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Gene: Capn10 (calpain 10) Rattus norvegicus
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Symbol: Capn10
Name: calpain 10
Description: Exhibits SNARE binding activity; calcium-dependent cysteine-type endopeptidase activity; and cytoskeletal protein binding activity. Involved in several processes, including actin cytoskeleton reorganization; aging; and autophagy of mitochondrion. Localizes to several cellular components, including the cytoplasm; cytoskeleton; and plasma membrane. Used to study type 2 diabetes mellitus. Biomarker of type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in obesity; pancreatic cancer; polycystic ovary syndrome; and type 2 diabetes mellitus. Orthologous to human CAPN10 (calpain 10); INTERACTS WITH 2,4-dinitrotoluene; acrylamide; arsenite(3-).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: calcium-activated neutral proteinase 10; calpain-10; CANP 10; MGC93346
Orthologs:
Homo sapiens (human) : CAPN10 (calpain 10)  HGNC  Alliance
Mus musculus (house mouse) : Capn10 (calpain 10)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Capn10 (calpain 10)
Pan paniscus (bonobo/pygmy chimpanzee) : CAPN10 (calpain 10)
Canis lupus familiaris (dog) : CAPN10 (calpain 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Capn10 (calpain 10)
Sus scrofa (pig) : CAPN10 (calpain 10)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.09100,104,000 - 100,112,833 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0999,767,655 - 99,776,488 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera991,034,781 - 91,046,660 (+)NCBICelera
Cytogenetic Map9q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Capn10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69354
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.