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Gene: Capn10 (calpain 10) Rattus norvegicus
Symbol: Capn10
Name: calpain 10
Description: Exhibits SNARE binding activity; calcium-dependent cysteine-type endopeptidase activity; and cytoskeletal protein binding activity. Involved in several processes, including actin cytoskeleton reorganization; autophagy of mitochondrion; and response to glucose. Localizes to several cellular components, including the cell cortex; cytosol; and mitochondrion. Used to study type 2 diabetes mellitus. Biomarker of type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in obesity; pancreatic cancer; polycystic ovary syndrome; and type 2 diabetes mellitus. Orthologous to human CAPN10 (calpain 10); INTERACTS WITH 2,4-dinitrotoluene; acrylamide; arsenite(3-).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: calcium-activated neutral proteinase 10; calpain-10; CANP 10; MGC93346
Homo sapiens (human) : CAPN10 (calpain 10)  HGNC  Alliance
Mus musculus (house mouse) : Capn10 (calpain 10)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Capn10 (calpain 10)
Pan paniscus (bonobo/pygmy chimpanzee) : CAPN10 (calpain 10)
Canis lupus familiaris (dog) : CAPN10 (calpain 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Capn10 (calpain 10)
Sus scrofa (pig) : CAPN10 (calpain 10)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.09100,104,000 - 100,112,833 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9100,104,000 - 100,112,832 (+)Ensembl
Rnor_5.0999,767,655 - 99,776,488 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera991,034,781 - 91,046,660 (+)NCBICelera
Cytogenetic Map9q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Capn10
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69354
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.