Ppp1r14c (protein phosphatase 1, regulatory (inhibitor) subunit 14c) - Rat Genome Database

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Gene: Ppp1r14c (protein phosphatase 1, regulatory (inhibitor) subunit 14c) Rattus norvegicus
Analyze
Symbol: Ppp1r14c
Name: protein phosphatase 1, regulatory (inhibitor) subunit 14c
RGD ID: 620538
Description: Enables protein serine/threonine phosphatase inhibitor activity. Located in membrane. Orthologous to human PPP1R14C (protein phosphatase 1 regulatory inhibitor subunit 14C); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Kepi; kinase-enhanced PP1 inhibitor; MGC93087; PKC-potentiated PP1 inhibitory protein; protein phosphatase 1 regulatory subunit 14C
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8142,177,977 - 42,358,654 (+)NCBIGRCr8
mRatBN7.2139,773,403 - 39,886,970 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl139,773,403 - 39,886,956 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx140,299,808 - 40,413,279 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0146,287,020 - 46,400,487 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0140,376,091 - 40,489,622 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0139,811,314 - 39,923,071 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl139,811,314 - 39,923,057 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0141,159,898 - 41,272,182 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4134,004,772 - 34,118,105 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1134,008,256 - 34,121,036 (+)NCBI
Celera135,478,909 - 35,591,445 (+)NCBICelera
Cytogenetic Map1p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2-hydroxypropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
camptothecin  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
ciguatoxin CTX1B  (ISO)
clofibrate  (EXP)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dibutyl phthalate  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
FR900359  (ISO)
genistein  (ISO)
gentamycin  (EXP)
isobutanol  (ISO)
isoprenaline  (ISO)
lithium chloride  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
Nutlin-3  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
endomembrane system  (IEA)
membrane  (IDA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEPI, a PKC-dependent protein phosphatase 1 inhibitor regulated by morphine. Liu QR, etal., J Biol Chem 2002 Apr 12;277(15):13312-20.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334  


Genomics

Comparative Map Data
Ppp1r14c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8142,177,977 - 42,358,654 (+)NCBIGRCr8
mRatBN7.2139,773,403 - 39,886,970 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl139,773,403 - 39,886,956 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx140,299,808 - 40,413,279 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0146,287,020 - 46,400,487 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0140,376,091 - 40,489,622 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0139,811,314 - 39,923,071 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl139,811,314 - 39,923,057 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0141,159,898 - 41,272,182 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4134,004,772 - 34,118,105 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1134,008,256 - 34,121,036 (+)NCBI
Celera135,478,909 - 35,591,445 (+)NCBICelera
Cytogenetic Map1p11NCBI
PPP1R14C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386150,143,044 - 150,250,392 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6150,143,044 - 150,250,392 (+)EnsemblGRCh38hg38GRCh38
GRCh376150,464,180 - 150,571,528 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366150,505,881 - 150,613,221 (+)NCBINCBI36Build 36hg18NCBI36
Build 346150,556,346 - 150,663,605NCBI
Celera6151,198,793 - 151,306,443 (+)NCBICelera
Cytogenetic Map6q25.1NCBI
HuRef6148,029,989 - 148,136,641 (+)NCBIHuRef
CHM1_16150,728,261 - 150,835,613 (+)NCBICHM1_1
T2T-CHM13v2.06151,342,372 - 151,450,366 (+)NCBIT2T-CHM13v2.0
Ppp1r14c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39103,315,974 - 3,414,975 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl103,316,057 - 3,414,975 (+)EnsemblGRCm39 Ensembl
GRCm38103,365,974 - 3,464,978 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl103,366,057 - 3,464,975 (+)EnsemblGRCm38mm10GRCm38
MGSCv37106,881,566 - 6,980,391 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36106,881,566 - 6,980,391 (-)NCBIMGSCv36mm8
Celera103,301,562 - 3,400,112 (+)NCBICelera
Cytogenetic Map10A1NCBI
cM Map102.06NCBI
Ppp1r14c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543911,142,520 - 11,238,660 (-)NCBIChiLan1.0ChiLan1.0
PPP1R14C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25170,163,087 - 170,269,635 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16168,056,563 - 168,163,106 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06147,956,175 - 148,063,169 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16152,657,854 - 152,767,547 (+)NCBIpanpan1.1PanPan1.1panPan2
PPP1R14C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1140,710,826 - 40,797,413 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl140,710,992 - 40,795,889 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha141,549,480 - 41,635,462 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0140,892,922 - 40,979,148 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl140,892,922 - 40,978,116 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1140,768,624 - 40,854,688 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0140,612,465 - 40,698,436 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0141,116,047 - 41,202,074 (+)NCBIUU_Cfam_GSD_1.0
Ppp1r14c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946136,014,815 - 136,113,439 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364893,282,779 - 3,363,935 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364893,266,808 - 3,365,432 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP1R14C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl115,865,220 - 15,949,956 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1115,867,846 - 15,949,951 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2117,995,575 - 18,079,171 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP1R14C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11377,556,799 - 77,672,727 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1377,557,429 - 77,672,801 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604049,873,570 - 49,984,870 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp1r14c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247857,930,781 - 8,015,529 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247857,930,893 - 8,015,584 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:808
Count of miRNA genes:307
Interacting mature miRNAs:389
Transcripts:ENSRNOT00000022046
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1774611852746118Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1774612152746121Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12940927974409279Rat
70179Xhs2X-ray hypersensitivity QTL 23.2intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)1143965634Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)11037949255379492Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1694102251941022Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)1690935351909353Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11731537851816258Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)1690935351909353Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
5684999Bss102Bone structure and strength QTL 1025.57e-07tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)1690935351909353Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11282049457820494Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)12065642065656420Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12050832665508326Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)11168446456684464Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13456572679565726Rat

Markers in Region
AU048468  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2139,778,783 - 39,778,971 (+)MAPPERmRatBN7.2
Rnor_6.0139,816,695 - 39,816,882NCBIRnor6.0
Rnor_5.0141,165,279 - 41,165,466UniSTSRnor5.0
RGSC_v3.4134,010,153 - 34,010,340UniSTSRGSC3.4
Celera135,484,290 - 35,484,465UniSTS
Cytogenetic Map1p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 85 84 53 25 53 6 212 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000022046   ⟹   ENSRNOP00000022046
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl139,773,403 - 39,886,956 (+)Ensembl
Rnor_6.0 Ensembl139,811,314 - 39,923,057 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110642   ⟹   ENSRNOP00000092971
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl139,773,403 - 39,885,365 (+)Ensembl
RefSeq Acc Id: NM_133425   ⟹   NP_596916
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8142,179,523 - 42,293,071 (+)NCBI
mRatBN7.2139,773,403 - 39,886,970 (+)NCBI
Rnor_6.0139,811,314 - 39,923,071 (+)NCBI
Rnor_5.0141,159,898 - 41,272,182 (+)NCBI
RGSC_v3.4134,004,772 - 34,118,105 (+)RGD
Celera135,478,909 - 35,591,445 (+)RGD
Sequence:
RefSeq Acc Id: XM_039085420   ⟹   XP_038941348
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8142,211,343 - 42,292,838 (+)NCBI
mRatBN7.2139,805,329 - 39,886,955 (+)NCBI
RefSeq Acc Id: XM_063273005   ⟹   XP_063129075
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8142,177,977 - 42,358,654 (+)NCBI
RefSeq Acc Id: XR_010057354
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8142,212,467 - 42,291,327 (+)NCBI
RefSeq Acc Id: NP_596916   ⟸   NM_133425
- UniProtKB: Q8R4R9 (UniProtKB/Swiss-Prot),   A6KIK0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000022046   ⟸   ENSRNOT00000022046
RefSeq Acc Id: XP_038941348   ⟸   XM_039085420
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000092971   ⟸   ENSRNOT00000110642
RefSeq Acc Id: XP_063129075   ⟸   XM_063273005
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8R4R9-F1-model_v2 AlphaFold Q8R4R9 1-164 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689581
Promoter ID:EPDNEW_R106
Type:single initiation site
Name:Ppp1r14c_1
Description:protein phosphatase 1, regulatory subunit 14c
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0139,811,393 - 39,811,453EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620538 AgrOrtholog
BioCyc Gene G2FUF-61732 BioCyc
Ensembl Genes ENSRNOG00000016368 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055021424 UniProtKB/Swiss-Prot
  ENSRNOG00060000699 UniProtKB/Swiss-Prot
  ENSRNOG00065002604 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000022046.4 UniProtKB/Swiss-Prot
  ENSRNOT00000110642.1 UniProtKB/TrEMBL
  ENSRNOT00055036627 UniProtKB/Swiss-Prot
  ENSRNOT00060000794 UniProtKB/Swiss-Prot
  ENSRNOT00065003467 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.150.220 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7191557 IMAGE-MGC_LOAD
InterPro CPI-17 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CPI-17_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:171010 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:93087 IMAGE-MGC_LOAD
NCBI Gene 171010 ENTREZGENE
PANTHER PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 14C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR16188 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PP1_inhibitor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ppp1r14c PhenoGen
RatGTEx ENSRNOG00000016368 RatGTEx
  ENSRNOG00055021424 RatGTEx
  ENSRNOG00060000699 RatGTEx
  ENSRNOG00065002604 RatGTEx
Superfamily-SCOP SSF81790 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AIL6_RAT UniProtKB/TrEMBL
  A6KIK0 ENTREZGENE, UniProtKB/TrEMBL
  A6KIK1_RAT UniProtKB/TrEMBL
  PP14C_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Ppp1r14c  protein phosphatase 1, regulatory (inhibitor) subunit 14c    protein phosphatase 1, regulatory (inhibitor) subunit 14C  Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Ppp1r14c  protein phosphatase 1, regulatory (inhibitor) subunit 14C      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in brain, heart, and skeletal muscle 619697
gene_process inhibits the activity of serine/threonine type 1 protein phosphatase, PP1 619697
gene_regulation phosphorylated by PKC; mRNA up-regulated by both acute and chronic morphine treatments; 619697