Ugdh (UDP-glucose 6-dehydrogenase) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Ugdh (UDP-glucose 6-dehydrogenase) Rattus norvegicus
Analyze
Symbol: Ugdh
Name: UDP-glucose 6-dehydrogenase
RGD ID: 621879
Description: Enables UDP-glucose 6-dehydrogenase activity. Predicted to be involved in several processes, including UDP-glucuronate biosynthetic process; protein hexamerization; and proteoglycan biosynthetic process. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 84. Orthologous to human UGDH (UDP-glucose 6-dehydrogenase); PARTICIPATES IN congenital sucrase-isomaltase deficiency pathway; galactokinase deficiency pathway; GALE deficiency pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: UDP-Glc dehydrogenase; UDP-GlcDH; UDP-glucose dehydrogeanse; UDP-glucose dehydrogenase; UDPGDH
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81443,202,480 - 43,226,002 (+)NCBIGRCr8
mRatBN7.21442,848,704 - 42,872,351 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1442,848,854 - 42,872,354 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1443,202,670 - 43,226,148 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01444,502,588 - 44,526,066 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01442,982,708 - 43,006,181 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01444,479,614 - 44,502,845 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1444,479,614 - 44,502,845 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01444,299,226 - 44,322,226 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41445,542,781 - 45,570,961 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11445,545,171 - 45,573,352 (+)NCBI
Celera1441,999,555 - 42,023,022 (+)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-benzofuran  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-hydroxyethyl methacrylate  (ISO)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-chloropropane-1,2-diol  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
5-fluorouracil  (ISO)
9-cis-retinoic acid  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
actinomycin D  (ISO)
aldrin  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
Azoxymethane  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cadmium sulfate  (ISO)
caffeine  (ISO)
captan  (ISO)
carbamazepine  (EXP)
carbon nanotube  (ISO)
celastrol  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
coumarin  (EXP)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
deguelin  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dichloroacetic acid  (ISO)
dioxygen  (EXP)
diquat  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (EXP,ISO)
eugenol  (ISO)
felbamate  (EXP)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
fumonisin B1  (ISO)
furan  (EXP,ISO)
gabapentin  (EXP)
gedunin  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glyphosate  (ISO)
griseofulvin  (ISO)
inulin  (ISO)
isoflavones  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
ketamine  (EXP)
lead diacetate  (ISO)
lead(II) chloride  (ISO)
leflunomide  (EXP)
mercury dichloride  (EXP)
methylisothiazolinone  (ISO)
methylseleninic acid  (ISO)
microcystin-LR  (ISO)
N(4)-hydroxycytidine  (ISO)
N-acetyl-L-cysteine  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methylformamide  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
naphthalene-1,5-diamine  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
Nutlin-3  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenformin  (EXP)
phenobarbital  (EXP,ISO)
phenytoin  (EXP)
piperine  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (ISO)
pyrogallol  (ISO)
quercetin  (EXP)
rifampicin  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sulforaphane  (ISO)
tanespimycin  (ISO)
tert-butyl ethyl ether  (EXP)
tetrachloromethane  (EXP,ISO)
thiabendazole  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
tolbutamide  (EXP)
topotecan  (EXP)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (ISO)
nucleus  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Characterization of human UDP-glucose dehydrogenase. CYS-276 is required for the second of two successive oxidations. Sommer BJ, etal., J Biol Chem 2004 May 28;279(22):23590-6. Epub 2004 Mar 24.
12. Molecular cloning and characterization of the human and mouse UDP-glucose dehydrogenase genes. Spicer AP, etal., J Biol Chem 1998 Sep 25;273(39):25117-24.
13. Enhancement of UDP-glucuronyltransferase, UDP-glucose dehydrogenase, and glutathione S-transferase activities in rat liver by dietary administration of eugenol. Yokota H, etal., Biochem Pharmacol 1988 Mar 1;37(5):799-802.
Additional References at PubMed
PMID:14505572   PMID:15755804   PMID:16396499   PMID:16641100   PMID:23533145   PMID:25416956   PMID:27966912   PMID:32001716  


Genomics

Comparative Map Data
Ugdh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81443,202,480 - 43,226,002 (+)NCBIGRCr8
mRatBN7.21442,848,704 - 42,872,351 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1442,848,854 - 42,872,354 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1443,202,670 - 43,226,148 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01444,502,588 - 44,526,066 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01442,982,708 - 43,006,181 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01444,479,614 - 44,502,845 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1444,479,614 - 44,502,845 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01444,299,226 - 44,322,226 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41445,542,781 - 45,570,961 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11445,545,171 - 45,573,352 (+)NCBI
Celera1441,999,555 - 42,023,022 (+)NCBICelera
Cytogenetic Map14p11NCBI
UGDH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38439,498,755 - 39,527,439 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl439,498,755 - 39,528,311 (-)EnsemblGRCh38hg38GRCh38
GRCh37439,500,375 - 39,529,059 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36439,176,770 - 39,205,606 (-)NCBINCBI36Build 36hg18NCBI36
Build 34439,322,945 - 39,351,539NCBI
Celera439,938,164 - 39,967,004 (-)NCBICelera
Cytogenetic Map4p14NCBI
HuRef438,825,375 - 38,854,230 (-)NCBIHuRef
CHM1_1439,499,802 - 39,528,655 (-)NCBICHM1_1
T2T-CHM13v2.0439,468,409 - 39,497,229 (-)NCBIT2T-CHM13v2.0
Ugdh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39565,570,550 - 65,593,185 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl565,570,564 - 65,593,292 (-)EnsemblGRCm39 Ensembl
GRCm38565,413,207 - 65,435,842 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl565,413,221 - 65,435,949 (-)EnsemblGRCm38mm10GRCm38
MGSCv37565,804,460 - 65,827,081 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36565,692,356 - 65,714,977 (-)NCBIMGSCv36mm8
Celera562,689,905 - 62,712,959 (-)NCBICelera
Cytogenetic Map5C3.1NCBI
cM Map533.67NCBI
Ugdh
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554437,868,893 - 7,882,129 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554437,868,893 - 7,882,136 (+)NCBIChiLan1.0ChiLan1.0
UGDH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2339,688,142 - 39,716,993 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1439,880,751 - 39,909,008 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0433,827,532 - 33,856,204 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1439,679,915 - 39,708,215 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl439,681,300 - 39,708,215 (-)Ensemblpanpan1.1panPan2
UGDH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1372,935,532 - 72,964,151 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl372,839,920 - 72,963,208 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha375,481,824 - 75,511,112 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0373,708,348 - 73,737,653 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl373,553,586 - 73,737,645 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1372,974,965 - 73,004,279 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0373,121,242 - 73,150,553 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0373,507,747 - 73,537,066 (+)NCBIUU_Cfam_GSD_1.0
Ugdh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528539,179,915 - 39,207,994 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364827,089,621 - 7,118,284 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364827,090,241 - 7,118,315 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UGDH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl830,725,288 - 30,759,326 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1830,725,281 - 30,759,359 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2832,340,313 - 32,374,310 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UGDH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12710,781,324 - 10,810,595 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2710,781,502 - 10,810,817 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604757,174,192 - 57,202,679 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ugdh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248704,782,252 - 4,799,703 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248704,768,307 - 4,801,333 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ugdh
73 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:501
Count of miRNA genes:247
Interacting mature miRNAs:296
Transcripts:ENSRNOT00000003691
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
10755459Coatc15Coat color QTL 150.01681coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)141983694464836944Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143999825175582726Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143088377768757901Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
7387267Uae42Urinary albumin excretion QTL 420.61urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)142216796767167967Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141854133263541332Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14826709053267090Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat

Markers in Region
D14Got48  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21442,854,995 - 42,855,275 (+)MAPPERmRatBN7.2
Rnor_6.01444,485,742 - 44,486,023NCBIRnor6.0
Rnor_5.01444,305,152 - 44,305,433UniSTSRnor5.0
RGSC_v3.41445,549,232 - 45,549,514RGDRGSC3.4
RGSC_v3.41445,549,233 - 45,549,514UniSTSRGSC3.4
RGSC_v3.11445,551,623 - 45,551,905RGD
Celera1442,005,664 - 42,005,946UniSTS
Cytogenetic Map14p11UniSTS
RH134455  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21442,871,941 - 42,872,157 (+)MAPPERmRatBN7.2
Rnor_6.01444,502,436 - 44,502,651NCBIRnor6.0
Rnor_5.01444,321,817 - 44,322,032UniSTSRnor5.0
RGSC_v3.41445,570,552 - 45,570,767UniSTSRGSC3.4
Celera1442,022,613 - 42,022,828UniSTS
Cytogenetic Map14p11UniSTS
RH143560  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21442,848,781 - 42,848,924 (+)MAPPERmRatBN7.2
Rnor_6.01444,479,540 - 44,479,682NCBIRnor6.0
Rnor_5.01444,299,152 - 44,299,294UniSTSRnor5.0
RGSC_v3.41445,542,707 - 45,542,849UniSTSRGSC3.4
Celera1441,999,481 - 41,999,623UniSTS
Cytogenetic Map14p11UniSTS
BF403257  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21442,849,132 - 42,849,288 (+)MAPPERmRatBN7.2
Rnor_6.01444,479,891 - 44,480,046NCBIRnor6.0
Rnor_5.01444,299,503 - 44,299,658UniSTSRnor5.0
RGSC_v3.41445,543,058 - 45,543,213UniSTSRGSC3.4
Celera1441,999,832 - 41,999,987UniSTS
Cytogenetic Map14p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000003691   ⟹   ENSRNOP00000003691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1442,848,854 - 42,872,354 (+)Ensembl
Rnor_6.0 Ensembl1444,479,614 - 44,502,845 (+)Ensembl
RefSeq Acc Id: NM_031325   ⟹   NP_112615
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81443,202,518 - 43,226,002 (+)NCBI
mRatBN7.21442,848,856 - 42,872,351 (+)NCBI
Rnor_6.01444,479,614 - 44,502,845 (+)NCBI
Rnor_5.01444,299,226 - 44,322,226 (+)NCBI
RGSC_v3.41445,542,781 - 45,570,961 (+)RGD
Celera1441,999,555 - 42,023,022 (+)RGD
Sequence:
RefSeq Acc Id: XR_005493021
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81443,202,480 - 43,221,026 (+)NCBI
mRatBN7.21442,848,704 - 42,867,375 (+)NCBI
Protein Sequences
Protein RefSeqs NP_112615 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAA28215 (Get FASTA)   NCBI Sequence Viewer  
  EDL90061 (Get FASTA)   NCBI Sequence Viewer  
  EDL90062 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000003691.3
GenBank Protein O70199 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_112615   ⟸   NM_031325
- UniProtKB: O70199 (UniProtKB/Swiss-Prot),   A6JDD9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000003691   ⟸   ENSRNOT00000003691
Protein Domains
UDP-glucose/GDP-mannose dehydrogenase C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O70199-F1-model_v2 AlphaFold O70199 1-493 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699314
Promoter ID:EPDNEW_R9839
Type:multiple initiation site
Name:Ugdh_1
Description:UDP-glucose 6-dehydrogenase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01444,479,615 - 44,479,675EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621879 AgrOrtholog
BioCyc Gene G2FUF-15746 BioCyc
BioCyc Pathway PWY-7346 [UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)] BioCyc
BioCyc Pathway Image PWY-7346 BioCyc
Ensembl Genes ENSRNOG00000002643 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003691.4 UniProtKB/TrEMBL
Gene3D-CATH Cytochrome c1, transmembrane anchor, C-terminal UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro 6-PGluconate_DH-like_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UDP-Glc/GDP-Man UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UDP-Glc/GDP-Man_DH_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UDP-Glc/GDP-Man_DH_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UDP-Glc/GDP-Man_DH_dimer UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UDP-Glc/GDP-Man_DH_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UDPglc_DH_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:83472 UniProtKB/Swiss-Prot
NCBI Gene 83472 ENTREZGENE
PANTHER PTHR11374 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UDP-GLUCOSE 6-DEHYDROGENASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam UDPG_MGDP_dh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UDPG_MGDP_dh_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UDPG_MGDP_dh_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ugdh PhenoGen
PIRSF UDPglc_DH_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UDPglc_GDPman_dh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002643 RatGTEx
SMART UDPG_MGDP_dh_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48179 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52413 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6JDD9 ENTREZGENE, UniProtKB/TrEMBL
  A6JDE0_RAT UniProtKB/TrEMBL
  G3V6C4_RAT UniProtKB/TrEMBL
  O70199 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-01 Ugdh  UDP-glucose 6-dehydrogenase  Ugdh  UDP-glucose dehydrogenase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Ugdh  UDP-glucose dehydrogenase    UDP-glucose dehydrogeanse  Name updated 1299863 APPROVED
2002-08-07 Ugdh  UDP-glucose dehydrogeanse      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference