115GO_REF:0000024UniProtGO_REF:0000024
SnapinRatBLOC-1 complex part_ofIEAInterPro:IPR0172461600115GO_REF:0000002InterProGO_REF:0000002
SnapinRatBLOC-1 complex part_ofISOSnapin (Mus musculus)1624291 PMID:15102850RGDPMID:15102850
SnapinRatBLOC-1 complex part_ofIBAMGI:1333745 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
SnapinRatBLOC-1 complex part_ofISOSNAPIN (Homo sapiens)1624291 PMID:15102850 and PMID:22203680RGDPMID:15102850 and PMID:22203680
SnapinRatBLOC-1 complex part_ofIEAUniProtKB:O95295 and ensembl:ENSP000003576741600115GO_REF:0000107EnsemblGO_REF:0000107
SnapinRatBORC complex part_ofISSUniProtKB:O952951600115GO_REF:0000024UniProtGO_REF:0000024
SnapinRatBORC complex part_ofIEAUniProtKB:O95295 and ensembl:ENSP000003576741600115GO_REF:0000107EnsemblGO_REF:0000107
SnapinRatBORC complex part_ofISOSNAPIN (Homo sapiens)1624291 PMID:25898167RGDPMID:25898167
SnapinRatcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
SnapinRatcytoplasmic vesicle located_inIEAARBA:ARBA000271901600115GO_REF:0000117UniProtGO_REF:0000117
SnapinRatcytoplasmic vesicle located_inISOSnapin (Mus musculus)1624291 PMID:31146259RGDPMID:31146259
SnapinRatcytoplasmic vesicle located_inIEAUniProtKB-KW:KW-09681600115GO_REF:0000043UniProtGO_REF:0000043
SnapinRatcytosol located_inISOSnapin (Mus musculus)1624291 PMID:15102850RGDPMID:15102850
SnapinRatcytosol located_inIEAUniProtKB-SubCell:SL-00911600115GO_REF:0000044UniProtGO_REF:0000044
SnapinRatglutamatergic synapse is_active_inIDA 405650383PMID:20696250SynGO 
SnapinRatGolgi apparatus located_inIEAUniProtKB-KW:KW-03331600115GO_REF:0000043UniProtGO_REF:0000043
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Molecular Function

  


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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The dystonia-associated protein torsinA modulates synaptic vesicle recycling. Granata A, etal., J Biol Chem. 2008 Mar 21;283(12):7568-79. doi: 10.1074/jbc.M704097200. Epub 2007 Dec 31.
3. Snapin: a SNARE-associated protein implicated in synaptic transmission. Ilardi JM, etal., Nat Neurosci. 1999 Feb;2(2):119-24. doi: 10.1038/5673.
4. Clusterin interacts with SCLIP (SCG10-like protein) and promotes neurite outgrowth of PC12 cells. Kang SW, etal., Exp Cell Res. 2005 Oct 1;309(2):305-15.
5. The TRPM7 ion channel functions in cholinergic synaptic vesicles and affects transmitter release. Krapivinsky G, etal., Neuron. 2006 Nov 9;52(3):485-96.
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. EBAG9 adds a new layer of control on large dense-core vesicle exocytosis via interaction with Snapin. Ruder C, etal., Mol Biol Cell. 2005 Mar;16(3):1245-57. Epub 2005 Jan 5.
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10. EHD1 is a synaptic protein that modulates exocytosis through binding to snapin. Wei S, etal., Mol Cell Neurosci. 2010 Dec;45(4):418-29. doi: 10.1016/j.mcn.2010.07.014. Epub 2010 Aug 6.
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PMID:11283605   PMID:12877659   PMID:15057822   PMID:15084593   PMID:15102850   PMID:16120643   PMID:16723744   PMID:17101137   PMID:17684020   PMID:17702749   PMID:18480566   PMID:19168546  
PMID:19217378   PMID:20920792   PMID:21102408   PMID:21986494   PMID:21998198   PMID:22203680   PMID:22797916   PMID:23949442   PMID:25898167   PMID:26946359  



Snapin
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82178,269,157 - 178,271,746 (-)NCBIGRCr8
mRatBN7.22175,971,575 - 175,974,164 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2175,971,257 - 175,974,231 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2183,111,652 - 183,114,246 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02181,133,916 - 181,136,510 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02175,734,232 - 175,736,824 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02189,878,159 - 189,880,743 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2189,878,168 - 189,880,743 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02209,309,032 - 209,311,616 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42182,762,310 - 182,764,481 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2169,907,172 - 169,909,756 (-)NCBICelera
Cytogenetic Map2q34NCBI
SNAPIN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381153,658,654 - 153,661,852 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1153,658,703 - 153,661,852 (+)EnsemblGRCh38hg38GRCh38
GRCh371153,631,130 - 153,634,328 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361151,897,824 - 151,900,930 (+)NCBINCBI36Build 36hg18NCBI36
Build 341150,444,272 - 150,447,378NCBI
Celera1126,702,324 - 126,705,505 (+)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1124,994,466 - 124,997,664 (+)NCBIHuRef
CHM1_11155,027,119 - 155,030,317 (+)NCBICHM1_1
T2T-CHM13v2.01152,795,919 - 152,799,117 (+)NCBIT2T-CHM13v2.0
Snapin
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39390,395,333 - 90,398,320 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl390,395,333 - 90,398,340 (-)EnsemblGRCm39 Ensembl
GRCm38390,488,026 - 90,491,013 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl390,488,026 - 90,491,033 (-)EnsemblGRCm38mm10GRCm38
MGSCv37390,291,948 - 90,294,935 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36390,573,961 - 90,576,931 (-)NCBIMGSCv36mm8
Celera390,525,872 - 90,528,858 (-)NCBICelera
Cytogenetic Map3F1NCBI
cM Map339.24NCBI
Snapin
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955545306,546 - 308,229 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955545306,546 - 308,229 (+)NCBIChiLan1.0ChiLan1.0
SNAPIN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2196,170,659 - 96,173,840 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1195,903,764 - 95,909,036 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01129,014,668 - 129,018,428 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11132,644,319 - 132,647,095 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1132,644,320 - 132,647,095 (+)Ensemblpanpan1.1panPan2
SNAPIN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1743,410,554 - 43,411,929 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl743,410,998 - 43,412,323 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha742,903,507 - 42,904,962 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0743,360,183 - 43,361,638 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl743,358,154 - 43,362,026 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1743,062,261 - 43,063,711 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0743,115,755 - 43,117,214 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0743,399,406 - 43,400,865 (-)NCBIUU_Cfam_GSD_1.0
Snapin
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505824,433,043 - 24,436,084 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365803,462,987 - 3,464,214 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365803,449,585 - 3,464,709 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SNAPIN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl495,984,358 - 95,989,474 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1495,987,524 - 95,989,527 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24104,880,697 - 104,882,699 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SNAPIN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12010,147,577 - 10,150,721 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2010,148,099 - 10,150,641 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660389,524,858 - 9,528,002 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Snapin
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248853,490,321 - 3,491,946 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248853,490,321 - 3,491,963 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Snapin
9 total Variants

Predicted Target Of
Summary Value
Count of predictions:134
Count of miRNA genes:118
Interacting mature miRNAs:123
Transcripts:ENSRNOT00000018830
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


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The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)218960362228801039Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
152025245Scl81Serum cholesterol level QTL 813.49blood cholesterol amount (VT:0000180)2122609194206936711Rat
70162Bp63Blood pressure QTL 635.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat

1 to 10 of 65 rows
RH134098  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22175,971,778 - 175,971,957 (+)MAPPERmRatBN7.2
Rnor_6.02189,878,363 - 189,878,541NCBIRnor6.0
Rnor_5.02209,309,236 - 209,309,414UniSTSRnor5.0
RGSC_v3.42182,762,514 - 182,762,692UniSTSRGSC3.4
Celera2169,907,376 - 169,907,554UniSTS
RH 3.4 Map21163.1UniSTS
Cytogenetic Map2q34UniSTS
RH141438  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22175,972,384 - 175,972,592 (+)MAPPERmRatBN7.2
Rnor_6.02189,878,969 - 189,879,176NCBIRnor6.0
Rnor_5.02209,309,842 - 209,310,049UniSTSRnor5.0
RGSC_v3.42182,763,120 - 182,763,327UniSTSRGSC3.4
Celera2169,907,982 - 169,908,189UniSTS
RH 3.4 Map21162.4UniSTS
Cytogenetic Map2q34UniSTS
AA799709  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map21168.21UniSTS
Cytogenetic Map2q34UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000018830   ⟹   ENSRNOP00000018830
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2175,971,257 - 175,974,231 (-)Ensembl
Rnor_6.0 Ensembl2189,878,168 - 189,880,743 (-)Ensembl
RefSeq Acc Id: NM_001025648   ⟹   NP_001020819
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82178,269,157 - 178,271,746 (-)NCBI
mRatBN7.22175,971,575 - 175,974,164 (-)NCBI
Rnor_6.02189,878,159 - 189,880,330 (-)NCBI
Rnor_5.02209,309,032 - 209,311,616 (-)NCBI
RGSC_v3.42182,762,310 - 182,764,481 (-)RGD
Celera2169,907,172 - 169,909,343 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001170576   ⟹   NP_001164047
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82178,269,157 - 178,271,746 (-)NCBI
mRatBN7.22175,971,575 - 175,974,164 (-)NCBI
Rnor_6.02189,878,159 - 189,880,743 (-)NCBI
Rnor_5.02209,309,032 - 209,311,616 (-)NCBI
Celera2169,907,172 - 169,909,756 (-)NCBI
Sequence:
Protein RefSeqs NP_001020819 (Get FASTA)   NCBI Sequence Viewer  
  NP_001164047 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH98864 (Get FASTA)   NCBI Sequence Viewer  
  EDM00562 (Get FASTA)   NCBI Sequence Viewer  
  EDM00563 (Get FASTA)   NCBI Sequence Viewer  
  EDM00564 (Get FASTA)   NCBI Sequence Viewer  
  P60192 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001020819   ⟸   NM_001025648
- Peptide Label: isoform 2
- UniProtKB: Q4KM25 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001164047   ⟸   NM_001170576
- Peptide Label: isoform 1
- UniProtKB: P60192 (UniProtKB/Swiss-Prot),   A6J6M5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018830   ⟸   ENSRNOT00000018830

Name Modeler Protein Id AA Range Protein Structure
AF-P60192-F1-model_v2 AlphaFold P60192 1-136 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13691503
Promoter ID:EPDNEW_R2028
Type:initiation region
Name:Snapin_1
Description:SNAP-associated protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02189,880,737 - 189,880,797EPDNEW


1 to 19 of 19 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-52340 BioCyc
Ensembl Genes ENSRNOG00000013356 Ensembl
IMAGE_CLONE IMAGE:7380523 IMAGE-MGC_LOAD
InterPro Snapin UniProtKB/Swiss-Prot
  Snapin/Pallidin/Snn1 UniProtKB/Swiss-Prot
KEGG Report rno:295217 UniProtKB/Swiss-Prot
MGC_CLONE MGC:112927 IMAGE-MGC_LOAD
NCBI Gene 295217 ENTREZGENE
PANTHER PTHR31305 UniProtKB/Swiss-Prot
  SNARE-ASSOCIATED PROTEIN SNAPIN UniProtKB/Swiss-Prot
Pfam Snapin_Pallidin UniProtKB/Swiss-Prot
PhenoGen Snapin PhenoGen
PIRSF Snapin UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000013356 RatGTEx
UniProt A0A8L2UJD2_RAT UniProtKB/TrEMBL
  A6J6M5 ENTREZGENE, UniProtKB/TrEMBL
  P60192 ENTREZGENE
  Q4KM25 ENTREZGENE, UniProtKB/TrEMBL
  SNAPN_RAT UniProtKB/Swiss-Prot
1 to 19 of 19 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-02 Snapin  SNAP-associated protein  Snapap  SNAP-associated protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Snapap  SNAP-associated protein      Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 Snapap  SNAP-associated protein      Symbol and Name status set to provisional 70820 PROVISIONAL